Our research mission is to perform innovative, interdisciplinary science focused on discovering the fundamental biological mechanisms underlying health and disease — and to propel this knowledge towards translation into new therapies. As the largest institute of its kind in Canada, the LSI is positioned to take a lead in unraveling medicine’s greatest challenges and providing the evidence needed to achieve better health outcomes for Canadians.
Research in the LSI is focused on 9 disease or technology focused research groups. Members of these multi-disciplinary research groups conduct vibrant, biomedical-based research on diabetes, cardiovascular disease, immune responses, infectious disease, cancer biology, developmental disorders, bacterial regulation, neuroscience, structural biology, and molecular epigenetics. In addition to specific disease-oriented research, the LSI focuses on fundamental research in the biomedical sciences aimed at identifying, characterizing, and understanding the molecular mechanisms that govern gene expression, protein structure-function, environmental microbiology, and how key cellular and developmental processes go awry in human disease.