Lindsay Eltis

Professor

mail lindsay.eltis@ubc.ca

call 604-822-0042

location_on 4509

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Research Focus Teams

Tuberculosis, Ecosystem Health

Research Interests

Antibiotic resistance, Enzymes, Gene Regulation and Expression, Genomics, Infectious diseases, Metabolomics, Microbiomics, Microorganisms, Steroids

Departments

Microbiology & Immunology

Bio

Lindsay obtained his PhD in Biochemistry in 1989 studying interactions between metalloproteins. His interest in bacterial catabolic enzymes and pathways began during his postdoctoral studies in Germany, when he studied enzymes involved in the degradation of polychlorinated biphenyls (PCBs). His primary research interest is bacterial enzymes and pathways responsible for the degradation of aromatic compounds and steroids. The author of over 140 peer-reviewed, original research papers, he uses a wide variety of approaches to gain novel insights into the molecular basis of these catabolic processes. His most significant contributions have changed the way we think about how important classes of enzymes work and how certain pathogens survive in their hosts. Lindsay's research has important implications for the development of novel biocatalysts for more sustainable processes as well as the development of novel therapeutics. In 2014, Lindsay was awarded a Canada Research Chair in Microbial Catabolism and Biocatalysis.

Recent Publications

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Laccase-catalyzed conversion of residual agricultural biomass to lignin-derived aromatic compounds

Recent advances in enzymes active on lignin-derived aromatic compounds

The catabolism of ethylene glycol by Rhodococcus jostii RHA1 and its dependence on mycofactocin

Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1

The catabolism of lignin-derived p-methoxylated aromatic compounds by Rhodococcus jostii RHA1

Tandem chemocatalysis and biological funneling to valorize lignin

The unusual convergence of steroid catabolic pathways in Mycobacterium abscessus