June 27, Pubcrawler Hits:

1. Basha G, Cottle AG, Pretheeban T, Chan KY, Witzigmann D, Young RN, Rossi FM, Cullis PR. Lipid Nanoparticle Mediated Silencing of Osteogenic Suppressor GNAS Leads to Osteogenic Differentiation of Mesenchymal Stem Cells In Vivo. Mol Ther. 2022 Jun 22:S1525-0016(22)00372-0. doi: 10.1016/j.ymthe.2022.06.012. Epub ahead of print. PMID: 35733339. https://pubmed.ncbi.nlm.nih.gov/35733339/

2. Zhigaltsev IV, Tam YYC, Kulkarni JA, Cullis PR. Synthesis and Characterization of Hybrid Lipid Nanoparticles Containing Gold Nanoparticles and a Weak Base Drug. Langmuir. 2022 Jun 16. doi: 10.1021/acs.langmuir.2c01221. Epub ahead of print. PMID: 35708310. https://pubmed.ncbi.nlm.nih.gov/35708310/

3. Brown JAR, Cui JH, Ling MYM, Gao EXC, Howe LJ, Teves SS. 43rd International Asilomar Chromatin, Chromosomes, and Epigenetics Conference. Biochem Cell Biol. 2022 Jun 21. doi: 10.1139/bcb-2022-0132. Epub ahead of print. PMID: 35728263. https://pubmed.ncbi.nlm.nih.gov/35728263/

4. Brind'Amour J, Lorincz MC. Profiling Histone Methylation in Low Numbers of Cells. Methods Mol Biol. 2022;2529:229-251. doi: 10.1007/978-1-0716-2481-4_11. PMID: 35733018. https://pubmed.ncbi.nlm.nih.gov/35733018/

5. Mothersole RG, Kolesnikov M, Chan ACK, Oduro E, Murphy MEP, Wolthers KR. Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry. 2022 Jun 22. doi: 10.1021/acs.biochem.2c00197. Epub ahead of print. PMID: 35732022. https://pubmed.ncbi.nlm.nih.gov/35732022/

6. Bell EM, Graves ML, Dean PM, Goodman TO, Roskelley CD. Modeling Collective Invasion and Single-Cell Mesenchymal Invasion in Three-Dimensional Matrigel-Collagen I Cultures. Methods Mol Biol. 2022;2508:79-99. doi: 10.1007/978-1-0716-2376-3_8. PMID: 35737235. https://pubmed.ncbi.nlm.nih.gov/35737235/

7. Nourbakhsh H, Adams A, Raverty S, Vogl AW, Haulena M, Skoretz SA. Microscopic Anatomy of the Upper Aerodigestive Tract in Harbour Seals (Phoca vitulina): Functional Adaptations to Swallowing. Anat Rec (Hoboken). 2022 Jun 19. doi: 10.1002/ar.25025. Epub ahead of print. PMID: 35719006. https://pubmed.ncbi.nlm.nih.gov/35719006/

8. Barvalia M, Harder KW. An End-to-End Workflow for Interrogating Tumor-Infiltrating Myeloid Cells Using Mass Cytometry. Methods Mol Biol. 2022;2508:147-168. doi: 10.1007/978-1-0716-2376-3_12. PMID: 35737239. https://pubmed.ncbi.nlm.nih.gov/35737239/

9. Flanagan K, Baradaran-Heravi A, Yin Q, Dao Duc K, Spradling AC, Greenblatt EJ. FMRP-dependent production of large dosage-sensitive proteins is highly conserved. Genetics. 2022 Jun 22:iyac094. doi: 10.1093/genetics/iyac094. Epub ahead of print. PMID: 35731217. https://pubmed.ncbi.nlm.nih.gov/35731217/

June 20, Pubcrawler Hits:

1. Grist SM, Bennewith KL, Cheung KC. Oxygen Measurement in Microdevices. Annu Rev Anal Chem (Palo Alto Calif). 2022 Jun 13;15(1):221-246. doi: 10.1146/annurev-anchem-061020-111458. PMID: 35696522. https://pubmed.ncbi.nlm.nih.gov/35696522/

June 13, Pubcrawler Hits:

1. Dhume SH, Connor SA, Mills F, Tari PK, Au-Yeung SHM, Karimi B, Oku S, Roppongi RT, Kawabe H, Bamji SX, Wang YT, Brose N, Jackson MF, Craig AM, Siddiqui TJ. Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits. Elife. 2022 Jun 6;11:e64742. doi: 10.7554/eLife.64742. PMID: 35662394; PMCID: PMC9170246. https://pubmed.ncbi.nlm.nih.gov/35662394/

2. Cikes D, Atanes P, Cronin SJF, Hagelkrüys A, Huang GC, Persaud SJ, Penninger JM. Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide. Sci Rep. 2022 Jun 7;12(1):9383. doi: 10.1038/s41598-022-13060-0. PMID: 35672347; PMCID: PMC9174263. https://pubmed.ncbi.nlm.nih.gov/35672347/

3. Rath M, Schwefel K, Malinverno M, Skowronek D, Leopoldi A, Pilz RA, Biedenweg D, Bekeschus S, Penninger JM, Dejana E, Felbor U. Contact-dependent signaling triggers tumor-like proliferation of CCM3 knockout endothelial cells in co-culture with wild-type cells. Cell Mol Life Sci. 2022 Jun 4;79(6):340. doi: 10.1007/s00018-022-04355-6. PMID: 35661927; PMCID: PMC9166869. https://pubmed.ncbi.nlm.nih.gov/35661927/

June 6, Pubcrawler Hits:

1. Rittberg R, Abraham N, Laskin J, Ho C. Hyper-Sensitive? Targeted Therapy With a Primed Immune System. J Thorac Oncol. 2022 Jun;17(6):734-736. doi: 10.1016/j.jtho.2022.03.003. PMID: 35623671. https://pubmed.ncbi.nlm.nih.gov/35623671/

2. Shimizu T, Aritoshi T, Beatty JT, Masuda T. Persulfide-Responsive Transcription Factor SqrR Regulates Gene Transfer and Biofilm Formation via the Metabolic Modulation of Cyclic di-GMP in Rhodobacter capsulatus. Microorganisms. 2022 Apr 26;10(5):908. doi: 10.3390/microorganisms10050908. PMID: 35630353; PMCID: PMC9143464. https://pubmed.ncbi.nlm.nih.gov/35630353/

3. Rankine-Wilson L, Rens C, Sahile HA, Av-Gay Y. Mycobacterium tuberculosis Infection of THP-1 Cells: A Model for High Content Analysis of Intracellular Growth and Drug Susceptibility. Methods Mol Biol. 2022;2427:73-82. doi: 10.1007/978-1-0716-1971-1_7. PMID: 35619026. https://pubmed.ncbi.nlm.nih.gov/35619026/

4. John L, Vernersson C, Kwon H, Elling U, Penninger JM, Mirazimi A. Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study. Pathogens. 2022 May 22;11(5):602. doi: 10.3390/pathogens11050602. PMID: 35631123; PMCID: PMC9144988. https://pubmed.ncbi.nlm.nih.gov/35631123/

5. Batlle D, Monteil V, Garreta E, Hassler L, Wysocki J, Chandar V, Schwartz RE, Mirazimi A, Montserrat N, Bader M, Penninger JM. Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity. Cell. 2022 May 26;185(11):1837-1839. doi: 10.1016/j.cell.2022.05.004. PMID: 35623327; PMCID: PMC9134488. https://pubmed.ncbi.nlm.nih.gov/35623327/

6. Yazdani-Ahmadabadi H, Felix DF, Yu K, Yeh HH, Luo HD, Khoddami S, Takeuchi LE, Alzahrani A, Abbina S, Mei Y, Fazli L, Grecov D, Lange D, Kizhakkedathu JN. Durable Surfaces from Film-Forming Silver Assemblies for Long-Term Zero Bacterial Adhesion without Toxicity. ACS Cent Sci. 2022 May 25;8(5):546-561. doi: 10.1021/acscentsci.1c01556. Epub 2022 Apr 27. PMID: 35647287; PMCID: PMC9136974. https://pubmed.ncbi.nlm.nih.gov/35647287/

May 30, Pubcrawler Hits:

1. Sheikh A, Lu J, Melese E, Seo JH, Abraham N. IL-7 induces type 2 cytokine response in lung ILC2s and regulates GATA3 and CD25 expression. J Leukoc Biol. 2022 May 23. doi: 10.1002/JLB.3AB1220-819RRR. Epub ahead of print. PMID: 35603486. https://pubmed.ncbi.nlm.nih.gov/35603486/

2. Canals Hernaez D, Hughes MR, Li Y, Mainero Rocca I, Dean P, Brassard J, Bell EM, Samudio I, Mes-Masson AM, Narimatsu Y, Clausen H, Blixt O, Roskelley CD, McNagny KM. Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models. Front Oncol. 2022 May 4;12:856424. doi: 10.3389/fonc.2022.856424. PMID: 35600398; PMCID: PMC9115113. https://pubmed.ncbi.nlm.nih.gov/35600398/

3. Young JW, Wason IS, Zhao Z, Kim S, Aoki H, Phanse S, Rattray DG, Foster LJ, Babu M, Duong van Hoa F. Development of a Method Combining Peptidiscs and Proteomics to Identify, Stabilize, and Purify a Detergent-Sensitive Membrane Protein Assembly. J Proteome Res. 2022 May 26. doi: 10.1021/acs.jproteome.2c00129. Epub ahead of print. PMID: 35616533. https://pubmed.ncbi.nlm.nih.gov/35616533/

4. Houfani AA, Foster LJ. Review of the Real and Sometimes Hidden Costs in Proteomics Experimental Workflows. Methods Mol Biol. 2022;2456:1-14. doi: 10.1007/978-1-0716-2124-0_1. PMID: 35612731. https://pubmed.ncbi.nlm.nih.gov/35612731/

5. Lu-Culligan A, Tabachnikova A, Pérez-Then E, Tokuyama M, Lee HJ, Lucas C, Silva Monteiro V, Miric M, Brache V, Cochon L, Muenker MC, Mohanty S, Huang J, Kang I, Dela Cruz C, Farhadian S, Campbell M, Yildirim I, Shaw AC, Ma S, Vermund SH, Ko AI, Omer SB, Iwasaki A. No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination. PLoS Biol. 2022 May 24;20(5):e3001506. doi: 10.1371/journal.pbio.3001506. PMID: 35609110; PMCID: PMC9129011. https://pubmed.ncbi.nlm.nih.gov/35609110/

May 23, Pubcrawler Hits:

1. Cheng MHY, Brimacombe CA, Verbeke R, Cullis PR. Exciting Times for Lipid Nanoparticles: How Canadian Discoveries Are Enabling Gene Therapies. Mol Pharm. 2022 May 18. doi: 10.1021/acs.molpharmaceut.2c00365. Epub ahead of print. PMID: 35583489. https://pubmed.ncbi.nlm.nih.gov/35583489/

2. Garreta E, Prado P, Stanifer ML, Monteil V, Marco A, Ullate-Agote A, Moya-Rull D, Vilas-Zornoza A, Tarantino C, Romero JP, Jonsson G, Oria R, Leopoldi A, Hagelkruys A, Gallo M, González F, Domingo-Pedrol P, Gavaldà A, Del Pozo CH, Hasan Ali O, Ventura-Aguiar P, Campistol JM, Prosper F, Mirazimi A, Boulant S, Penninger JM, Montserrat N. A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells. Cell Metab. 2022 May 10:S1550-4131(22)00136-X. doi: 10.1016/j.cmet.2022.04.009. Epub ahead of print. PMID: 35561674; PMCID: PMC9097013. https://pubmed.ncbi.nlm.nih.gov/35561674/

3. Lee R, Witherspoon L, Robinson M, Lee JH, Duffy SP, Flannigan R, Ma H. Automated rare sperm identification from low-magnification microscopy images of dissociated microsurgical testicular sperm extraction samples using deep learning. Fertil Steril. 2022 May 10:S0015-0282(22)00195-9. doi: 10.1016/j.fertnstert.2022.03.011. Epub ahead of print. PMID: 35562203. https://pubmed.ncbi.nlm.nih.gov/35562203/

May 16, Pubcrawler Hits:

1. Pawar SV, Hallam SJ, Yadav VG. Metagenomic discovery of a novel transaminase for valorization of monoaromatic compounds. RSC Adv. 2018 Jun 20;8(40):22490-22497. doi: 10.1039/c8ra02764a. PMID: 35539725; PMCID: PMC9081488. https://pubmed.ncbi.nlm.nih.gov/35539725/

2. Zuo M, Fettig NM, Bernier LP, Pössnecker E, Spring S, Pu A, Ma XI, Lee DS, Ward LA, Sharma A, Kuhle J, Sled JG, Pröbstel AK, MacVicar BA, Osborne LC, Gommerman JL, Ramaglia V. Age-dependent grey matter demyelination is associated with leptomeningeal neutrophil accumulation. JCI Insight. 2022 May 10:e158144. doi: 10.1172/jci.insight.158144. Epub ahead of print. PMID: 35536649. https://pubmed.ncbi.nlm.nih.gov/35536649/

3. Holguin-Cruz JA, Foster LJ, Gsponer J. Where protein structure and cell diversity meet. Trends Cell Biol. 2022 May 7:S0962-8924(22)00092-7. doi: 10.1016/j.tcb.2022.04.004. Epub ahead of print. PMID: 35537902. https://pubmed.ncbi.nlm.nih.gov/35537902/

May 9, Pubcrawler Hits:

1. Levy-Booth DJ, Navas LE, Fetherolf MM, Liu LY, Dalhuisen T, Renneckar S, Eltis LD, Mohn WW. Discovery of lignin-transforming bacteria and enzymes in thermophilic environments using stable isotope probing. ISME J. 2022 May 2. doi: 10.1038/s41396-022-01241-8. Epub ahead of print. PMID: 35501417. https://pubmed.ncbi.nlm.nih.gov/35501417/

2. Abbina S, La CC, Vappala S, Kalathottukaren MT, Abbasi U, Gill A, Smith SA, Haynes CA, Morrissey JH, Kizhakkedathu JN. Influence of Steric Shield on Biocompatibility and Antithrombotic Activity of Dendritic Polyphosphate Inhibitor. Mol Pharm. 2022 May 2. doi: 10.1021/acs.molpharmaceut.1c00934. Epub ahead of print. PMID: 35500201. https://pubmed.ncbi.nlm.nih.gov/35500201/

May 2, Pubcrawler Hits:

1. Melese ES, Franks E, Cederberg RA, Harbourne BT, Shi R, Wadsworth BJ, Collier JL, Halvorsen EC, Johnson F, Luu J, Oh MH, Lam V, Krystal G, Hoover SB, Raffeld M, Simpson RM, Unni AM, Lam WL, Lam S, Abraham N, Bennewith KL, Lockwood WW. CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development. Oncoimmunology. 2021 Dec 30;11(1):2010905. doi: 10.1080/2162402X.2021.2010905. PMID: 35481284; PMCID: PMC9038050. https://pubmed.ncbi.nlm.nih.gov/35481284/

2. Ask A, Eltringham-Smith L, Bhakta V, Donkor DA, Pryzdial ELG, Sheffield WP. Spotlight on animal models of acute traumatic coagulopathy: An update. Transfus Apher Sci. 2022 Mar 10:103412. doi: 10.1016/j.transci.2022.103412. Epub ahead of print. PMID: 35283031. https://pubmed.ncbi.nlm.nih.gov/35283031/

3. Feresten AH, Bhat JM, Yu AJ, Zapf R, Safi H, Au V, Flibotte S, Doell C, Moerman DG, Hawkins N, Rankin CH, Hutter H. ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans. Genetics. 2022 Apr 4;220(4):iyac024. doi: 10.1093/genetics/iyac024. PMID: 35143653; PMCID: PMC8982044. https://pubmed.ncbi.nlm.nih.gov/35143653/

Apr 25, Pubcrawler Hits:

1. Ramzy A, Edeer N, Baker RK, O'Dwyer S, Mojibian M, Verchere CB, Kieffer TJ. Insulin null ß-cells have a prohormone processing defect that is not reversed by AAV rescue of proinsulin expression. Endocrinology. 2022 Apr 18:bqac051. doi: 10.1210/endocr/bqac051. Epub ahead of print. PMID: 35435956. https://pubmed.ncbi.nlm.nih.gov/35435956/

2. Abdelilah-Seyfried S, Iruela-Arispe ML, Penninger JM, Tournier-Lasserve E, Vikkula M, Cleaver O. Recalibrating vascular malformations and mechanotransduction by pharmacological intervention. J Clin Invest. 2022 Apr 15;132(8):e160227. doi: 10.1172/JCI160227. PMID: 35426368; PMCID: PMC9012280. https://pubmed.ncbi.nlm.nih.gov/35426368/

Apr 18, Pubcrawler Hits:

1. Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ. Adult T-cells impair neonatal cardiac regeneration. Eur Heart J. 2022 Apr 13:ehac188. doi: 10.1093/eurheartj/ehac153. Epub ahead of print. PMID: 35417553. https://pubmed.ncbi.nlm.nih.gov/35417553/

Apr 11, Pubcrawler Hits:

1. Vardaki MZ, Georg Schulze H, Serrano K, Blades MW, Devine DV, F B Turner R. Assessing the quality of stored red blood cells using handheld Spatially Offset Raman spectroscopy with multisource correlation analysis. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Apr 1;276:121220. doi: 10.1016/j.saa.2022.121220. Epub ahead of print. PMID: 35395462. https://pubmed.ncbi.nlm.nih.gov/35395462/

Apr 4, Pubcrawler Hits:

1. Navas LE, Zahn M, Bajwa H, Grigg JC, Wolf ME, Chan ACK, Murphy MEP, McGeehan JE, Eltis LD. Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. J Biol Chem. 2022 Mar 25:101871. doi: 10.1016/j.jbc.2022.101871. Epub ahead of print. PMID: 35346686. https://pubmed.ncbi.nlm.nih.gov/35346686/

2. Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic. Nature. 2022 Mar 28. doi: 10.1038/s41586-022-04661-w. Epub ahead of print. PMID: 35344983. https://pubmed.ncbi.nlm.nih.gov/35344983/

3. Fedoretz-Maxwell BP, Shin CH, MacNeil GA, Worrall LJ, Park R, Strynadka NCJ, Walsby CJ, Warren JJ. The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorg Chem. 2022 Mar 29. doi: 10.1021/acs.inorgchem.2c00030. Epub ahead of print. PMID: 35347989. https://pubmed.ncbi.nlm.nih.gov/35347989/

Mar 28, Pubcrawler Hits:

1. Budzyński MA, Teves SS. System reset: topoisomerase 1 clears mitotic DNA for transcriptional memory. Trends Biochem Sci. 2022 Mar 17:S0968-0004(22)00064-0. doi: 10.1016/j.tibs.2022.03.005. Epub ahead of print. PMID: 35307259. https://pubmed.ncbi.nlm.nih.gov/35307259/

Mar 21, Pubcrawler Hits:

1. Tsai MS, Wang LC, Wu HL, Tzeng SF, Conway EM, Hsu SM, Chen SH. Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses. J Neuroinflammation. 2022 Mar 11;19(1):66. doi: 10.1186/s12974-022-02426-w. PMID: 35277184; PMCID: PMC8915510. https://pubmed.ncbi.nlm.nih.gov/35277184/

2. Labouta HI, Langer R, Cullis PR, Merkel OM, Prausnitz MR, Gomaa Y, Nogueira SS, Kumeria T. Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective. Drug Deliv Transl Res. 2022 Mar 15:1–8. doi: 10.1007/s13346-022-01146-1. Epub ahead of print. PMID: 35290656; PMCID: PMC8923087. https://pubmed.ncbi.nlm.nih.gov/35290656/

3. Van De Ven CJC, Laurenzi L, Arnold AC, Hallam SJ, Mayer KU. The nature of gas production patterns associated with methanol degradation in natural aquifer sediments: A microcosm study. J Contam Hydrol. 2022 Mar 8;247:103988. doi: 10.1016/j.jconhyd.2022.103988. Epub ahead of print. PMID: 35303484. https://pubmed.ncbi.nlm.nih.gov/35303484/

4. Mouat IC, Horwitz MS. Age-associated B cells in viral infection. PLoS Pathog. 2022 Mar 17;18(3):e1010297. doi: 10.1371/journal.ppat.1010297. PMID: 35298565; PMCID: PMC8929649. https://pubmed.ncbi.nlm.nih.gov/35298565/

5. Patil S, Dou Y, Kopp JL. Cell Type of Pancreatic Ductal Adenocarcinoma Origin: Implications for Prognosis and Clinical Outcomes. Visc Med. 2022 Feb;38(1):4-10. doi: 10.1159/000520946. Epub 2021 Dec 27. PMID: 35295896; PMCID: PMC8874250. https://pubmed.ncbi.nlm.nih.gov/35295896/

6. Qin J, Zhang J, Lin L, Haji-Ghassemi O, Lin Z, Woycechowsky KJ, Van Petegem F, Zhang Y, Yuchi Z. Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy. Elife. 2022 Mar 17;11:e75346. doi: 10.7554/eLife.75346. Epub ahead of print. PMID: 35297759. https://pubmed.ncbi.nlm.nih.gov/35297759/

7. Clephane K, O'Loughlin JI, Bodnar TS, Wilson MC, Stariha JT, Craig AN, Weinberg J, Brotto LA, Lorenz TK. Lack of Evidence for a Relationship Between Salivary CRP and Women's Sexual Desire: An Investigation Across Clinical and Healthy Samples. J Sex Med. 2022 Mar 13:S1743-6095(22)00583-5. doi: 10.1016/j.jsxm.2022.02.007. Epub ahead of print. PMID: 35296386. https://pubmed.ncbi.nlm.nih.gov/35296386/

8. Jayewickreme R, Mao T, Philbrick W, Kong Y, Treger RS, Lu P, Rakib T, Dong H, Dang-Lawson M, Guild WA, Lau TJ, Iwasaki A, Tokuyama M. Endogenous Retroviruses Provide Protection Against Vaginal HSV-2 Disease. Front Immunol. 2022 Jan 4;12:758721. doi: 10.3389/fimmu.2021.758721. PMID: 35058919; PMCID: PMC8764156. https://pubmed.ncbi.nlm.nih.gov/35058919/

Mar 14, Pubcrawler Hits:

1. Al-Riyami AZ, Burnouf T, Wood EM, Devine DV, Oreh A, Apelseth TO, Goel R, Bloch EM, van Den Berg K, Getshen M, Louw V, Ang AL, Lee CK, Rahimi-Levene N, Stramer SL, Vassallo R, Schulze TJ, Patidar GK, Pandey HC, Dubey R, Badawi M, Hindawi S, Meshi A, Matsushita T, Sorrentino E, Grubovic Rastvorceva RM, Bazin R, Vermeulen M, Nahirniak S, Tsang HC, Vrielink H, Triyono T, Addas-Carvalho M, Hećimović A, Torres OW, Mutindu SM, Bengtsson J, Dominguez D, Sayedahmed A, Hanisa Musa R, Gautam B, Herczenik E, So-Osman C; ISBT COVID-19 Convalescent Plasma Working Group. International Society of Blood Transfusion survey of experiences of blood banks and transfusion services during the COVID-19 pandemic. Vox Sang. 2022 Mar 8. doi: 10.1111/vox.13256. Epub ahead of print. PMID: 35262978. https://pubmed.ncbi.nlm.nih.gov/35262978/

2. Kieffer TJ. I. Progress Towards a Stem Cell Based Therapy for Diabetes. J Stem Cells Regen Med. 2021 Dec 30;17(2):61. doi: 10.46582/jsrm.1702010. PMID: 35250203; PMCID: PMC8866802. https://pubmed.ncbi.nlm.nih.gov/35250203/

3. Matthews K, Lamoureux ES, Myrand-Lapierre ME, Duffy SP, Ma H. Technologies for measuring red blood cell deformability. Lab Chip. 2022 Mar 10. doi: 10.1039/d1lc01058a. Epub ahead of print. PMID: 35266475. https://pubmed.ncbi.nlm.nih.gov/35266475/

Mar 7, Pubcrawler Hits:

1. Ng L, Li YX, Van Petegem F, Accili EA. Altered cyclic nucleotide-binding and pore opening in a diseased human HCN4 channel. Biophys J. 2022 Feb 24:S0006-3495(22)00184-9. doi: 10.1016/j.bpj.2022.02.035. Epub ahead of print. PMID: 35219649. https://pubmed.ncbi.nlm.nih.gov/35219649/

2. Xia B, Zhu R, Zhang H, Chen B, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Wang XD, Bromme D, Wang L, Wang X, Zhang D. Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice. Oxid Med Cell Longev. 2022 Feb 17;2022:3697067. doi: 10.1155/2022/3697067. PMID: 35222796; PMCID: PMC8872668. https://pubmed.ncbi.nlm.nih.gov/35222796/

3. Pattipeiluhu R, Arias-Alpizar G, Basha G, Chan KYT, Bussmann J, Sharp TH, Moradi MA, Sommerdijk N, Harris EN, Cullis PR, Kros A, Witzigmann D, Campbell F. Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System. Adv Mater. 2022 Feb 25:e2201095. doi: 10.1002/adma.202201095. Epub ahead of print. PMID: 35218106. https://pubmed.ncbi.nlm.nih.gov/35218106/

4. Yang ZF, Panwar P, McFarlane CR, Tuinte WE, Campiglio M, Van Petegem F. Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2120416119. doi: 10.1073/pnas.2120416119. Epub 2022 Mar 1. PMID: 35238659. https://pubmed.ncbi.nlm.nih.gov/35238659/

5. Omachi K, Kai H, Roberge M, Miner JH. NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough. iScience. 2022 Feb 8;25(3):103891. doi: 10.1016/j.isci.2022.103891. PMID: 35243249; PMCID: PMC8866893. https://pubmed.ncbi.nlm.nih.gov/35243249/

6. Tocheva EI. A picture is worth a thousand words: Direct in vivo visualization of the bacterial chromosome segregation protein, PopZ. J Mol Biol. 2022 Mar 1:167521. doi: 10.1016/j.jmb.2022.167521. Epub ahead of print. PMID: 35245499. https://pubmed.ncbi.nlm.nih.gov/35245499/

7. King DT, Serrano-Negrón JE, Zhu Y, Moore CL, Shoulders MD, Foster LJ, Vocadlo DJ. Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome. J Am Chem Soc. 2022 Mar 1. doi: 10.1021/jacs.1c10621. Epub ahead of print. PMID: 35230102. https://pubmed.ncbi.nlm.nih.gov/35230102/

Feb 28, Pubcrawler Hits:

1. Hadjesfandiari N, Serrano K, Levin E, Johal P, Feenstra S, Shih AW, Devine DV. Effect of modern infusion pumps on RBC quality. Transfusion. 2022 Feb 25. doi: 10.1111/trf.16833. Epub ahead of print. PMID: 35213738. https://pubmed.ncbi.nlm.nih.gov/35213738/

2. Zhang AMY, Chu KH, Daly BF, Ruiter T, Dou Y, Yang JCC, de Winter TJJ, Chhuor J, Wang S, Flibotte S, Zhao YB, Hu X, Li H, Rideout EJ, Schaeffer DF, Johnson JD, Kopp JL. Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics. Cancer Metab. 2022 Feb 21;10(1):5. doi: 10.1186/s40170-022-00282-z. PMID: 35189981; PMCID: PMC8862319. https://pubmed.ncbi.nlm.nih.gov/35189981/

3. Pelosi C, Constantinescu I, Son HH, Tinè MR, Kizhakkedathu JN, Wurm FR. Blood Compatibility of Hydrophilic Polyphosphoesters. ACS Appl Bio Mater. 2022 Feb 24. doi: 10.1021/acsabm.1c01210. Epub ahead of print. PMID: 35201742. https://pubmed.ncbi.nlm.nih.gov/35201742/

4. Millington JW, Biswas P, Chao C, Xia YH, Wat LW, Brownrigg GP, Sun Z, Basner-Collins PJ, Geltink RIK, Rideout EJ. A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms. Development. 2022 Feb 23:dev.200491. doi: 10.1242/dev.200491. Epub ahead of print. PMID: 35195254. https://pubmed.ncbi.nlm.nih.gov/35195254/

5. Bodnar TS, Mak DY, Hill LA, Ellis L, Yu W, Weinberg J. Modulatory role of prenatal alcohol exposure and adolescent stress on the response to arthritis challenge in adult female rats. EBioMedicine. 2022 Feb 17;77:103876. doi: 10.1016/j.ebiom.2022.103876. Epub ahead of print. PMID: 35183867. https://pubmed.ncbi.nlm.nih.gov/35183867/

6. Humbert PO, Pryjda TZ, Pranjic B, Farrell A, Fujikura K, de Matos Simoes R, Karim R, Kozieradzki I, Cronin SJF, Neely GG, Meyer TF, Hagelkruys A, Richardson HE, Penninger JM. TSPAN6 is a suppressor of Ras-driven cancer. Oncogene. 2022 Feb 19. doi: 10.1038/s41388-022-02223-y. Epub ahead of print. Erratum in: Oncogene. 2022 Mar 15;: PMID: 35184157. https://pubmed.ncbi.nlm.nih.gov/35184157/

Feb 21, Pubcrawler Hits:

1. Zhao H, Devine DV. The Missing Pieces to the Cold-Stored Platelet Puzzle. Int J Mol Sci. 2022 Jan 20;23(3):1100. doi: 10.3390/ijms23031100. PMID: 35163024; PMCID: PMC8835703. https://pubmed.ncbi.nlm.nih.gov/35163024/

2. Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M. Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs. Sci Transl Med. 2022 Feb 16;14(632):eabm7190. doi: 10.1126/scitranslmed.abm7190. Epub 2022 Feb 16. PMID: 35171649. https://pubmed.ncbi.nlm.nih.gov/35171649/

3. McAfee A, Metz BN, Milone JP, Foster LJ, Tarpy DR. Drone honey bees are disproportionately sensitive to abiotic stressors despite expressing high levels of stress response proteins. Commun Biol. 2022 Feb 17;5(1):141. doi: 10.1038/s42003-022-03092-7. PMID: 35177754. https://pubmed.ncbi.nlm.nih.gov/35177754/

4. Silva BC, Aguilar AP, Dutra L, Moon KM, Sébastien A, Foster LJ, Mendes TAO, de Oliveira Barros Ribon A. Proteomic Profiles of Staphylococcus aureus Strains Associated with Subclinical Bovine Mastitis. Curr Microbiol. 2022 Feb 12;79(4):101. doi: 10.1007/s00284-022-02796-7. PMID: 35150342. https://pubmed.ncbi.nlm.nih.gov/35150342/

Feb 14, Pubcrawler Hits:

1. Dixon-McDougall T, Brown CJ. Multiple distinct domains of human XIST are required to coordinate gene silencing and subsequent heterochromatin formation. Epigenetics Chromatin. 2022 Feb 4;15(1):6. doi: 10.1186/s13072-022-00438-7. PMID: 35120578; PMCID: PMC8815261. https://pubmed.ncbi.nlm.nih.gov/35120578/

2. Ludwig DS, Aronne LJ, Astrup A, de Cabo R, Cantley LC, Friedman MI, Heymsfield SB, Johnson JD, King JC, Krauss RM, Lieberman DE, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Ebbeling CB. Reply to A Drewnowski et al, O Devinsky, D A Booth and E L Gibson, and D J Millward. Am J Clin Nutr. 2022 Feb 9;115(2):595-597. doi: 10.1093/ajcn/nqab385. PMID: 35139162. https://pubmed.ncbi.nlm.nih.gov/35139162/

3. Skovsø S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, Li H, Modi H, Wildi JS, Botezelli JD, Noh HL, Suk S, Gablaski B, Bautista A, Kim R, Cras-Méneur C, Flibotte S, Sinha S, Luciani DS, Nislow C, Rideout EJ, Cytrynbaum EN, Kim JK, Bernal-Mizrachi E, Alonso LC, MacDonald PE, Johnson JD. Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance. Nat Commun. 2022 Feb 8;13(1):735. doi: 10.1038/s41467-022-28039-8. PMID: 35136059. https://pubmed.ncbi.nlm.nih.gov/35136059/

4. Dalwadi U, Mannar D, Zierhut F, Yip CK. Biochemical and Structural Characterization of Human Core Elongator and Its Subassemblies. ACS Omega. 2022 Jan 18;7(4):3424-3433. doi: 10.1021/acsomega.1c05719. PMID: 35128251; PMCID: PMC8811885. https://pubmed.ncbi.nlm.nih.gov/35128251/

Feb 7, Pubcrawler Hits:

1. Sharon AJ, Filyk HA, Fonseca NM, Simister RL, Filler RB, Yuen W, Hardman BK, Robinson HG, Seo JH, Rocha-Pereira J, Welch I, Neyts J, Wilen CB, Crowe SA, Osborne LC. Restriction of viral replication, rather than T cell immunopathology, drives lethality in MNV CR6-infected STAT1-deficient mice. J Virol. 2022 Feb 2:jvi0206521. doi: 10.1128/jvi.02065-21. Epub ahead of print. PMID: 35107369. https://pubmed.ncbi.nlm.nih.gov/35107369/

2. Bodnar TS, Lee C, Wong A, Rubin I, Wegener Parfrey L, Weinberg J. Evidence for long-lasting alterations in the fecal microbiota following prenatal alcohol exposure. Alcohol Clin Exp Res. 2022 Jan 31. doi: 10.1111/acer.14784. Epub ahead of print. PMID: 35102585. https://pubmed.ncbi.nlm.nih.gov/35102585/

3. Sahile HA, Williams DE, de Voogd NJ, Ko M, Andersen RJ, Av-Gay Y. Screening of diverse marine invertebrate extracts identified Lissoclinotoxin F, Discodermin B, and other anti-Mycobacterium tuberculosis active compounds. J Antibiot (Tokyo). 2022 Jan 28. doi: 10.1038/s41429-022-00507-9. Epub ahead of print. PMID: 35091665. https://pubmed.ncbi.nlm.nih.gov/35091665/

4. Borba RS, Hoover SE, Currie RW, Giovenazzo P, Guarna MM, Foster LJ, Zayed A, Pernal SF. Phenomic analysis of the honey bee pathogen-web and its dynamics on colony productivity, health and social immunity behaviors. PLoS One. 2022 Jan 31;17(1):e0263273. doi: 10.1371/journal.pone.0263273. PMID: 35100308; PMCID: PMC8803170. https://pubmed.ncbi.nlm.nih.gov/35100308/

Jan 31, Pubcrawler Hits:

1. Zhang H, Perez-Garcia P, Dierkes RF, Applegate V, Schumacher J, Chibani CM, Sternagel S, Preuss L, Weigert S, Schmeisser C, Danso D, Pleiss J, Almeida A, Höcker B, Hallam SJ, Schmitz RA, Smits SHJ, Chow J, Streit WR. The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity. Front Microbiol. 2022 Jan 5;12:803896. doi: 10.3389/fmicb.2021.803896. PMID: 35069509; PMCID: PMC8767016. https://pubmed.ncbi.nlm.nih.gov/35069509/

2. Gil KN, Vogl AW, Shadwick RE. Anatomical mechanism for protecting the airway in the largest animals on earth. Curr Biol. 2022 Jan 7:S0960-9822(21)01727-9. doi: 10.1016/j.cub.2021.12.040. Epub ahead of print. PMID: 35063119. https://pubmed.ncbi.nlm.nih.gov/35063119/

3. Hippmann AA, Schuback N, Moon KM, McCrow JP, Allen AE, Foster LF, Green BR, Maldonado MT. Proteomic analysis of metabolic pathways supports chloroplast-mitochondria cross-talk in a Cu-limited diatom. Plant Direct. 2022 Jan 20;6(1):e376. doi: 10.1002/pld3.376. PMID: 35079683; PMCID: PMC8777261. https://pubmed.ncbi.nlm.nih.gov/35079683/

