LSI Pub Corner

LSI Pub Corner

Find the latest publications from LSI’s researchers here:


Aug 19, Pubcrawler Hits:

1. Marshall EA, Stewart GL, Sage AP, Lam WL, Brown CJ. Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge. PLoS One. 2019 Aug 16;14(8):e0221371. doi: 10.1371/journal.pone.0221371. eCollection 2019. PubMed PMID: 31419261.

2. Kulkarni JA, Witzigmann D, Chen S, Cullis PR, van der Meel R. Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics. Acc Chem Res. 2019 Aug 9. doi: 10.1021/acs.accounts.9b00368. [Epub ahead of print] PubMed PMID: 31397996.

3. Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV. Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood. Transfusion. 2019 Aug 13. doi: 10.1111/trf.15485. [Epub ahead of print] PubMed PMID: 31408208.

4. Hanson PJ, Hossain AR, Qiu Y, Zhang HM, Zhao G, Li C, Lin V, Sulaimon S, Vlok M, Fung G, Chen VH, Jan E, McManus BM, Granville DJ, Yang D. Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection. Front Cell Infect Microbiol. 2019 Jul 24;9:265. doi: 10.3389/fcimb.2019.00265. eCollection 2019. PubMed PMID: 31396490; PubMed Central PMCID: PMC6667557.

5. Shi H, Strogantsev R, Takahashi N, Kazachenka A, Lorincz MC, Hemberger M, Ferguson-Smith AC. ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains. Epigenetics Chromatin. 2019 Aug 9; 12(1):49. doi: 10.1186/s13072-019-0295-4. PubMed PMID: 31399135; PubMed Central PMCID: PMC6688207.

6. Dyka FM, Molday LL, Chiodo V, Molday RS, Hauswirth WW. Dual ABCA4-AAV vector treatment reduces pathogenic retinal A2E accumulation in a mouse model of autosomal recessive Stargardt Disease. Hum Gene Ther. 2019 Aug 16. doi: 10.1089/hum.2019.132. [Epub ahead of print] PubMed PMID: 31418294.

7. Choi H, Andersen JP, Molday RS. Expression and Functional Characterization of Missense Mutations in ATP8A2 Linked to Severe Neurological Disorders. Hum Mutat. 2019 Aug 9. doi: 10.1002/humu.23889. [Epub ahead of print] PubMed PMID: 31397519.

5. Mellor GJ, Panwar P, Lee AK, Steinberg C, Hathaway JA, Bartels K, Christian S, Balaji S, Roberts JD, Simpson CS, Boczek NJ, Tester DJ, Radbill AE, Mok NS, Hamilton RM, Kaufman ES, Eugenio PL, Weiss R, January C, McDaniel GM, Leather RA, Erickson C, Falik S, Behr ER, Wilde AAM, Sanatani S, Ackerman MJ, Van Petegem F, Krahn AD, Laksman Z. Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site. Europace. 2019 Aug pii: euz215. doi: 10.1093/europace/euz215. [Epub ahead of print] PubMed PMID: 31408100.

6. Kwan JZJ, Nguyen TF, Teves SS. Visualizing Transcription Factor Binding on Mitotic Chromosomes Using Single-Molecule Live-Cell Imaging. Methods Mol Biol. 2019; 2038:239-250. doi: 10.1007/978-1-4939-9674-2_16. PubMed PMID: 31407289.

Aug 12, Pubcrawler Hits:

1. Devine DV. Ironing out frequent blood donation. Lancet Haematol. 2019 Aug 2. pii: S2352-3026(19)30162-0. doi: 10.1016/S2352-3026(19)30162-0. [Epub ahead of print] PubMed PMID: 31383582.

2. Zhang AMY, Magrill J, de Winter TJJ, Hu X, Skovsø S, Schaeffer DF, Kopp JL, Johnson JD. Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development. Cell Metab. 2019 Jul 23. pii: S1550-4131(19)30376-6. doi: 10.1016/j.cmet.2019.07.003. [Epub ahead of print] PubMed PMID: 31378465.

3. Zelanis A, Oliveira AK, Prudova A, Huesgen PF, Tashima AK, Kizhakkedathu J, Overall CM, Serrano SMT. Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Substrates (TAILS) N-Terminomics. J Proteome Res. 2019 Aug 8. doi: 10.1021/acs.jproteome.9b00325. [Epub ahead of print] PubMed PMID: 31337208.

4. Tadini-Buoninsegni F, Mikkelsen SA, Mogensen LS, Molday RS, Andersen JP. Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic. Proc Natl Acad Sci U S A. 2019 Aug 1. pii: 201910211. doi: 10.1073/pnas.1910211116. [Epub ahead of print] PubMed PMID: 31371510.

Aug 5, Pubcrawler Hits:

1. Carlson ML, Stacey RG, Young JW, Wason IS, Zhao Z, Rattray DG, Scott N, Kerr CH, Babu M, Foster LJ, Duong FVH. Profiling the E. coli membrane interactome captured in peptidisc libraries. Elife. 2019 Jul 31;8. pii: e46615. doi: 10.7554/eLife.46615. [Epub ahead of print] PubMed PMID: 31364989.

2. Heinkel F, Abraham L, Ko M, Chao J, Bach H, Hui LT, Li H, Zhu M, Ling YM, Rogalski JC, Scurll J, Bui JM, Mayor T, Gold MR, Chou KC, Av-Gay Y, McIntosh LP, Gsponer J. Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2019 Jul 31. pii: 201820683. doi:10.1073/pnas.1820683116. [Epub ahead of print] PubMed PMID: 31366629.

3. Tudurí E, Glavas MM, Asadi A, Baker RK, Ellis CE, Soukhatcheva G, Philit M, Huynh FK, Johnson JD, Bruce Verchere C, Kieffer TJ. AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells. Sci Rep. 2019 Jul 25;9(1):10829. doi: 10.1038/s41598-019-46735-2. PubMed PMID: 31346189; PubMed Central PMCID: PMC6658537.

4. Cembrowski MS. Single-cell transcriptomics as a framework and roadmap for understanding the brain. J Neurosci Methods. 2019 Jul 25;326:108353. doi: 10.1016/j.jneumeth.2019.108353. [Epub ahead of print] Review. PubMed PMID: 31351971.

Jul 29, Pubcrawler Hits:

1. Jobin PG, Solis N, Machado Y, Bell PA, Kwon NH, Kim S, Overall CM, Butler GS. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019 Jul 19. pii: jbc.RA119.009584. doi: 10.1074/jbc.RA119.009584. [Epub ahead of print] PubMed PMID: 31324718.

Jul 22, Pubcrawler Hits:

1. Musso PY, Junca P, Jelen M, Feldman-Kiss D, Zhang H, Chan RC, Gordon MD. Closed-loop optogenetic activation of peripheral or central neurons modulates feeding in freely moving Drosophila. Elife. 2019 Jul 19;8. pii: e45636. doi: 10.7554/eLife.45636. [Epub ahead of print] PubMed PMID: 31322499.

2. Hill L, Sumer-Bayraktar Z, Lewis JG, Morava E, Thaysen-Andersen M, Hammond GL. N-Glycosylation influences human corticosteroid-binding globulin measurements. Endocr Connect. 2019 Jul 1. pii: EC-19-0242.R1. doi: 10.1530/EC-19-0242. [Epub ahead of print] PubMed PMID: 31307013.

Jul 15, Pubcrawler Hits:

1. Andrault PM, Panwar P, Mackenzie NCW, Brömme D. Elastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification. Sci Rep. 2019 Jul 4;9(1):9682. doi: 0.1038/s41598-019-45918-1. PubMed PMID: 31273243; PubMed Central PMCID: PMC6609650.

2. Ozaki K, Thompson KJ, Simister RL, Crowe SA, Reinhard CT. Anoxygenic photosynthesis and the delayed oxygenation of Earth's atmosphere. Nat Commun. 2019 Jul 9;10(1):3026. doi: 10.1038/s41467-019-10872-z. PubMed PMID: 31289261; PubMed Central PMCID: PMC6616575.

3. Kuatsjah E, Verstraete MM, Kobylarz MJ, Liu AKN, Murphy MEP, Eltis LD. Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. J Biol Chem. 2019 Jul 10. pii: jbc.RA119.009428. doi: 10.1074/jbc.RA119.009428. [Epub ahead of print] PubMed PMID: 31292192.

4. Cait A, Cardenas E, Dimitriu P, Amenyogbe N, Dai D, Cait J, Sbihi H, Stiemsma L, Subbarao P, Mandhane PJ, Becker AB, Moraes TJ, Sears MR, Lefebvre DL, Azad MB, Kollmann T, Turvey SE, Mohn WW. Reduced genetic potential for butyrate fermentation in the gut microbiome of infants who develop allergic sensitization. J Allergy Clin Immunol. 2019 Jul 3. pii: S0091-6749(19)30891-7. doi: 10.1016/j.jaci.2019.06.029. [Epub ahead of print] PubMed PMID: 31279007.

5. Khater IM, Liu Q, Chou KC, Hamarneh G, Nabi IR. Super-resolution modularity analysis shows polyhedral caveolin-1 oligomers combine to form scaffolds and caveolae. Sci Rep. 2019 Jul 8;9(1):9888. doi: 10.1038/s41598-019-46174-z. PubMed PMID: 31285524.

6. Adams A, Yoo KM, Vogl W. Lipid transfer machinery is present at membrane contact sites associated with the internalization of junctions in Sertoli cells. Biol Reprod. 2019 Jul 11. pii: ioz120. doi: 10.1093/biolre/ioz120. [Epub ahead of print] PubMed PMID: 31292601.

Jul 8, Pubcrawler Hits:

1. Petrus P, Fernandez TL, Kwon MM, Huang JL, Lei V, Safikhan NS, Karunakaran S, O'Shannessy DJ, Zheng X, Catrina SB, Albone E, Laine J, Virtanen K, Clee SM, Kieffer TJ, Noll C, Carpentier AC, Johnson JD, Rydén M, Conway EM. Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation. EBioMedicine. 2019 Jun;44:489-501. doi: 10.1016/j.ebiom.2019.05.057. Epub 2019 Jun 17. PubMed PMID: 31221584.

2. Farr Zuend C, Nomellini JF, Smit J, Horwitz MS. A Caulobacter crescentus microbicide protects from vaginal infection with HIV-1(JR-CSF) in Humanized Bone Marrow-Liver-Thymus Mice. J Virol. 2019 Jun 26. pii: JVI.00614-19. doi: 10.1128/JVI.00614-19. [Epub ahead of print] PubMed PMID: 31243127.

Jul 1, Pubcrawler Hits:

1. Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, László V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szűcs M, Kuba K, Dome B, Cao Y, Haubner BJ, Penninger JM. Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy. EMBO Mol Med. 2019 Jun 24:e9266. doi: 10.15252/emmm.201809266. [Epub ahead of print] PubMed PMID: 31267692.

Jun 17, Pubcrawler Hits:

1. Shah BS, Shimell JJ, Bamji SX. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J Cell Sci. 2019 Jun 12. pii: jcs.230052. doi: 10.1242/jcs.230052. [Epub ahead of print] PubMed PMID: 31189538.

2. Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG. An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nat Microbiol. 2019 Jun 10. doi: 10.1038/s41564-019-0469-7. [Epub ahead of print] PubMed PMID: 31182795.

3. Bomkamp C, Padmanabhan N, Karimi B, Ge Y, Chao JT, Loewen CJR, Siddiqui TJ, Craig AM. Mechanisms of PTPσ-Mediated Presynaptic Differentiation. Front Synaptic Neurosci. 2019 May 22;11:17. doi: 10.3389/fnsyn.2019.00017. eCollection 2019. PubMed PMID: 31191292; PubMed Central PMCID: PMC6540616.

4. Verstraete MM, Morales LD, Kobylarz MJ, Loutet SA, Laakso HA, Pinter TB, Stillman MJ, Heinrichs DE, Murphy MEP. The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus. J Biol Chem. 2019 Jun 13. pii: jbc.RA119.007757. doi: 10.1074/jbc.RA119.007757. [Epub ahead of print] PubMed PMID: 31197035.

5. Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GY. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proc Natl Acad Sci U S A. 2019 Jun 12. pii: 201900152. doi: 10.1073/pnas.1900152116. [Epub ahead of print] PubMed PMID: 31189595.

Jun 10, Pubcrawler Hits:

1. Bolger-Munro M, Choi K, Scurll JM, Abraham L, Chappell RS, Sheen D, Dang-Lawson M, Wu X, Priatel JJ, Coombs D, Hammer JA, Gold MR. Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and cell activation. Elife. 2019 Jun 3;8. pii: e44574. doi: 10.7554/eLife.44574. [Epub ahead of print] PubMed PMID: 31157616.

2. Armstrong Z, Liu F, Kheirandish S, Chen HM, Mewis K, Duo T, Morgan-Lang C, Hallam SJ, Withers SG. High-Throughput Recovery and Characterization of Metagenome-Derived Glycoside Hydrolase-Containing Clones as a Resource for Biocatalyst Development. mSystems. 2019 Jun 4;4(4). pii: e00082-19. doi: 10.1128/mSystems.00082-19. PubMed PMID: 31164449.

3. Spanier JA, Tse HM, Horwitz MS, Fife BT. Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes. Front Endocrinol (Lausanne). 2019 May 16;10:315. doi: 10.3389/fendo.2019.00315. eCollection 2019. PubMed PMID: 31156560; PubMed Central PMCID: PMC6532014.

4. Warsaba R, Sadasivan J, Jan E. Dicistrovirus-Host Molecular Interactions. Curr Issues Mol Biol. 2019 Jun 6;34:83-112. doi: 10.21775/cimb.034.083. [Epub ahead of print] PubMed PMID: 31167957.

5. Chopra S, Overall CM, Dufour A. Matrix metalloproteinases in the CNS: interferons get nervous. Cell Mol Life Sci. 2019 Jun 4. doi: 10.1007/s00018-019-03171-9. [Epub ahead of print] Review. PubMed PMID: 31165203.

6. Elling U, Woods M, Forment JV, Fu B, Yang F, Ng BL, Vicente JR, Adams DJ, Doe B, Jackson SP, Penninger JM, Balmus G. Derivation and maintenance of mouse haploid embryonic stem cells. Nat Protoc. 2019 Jun 3. doi: 10.1038/s41596-019-0169-z. [Epub ahead of print] PubMed PMID: 31160788.

Jun 03, Pubcrawler Hits:

1. Abbina S, Abbasi U, Gill A, Wong K, Kalathottukaren MT, Kizhakkedathu JN. Design of Safe Nanotherapeutics for the Excretion of Excess Systemic Toxic Iron. ACS Cent Sci. 2019 May 22;5(5):917-926. doi: 10.1021/acscentsci.9b00284. Epub 2019 Apr 11. PubMed PMID: 31139728; PubMed Central PMCID: PMC6535967.

2. Reina J, Zhou L, M Fontes MR, Panté N, Cella N. Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation. FEBS Open Bio. 2019 Mar 20. doi: 10.1002/2211-5463.12626. [Epub ahead of print] PubMed PMID: 31144423.

3. Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A, Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N, Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ, She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K, Kroemer G, Penninger JM. AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Res. 2019 May 27. doi: 10.1038/s41422-019-0181-4. [Epub ahead of print] PubMed PMID: 31133695.

