LSI Pub Corner

LSI Pub Corner

Find the latest publications from LSI’s researchers here:

2018

Feb 19 Pubcrawler Hits:

1. Millar D, Murphy L, Labrie A, Maurer-Spurej E. Routine Screening Method for Microparticles in Platelet Transfusions. J Vis Exp. 2018 Jan 31. doi: 10.3791/56893. PMID: 29443045. https://www.ncbi.nlm.nih.gov/pubmed/29443045

2. Dommerholt MB, Dionne DA, Hutchinson DF, Kruit JK, Johnson JD. Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage. J Endocrinol. 2018 Feb 9. doi: 10.1530/JOE-17-0505. [Epub ahead of print] PMID: 29439088. https://www.ncbi.nlm.nih.gov/pubmed/29439088

3. Jagdeo JM, Dufour A, Klein T, Solis N, Kleifeld O, Kizhakkedathu J, Luo H, Overall CMJan E. N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection. J Virol. 2018 Feb 7. doi: 10.1128/JVI.02211-17. [Epub ahead of print] PMID: 29437971. https://www.ncbi.nlm.nih.gov/pubmed/29437971

4. Farr Zuend C, Nomellini JF, Smit JHorwitz MS. Generation of a Dual-Target, Safe, Inexpensive Microbicide that Protects Against HIV-1 and HSV-2 Disease.  2018 Feb 12;8(1):2786. doi: 10.1038/s41598-018-21134-1. PMID: 29434285.  https://www.ncbi.nlm.nih.gov/pubmed/29434285

5. Johnston ZC, Bellingham M, Filis P, Soffientini U, Hough D, Bhattacharya S, Simard M, Hammond GL, King P, O'Shaughnessy PJ, Fowler PA. The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester. BMC Med. 2018 Feb 12;16(1):23. doi: 10.1186/s12916-018-1009-7. PMID: 29429410. https://www.ncbi.nlm.nih.gov/pubmed/29429410

Feb 12 Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Simpson EM, Brown CJ. Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse. Hum Mol Genet. 2018 Feb 1. doi: 10.1093/hmg/ddy039. [Epub ahead of print] PubMed PMID: 29401310. https://www.ncbi.nlm.nih.gov/pubmed/29401310?dopt=Abstract

2. Saber N, Bruin JE, O'Dwyer S, Schuster H, Rezania A, Kieffer TJ. Sex differences in maturation of human embryonic stem cell-derived beta cells in mice. Endocrinology. 2018 Feb 5. doi: 10.1210/en.2018-00048. [Epub ahead of print] PubMed PMID: 29420708. https://www.ncbi.nlm.nih.gov/pubmed/29420708?dopt=Abstract

3. De Silva E, Kim H. Drug-induced thrombocytopenia: Focus on platelet apoptosis. Chem Biol Interact. 2018 Feb 1. pii: S0009-2797(17)30840-2. doi: 10.1016/j.cbi.2018.01.015. [Epub ahead of print] Review. PubMed PMID: 29410286. https://www.ncbi.nlm.nih.gov/pubmed/29410286?dopt=Abstract

4. Hayes M, Choudhary V, Ojha N, Shin JJ, Han GS, Carman GM, Loewen CJ, Prinz WA, Levine T. Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes. Microb Cell. 2017 Dec 28;5(2):88-103. doi: 10.15698/mic2018.02.614. PubMed PMID: 29417057; PubMed Central PMCID: PMC5798408. https://www.ncbi.nlm.nih.gov/pubmed/29417057?dopt=Abstract

5. Heger TJ, Giesbrecht IJW, Gustavsen J, Del Campo J, Kellogg CTE, Hoffman KM, Lertzman K, Mohn WW, Keeling PJ. High-throughput environmental sequencing reveals high diversity of litter and moss associated protist communities along a gradient of drainage and tree productivity. Environ Microbiol. 2018 Feb 7. doi: 10.1111/1462-2920.14061. [Epub ahead of print] PubMed PMID: 29417706. https://www.ncbi.nlm.nih.gov/pubmed/29417706?dopt=Abstract

Feb 05 Pubcrawler Hits:

1. Fakhraee M, Crowe SA, Katsev S. Sedimentary sulfur isotopes and Neoarchean ocean oxygenation. Sci Adv. 2018 Jan 24;4(1):e1701835. doi: 10.1126/sciadv.1701835. eCollection 2018 Jan. PubMed PMID: 29376118; PubMed Central PMCID: PMC5783677. https://www.ncbi.nlm.nih.gov/pubmed/29376118?dopt=Abstract

2. Devine DV. Pathogen Inactivation Strategies to Improve Blood Safety: Let's Not Throw Pathogen-Reduced Platelets Out With Their Bath Water. JAMA Oncol. 2018 Feb doi: 10.1001/jamaoncol.2017.4949. [Epub ahead of print] PubMed PMID: 29392303. https://www.ncbi.nlm.nih.gov/pubmed/29392303?dopt=Abstract

3. Wang JC, Bolger-Munro M, Gold MR. Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods Mol Biol. 2018;1707:131-161. doi: 10.1007/978-1-4939-7474-0_10. PubMed PMID: 29388105. https://www.ncbi.nlm.nih.gov/pubmed/29388105?dopt=Abstract