Jan 24, Pubcrawler Hits:

1. Leatherdale A, Stukas S, Lei V, West HE, Campbell CJ, Hoiland RL, Cooper J, Wellington CL, Sekhon MS, Pryzdial ELG, Conway EM. Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality. Med Microbiol Immunol. 2022 Jan 16:1–12. doi: 10.1007/s00430-021-00725-2. Epub ahead of print. PMID: 35034207; PMCID: PMC8761108. https://pubmed.ncbi.nlm.nih.gov/35034207/

2. Gawish R, Starkl P, Pimenov L, Hladik A, Lakovits K, Oberndorfer F, Cronin SJ, Ohradanova-Repic A, Wirnsberger G, Agerer B, Endler L, Capraz T, Perthold JW, Cikes D, Koglgruber R, Hagelkruys A, Montserrat N, Mirazimi A, Boon L, Stockinger H, Bergthaler A, Oostenbrink C, Penninger JM, Knapp S. ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology. Elife. 2022 Jan 13;11:e74623. doi: 10.7554/eLife.74623. PMID: 35023830; PMCID: PMC8776253. https://pubmed.ncbi.nlm.nih.gov/35023830/

Jan 17, Pubcrawler Hits:

1. Sheikh A, Jackson J, Shim HB, Yau C, Seo JH, Abraham N. Selective dependence on IL-7 for antigen-specific CD8 T cell responses during airway influenza infection. Sci Rep. 2022 Jan 7;12(1):135. doi: 10.1038/s41598-021-03936-y. PMID: 34997007; PMCID: PMC8741933. https://pubmed.ncbi.nlm.nih.gov/34997007/

2. Park JY, Won HY, DiPalma DT, Kim HK, Kim TH, Li C, Sato N, Hong C, Abraham N, Gress RE, Park JH. In vivo availability of the cytokine IL-7 constrains the survival and homeostasis of peripheral iNKT cells. Cell Rep. 2022 Jan 11;38(2):110219. doi: 10.1016/j.celrep.2021.110219. PMID: 35021100. https://pubmed.ncbi.nlm.nih.gov/35021100/

3. Kirby MP, Stevenson C, Worrall LJ, Chen Y, Young C, Youm J, Strynadka NCJ, Allan DW, Jan E. The hinge region of the Israeli acute paralysis virus internal ribosome entry site directs ribosomal positioning, translational activity and virus infection. J Virol. 2022 Jan 12:JVI0133021. doi: 10.1128/JVI.01330-21. Epub ahead of print. PMID: 35019716. https://pubmed.ncbi.nlm.nih.gov/35019716/

4. Gentile F, Fernandez M, Ban F, Ton AT, Mslati H, Perez CF, Leblanc E, Yaacoub JC, Gleave J, Stern A, Wong B, Jean F, Strynadka N, Cherkasov A. Automated discovery of noncovalent inhibitors of SARS-CoV-2 main protease by consensus Deep Docking of 40 billion small molecules. Chem Sci. 2021 Nov 17;12(48):15960-15974. doi: 10.1039/d1sc05579h. PMID: 35024120; PMCID: PMC8672713. https://pubmed.ncbi.nlm.nih.gov/35024120/

5. Baradaran-Heravi A, Bauer CC, Pickles IB, Hosseini-Farahabadi S, Balgi AD, Choi K, Linley DM, Beech DJ, Roberge M, Bon RS. Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. J Biol Chem. 2022 Jan 6:101546. doi: 10.1016/j.jbc.2021.101546. Epub ahead of print. PMID: 34999117. https://pubmed.ncbi.nlm.nih.gov/34999117/

6. Shademani A, Jackson JK, Thompson CJ, Chiao M. Controlled and localized antibiotics delivery using magnetic-responsive beads for synergistic treatment of orthopedic infection. J Biomed Mater Res A. 2022 Jan 8. doi: 10.1002/jbm.a.37350. Epub ahead of print. PMID: 34997805. https://pubmed.ncbi.nlm.nih.gov/34997805/

7. Kuba K, Yamaguchi T, Penninger JM. Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19. Front Immunol. 2021 Dec 22;12:732690. doi: 10.3389/fimmu.2021.732690. PMID: 35003058; PMCID: PMC8727358. https://pubmed.ncbi.nlm.nih.gov/35003058/

8. Kokotović T, Lenartowicz EM, Langeslag M, Ciotu CI, Fell CW, Scaramuzza A, Fischer MJM, Kress M, Penninger JM, Nagy V. Transcription factor Mesenchyme Homeobox Protein 2 (MEOX2) modulates nociceptor function. FEBS J. 2022 Jan 13. doi: 10.1111/febs.16347. Epub ahead of print. PMID: 35029322. https://pubmed.ncbi.nlm.nih.gov/35029322/

9. Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A; CONCOR-1 Study Group, Arnold DM. Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nat Med. 2022 Jan 12:1. doi: 10.1038/s41591-021-01667-1. Epub ahead of print. Erratum for: Nat Med. 2021 Nov;27(11):2012-2024. PMID: 35022578; PMCID: PMC8753330. https://pubmed.ncbi.nlm.nih.gov/35022578/

Jan 10, Pubcrawler Hits:

1. Jun D, Zhang S, Grzędowski AJ, Mahey A, Beatty JT, Bizzotto D. Purification and preparation of Rhodobacter sphaeroides reaction centers for photocurrent measurements and atomic force microscopy characterization. STAR Protoc. 2021 Dec 16;3(1):101044. doi: 10.1016/j.xpro.2021.101044. PMID: 34977685; PMCID: PMC8689352. https://pubmed.ncbi.nlm.nih.gov/34977685/

2. Chadwick GL, Skennerton CT, Laso-Pérez R, Leu AO, Speth DR, Yu H, Morgan-Lang C, Hatzenpichler R, Goudeau D, Malmstrom R, Brazelton WJ, Woyke T, Hallam SJ, Tyson GW, Wegener G, Boetius A, Orphan VJ. Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea. PLoS Biol. 2022 Jan 5;20(1):e3001508. doi: 10.1371/journal.pbio.3001508. Epub ahead of print. PMID: 34986141. https://pubmed.ncbi.nlm.nih.gov/34986141/

3. Wright T, Vlok M, Shapira T, Olmstead AD, Jean F, Wolf MO. Photodynamic and Contact Killing Polymeric Fabric Coating for Bacteria and SARS-CoV-2. ACS Appl Mater Interfaces. 2022 Jan 3. doi: 10.1021/acsami.1c14178. Epub ahead of print. PMID: 34978405. https://pubmed.ncbi.nlm.nih.gov/34978405/

4. Price HR, Pang N, Kim H, Coughtrie MWH, Collier AC. Protective placental inflammatory and oxidative stress responses are attenuated in the context of twin pregnancy and chorioamnionitis in assisted reproduction. J Assist Reprod Genet. 2022 Jan 6. doi: 10.1007/s10815-021-02371-2. Epub ahead of print. PMID: 34988769. https://pubmed.ncbi.nlm.nih.gov/34988769/

5. Ito T, Kubiura-Ichimaru M, Murakami Y, Bogutz AB, Lefebvre L, Suetake I, Tajima S, Tada M. DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells. PLoS One. 2022 Jan 5;17(1):e0262277. doi: 10.1371/journal.pone.0262277. PMID: 34986190; PMCID: PMC8730390. https://pubmed.ncbi.nlm.nih.gov/34986190/

6. Mclean MA, Scoten OC, Yu W, Ye XY, Petrie J, Church PT, Soraisham AS, Mirea LS, Weinberg J, Synnes AR, O'Brien K, Grunau RE. Lower Maternal Chronic Physiological Stress and Better Child Behavior at 18 months: Follow-up of a Cluster Randomized Trial of NICU Family Integrated Care. J Pediatr. 2021 Dec 28:S0022-3476(21)01262-2. doi: 10.1016/j.jpeds.2021.12.055. Epub ahead of print. PMID: 34971651. https://pubmed.ncbi.nlm.nih.gov/34971651/

7. Sexton DL, Burgold S, Schertel A, Tocheva EI. Super-resolution confocal cryo-CLEM with cryo-FIB milling for in situ imaging of Deinococcus radiodurans. Curr Res Struct Biol. 2021 Dec 13;4:1-9. doi: 10.1016/j.crstbi.2021.12.001. PMID: 34977598; PMCID: PMC8688812. https://pubmed.ncbi.nlm.nih.gov/34977598/

8. Capraz T, Kienzl NF, Laurent E, Perthold JW, Föderl-Höbenreich E, Grünwald-Gruber C, Maresch D, Monteil V, Niederhöfer J, Wirnsberger G, Mirazimi A, Zatloukal K, Mach L, Penninger JM, Oostenbrink C, Stadlmann J. Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor. Elife. 2021 Dec 20;10:e73641. doi: 10.7554/eLife.73641. PMID: 34927585; PMCID: PMC8730730. https://pubmed.ncbi.nlm.nih.gov/34927585/

9. González-Cuesta M, Sidhu P, Ashmus RA, Males A, Proceviat C, Madden Z, Rogalski JC, Busmann JA, Foster LJ, García Fernández JM, Davies GJ, Ortiz Mellet C, Vocadlo DJ. Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications. J Am Chem Soc. 2022 Jan 5. doi: 10.1021/jacs.1c10504. Epub ahead of print. PMID: 34985906. https://pubmed.ncbi.nlm.nih.gov/34985906/

Jan 3, Pubcrawler Hits:

1. Juang LJ, Hur WS, Silva LM, Strilchuk AW, Francisco B, Leung J, Robertson MK, Groeneveld DJ, La Prairie B, Chun EM, Cap AP, Luyendyk JP, Palumbo JS, Cullis PR, Bugge TH, Flick MJ, Kastrup CJ. Suppression of fibrin(ogen)-driven pathologies through controlled knockdown by lipid nanoparticle delivery of siRNA. Blood. 2021 Dec 27:blood.2021014559. doi: 10.1182/blood.2021014559. Epub ahead of print. PMID: 34958662. https://pubmed.ncbi.nlm.nih.gov/34958662/

2. Molday RS, Garces FA, Scortecci JF, Molday LL. Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration. Prog Retin Eye Res. 2021 Dec 23:101036. doi: 10.1016/j.preteyeres.2021.101036. Epub ahead of print. PMID: 34954332.  https://pubmed.ncbi.nlm.nih.gov/34954332/

3. Arslanova A, Shafaattalab S, Ye K, Asghari P, Lin L, Kim B, Roston TM, Hove-Madsen L, Van Petegem F, Sanatani S, Moore E, Lynn F, Søndergaard M, Luo Y, Chen SRW, Tibbits GF. Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia. Curr Protoc. 2021 Dec;1(12):e320. doi: 10.1002/cpz1.320. PMID: 34958715. https://pubmed.ncbi.nlm.nih.gov/34958715/

4. Sugioka K. Symmetry-breaking of animal cytokinesis. Semin Cell Dev Biol. 2021 Dec 23:S1084-9521(21)00316-5. doi: 10.1016/j.semcdb.2021.12.008. Epub ahead of print. PMID: 34955355. https://pubmed.ncbi.nlm.nih.gov/34955355/

Dec 27, Pubcrawler Hits:

1. Jurczak A, Delay L, Barbier J, Simon N, Krock E, Sandor K, Agalave NM, Rudjito R, Wigerblad G, Rogóż K, Briat A, Miot-Noirault E, Martinez-Martinez A, Brömme D, Grönwall C, Malmström V, Klareskog L, Khoury S, Ferreira T, Labrum B, Deval E, Jiménez-Andrade JM, Marchand F, Svensson CI. Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity and ASIC3-dependent sensitization. Pain. 2021 Nov 19. doi: 10.1097/j.pain.0000000000002543. Epub ahead of print. PMID: 34924556. https://pubmed.ncbi.nlm.nih.gov/34924556/

2. Cen HH, Hussein B, Botezelli JD, Wang S, Zhang JA, Noursadeghi N, Jessen N, Rodrigues B, Timmons JA, Johnson JD. Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance. FASEB J. 2022 Jan;36(1):e22088. doi: 10.1096/fj.202100497RR. PMID: 34921686. https://pubmed.ncbi.nlm.nih.gov/34921686/

3. Urtatiz O, Haage A, Tanentzapf G, Van Raamsdonk CD. Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma. Elife. 2021 Dec 23;10:e71825. doi: 10.7554/eLife.71825. Epub ahead of print. PMID: 34939927. https://pubmed.ncbi.nlm.nih.gov/34939927/

4. Lussier AA, Bodnar TS, Weinberg J. Intersection of Epigenetic and Immune Alterations: Implications for Fetal Alcohol Spectrum Disorder and Mental Health. Front Neurosci. 2021 Dec 3;15:788630. doi: 10.3389/fnins.2021.788630. PMID: 34924946; PMCID: PMC8680672. https://pubmed.ncbi.nlm.nih.gov/34924946/

5. Richter A, Narula G, Rudolph I, Seidel RW, Wagner C, Av-Gay Y, Imming P. Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis. ChemMedChem. 2021 Dec 23:e202100733. doi: 10.1002/cmdc.202100733. Epub ahead of print. PMID: 34939744. https://pubmed.ncbi.nlm.nih.gov/34939744/

Dec 20, Pubcrawler Hits:

1. Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin YJ, Colwill K, Rathod B, Greenberg B, Gingras AC, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV. Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada. Transfusion. 2021 Dec 14. doi: 10.1111/trf.16772. Epub ahead of print. PMID: 34907536. https://pubmed.ncbi.nlm.nih.gov/34907536/

2. Rossi D, Lorenzini S, Pierantozzi E, Van Petegem F, Amadsun DO, Sorrentino V. Multiple regions of junctin drive interaction with calsequestrin-1 and localization at triads in skeletal muscle. J Cell Sci. 2021 Dec 16:jcs.259185. doi: 10.1242/jcs.259185. Epub ahead of print. PMID: 34913055. https://pubmed.ncbi.nlm.nih.gov/34913055/

3. Goel N, Philippe TJ, Chang J, Koblanski ME, Viau V. Cellular and serotonergic correlates of habituated neuroendocrine responses in male and female rats. Psychoneuroendocrinology. 2021 Nov 20;136:105599. doi: 10.1016/j.psyneuen.2021.105599. Epub ahead of print. PMID: 34891046. https://pubmed.ncbi.nlm.nih.gov/34891046/

Dec 13, Pubcrawler Hits:

1. Chen IS, Eldstrom J, Fedida D, Kubo Y. A novel ion conducting route besides the central pore in an inherited mutant of G-protein-gated inwardly rectifying K⁺ channel. J Physiol. 2021 Dec 8. doi: 10.1113/JP282430. Epub ahead of print. PMID: 34881429. https://pubmed.ncbi.nlm.nih.gov/34881429/

2. Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H. Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis. Transfusion. 2021 Dec 8. doi: 10.1111/trf.16757. Epub ahead of print. PMID: 34877683. https://pubmed.ncbi.nlm.nih.gov/34877683/

3. Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H. Assessing red blood cell deformability from microscopy images using deep learning. Lab Chip. 2021 Dec 7. doi: 10.1039/d1lc01006a. Epub ahead of print. PMID: 34874395. https://pubmed.ncbi.nlm.nih.gov/34874395/

4. Knuff-Janzen K, Serapio-Palacios A, McCoy J, Krekhno Z, Moon KM, Deng W, Foster LJ, Finlay BB. Quantitative proteomic screen identifies annexin A2 as a host target for Salmonella pathogenicity island-2 effectors SopD2 and PipB2. Sci Rep. 2021 Dec 8;11(1):23630. doi: 10.1038/s41598-021-02795-x. PMID: 34880286. https://pubmed.ncbi.nlm.nih.gov/34880286/

5. Flibotte S, Edgley M, Au V, Moerman DG. Whole Genome Sequencing identifies reciprocal translocation hT2(I;III) breakpoints. MicroPubl Biol. 2021 Dec 9;2021:10.17912/micropub.biology.000505. doi: 10.17912/micropub.biology.000505. PMID: 34909608; PMCID: PMC8662349. https://pubmed.ncbi.nlm.nih.gov/34909608/

6. Edgley ML, Flibotte S, Moerman DG. Sequenced Breakpoints of Crossover Suppressor/Inversion qC1. MicroPubl Biol. 2021 Nov 3;2021:10.17912/micropub.biology.000494. doi: 10.17912/micropub.biology.000494. PMID: 34746683; PMCID: PMC8567092. https://pubmed.ncbi.nlm.nih.gov/34746683/

7. Li-Leger E, Feichtinger R, Flibotte S, Holzkamp H, Schnabel R, Moerman DG. Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections. G3 (Bethesda). 2021 Dec 8;11(12):jkab328. doi: 10.1093/g3journal/jkab328. PMID: 34550348; PMCID: PMC8664450. https://pubmed.ncbi.nlm.nih.gov/34550348/

Dec 6, Pubcrawler Hits:

1. Kamanzi A, Gu Y, Tahvildari R, Friedenberger Z, Zhu X, Berti R, Kurylowicz M, Witzigmann D, Kulkarni JA, Leung J, Andersson J, Dahlin A, Höök F, Sutton M, Cullis PR, Leslie S. Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles. ACS Nano. 2021 Nov 29. doi: 10.1021/acsnano.1c04862. Epub ahead of print. PMID: 34843205. https://pubmed.ncbi.nlm.nih.gov/34843205/

2. Musso PY, Junca P, Gordon MD. A neural circuit linking two sugar sensors regulates satiety-dependent fructose drive in Drosophila. Sci Adv. 2021 Dec 3;7(49):eabj0186. doi: 10.1126/sciadv.abj0186. Epub 2021 Dec 1. PMID: 34851668; PMCID: PMC8635442. https://pubmed.ncbi.nlm.nih.gov/34851668/