May 27, Pubcrawler Hits:

1. Louca S, Scranton MI, Taylor GT, Astor YM, Crowe SA, Doebeli M. Circumventing kinetics in biogeochemical modeling. Proc Natl Acad Sci U S A. 2019 May 16. pii: doi: 10.1073/pnas.1819883116. [Epub ahead of print] PubMed PMID:

2. Jyotsana N, Sharma A, Chaturvedi A, Budida R, Scherr M, Kuchenbauer F, Lindner R, Noyan F, Sühs KW, Stangel M, Grote-Koska D, Brand K, Vornlocher HP, Eder M, Thol F, Ganser A, Humphries RK, Ramsay E, Cullis P, Heuser M. Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. Ann Hematol. 2019 May 18. doi: 10.1007/s00277-019-03713-y. [Epub ahead of print] PubMed PMID: 31104089.

3. Senini V, Amara U, Paul M, Kim H. Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis. J Periodontol. 2019 May 20. doi: 10.1002/JPER.18-0596. [Epub ahead of print] PubMed PMID: 31106406.

4. Liu B, Feng S, Dairi G, Guan Q, Chafeeva I, Wang H, Liggins R, da Roza G, Kizhakkedathu JN, Du C. Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution. BMC Nephrol. 2019 May 21; 20(1) :181. doi: 10.1186/s12882-019-1376-0. PubMed PMID: 31113397.

5. Mothersole RG, MacDonald M, Kolesnikov M, Murphy MEP, Wolthers KR. Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin. Protein Sci. 2019 May 22. doi: 10.1002/pro.3661. [Epub ahead of print] PubMed PMID: 31116469.

6. Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M. The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. PLoS One. 2019 May 23;14(5):e0216423. doi: 10.1371/journal.pone.0216423. eCollection 2019. PubMed PMID: 31120902.

7. Rabea SM, Baradaran-Heravi A, Balgi AD, Krause A, Hosseini Farahabadi S, Roberge M, Grierson DS. 2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides. ACS Med Chem Lett. 2019 Apr 9;10(5):726-731. doi: 10.1021/ acsmedchemlett.8b00610. eCollection 2019 May 9. PubMed PMID: 31097990; PubMed Central PMCID: PMC6511968.

8. Raineki C, Morgan EJ, Ellis L, Weinberg J. Glucocorticoid receptor expression in the stress-limbic circuitry is differentially affected by prenatal alcohol exposure and adolescent stress. Brain Res. 2019 May 15. pii: S0006-8993(19)30274-4. doi: 10.1016/j.brainres.2019.05.019. [Epub ahead of print] PubMed PMID: 31102593.

May 20, Pubcrawler Hits:

1. Macdonald SS, Armstrong Z, Morgan-Lang C, Osowiecka M, Robinson K, Hallam SJ, Withers SG. Development and Application of a High-Throughput Functional Metagenomic Screen for Glycoside Phosphorylases. Cell Chem Biol. 2019 May 9. pii: S2451-9456(19)30113-8. doi: 10.1016/j.chembiol.2019.03.017. [Epub ahead of print] PubMed PMID: 31080075.

2. Lau GY, Barts N, Hartley RC, Tobler M, Richards JG, Murphy MP, Arndt S. Detection of changes in mitochondrial hydrogen sulfide in vivo in the fish model Poecilia mexicana (Poeciliidae). Biol Open. 2019 May 9;8(5). pii: bio041467. doi: 10.1242/bio.041467. PubMed PMID: 31072908.

3. Gardill BR, Rivera-Acevedo RE, Tung CC, Van Petegem F. Crystal structures of Ca(2+)-calmodulin bound to Na(V) C-terminal regions suggest role for EF-hand domain in binding and inactivation. Proc Natl Acad Sci U S A. 2019 May 9. pii: 201818618. doi: 10.1073/pnas.1818618116. [Epub ahead of print] PubMed PMID: 31072926.

4. Katsube M, Rolfe SM, Bortolussi SR, Yamaguchi Y, Richman JM, Yamada S, Vora SR. Analysis of facial skeletal asymmetry during foetal development using μCT imaging. Orthod Craniofac Res. 2019 May;22 Suppl 1:199-206. doi: 10.1111/ocr.12304. PubMed PMID: 31074127; PubMed Central PMCID: PMC6512839.

5. McSwiggen DT, Hansen AS, Teves SS, Marie-Nelly H, Hao Y, Heckert AB, Umemoto KK, Dugast-Darzacq C, Tjian R, Darzacq X. Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. Elife. 2019 May 7;8. pii: e47098. doi: 10.7554/eLife.47098. PubMed PMID: 31038454.

May 13, Pubcrawler Hits:

1. Frirdich E, Biboy J, Pryjma M, Lee J, Huynh S, Parker CT, Girardin SE, Vollmer W, Gaynor EC. The Campylobacter jejuni helical to coccoid transition involves changes to peptidoglycan and the ability to elicit an immune response. Mol Microbiol. 2019 May 9. doi: 10.1111/mmi.14269. [Epub ahead of print] PubMed PMID: 31070821.

2. Ehrhardt K, Steck N, Kappelhoff R, Stein S, Rieder F, Gordon IO, Boyle EC, Braubach P, Overall CM, Finlay BB, Grassl GA. Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis. Inflamm Bowel Dis. 2019 May 9. pii: izz070. doi: 10.1093/ibd/izz070. [Epub ahead of print] PubMed PMID: 31066456.

3. Haji-Ghassemi O, Yuchi Z, Van Petegem F. The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner. Mol Cell. Published: May 08, 2019DOI:

4. Tamura K, Foley MH, Gardill BR, Dejean G, Schnizlein M, Bahr CME, Louise Creagh A, van Petegem F, Koropatkin NM, Brumer H. Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cell Mol Life Sci. 2019 May 6. doi: 10.1007/s00018-019-03115-3. [Epub ahead of print] PubMed PMID: 31062073.

5. Caveney NA, Pavlin A, Caballero G, Bahun M, Hodnik V, de Castro L, Fornelos N, Butala M, Strynadka NCJ. Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure. 2019 Apr 10. pii: S0969-2126(19)30115-7. doi: 10.1016/j.str.2019.03.019. [Epub ahead of print] PubMed PMID: 31056420.

May 06, Pubcrawler Hits:

1. Gold MR, Reth MG. Antigen Receptor Function in the Context of the Nanoscale Organization of the B Cell Membrane. Annu Rev Immunol. 2019 Apr 26;37:97-123. doi: 10.1146/annurev-immunol-042718-041704. PubMed PMID: 31026412.

2. Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, Liu C, Walker CL, Jonasch E, Lefebvre L, Wu M, Lorincz MC, Li W, Li L, Xie W. SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development. Nat Genet. 2019 May;51(5):844-856. doi: 10.1038/s41588-019-0398-7. Epub 2019 Apr 29. PubMed PMID: 31040401.

3. Hendi A, Kurashina M, Mizumoto K. Intrinsic and extrinsic mechanisms of synapse formation and specificity in C. elegans. Cell Mol Life Sci. 2019 Apr 29. doi: 10.1007/s00018-019-03109-1. [Epub ahead of print] Review.

4. Gignac SJ, Hosseini-Farahabadi S, Akazawa T, Schuck NJ, Fu K, Richman JM. Robinow syndrome skeletal phenotypes caused by the WNT5AC83S variant are due to dominant interference with chondrogenesis. Hum Mol Genet. 2019 Apr 3. pii: ddz071. doi: 10.1093/hmg/ddz071. [Epub ahead of print] PubMed PMID: 31032853.

April 29, Pubcrawler Hits:

1. Conway EM. Polyphosphates and Complement Activation. Front Med (Lausanne). 2019 Apr 4;6:67. doi: 10.3389/fmed.2019.00067. eCollection 2019. Review. PubMed PMID: 31019911; PubMed Central PMCID: PMC6458250.

2. Kulkarni JA, Witzigmann D, Leung J, van der Meel R, Zaifman J, Darjuan MM, Grisch-Chan HM, Thöny B, Tam YYC, Cullis PR. Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads. Nanoscale. 2019 Apr 25. doi: 10.1039/c9nr02004g. [Epub ahead of print] PubMed PMID: 31021343.

3. Caveney NA, Caballero G, Voedts H, Niciforovic A, Worrall LJ, Vuckovic M, Fonvielle M, Hugonnet JE, Arthur M, Strynadka NCJ. Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun. 2019 Apr 23;10(1):1849. doi: 10.1038/s41467-019-09507-0. PubMed PMID: 31015395; PubMed Central PMCID: PMC6478713.

April 23, Pubcrawler Hits:

1. Kaner Z, Engelman R, Schuster R, Rider P, Greenberg D, Av-Gay Y, Benhar M, Lewis EC. S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination. Front Immunol. 2019 Apr 2;10:590. doi: 10.3389/fimmu.2019.00590. eCollection 2019. PubMed PMID: 31001247; PubMed Central PMCID: PMC6454134.

2. Geletu M, Taha Z, Arulanandam R, Mohan R, Assi HH, Castro MG, Nabi IR, Gunning PT, Raptis L PhD. Effect of Caveolin-1 upon Stat3-ptyr705 levels in breast and lung carcinoma cells. Biochem Cell Biol. 2019 Apr 15. doi: 10.1139/bcb-2018-0367. [Epub ahead of print] PubMed PMID: 30986357.

3. Trudel D, Avarvarei LM, Orain M, Turcotte S, Plante M, Grégoire J, Kappelhoff  R, Labbé DP, Bachvarov D, Têtu B, Overall CM, Bairati I. Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer. Pathol Res Pract. 2019 Mar 2. pii: S0344-0338(18)31674-1. doi: 10.1016/j.prp.2019.02.019. [Epub ahead of print] PubMed PMID: 30987833.

4. Paik YK, Overall CM, Corrales F, Deutsch EW, Lane L, Omenn GS. Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods. J Proteome Res. 2018 Dec 7;17(12):4023-4030. doi: 10.1021/acs.jproteome.8b00885. PubMed PMID: 30985145; PubMed Central PMCID: PMC6288998.

5. Fu L, Haage A, Kong N, Tanentzapf G, Li H. Dynamic protein hydrogels with reversibly tunable stiffness regulate human lung fibroblast spreading reversibly. Chem Commun (Camb). 2019 Apr 15. doi: 10.1039/c9cc01276a. [Epub ahead of print] PubMed PMID: 30984936.

April 15, Pubcrawler Hits:

1. Khadilkar RJ, Tanentzapf G. Septate junction components control Drosophila hematopoiesis through the Hippo pathway. Development. 2019 Apr 4;146(7). pii: dev166819. doi: 10.1242/dev.166819. PubMed PMID: 30890573.

April 8, Pubcrawler Hits:

1. Westhoff M, Eldstrom J, Murray CI, Thompson E, Fedida D. I (Ks) ion-channel pore conductance can result from individual voltage sensor movements. Proc Natl Acad Sci U S A. 2019 Mar 27. pii: 201811623. doi: 10.1073/pnas.1811623116. [Epub ahead of print] PubMed PMID: 30918124.

2. Au Yeung WK, Brind'Amour J, Hatano Y, Yamagata K, Feil R, Lorincz MC, Tachibana M, Shinkai Y, Sasaki H. Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection. Cell Rep. 2019 Apr 2;27(1):282-293.e4. doi: 10.1016/j.celrep.2019.03.002. PubMed PMID: 30943408.

3. Conroy BS, Grigg JC, Kolesnikov M, Morales LD, Murphy MEP. Staphylococcus aureus heme and siderophore-iron acquisition pathways. Biometals. 2019 Mar 25. doi: 10.1007/s10534-019-00188-2. [Epub ahead of print] PubMed PMID: 30911924.

4. Conroy BS, Grigg JC, Kolesnikov M, Morales LD, Murphy MEP. Staphylococcus aureus heme and siderophore-iron acquisition pathways. Biometals. 2019 Mar 25. doi: 10.1007/s10534-019-00188-2. [Epub ahead of print] PubMed PMID: 30911924.

5. Basson R, O'Loughlin JI, Weinberg J, Young AH, Bodnar T, Brotto LA. Dehydroepiandrosterone and cortisol as markers of HPA axis dysregulation in women with low sexual desire. Psychoneuroendocrinology. 2019 Mar 8;104:259-268. doi: 10.1016/j.psyneuen.2019.03.001. [Epub ahead of print] PubMed PMID: 30909007.

6. Buck J, Grossen P, Cullis PR, Huwyler J, Witzigmann D. Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery. ACS Nano. 2019 Apr 2. doi: 10.1021/acsnano.8b07858. [Epub ahead of print] PubMed PMID: 30908008.


March. 25, Pubcrawler Hits:

1. Ding H, Saer RG, Beatty JT. Porphyrin Excretion Resulting From Mutation of a Gene Encoding a Class I Fructose 1,6-Bisphosphate Aldolase in Rhodobacter capsulatus. Front Microbiol. 2019 Feb 22;10:301. doi: 10.3389/fmicb.2019.00301. eCollection 2019. PubMed PMID: 30853951; PubMed Central PMCID: PMC6395792.

2. Liou AY, Molday LL, Wang J, Andersen JP, Molday RS. Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. J Biol Chem. 2019 Mar 8. pii: jbc.RA118.007270. doi: 10.1074/jbc.RA118.007270. [Epub ahead of print] PubMed PMID: 30850395.

3. Freitas-Andrade M, Wang N, Bechberger JF, De Bock M, Lampe PD, Leybaert L, Naus CC. Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke. J Exp Med. 2019 Mar 14. pii: jem.20171452. doi: 10.1084/jem.20171452. [Epub ahead of print] PubMed PMID: 30872361.

4. Le Vasseur M, Chen VC, Huang K, Vogl WA, Naus CC. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers (Basel). 2019 Mar 11;11(3). pii: E343. doi: 10.3390/cancers11030343. PubMed PMID: 30862038.

5. Shafaattalab S, Li AY, Lin E, Stevens CM, Dewar LJ, Lynn FC, Sanatani S, Laksman Z, Morin RD, van Petegem F, Hove-Madsen L, Tieleman DP, Davis JP, Tibbits GF. In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants. Proc Natl Acad Sci U S A. 2019 Mar 18. pii: 201819023. doi: 10.1073/pnas.1819023116. [Epub ahead of print] PubMed PMID: 30886088.

6. Bowerman B, Sugioka K. Breaking Symmetry: Worm Cue Finally Found. Dev Cell. 2019 Mar 11;48(5):593-594. doi: 10.1016/j.devcel.2019.02.018. PubMed PMID: 30861371.

March. 11, Pubcrawler Hits:

1. Glavas MM, Hui Q, Tudurí E, Erener S, Kasteel NL, Johnson JD, Kieffer TJ. Early overnutrition reduces Pdx1 expression and induces β cell failure in Swiss Webster mice. Sci Rep. 2019 Mar 6; 9(1):3619. doi: 10.1038/s41598-019-39177-3. PubMed PMID: 30842440.

2. Latres E, Finan DA, Greenstein JL, Kowalski A, Kieffer TJ. Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy. Cell Metab. 2019 Mar 5; 29(3):545-563. doi: 10.1016/j.cmet.2019.02.007. Review. PubMed PMID: 30840911.

3. Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. Sci Rep. 2019 Mar 5; 9(1):3594. doi: 10.1038/s41598-019-40136-1. PubMed PMID: 30837605; PubMed Central PMCID: PMC6401103.

4. Pereira S, O'Dwyer SM, Webber TD, Baker RK, So V, Ellis CE, Yoon JS, Mojibian M, Glavas MM, Karunakaran S, Clee SM, Covey SD, Kieffer TJ. Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues. Sci Rep. 2019 Mar 1; 9(1):3307. doi: 10.1038/s41598-019-39498-3. PubMed PMID: 30824713; PubMed Central PMCID: PMC6397253.