4. Holert J, Cardenas E, Bergstrand LH, Zaikova E, Hahn AS, Hallam SJ, Mohn WW. Metagenomes Reveal Global Distribution of Bacterial Steroid Catabolism in Natural, Engineered, and Host Environments. MBio. 2018 Jan 30;9(1). pii:e02345-17. doi: 10.1128/mBio.02345-17. PubMed PMID: 29382738. https://www.ncbi.nlm.nih.gov/pubmed/29382738?dopt=Abstract

Jan 29 Pubcrawler Hits:

1. Kumar P, Kizhakkedathu JN, Straus SK. Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo. Biomolecules. 2018 Jan 19;8(1). pii: E4. doi: 10.3390/biom8010004. Review. PubMed PMID: 29351202. https://www.ncbi.nlm.nih.gov/pubmed/29351202?dopt=Abstract

2. Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut. 2018 Jan 23. pii: gutjnl-2017-314426. doi: 10.1136/gutjnl-2017-314426. [Epub ahead of print] PubMed PMID: 29363536. https://www.ncbi.nlm.nih.gov/pubmed/29363536?dopt=Abstract

3. Kaiser JC, King AN, Grigg JC, Sheldon JR, Edgell DR, Murphy MEP, Brinsmade SR, Heinrichs DE. Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide. PLoS Genet. 2018 Jan 22;14(1):e1007159. doi: 10.1371/journal.pgen.1007159. [Epub ahead of print] PubMed PMID: 29357354. https://www.ncbi.nlm.nih.gov/pubmed/29357354?dopt=Abstract

4. Campiglio M, Costé de Bagneaux P, Ortner NJ, Tuluc P, Van Petegem F, Flucher BE. STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation. Proc Natl Acad Sci U S A. 2018 Jan 23. pii: 201715997. doi: 10.1073/pnas.1715997115. [Epub ahead of print] PubMed PMID: 29363593. https://www.ncbi.nlm.nih.gov/pubmed/29363593?dopt=Abstract

5. Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS. PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance. J Antimicrob Chemother. 2018 Jan 19. doi: 10.1093/jac/dkx531. [Epub ahead of print] PubMed PMID: 29360990. https://www.ncbi.nlm.nih.gov/pubmed/29360990?dopt=Abstract

6. Petrelli B, Weinberg J, Hicks GG. Effects of Prenatal Alcohol Exposure (PAE): Insights into FASD using PAE Mouse Models. Biochem Cell Biol. 2018 Jan 25. doi: 10.1139/bcb-2017-0280. [Epub ahead of print] PubMed PMID: 29370535. https://www.ncbi.nlm.nih.gov/pubmed/29370535?dopt=Abstract

Jan 22 Pubcrawler Hits:

1. Macdonald LC, Kim RY, Kurata HT, Fedida D. Probing the molecular basis of hERG drug block with unnatural amino acids. Sci Rep. 2018 Jan 10;8(1):289. doi: 10.1038/s41598-017-18448-x. PubMed PMID: 29321549; PubMed Central PMCID: PMC5762913. https://www.ncbi.nlm.nih.gov/pubmed/29321549?dopt=Abstract

2. Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S. Transmembrane Pickets onnect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell.  018 Jan 11;172(1-2):305-317.e10. doi: 10.1016/j.cell.2017.12.023. PubMed PMID: 29328918. https://www.ncbi.nlm.nih.gov/pubmed/29328918?dopt=Abstract

3. Bi C, Tham DKL, Perronnet C, Joshi B, Nabi IR, Moukhles H. The Oxidative Stress-Induced Increase in the Membrane Expression of the Water-Permeable Channel Aquaporin-4 in Astrocytes Is Regulated by Caveolin-1 Phosphorylation. Front Cell Neurosci. 2017 Dec 20;11:412. doi: 10.3389/fncel.2017.00412. eCollection 2017. PubMed PMID: 29326556; PubMed Central PMCID: PMC5742350. https://www.ncbi.nlm.nih.gov/pubmed/29326556?dopt=Abstract

4. Lussier AA, Morin AM, MacIsaac JL, Salmon J, Weinberg J, Reynolds JN, Pavlidis P, Chudley AE, Kobor MS. DNA methylation as a predictor of fetal alcohol spectrum disorder. Clin Epigenetics. 2018 Jan 12;10:5. doi: 10.1186/s13148-018-0439-6. eCollection 2018. PubMed PMID: 29344313; PubMed Central PMCID: PMC5767049. https://www.ncbi.nlm.nih.gov/pubmed/29344313?dopt=Abstract

5. Dalwadi U, Yip CK. Structural insights into the function of Elongator. Cell Mol Life Sci. 2018 Jan 13. doi: 10.1007/s00018-018-2747-6. [Epub ahead of print] Review. PubMed PMID: 29332244. https://www.ncbi.nlm.nih.gov/pubmed/29332244?dopt=Abstract

Jan 15 Pubcrawler Hits:

1. Linde C, Cleland JGF, Gold MR, Claude Daubert J, Tang ASL, Young JB, Sherfesee L, Abraham WT. The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. Eur J Heart Fail. 2018 Jan 4. doi: 10.1002/ejhf.1133. [Epub ahead of print] PubMed PMID: 29314424. https://www.ncbi.nlm.nih.gov/pubmed/29314424?dopt=Abstract