3. Mette Frøbert A, Brohus M, Toews JNC, Round P, Fröbert O, Hammond GL, Overgaard MT. Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin. FEBS Open Bio. 2021 Dec 2. doi: 10.1002/2211-5463.13341. Epub ahead of print. PMID: 34855305. https://pubmed.ncbi.nlm.nih.gov/34855305/

4. Ramzy A, Thompson DM, Ward-Hartstonge KA, Ivison S, Cook L, Garcia RV, Loyal J, Kim PTW, Warnock GL, Levings MK, Kieffer TJ. Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes. Cell Stem Cell. 2021 Dec 2;28(12):2047-2061.e5. doi: 10.1016/j.stem.2021.10.003. PMID: 34861146. https://pubmed.ncbi.nlm.nih.gov/34861146/

5. Hoesli CA, Kieffer TJ. Pancreatic islets in bed with microvasculature-companions for life. Cell Rep Med. 2021 Nov 16;2(11):100454. doi: 10.1016/j.xcrm.2021.100454. PMID: 34841297; PMCID: PMC8607006. https://pubmed.ncbi.nlm.nih.gov/34841297/

6. Erener S, Ellis CE, Ramzy A, Glavas MM, O'Dwyer S, Pereira S, Wang T, Pang J, Bruin JE, Riedel MJ, Baker RK, Webber TD, Lesina M, Blüher M, Algül H, Kopp JL, Herzig S, Kieffer TJ. Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice. Cell Rep Med. 2021 Nov 11;2(11):100434. doi: 10.1016/j.xcrm.2021.100434. PMID: 34841287; PMCID: PMC8606901. https://pubmed.ncbi.nlm.nih.gov/34841287/

7. Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC. Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing. Nat Commun. 2021 Dec 2;12(1):7020. doi: 10.1038/s41467-021-27345-x. PMID: 34857746. https://pubmed.ncbi.nlm.nih.gov/34857746/

8. Overall CM. A Flickering Light at the End of the Pandemic Tunnel. J Proteome Res. 2021 Dec 3;20(12):5223-5226. doi: 10.1021/acs.jproteome.1c00866. PMID: 34856807. https://pubmed.ncbi.nlm.nih.gov/34856807/

9. Lussier AA, Bodnar TS, Moksa M, Hirst M, Kobor MS, Weinberg J. Prenatal Adversity Alters the Epigenetic Profile of the Prefrontal Cortex: Sexually Dimorphic Effects of Prenatal Alcohol Exposure and Food-Related Stress. Genes (Basel). 2021 Nov 9;12(11):1773. doi: 10.3390/genes12111773. PMID: 34828381; PMCID: PMC8622940. https://pubmed.ncbi.nlm.nih.gov/34828381/

Nov 29, Pubcrawler Hits: 

1. Mahto JK, Neetu N, Waghmode B, Kuatsjah E, Sharma M, Sircar D, Sharma AK, Tomar S, Eltis LD, Kumar P. Molecular insights into substrate recognition and catalysis by phthalate dioxygenase from Comamonas testosteroni. J Biol Chem. 2021 Nov 17:101416. doi: 10.1016/j.jbc.2021.101416. Epub ahead of print. PMID: 34800435. https://pubmed.ncbi.nlm.nih.gov/34800435/

2. Lincez PJ, Shanina I, Horwitz MS. Changes in MDA5 and TLR3 Sensing of the Same Diabetogenic Virus Result in Different Autoimmune Disease Outcomes. Front Immunol. 2021 Nov 5;12:751341. doi: 10.3389/fimmu.2021.751341. PMID: 34804036; PMCID: PMC8602094. https://pubmed.ncbi.nlm.nih.gov/34804036/

3. Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, An J, Saku A, Nukiwa R, Utsumi D, Kiso M, Yasuhara A, Poon VK, Chan CC, Fujino Y, Motoyama S, Nagata S, Penninger JM, Kamada H, Yuen KY, Kamitani W, Maeda K, Kawaoka Y, Yasutomi Y, Imai Y, Kuba K. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury. Nat Commun. 2021 Nov 23;12(1):6791. doi: 10.1038/s41467-021-27097-8. PMID: 34815389. https://pubmed.ncbi.nlm.nih.gov/34815389/

Nov 22, Pubcrawler Hits: 

1. Rapala J, Miller B, Garcia M, Dolan M, Bockman M, Hansson M, Russell DA, Garlena RA, Cresawn SG, Westbye AB, Beatty JT, Alvey RM, Bollivar DW. Genomic diversity of bacteriophages infecting Rhodobacter capsulatus and their relatedness to its gene transfer agent RcGTA. PLoS One. 2021 Nov 18;16(11):e0255262. doi: 10.1371/journal.pone.0255262. PMID: 34793465; PMCID: PMC8601537. https://pubmed.ncbi.nlm.nih.gov/34793465/

2. Phan HD, Longjohn MN, Gormley DJB, Smith RH, Dang-Lawson M, Matsuuchi L, Gold MR, Christian SL. CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles. J Immunol. 2021 Nov 12:ji2100025. doi: 10.4049/jimmunol.2100025. Epub ahead of print. PMID: 34772696. https://pubmed.ncbi.nlm.nih.gov/34772696/

3. Asghari P, Scriven DRL, Shahrasebi S, Moore EDW. RYR2 phosphomutants show that the tetramers and the junctional sarcoplasmic reticulum form a structural syncytium. J Gen Physiol. 2022 Sep 5;154(9):e2021ecc5. doi: 10.1085.jgp/2021ecc5. Epub 2021 Nov 12. PMID: 34766976. https://pubmed.ncbi.nlm.nih.gov/34766976/

4. Osborne LC. Protecting your gut feelings: How intestinal infections keep things moving. Neuron. 2021 Nov 17;109(22):3545-3547. doi: 10.1016/j.neuron.2021.10.037. PMID: 34793706. https://pubmed.ncbi.nlm.nih.gov/34793706/

5. Zhang J, Singh DP, Ko CY, Nikolaienko R, Wong King Yuen SM, Schwarz JA, Treinen LM, Tung CC, Rožman K, Svensson B, Aldrich CC, Zima AV, Thomas DD, Bers DM, Launikonis BS, Van Petegem F, Cornea RL. Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening. J Biol Chem. 2021 Nov 15:101412. doi: 10.1016/j.jbc.2021.101412. Epub ahead of print. PMID: 34793835. https://pubmed.ncbi.nlm.nih.gov/34793835/

6. Ma R, Haji-Ghassemi O, Ma D, Jiang H, Lin L, Xu T, Murayama T, Moussian B, Van Petegem F, Yuchi Z. Structural basis for diamide modulation of ryanodine receptor. J Gen Physiol. 2022 Sep 5;154(9):e2021ecc17. doi: 10.1085/jgp.2021ecc17. Epub 2021 Nov 12. PMID: 34766989. https://pubmed.ncbi.nlm.nih.gov/34766989/

7. Yu ACY, Volkers G, Jongkees SAK, Worrall LJ, Withers SG, Strynadka NCJ. Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases. Glycobiology. 2021 Nov 17:cwab094. doi: 10.1093/glycob/cwab094. Epub ahead of print. PMID: 34792586. https://pubmed.ncbi.nlm.nih.gov/34792586/

8. Sexton DL, Chen G, Kara Murdoch F, Hashimi A, Löffler FE, Tocheva EI. Ultrastructure of organohalide-respiring Dehalococcoidia revealed by cryo-electron tomography. Appl Environ Microbiol. 2021 Nov 17:AEM0190621. doi: 10.1128/AEM.01906-21. Epub ahead of print. PMID: 34788060. https://pubmed.ncbi.nlm.nih.gov/34788060/

9. Ctortecka C, Krššáková G, Stejskal K, Penninger JM, Mendjan S, Mechtler K, Stadlmann J. Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition. Mol Cell Proteomics. 2021 Nov 15:100177. doi: 10.1016/j.mcpro.2021.100177. Epub ahead of print. PMID: 34793982. https://pubmed.ncbi.nlm.nih.gov/34793982/

Nov 15, Pubcrawler Hits:

1. Lien KA, Dinshaw K, Nichols RJ, Cassidy-Amstutz C, Knight M, Singh R, Eltis LD, Savage DF, Stanley SA. A nanocompartment system contributes to defense against oxidative stress in Mycobacterium tuberculosis. Elife. 2021 Nov 9;10:e74358. doi: 10.7554/eLife.74358. Epub ahead of print. PMID: 34751132. https://pubmed.ncbi.nlm.nih.gov/34751132/

2. Gomez-Diaz C, Jonsson G, Schodl K, Deszcz L, Bestehorn A, Eislmayr K, Almagro J, Kavirayani A, Seida M, Fennell LM, Hagelkruys A, Kovarik P, Penninger JM, Ikeda F. The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains. iScience. 2021 Oct 8;24(11):103241. doi: 10.1016/j.isci.2021.103241. PMID: 34755089; PMCID: PMC8561004. https://pubmed.ncbi.nlm.nih.gov/34755089/

Nov 8, Pubcrawler Hits:

1. Vuong TV, Singh R, Eltis LD, Master ER. The Comparative Abilities of a Small Laccase and a Dye-Decoloring Peroxidase From the Same Bacterium to Transform Natural and Technical Lignins. Front Microbiol. 2021 Oct 18;12:723524. doi: 10.3389/fmicb.2021.723524. PMID: 34733245; PMCID: PMC8559727. https://pubmed.ncbi.nlm.nih.gov/34733245/

2. Fung SY, Lu HY, Sharma M, Sharma AA, Saferali A, Jia A, Abraham L, Klein T, Gold MR, Noterangelo LD, Overall CM, Turvey SE. MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness. Front Immunol. 2021 Oct 14;12:749794. doi: 10.3389/fimmu.2021.749794. PMID: 34721419; PMCID: PMC8552041. https://pubmed.ncbi.nlm.nih.gov/34721419/

3. Morse ZJ, Horwitz MS. Virus Infection Is an Instigator of Intestinal Dysbiosis Leading to Type 1 Diabetes. Front Immunol. 2021 Oct 15;12:751337. doi: 10.3389/fimmu.2021.751337. PMID: 34721424; PMCID: PMC8554326. https://pubmed.ncbi.nlm.nih.gov/34721424/

4. Grondin JM, Déjean G, Van Petegem F, Brumer H. Cell-surface xyloglucan recognition and hydrolysis by the human gut commensal Bacteroides uniformis. Appl Environ Microbiol. 2021 Nov 3:AEM0156621. doi: 10.1128/AEM.01566-21. Epub ahead of print. PMID: 34731054. https://pubmed.ncbi.nlm.nih.gov/34731054/

5. Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M. Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nat Methods. 2021 Nov;18(11):1304-1316. doi: 10.1038/s41592-021-01309-x. Epub 2021 Nov 1. PMID: 34725484. https://pubmed.ncbi.nlm.nih.gov/34725484/

Nov 1, Pubcrawler Hits:

1. Huang YH, Kuo CH, Peng IC, Chang YS, Tseng SH, Conway EM, Wu HL. Recombinant thrombomodulin domain 1 rescues pathological angiogenesis by inhibition of HIF-1α-VEGF pathway. Cell Mol Life Sci. 2021 Oct 27. doi: 10.1007/s00018-021-03950-3. Epub ahead of print. PMID: 34705054. https://pubmed.ncbi.nlm.nih.gov/34705054/

2. Traving SJ, Kellogg CTE, Ross T, McLaughlin R, Kieft B, Ho GY, Peña A, Krzywinski M, Robert M, Hallam SJ. Prokaryotic responses to a warm temperature anomaly in northeast subarctic Pacific waters. Commun Biol. 2021 Oct 22;4(1):1217. doi: 10.1038/s42003-021-02731-9. PMID: 34686760. https://pubmed.ncbi.nlm.nih.gov/34686760/

3. Wat LW, Chowdhury ZS, Millington JW, Biswas P, Rideout EJ. Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway. Elife. 2021 Oct 21;10:e72350. doi: 10.7554/eLife.72350. Epub ahead of print. PMID: 34672260. https://pubmed.ncbi.nlm.nih.gov/34672260/

4. Has C, Sayar SB, Zheng S, Chacón-Solano E, Condrat I, Yadav A, Roberge M, Laguzzi FL. Read-through for nonsense mutations in type XVII collagen deficient junctional epidermolysis bullosa. J Invest Dermatol. 2021 Oct 18:S0022-202X(21)02309-5. doi: 10.1016/j.jid.2021.09.018. Epub ahead of print. PMID: 34673051. https://pubmed.ncbi.nlm.nih.gov/34673051/

5. Yang X, Toyofuku WM, Scott MD. Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation. Arch Immunol Ther Exp (Warsz). 2021 Oct 22;69(1):30. doi: 10.1007/s00005-021-00634-5. PMID: 34677693; PMCID: PMC8536625. https://pubmed.ncbi.nlm.nih.gov/34677693/

Oct 25, Pubcrawler Hits:

1. Davidson AB, Holmden C, Nomosatryo S, Henny C, Francois R, Crowe SA. Cr Isotopes and the Engineered Attenuation of Cr(VI)-Rich Runoff. Environ Sci Technol. 2021 Oct 20. doi: 10.1021/acs.est.1c01714. Epub ahead of print. PMID: 34669373. https://pubmed.ncbi.nlm.nih.gov/34669373/

2. Omenn GS, Lane L, Overall CM, Paik YK, Cristea IM, Corrales FJ, Lindskog C, Weintraub S, Roehrl MHA, Liu S, Bandeira N, Srivastava S, Chen YJ, Aebersold R, Moritz RL, Deutsch EW. Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project. J Proteome Res. 2021 Oct 20. doi: 10.1021/acs.jproteome.1c00590. Epub ahead of print. PMID: 34670092. https://pubmed.ncbi.nlm.nih.gov/34670092/

Oct 18, Pubcrawler Hits:

1. Ma Y, Hadjesfandiari N, Doschak M, Devine D, Tonelli M, Unsworth L. Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma. Langmuir. 2021 Oct 13. doi: 10.1021/acs.langmuir.1c01783. Epub ahead of print. PMID: 34644097. https://pubmed.ncbi.nlm.nih.gov/34644097/

2. Eldstrom J, McAfee DA, Dou Y, Wang Y, Fedida D. ML277 regulates KCNQ1 single-channel amplitudes and kinetics, modified by voltage sensor state. J Gen Physiol. 2021 Dec 6;153(12):e202112969. doi: 10.1085/jgp.202112969. Epub 2021 Oct 12. PMID: 34636894. https://pubmed.ncbi.nlm.nih.gov/34636894/

3. Yu HB, Yang H, Allaire JM, Ma C, Graef FA, Mortha A, Liang Q, Bosman ES, Reid GS, Waschek JA, Osborne LC, Sokol H, Vallance BA, Jacobson K. Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2106634118. doi: 10.1073/pnas.2106634118. PMID: 34625492. https://pubmed.ncbi.nlm.nih.gov/34625492/

4. Mank JE, Rideout EJ. Developmental mechanisms of sex differences: from cells to organisms. Development. 2021 Oct 1;148(19):dev199750. doi: 10.1242/dev.199750. Epub 2021 Oct 14. PMID: 34647574. https://pubmed.ncbi.nlm.nih.gov/34647574/

5. Kokotović T, Langeslag M, Lenartowicz EM, Manion J, Fell CW, Alehabib E, Tafakhori A, Darvish H, Bellefroid EJ, Neely GG, Kress M, Penninger JM, Nagy V. PRDM12 Is Transcriptionally Active and Required for Nociceptor Function Throughout Life. Front Mol Neurosci. 2021 Sep 27;14:720973. doi: 10.3389/fnmol.2021.720973. PMID: 34646120; PMCID: PMC8502974. https://pubmed.ncbi.nlm.nih.gov/34646120/

Oct 11, Pubcrawler Hits:

1. Yeh HH, Yu K, Vappala S, Kalathottukaren MT, Abbina S, Luo HD, Grecov D, Kizhakkedathu JN. Rheological and clot microstructure evaluation of heparin neutralization by UHRA and protamine. J Mech Behav Biomed Mater. 2021 Sep 24;124:104851. doi: 10.1016/j.jmbbm.2021.104851. Epub ahead of print. PMID: 34600430. https://pubmed.ncbi.nlm.nih.gov/34600430/

2. Janssen SM, Lorincz MC. Interplay between chromatin marks in development and disease. Nat Rev Genet. 2021 Oct 4. doi: 10.1038/s41576-021-00416-x. Epub ahead of print. PMID: 34608297. https://pubmed.ncbi.nlm.nih.gov/34608297/

3. Scortecci JF, Molday LL, Curtis SB, Garces FA, Panwar P, Van Petegem F, Molday RS. Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun. 2021 Oct 8;12(1):5902. doi: 10.1038/s41467-021-26161-7. PMID: 34625547. https://pubmed.ncbi.nlm.nih.gov/34625547/

4. Pablos I, Machado Y, de Jesus HCR, Mohamud Y, Kappelhoff R, Lindskog C, Vlok M, Bell PA, Butler GS, Grin PM, Cao QT, Nguyen JP, Solis N, Abbina S, Rut W, Vederas JC, Szekely L, Szakos A, Drag M, Kizhakkedathu JN, Mossman K, Hirota JA, Jan E, Luo H, Banerjee A, Overall CM. Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL^pro substrate degradome. Cell Rep. 2021 Oct 26;37(4):109892. doi: 10.1016/j.celrep.2021.109892. Epub 2021 Oct 9. PMID: 34672947; PMCID: PMC8501228. https://pubmed.ncbi.nlm.nih.gov/34672947/

Oct 4, Pubcrawler Hits:

1. Hoffarth ER, Caddell Haatveit K, Kuatsjah E, MacNeil GA, Saroya S, Walsby CJ, Eltis LD, Houk KN, Garcia-Borràs M, Ryan KS. A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2012591118. doi: 10.1073/pnas.2012591118. PMID: 34580201. https://pubmed.ncbi.nlm.nih.gov/34580201/

