Lisa Osborne

Associate Professor

mail lisa.osborne@ubc.ca

call 604-822-6649

location_on 3506

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Research Focus Teams

Aging, COVID-19, Diabetes, Obesity, Chron's/Colitis, Multiple Sclerosis

Research Interests

Antiviral immunity, Germ free animals, Gut-brain axis, Intestinal epithelial cells, Microbiome, Mucosal Immunology, Multibiome, Neurodegenerative Diseases

Departments

Microbiology & Immunology

Bio

  • B.Sc. (Hons), University of Victoria
  • Ph.D., University of British Columbia
  • Postdoctoral Fellow, University of Pennsylvania, Weill Cornell Medical College
  • Currently Assistant Professor in the Dept. of Microbiology & Immunology, Director of the UBC Gnotobiotic Facility
  • Tier 2 Canada Research Chair in Host-Microbiome Interactions
  • Edmond J Safra Cancer Research Institute Irvington Postdoctoral Fellowship
  • Michael Smith Foundation for Health Research Senior Graduate Studentship
  • NSERC Doctoral Post-Graduate Scholarship
  • CIHR Strategic Training Program in Transplantation Research
  • Michael Smith Foundation for Health Research Junior Graduate Studentship

Recent Publications

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RANK drives structured intestinal epithelial expansion during pregnancy

The influence of aging and the microbiome in multiple sclerosis and other neurologic diseases

T4 Bacteriophage and E. coli Interaction in the Murine Intestine: A Prototypical Model for Studying Host-Bacteriophage Dynamics In Vivo

Virus induced dysbiosis promotes type 1 diabetes onset

Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis

Restriction of viral replication, rather than T cell immunopathology, drives lethality in MNV CR6-infected STAT1-deficient mice