2. Macdonald SS, Patel A, Larmour VLC, Morgan-Lang C, Hallam SJ, Mark BL, WithersSG. Structural and mechanistic analysis of a β-glycoside phosphorylase identified by screening a metagenomic library. J Biol Chem. 2018 Jan 9. pii: jbc.RA117.000948. doi: 10.1074/jbc.RA117.000948. [Epub ahead of print] PubMed PMID: 29317495. https://www.ncbi.nlm.nih.gov/pubmed/29317495?dopt=Abstract

3. Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH. A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses. Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4. PubMed PMID: 29311608; PubMed Central PMCID: PMC5758616. https://www.ncbi.nlm.nih.gov/pubmed/29311608?dopt=Abstract

4. Lee-Sayer SSM, Maeshima N, Dougan MN, Dahiya A, Arif AA, Dosanjh M, Maxwell CA, Johnson P. Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells. Eur J Immunol. 2018 Jan 8. doi: 1002/eji.201747263. [Epub ahead of print] PubMed PMID: 29315518. https://www.ncbi.nlm.nih.gov/pubmed/29315518?dopt=Abstract

5. Solis N, Overall CM. Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS). Methods Mol Biol. 2018;1731:15-28. doi:10.1007/978-1-4939-7595-2_2. PubMed PMID: 29318539. https://www.ncbi.nlm.nih.gov/pubmed/29318539?dopt=Abstract

6. Grieco TM, Richman JM. Coordination of bilateral tooth replacement in the juvenile gecko is continuous with in ovo patterning. Evol Dev. 2018 Jan 10. doi: 1111/ede.12247. [Epub ahead of print] PubMed PMID: 29318754. https://www.ncbi.nlm.nih.gov/pubmed/29318754?dopt=Abstract

7. Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y. Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages. Sci Rep. 2018 Jan 9;8(1):155. doi: 10.1038/s41598-017-18547-9. PubMed PMID: 29317718. https://www.ncbi.nlm.nih.gov/pubmed/29317718?dopt=Abstract

Jan 8 Pubcrawler Hits:

1. Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. PubMed PMID: 29296696; PubMed Central PMCID: PMC5744055. https://www.ncbi.nlm.nih.gov/pubmed/29296696?dopt=Abstract

Jan 1 Pubcrawler Hits:

1. Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, Brömme D. Tanshinones: A novel class of ectosteric anti-resorptives. Br J Pharmacol. 2017 Dec 26. doi: 10.1111/bph.14133. [Epub ahead of print] PubMed PMID: 29278432. https://www.ncbi.nlm.nih.gov/pubmed/29278432?dopt=Abstract
2. Galibert M, Wartenberg M, Lecaille F, Saidi A, Mavel S, Joulin-Giet A, Korkmaz B, Brömme D, Aucagne V, Delmas AF, Lalmanach G. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. Eur J Med Chem. 2017 Dec 7;144:201-210. doi: 10.1016/j.ejmech.2017.12.012. [Epub ahead of print] PubMed PMID: 29272750. https://www.ncbi.nlm.nih.gov/pubmed/29272750?dopt=Abstract
3. Simard M, Underhill C, Hammond GL. Functional Implications of Corticosteroid-binding Globulin N-Glycosylation. J Mol Endocrinol. 2017 Dec 22. pii: JME-17-0234. doi: 10.1530/JME-17-0234. [Epub ahead of print] PubMed PMID: 29273683. https://www.ncbi.nlm.nih.gov/pubmed/29273683?dopt=Abstract
4. Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. 2017 Dec 19. pii: S0016-5085(17)36711-2. doi: 10.1053/j.gastro.2017.12.007. [Epub ahead of print] PubMed PMID: 29273451. https://www.ncbi.nlm.nih.gov/pubmed/29273451?dopt=Abstract

2017

Dec 25 Pubcrawler Hits:

1. Klein T, Eckhard U, Dufour A, Solis N, Overall CM. Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification. Chem Rev. 2017 Dec 21. doi: 10.1021/acs.chemrev.7b00120. [Epub ahead of print] PubMed PMID: 29265812. https://www.ncbi.nlm.nih.gov/pubmed/29265812?report=&dispmax=200&tool=PubCrawler_1.3

2. Urtatiz O, Samani AMV, Kopp JL, Van Raamsdonk CD. Rapid melanoma induction in mice expressing oncogenic Braf(V600E) using Mitf-cre. Pigment Cell Melanoma Res. 2017 Dec 20. doi: 10.1111/pcmr.12680. [Epub ahead of print] PubMed PMID: 29266793. https://www.ncbi.nlm.nih.gov/pubmed/29266793?report=&dispmax=200&tool=PubCrawler_1.3

3. Raineki C, Ellis L, Weinberg J. Impact of adolescent stress on the expression of stress-related receptors in the hippocampus of animals exposed to alcohol prenatally. Hippocampus. 2017 Dec 18. doi: 10.1002/hipo.22823. [Epub ahead of print] PubMed PMID: 29251811. https://www.ncbi.nlm.nih.gov/pubmed/29251811?report=&dispmax=200&tool=PubCrawler_1.3

Dec 18 Pubcrawler Hits:

1. Garner SRC, Castellanos MC, Baillie K, Lian T, Allan DW. Drosophila female-specific Ilp7 motoneurons are generated by Fruitless-dependent cell death in males and a double-assurance survival role for Transformer in females. Development. 2017 Dec 11. pii: dev.150821. doi: 10.1242/dev.150821. [Epub ahead of print] PubMed PMID: 29229771. https://www.ncbi.nlm.nih.gov/pubmed/29229771?dopt=Abstract