2. Drayton M, Alford MA, Pletzer D, Haney EF, Machado Y, Luo HD, Overall CM, Kizhakkedathu JN, Hancock REW, Straus SK. Enzymatically releasable polyethylene glycol - Host defense peptide conjugates with improved activity and biocompatibility. J Control Release. 2021 Sep 28:S0168-3659(21)00514-9. doi: 10.1016/j.jconrel.2021.09.035. Epub ahead of print. PMID: 34597746. https://pubmed.ncbi.nlm.nih.gov/34597746/

3. Li T, Yu D, Oak HC, Zhu B, Wang L, Jiang X, Molday RS, Kriegstein A, Piao X. Phospholipid-flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure. EMBO J. 2021 Sep 29:e107915. doi: 10.15252/embj.2021107915. Epub ahead of print. PMID: 34585770. https://pubmed.ncbi.nlm.nih.gov/34585770/

Sep 27, Pubcrawler Hits:

1. Al Fayez N, Böttger R, Rouhollahi E, Cullis PR, Witzigmann D, Li SD. Improved Liver Delivery of Primaquine by Phospholipid-Free Small Unilamellar Vesicles with Reduced Hemolytic Toxicity. Mol Pharm. 2021 Sep 21. doi: 10.1021/acs.molpharmaceut.1c00520. Epub ahead of print. PMID: 34546758. https://pubmed.ncbi.nlm.nih.gov/34546758/

2. Arif AA, Huang YH, Freeman SA, Atif J, Dean P, Lai JCY, Blanchet MR, Wiegand KC, McNagny KM, Underhill TM, Gold MR, Johnson P, Roskelley CD. Inflammation-induced metastatic colonization of the lung is facilitated by HGF-secreting monocyte-derived macrophages. Mol Cancer Res. 2021 Sep 23:molcanres.0009.2021. doi: 10.1158/1541-7786.MCR-21-0009. Epub ahead of print. PMID: 34556524. https://pubmed.ncbi.nlm.nih.gov/34556524/

3. Glavas MM, Lee AY, Miao I, Yang F, Majid M, O'Dwyer SM, Kieffer TJ. Developmental Timing of High Fat Diet Exposure Impacts Glucose Homeostasis in Mice in a Sex-Specific Manner. Diabetes. 2021 Sep 20:db210310. doi: 10.2337/db21-0310. Epub ahead of print. PMID: 34544729. https://pubmed.ncbi.nlm.nih.gov/34544729/

4. Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Development of a novel, pan-variant aerosol intervention for COVID-19. bioRxiv [Preprint]. 2021 Sep 14:2021.09.14.459961. doi: 10.1101/2021.09.14.459961. PMID: 34545364; PMCID: PMC8452093. https://pubmed.ncbi.nlm.nih.gov/34545364/

5. Christopher JA, Stadler C, Martin CE, Morgenstern M, Pan Y, Betsinger CN, Rattray DG, Mahdessian D, Gingras AC, Warscheid B, Lehtiö J, Cristea IM, Foster LJ, Emili A, Lilley KS. Subcellular proteomics. Nat Rev Methods Primers. 2021;1:32. doi: 10.1038/s43586-021-00029-y. Epub 2021 Apr 29. PMID: 34549195; PMCID: PMC8451152. https://pubmed.ncbi.nlm.nih.gov/34549195/

6. Bixby MEF, Polinsky M, Scarlett R, Higo H, Common J, Hoover SE, Foster LJ, Zayed A, Cunningham M, Guarna MM. Impacts of COVID-19 on Canadian Beekeeping: Survey Results and a Profitability Analysis. J Econ Entomol. 2021 Sep 21:toab180. doi: 10.1093/jee/toab180. Epub ahead of print. PMID: 34545929. https://pubmed.ncbi.nlm.nih.gov/34545929/

Sep 20, Pubcrawler Hits:

1. Zhang XX, Young JW, Foster LJ, Duong F. Nanodisc-Based Proteomics Identify Caj1 as an Hsp40 with Affinity for Phosphatidic Acid Lipids. J Proteome Res. 2021 Sep 14. doi: 10.1021/acs.jproteome.1c00503. Epub ahead of print. PMID: 34519218. https://pubmed.ncbi.nlm.nih.gov/34519218/

2. Navas LE, Dexter G, Liu J, Levy-Booth D, Cho M, Jang SK, Mansfield SD, Renneckar S, Mohn WW, Eltis LD. Bacterial Transformation of Aromatic Monomers in Softwood Black Liquor. Front Microbiol. 2021 Sep 10;12:735000. doi: 10.3389/fmicb.2021.735000. PMID: 34566938; PMCID: PMC8461187. https://pubmed.ncbi.nlm.nih.gov/34566938/

3. Khoei S, Stokes A, Kieft B, Kadota P, Hallam SJ, Eskicioglu C. Biochar amendment rapidly shifts microbial community structure with enhanced thermophilic digestion activity. Bioresour Technol. 2021 Sep 1;341:125864. doi: 10.1016/j.biortech.2021.125864. Epub ahead of print. PMID: 34523581. https://pubmed.ncbi.nlm.nih.gov/34523581/

4. Basher ARMA, Mclaughlin RJ, Hallam SJ. Metabolic Pathway Prediction Using Non-Negative Matrix Factorization with Improved Precision. J Comput Biol. 2021 Sep 14. doi: 10.1089/cmb.2021.0258. Epub ahead of print. PMID: 34520674. https://pubmed.ncbi.nlm.nih.gov/34520674/

5. Ludwig DS, Aronne LJ, Astrup A, de Cabo R, Cantley LC, Friedman MI, Heymsfield SB, Johnson JD, King JC, Krauss RM, Lieberman DE, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Ebbeling CB. The carbohydrate-insulin model: a physiological perspective on the obesity pandemic. Am J Clin Nutr. 2021 Sep 13:nqab270. doi: 10.1093/ajcn/nqab270. Epub ahead of print. PMID: 34515299. https://pubmed.ncbi.nlm.nih.gov/34515299/

6. Durrer C, McKelvey S, Singer J, Batterham AM, Johnson JD, Gudmundson K, Wortman J, Little JP. A randomized controlled trial of pharmacist-led therapeutic carbohydrate and energy restriction in type 2 diabetes. Nat Commun. 2021 Sep 10;12(1):5367. doi: 10.1038/s41467-021-25667-4. PMID: 34508090. https://pubmed.ncbi.nlm.nih.gov/34508090/

7. Pereira S, Cline DL, Chan M, Chai K, Yoon JS, O'Dwyer SM, Ellis CE, Glavas MM, Webber TD, Baker RK, Erener S, Covey SD, Kieffer TJ. Role of myeloid cell leptin signaling in the regulation of glucose metabolism. Sci Rep. 2021 Sep 15;11(1):18394. doi: 10.1038/s41598-021-97549-0. PMID: 34526546. https://pubmed.ncbi.nlm.nih.gov/34526546/

8. Persaud R, Li SC, Chao JD, Forestieri R, Donohue E, Balgi AD, Zheng X, Chao JT, Yashiroda Y, Yoshimura M, Loewen CJR, Gingras AC, Boone C, Av-Gay Y, Roberge M, Andersen RJ. Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1. Cell Chem Biol. 2021 Sep 11:S2451-9456(21)00357-3. doi: 10.1016/j.chembiol.2021.07.017. Epub ahead of print. PMID: 34520745. https://pubmed.ncbi.nlm.nih.gov/34520745/

9. Popadynec M, Baradaran-Heravi A, Alford B, Cameron SA, Clinch K, Mason JM, Rendle PM, Zubkova OV, Gan Z, Liu H, Rebollo O, Whitfield DM, Yan F, Roberge M, Powell DA. Reducing the Toxicity of Designer Aminoglycosides as Nonsense Mutation Readthrough Agents for Therapeutic Targets. ACS Med Chem Lett. 2021 Aug 9;12(9):1486-1492. doi: 10.1021/acsmedchemlett.1c00349. PMID: 34531957; PMCID: PMC8436412. https://pubmed.ncbi.nlm.nih.gov/34531957/

Sep 13, Pubcrawler Hits:

1. Ganguly P, Madonsela L, Chao JT, Loewen CJR, O'Connor TP, Verheyen EM, Allan DW. A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation. PLoS Genet. 2021 Sep 7;17(9):e1009774. doi: 10.1371/journal.pgen.1009774. Epub ahead of print. PMID: 34492006. https://pubmed.ncbi.nlm.nih.gov/34492006/

2. Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A; CONCOR-1 Study Group, Arnold DM. Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nat Med. 2021 Sep 9. doi: 10.1038/s41591-021-01488-2. Epub ahead of print. PMID: 34504336. https://pubmed.ncbi.nlm.nih.gov/34504336/

3. Xue J, Purushotham P, Acheson JF, Ho R, Zimmer J, McFarlane C, Van Petegem F, Martone PT, Samuels AL. Functional characterization of a cellulose synthase, CtCESA1, from the marine red alga Calliarthron tuberculosum (Corallinales). J Exp Bot. 2021 Sep 10:erab414. doi: 10.1093/jxb/erab414. Epub ahead of print. PMID: 34505622. https://pubmed.ncbi.nlm.nih.gov/34505622/

4. Llongueras JP, Das S, De Waele J, Capulzini L, Sorgente A, Van Petegem F, Bosmans F. Biophysical Investigation of Sodium Channel Interaction with β-Subunit Variants Associated with Arrhythmias. Bioelectricity. 2020 Sep 1;2(3):269-278. doi: 10.1089/bioe.2020.0030. Epub 2020 Sep 16. PMID: 34476357; PMCID: PMC8370339. https://pubmed.ncbi.nlm.nih.gov/34476357/

5. Ho KYL, Khadilkar RJ, Carr RL, Tanentzapf G. A gap-junction-mediated, calcium-signaling network controls blood progenitor fate decisions in hematopoiesis. Curr Biol. 2021 Aug 31:S0960-9822(21)01131-3. doi: 10.1016/j.cub.2021.08.027. Epub ahead of print. PMID: 34480855. https://pubmed.ncbi.nlm.nih.gov/34480855/

Sep 6, Pubcrawler Hits:

1. Harandi-Zadeh S, Boycott C, Beetch M, Yang T, Martin BJE, Ren K, Kwasniak A, Dupuis JH, Lubecka K, Yada RY, Howe LJ, Stefanska B. Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells. Antioxidants (Basel). 2021 Jul 30;10(8):1232. doi: 10.3390/antiox10081232. PMID: 34439480; PMCID: PMC8388921. https://pubmed.ncbi.nlm.nih.gov/34439480/

2. Workman SD, Day J, Farha MA, El Zahed SS, Bon C, Brown ED, Organ MG, Strynadka NCJ. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 2. doi: 10.1021/acs.jmedchem.1c00941. Epub ahead of print. PMID: 34473495. https://pubmed.ncbi.nlm.nih.gov/34473495/

3. Rathinaswamy MK, Dalwadi U, Fleming KD, Adams C, Stariha JTB, Pardon E, Baek M, Vadas O, DiMaio F, Steyaert J, Hansen SD, Yip CK, Burke JE. Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation. Sci Adv. 2021 Aug 27;7(35):eabj4282. doi: 10.1126/sciadv.abj4282. PMID: 34452907. https://pubmed.ncbi.nlm.nih.gov/34452907/

4. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T, Juhász G, Karantza V, Kraft C, Kroemer G, Ktistakis NT, Kumar S, Lopez-Otin C, Macleod KF, Madeo F, Martinez J, Meléndez A, Mizushima N, Münz C, Penninger JM, Perera RM, Piacentini M, Reggiori F, Rubinsztein DC, Ryan KM, Sadoshima J, Santambrogio L, Scorrano L, Simon HU, Simon AK, Simonsen A, Stolz A, Tavernarakis N, Tooze SA, Yoshimori T, Yuan J, Yue Z, Zhong Q, Galluzzi L, Pietrocola F. Autophagy in major human diseases. EMBO J. 2021 Aug 30:e108863. doi: 10.15252/embj.2021108863. Epub ahead of print. PMID: 34459017. https://pubmed.ncbi.nlm.nih.gov/34459017/

5. Berger CS, Laroche J, Maaroufi H, Martin H, Moon KM, Landry CR, Foster LJ, Aubin-Horth N. The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions. Parasit Vectors. 2021 Aug 28;14(1):436. doi: 10.1186/s13071-021-04933-w. PMID: 34454597; PMCID: PMC8400842. https://pubmed.ncbi.nlm.nih.gov/34454597/

Aug 30, Pubcrawler Hits:

1. Kizhakkedathu JN, Conway EM. Biomaterial and cellular implants:foreign surfaces where immunity and coagulation meet. Blood. 2021 Aug 20:blood.2020007209. doi: 10.1182/blood.2020007209. Epub ahead of print. PMID: 34415324. https://pubmed.ncbi.nlm.nih.gov/34415324/

2. Round JW, Robeck LD, Eltis LD. An Integrative Toolbox for Synthetic Biology in Rhodococcus. ACS Synth Biol. 2021 Aug 24. doi: 10.1021/acssynbio.1c00292. Epub ahead of print. PMID: 34428025. https://pubmed.ncbi.nlm.nih.gov/34428025/

3. Palia P, Adams A, Sriram A, Vogl AW. Cortactin knockdown results in disruption of basal TBCs and alters turnover of Sertoli cell ESs in R. norvegicus. Biol Reprod. 2021 Aug 23:ioab161. doi: 10.1093/biolre/ioab161. Epub ahead of print. PMID: 34426822. https://pubmed.ncbi.nlm.nih.gov/34426822/

4. Tropini C. How the Physical Environment Shapes the Microbiota. mSystems. 2021 Aug 24:e0067521. doi: 10.1128/mSystems.00675-21. Epub ahead of print. PMID: 34427510. https://pubmed.ncbi.nlm.nih.gov/34427510/

Aug 23, Pubcrawler Hits:

1. Stanley M, Ghosh B, Weiss ZF, Christiaanse J, Gordon MD. Mechanisms of lactic acid gustatory attraction in Drosophila. Curr Biol. 2021 Aug 23;31(16):3525-3537.e6. doi: 10.1016/j.cub.2021.06.005. Epub 2021 Jun 30. PMID: 34197729. https://pubmed.ncbi.nlm.nih.gov/34197729/

2. Andriessen VC, Lightbourne M, Flippo C, Faucz FR, Delaney A, Hannah-Shmouni F, Hammond GL, Stratakis CA. Homozygous SHBG Variant (rs6258) Linked to Gonadotropin-Independent Precocious Puberty in a Young Girl. J Endocr Soc. 2021 Jul 19;5(10):bvab125. doi: 10.1210/jendso/bvab125. PMID: 34405127; PMCID: PMC8364343. https://pubmed.ncbi.nlm.nih.gov/34405127/

3. Scalzo RL, Foright RM, Hull SE, Knaub LA, Johnson-Murguia S, Kinanee F, Kaplan J, Houck JA, Johnson G, Sharp RR, Gillen AE, Jones KL, Zhang AMY, Johnson JD, MacLean PS, Reusch JEB, Wright-Hobart S, Wellberg EA. Breast cancer endocrine therapy promotes weight gain with distinct adipose tissue effects in lean and obese female mice. Endocrinology. 2021 Aug 19:bqab174. doi: 10.1210/endocr/bqab174. Epub ahead of print. PMID: 34410380. https://pubmed.ncbi.nlm.nih.gov/34410380/

4. Erwin SR, Bristow BN, Sullivan KE, Kendrick RM, Marriott B, Wang L, Clements J, Lemire AL, Jackson J, Cembrowski MS. Spatially patterned excitatory neuron subtypes and projections of the claustrum. Elife. 2021 Aug 16;10:e68967. doi: 10.7554/eLife.68967. PMID: 34397382; PMCID: PMC8367382. https://pubmed.ncbi.nlm.nih.gov/34397382/

Aug 16, Pubcrawler Hits:

1. Iworima DG, Rieck S, Kieffer TJ. Process parameter development for the scaled generation of stem cell-derived pancreatic endocrine cells. Stem Cells Transl Med. 2021 Aug 13. doi: 10.1002/sctm.21-0161. Epub ahead of print. PMID: 34387389. https://pubmed.ncbi.nlm.nih.gov/34387389/

2. Siren EMJ, Luo HD, Tam F, Montgomery A, Enns W, Moon H, Sim L, Rey K, Guan Q, Wang JJ, Wardell CM, Monajemi M, Mojibian M, Levings MK, Zhang ZJ, Du C, Withers SG, Choy JC, Kizhakkedathu JN. Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers. Nat Biomed Eng. 2021 Aug 9. doi: 10.1038/s41551-021-00777-y. Epub ahead of print. PMID: 34373602. https://pubmed.ncbi.nlm.nih.gov/34373602/

3. Kurashina M, Wang J, Lin J, Lee KK, Johal A, Mizumoto K. Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans. Elife. 2021 Aug 13;10:e66011. doi: 10.7554/eLife.66011. PMID: 34388088. https://pubmed.ncbi.nlm.nih.gov/34388088/

4. Brotto LA, Zdaniuk B, Chivers ML, Jabs F, Grabovac A, Lalumière ML, Weinberg J, Schonert-Reichl KA, Basson R. A randomized trial comparing group mindfulness-based cognitive therapy with group supportive sex education and therapy for the treatment of female sexual interest/arousal disorder. J Consult Clin Psychol. 2021 Jul;89(7):626-639. doi: 10.1037/ccp0000661. PMID: 34383535. https://pubmed.ncbi.nlm.nih.gov/34383535/

5. Hoffmann D, Mereiter S, Jin Oh Y, Monteil V, Elder E, Zhu R, Canena D, Hain L, Laurent E, Grünwald-Gruber C, Klausberger M, Jonsson G, Kellner MJ, Novatchkova M, Ticevic M, Chabloz A, Wirnsberger G, Hagelkruys A, Altmann F, Mach L, Stadlmann J, Oostenbrink C, Mirazimi A, Hinterdorfer P, Penninger JM. Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites. EMBO J. 2021 Aug 10:e108375. doi: 10.15252/embj.2021108375. Epub ahead of print. PMID: 34375000. https://pubmed.ncbi.nlm.nih.gov/34375000/

