Experts debate whether hyperinsulinemia is the primary defect that causes type 2 diabetes
Is hyperinsulinemia the primary defect that results in type 2 diabetes? Or is it something else—hyperglycemia, beta cell defects, genetics? “The big question is whether insulin resistance is primary or if hyperinsulinemia stimulates insulin resistance,” said James D. Johnson, PhD, Professor of Cellular and Physiological Sciences and Board Chair, Institute for Personalized Therapeutic Nutrition, University […]
Insulin resistance–obesity–hyperinsulinemia–which comes first and what causes what?
A fresh consideration of an enduring debate in diabetes An international team led by Dr. Søs Skovsø, a recent post-doctoral fellow in the lab of LSI Deputy Director Dr. James Johnson, showed a causal connection between dysfunctional beta-cells and glucose-stimulated hyperinsulinemia, both of which are critical features of obesity and early type 2 diabetes. The […]
Dr. James Johnson appointed Deputy Director of the LSI
With great pleasure we announce the appointment of our own Dr. Jim Johnson as the Deputy Director of the LSI, commencing January 2021. Dr. Johnson brings a wealth of knowledge to the LSI leadership team. Renowned for the broad scope of his β-cell biology and diabetes research, Jim is noted for using innovative approaches to […]
Jim Johnson talks beta cell biology on BC Diabetes Research Network podcast
LSI’s Dr. Jim Johnson is the featured guest on part 3 of the BC Diabetes Network’s podcast series. In this segment, host Krista Lamb interviews Dr. Johnson about beta cell biology, and the whole-body impacts of dysfunctional beta cells using multi-disciplinary approaches. Their conversation covers the recent shift towards beta cell research in understanding both […]