2. Chen CCL, Goyal P, Karimi MM, Abildgaard MH, Kimura H, Lorincz MC. H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2. Genome Res. 2017 Dec 11. doi: 10.1101/gr.224717.117. [Epub ahead of print] PubMed PMID: 29229671. https://www.ncbi.nlm.nih.gov/pubmed/29229671?dopt=Abstract

Dec 11 Pubcrawler Hits:

1. Ho JCH, Pawar SV, Hallam SJ, Yadav VG. An Improved Whole-Cell Biosensor for the Discovery of Lignin-Transforming Enzymes in Functional Metagenomic Screens. ACS Synth Biol. 2017 Dec 4. doi: 10.1021/acssynbio.7b00412. [Epub ahead of print] PubMed PMID: 29182267. https://www.ncbi.nlm.nih.gov/pubmed/29182267?dopt=Abstract

2. Gemmel M, Harmeyer D, Bögi E, Fillet M, Hill LA, Hammond GL, Charlier TD, Pawluski JL. Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam. Behav Brain Res. 2017 Dec 5. pii: S0166-4328(17)31601-7. doi: 10.1016/j.bbr.2017.11.038. [Epub ahead of print] PubMed PMID: 29203333. https://www.ncbi.nlm.nih.gov/pubmed/29203333?dopt=Abstract

3. Burian J, Thompson CJ. Regulatory genes coordinating antibiotic-induced changes in promoter activity and early transcriptional termination of the mycobacterial intrinsic resistance gene whiB7. Mol Microbiol. 2017 Dec 4. doi: 10.1111/mmi.13890. [Epub ahead of print] PubMed PMID: 29205551. https://www.ncbi.nlm.nih.gov/pubmed/29205551?dopt=Abstract

Dec 04 Pubcrawler Hits:

1. Martin WF, Bryant DA, Beatty JT. A physiological perspective on the origin and evolution of photosynthesis. FEMS Microbiol Rev. 2017 Nov 21. doi: 10.1093/femsre/fux056. [Epub ahead of print] PubMed PMID: 29177446. https://www.ncbi.nlm.nih.gov/pubmed/29177446?dopt=Abstract

2. Pachiadaki MG, Sintes E, Bergauer K, Brown JM, Record NR, Swan BK, Mathyer ME, Hallam SJ, Lopez-Garcia P, Takaki Y, Nunoura T, Woyke T, Herndl GJ, Stepanauskas R. Major role of nitrite-oxidizing bacteria in dark ocean carbon fixation. Science. 2017 Nov 4; 358(6366):1046-1051. doi: 10.1126/science.aan8260. PubMed PMID: 29170234. https://www.ncbi.nlm.nih.gov/pubmed/29170234?dopt=Abstract

3. Paik YK, Overall CM, Deutsch EW, Van Eyk JE, Omenn GS. Progress and Future Direction of Chromosome-Centric Human Proteome Project. J Proteome Res. 2017 Dec 1;16(12):4253-4258. doi: 10.1021/acs.jproteome.7b00734. PubMed PMID: 29191025. https://www.ncbi.nlm.nih.gov/pubmed/29191025?dopt=Abstract

4. Tal A, Greenberg D, Av-Gay Y, Golan-Tripto I, Feinstein Y, Ben-Shimol S, Dagan R, Goldbart AD. Nitric oxide inhalations in bronchiolitis: A pilot, randomized, double-blinded, controlled trial. Pediatr Pulmonol. 2017 Nov 27. doi: 10.1002/ppul.23905. [Epub ahead of print] PubMed PMID: 29178284. https://www.ncbi.nlm.nih.gov/pubmed/29178284?dopt=Abstract

Nov 27 Pubcrawler Hits:

1. Samarasekera GDNG, Auld VJ. C-terminal Src kinase (Csk) regulates the tricellular junction protein Gliotactin independent of Src. Mol Biol Cell. 2017 Nov 22. pii: mbc.E17-04-0251. doi: 10.1091/mbc.E17-04-0251. [Epub ahead of print] PubMed PMID: 29167383. https://www.ncbi.nlm.nih.gov/pubmed/29167383?dopt=Abstract

2. Hou P, Eldstrom J, Shi J, Zhong L, McFarland K, Gao Y, Fedida D, Cui J.Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening. Nat Commun. 2017 Nov 23;8(1):1730. doi: 10.1038/s41467-017-01911-8. PubMed PMID: 29167462. https://www.ncbi.nlm.nih.gov/pubmed/29167462?dopt=Abstract

3. Molday LL, Wahl D, Sarunic M, Molday RS. Localization and Functional Characterization of the p.Asn965Ser (N965S) ABCA4 Variant in Mice Reveal Pathogenic Mechanisms Underlying Stargardt Macular Degeneration. Hum Mol Genet. 2017 Nov 14. doi: 10.1093/hmg/ddx400. [Epub ahead of print] PubMed PMID: 29145636. https://www.ncbi.nlm.nih.gov/pubmed/29145636?dopt=Abstract

4. Na CH, Barbhuiya M, Kim MS, Verbruggen S, Eacker S, Pletnikova O, Troncoso J, Halushka M, Menschaert G, Overall C, Pandey A. Discovery of non-canonical translation initiation sites through mass spectrometric analysis of protein N-termini. Genome Res. 2017 Nov 21. pii: gr.226050.117. doi: 10.1101/gr.226050.117. [Epub ahead of print] PubMed PMID: 29162641. https://www.ncbi.nlm.nih.gov/pubmed/29162641?dopt=Abstract