6. McAfee A, Tarpy DR, Foster LJ. Queen honey bees exhibit variable resilience to temperature stress. PLoS One. 2021 Aug 11;16(8):e0255381. doi: 10.1371/journal.pone.0255381. PMID: 34379669; PMCID: PMC8357134. https://pubmed.ncbi.nlm.nih.gov/34379669/

Aug 9, Pubcrawler Hits:

1. van der Meel R, Chen S, Zaifman J, Kulkarni JA, Zhang XRS, Tam YK, Bally MB, Schiffelers RM, Ciufolini MA, Cullis PR, Tam YYC. Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery. Small. 2021 Aug 1:e2103025. doi: 10.1002/smll.202103025. Epub ahead of print. PMID: 34337865. https://pubmed.ncbi.nlm.nih.gov/34337865/

2. Zhao X, Khatir B, Mirshahidi K, Yu K, Kizhakkedathu JN, Golovin K. Macroscopic Evidence of the Liquidlike Nature of Nanoscale Polydimethylsiloxane Brushes. ACS Nano. 2021 Aug 2. doi: 10.1021/acsnano.1c04386. Epub ahead of print. PMID: 34339162. https://pubmed.ncbi.nlm.nih.gov/34339162/

3. Rathinaswamy MK, Fleming KD, Dalwadi U, Pardon E, Harris NJ, Yip CK, Steyaert J, Burke JE. HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases. Structure. 2021 Jul 30:S0969-2126(21)00252-5. doi: 10.1016/j.str.2021.07.002. Epub ahead of print. PMID: 34348129. https://pubmed.ncbi.nlm.nih.gov/34348129/

Aug 2, Pubcrawler Hits:

1. Yip D, Accili E. Kinetic modelling of voltage-dependent gating in funny channels. Prog Biophys Mol Biol. 2021 Jul 23:S0079-6107(21)00090-0. doi: 10.1016/j.pbiomolbio.2021.07.009. Epub ahead of print. PMID: 34310984. https://pubmed.ncbi.nlm.nih.gov/34310984/

2. Wolf ME, Hinchen DJ, DuBois JL, McGeehan JE, Eltis LD. Cytochromes P450 in the biocatalytic valorization of lignin. Curr Opin Biotechnol. 2021 Jul 21;73:43-50. doi: 10.1016/j.copbio.2021.06.022. Epub ahead of print. PMID: 34303185. https://pubmed.ncbi.nlm.nih.gov/34303185/

3. Wardman JF, Rahfeld P, Liu F, Morgan-Lang C, Sim L, Hallam SJ, Withers SG. Discovery and Development of Promiscuous O-Glycan Hydrolases for Removal of Intact Sialyl T-Antigen. ACS Chem Biol. 2021 Jul 26. doi: 10.1021/acschembio.1c00316. Epub ahead of print. PMID: 34309358. https://pubmed.ncbi.nlm.nih.gov/34309358/

4. Johnson JD. On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes. Diabetologia. 2021 Jul 22. doi: 10.1007/s00125-021-05505-4. Epub ahead of print. PMID: 34296322. https://pubmed.ncbi.nlm.nih.gov/34296322/

5. Yu K, Alzahrani A, Khoddami S, Cheng JTJ, Mei Y, Gill A, Luo HD, Haney EF, Hilpert K, Hancock REW, Lange D, Kizhakkedathu JN. Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background. ACS Appl Mater Interfaces. 2021 Jul 30. doi: 10.1021/acsami.1c07515. Epub ahead of print. PMID: 34328312. https://pubmed.ncbi.nlm.nih.gov/34328312/

6. Amenyogbe N, Adu-Gyasi D, Enuameh Y, Asante KP, Konadu DG, Kaali S, Dosoo D, Panigrahi P, Kollmann TR, Mohn WW, Owusu-Agyei S. Bacterial and Fungal Gut Community Dynamics Over the First 5 Years of Life in Predominantly Rural Communities in Ghana. Front Microbiol. 2021 Jul 6;12:664407. doi: 10.3389/fmicb.2021.664407. PMID: 34295315; PMCID: PMC8290483. https://pubmed.ncbi.nlm.nih.gov/34295315/

7. Ng KM, Tropini C. Visualization of Gut Microbiota-host Interactions via Fluorescence In Situ Hybridization, Lectin Staining, and Imaging. J Vis Exp. 2021 Jul 9;(173). doi: 10.3791/62646. PMID: 34309601. https://pubmed.ncbi.nlm.nih.gov/34309601/

8. McAfee A, Milone JP, Metz B, McDermott E, Foster LJ, Tarpy DR. Honey bee queen health is unaffected by contact exposure to pesticides commonly found in beeswax. Sci Rep. 2021 Jul 26;11(1):15151. doi: 10.1038/s41598-021-94554-1. PMID: 34312437; PMCID: PMC8313582. https://pubmed.ncbi.nlm.nih.gov/34312437/

July 26, Pubcrawler Hits:

1. Hoiland RL, Ainslie PN, Wellington CL, Cooper J, Stukas S, Thiara S, Foster D, Fergusson N, Conway EM, Menon DK, Gooderham PA, Hirsch-Reinshagen V, Griesdale D, Sekhon M. Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post-Cardiac Arrest. Circ Res. 2021 Jul 21. doi: 10.1161/CIRCRESAHA.121.319157. Epub ahead of print. PMID: 34287000. https://pubmed.ncbi.nlm.nih.gov/34287000/

2. Schubert P, Chen Z, Bhakta V, Culibrk B, Wambolt R, Sheffield WP, Devine DV, McTaggart K. Cold-stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality. Transfusion. 2021 Jul;61 Suppl 1:S131-S143. doi: 10.1111/trf.16540. PMID: 34269454. https://pubmed.ncbi.nlm.nih.gov/34269454/

3. Ramzy A, Kieffer TJ. Altered islet prohormone processing: A cause or consequence of diabetes? Physiol Rev. 2021 Jul 19. doi: 10.1152/physrev.00008.2021. Epub ahead of print. PMID: 34280055. https://pubmed.ncbi.nlm.nih.gov/34280055/

4. Woll KA, Van Petegem F. Calcium Release Channels: Structure and Function of IP3 Receptors and Ryanodine Receptors. Physiol Rev. 2021 Jul 19. doi: 10.1152/physrev.00033.2020. Epub ahead of print. PMID: 34280054. https://pubmed.ncbi.nlm.nih.gov/34280054/

5. Baek M, DiMaio F, Anishchenko I, Dauparas J, Ovchinnikov S, Lee GR, Wang J, Cong Q, Kinch LN, Schaeffer RD, Millán C, Park H, Adams C, Glassman CR, DeGiovanni A, Pereira JH, Rodrigues AV, van Dijk AA, Ebrecht AC, Opperman DJ, Sagmeister T, Buhlheller C, Pavkov-Keller T, Rathinaswamy MK, Dalwadi U, Yip CK, Burke JE, Garcia KC, Grishin NV, Adams PD, Read RJ, Baker D. Accurate prediction of protein structures and interactions using a three-track neural network. Science. 2021 Jul 15:eabj8754. doi: 10.1126/science.abj8754. Epub ahead of print. PMID: 34282049. https://pubmed.ncbi.nlm.nih.gov/34282049/

6. Morisaki I, Shiraishi H, Fujinami H, Shimizu N, Hikida T, Arai Y, Kobayashi T, Hanada R, Penninger JM, Fujiki M, Hanada T. Modeling a human CLP1 mutation in mouse identifies an accumulation of tyrosine pre-tRNA fragments causing pontocerebellar hypoplasia type 10. Biochem Biophys Res Commun. 2021 Jul 14;570:60-66. doi: 10.1016/j.bbrc.2021.07.036. Epub ahead of print. PMID: 34273619. https://pubmed.ncbi.nlm.nih.gov/34273619/

July 19, Pubcrawler Hits:

1. Deretic N, Bolger-Munro M, Choi K, Abraham L, Gold MR. The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse. Front Cell Dev Biol. 2021 Jul 9;9:647063. doi: 10.3389/fcell.2021.647063. PMID: 34336818; PMCID: PMC8318000. https://pubmed.ncbi.nlm.nih.gov/34336818/

2. Kolic J, Johnson JD. Promises and pitfalls of beta cell-replacement therapies. Nat Metab. 2021 Jul 12. doi: 10.1038/s42255-021-00433-4. Epub ahead of print. PMID: 34253907. https://pubmed.ncbi.nlm.nih.gov/34253907/

3. Wong AKO, Young BP, Loewen CJR. Ist2 recruits the lipid transporters Osh6/7 to ER-PM contacts to maintain phospholipid metabolism. J Cell Biol. 2021 Sep 6;220(9):e201910161. doi: 10.1083/jcb.201910161. Epub 2021 Jul 14. PMID: 34259806. https://pubmed.ncbi.nlm.nih.gov/34259806/

4. Feller FM, Wöhlbrand L, Holert J, Schnaars V, Elsner L, Mohn WW, Rabus R, Philipp B. Proteome, bioinformatic and functional analyses reveal a distinct and conserved metabolic pathway for bile salt degradation in the Sphingomonadaceae. Appl Environ Microbiol. 2021 Jul 14:AEM0098721. doi: 10.1128/AEM.00987-21. Epub ahead of print. PMID: 34260303. https://pubmed.ncbi.nlm.nih.gov/34260303/

July 12, Pubcrawler Hits:

1. Xia J, Accili EA. Regulation of sinoatrial funny channels by cyclic nucleotides: From adrenaline and I_K2 to direct binding of ligands to protein subunits. Prog Biophys Mol Biol. 2021 Jul 5:S0079-6107(21)00070-5. doi: 10.1016/j.pbiomolbio.2021.06.010. Epub ahead of print. PMID: 34237319. https://pubmed.ncbi.nlm.nih.gov/34237319/

2. Beetch M, Boycott C, Harandi-Zadeh S, Yang T, Martin BJE, Dixon-McDougall T, Ren K, Gacad A, Dupuis JH, Ullmer M, Lubecka K, Yada RY, Brown CJ, Howe LJ, Stefanska B. Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells. J Nutr Biochem. 2021 Jul 6:108815. doi: 10.1016/j.jnutbio.2021.108815. Epub ahead of print. PMID: 34242723. https://pubmed.ncbi.nlm.nih.gov/34242723/

3. Glavas MM, Hui Q, Miao I, Yang F, Erener S, Prentice KJ, Wheeler MB, Kieffer TJ. Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats. Sci Rep. 2021 Jul 7;11(1):14032. doi: 10.1038/s41598-021-93409-z. PMID: 34234216; PMCID: PMC8263808. https://pubmed.ncbi.nlm.nih.gov/34234216/

4. Harris NJ, Jenkins ML, Dalwadi U, Fleming KD, Nam SE, Parsons MAH, Yip CK, Burke JE. Biochemical insight into novel Rab-GEF activity of the mammalian TRAPPIII complex. J Mol Biol. 2021 Jul 3:167145. doi: 10.1016/j.jmb.2021.167145. Epub ahead of print. PMID: 34229011. https://pubmed.ncbi.nlm.nih.gov/34229011/

5. Teves S. Embracing my roots. Science. 2021 Jul 2;373(6550):126. doi: 10.1126/science.373.6550.126. PMID: 34210889. https://pubmed.ncbi.nlm.nih.gov/34210889/

6. Bennet TJ, Randhawa A, Hua J, Cheung KC. Airway-On-A-Chip: Designs and Applications for Lung Repair and Disease. Cells. 2021 Jun 26;10(7):1602. doi: 10.3390/cells10071602. PMID: 34206722. https://pubmed.ncbi.nlm.nih.gov/34206722/

7. Skinnider MA, Foster LJ. Meta-analysis defines principles for the design and analysis of co-fractionation mass spectrometry experiments. Nat Methods. 2021 Jul;18(7):806-815. doi: 10.1038/s41592-021-01194-4. Epub 2021 Jul 1. PMID: 34211188. https://pubmed.ncbi.nlm.nih.gov/34211188/

8. Squair JW, Skinnider MA, Gautier M, Foster LJ, Courtine G. Prioritization of cell types responsive to biological perturbations in single-cell data with Augur. Nat Protoc. 2021 Jun 25. doi: 10.1038/s41596-021-00561-x. Epub ahead of print. PMID: 34172974. https://pubmed.ncbi.nlm.nih.gov/34172974/

9. Skinnider MA, Rogalski J, Tigchelaar S, Manouchehri N, Prudova A, Jackson AM, Nielsen K, Jeong J, Chaudhary S, Shortt K, Gallagher-Kurtzke Y, So K, Fong A, Gupta R, Okon EB, Rizzuto MA, Dong K, Streijger F, Belanger L, Ritchie L, Tsang A, Christie S, Mac-Thiong JM, Bailey C, Ailon T, Charest-Morin R, Dea N, Wilson JR, Dhall S, Paquette S, Street J, Fisher CG, Dvorak MF, Shannon C, Borchers C, Balshaw R, Foster LJ, Kwon BK. Proteomic Portraits Reveal Evolutionarily Conserved and Divergent Responses to Spinal Cord Injury. Mol Cell Proteomics. 2021 Jun 12;20:100096. doi: 10.1016/j.mcpro.2021.100096. Epub ahead of print. PMID: 34129941. https://pubmed.ncbi.nlm.nih.gov/34129941/

July 5, Pubcrawler Hits:

1. Balaton BP, Brown CJ. Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation. Epigenetics Chromatin. 2021 Jun 29;14(1):30. doi: 10.1186/s13072-021-00404-9. PMID: 34187555; PMCID: PMC8244145. https://pubmed.ncbi.nlm.nih.gov/34187555/

2. Skinnider MA, Scott NE, Prudova A, Kerr CH, Stoynov N, Stacey RG, Chan QWT, Rattray D, Gsponer J, Foster LJ. An atlas of protein-protein interactions across mouse tissues. Cell. 2021 Jun 22:S0092-8674(21)00704-2. doi: 10.1016/j.cell.2021.06.003. Epub ahead of print. PMID: 34214469. https://pubmed.ncbi.nlm.nih.gov/34214469/

June 28, Pubcrawler Hits:

1. Yong J, Johnson JD, Arvan P, Han J, Kaufman RJ. Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus. Nat Rev Endocrinol. 2021 Jun 23. doi: 10.1038/s41574-021-00510-4. Epub ahead of print. PMID: 34163039. https://pubmed.ncbi.nlm.nih.gov/34163039/

2. Satishkumar N, Alexander JAN, Poon R, Buggeln E, Argudín MA, Strynadka NCJ, Chatterjee SS. PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus. J Antimicrob Chemother. 2021 Jun 21:dkab201. doi: 10.1093/jac/dkab201. Epub ahead of print. PMID: 34151961. https://pubmed.ncbi.nlm.nih.gov/34151961/

June 21, Pubcrawler Hits:

1. Jun D, Zhang S, Grzędowski AJ, Mahey A, Beatty JT, Bizzotto D. Correlating structural assemblies of photosynthetic reaction centers on a gold electrode and the photocurrent - potential response. iScience. 2021 May 4;24(5):102500. doi: 10.1016/j.isci.2021.102500. PMID: 34113832; PMCID: PMC8170006. https://pubmed.ncbi.nlm.nih.gov/34113832/

2. Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV. Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles. Transfusion. 2021 Jun 14. doi: 10.1111/trf.16542. Epub ahead of print. PMID: 34121199. https://pubmed.ncbi.nlm.nih.gov/34121199/

3. Karahan G, Chan D, Shirane K, McClatchie T, Janssen S, Baltz JM, Lorincz M, Trasler J. Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations. Development. 2021 Jun 15:dev.199492. doi: 10.1242/dev.199492. Epub ahead of print. PMID: 34128976. https://pubmed.ncbi.nlm.nih.gov/34128976/

4. Rufenach B, Van Petegem F. Structure and function of STAC proteins: calcium channel modulators and critical components of muscle excitation-contraction coupling. J Biol Chem. 2021 Jun 12:100874. doi: 10.1016/j.jbc.2021.100874. Epub ahead of print. PMID: 34129875. https://pubmed.ncbi.nlm.nih.gov/34129875/

5. Rens C, Shapira T, Peña-Diaz S, Chao JD, Pfeifer T, Av-Gay Y. Apoptosis assessment in high-content and high-throughput screening assays. Biotechniques. 2021 Jun;70(6):309-318. doi: 10.2144/btn-2020-0164. Epub 2021 Jun 11. PMID: 34114488. https://pubmed.ncbi.nlm.nih.gov/34114488/

6. Onji M, Werschler N, Penninger J. A critical relationship between bone and fat: the role of bone marrow adipose-derived RANKL in bone metabolism. EMBO Rep. 2021 Jun 13:e52986. doi: 10.15252/embr.202152986. Epub ahead of print. PMID: 34121307. https://pubmed.ncbi.nlm.nih.gov/34121307/

June 14, Pubcrawler Hits:

1. Tam A, Leclair P, Li LV, Yang CX, Li X, Witzigmann D, Kulkarni JA, Hackett TL, Dorscheid DR, Singhera GK, Hogg JC, Cullis PR, Sin DD, Lim CJ. FAM13A as potential therapeutic target in modulating TGF-beta-induced airway tissue remodeling in COPD. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 9. doi: 10.1152/ajplung.00477.2020. Epub ahead of print. PMID: 34105356. https://pubmed.ncbi.nlm.nih.gov/34105356/

2. Kieft K, Zhou Z, Anderson RE, Buchan A, Campbell BJ, Hallam SJ, Hess M, Sullivan MB, Walsh DA, Roux S, Anantharaman K. Ecology of inorganic sulfur auxiliary metabolism in widespread bacteriophages. Nat Commun. 2021 Jun 9;12(1):3503. doi: 10.1038/s41467-021-23698-5. PMID: 34108477. https://pubmed.ncbi.nlm.nih.gov/34108477/

3. Abbasi U, Abbina S, Gill A, Takuechi LE, Kizhakkedathu JN. Role of Iron in the Molecular Pathogenesis of Diseases and Therapeutic Opportunities. ACS Chem Biol. 2021 Jun 9. doi: 10.1021/acschembio.1c00122. Epub ahead of print. PMID: 34102834. https://pubmed.ncbi.nlm.nih.gov/34102834/

