The work of LSI’s Dr. Lindsay Eltis, Canada Research Chair in Microbial Catabolism and Biocatalysis, & Dr. Natalie Strynadka, has been featured by Science in the City (Vancouver), as Publication of the Week. The featured study provides insights into bacterial steroid catabolism and stands to facilitate the development of potential anti-tuberculosis therapeutics targeting IpdAB, a predicted CoA transferase (CoT) that has been implicated in the hydrolysis of a carbon-carbon bond.
Read the article here: IpdAB, a Virulence Factor in Mycobacterium Tuberculosis, Is a Cholesterol Ring-Cleaving Hydrolase
Image credit: Science in the City