Nov 20 Pubcrawler Hits:

1. Karunakaran S, Clee SM. Genetics of metabolic syndrome: potential clues from wild-derived inbred mouse strains. Physiol Genomics. 2017 Nov 10:physiolgenomics.00059.2017. doi: 10.1152/physiolgenomics.00059.2017. [Epub ahead of print] PubMed PMID: 29127221. https://www.ncbi.nlm.nih.gov/pubmed/29127221?dopt=Abstract

2. Hawley AK, Nobu MK, Wright JJ, Durno WE, Morgan-Lang C, Sage B, Schwientek P, Swan BK, Rinke C, Torres-Beltrán M, Mewis K, Liu WT, Stepanauskas R, Woyke T, Hallam SJ. Diverse Marinimicrobia bacteria may mediate coupled biogeochemical cycles along eco-thermodynamic gradients. Nat Commun. 2017 Nov 15;8(1):1507. doi: 10.1038/s41467-017-01376-9. PubMed PMID: 29142241. https://www.ncbi.nlm.nih.gov/pubmed/29142241?dopt=Abstract

3. Sofer Y, Nevo N, Vechoropulus M, Shefer G, Osher E, Landis N, Hammond GL, Stern N. Human sex hormone binding globulin does not provide metabolic protection against dysglycemia in mice. Endocr Connect. 2017 Nov 15. pii: EC-17-0240. doi: 10.1530/EC-17-0240. [Epub ahead of print] PubMed PMID: 29141991. https://www.ncbi.nlm.nih.gov/pubmed/29141991?dopt=Abstract

4. Freitas-Andrade M, She J, Bechberger J, Naus CC, Sin WC. Acute connexin43 temporal and spatial expression in response to ischemic stroke. J Cell Commun Signal. 2017 Nov 13. doi: 10.1007/s12079-017-0430-6. [Epub ahead of print] PubMed PMID: 29134540. https://www.ncbi.nlm.nih.gov/pubmed/29134540?dopt=Abstract

5. Tsui CKM, Wong D, Narula G, Gardy JL, Hsiao WWH, Av-Gay Y. Genome Sequences of the Mycobacterium tuberculosis H37Rv-ptkA Deletion Mutant and Its Parental Strain. Genome Announc. 2017 Nov 2;5(44). pii: e01156-17. doi: 10.1128/genomeA.01156-17. PubMed PMID: 29097456; PubMed Central PMCID: PMC5668532. https://www.ncbi.nlm.nih.gov/pubmed/29097456?dopt=Abstract

Nov 13 Pubcrawler Hits:

1. Cao Y, Wang X, Shi X, Clee SM, McGeer PL, Wolf MO, Orvig C. Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes. Angew Chem Int Ed Engl. 2017 Oct 18. doi: 10.1002/anie.201708529. [Epub ahead of print] PubMed PMID: 29045760. https://www.ncbi.nlm.nih.gov/pubmed/29045760

2. Bowden CFM, Chan ACK, Li EJW, Arrieta AL, Eltis LD, Murphy MEP. Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin. J Biol Chem. 2017 Nov 6. pii: jbc.M117.806562. doi: 10.1074/jbc.M117.806562. [Epub ahead of print] PubMed PMID: 29109153. http://www.jbc.org/content/early/2017/11/06/jbc.M117.806562.abstract

3. Dou Y, Macdonald LC, Wu Y, Fedida D. The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues. Biophys J. 2017 Nov 7; 113(9):1979-1991. doi: 10.1016/j.bpj.2017.09.004. PubMed PMID: 29117522. http://www.sciencedirect.com/science/article/pii/S0006349517309906

4. Page MM, Skovsø S, Cen H, Chiu AP, Dionne DA, Hutchinson DF, Lim GE, Szabat M, Flibotte S, Sinha S, Nislow C, Rodrigues B, Johnson JD. Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain. FASEB J. 2017 Nov 9. pii: fj.201700518R. doi: 10.1096/fj.201700518R. [Epub ahead of print] PubMed PMID: 29122848. https://www.ncbi.nlm.nih.gov/pubmed/29122848

5. Lorincz MC, Schübeler D. Evidence for Converging DNA Methylation Pathways in Placenta and Cancer. Dev Cell. 2017 Nov 6; 43(3):257-258. doi: 10.1016/j.devcel.2017.10.009. PubMed PMID: 29112847. https://www.ncbi.nlm.nih.gov/pubmed/29112847

6. Osseman Q, Gallucci L, Au S, Cazenave C, Berdance E, Blondot ML, Cassany A, Bégu D, Ragues J, Aknin C, Sominskaya I, Dishlers A, Rabe B, Anderson F, Panté N, Kann M. The chaperone dynein LL1 mediates cytoplasmic transport of empty and mature hepatitis B virus capsids. J Hepatol. 2017 Nov 4. pii: S0168-8278(17)32424-8. doi: 10.1016/j.jhep.2017.10.032. [Epub ahead of print] PubMed PMID: 29113909. https://www.ncbi.nlm.nih.gov/pubmed/29113909/