4. Chen J, Debebe A, Zeng N, Kopp J, He L, Sander M, Stiles BL. Transformation of SOX9⁺ cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma. Sci Rep. 2021 Jun 3;11(1):11823. doi: 10.1038/s41598-021-90958-1. PMID: 34083580; PMCID: PMC8175600. https://pubmed.ncbi.nlm.nih.gov/34083580/

June 7, Pubcrawler Hits:

1. Inkster AM, Yuan V, Konwar C, Matthews AM, Brown CJ, Robinson WP. A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta. Biol Sex Differ. 2021 May 27;12(1):38. doi: 10.1186/s13293-021-00381-4. PMID: 34044884; PMCID: PMC8162041. https://pubmed.ncbi.nlm.nih.gov/34044884/

2. Kulkarni JA, Witzigmann D, Thomson SB, Chen S, Leavitt BR, Cullis PR, van der Meel R. The current landscape of nucleic acid therapeutics. Nat Nanotechnol. 2021 May 31. doi: 10.1038/s41565-021-00898-0. Epub ahead of print. PMID: 34059811. https://pubmed.ncbi.nlm.nih.gov/34059811/

3. Mouat IC, Morse ZJ, Shanina I, Brown KL, Horwitz MS. Latent gammaherpesvirus exacerbates arthritis through modification of age-associated B cells. Elife. 2021 Jun 3;10:e67024. doi: 10.7554/eLife.67024. Epub ahead of print. PMID: 34080972. https://pubmed.ncbi.nlm.nih.gov/34080972/

4. Wang S, Flibotte S, Camunas-Soler J, MacDonald PE, Johnson JD. A New Hypothesis for Type 1 Diabetes Risk: The At-Risk Allele at rs3842753 Associates With Increased Beta-cell INS Messenger RNA in a Meta-Analysis of Single-Cell RNA-Sequencing Data. Can J Diabetes. 2021 Apr 3:S1499-2671(21)00081-2. doi: 10.1016/j.jcjd.2021.03.007. Epub ahead of print. PMID: 34052132. https://pubmed.ncbi.nlm.nih.gov/34052132/

May 31, Pubcrawler Hits:

1. Roux S, Paul BG, Bagby SC, Nayfach S, Allen MA, Attwood G, Cavicchioli R, Chistoserdova L, Gruninger RJ, Hallam SJ, Hernandez ME, Hess M, Liu WT, McAllister TA, O'Malley MA, Peng X, Rich VI, Saleska SR, Eloe-Fadrosh EA. Ecology and molecular targets of hypermutation in the global microbiome. Nat Commun. 2021 May 24;12(1):3076. doi: 10.1038/s41467-021-23402-7. PMID: 34031405. https://pubmed.ncbi.nlm.nih.gov/34031405/

May 24, Pubcrawler Hits:

1. Muria A, Musso PY, Durrieu M, Portugal FR, Ronsin B, Gordon MD, Jeanson R, Isabel G. Social facilitation of long-lasting memory is mediated by CO₂ in Drosophila. Curr Biol. 2021 May 24;31(10):2065-2074.e5. doi: 10.1016/j.cub.2021.02.044. Epub 2021 Mar 18. PMID: 33740428. https://pubmed.ncbi.nlm.nih.gov/33740428/

2. Heda P, Alalola B, Almeida FR, Kim H, Peres BU, Pliska BT. Long-term periodontal changes associated with oral appliance treatment of obstructive sleep apnea. J Clin Sleep Med. 2021 May 14. doi: 10.5664/jcsm.9358. Epub ahead of print. PMID: 33985648. https://pubmed.ncbi.nlm.nih.gov/33985648/

3. Alcaraz LB, Mallavialle A, David T, Derocq D, Delolme F, Dieryckx C, Mollevi C, Boissière-Michot F, Simony-Lafontaine J, Du Manoir S, Huesgen PF, Overall CM, Tartare-Deckert S, Jacot W, Chardès T, Guiu S, Roger P, Reinheckel T, Moali C, Liaudet-Coopman E. A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment. Theranostics. 2021 Apr 15;11(13):6173-6192. doi: 10.7150/thno.58254. PMID: 33995652; PMCID: PMC8120228. https://pubmed.ncbi.nlm.nih.gov/33995652/

4. Jain N, Tamura K, Déjean G, Van Petegem F, Brumer H. Orthogonal Active-Site Labels for Mixed-Linkage endo-β-Glucanases. ACS Chem Biol. 2021 May 14. doi: 10.1021/acschembio.1c00063. Epub ahead of print. PMID: 33988963. https://pubmed.ncbi.nlm.nih.gov/33988963/

5. Brink KS, Henríquez JI, Grieco TM, Martin Del Campo JR, Fu K, Richman JM. Tooth Removal in the Leopard Gecko and the de novo Formation of Replacement Teeth. Front Physiol. 2021 May 4;12:576816. doi: 10.3389/fphys.2021.576816. PMID: 34012403; PMCID: PMC8126719. https://pubmed.ncbi.nlm.nih.gov/34012403/

6. Caveney NA, Workman SD, Yan R, Atkinson CE, Yu Z, Strynadka NCJ. CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution. Nat Commun. 2021 May 13;12(1):2775. doi: 10.1038/s41467-021-23063-6. PMID: 33986273; PMCID: PMC8119973. https://pubmed.ncbi.nlm.nih.gov/33986273/

7. Ajoolabady A, Aslkhodapasandhokmabad H, Libby P, Tuomilehto J, Lip GYH, Penninger JM, Richardson DR, Tang D, Zhou H, Wang S, Klionsky DJ, Kroemer G, Ren J. Ferritinophagy and ferroptosis in the management of metabolic diseases. Trends Endocrinol Metab. 2021 May 15:S1043-2760(21)00095-3. doi: 10.1016/j.tem.2021.04.010. Epub ahead of print. PMID: 34006412. https://pubmed.ncbi.nlm.nih.gov/34006412/

May 17, Pubcrawler Hits:

1. Siren EMJ, Luo HD, Bajaj S, MacKenzie J, Daneshi M, Martinez DM, Conway EM, Cheung KC, Kizhakkedathu JN. An improved in vitro model for studying the structural and functional properties of the endothelial glycocalyx in arteries, capillaries and veins. FASEB J. 2021 Jun;35(6):e21643. doi: 10.1096/fj.201802376RRRR. PMID: 33977574. https://pubmed.ncbi.nlm.nih.gov/33977574/

2. Devine DV. Rethinking platelet transfusion practices. Blood. 2021 May 13;137(19):2576-2577. doi: 10.1182/blood.2021011269. PMID: 33983425. https://pubmed.ncbi.nlm.nih.gov/33983425/

3. Vardaki MZ, Schulze HG, Serrano K, Blades MW, Devine DV, Turner RFB. Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy. Transfusion. 2021 May 10. doi: 10.1111/trf.16417. Epub ahead of print. PMID: 33969894. https://pubmed.ncbi.nlm.nih.gov/33969894/

4. Kuatsjah E, Chan ACK, Katahira R, Haugen SJ, Beckham GT, Murphy MEP, Eltis LD. Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6. J Biol Chem. 2021 May 6:100758. doi: 10.1016/j.jbc.2021.100758. Epub ahead of print. PMID: 33965373. https://pubmed.ncbi.nlm.nih.gov/33965373/

May 10, Pubcrawler Hits:

1. Bégin P, Callum J, Heddle NM, Cook R, Zeller MP, Tinmouth A, Fergusson DA, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitalle N, Bazin R, Shehata N, Finzi A, McGeer A, Scales DC, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Sachais BS, Loftsgard KC, Jamula E, Carruthers J, Duncan J, Lucier K, Li N, Liu Y, Armali C, Kron A, Modi D, Auclair MC, Cerro S, Avram M, Arnold DM. Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial. Trials. 2021 May 4;22(1):323. doi: 10.1186/s13063-021-05235-3. PMID: 33947446; PMCID: PMC8094980. https://pubmed.ncbi.nlm.nih.gov/33947446/

2. Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohoněk M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N. International Forum on Walking Blood Bank Programmes: Responses. Vox Sang. 2021 May 3. doi: 10.1111/vox.13102. Epub ahead of print. PMID: 33939177. https://pubmed.ncbi.nlm.nih.gov/33939177/

3. Rodriguez-Calvo T, Johnson JD, Overbergh L, Dunne JL. Neoepitopes in Type 1 Diabetes: Etiological Insights, Biomarkers and Therapeutic Targets. Front Immunol. 2021 Apr 19;12:667989. doi: 10.3389/fimmu.2021.667989. PMID: 33953728; PMCID: PMC8089389. https://pubmed.ncbi.nlm.nih.gov/33953728/

4. Skiba NP, Cady MA, Molday L, Han JYS, Lewis TR, Spencer WJ, Thompson WJ, Hiles S, Philp NJ, Molday RS, Arshavsky VY. TMEM67, TMEM237 and embigin in the complex with lactate transporter MCT1 are unique components of the photoreceptor outer segment plasma membrane. Mol Cell Proteomics. 2021 Apr 29:100088. doi: 10.1016/j.mcpro.2021.100088. Epub ahead of print. PMID: 33933680. https://pubmed.ncbi.nlm.nih.gov/33933680/

5. Hosseini-Farahabadi S, Baradaran-Heravi A, Zimmerman C, Choi K, Flibotte S, Roberge M. Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough. PLoS Biol. 2021 May 3;19(5):e3001221. doi: 10.1371/journal.pbio.3001221. Epub ahead of print. PMID: 33939688. https://pubmed.ncbi.nlm.nih.gov/33939688/

6. Av-Gay Y, Mori G, Pasca MR. Editorial: New Approaches Against Drug-Resistant M. tuberculosis. Front Microbiol. 2021 Apr 15;12:681420. doi: 10.3389/fmicb.2021.681420. PMID: 33936024; PMCID: PMC8081967. https://pubmed.ncbi.nlm.nih.gov/33936024/

May 3, Pubcrawler Hits:

1. Hadjesfandiari N, Khorshidfar M, Devine DV. Current Understanding of the Relationship between Blood Donor Variability and Blood Component Quality. Int J Mol Sci. 2021 Apr 11;22(8):3943. doi: 10.3390/ijms22083943. PMID: 33920459; PMCID: PMC8069744. https://pubmed.ncbi.nlm.nih.gov/33920459/

2. Bolger-Munro M, Choi K, Cheung F, Liu YT, Dang-Lawson M, Deretic N, Keane C, Gold MR. The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse. Front Cell Dev Biol. 2021 Apr 13;9:649433. doi: 10.3389/fcell.2021.649433. PMID: 33928084; PMCID: PMC8076898. https://pubmed.ncbi.nlm.nih.gov/33928084/

3. Lee W, Zernant J, Nagasaki T, Molday LL, Su PY, Fishman GA, Tsang SH, Molday RS, Allikmets R. Cis-acting modifiers in the ABCA4 locus contribute to the penetrance of the major disease-causing variant in Stargardt disease. Hum Mol Genet. 2021 Apr 28:ddab122. doi: 10.1093/hmg/ddab122. Epub ahead of print. PMID: 33909047. https://pubmed.ncbi.nlm.nih.gov/33909047/

4. Scala M, Efthymiou S, Sultan T, De Waele J, Panciroli M, Salpietro V, Maroofian R, Striano P, Van Petegem F, Houlden H, Bosmans F. Homozygous SCN1B variants causing early infantile epileptic encephalopathy 52 affect voltage-gated sodium channel function. Epilepsia. 2021 Apr 26. doi: 10.1111/epi.16913. Epub ahead of print. PMID: 33901312. https://pubmed.ncbi.nlm.nih.gov/33901312/

5. Muñoz-Muñoz L, Shoen C, Sweet G, Vitoria A, Bull TJ, Cynamon M, Thompson CJ, Ramón-García S. Repurposing Avermectins and Milbemycins against Mycobacteroides abscessus and Other Nontuberculous Mycobacteria. Antibiotics (Basel). 2021 Apr 3;10(4):381. doi: 10.3390/antibiotics10040381. PMID: 33916775; PMCID: PMC8066277. https://pubmed.ncbi.nlm.nih.gov/33916775/

6. Asanović I, Strandback E, Kroupova A, Pasajlic D, Meinhart A, Tsung-Pin P, Djokovic N, Anrather D, Schuetz T, Suskiewicz MJ, Sillamaa S, Köcher T, Beveridge R, Nikolic K, Schleiffer A, Jinek M, Hartl M, Clausen T, Penninger J, Macheroux P, Weitzer S, Martinez J. The oxidoreductase PYROXD1 uses NAD(P)⁺ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response. Mol Cell. 2021 Apr 23:S1097-2765(21)00312-9. doi: 10.1016/j.molcel.2021.04.007. Epub ahead of print. PMID: 33930333. https://pubmed.ncbi.nlm.nih.gov/33930333/

7. Cameron T, Bennet T, Rowe EM, Anwer M, Wellington CL, Cheung KC. Review of Design Considerations for Brain-on-a-Chip Models. Micromachines (Basel). 2021 Apr 15;12(4):441. doi: 10.3390/mi12040441. PMID: 33921018; PMCID: PMC8071412. https://pubmed.ncbi.nlm.nih.gov/33921018/

Apr 26, Pubcrawler Hits:

1. Chander N, Morstein J, Bolten JS, Shemet A, Cullis PR, Trauner D, Witzigmann D. Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release. Small. 2021 Apr 20:e2008198. doi: 10.1002/smll.202008198. Epub ahead of print. PMID: 33880882. https://pubmed.ncbi.nlm.nih.gov/33880882/

2. Chao JT, Roskelley CD, Loewen CJR. MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy. BMC Bioinformatics. 2021 Apr 20;22(1):202. doi: 10.1186/s12859-021-04117-4. PMID: 33879063; PMCID: PMC8056608. https://pubmed.ncbi.nlm.nih.gov/33879063/

3. Lu HY, Sharma M, Sharma AA, Lacson A, Szpurko A, Luider J, Dharmani-Khan P, Shameli A, Bell PA, Guilcher GMT, Lewis VA, Vasquez MR, Desai S, McGonigle L, Murguia-Favela L, Wright NAM, Sergi C, Wine E, Overall CM, Suresh S, Turvey SE. Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency. J Allergy Clin Immunol. 2021 Apr 16:S0091-6749(21)00612-6. doi: 10.1016/j.jaci.2021.04.006. Epub ahead of print. PMID: 33872653. https://pubmed.ncbi.nlm.nih.gov/33872653/

Apr 19, Pubcrawler Hits:

1. Friese A, Bauer K, Glombitza C, Ordoñez L, Ariztegui D, Heuer VB, Vuillemin A, Henny C, Nomosatryo S, Simister R, Wagner D, Bijaksana S, Vogel H, Melles M, Russell JM, Crowe SA, Kallmeyer J. Organic matter mineralization in modern and ancient ferruginous sediments. Nat Commun. 2021 Apr 13;12(1):2216. doi: 10.1038/s41467-021-22453-0. PMID: 33850127. https://pubmed.ncbi.nlm.nih.gov/33850127/

Apr 12, Pubcrawler Hits:

1. Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM. CD248 enhances tissue factor (TF) procoagulant function, promoting arterial and venous thrombosis in mouse models. J Thromb Haemost. 2021 Apr 8. doi: 10.1111/jth.15338. Epub ahead of print. PMID: 33830628. https://pubmed.ncbi.nlm.nih.gov/33830628/

2. Crowe SA, Simister RL, Spence JS, Kenward PA, Van Slyke AC, Lennox P, Carr N. Microbial community compositions in breast implant biofilms associated with contracted capsules. PLoS One. 2021 Apr 8;16(4):e0249261. doi: 10.1371/journal.pone.0249261. PMID: 33831065. https://pubmed.ncbi.nlm.nih.gov/33831065/

3. Wang X, Vlok M, Flibotte S, Jan E. Resurrection of a Viral Internal Ribosome Entry Site from a 700 Year Old Ancient Northwest Territories Cripavirus. Viruses. 2021 Mar 17;13(3):493. doi: 10.3390/v13030493. PMID: 33802878; PMCID: PMC8002689. https://pubmed.ncbi.nlm.nih.gov/33802878/

4. Balboa D, Iworima DG, Kieffer TJ. Human Pluripotent Stem Cells to Model Islet Defects in Diabetes. Front Endocrinol (Lausanne). 2021 Mar 22;12:642152. doi: 10.3389/fendo.2021.642152. PMID: 33828531; PMCID: PMC8020750. https://pubmed.ncbi.nlm.nih.gov/33828531/

5. Li FKK, Gale RT, Petrotchenko EV, Borchers CH, Brown ED, Strynadka NCJ. Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. J Struct Biol. 2021 Apr 2:107733. doi: 10.1016/j.jsb.2021.107733. Epub ahead of print. PMID: 33819634. https://pubmed.ncbi.nlm.nih.gov/33819634/

6. Rankine-Wilson LI, Shapira T, Sao Emani C, Av-Gay Y. From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis. Microbiology (Reading). 2021 Apr;167(4). doi: 10.1099/mic.0.001041. PMID: 33826491. https://pubmed.ncbi.nlm.nih.gov/33826491/

7. Ajoolabady A, Wang S, Kroemer G, Penninger JM, Uversky VN, Pratico D, Henninger N, Reiter RJ, Bruno A, Joshipura K, Aslkhodapasandhokmabad H, Klionsky DJ, Ren J. Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics. Pharmacol Ther. 2021 Apr 3:107848. doi: 10.1016/j.pharmthera.2021.107848. Epub ahead of print. PMID: 33823204. https://pubmed.ncbi.nlm.nih.gov/33823204/

Apr 5, Pubcrawler Hits:

