Research & Training

Samples in the lab being handled.

Research Innovation

Our research mission is to uncover the fundamental biological mechanisms of health and disease and translate those discoveries into new therapies. As Canada's largest institute of its kind, the LSI leads in addressing medicine's greatest challenges and improving health outcomes.

Researcher working with samples in the lab.

Our Labs

At the LSI, our faculty members are recognized as some of Canada's top researchers, receiving prestigious awards at the institutional, provincial, and national levels. Discover cutting-edge research by exploring our labs, with options to search and filter by topic or department.

LSI researchers walking and talking.

Recent Publications

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Glycemic control and blood product quality of Canadian blood donors with diabetes

Researchers: Devine, J Johnson

Broad-spectrum bactericidal synergy of silver-cannabichromene-cannabigerol triple combinations against healthcare-associated pathogens

Researcher: Thompson

Persistent organic pollutant concentrations in human pancreas correlate with markers of beta cell dysfunction

Researcher: J Johnson

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis

Researcher: Rideout

Advancing regenerative medicine with RNA nanotechnology for chronic and end organ diseases

Researcher: Hedtrich

Cell type specific allometry controls sex-differences in Drosophila organ size

Researcher: Rideout

Integrated clinical and postmortem profiling in schizophrenia reveals a cognitive subtype linked to cerebrovascular disease

Researcher: Cembrowski

Structural enzymology of a Fusarium graminearum aldehyde oxidase reveals a distinct active-site and reactivity versus its paralog galactose oxidase

Researcher: Van Petegem

CSF1R+ macrophage and osteoclast depletion impairs neural crest proliferation and craniofacial morphogenesis

Researcher: Rosin

Hybrid Lipid Nanoparticles Containing Iron Oxide Nanoparticles and Doxorubicin

Researcher: Cullis

Modification of internal RNA domains from the long non-coding RNA XIST refines roles in silencing and heterochromatin recruitment

Researcher: Brown

Characterization of acetovanillone degradation in wild-type and engineered Rhodococcus aromaticivorans RHA1

Researcher: Eltis

Role of the anti-Shine-Dalgarno sequence of 16S rRNA in Flavobacterium johnsoniae

Researcher: Foster

Uniform bacterial genetic diversity along the gut

Researcher: Tropini

Interactions between immuno-epidemiology and individual decision-making for nonpharmaceutical interventions

Researcher: Abraham