7. Gale RT, Li FKK, Sun T, Strynadka NCJ, Brown ED. B. subtilis LytR-CpsA-Psr Enzymes Transfer Wall Teichoic Acids from Authentic Lipid-Linked Substrates to Mature Peptidoglycan In Vitro. Cell Chem Biol. 2017 Oct 12. pii: S2451-9456(17)30350-1. doi: 10.1016/j.chembiol.2017.09.006. [Epub ahead of print] PubMed PMID: 29107701. https://www.ncbi.nlm.nih.gov/pubmed/29107701?dopt=Abstract

Nov 6 Pubcrawler Hits: 

1. Law S, Panwar P, Li J, Aguda AH, Jamroz A, Guido RVC, Brömme D. A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K. PLoS One. 2017 Oct 31;12(10):e0186869. doi: 10.1371/journal.pone.0186869. eCollection 2017. PubMed PMID: 29088253. https://www.ncbi.nlm.nih.gov/pubmed/29088253

2. Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ. A compendium of geochemical information from the Saanich Inlet water column. Sci Data. 2017 Oct 31;4:170159. doi: 10.1038/sdata.2017.159. PubMed PMID: 29087371; PubMed Central PMCID: PMC5663218. https://www.nature.com/articles/sdata2017159

3. Hallam SJ, Torres-Beltrán M, Hawley AK. Monitoring microbial responses to ocean deoxygenation in a model oxygen minimum zone. Sci Data. 2017 Oct 31;4:170158. doi: 10.1038/sdata.2017.158. PubMed PMID: 29087370; PubMed Central PMCID: PMC5663219. https://www.ncbi.nlm.nih.gov/pubmed/29087370

4. Hawley AK, Torres-Beltrán M, Zaikova E, Walsh DA, Mueller A, Scofield M, Kheirandish S, Payne C, Pakhomova L, Bhatia M, Shevchuk O, Gies EA, Fairley D, Malfatti SA, Norbeck AD, Brewer HM, Pasa-Tolic L, Del Rio TG, Suttle CA, Tringe S, Hallam SJ. A compendium of multi-omic sequence information from the Saanich Inlet water column. Sci Data. 2017 Oct 31;4:170160. doi: 10.1038/sdata.2017.160. PubMed PMID: 29087368; PubMed Central PMCID: PMC5663217. https://www.nature.com/articles/sdata2017160

5. Au HHT, Elspass VM, Jan E. Functional insights into the adjacent stem-loop in honey bee dicistroviruses that promotes IRES-mediated translation and viral infection. J Virol. 2017 Nov 1. pii: JVI.01725-17. doi: 10.1128/JVI.01725-17. [Epub ahead of print] PubMed PMID: 29093099. http://jvi.asm.org/content/early/2017/10/26/JVI.01725-17.abstract

1. Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu T, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel M, Pilarski LM, Simpson EM, Lange P, Allan DW, Maxwell CA. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. Elife. 2017 Oct 10;6. pii: e28672. doi: 10.7554/eLife.28672. [Epub ahead of print] PubMed PMID:
28994651. https://www.ncbi.nlm.nih.gov/pubmed/28994651?report=&dispmax=200&tool=PubCrawler_1.2

2. Lu L, Hogan-Cann AD, Globa AK, Lu P, Nagy JI, Bamji SX, Anderson CM. Astrocytes drive cortical vasodilatory signaling by activating endothelial NMDA receptors. J Cereb Blood Flow Metab. 2017 Jan 1:271678X17734100. doi: 10.1177/0271678X17734100. [Epub ahead of print] PubMed PMID: 29072857. https://www.ncbi.nlm.nih.gov/pubmed/29072857

3. Carrel L, Brown CJ. When the Lyon(ized chromosome) roars: ongoing expression from an inactive X chromosome. Philos Trans R Soc Lond B Biol Sci. 2017 Nov 5;372(1733). pii: 20160355. doi: 10.1098/rstb.2016.0355. Review. PubMed PMID: 28947654; PubMed Central PMCID: PMC5627157. https://www.ncbi.nlm.nih.gov/pubmed/28947654

4. Pang SS, Wijeyewickrema LC, Hor L, Tan S, Lameignere E, Conway EM, Blom AM, Mohlin FC, Liu X, Payne RJ, Whisstock JC, Pike RN. The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech. J Immunol. 2017 Oct 23. pii: ji1700158. doi: 10.4049/jimmunol.1700158. [Epub ahead of print] PubMed PMID: 29061764.  https://www.ncbi.nlm.nih.gov/pubmed/29061764

5. Crowe SA, Treusch AH, Forth M, Li J, Magen C, Canfield DE, Thamdrup B, Katsev S. Novel anammox bacteria and nitrogen loss from Lake Superior. Sci Rep. 2017 Oct 23; 7(1):13757. doi: 10.1038/s41598-017-12270-1. PubMed PMID: 29061974; PubMed Central PMCID: PMC5653767. https://www.nature.com/articles/s41598-017-12270-1

6. Neumann UH, Ho JSS, Chen S, Tam YYC, Cullis PR, Kieffer TJ. Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes. Mol Metab. 2017 Oct;6(10):1161-1172. doi: 10.1016/j.molmet.2017.06.012. Epub 2017 Jun 22. PubMed PMID: 29031717. https://www.ncbi.nlm.nih.gov/pubmed/29031717?dopt=Abstract