5. Holman PJ, Baglot SL, Morgan E, Weinberg J. Effects of prenatal alcohol exposure on social competence: Asymmetry in play partner preference among heterogeneous triads of male and female rats. Dev Psychobiol. 2019 Mar 6. doi: 10.1002/dev.21842. [Epub ahead of print] PubMed PMID: 30843198.

7. Eid RS, Chaiton JA, Lieblich SE, Bodnar TS, Weinberg J, Galea LAM. Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu. Neurobiol Aging. 2019 Feb 2; 78:1-17. doi: 10.1016/j.neurobiolaging.2019.01.021. [Epub ahead of print] PubMed PMID: 30825663.

8. Borrel G, Adam PS, McKay LJ, Chen LX, Sierra-García IN, Sieber CMK, Letourneur Q, Ghozlane A, Andersen GL, Li WJ, Hallam SJ, Muyzer G, de Oliveira VM, Inskeep WP, Banfield JF, Gribaldo S. Wide diversity of methane and short-chain alkane metabolisms in uncultured archaea. Nat Microbiol. 2019 Mar 4. doi: 10.1038/s41564-019-0363-3. [Epub ahead of print] PubMed PMID: 30833729.

Feb. 25, Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Baldry SEL, Yang C, Tosefsky K, Balaton BP, Simpson EM, Brown CJ. How do genes that escape from X-chromosome inactivation contribute to Turner syndrome? Am J Med Genet C Semin Med Genet. 2019 Feb 19. doi: 10.1002/ajmg.c.31672. [Epub ahead of print] PubMed PMID: 30779428.

2. Cait J, Hughes MR, Zeglinski MR, Chan AW, Osterhof S, Scott RW, Canals Hernaez D, Cait A, Vogl AW, Bernatchez P, Underhill TM, Granville DJ, Murphy TH, Roskelley CD, McNagny KM. Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation. Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 201814766. doi: 10.1073/pnas.1814766116. [Epub ahead of print] PubMed PMID: 30787191.

Feb. 18, Pubcrawler Hits:

1. Haw J, Polzer J, Devine DV. Contextual factors influencing donor recruitment and cord blood collection: perspectives of frontline staff of the Canadian Blood Services' Cord Blood Bank. Transfusion. 2019 Feb 11. doi: 10.1111/trf.15185. [Epub ahead of print] PubMed PMID: 30741433.

2. Navas LE, Martínez FD, Taverna ME, Fetherolf MM, Eltis LD, Nicolau V, Estenoz D, Campos E, Benintende GB, Berretta MF. A thermostable laccase from Thermus sp. 2.9 and its potential for delignification of Eucalyptus biomass. AMB Express. 2019 Feb 12;9(1):24. doi: 10.1186/s13568-019-0748-y. PubMed PMID: 30756202.

3. Mikkelsen SA, Mogensen LS, Vilsen B, Molday RS, Vestergaard AL, Andersen JP. Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. J Biol Chem. 2019 Feb 13. pii: jbc.RA118.007240. doi: 10.1074/jbc.RA118.007240. [Epub ahead of print] PubMed PMID: 30760526.

4. Soni A, Lin C, Murphy M, Tanner ME. Peptides Containing meso-Oxa-Diaminopimelic Acid as Substrates for the Cell Shape-Determining Proteases Csd6 and Pgp2. Chembiochem. 2019 Feb 11. doi: 10.1002/cbic.201900011. [Epub ahead of print] PubMed PMID: 30746833.

5. Khater IM, Meng F, Nabi IR, Hamarneh G. Identification of Caveolin-1 Domain Signatures via Graphlet Analysis of Single Molecule Super-Resolution Data. Bioinformatics. 2019 Feb 13. doi: 10.1093/bioinformatics/btz113. [Epub ahead of print] PubMed PMID: 30759191.

6. Majewski DD, Worrall LJ, Hong C, Atkinson CE, Vuckovic M, Watanabe N, Yu Z, Strynadka NCJ. Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry. Nat Commun. 2019 Feb 7;10(1):626. doi: 10.1038/s41467-019-08477-7. PubMed PMID: 30733444; PubMed Central PMCID: PMC6367419.

7. Xu M, Singla J, Tocheva EI, Chang YW, Stevens RC, Jensen GJ, Alber F. De Novo Structural Pattern Mining in Cellular Electron Cryotomograms. Structure. 2019 Jan 31. pii: S0969-2126(19)30005-X. doi: 10.1016/j.str.2019.01.005. [Epub ahead of print] PubMed PMID: 30744995.

Feb. 11, Pubcrawler Hits:

1. Yang X, Kang N, Toyofuku WM, Scott MD. Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics. Immunobiology. 2018 Dec 28. pii: S0171-2985(18)30124-4. doi: 1016/j.imbio.2018.12.003. [Epub ahead of print] PubMed PMID: 30711357.

2. Maya-Martinez R, Alexander JAN, Otten CF, Ayala I, Vollmer D, Gray J, Bougault CM, Burt A, Laguri C, Fonvielle M, Arthur M, Strynadka NCJ, Vollmer W, Simorre JP. Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus. Front Microbiol. 2019 Jan 18;9:3223. doi: 10.3389/fmicb.2018.03223. eCollection 2018. PubMed PMID: 30713527; PubMed Central PMCID: PMC6346638.

Feb. 04, Pubcrawler Hits:

1. Tamaru Y, Yoshida M, Eltis LD, Goodell B. Multiple iron reduction by methoxylated phenolic lignin structures and the generation of reactive oxygen species by lignocellulose surfaces. Int J Biol Macromol. 2019 Jan 27;128:340-346. doi: 10.1016/j.ijbiomac.2019.01.149. [Epub ahead of print] PubMed PMID: 30699335.

2. Quancard J, Klein T, Fung SY, Renatus M, Hughes N, Israël L, Priatel JJ, Kang S, Blank MA, Viner RI, Blank J, Schlapbach A, Erbel P, Kizhakkedathu J, Villard F, Hersperger R, Turvey SE, Eder J, Bornancin F, Overall CM. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Jan 28. doi: 10.1038/s41589-018-0222-1. [Epub ahead of print] PubMed PMID: 30692685.

3. Zeytuni N, Strynadka NCJ. A Hybrid Secretion System Facilitates Bacterial Sporulation: A Structural Perspective. Microbiol Spectr. 2019 Jan;7(1). doi: 10.1128/microbiolspec.PSIB-0013-2018. PubMed PMID: 30681070.

4. Arenaz-Callao MP, González Del Río R, Lucía Quintana A, Thompson CJ, Mendoza-Losana A, Ramón-García S. Triple oral beta-lactam containing therapy for  Buruli ulcer treatment shortening. PLoS Negl Trop Dis. 2019 Jan 28; 13(1):e0007126. doi: 10.1371/journal.pntd.0007126. [Epub ahead of print] PubMed PMID: 30689630.

Jan. 21, Pubcrawler Hits:

1. Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ. Author Correction: A compendium of geochemical information from the Saanich Inlet water column. Sci Data. 2019 Jan 15; 6(1):1. doi: 10.1038/s41597-018-0005-2. PubMed PMID: 30647409; PubMed Central PMCID: PMC6333813.

2. Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, Lindenhofer D, Chen G, Boehm M, Agu CA, Yang F, Fu B, Zuber J, Knoblich JA, Kerjaschki D, Penninger JM. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019 Jan 16. doi: 10.1038/s41586-018-0858-8. [Epub ahead of print] PubMed PMID: 30651639.

Jan. 14, Pubcrawler Hits:

1. Law S, Du X, Panwar P, Honson NS, Pfeifer T, Roberge M, Brömme D.Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening. Biochem J. 2019 Jan 8. pii: BCJ20180851. doi: 10.1042/BCJ20180851. [Epub ahead of print] PubMed PMID: 30622151.

2. Spitalnik SL, Devine DV. Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains. Transfusion. 2019 Jan;59(1):2-5. doi: 10.1111/trf.15066. PubMed PMID: 30615814.

3. Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2018 Dec 21. pii: S0092-8674(18)31560-5. doi: 10.1016/j.cell.2018.11.035. [Epub ahead of print] PubMed PMID: 30612739.

4. Lo BC, Shin SB, Canals Hernaez D, Refaeli I, Yu HB, Goebeler V, Cait A, Mohn WW, Vallance BA, McNagny KM. IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella Infection. J Immunol. 2019 Jan 7. pii: ji1801308. doi: 10.4049/jimmunol.1801308. [Epub ahead of print] PubMed PMID: 30617224.

5. Yang H, Li Y, Zhao M, Wu F, Wang X, Xiao W, Wang Y, Zhang J, Wang F, Xu F, Zeng WF, Overall CM, He SM, Chi H, Xu P. Precision de novo peptide sequencing using mirror proteases of Ac-LysargiNase and trypsin for large-scale proteomics. Mol Cell Proteomics. 2019 Jan 8. pii: mcp.TIR118.000918. doi: 10.1074/mcp.TIR118.000918. [Epub ahead of print] PubMed PMID: 30622160.

6. Ng MY, Zhang H, Weil A, Singh V, Jamiolkowski R, Baradaran-Heravi A, Roberge M, Jacobson A, Friesen W, Welch E, Goldman YE, Cooperman BS. New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. ACS Med Chem Lett. 2018 Nov 21;9(12):1285-1291. doi: 10.1021/acsmedchemlett.8b00472. eCollection 2018 Dec 13. PubMed PMID: 30613341; PubMed Central PMCID: PMC6295867.

Jan. 07, Pubcrawler Hits:

1. Sturm A, Fowle DA, Jones C, Leslie K, Nomosatryo S, Henny C, Canfield DE, Crowe SA. Rates and pathways of CH(4) oxidation in ferruginous Lake Matano, Indonesia. Geobiology. 2018 Dec 28. doi: 10.1111/gbi.12325. [Epub ahead of print] PubMed PMID: 30593722.

2. Young J, Duong F. Investigating the stability of the SecA-SecYEG complex during protein translocation across the bacterial membrane. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006447. doi: 10.1074/jbc.RA118.006447. [Epub ahead of print] PubMed PMID: 30602566.

3. Perez-Borrajero C, Lin CS, Okon M, Scheu K, Graves BJ, Murphy MEP, McIntosh LP. The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J Mol Biol. 2018 Dec 28. pii: S0022-2836(18)31286-5. doi: 10.1016/j.jmb.2018.12.011. [Epub ahead of print] PubMed PMID: 30597162.

4. Zimmermann P, Messina N, Mohn WW, Finlay BB, Curtis N. Association between the intestinal microbiota and allergic sensitization, eczema, and asthma: A systematic review. J Allergy Clin Immunol. 2018 Dec 29. pii: S0091-6749(18)31431-3. doi: 10.1016/j.jaci.2018.09.025. [Epub ahead of print] PubMed PMID: 30600099.

5. Richman JM. Shedding new light on the mysteries of tooth eruption. Proc Natl Acad Sci U S A. 2019 Jan 2. pii: 201819412. doi: 10.1073/pnas.1819412116. [Epub ahead of print] PubMed PMID: 30602459.



Dec. 31, Pubcrawler Hits:

1. Kajiwara Y, Wang E, Wang M, Sin WC, Brennand KJ, Schadt E, Naus CC, Buxbaum J, Zhang B. GJA1 (connexin43) is a key regulator of Alzheimer's disease pathogenesis. Acta Neuropathol Commun. 2018 Dec 21;6(1):144. doi: 10.1186/s40478-018-0642-x. PubMed PMID: 30577786.

2. Johnson SB, Emmons EB, Lingg RT, Anderson RM, Romig-Martin SA, LaLumiere RT, Narayanan NS, Viau V, Radley JJ. Prefrontal-bed nucleus circuit modulation of a passive coping response set. J Neurosci. 2018 Dec 20. pii: 1421-18. doi: 10.1523/JNEUROSCI.1421-18.2018. [Epub ahead of print] PubMed PMID: 30573644.

Dec. 24, Pubcrawler Hits:

1. Johnson P, Arif AA, Lee-Sayer SSM, Dong Y. Hyaluronan and Its Interactions With Immune Cells in the Healthy and Inflamed Lung. Front Immunol. 2018 Nov 29; 9:2787. doi: 10.3389/fimmu.2018.02787. eCollection 2018. Review. PubMed PMID: 30555472; PubMed Central PMCID: PMC6281886.

2. Modi H, Johnson JD. Folding mutations suppress early beta-cell proliferation. Elife. 2018 Dec 14; 7. pii: e43475. doi: 10.7554/eLife.43475. PubMed PMID: 30547883; PubMed Central PMCID: PMC6294546.

3. Liu KYP, Lu XJD, Zhu YS, Le N, Kim H, Poh CF. Plasma-Derived Inflammatory Proteins Predict Oral Squamous Cell Carcinoma. Front Oncol. 2018 Dec 4; 8:585. doi: 10.3389/fonc.2018.00585. eCollection 2018. PubMed PMID: 30564558; PubMed Central PMCID: PMC6288174.

4. Chohan H, Esfandiarei M, Arman D, Van Raamsdonk CD, van Breemen C, Friedman JM, Jett KA. Neurofibromin haploinsufficiency results in altered spermatogenesis in a mouse model of neurofibromatosis type 1. PLoS One. 2018 Dec 20; 13(12):e0208835. doi: 10.1371/journal.pone.0208835. eCollection 2018. PubMed PMID: 30571760.

5. Lussier AA, Bodnar TS, Mingay M, Morin AM, Hirst M, Kobor MS, Weinberg J. Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues. Front Genet. 2018 Dec 4;9:610. doi: 10.3389/fgene.2018.00610. eCollection 2018. PubMed PMID: 30568673; PubMed Central PMCID: PMC6290329.

Dec. 17, Pubcrawler Hits:

1. Ng KW, Marshall EA, Enfield KS, Martin SD, Milne K, Pewarchuk ME, Abraham N, Lam WL. Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma. Oncoimmunology. 2018 Sep 6;7(12):e1504728. doi: 10.1080/2162402X.2018.1504728. eCollection 2018. PubMed PMID: 30524903; PubMed Central PMCID: PMC6279324.

2. Levy-Booth DJ, Giesbrecht IJW, Kellogg CTE, Heger TJ, D'Amore DV, Keeling PJ, Hallam SJ, Mohn WW. Seasonal and ecohydrological regulation of active microbial populations involved in DOC, CO(2), and CH(4) fluxes in temperate rainforest soil. ISME J. 2018 Dec 11. doi: 10.1038/s41396-018-0334-3. [Epub ahead of print] PubMed PMID: 30538276.

3. Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM. The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2018 Nov 29. pii: S0085-2538(18)30644-6. doi: 10.1016/j.kint.2018.08.037. [Epub ahead of print] PubMed PMID: 30522767.

4. Brockerman JA, Okon M, Withers SG, McIntosh LP. The pK(a) values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme. Protein Sci. 2018 Dec 7. doi: 10.1002/pro.3562. [Epub ahead of print] PubMed PMID: 30537432.

5. Ipsiroglu OS, Wind K, Hung YA, Berger M, Chan F, Yu W, Stockler S, Weinberg J. Prenatal alcohol exposure and sleep-wake behaviors: exploratory and naturalistic observations in the clinical setting and in an animal model. Sleep Med. 2018 Oct 25;54:101-112. doi: 10.1016/j.sleep.2018.10.006. [Epub ahead of print] PubMed PMID: 30530254.

Dec. 10, Pubcrawler Hits:

1. Pawluski JL, Brain U, Hammond GL, Oberlander TF. Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression. Arch Womens Ment Health. 2018 Dec 1. doi: 10.1007/s00737-018-0931-1. [Epub ahead of print] PubMed PMID: 30506371.

