Research Focus Teams

Rare Disease, Blood, Lung Disease

Research Interests

Bioengineering human-based models, gene therapies, inflammation and genetic diseases

Departments

School of Biomedical Engineering

Bio

Prof. Hedtrich obtained her PhD in Pharmaceutical Sciences from the Freie Universität Berlin in 2009. During her postdoc, she moved to the Ludwig-Maximilians-University in Munich and Tufts University in Boston, USA. She held one of the prestigious Johanna-Quandt-Professorships at the Berlin Institute of Health @ Charité in Berlin and was recently appointed as a Tier I Canada Research Chair in Human Disease Models at the School of Biomedical Engineering at the University of British Columbia.

Recent Publications

chevron_left
chevron_right

Unveiling tissue-specific transcriptional adaptations in iPSC-derived fibroblasts via co-culture systems

Lung tissue-optimized gene editing in human cystic fibrosis models following topical application of lipid nanoparticles

A hair-follicle reconstructed in vitro immunocompetent skin model for prediction of the sensitizing potential of chemicals

Spatially Defined Post-manufacturing Loading of Nanoparticles into Hydrogel-Forming Microneedles

Brownian dynamics simulation of the diffusion of rod-like nanoparticles in polymeric gels

Anti-Inflammatory Effects of Polyglycerol Sulfates and Natural Polyanions in Type 2 Inflammation

Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions

Lipid Nanoparticle-Mediated Hit-and-Run Approaches Yield Efficient and Safe In Situ Gene Editing in Human Skin

Extracellular Matrix Remodeling in Atopic Dermatitis Harnesses the Onset of an Asthmatic Phenotype and Is a Potential Contributor to the Atopic March