7. Nassif ME, Tang Y, Cleland JG, Abraham WT, Linde C, Gold MR, Young JB, Daubert JC, Sherfesee L, Schaber D, Tang ASL, Jones PG, Arnold SV, Spertus JA. Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials. Circ Heart Fail. 2017 Oct;10(10). pii: e004111. doi: 10.1161/CIRCHEARTFAILURE.117.004111. PubMed PMID: 29038172. https://www.ncbi.nlm.nih.gov/pubmed/29038172?dopt=Abstract

8. Strassert JFH, Karnkowska A, Hehenberger E, Del Campo J, Kolisko M, Okamoto N, Burki F, Janouškovec J, Poirier C, Leonard G, Hallam SJ, Richards TA, Worden AZ, Santoro AE, Keeling PJ. Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates. ISME J. 2017 Oct 10. doi: 10.1038/ismej.2017.167. [Epub ahead of print] PubMed PMID: 28994824.
https://www.ncbi.nlm.nih.gov/pubmed/28994824?report=&dispmax=200&tool=PubCrawler_1.2

9. Saez-Lopez C, Brianso-Llort L, Torres-Torrenteras J, Simó R, Hammond GL, Selva DM. Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox. Sci Rep. 2017 Sep 25;7(1):12284. doi: 10.1038/s41598-017-12509-x. PubMed PMID: 28947831; PubMed Central PMCID: PMC5612985. https://www.nature.com/articles/s41598-017-12509-x

10. Morse ZJ, Horwitz MS. Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset. Front Endocrinol (Lausanne). 2017 Sep 26;8:249. doi: 10.3389/fendo.2017.00249. eCollection 2017. Review. PubMed PMID: 29018409; PubMed
Central PMCID: PMC5623193. https://www.ncbi.nlm.nih.gov/pubmed/29018409?report=&dispmax=200&tool=PubCrawler_1.2

11. Mouat IC, Morse ZJ, Jean-Baptiste VSE, Allanach JR, Horwitz MS. Fresh Ideas, Foundational Experiments (FIFE): Immunology and Diabetes 2016 FIFE Symposium. Front Endocrinol (Lausanne). 2017 Sep 19;8:238. doi: 10.3389/fendo.2017.00238.
eCollection 2017. PubMed PMID: 28974943; PubMed Central PMCID: PMC5610696. https://www.ncbi.nlm.nih.gov/pubmed/28974943

12. Ramzy A, Mojibian M, Kieffer TJ. Insulin deficient mouse β-cells do not fully mature but can be remedied through insulin replacement by islet transplantation. Endocrinology. 2017 Sep 27. doi: 10.1210/en.2017-00263. [Epub ahead of print] PubMed PMID:  29029025. https://www.ncbi.nlm.nih.gov/pubmed/29029025?dopt=Abstract

13. Kieffer TJ. In Memoriam-John C. Brown, PhD, DSc, FRSC, 1938-2016: Discoverer of GIP and Motilin. Gastroenterology. 2017 Oct 5. pii: S0016-5085(17)36196-6. doi: 10.1053/j.gastro.2017.09.037. [Epub ahead of print] PubMed PMID: 28988915. http://metcorner.gastro.org/article/S0016-5085(17)36196-6/fulltext

14. Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N. Beta cell replacement strategies for diabetes. J Diabetes Investig. 2017 Oct 6. doi: 10.1111/jdi.12758. [Epub ahead of print] PubMed PMID: 28984038. https://www.ncbi.nlm.nih.gov/pubmed/28984038

15. D'souza AM, Neumann UH, Glavas MM, Kieffer TJ. The glucoregulatory actions of leptin. Mol Metab. 2017 May 4;6(9):1052-1065. doi: 10.1016/j.molmet.2017.04.011. eCollection 2017 Sep. Review. PubMed PMID: 28951828; PubMed Central PMCID:
PMC5605734. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605734/

16. Kumar P, Takayesu A, Abbasi U, Kalathottukaren MT, Abbina S, Kizhakkedathu JN, Straus SK. Antimicrobial Peptide-Polymer Conjugates with High Activity: Influence of Polymer Molecular Weight and Peptide Sequence on Antimicrobial Activity,
Proteolysis, and Biocompatibility. ACS Appl Mater Interfaces. 2017 Oct 19. doi: 10.1021/acsami.7b09471. [Epub ahead of print] PubMed PMID: 29019386. https://www.ncbi.nlm.nih.gov/pubmed/29019386?dopt=Abstract

17. Hadjesfandiari N, Weinhart M, Kizhakkedathu JN, Haag R, Brooks DE. Development of Antifouling and Bactericidal Coatings for Platelet Storage Bags Using Dopamine Chemistry. Adv Healthc Mater. 2017 Sep 29. doi: 10.1002/adhm.201700839. [Epub ahead of print] PubMed PMID: 28961393. https://www.ncbi.nlm.nih.gov/pubmed/28961393

18. Mathew V, Tam AS, Milbury KL, Hofmann AK, Hughes CS, Morin GB, Loewen CJR, Stirling PC. Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress. J Cell Biol. 2017 Oct 4. pii: jcb.201612018. doi: 10.1083/jcb.201612018. [Epub ahead of print] PubMed PMID: 28978642. https://www.ncbi.nlm.nih.gov/pubmed/28978642

19. Paik YK, Omenn GS, Lane L, Overall CM. Advances in the Chromosome-Centric Human Proteome Project: Looking to the Future. Expert Rev Proteomics. 2017 Oct 17. doi: 10.1080/14789450.2017.1394189. [Epub ahead of print] PubMed PMID:  29039980. https://www.ncbi.nlm.nih.gov/pubmed/29039980?dopt=Abstract