Dec. 03, Pubcrawler Hits:

1. Vuilleumier R, Lian T, Flibotte S, Khan ZN, Fuchs A, Pyrowolakis G, Allan DW. Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element. Nucleic Acids Res. 2018 Nov 22. doi: 10.1093/nar/gky1135. [Epub ahead of print] PubMed PMID: 30476189.

2. Kerr CH, Dalwadi U, Scott NE, Yip CK, Foster LJ, Jan E. Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells. Sci Rep. 2018 Nov 26;8(1):17353. doi: 10.1038/s41598-018-35717-5. PubMed PMID: 30478341.

3. Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G. Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo. Cell Rep. 2018 Nov 27;25(9):2401-2416.e5. doi: 10.1016/j.celrep.2018.10.098. PubMed PMID: 30485809.

Nov. 26, Pubcrawler Hits:

1. González A, Fernandino JI, Elisio M, Chalde T, Miranda LA, Hammond GL, Somoza GM. Sex Hormone Binding Globuling during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis). Gen Comp Endocrinol. 2018 Nov 19. pii: S0016-6480(18)30365-4. doi: 10.1016/j.ygcen.2018.11.010. [Epub ahead of print] PubMed PMID: 30465767.

2. Tunster SJ, Van de Pette M, Creeth HDJ, Lefebvre L, John RM. Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome. Dis Model
Mech. 2018 Nov 16;11(11). pii: dmm035832. doi: 10.1242/dmm.035832. PubMed PMID: 30158284; PubMed Central PMCID: PMC6262809.

3. Hill LA, Vassiliadi DA, Dimopoulou I, Anderson AJ, Boyle LD, Kilgour AHM, Stimson RH, Machado Y, Overall CM, Walker BR, Lewis JG, Hammond GL. Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma. J Endocrinol. 2019 Jan 1; 240(1):27-39. doi: 10.1530/JOE-18-0479. PubMed PMID: 30452386.

4. Kan B, Michalski C, Fu H, Au HHT, Lee K, Marchant EA, Cheng MF, Anderson-Baucum E, Aharoni-Simon M, Tilley P, Mirmira RG, Ross CJ, Luciani DS, Jan E, Lavoie PM. Cellular metabolism constrains innate immune responses in early human ontogeny. Nat Commun. 2018 Nov 16; 9(1):4822. doi: 10.1038/s41467-018-07215-9. PubMed PMID: 30446641; PubMed Central PMCID: PMC6240060.

5. Shimazu-Kuwahara S, Kanemaru Y, Harada N, Ikeguchi E, Ueda Y, Yamane S, Murata Y, Yasoda A, Kieffer TJ, Inagaki N. Glucose-dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance but deteriorated bone loss in ovariectomized mice. J Diabetes Investig. 2018 Nov 19. doi:10.1111/jdi.12978. [Epub ahead of print] PubMed PMID: 30451382.

6.Werth AJ, Lillie MA, Piscitelli MA, Vogl AW, Shadwick RE. Slick, stretchy fascia underlies the sliding tongue of rorquals. Anat Rec (Hoboken). 2018 Nov 17.doi: 10.1002/ar.24035. [Epub ahead of print] PubMed PMID: 30447133.

7. Fujiwara S, Hoshizaki M, Ichida Y, Lex D, Kuroda E, Ishii KJ, Magi S, Okada M, Takao H, Gandou M, Imai H, Hara R, Herzog H, Yoshimura A, Okamura H, Penninger JM, Slutsky AS, Uhlig S, Kuba K, Imai Y. Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection. Nat Microbiol. 2018 Nov 19. doi: 10.1038/s41564-018-0289-1. [Epub ahead of print] PubMed PMID: 30455472.

Nov. 12, Pubcrawler Hits:

1. Kerr CH, Wang QS, Moon KM, Keatings K, Allan DW, Foster LJ, Jan E. IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection. Nucleic Acids Res. 2018 Nov 10. doi: 10.1093/nar/gky1121. [Epub ahead of print] PubMed PMID: 30418631.

2. Roston TM, Haji-Ghassemi O, LaPage MJ, Batra AS, Bar-Cohen Y, Anderson C, Lau YR, Maginot K, Gebauer RA, Etheridge SP, Potts JE, Van Petegem F, Sanatani S. Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry. PLoS One. 2018 Nov 7; 13(11):e0205925. doi: 10.1371/journal.pone.0205925. eCollection 2018. PubMed PMID: 30403697; PubMed Central PMCID: PMC6221297.

Nov. 05, Pubcrawler Hits:

1. Marshall NC, Klein T, Thejoe M, von Krosigk N, Kizhakkedathu J, Finlay BB, Overall CM. Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation. J Proteome Res. 2018 Oct 29. doi: 10.1021/acs.jproteome.8b00675. [Epub ahead of print] PubMed PMID: 30371095.

2. Mei Y, Yu K, Lo JCY, Takeuchi LE, Hadjesfandiari N, Yazdani-Ahmadabadi H, Brooks DE, Lange D, Kizhakkedathu JN. Polymer-Nanoparticle Interaction as a Design Principle in the Development of a Durable Ultrathin Universal Binary Antibiofilm Coating with Long-Term Activity. ACS Nano. 2018 Oct 29. doi: 10.1021/acsnano.8b05512. [Epub ahead of print] PubMed PMID: 30354054.

3. McDiarmid TA, Au V, Loewen AD, Liang J, Mizumoto K, Moerman DG, Rankin CH. CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance. Dis Model Mech. 2018 Oct 25. pii: dmm.036517. doi: 10.1242/dmm.036517. [Epub ahead of print] PubMed PMID: 30361258.

4. Tham DKL, Moukhles H. Towards a better understanding of AQP4's role in astrocytic process extension: An Editorial for 'Involvement of aquaporin-4 in laminin-enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and a-syntrophin in aquaporin-4 expression' on doi:10.1111/jnc.14548. J Neurochem. 2018 Oct 30. doi: 10.1111/jnc.14590. [Epub ahead of print] PubMed PMID: 30378126.

5. Redfield RJ, Soucy SM. Evolution of Bacterial Gene Transfer Agents. Front Microbiol. 2018 Oct 25; 9:2527. doi: 10.3389/fmicb.2018.02527. eCollection 2018. PubMed PMID: 30410473; PubMed Central PMCID: PMC6209664.

6. Alexander JAN, Chatterjee SS, Hamilton SM, Eltis LD, Chambers HF, Strynadka NCJ. Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. J Biol Chem. 2018 Oct 26. pii: jbc.RA118.004952. doi: 10.1074/jbc.RA118.004952. [Epub ahead of print] PubMed PMID: 30366985.

7. Lam VYY, Raineki C, Wang LY, Chiu M, Lee G, Ellis L, Yu W, Weinberg J. Role of corticosterone in anxiety- and depressive-like behavior and HPA regulation following prenatal alcohol exposure. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Oct 24; 90:1-15. doi: 10.1016/j.pnpbp.2018.10.008. [Epub ahead of print]PubMed PMID: 30367959.

Oct. 29, Pubcrawler Hits:

1. Lemieux MJ, Denault JB, Overall CM. Highlight: Frontiers in Proteolysis. Biol Chem. 2018 Oct 26. pii: /j/bchm.ahead-of-print/hsz-2018-0401/hsz-2018-0401.xml. doi: 10.1515/hsz-2018-0401. [Epub ahead of print] PubMed PMID: 30352023.

2. Wang K, Holt C, Lu J, Brohus M, Larsen KT, Overgaard MT, Wimmer R, Van Petegem F. Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc Natl Acad Sci US A. 2018 Oct 22. pii: 201808733. doi: 10.1073/pnas.1808733115. [Epub ahead of print] PubMed PMID: 30348784.

Oct. 22, Pubcrawler Hits:

1. Thompson E, Eldstrom J, Westhoff M, McAfee D, Fedida D. The I(Ks) Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry. Biophys J. 2018 Sep 27. pii: S0006-3495(18)31072-5. doi: 10.1016/j.bpj.2018.09.018. [Epub ahead of print] PubMed PMID: 30314657.

2. Molday LL, Cheng CL, Molday RS. Cell-Specific Markers for the Identification of Retinal Cells and Subcellular Organelles by Immunofluorescence Microscopy. Methods Mol Biol. 2019;1834:293-310. doi: 10.1007/978-1-4939-8669-9_19. PubMed PMID: 30324451.

3. Adams A, Sriram A, Vogl AW. Internalization of intact intercellular junctions in the testis by clathrin/actin-mediated endocytic structures: Tubulobulbar complexes. Anat Rec (Hoboken). 2018 Oct 12. doi: 10.1002/ar.23963. [Epub ahead of print] PubMed PMID: 30312540.

4. Moukarzel S, Dyer RA, Garcia C, Wiedeman AM, Boyce G, Weinberg J, Keller BO, Elango R, Innis SM. Milk Fat Globule Membrane Supplementation in Formula-fed Rat Pups Improves Reflex Development and May Alter Brain Lipid Composition. Sci Rep. 2018 Oct 15;8(1):15277. doi: 10.1038/s41598-018-33603-8. PubMed PMID: 30323309.

Oct. 15, Pubcrawler Hits:

1. Jaeger AH, Stanley M, Weiss ZF, Musso PY, Chan RC, Zhang H, Feldman-Kiss D, Gordon MD. A complex peripheral code for salt taste in Drosophila. Elife. 2018 Oct 11;7. pii: e37167. doi: 10.7554/eLife.37167. PubMed PMID: 30307393.

2. Nayak A, Kim DY, Trnka MJ, Kerr CH, Lidsky PV, Stanley DJ, Rivera BM, Li KH, Burlingame AL, Jan E, Frydman J, Gross JD, Andino R. A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability. Cell Host Microbe. 2018 Oct 10;24(4):542-557.e9. doi: 10.1016/j.chom.2018.09.006. PubMed PMID: 30308158.

3. Myette-Côté É, Durrer C, Neudorf H, Bammert TD, Botezelli JD, Johnson JD, DeSouza CA, Little JP. Short-term low-carbohydrate high-fat diet with or without post-meal walks on glycemic control and inflammation in type 2 diabetes: A randomized trial. Am J Physiol Regul Integr Comp Physiol. 2018 Oct 10. doi: 10.1152/ajpregu.00240.2018. [Epub ahead of print] PubMed PMID: 30303707.

4. Neumann UH, Kwon MM, Baker RK, Kieffer TJ. Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice. Am J Physiol Endocrinol Metab. 2018 Oct 9. doi: 10.1152/ajpendo.00159.2018. [Epub ahead of print] PubMed PMID: 30300012.

Oct. 08, Pubcrawler Hits:

1. Mallia-Milanes B, Dufour A, Philp C, Solis N, Klein T, Fischer M, Bolton CE, Shapiro SD, Overall CM, Johnson SR. TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 4. doi: 10.1152/ajplung.00175.2018. [Epub ahead of print] PubMed PMID: 30284925.

2. Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H. Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate. Commun Biol. 2018 Aug 17;1:120. doi: 10.1038/s42003-018-0121-8. eCollection 2018. PubMed PMID: 30272000.

3. Adam N, Trumm M, Smith VC, MacGillivray RTA, Panak PJ. Incorporation of transuranium elements: coordination of Cm(iii) to human serum transferrin. Dalton Trans. 2018 Oct 1. doi: 10.1039/c8dt02915f. [Epub ahead of print]. PubMed PMID: 30270390.

Oct. 01, Pubcrawler Hits:

1. Wilhelm RC, Singh R, Eltis LD, Mohn WW. Bacterial contributions to delignification and lignocellulose degradation in forest soils with metagenomic and quantitative stable isotope probing. ISME J. 2018 Sep 26. doi: 10.1038/s41396-018-0279-6. [Epub ahead of print] PubMed PMID: 30258172.

Sep. 24, Pubcrawler Hits:

1. Boraschi-Diaz I, Mort JS, Brömme D, Senis YA, Mazharian A, Komarova SV. Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation. Bone. 2018 Sep 12;117:23-30. doi: 10.1016/j.bone.2018.09.006. [Epub ahead of print] PubMed PMID:30217615.

2. Kenward PA, Simister RL, Morgan-Lang C, Finke N, Sturm A, Hallam SJ, Crowe SA. Recovering cellular biomass from fluids using chemical flocculation. Environ Microbiol Rep. 2018 Sep 19. doi: 10.1111/1758-2229.12690. [Epub ahead of print]PubMed PMID: 30230256.

3. Leach Bennett J, Devine DV. Risk-based decision making in transfusion medicine. Vox Sang. 2018 Sep 19. doi: 10.1111/vox.12708. [Epub ahead of print] Review. PubMed PMID: 30232803.

4. Martin BJE, Chruscicki AT, Howe LJ. Transcription Promotes the Interaction of the FAcilitates Chromatin Transactions (FACT) Complex with Nucleosomes in Saccharomyces cerevisiae. Genetics. 2018 Sep 20. pii: genetics.301349.2018. doi:  10.1534/genetics.118.301349. [Epub ahead of print] PubMed PMID: 30237209.

Sep. 17, Pubcrawler Hits:

1. Pirapaharan DC, Søe K, Panwar P, Madsen JS, Bergmann ML, Overgaard M, Brömme D, Delaisse JM. A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture. Calcif Tissue Int. 2018 Sep 7. doi: 10.1007/s00223-018-0472-7. [Epub ahead of print] PubMed PMID: 30194476.

2. Pancaroglu R, Van Petegem F. Calcium Channelopathies: Structural Insights into Disorders of the Muscle Excitation-Contraction Complex. Annu Rev Genet. 2018 Sep 12. doi: 10.1146/annurev-genet-120417-031311. [Epub ahead of print] PubMed PMID: 30208288.

Sep. 10, Pubcrawler Hits:

1. von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA. Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial. Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28. PubMed PMID: 30177038.

2. Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E. Screening of red blood cells for extracellular vesicle content as a product quality indicator. Transfusion. 2018 Aug 31. doi: 10.1111/trf.14782. [Epub ahead of print] PubMed PMID: 30168148.

Sep. 3, Pubcrawler Hits:

1. Dalal K, Ban F, Li H, Morin H, Roshan-Moniri M, Tam KJ, Shepherd A, Sharma A, Peacock J, Carlson ML, LeBlanc E, Perez C, Duong F, Ong CJ, Rennie PS, Cherkasov A. Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer. Cancer Lett. 2018 Aug 27; 437:35-43. doi: 10.1016/j.canlet.2018.08.016. [Epub ahead of print] PubMed PMID: 30165195.

Aug 27, Pubcrawler Hits:

1. Lei CL, Kellard JA, Hara M, Johnson JD, Rodriguez B, Briant LJB. Beta-cell hubs maintain Ca(2+) oscillations in human and mouse islet simulations. Islets. 2018;10(4):151-167. doi: 10.1080/19382014.2018.1493316. PubMed PMID: 30142036.

2. Kalathottukaren MT, Creagh AL, Abbina S, Lu G, Karbarz MJ, Pandey A, Conley PB, Kizhakkedathu JN, Haynes C. Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors. Blood Adv. 2018 Aug 28;2(16):2104-2114. doi: 10.1182/bloodadvances.2016003616. PubMed PMID: 30135185.

3. Meneksedag-Erol D, Kizhakkedathu JN, Tang T, Uludağ H. Molecular Dynamics Simulations on Nucleic Acid Binding Polymers Designed To Arrest Thrombosis. ACS Appl Mater Interfaces. 2018 Aug 20. doi: 10.1021/acsami.8b09914. [Epub ahead of print] PubMed PMID: 30085650.

4. Brind'Amour J, Kobayashi H, Richard Albert J, Shirane K, Sakashita A, Kamio A, Bogutz A, Koike T, Karimi MM, Lefebvre L, Kono T, Lorincz MC. LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation. Nat Commun. 2018 Aug 20;9(1):3331. doi: 10.1038/s41467-018-05841-x. PubMed PMID: 30127397; PubMed Central PMCID: PMC6102241.

5. Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Snyder M, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project. J Proteome Res. 2018 Aug 23. doi: 10.1021/acs.jproteome.8b00441. [Epub ahead of print] PubMed PMID: 30099871.

6. Blaukopf M, Worrall L, Kosma P, Strynadka NCJ, Withers SG. Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex. Structure. 2018 Jul 23. pii: S0969-2126(18)30247-8. doi: 10.1016/j.str.2018.07.001. [Epub ahead of print] PubMed PMID: 30122450.

Aug 20, Pubcrawler Hits:

1. Carlson ML, Young JW, Zhao Z, Fabre L, Jun D, Li J, Li J, Dhupar HS, Wason I, Mills AT, Beatty JT, Klassen JS, Rouiller I, Duong F. The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution. Elife. 2018  Aug 15;7. pii: e34085. doi: 10.7554/eLife.34085. PubMed PMID: 30109849; PubMed Central PMCID: PMC6093710.

2. Bogutz AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, Gu T, Gertsenstein M, Nagy A, Lefebvre L. Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. PLoS Genet. 2018 Aug 10;14(8):e1007587. doi: 10.1371/journal.pgen.1007587. [Epub ahead of print] PubMed PMID: 30096149.

3. Bergeron JRC, Brockerman JA, Vuckovic M, Deng W, Okon M, Finlay BB, McIntosh LP, Strynadka NCJ. Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. Protein Sci. 2018 Aug 10. doi: 10.1002/pro.3447.[Epub ahead of print] PubMed PMID: 30095200.

4. Holman PJ, Ellis L, Morgan E, Weinberg J. Prenatal alcohol exposure disrupts male adolescent social behavior and oxytocin receptor binding in rodents. Horm Behav. 2018 Aug 16;105:115-127. doi: 10.1016/j.yhbeh.2018.08.004. [Epub ahead of print] PubMed PMID: 30110605.

5. Nassar R, Wong E, Bui JM, Yip CK, Li H, Gsponer J, Lamour G. Mechanical Anisotropy in GNNQQNY Amyloid Crystals. J Phys Chem Lett. 2018 Aug 15:4901-4909. doi: 10.1021/acs.jpclett.8b02027. [Epub ahead of print] PubMed PMID: 30102541.

Aug 13, Pubcrawler Hits:

1. Zatmári D, Xue B, Kannan B, Burtnick LD, Bugyi B, Nyitrai M, Robinson RC. ATP competes with PIP2 for binding to gelsolin. PLoS One. 2018 Aug 7;13(8):e0201826. doi: 10.1371/journal.pone.0201826. eCollection 2018. PubMed PMID: 30086165.

2. Liu MM, Boinett CJ, Chan ACK, Parkhill J, Murphy MEP, Gaynor EC. Investigating the Campylobacter jejuni Transcriptional Response to Host Intestinal Extracts Reveals the Involvement of a Widely Conserved Iron Uptake System. MBio. 2018 Aug 7; 9(4). pii: e01347-18. doi: 10.1128/mBio.01347-18. PubMed PMID: 30087169.

3. Wang C, Fung G, Deng H, Jagdeo J, Mohamud Y, Xue YC, Jan E, Hirota JA, Luo H. NLRP3 deficiency exacerbates enterovirus infection in mice. FASEB J. 2018 Aug 6:fj201800301RRR. doi: 10.1096/fj.201800301RRR. [Epub ahead of print] PubMed PMID: 30080445.

4. Fukuda Y, Matsusaki T, Tse KM, Mizohata E, Murphy MEP, Inoue T. Crystallographic study of dioxygen chemistry in a copper-containing nitrite reductase from Geobacillus thermodenitrificans. Acta Crystallogr D Struct Biol. 2018 Aug 1;74(Pt 8):769-777. doi: 10.1107/S2059798318010082. Epub 2018 Jul 24. PubMed PMID: 30082512.

Aug 06, Pubcrawler Hits:

1. Chen X, Shibata AC, Hendi A, Kurashina M, Fortes E, Weilinger NL, MacVicar BA, Murakoshi H, Mizumoto K. Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans. Elife. 2018 Jul 31;7. pii: e38801. doi: 10.7554/eLife.38801. PubMed PMID: 30063210.

2. Pryzdial ELG, Lee FMH, Lin BH, Carter RLR, Tegegn TZ, Belletrutti MJ. Blood coagulation dissected. Transfus Apher Sci. 2018 Jul 20. pii: S1473-0502(18)30281-7. doi: 10.1016/j.transci.2018.07.003. [Epub ahead of print] Review. PubMed PMID: 30049564.

3. Neuenschwander R, Hookenson K, Brain U, Grunau RE, Devlin AM, Weinberg J, Diamond A, Oberlander TF. Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls. Dev Psychopathol. 2018 Aug;30(3):953-969. doi: 10.1017/S095457941800041X. PubMed PMID: 30068413.

Jul 30, Pubcrawler Hits:

1. Chen S, Zaifman J, Kulkarni JA, Zhigaltsev IV, Tam YK, Ciufolini MA, Tam YYC, Cullis PR. Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids. J Control Release.2018 Jul 17;286:46-54. doi: 10.1016/j.jconrel.2018.07.026. [Epub ahead of print] PubMed PMID: 30026080.

2. Thompson E, Eldstrom J, Fedida D. Single channel kinetic analysis of the cAMP effect on I(Ks) mutants, S209F and S27D/S92D. Channels (Austin). 2018 Jul 20.doi: 10.1080/19336950.2018.1499369. [Epub ahead of print] PubMed PMID: 30027808.

3. Volkers G, Lizak C, Niesser J, Rosell FI, Preidl J, Gnanapragassam VS, Horstkorte R, Rademann J, Strynadka NCJ. Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family. ACS Chem Biol. 2018 Jul 26. doi: 10.1021/acschembio.8b00478. [Epub ahead of print] PubMed PMID: 30015474.

4. Dornan GL, Dalwadi U, Hamelin DJ, Hoffmann RM, Yip CK, Burke JE. Probing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex. J Mol Biol. 2018 Jul 18. pii: S0022-2836(18)30564-3. doi: 10.1016/j.jmb.2018.07.020. [Epub ahead of print] PubMed PMID: 30031006.

Jul 23, Pubcrawler Hits:

1. Gao P, Ho PL, Yan B, Sze KH, Davies J, Kao RYT. Suppression of Staphylococcus aureus virulence by a small-molecule compound. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520. doi: 10.1073/pnas.1720520115. [Epub ahead of print] PubMed PMID: 30012613.

2. Blackmore S, Vriens B, Sorensen M, Power IM, Smith L, Hallam SJ, Mayer KU, Beckie RD. Microbial and geochemical controls on waste rock weathering and drainage quality. Sci Total Environ. 2018 Nov 1;640-641:1004-1014. doi: 10.1016/j.scitotenv.2018.05.374. Epub 2018 Jun 5. PubMed PMID: 30021267.

3. Armstrong Z, Mewis K, Liu F, Morgan-Lang C, Scofield M, Durno E, Chen HM, Mehr K, Withers SG, Hallam SJ. Metagenomics reveals functional synergy and novel polysaccharide utilization loci in the Castor canadensis fecal microbiome. ISMEJ. 2018 Jul 16. doi: 10.1038/s41396-018-0215-9. [Epub ahead of print] PubMed PMID: 30013164.

4. Wang J, Molday LL, Hii T, Coleman JA, Wen T, Andersen JP, Molday RS. Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. Sci Rep. 2018 Jul 17;8(1):10795. doi: 10.1038/s41598-018-29108-z. PubMed PMID: 30018401; PubMed Central PMCID: PMC6050252.

5. McMillan HJ, Telegrafi A, Singleton A, Cho MT, Lelli D, Lynn FC, Griffin J, Asamoah A, Rinne T, Erasmus CE, Koolen DA, Haaxma CA, Keren B, Doummar D, Mignot C, Thompson I, Velsher L, Dehghani M, Vahidi Mehrjardi MY, Maroofian R, Tchan M, Simons C, Christodoulou J, Martín-Hernández E, Guillen Sacoto MJ, Henderson LB, McLaughlin H, Molday LL, Molday RS, Yoon G. Recessive mutations in ATP8A2 cause severe hypotonia, cognitive impairment, hyperkinetic movement disorders and progressive optic atrophy. Orphanet J Rare Dis. 2018 May 31;13(1):86. doi: 10.1186/s13023-018-0825-3. PubMed PMID: 30012219; PubMed Central PMCID: PMC6048855.

6. Richter A, Strauch A, Chao J, Ko M, Av-Gay Y. Screening of preselected libraries targeting Mycobacterium abscessus for drug discovery. Antimicrob Agents Chemother. 2018 Jul 16. pii: AAC.00828-18. doi: 10.1128/AAC.00828-18. [Epub ahead of print] PubMed PMID: 30012760.

Jul 16, Pubcrawler Hits:

1. Ding H, Caza M, Dong Y, Arif AA, Horianopoulos LC, Hu G, Johnson P, Kronstad JW. ATG genes influence the virulence of Cryptococcus neoformans through contributions beyond core autophagy functions. Infect Immun. 2018 Jul 9. pii: IAI.00069-18. doi: 10.1128/IAI.00069-18. [Epub ahead of print] PubMed PMID: 29986893.

2. Lam VYY, Raineki C, Ellis L, Yu W, Weinberg J. Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: Sex- and time-dependent effects. Psychoneuroendocrinology. 2018 Jun 23;97:8-19. doi: 10.1016/j.psyneuen.2018.06.018. [Epub ahead of print] PubMed PMID: 29990678.

Jul 09, Pubcrawler Hits:

1. Vuillemin A, Horn F, Friese A, Winkel M, Alawi M, Wagner D, Henny C, Orsi WD, Crowe SA, Kallmeyer J. Metabolic potential of microbial communities from ferruginous sediments. Environ Microbiol. 2018 Jul 2. doi: 10.1111/1462-2920.14343. [Epub ahead of print] PubMed PMID: 29968357.

2. Fedida D. Modeling the Hidden Pathways of IKs Channel Activation. Biophys J. 2018 Jul 3;115(1):1-2. doi: 10.1016/j.bpj.2018.05.020. PubMed PMID: 29972801.

Jul 02, Pubcrawler Hits:

1. Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, Franzke CW, Overall CM, Granville DJ. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction. Sci Rep. 2018 Jun 26;8(1):9690. doi: 10.1038/s41598-018-28070-0. PubMed PMID: 29946113.

Jun 25, Pubcrawler Hits:

1. Snieckus V, Hurst T, Nerdinger S, Kautsjah E, Eltis L, Kahlenberg V, Schlapp-Hackl I. Bacterial Catabolism of Biphenyls. Synthesis and Evaluation of Analogues. Chembiochem. 2018 Jun 15. doi: 10.1002/cbic.201800231. [Epub ahead of print] PubMed PMID: 29905982.

2. Richard Albert J, Koike T, Younesy H, Thompson R, Bogutz AB, Karimi MM, Lorincz MC. Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA). BMC Genomics. 2018 Jun 15;19(1):463. doi: 10.1186/s12864-018-4835-2. PubMed PMID: 29907088.

3. van Pel DM, Harada K, Song D, Naus CC, Sin WC. Modelling glioma invasion using 3D bioprinting and scaffold-free 3D culture. J Cell Commun Signal. 2018 Jun 16. doi: 10.1007/s12079-018-0469-z. [Epub ahead of print] PubMed PMID: 29909492.

4. Dufour A, Bellac CL, Eckhard U, Solis N, Klein T, Kappelhoff R, Fortelny N, Jobin P, Rozmus J, Mark J, Pavlidis P, Dive V, Barbour SJ, Overall CM. C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease. Nat Commun. 2018 Jun 20;9(1):2416. doi: 10.1038/s41467-018-04717-4. PubMed PMID: 29925830.

Jun 18, Pubcrawler Hits:

1. Crowe SA, Cox RP, Jones C, Fowle DA, Santibañez-Bustos JF, Ulloa O, Canfield DE. Decrypting the sulfur cycle in oceanic oxygen minimum zones. ISME J. 2018 Jun 7; doi: 10.1038/s41396-018-0149-2. [Epub ahead of print] PubMed PMID: 29884830.

2. Khater IM, Meng F, Wong TH, Nabi IR, Hamarneh G. Super Resolution Network Analysis Defines the Molecular Architecture of Caveolae and Caveolin-1 Scaffolds. Sci Rep. 2018 Jun 13;8(1):9009. doi: 10.1038/s41598-018-27216-4. PubMed PMID: 29899348.

3. Caveney NA, Li FK, Strynadka NC. Enzyme structures of the bacterial peptidoglycan and wall teichoic acid biogenesis pathways. Curr Opin Struct Biol. 2018 Jun 6;53:45-58. doi: 10.1016/ [Epub ahead of print] Review. PubMed PMID: 29885610.

Jun 11, Pubcrawler Hits:

1. Loghmani H, Conway EM. Exploring traditional and non-traditional roles for thrombomodulin. Blood. 2018 Jun 4. pii: blood-2017-12-768994. doi: 10.1182/blood-2017-12-768994. [Epub ahead of print] PubMed PMID: 29866818.

2. Schubert P, Johnson L, Marks DC, Devine DV. Ultraviolet-Based Pathogen Inactivation Systems: Untangling the Molecular Targets Activated in Platelets. Front Med (Lausanne). 2018 May 7;5:129. doi: 10.3389/fmed.2018.00129. eCollection Review. PubMed PMID: 29868586; PubMed Central PMCID: PMC5949320.

3. Heinkel F, Shen L, Richard-Greenblatt M, Okon M, Bui JM, Gee CL, Gay LM, Alber T, Av-Gay Y, Gsponer J, McIntosh LP. Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747. Structure. 2018 May 17. pii: S0969-2126(18)30164-3. doi: 10.1016/j.str.2018.04.018. [Epub ahead of print] PubMed PMID: 29861345.

Jun 2, Pubcrawler Hits:

1. Garces F, Jiang K, Molday LL, Stöhr H, Weber BH, Lyons CJ, Maberley D, Molday RS. Correlating the Expression and Functional Activity of ABCA4 Disease Variants With the Phenotype of Patients With Stargardt Disease. Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2305-2315. doi: 10.1167/iovs.17-23364. PubMed PMID: 29847635; PubMed Central PMCID: PMC5937799

2. Grek CL, Sheng Z, Naus CC, Sin WC, Gourdie RG, Ghatnekar GG. Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics. Curr Opin Pharmacol. 2018 May 24;41:79-88. doi: 10.1016/j.coph.2018.05.002. [Epub ahead of print] Review. PubMed PMID: 29803991. 

May 28, Pubcrawler Hits:

1. Tharmarajah G, Eckhard U, Jain F, Marino G, Prudova A, Urtatiz O, Fuchs H, Hrabe de Angelis M, Overall CM, Van Raamsdonk CD. Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase. Pigment Cell Melanoma Res. 2018 May 21. doi: 10.1111/pcmr.12711. [Epub ahead of print] PubMed PMID: 29781574.