20. Schwenk JM, Omenn GS, Sun Z, Campbell DS, Baker MS, Overall CM, Aebersold R, Moritz RL, Deutsch EW. The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays. J Proteome Res. 2017 Oct 10. doi: 10.1021/acs.jproteome.7b00467. [Epub ahead of print] PubMed PMID: 28938075.
https://www.ncbi.nlm.nih.gov/pubmed/28938075?report=&dispmax=200&tool=PubCrawler_1.2

21. Paik YK, Omenn GS, Lane L, Overall CM. Advances in the Chromosome-Centric Human Proteome Project: Looking to the Future. Expert Rev Proteomics. 2017 Oct 17. doi: 10.1080/14789450.2017.1394189. [Epub ahead of print] PubMed PMID: 29039980. https://www.ncbi.nlm.nih.gov/pubmed/29039980

22. Chu TLH, Connell M, Zhou L, He Z, Won JR, Rahavi SM, Chen H, Mohan P, Nemirovsky O, Fotovati A, Pujana MA, Reid GS, Nielsen TO, Pante N, Maxwell CA. Cell Cycle-dependent Tumor Engraftment and Migration are Enabled by Aurora A. Mol Cancer Res. 2017 Oct 9. pii: molcanres.0417.2017. doi: 10.1158/1541-7786.MCR-17-0417. [Epub ahead of print] PubMed PMID: 28993511.
https://www.ncbi.nlm.nih.gov/pubmed/28993511?report=&dispmax=200&tool=PubCrawler_1.2

23. Bernardes NE, Takeda AAS, Dreyer TR, Cupertino FB, Virgilio S, Pante N, Bertolini MC, Fontes MRM. Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by Importin-α. Biochem J. 2017 Oct 20. pii: BCJ20170654. doi: 10.1042/BCJ20170654. [Epub ahead of print] PubMed PMID: 29054975. https://www.ncbi.nlm.nih.gov/pubmed/29054975

24. Fairchild MJ, Islam F, Tanentzapf G. Identification of genetic networks that act in the somatic cells of the testis to mediate the developmental program of spermatogenesis. PLoS Genet. 2017 Sep 28;13(9):e1007026. doi: 10.1371/journal.pgen.1007026. eCollection 2017 Sep. PubMed PMID: 28957323; PubMed Central PMCID: PMC5634645. http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007026

25. Liu Y, Wei J, Wong King Yuen SM, Sun B, Tang Y, Wang R, Van Petegem F, Chen SRW. CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression. PLoS One. 2017 Sep 29; 12(9):e0184177. doi: 10.1371/journal.pone.0184177.  eCollection 2017. PubMed PMID: 28961276; PubMed Central PMCID: PMC5621672. https://www.ncbi.nlm.nih.gov/pubmed/28961276

26. Wong King Yuen SM, Campiglio M, Tung CC, Flucher BE, Van Petegem F. Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc Natl Acad Sci U S A. 2017 Oct 23. pii: 201708852. doi: 10.1073/pnas.1708852114. [Epub ahead of print] PubMed PMID: 29078335. https://www.ncbi.nlm.nih.gov/pubmed/29078335

27. Vogl WA, Lyon K, Adams A, Piva M, Nassour V. The endoplasmic reticulum, calcium signaling and junction turnover in Sertoli cells. Reproduction. 2017 Oct 24. pii: REP-17-0281. doi: 10.1530/REP-17-0281. [Epub ahead of print] PubMed PMID: 29066527. https://www.ncbi.nlm.nih.gov/pubmed/29066527

28. Lillie MA, Vogl WA, Raverty S, Haulena M, McLellan WA, Stenson GB, Shadwick RE. Controlling thoracic pressures in cetaceans during a breath-hold dive: importance of the diaphragm. J Exp Biol. 2017 Oct 1;220(Pt 19):3464-3477. doi: 10.1242/jeb.162289. PubMed PMID: 28978638. https://www.ncbi.nlm.nih.gov/pubmed/28978638

29. Vogl WA, Petersen H, Adams A, Lillie MA, Shadwick RE. The Functional Anatomy of Nerves Innervating the Ventral Grooved Blubber of Fin Whales (Balaenoptera Physalus). Anat Rec (Hoboken). 2017 Nov; 300(11):1963-1972. doi: 10.1002/ar.23649. PubMed PMID: 28971627. https://www.ncbi.nlm.nih.gov/pubmed/28971627

30. Vogl WA "Welcoming" Introduction to a Canadian Northwest Coast Thematic Papers Issue. Anat Rec (Hoboken). 2017 Nov; 300(11):1930-1934. doi: 10.1002/ar.23675. PubMed PMID: 28971625. https://www.ncbi.nlm.nih.gov/pubmed/28971625

31. Nanji T, Liu X, Chew LH, Li FK, Biswas M, Yu ZQ, Lu S, Dong MQ, Du LL, Klionsky DJ, Yip CK. Conserved and unique features of the fission yeast core Atg1 complex. Autophagy. 2017 Oct 4:0. doi: 10.1080/15548627.2017.1382782. [Epub ahead
of print] PubMed PMID: 28976798. https://www.ncbi.nlm.nih.gov/pubmed/28976798

*Accessed weekly through Pubcrawler: http://pubcrawler.gen.tcd.ie/cgi-bin/pubcrawler_www.pl