May 21, Pubcrawler Hits:

1. Siren EMJ, Chapanian R, Constantinescu I, Brooks DE, Kizhakkedathu JN. Oncotically Driven Control over Glycocalyx Dimension for Cell Surface Engineering and Protein Binding in the Longitudinal Direction. Sci Rep. 2018 May 15; 8(1):7581. doi: 10.1038/s41598-018-25870-2. PubMed PMID: 29765073.

2. Han B, Guan Q, Chafeeva I, Mendelson AA, Roza GD, Liggins R, Kizhakkedathu JN, Du C. Peritoneal and Systemic Responses of Obese Type II Diabetic Rats to Chronic Exposure to a Hyperbranched Polyglycerol-based Dialysis Solution. Basic Clin Pharmacol Toxicol. 2018 May 12. doi: 10.1111/bcpt.13038. [Epub ahead of print] PubMed PMID: 29753311.

3. Pryjma M, Burian J, Thompson CJ. Rifabutin acts in synergy and is bactericidal with frontline Mycobacterium abscessus antibiotics clarithromycin and tigecycline, suggesting a potent treatment combination. Antimicrob Agents Chemother. 2018 May 14. pii: AAC.00283-18. doi: 10.1128/AAC.00283-18. [Epub ahead of print] PubMed PMID: 29760147.

May 14, Pubcrawler Hits:

1. Li RC, Lin CC, Ren X, Wu JS, Molday LL, Molday RS, Yau KW. Ca(2+)-activated Cl current predominates in threshold response of mouse olfactory receptor neurons. Proc Natl Acad Sci U S A. 2018 May 7. pii: 201803443. doi: 10.1073/pnas.1803443115. [Epub ahead of print] PubMed PMID: 29735665.

2. Dhanda AS, Lulic KT, Vogl AW, Mc Gee MM, Chiu RH, Guttman JA. Listeria membrane protrusion collapse: Requirement of Cyclophilin A for Listeria cell-to-cell spreading. J Infect Dis. 2018 May 4. doi: 10.1093/infdis/jiy255. [Epub ahead of print] PubMed PMID: 29733369.

3. Bodnar TS, Raineki C, Wertelecki W, Yevtushok L, Plotka L, Zymak-Zakutnya N, Honerkamp-Smith G, Wells A, Rolland M, Woodward TS, Coles CD, Kable JA, Chambers CD, Weinberg J. Altered maternal immune networks are associated with adverse child neurodevelopment: Impact of alcohol consumption during pregnancy. Brain Behav Immun. 2018 May 5. pii: S0889-1591(18)30175-2. doi: 10.1016/j.bbi.2018.05.004. [Epub ahead of print] PubMed PMID: 29738852.

May 7, Pubcrawler Hits:

1. Daniel E, Daudé M, Kolotuev I, Charish K, Auld V, Le Borgne R. Coordination of Septate Junctions Assembly and Completion of Cytokinesis in Proliferative Epithelial Tissues. Curr Biol. 2018 Apr 20. pii: S0960-9822(18)30363-4. doi: 10.1016/j.cub.2018.03.034. Epub ahead of print] PubMed PMID: 29706514.

2. Laqua K, Klemm M, Richard-Greenblatt M, Richter A, Liebe L, Huang T, Lin S, Guardia A, Pérez-Herran E, Ballell L, Av-Gay Y, Imming P. Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides. Bioorg Med Chem. 2018 Apr 22. pii: S0968-0896(18)30460-7. doi: 10.1016/j.bmc.2018.04.045. [Epub ahead of print] PubMed PMID: 29706526. 

Apr 30 Pubcrawler Hits:

1. Balaton BP, Dixon-McDougall T, Peeters SB, Brown CJ. The eXceptional nature of the X chromosome. Hum Mol Genet. 2018 Apr 26. doi: 10.1093/hmg/ddy148. [Epub ahead of print] PubMed PMID: 29701779.

2. Kulkarni JA, Cullis PR, van der Meel R. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility. Nucleic Acid Ther. 2018 Apr 23. doi: 10.1089/nat.2018.0721. [Epub ahead of print] PubMed PMID: 29683383.

3. Wang JC, Bolger-Munro M, Gold MR. Visualizing the Actin and Microtubule Cytoskeletons at the B-cell Immune Synapse Using Stimulated Emission Depletion (STED) Microscopy. J Vis Exp. 2018 Apr 9;(134). doi: 10.3791/57028. PubMed PMID: 29683438.

4. Lee-Sayer SSM, Dougan MN, Cooper J, Sanderson L, Dosanjh M, Maxwell CA, Johnson P. CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment. PLoS One. 2018 Apr 23;13(4):e0196011. doi: 10.1371/journal.pone.0196011. eCollection 2018. PubMed PMID: 29684048.

5. Stahl M, Tremblay S, Montero M, Vogl W, Xia L, Jacobson K, Menendez A, Vallance BA. The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion. Am J Physiol Gastrointest Liver Physiol. 2018 Apr 26. doi: 10.1152/ajpgi.00264.2017. [Epub ahead of print] PubMed PMID: 29698056.

6. Lillie MA, Vogl AW, Raverty S, Haulena M, McLellan WA, Stenson GB, Shadwick RE. The caval sphincter in cetaceans and its predicted role in controlling venous flow during a dive. J Exp Biol. 2018 Apr 19. pii: jeb.177212. doi: 10.1242/jeb.177212. [Epub ahead of print] PubMed PMID: 29674378.

Apr 23 Pubcrawler Hits:

1. Louca S, Polz MF, Mazel F, Albright MBN, Huber JA, O'Connor MI, Ackermann M, Hahn AS, Srivastava DS, Crowe SA, Doebeli M, Parfrey LW. Function and functional redundancy in microbial systems. Nat Ecol Evol. 2018 Apr 16. doi:10.1038/s41559-018-0519-1. [Epub ahead of print] Review. PubMed PMID: 29662222.

2. Irwin NAT, Martin BJE, Young BP, Browne MJG, Flaus A, Loewen CJR, Keeling PJ, Howe LJ. Viral proteins as a potential driver of histone depletion in dinoflagellates. Nat Commun. 2018 Apr 18; 9(1):1535. doi: 10.1038/s41467-018-03993-4. PubMed PMID: 29670105; PubMed Central PMCID: PMC5906630.

Apr 16 Pubcrawler Hits:

1. Kulkarni JA, Darjuan MM, Mercer JE, Chen S, van der Meel R, Thewalt JL, Tam YYC, Cullis PR. On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA. ACS Nano. 2018 Apr 6. doi: 10.1021/acsnano.8b01516. [Epub ahead of print] PubMed PMID: 29614232.

2. Page MM, Johnson JD. Mild Suppression of Hyperinsulinemia to Treat Obesity and Insulin Resistance. Trends in Endocrinology & Metabolism. 2018 Apr 15. DOI:

3. Dhanda AS, Vogl AW, Albraiki SE, Otey CA, Beck MR, Guttman JA. Palladin Compensates for the Arp2/3 Complex and Supports Actin Structures during Listeria Infections. MBio. 2018 Apr 10;9(2). pii: e02259-17. doi: 10.1128/mBio.02259-17. PubMed PMID: 29636431; PubMed Central PMCID: PMC5893873.

Apr 9 Pubcrawler Hits:

1. Abramyan J, Richman JM. Craniofacial development: discoveries made in the chicken embryo. Int J Dev Biol. 2018;62(1-2-3):97-107. doi: 10.1387/ijdb.170321ja. PubMed PMID: 29616744.

Apr 2 Pubcrawler Hits:

1. Crowe AM, Workman SD, Watanabe N, Worrall LJ, Strynadka NCJ, Eltis LD. IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase. Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 201717015. doi:10.1073/pnas.1717015115. [Epub ahead of print] PubMed PMID: 29581275.

2. Adams WK, D'souza AM, Sussman JL, Kaur S, Kieffer TJ, Winstanley CA. Enhanced amphetamine-induced motor impulsivity and mild attentional impairment in theleptin-deficient rat model of obesity. Physiol Behav. 2018 Mar 27. pii:S0031-9384(18)30150-1. doi: 10.1016/j.physbeh.2018.03.027. [Epub ahead of print] PubMed PMID: 29601831.

3. Mafi A, Abbina S, Kalathottukaren MT, Morrissey JH, Haynes C, Kizhakkedathu JN, Pfaendtner J, Chou KC. Design of Polyphosphate Inhibitors: A Molecular Dynamics Investigation on Polyethylene Glycol-Linked Cationic Binding Groups. Biomacromolecules. 2018 Mar 23. doi: 10.1021/acs.biomac.8b00327. [Epub ahead of print] PubMed PMID: 29539260.

4. Wiesenfahrt T, Duanmu J, Snider F, Moerman D, Au V, Li-Leger E, Flibotte S, Parker DM, Marshall CJ, Osborne Nishimura E, Mains PE, McGhee JD. A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2. G3 (Bethesda). 2018 Mar 28. pii: g3.200079.2018. doi: 10.1534/g3.118.200079. [Epub ahead of print] PubMed PMID: 29593072.

5. Wang JSH, Freitas-Andrade M, Bechberger JF, Naus C, Yeung KK, Whitehead SN. MALDI IMS of Intraperitoneally Injected Danegaptide (ZP1609) for Treatment of Stroke-Reperfusion Injury in Mice. Rapid Commun Mass Spectrom. 2018 Mar 25. doi: 10.1002/rcm.8115. [Epub ahead of print] PubMed PMID: 29575411.

6. King SL, Goth CK, Eckhard U, Joshi HJ, Haue AD, Vakhrushev S, Schjoldager K, Overall CM, Wandall HH. TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation. J Biol Chem. 2018 Mar 28. pii: bc.RA118.001978. doi: 10.1074/jbc.RA118.001978. [Epub ahead of print]PubMed PMID: 29593093.

7. Kang N, Guo Q, Islamzada E, Ma H, Scott MD. Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation. Integr Biol (Camb). 2018 Mar 23. doi: 10.1039/C7IB00191F. [Epub ahead of print] PubMed PMID: 29570200.

8. Majewski DD, Worrall LJ, Strynadka NC. Secretins revealed: structural insights into the giant gated outer membrane portals of bacteria. Curr Opin Struct Biol. 2018 Mar 23;51:61-72. doi: 10.1016/ [Epub ahead of print] Review. PubMed PMID: 29579693.

9. Lam VYY, Raineki C, Takeuchi LE, Ellis L, Woodward TS, Weinberg J. Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects. Front Behav Neurosci. 2018 Mar 9;12:42. doi: 10.3389/fnbeh.2018.00042. eCollection 2018. PubMed PMID: 29593510; PubMed Central PMCID: PMC5855032.

Mar 19 Pubcrawler Hits:

1. Gardill BR, Rivera-Acevedo RE, Tung CC, Okon M, McIntosh LPVan Petegem F. The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations. Sci Rep. 2018 Mar 14;8(1):4483. doi: 10.1038/s41598-018-22713-y. PMID: 29540853.

2.  Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Dev Dyn. 2018 Mar 13. doi: 10.1002/dvdy.24626. [Epub ahead of print]. PMID: 29532564.

3. Tang WL, Tang WH, Szeitz A, Kulkarni J, Cullis P, Li SD. Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery. Biomaterials. 2018 Mar 3;166:13-26. doi: 10.1016/j.biomaterials.2018.03.004. [Epub ahead of print]. PMID: 29529479.

Mar 12 Pubcrawler Hits:

1. Foley JH, Conway EM. Basic weapons to degrade C3a and C5a. J Thromb Haemost. 2018 Mar 8. doi: 10.1111/jth.13999. [Epub ahead of print]. PMID: 29518284.

2. Conway EM. Complement-coagulation connections. Blood Coagul Fibrinolysis. 2018 Mar 6. doi: 10.1097/MBC.0000000000000720. [Epub ahead of print]. PMID: 29517503.

Feb 26 Pubcrawler Hits:

1. Cain SM, Tyson JR, Choi HB, Ko R, Lin PJC, LeDue JM, Powell KL, Bernier LP, Rungta RL, Yang Y, Cullis PR, O'Brien TJ, MacVicar BA, Snutch TP. CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons. Epilepsia. 2018 Feb 21. doi: 10.1111/epi.14018. [Epub ahead of print. PMID: 29468672.

2. Setiaputra D, Ahmad S, Dalwadi U, Steunou AL, Lu S, Ross JD, Dong MQ, Côté J, Yip CKMolecular architecture of the essential yeast histone acetyltransferase complex NuA4 redefines its multi-modularity. Mol Cell Biol. 2018 Feb 20. pii: MCB.00570-17. doi: 10.1128/MCB.00570-17. [Epub ahead of print] PMID: 29463645.

3. Wang JC, Lee JY, Dang-Lawson M, Pritchard C, Gold MR. The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center.  2018 Feb 19:0. doi: 10.1080/21541248.2018.1441626. [Epub ahead of print]. PMID: 29457987.

4. Cardenas E, Orellana LH, Konstantinidis KT, Mohn WW. Effects of timber harvesting on the genetic potential for carbon and nitrogen cycling in five North American forest ecozones. Sci Rep. 2018 Feb 16;8(1):3142. doi: 10.1038/s41598-018-21197-0. PMID: 29453368.

Feb 19 Pubcrawler Hits:

1. Millar D, Murphy L, Labrie A, Maurer-Spurej E. Routine Screening Method for Microparticles in Platelet Transfusions. J Vis Exp. 2018 Jan 31. doi: 10.3791/56893. PMID: 29443045.

2. Dommerholt MB, Dionne DA, Hutchinson DF, Kruit JK, Johnson JD. Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage. J Endocrinol. 2018 Feb 9. doi: 10.1530/JOE-17-0505. [Epub ahead of print] PMID: 29439088.

3. Jagdeo JM, Dufour A, Klein T, Solis N, Kleifeld O, Kizhakkedathu J, Luo H, Overall CMJan E. N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection. J Virol. 2018 Feb 7. doi: 10.1128/JVI.02211-17. [Epub ahead of print] PMID: 29437971.

4. Farr Zuend C, Nomellini JF, Smit JHorwitz MS. Generation of a Dual-Target, Safe, Inexpensive Microbicide that Protects Against HIV-1 and HSV-2 Disease.  2018 Feb 12;8(1):2786. doi: 10.1038/s41598-018-21134-1. PMID: 29434285.

5. Johnston ZC, Bellingham M, Filis P, Soffientini U, Hough D, Bhattacharya S, Simard M, Hammond GL, King P, O'Shaughnessy PJ, Fowler PA. The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester. BMC Med. 2018 Feb 12;16(1):23. doi: 10.1186/s12916-018-1009-7. PMID: 29429410.

Feb 12 Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Simpson EM, Brown CJ. Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse. Hum Mol Genet. 2018 Feb 1. doi: 10.1093/hmg/ddy039. [Epub ahead of print] PubMed PMID: 29401310.

2. Saber N, Bruin JE, O'Dwyer S, Schuster H, Rezania A, Kieffer TJ. Sex differences in maturation of human embryonic stem cell-derived beta cells in mice. Endocrinology. 2018 Feb 5. doi: 10.1210/en.2018-00048. [Epub ahead of print] PubMed PMID: 29420708.

3. De Silva E, Kim H. Drug-induced thrombocytopenia: Focus on platelet apoptosis. Chem Biol Interact. 2018 Feb 1. pii: S0009-2797(17)30840-2. doi: 10.1016/j.cbi.2018.01.015. [Epub ahead of print] Review. PubMed PMID: 29410286.

4. Hayes M, Choudhary V, Ojha N, Shin JJ, Han GS, Carman GM, Loewen CJ, Prinz WA, Levine T. Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes. Microb Cell. 2017 Dec 28;5(2):88-103. doi: 10.15698/mic2018.02.614. PubMed PMID: 29417057; PubMed Central PMCID: PMC5798408.

5. Heger TJ, Giesbrecht IJW, Gustavsen J, Del Campo J, Kellogg CTE, Hoffman KM, Lertzman K, Mohn WW, Keeling PJ. High-throughput environmental sequencing reveals high diversity of litter and moss associated protist communities along a gradient of drainage and tree productivity. Environ Microbiol. 2018 Feb 7. doi: 10.1111/1462-2920.14061. [Epub ahead of print] PubMed PMID: 29417706.

Feb 05 Pubcrawler Hits:

1. Fakhraee M, Crowe SA, Katsev S. Sedimentary sulfur isotopes and Neoarchean ocean oxygenation. Sci Adv. 2018 Jan 24;4(1):e1701835. doi: 10.1126/sciadv.1701835. eCollection 2018 Jan. PubMed PMID: 29376118; PubMed Central PMCID: PMC5783677.

2. Devine DV. Pathogen Inactivation Strategies to Improve Blood Safety: Let's Not Throw Pathogen-Reduced Platelets Out With Their Bath Water. JAMA Oncol. 2018 Feb doi: 10.1001/jamaoncol.2017.4949. [Epub ahead of print] PubMed PMID: 29392303.

3. Wang JC, Bolger-Munro M, Gold MR. Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods Mol Biol. 2018;1707:131-161. doi: 10.1007/978-1-4939-7474-0_10. PubMed PMID: 29388105.

4. Holert J, Cardenas E, Bergstrand LH, Zaikova E, Hahn AS, Hallam SJ, Mohn WW. Metagenomes Reveal Global Distribution of Bacterial Steroid Catabolism in Natural, Engineered, and Host Environments. MBio. 2018 Jan 30;9(1). pii:e02345-17. doi: 10.1128/mBio.02345-17. PubMed PMID: 29382738. 

Jan 29 Pubcrawler Hits:

1. Kumar P, Kizhakkedathu JN, Straus SK. Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo. Biomolecules. 2018 Jan 19;8(1). pii: E4. doi: 10.3390/biom8010004. Review. PubMed PMID: 29351202.

2. Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut. 2018 Jan 23. pii: gutjnl-2017-314426. doi: 10.1136/gutjnl-2017-314426. [Epub ahead of print] PubMed PMID: 29363536.

3. Kaiser JC, King AN, Grigg JC, Sheldon JR, Edgell DR, Murphy MEP, Brinsmade SR, Heinrichs DE. Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide. PLoS Genet. 2018 Jan 22;14(1):e1007159. doi: 10.1371/journal.pgen.1007159. [Epub ahead of print] PubMed PMID: 29357354.

4. Campiglio M, Costé de Bagneaux P, Ortner NJ, Tuluc P, Van Petegem F, Flucher BE. STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation. Proc Natl Acad Sci U S A. 2018 Jan 23. pii: 201715997. doi: 10.1073/pnas.1715997115. [Epub ahead of print] PubMed PMID: 29363593.

5. Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS. PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance. J Antimicrob Chemother. 2018 Jan 19. doi: 10.1093/jac/dkx531. [Epub ahead of print] PubMed PMID: 29360990.

6. Petrelli B, Weinberg J, Hicks GG. Effects of Prenatal Alcohol Exposure (PAE): Insights into FASD using PAE Mouse Models. Biochem Cell Biol. 2018 Jan 25. doi: 10.1139/bcb-2017-0280. [Epub ahead of print] PubMed PMID: 29370535.

Jan 22 Pubcrawler Hits:

1. Macdonald LC, Kim RY, Kurata HT, Fedida D. Probing the molecular basis of hERG drug block with unnatural amino acids. Sci Rep. 2018 Jan 10;8(1):289. doi: 10.1038/s41598-017-18448-x. PubMed PMID: 29321549; PubMed Central PMCID: PMC5762913.

2. Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S. Transmembrane Pickets onnect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell.  018 Jan 11;172(1-2):305-317.e10. doi: 10.1016/j.cell.2017.12.023. PubMed PMID: 29328918.

3. Bi C, Tham DKL, Perronnet C, Joshi B, Nabi IR, Moukhles H. The Oxidative Stress-Induced Increase in the Membrane Expression of the Water-Permeable Channel Aquaporin-4 in Astrocytes Is Regulated by Caveolin-1 Phosphorylation. Front Cell Neurosci. 2017 Dec 20;11:412. doi: 10.3389/fncel.2017.00412. eCollection 2017. PubMed PMID: 29326556; PubMed Central PMCID: PMC5742350.

4. Lussier AA, Morin AM, MacIsaac JL, Salmon J, Weinberg J, Reynolds JN, Pavlidis P, Chudley AE, Kobor MS. DNA methylation as a predictor of fetal alcohol spectrum disorder. Clin Epigenetics. 2018 Jan 12;10:5. doi: 10.1186/s13148-018-0439-6. eCollection 2018. PubMed PMID: 29344313; PubMed Central PMCID: PMC5767049.

5. Dalwadi U, Yip CK. Structural insights into the function of Elongator. Cell Mol Life Sci. 2018 Jan 13. doi: 10.1007/s00018-018-2747-6. [Epub ahead of print] Review. PubMed PMID: 29332244.

Jan 15 Pubcrawler Hits:

1. Linde C, Cleland JGF, Gold MR, Claude Daubert J, Tang ASL, Young JB, Sherfesee L, Abraham WT. The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. Eur J Heart Fail. 2018 Jan 4. doi: 10.1002/ejhf.1133. [Epub ahead of print] PubMed PMID: 29314424.

2. Macdonald SS, Patel A, Larmour VLC, Morgan-Lang C, Hallam SJ, Mark BL, WithersSG. Structural and mechanistic analysis of a β-glycoside phosphorylase identified by screening a metagenomic library. J Biol Chem. 2018 Jan 9. pii: jbc.RA117.000948. doi: 10.1074/jbc.RA117.000948. [Epub ahead of print] PubMed PMID: 29317495.

3. Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH. A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses. Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4. PubMed PMID: 29311608; PubMed Central PMCID: PMC5758616.

4. Lee-Sayer SSM, Maeshima N, Dougan MN, Dahiya A, Arif AA, Dosanjh M, Maxwell CA, Johnson P. Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells. Eur J Immunol. 2018 Jan 8. doi: 1002/eji.201747263. [Epub ahead of print] PubMed PMID: 29315518.

5. Solis N, Overall CM. Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS). Methods Mol Biol. 2018;1731:15-28. doi:10.1007/978-1-4939-7595-2_2. PubMed PMID: 29318539.

6. Grieco TM, Richman JM. Coordination of bilateral tooth replacement in the juvenile gecko is continuous with in ovo patterning. Evol Dev. 2018 Jan 10. doi: 1111/ede.12247. [Epub ahead of print] PubMed PMID: 29318754.

7. Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y. Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages. Sci Rep. 2018 Jan 9;8(1):155. doi: 10.1038/s41598-017-18547-9. PubMed PMID: 29317718.

Jan 8 Pubcrawler Hits:

1. Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. PubMed PMID: 29296696; PubMed Central PMCID: PMC5744055.

Jan 1 Pubcrawler Hits:

1. Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, Brömme D. Tanshinones: A novel class of ectosteric anti-resorptives. Br J Pharmacol. 2017 Dec 26. doi: 10.1111/bph.14133. [Epub ahead of print] PubMed PMID: 29278432.

2. Galibert M, Wartenberg M, Lecaille F, Saidi A, Mavel S, Joulin-Giet A, Korkmaz B, Brömme D, Aucagne V, Delmas AF, Lalmanach G. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. Eur J Med Chem. 2017 Dec 7;144:201-210. doi: 10.1016/j.ejmech.2017.12.012. [Epub ahead of print] PubMed PMID: 29272750.

3. Simard M, Underhill C, Hammond GL. Functional Implications of Corticosteroid-binding Globulin N-Glycosylation. J Mol Endocrinol. 2017 Dec 22. pii: JME-17-0234. doi: 10.1530/JME-17-0234. [Epub ahead of print] PubMed PMID: 29273683.

4. Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. 2017 Dec 19. pii: S0016-5085(17)36711-2. doi: 10.1053/j.gastro.2017.12.007. [Epub ahead of print] PubMed PMID: 29273451.


Dec 25 Pubcrawler Hits:

1. Klein T, Eckhard U, Dufour A, Solis N, Overall CM. Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification. Chem Rev. 2017 Dec 21. doi: 10.1021/acs.chemrev.7b00120. [Epub ahead of print] PubMed PMID: 29265812.

2. Urtatiz O, Samani AMV, Kopp JL, Van Raamsdonk CD. Rapid melanoma induction in mice expressing oncogenic Braf(V600E) using Mitf-cre. Pigment Cell Melanoma Res. 2017 Dec 20. doi: 10.1111/pcmr.12680. [Epub ahead of print] PubMed PMID: 29266793.

3. Raineki C, Ellis L, Weinberg J. Impact of adolescent stress on the expression of stress-related receptors in the hippocampus of animals exposed to alcohol prenatally. Hippocampus. 2017 Dec 18. doi: 10.1002/hipo.22823. [Epub ahead of print] PubMed PMID: 29251811.

Dec 18 Pubcrawler Hits:

1. Garner SRC, Castellanos MC, Baillie K, Lian T, Allan DW. Drosophila female-specific Ilp7 motoneurons are generated by Fruitless-dependent cell death in males and a double-assurance survival role for Transformer in females. Development. 2017 Dec 11. pii: dev.150821. doi: 10.1242/dev.150821. [Epub ahead of print] PubMed PMID: 29229771.

2. Chen CCL, Goyal P, Karimi MM, Abildgaard MH, Kimura H, Lorincz MC. H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2. Genome Res. 2017 Dec 11. doi: 10.1101/gr.224717.117. [Epub ahead of print] PubMed PMID: 29229671.

Dec 11 Pubcrawler Hits:

1. Ho JCH, Pawar SV, Hallam SJ, Yadav VG. An Improved Whole-Cell Biosensor for the Discovery of Lignin-Transforming Enzymes in Functional Metagenomic Screens. ACS Synth Biol. 2017 Dec 4. doi: 10.1021/acssynbio.7b00412. [Epub ahead of print] PubMed PMID: 29182267.

2. Gemmel M, Harmeyer D, Bögi E, Fillet M, Hill LA, Hammond GL, Charlier TD, Pawluski JL. Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam. Behav Brain Res. 2017 Dec 5. pii: S0166-4328(17)31601-7. doi: 10.1016/j.bbr.2017.11.038. [Epub ahead of print] PubMed PMID: 29203333.

3. Burian J, Thompson CJ. Regulatory genes coordinating antibiotic-induced changes in promoter activity and early transcriptional termination of the mycobacterial intrinsic resistance gene whiB7. Mol Microbiol. 2017 Dec 4. doi: 10.1111/mmi.13890. [Epub ahead of print] PubMed PMID: 29205551.

Dec 04 Pubcrawler Hits:

1. Martin WF, Bryant DA, Beatty JT. A physiological perspective on the origin and evolution of photosynthesis. FEMS Microbiol Rev. 2017 Nov 21. doi: 10.1093/femsre/fux056. [Epub ahead of print] PubMed PMID: 29177446.

2. Pachiadaki MG, Sintes E, Bergauer K, Brown JM, Record NR, Swan BK, Mathyer ME, Hallam SJ, Lopez-Garcia P, Takaki Y, Nunoura T, Woyke T, Herndl GJ, Stepanauskas R. Major role of nitrite-oxidizing bacteria in dark ocean carbon fixation. Science. 2017 Nov 4; 358(6366):1046-1051. doi: 10.1126/science.aan8260. PubMed PMID: 29170234.

3. Paik YK, Overall CM, Deutsch EW, Van Eyk JE, Omenn GS. Progress and Future Direction of Chromosome-Centric Human Proteome Project. J Proteome Res. 2017 Dec 1;16(12):4253-4258. doi: 10.1021/acs.jproteome.7b00734. PubMed PMID: 29191025.

4. Tal A, Greenberg D, Av-Gay Y, Golan-Tripto I, Feinstein Y, Ben-Shimol S, Dagan R, Goldbart AD. Nitric oxide inhalations in bronchiolitis: A pilot, randomized, double-blinded, controlled trial. Pediatr Pulmonol. 2017 Nov 27. doi: 10.1002/ppul.23905. [Epub ahead of print] PubMed PMID: 29178284.

Nov 27 Pubcrawler Hits:

1. Samarasekera GDNG, Auld VJ. C-terminal Src kinase (Csk) regulates the tricellular junction protein Gliotactin independent of Src. Mol Biol Cell. 2017 Nov 22. pii: mbc.E17-04-0251. doi: 10.1091/mbc.E17-04-0251. [Epub ahead of print] PubMed PMID: 29167383.

2. Hou P, Eldstrom J, Shi J, Zhong L, McFarland K, Gao Y, Fedida D, Cui J.Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening. Nat Commun. 2017 Nov 23;8(1):1730. doi: 10.1038/s41467-017-01911-8. PubMed PMID: 29167462.

3. Molday LL, Wahl D, Sarunic M, Molday RS. Localization and Functional Characterization of the p.Asn965Ser (N965S) ABCA4 Variant in Mice Reveal Pathogenic Mechanisms Underlying Stargardt Macular Degeneration. Hum Mol Genet. 2017 Nov 14. doi: 10.1093/hmg/ddx400. [Epub ahead of print] PubMed PMID: 29145636.

4. Na CH, Barbhuiya M, Kim MS, Verbruggen S, Eacker S, Pletnikova O, Troncoso J, Halushka M, Menschaert G, Overall C, Pandey A. Discovery of non-canonical translation initiation sites through mass spectrometric analysis of protein N-termini. Genome Res. 2017 Nov 21. pii: gr.226050.117. doi: 10.1101/gr.226050.117. [Epub ahead of print] PubMed PMID: 29162641.

Nov 20 Pubcrawler Hits:

1. Karunakaran S, Clee SM. Genetics of metabolic syndrome: potential clues from wild-derived inbred mouse strains. Physiol Genomics. 2017 Nov 10:physiolgenomics.00059.2017. doi: 10.1152/physiolgenomics.00059.2017. [Epub ahead of print] PubMed PMID: 29127221.

2. Hawley AK, Nobu MK, Wright JJ, Durno WE, Morgan-Lang C, Sage B, Schwientek P, Swan BK, Rinke C, Torres-Beltrán M, Mewis K, Liu WT, Stepanauskas R, Woyke T, Hallam SJ. Diverse Marinimicrobia bacteria may mediate coupled biogeochemical cycles along eco-thermodynamic gradients. Nat Commun. 2017 Nov 15;8(1):1507. doi: 10.1038/s41467-017-01376-9. PubMed PMID: 29142241.

3. Sofer Y, Nevo N, Vechoropulus M, Shefer G, Osher E, Landis N, Hammond GL, Stern N. Human sex hormone binding globulin does not provide metabolic protection against dysglycemia in mice. Endocr Connect. 2017 Nov 15. pii: EC-17-0240. doi: 10.1530/EC-17-0240. [Epub ahead of print] PubMed PMID: 29141991.

4. Freitas-Andrade M, She J, Bechberger J, Naus CC, Sin WC. Acute connexin43 temporal and spatial expression in response to ischemic stroke. J Cell Commun Signal. 2017 Nov 13. doi: 10.1007/s12079-017-0430-6. [Epub ahead of print] PubMed PMID: 29134540.

5. Tsui CKM, Wong D, Narula G, Gardy JL, Hsiao WWH, Av-Gay Y. Genome Sequences of the Mycobacterium tuberculosis H37Rv-ptkA Deletion Mutant and Its Parental Strain. Genome Announc. 2017 Nov 2;5(44). pii: e01156-17. doi: 10.1128/genomeA.01156-17. PubMed PMID: 29097456; PubMed Central PMCID: PMC5668532.

Nov 13 Pubcrawler Hits:

1. Cao Y, Wang X, Shi X, Clee SM, McGeer PL, Wolf MO, Orvig C. Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes. Angew Chem Int Ed Engl. 2017 Oct 18. doi: 10.1002/anie.201708529. [Epub ahead of print] PubMed PMID: 29045760.

2. Bowden CFM, Chan ACK, Li EJW, Arrieta AL, Eltis LD, Murphy MEP. Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin. J Biol Chem. 2017 Nov 6. pii: jbc.M117.806562. doi: 10.1074/jbc.M117.806562. [Epub ahead of print] PubMed PMID: 29109153.

3. Dou Y, Macdonald LC, Wu Y, Fedida D. The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues. Biophys J. 2017 Nov 7; 113(9):1979-1991. doi: 10.1016/j.bpj.2017.09.004. PubMed PMID: 29117522.

4. Page MM, Skovsø S, Cen H, Chiu AP, Dionne DA, Hutchinson DF, Lim GE, Szabat M, Flibotte S, Sinha S, Nislow C, Rodrigues B, Johnson JD. Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain. FASEB J. 2017 Nov 9. pii: fj.201700518R. doi: 10.1096/fj.201700518R. [Epub ahead of print] PubMed PMID: 29122848.

5. Lorincz MC, Schübeler D. Evidence for Converging DNA Methylation Pathways in Placenta and Cancer. Dev Cell. 2017 Nov 6; 43(3):257-258. doi: 10.1016/j.devcel.2017.10.009. PubMed PMID: 29112847.

6. Osseman Q, Gallucci L, Au S, Cazenave C, Berdance E, Blondot ML, Cassany A, Bégu D, Ragues J, Aknin C, Sominskaya I, Dishlers A, Rabe B, Anderson F, Panté N, Kann M. The chaperone dynein LL1 mediates cytoplasmic transport of empty and mature hepatitis B virus capsids. J Hepatol. 2017 Nov 4. pii: S0168-8278(17)32424-8. doi: 10.1016/j.jhep.2017.10.032. [Epub ahead of print] PubMed PMID: 29113909.

7. Gale RT, Li FKK, Sun T, Strynadka NCJ, Brown ED. B. subtilis LytR-CpsA-Psr Enzymes Transfer Wall Teichoic Acids from Authentic Lipid-Linked Substrates to Mature Peptidoglycan In Vitro. Cell Chem Biol. 2017 Oct 12. pii: S2451-9456(17)30350-1. doi: 10.1016/j.chembiol.2017.09.006. [Epub ahead of print] PubMed PMID: 29107701.

Nov 6 Pubcrawler Hits: 

1. Law S, Panwar P, Li J, Aguda AH, Jamroz A, Guido RVC, Brömme D. A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K. PLoS One. 2017 Oct 31;12(10):e0186869. doi: 10.1371/journal.pone.0186869. eCollection 2017. PubMed PMID: 29088253.

2. Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ. A compendium of geochemical information from the Saanich Inlet water column. Sci Data. 2017 Oct 31;4:170159. doi: 10.1038/sdata.2017.159. PubMed PMID: 29087371; PubMed Central PMCID: PMC5663218.

3. Hallam SJ, Torres-Beltrán M, Hawley AK. Monitoring microbial responses to ocean deoxygenation in a model oxygen minimum zone. Sci Data. 2017 Oct 31;4:170158. doi: 10.1038/sdata.2017.158. PubMed PMID: 29087370; PubMed Central PMCID: PMC5663219.

4. Hawley AK, Torres-Beltrán M, Zaikova E, Walsh DA, Mueller A, Scofield M, Kheirandish S, Payne C, Pakhomova L, Bhatia M, Shevchuk O, Gies EA, Fairley D, Malfatti SA, Norbeck AD, Brewer HM, Pasa-Tolic L, Del Rio TG, Suttle CA, Tringe S, Hallam SJ. A compendium of multi-omic sequence information from the Saanich Inlet water column. Sci Data. 2017 Oct 31;4:170160. doi: 10.1038/sdata.2017.160. PubMed PMID: 29087368; PubMed Central PMCID: PMC5663217.

5. Au HHT, Elspass VM, Jan E. Functional insights into the adjacent stem-loop in honey bee dicistroviruses that promotes IRES-mediated translation and viral infection. J Virol. 2017 Nov 1. pii: JVI.01725-17. doi: 10.1128/JVI.01725-17. [Epub ahead of print] PubMed PMID: 29093099.

1. Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu T, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel M, Pilarski LM, Simpson EM, Lange P, Allan DW, Maxwell CA. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. Elife. 2017 Oct 10;6. pii: e28672. doi: 10.7554/eLife.28672. [Epub ahead of print] PubMed PMID:

2. Lu L, Hogan-Cann AD, Globa AK, Lu P, Nagy JI, Bamji SX, Anderson CM. Astrocytes drive cortical vasodilatory signaling by activating endothelial NMDA receptors. J Cereb Blood Flow Metab. 2017 Jan 1:271678X17734100. doi: 10.1177/0271678X17734100. [Epub ahead of print] PubMed PMID: 29072857.

3. Carrel L, Brown CJ. When the Lyon(ized chromosome) roars: ongoing expression from an inactive X chromosome. Philos Trans R Soc Lond B Biol Sci. 2017 Nov 5;372(1733). pii: 20160355. doi: 10.1098/rstb.2016.0355. Review. PubMed PMID: 28947654; PubMed Central PMCID: PMC5627157.

4. Pang SS, Wijeyewickrema LC, Hor L, Tan S, Lameignere E, Conway EM, Blom AM, Mohlin FC, Liu X, Payne RJ, Whisstock JC, Pike RN. The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech. J Immunol. 2017 Oct 23. pii: ji1700158. doi: 10.4049/jimmunol.1700158. [Epub ahead of print] PubMed PMID: 29061764.

5. Crowe SA, Treusch AH, Forth M, Li J, Magen C, Canfield DE, Thamdrup B, Katsev S. Novel anammox bacteria and nitrogen loss from Lake Superior. Sci Rep. 2017 Oct 23; 7(1):13757. doi: 10.1038/s41598-017-12270-1. PubMed PMID: 29061974; PubMed Central PMCID: PMC5653767.

6. Neumann UH, Ho JSS, Chen S, Tam YYC, Cullis PR, Kieffer TJ. Lipid nanoparticle delivery of glucagon receptor siRNA improves glucose homeostasis in mouse models of diabetes. Mol Metab. 2017 Oct;6(10):1161-1172. doi: 10.1016/j.molmet.2017.06.012. Epub 2017 Jun 22. PubMed PMID: 29031717.

7. Nassif ME, Tang Y, Cleland JG, Abraham WT, Linde C, Gold MR, Young JB, Daubert JC, Sherfesee L, Schaber D, Tang ASL, Jones PG, Arnold SV, Spertus JA. Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials. Circ Heart Fail. 2017 Oct;10(10). pii: e004111. doi: 10.1161/CIRCHEARTFAILURE.117.004111. PubMed PMID: 29038172.

8. Strassert JFH, Karnkowska A, Hehenberger E, Del Campo J, Kolisko M, Okamoto N, Burki F, Janouškovec J, Poirier C, Leonard G, Hallam SJ, Richards TA, Worden AZ, Santoro AE, Keeling PJ. Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates. ISME J. 2017 Oct 10. doi: 10.1038/ismej.2017.167. [Epub ahead of print] PubMed PMID: 28994824.

9. Saez-Lopez C, Brianso-Llort L, Torres-Torrenteras J, Simó R, Hammond GL, Selva DM. Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox. Sci Rep. 2017 Sep 25;7(1):12284. doi: 10.1038/s41598-017-12509-x. PubMed PMID: 28947831; PubMed Central PMCID: PMC5612985.

10. Morse ZJ, Horwitz MS. Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset. Front Endocrinol (Lausanne). 2017 Sep 26;8:249. doi: 10.3389/fendo.2017.00249. eCollection 2017. Review. PubMed PMID: 29018409; PubMed
Central PMCID: PMC5623193.

11. Mouat IC, Morse ZJ, Jean-Baptiste VSE, Allanach JR, Horwitz MS. Fresh Ideas, Foundational Experiments (FIFE): Immunology and Diabetes 2016 FIFE Symposium. Front Endocrinol (Lausanne). 2017 Sep 19;8:238. doi: 10.3389/fendo.2017.00238.
eCollection 2017. PubMed PMID: 28974943; PubMed Central PMCID: PMC5610696.

12. Ramzy A, Mojibian M, Kieffer TJ. Insulin deficient mouse β-cells do not fully mature but can be remedied through insulin replacement by islet transplantation. Endocrinology. 2017 Sep 27. doi: 10.1210/en.2017-00263. [Epub ahead of print] PubMed PMID:  29029025.

13. Kieffer TJ. In Memoriam-John C. Brown, PhD, DSc, FRSC, 1938-2016: Discoverer of GIP and Motilin. Gastroenterology. 2017 Oct 5. pii: S0016-5085(17)36196-6. doi: 10.1053/j.gastro.2017.09.037. [Epub ahead of print] PubMed PMID: 28988915.

14. Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N. Beta cell replacement strategies for diabetes. J Diabetes Investig. 2017 Oct 6. doi: 10.1111/jdi.12758. [Epub ahead of print] PubMed PMID: 28984038.

15. D'souza AM, Neumann UH, Glavas MM, Kieffer TJ. The glucoregulatory actions of leptin. Mol Metab. 2017 May 4;6(9):1052-1065. doi: 10.1016/j.molmet.2017.04.011. eCollection 2017 Sep. Review. PubMed PMID: 28951828; PubMed Central PMCID:

16. Kumar P, Takayesu A, Abbasi U, Kalathottukaren MT, Abbina S, Kizhakkedathu JN, Straus SK. Antimicrobial Peptide-Polymer Conjugates with High Activity: Influence of Polymer Molecular Weight and Peptide Sequence on Antimicrobial Activity,
Proteolysis, and Biocompatibility. ACS Appl Mater Interfaces. 2017 Oct 19. doi: 10.1021/acsami.7b09471. [Epub ahead of print] PubMed PMID: 29019386.

17. Hadjesfandiari N, Weinhart M, Kizhakkedathu JN, Haag R, Brooks DE. Development of Antifouling and Bactericidal Coatings for Platelet Storage Bags Using Dopamine Chemistry. Adv Healthc Mater. 2017 Sep 29. doi: 10.1002/adhm.201700839. [Epub ahead of print] PubMed PMID: 28961393.

18. Mathew V, Tam AS, Milbury KL, Hofmann AK, Hughes CS, Morin GB, Loewen CJR, Stirling PC. Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress. J Cell Biol. 2017 Oct 4. pii: jcb.201612018. doi: 10.1083/jcb.201612018. [Epub ahead of print] PubMed PMID: 28978642.

19. Paik YK, Omenn GS, Lane L, Overall CM. Advances in the Chromosome-Centric Human Proteome Project: Looking to the Future. Expert Rev Proteomics. 2017 Oct 17. doi: 10.1080/14789450.2017.1394189. [Epub ahead of print] PubMed PMID:  29039980.

20. Schwenk JM, Omenn GS, Sun Z, Campbell DS, Baker MS, Overall CM, Aebersold R, Moritz RL, Deutsch EW. The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays. J Proteome Res. 2017 Oct 10. doi: 10.1021/acs.jproteome.7b00467. [Epub ahead of print] PubMed PMID: 28938075.

21. Paik YK, Omenn GS, Lane L, Overall CM. Advances in the Chromosome-Centric Human Proteome Project: Looking to the Future. Expert Rev Proteomics. 2017 Oct 17. doi: 10.1080/14789450.2017.1394189. [Epub ahead of print] PubMed PMID: 29039980.

22. Chu TLH, Connell M, Zhou L, He Z, Won JR, Rahavi SM, Chen H, Mohan P, Nemirovsky O, Fotovati A, Pujana MA, Reid GS, Nielsen TO, Pante N, Maxwell CA. Cell Cycle-dependent Tumor Engraftment and Migration are Enabled by Aurora A. Mol Cancer Res. 2017 Oct 9. pii: molcanres.0417.2017. doi: 10.1158/1541-7786.MCR-17-0417. [Epub ahead of print] PubMed PMID: 28993511.

23. Bernardes NE, Takeda AAS, Dreyer TR, Cupertino FB, Virgilio S, Pante N, Bertolini MC, Fontes MRM. Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by Importin-α. Biochem J. 2017 Oct 20. pii: BCJ20170654. doi: 10.1042/BCJ20170654. [Epub ahead of print] PubMed PMID: 29054975.

24. Fairchild MJ, Islam F, Tanentzapf G. Identification of genetic networks that act in the somatic cells of the testis to mediate the developmental program of spermatogenesis. PLoS Genet. 2017 Sep 28;13(9):e1007026. doi: 10.1371/journal.pgen.1007026. eCollection 2017 Sep. PubMed PMID: 28957323; PubMed Central PMCID: PMC5634645.

25. Liu Y, Wei J, Wong King Yuen SM, Sun B, Tang Y, Wang R, Van Petegem F, Chen SRW. CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression. PLoS One. 2017 Sep 29; 12(9):e0184177. doi: 10.1371/journal.pone.0184177.  eCollection 2017. PubMed PMID: 28961276; PubMed Central PMCID: PMC5621672.

26. Wong King Yuen SM, Campiglio M, Tung CC, Flucher BE, Van Petegem F. Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc Natl Acad Sci U S A. 2017 Oct 23. pii: 201708852. doi: 10.1073/pnas.1708852114. [Epub ahead of print] PubMed PMID: 29078335.

27. Vogl WA, Lyon K, Adams A, Piva M, Nassour V. The endoplasmic reticulum, calcium signaling and junction turnover in Sertoli cells. Reproduction. 2017 Oct 24. pii: REP-17-0281. doi: 10.1530/REP-17-0281. [Epub ahead of print] PubMed PMID: 29066527.

28. Lillie MA, Vogl WA, Raverty S, Haulena M, McLellan WA, Stenson GB, Shadwick RE. Controlling thoracic pressures in cetaceans during a breath-hold dive: importance of the diaphragm. J Exp Biol. 2017 Oct 1;220(Pt 19):3464-3477. doi: 10.1242/jeb.162289. PubMed PMID: 28978638.

29. Vogl WA, Petersen H, Adams A, Lillie MA, Shadwick RE. The Functional Anatomy of Nerves Innervating the Ventral Grooved Blubber of Fin Whales (Balaenoptera Physalus). Anat Rec (Hoboken). 2017 Nov; 300(11):1963-1972. doi: 10.1002/ar.23649. PubMed PMID: 28971627.

30. Vogl WA "Welcoming" Introduction to a Canadian Northwest Coast Thematic Papers Issue. Anat Rec (Hoboken). 2017 Nov; 300(11):1930-1934. doi: 10.1002/ar.23675. PubMed PMID: 28971625.

31. Nanji T, Liu X, Chew LH, Li FK, Biswas M, Yu ZQ, Lu S, Dong MQ, Du LL, Klionsky DJ, Yip CK. Conserved and unique features of the fission yeast core Atg1 complex. Autophagy. 2017 Oct 4:0. doi: 10.1080/15548627.2017.1382782. [Epub ahead
of print] PubMed PMID: 28976798.

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