1. Vogler J, Böttger R, Al Fayez N, Zhang W, Qin Z, Hohenwarter L, Chao PH, Rouhollahi E, Bilal N, Chen N, Lee B, Chen C, Wilkinson B, Kieffer TJ, Kulkarni JA, Cullis PR, Witzigmann D, Li SD. Altering the intra-liver distribution of phospholipid-free small unilamellar vesicles using temperature-dependent size-tunability. J Control Release. 2021 Mar 23;333:151-161. doi: 10.1016/j.jconrel.2021.03.025. Epub ahead of print. PMID: 33771624. https://pubmed.ncbi.nlm.nih.gov/33771624/

2. Zhao HW, Serrano K, Stefanoni D, D'Alessandro A, Devine DV. In Vitro Characterization and Metabolomic Analysis of Cold-Stored Platelets. J Proteome Res. 2021 Mar 29. doi: 10.1021/acs.jproteome.0c00792. Epub ahead of print. PMID: 33780259. https://pubmed.ncbi.nlm.nih.gov/33780259/

3. Zhang AMY, Wellberg EA, Kopp JL, Johnson JD. Hyperinsulinemia in Obesity, Inflammation, and Cancer. Diabetes Metab J. 2021 Mar 29. doi: 10.4093/dmj.2020.0250. Epub ahead of print. PMID: 33775061. https://pubmed.ncbi.nlm.nih.gov/33775061/

4. Fettig NM, Osborne LC. Direct and indirect effects of microbiota-derived metabolites on neuroinflammation in multiple sclerosis. Microbes Infect. 2021 Mar 25:104814. doi: 10.1016/j.micinf.2021.104814. Epub ahead of print. PMID: 33775860. https://pubmed.ncbi.nlm.nih.gov/33775860/

5. Millington JW, Brownrigg GP, Basner-Collins PJ, Sun Z, Rideout EJ. Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size. G3 (Bethesda). 2021 Jan 11:jkaa067. doi: 10.1093/g3journal/jkaa067. Epub ahead of print. PMID: 33793746. https://pubmed.ncbi.nlm.nih.gov/33793746/

6. Niu X, Rothe K, Chen M, Grasedieck S, Li R, Nam SE, Zhang X, Novakovskiy G, Ahn YH, Maksakova IA, Lai S, Zhang H, Yan J, Liu H, Zhao Y, Wu D, Ge Y, Wasserman W, Rouhi A, Kuchenbauer FC, Yip CK, Zhang Z, Jiang X. Targeting AXL Kinase Sensitizes Leukemic Stem and Progenitor Cells to Venetoclax Treatment in Acute Myeloid Leukemia. Blood. 2021 Mar 30:blood.2020007651. doi: 10.1182/blood.2020007651. Epub ahead of print. PMID: 33786587. https://pubmed.ncbi.nlm.nih.gov/33786587/

7. Nguyen J, Pepin D, Tropini C. Cause or effect? The spatial organization of pathogens and the gut microbiota in disease. Microbes Infect. 2021 Mar 25:104815. doi: 10.1016/j.micinf.2021.104815. Epub ahead of print. PMID: 33775859. https://pubmed.ncbi.nlm.nih.gov/33775859/

Mar 29, Pubcrawler Hits:

1. Shimell JJ, Globa A, Sepers MD, Wild AR, Matin N, Raymond LA, Bamji SX. Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyl transferase. J Cell Sci. 2021 Mar 23:jcs.254276. doi: 10.1242/jcs.254276. Epub ahead of print. PMID: 33758079. https://pubmed.ncbi.nlm.nih.gov/33758079/

2. Dixon-McDougall T, Brown CJ. Independent domains for recruitment of PRC1 and PRC2 by human XIST. PLoS Genet. 2021 Mar 22;17(3):e1009123. doi: 10.1371/journal.pgen.1009123. Epub ahead of print. PMID: 33750950. https://pubmed.ncbi.nlm.nih.gov/33750950/

3. Arbaeen AF, Schubert P, Sheffield WP, Devine DV. Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model. Transfusion. 2021 Mar 21. doi: 10.1111/trf.16382. Epub ahead of print. PMID: 33745131. https://pubmed.ncbi.nlm.nih.gov/33745131/

4. Notonier S, Werner AZ, Kuatsjah E, Dumalo L, Abraham PE, Hatmaker EA, Hoyt CB, Amore A, Ramirez KJ, Woodworth SP, Klingeman DM, Giannone RJ, Guss AM, Hettich RL, Eltis LD, Johnson CW, Beckham GT. Metabolism of syringyl lignin-derived compounds in Pseudomonas putida enables convergent production of 2-pyrone-4,6-dicarboxylic acid. Metab Eng. 2021 Mar 16;65:111-122. doi: 10.1016/j.ymben.2021.02.005. Epub ahead of print. PMID: 33741529. https://pubmed.ncbi.nlm.nih.gov/33741529/

5. Safabakhsh S, Panwar P, Barichello S, Sangha SS, Hanson PJ, Van Petegem F, Laksman Z. The Role of Phosphorylation in Atrial Fibrillation: A Focus on Mass Spectrometry Approaches. Cardiovasc Res. 2021 Mar 21:cvab095. doi: 10.1093/cvr/cvab095. Epub ahead of print. PMID: 33744917. https://pubmed.ncbi.nlm.nih.gov/33744917/

6. Danescu A, Rens EG, Rehki J, Woo J, Akazawa T, Fu K, Edelstein-Keshet L, Richman JM. Symmetry and fluctuation of cell movements in neural crest-derived facial mesenchyme. Development. 2021 Mar 23:dev.193755. doi: 10.1242/dev.193755. Epub ahead of print. PMID: 33757991. https://pubmed.ncbi.nlm.nih.gov/33757991/

7. Baradaran-Heravi A, Balgi AD, Hosseini-Farahabadi S, Choi K, Has C, Roberge M. Effect of small molecule eRF3 degraders on premature termination codon readthrough. Nucleic Acids Res. 2021 Mar 25:gkab194. doi: 10.1093/nar/gkab194. Epub ahead of print. PMID: 33764477. https://pubmed.ncbi.nlm.nih.gov/33764477/

8. Slaine PD, Kleer M, Duguay BA, Pringle ES, Kadijk E, Ying S, Balgi A, Roberge M, McCormick C, Khaperskyy DA. Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation. J Virol. 2021 Mar 24:JVI.00453-21. doi: 10.1128/JVI.00453-21. Epub ahead of print. PMID: 33762409. https://pubmed.ncbi.nlm.nih.gov/33762409/

9. Beskrovnaya P, Sexton DL, Golmohammadzadeh M, Hashimi A, Tocheva EI. Structural, Metabolic and Evolutionary Comparison of Bacterial Endospore and Exospore Formation. Front Microbiol. 2021 Mar 9;12:630573. doi: 10.3389/fmicb.2021.630573. PMID: 33767680; PMCID: PMC7985256. https://pubmed.ncbi.nlm.nih.gov/33767680/

Mar 22, Pubcrawler Hits:

1. Kuo CH, Huang YH, Chen PK, Lee GH, Tang MJ, Conway EM, Shi GY, Wu HL. VEGF-Induced Endothelial Podosomes via ROCK2-Dependent Thrombomodulin Expression Initiate Sprouting Angiogenesis. Arterioscler Thromb Vasc Biol. 2021 Mar 18:ATVBAHA121315931. doi: 10.1161/ATVBAHA.121.315931. Epub ahead of print. PMID: 33730876. https://pubmed.ncbi.nlm.nih.gov/33730876/

2. Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M. A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors. Transfusion. 2021 Mar 18. doi: 10.1111/trf.16364. Epub ahead of print. PMID: 33734448. https://pubmed.ncbi.nlm.nih.gov/33734448/

3. Sheng-Huei Lin C, Chan ACK, Vermeulen J, Brockerman J, Soni AS, Tanner ME, Gaynor EC, McIntosh LP, Simorre JP, Murphy MEP. Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni. J Biol Chem. 2021 Mar 9:100528. doi: 10.1016/j.jbc.2021.100528. Epub ahead of print. PMID: 33711341. https://pubmed.ncbi.nlm.nih.gov/33711341/

4. Ulloa O, Henríquez-Castillo C, Ramírez-Flandes S, Plominsky AM, Murillo AA, Morgan-Lang C, Hallam SJ, Stepanauskas R. The cyanobacterium Prochlorococcus has divergent light-harvesting antennae and may have evolved in a low-oxygen ocean. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2025638118. doi: 10.1073/pnas.2025638118. PMID: 33707213. https://pubmed.ncbi.nlm.nih.gov/33707213/

5. Demir F, Kizhakkedathu JN, Rinschen MM, Huesgen PF. MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets. Anal Chem. 2021 Mar 17. doi: 10.1021/acs.analchem.1c00310. Epub ahead of print. PMID: 33729755. https://pubmed.ncbi.nlm.nih.gov/33729755/

6. Abbasi U, Abbina S, Gill A, Bhagat V, Kizhakkedathu JN. A facile colorimetric method for the quantification of labile iron pool and total iron in cells and tissue specimens. Sci Rep. 2021 Mar 16;11(1):6008. doi: 10.1038/s41598-021-85387-z. PMID: 33727584; PMCID: PMC7971025. https://pubmed.ncbi.nlm.nih.gov/33727584/

7. Mulligan VK, Workman S, Sun T, Rettie S, Li X, Worrall LJ, Craven TW, King DT, Hosseinzadeh P, Watkins AM, Renfrew PD, Guffy S, Labonte JW, Moretti R, Bonneau R, Strynadka NCJ, Baker D. Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2012800118. doi: 10.1073/pnas.2012800118. PMID: 33723038. https://pubmed.ncbi.nlm.nih.gov/33723038/

Mar 15, Pubcrawler Hits:

1. Nam SE, Cheung YWS, Nguyen TN, Gong M, Chan S, Lazarou M, Yip CK. Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5. Commun Biol. 2021 Mar 5;4(1):291. doi: 10.1038/s42003-021-01830-x. PMID: 33674710. https://pubmed.ncbi.nlm.nih.gov/33674710/

Mar 8, Pubcrawler Hits:

1. Yip W, Hughes MR, Li Y, Cait A, Hirst M, Mohn WW, McNagny KM. Butyrate Shapes Immune Cell Fate and Function in Allergic Asthma. Front Immunol. 2021 Feb 15;12:628453. doi: 10.3389/fimmu.2021.628453. PMID: 33659009; PMCID: PMC7917140. https://pubmed.ncbi.nlm.nih.gov/33659009/

Mar 1, Pubcrawler Hits:

1. Klionsky DJ...Yip CK...(+ ~3000 others)...Tong C-K. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Feb 8:1-382. doi: 10.1080/15548627.2020.1797280. Epub ahead of print. PMID: 33634751. https://pubmed.ncbi.nlm.nih.gov/33634751/ 

2. Schubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV. Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation. Transfusion. 2021 Feb 24. doi: 10.1111/trf.16337. Epub ahead of print. PMID: 33629371. https://pubmed.ncbi.nlm.nih.gov/33629371/

3. Dill-McFarland KA, König SG, Mazel F, Oliver DC, McEwen LM, Hong KY, Hallam SJ. An integrated, modular approach to data science education in microbiology. PLoS Comput Biol. 2021 Feb 25;17(2):e1008661. doi: 10.1371/journal.pcbi.1008661. PMID: 33630850. https://pubmed.ncbi.nlm.nih.gov/33630850/

4. Rens C, Chao JD, Sexton DL, Tocheva EI, Av-Gay Y. Roles for phthiocerol dimycocerosate lipids in Mycobacterium tuberculosis pathogenesis. Microbiology (Reading). 2021 Feb 25. doi: 10.1099/mic.0.001042. Epub ahead of print. PMID: 33629944. https://pubmed.ncbi.nlm.nih.gov/33629944/

Feb 22, Pubcrawler Hits:

1. Balaton BP, Fornes O, Wasserman WW, Brown CJ. Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing. Epigenetics Chromatin. 2021 Feb 17;14(1):12. doi: 10.1186/s13072-021-00386-8. PMID: 33597016. https://pubmed.ncbi.nlm.nih.gov/33597016/

2. Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So-Osman C, Wood E, Devine DV, Spitalnik SL; ISBT COVID-19 Working Group. ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group. Vox Sang. 2021 Feb 12. doi: 10.1111/vox.13076. Epub ahead of print. PMID: 33578447. https://pubmed.ncbi.nlm.nih.gov/33578447/

3. Kumaran K, Krishnaveni GV, Suryanarayana KG, Prasad MP, Belavendra A, Atkinson S, Balasubramaniam R, Bandsma RHJ, Bhutta ZA, Chandak GR, Comelli EM, Davidge ST, Dennis CL, Hammond GL, Jha P, Joseph KS, Joshi SR, Krishna M, Lee K, Lye S, McGowan P, Nepomnaschy P, Padvetnaya V, Pyne S, Sachdev HS, Sahariah SA, Singhal N, Trasler J, Yajnik CS, Baird J, Barker M, Martin MC, Husain N, Sellen D, Fall CHD, Shah PS, Matthews SG. Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally-Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): a Healthy Life Trajectories Initiative (HeLTI) Study. BMJ Open. 2021 Feb 16;11(2):e045862. doi: 10.1136/bmjopen-2020-045862. PMID: 33593789. https://pubmed.ncbi.nlm.nih.gov/33593789/

4. Lismer A, Dumeaux V, Lafleur C, Lambrot R, Brind'Amour J, Lorincz MC, Kimmins S. Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring. Dev Cell. 2021 Feb 15:S1534-5807(21)00072-1. doi: 10.1016/j.devcel.2021.01.014. Epub ahead of print. PMID: 33596408. https://pubmed.ncbi.nlm.nih.gov/33596408/

5. Tamura K, Dejean G, Van Petegem F, Brumer H. Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota. J Biol Chem. 2021 Feb 12:100415. doi: 10.1016/j.jbc.2021.100415. Epub ahead of print. PMID: 33587952. https://pubmed.ncbi.nlm.nih.gov/33587952/

6. Maheux AF, Boudreau DK, Abed JY, Bérubé È, Brodeur S, Bernard KA, Hashimi A, Ducrey É, Guay ÉF, Raymond F, Corbeil J, Domingo MC, Roy PH, Boissinot M, Tocheva EI, Omar RF. Criibacterium bergeronii gen. nov., sp. nov., a new member of the family Peptostreptococcaceae, isolated from human clinical samples. Int J Syst Evol Microbiol. 2021 Feb 15. doi: 10.1099/ijsem.0.004691. Epub ahead of print. PMID: 33586648. https://pubmed.ncbi.nlm.nih.gov/33586648/

7. Turgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021 Feb 18. doi: 10.1038/s41388-021-01680-1. Epub ahead of print. PMID: 33603169. https://pubmed.ncbi.nlm.nih.gov/33603169/

Feb 15, Pubcrawler Hits:

1. Heidari E, Harrison AN, Jafarinia E, Tavasoli AR, Almadani N, Molday RS, Garshasbi M. Novel variants in critical domains of ATP8A2 and expansion of clinical spectrum. Hum Mutat. 2021 Feb 10. doi: 10.1002/humu.24180. Epub ahead of print. PMID: 33565221. https://pubmed.ncbi.nlm.nih.gov/33565221/

2. Mischkulnig M, Kiesel B, Lötsch D, Roetzer T, Borkovec M, Wadiura LI, Roessler K, Hervey-Jumper S, Penninger JM, Berger MS, Widhalm G, Erhart F. Heme Biosynthesis mRNA Expression Signature: Towards a Novel Prognostic Biomarker in Patients with Diffusely Infiltrating Gliomas. Cancers (Basel). 2021 Feb 7;13(4):662. doi: 10.3390/cancers13040662. PMID: 33562253. https://pubmed.ncbi.nlm.nih.gov/33562253/

Feb 8, Pubcrawler Hits:

1. Rayani K, Seffernick J, Li AY, Davis JP, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. Binding of calcium and magnesium to human cardiac Troponin C. J Biol Chem. 2021 Feb 3:100350. doi: 10.1016/j.jbc.2021.100350. Epub ahead of print. PMID: 33548225. https://pubmed.ncbi.nlm.nih.gov/33548225/

2. Woll KA, Haji-Ghassemi O, Van Petegem F. Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun. 2021 Feb 5;12(1):807. doi: 10.1038/s41467-021-21141-3. PMID: 33547325. https://pubmed.ncbi.nlm.nih.gov/33547325/

3. Holman PJ, Raineki C, Chao A, Grewal R, Haghighat S, Fung C, Morgan E, Ellis L, Yu W, Weinberg J. Altered social recognition memory and hypothalamic neuropeptide expression in adolescent male and female rats following prenatal alcohol exposure and/or early-life adversity. Psychoneuroendocrinology. 2021 Jan 21;126:105146. doi: 10.1016/j.psyneuen.2021.105146. Epub ahead of print. PMID: 33517167. https://pubmed.ncbi.nlm.nih.gov/33517167/

Feb 1, Pubcrawler Hits:

1. Lin H, Ascher DB, Myung Y, Lamborg CH, Hallam SJ, Gionfriddo CM, Holt KE, Moreau JW. Mercury methylation by metabolically versatile and cosmopolitan marine bacteria. ISME J. 2021 Jan 27. doi: 10.1038/s41396-020-00889-4. Epub ahead of print. PMID: 33504941. https://pubmed.ncbi.nlm.nih.gov/33504941/

2. Song X, Ji H, Li Y, Xiong Y, Qiu L, Zhong R, Tian M, Kizhakkedathu JN, Su B, Wei Q, Zhao W, Zhao C. Transient blood thinning during extracorporeal blood purification via the inactivation of coagulation factors by hydrogel microspheres. Nat Biomed Eng. 2021 Jan 25. doi: 10.1038/s41551-020-00673-x. Epub ahead of print. PMID: 33495638. https://pubmed.ncbi.nlm.nih.gov/33495638/

3. Mora M, Mell JC, Ehrlich GD, Ehrlich RL, Redfield RJ. Genome-wide analysis of DNA uptake across the outer membrane of naturally competent Haemophilus influenzae. iScience. 2020 Dec 30;24(1):102007. doi: 10.1016/j.isci.2020.102007. PMID: 33490915; PMCID: PMC7811141. https://pubmed.ncbi.nlm.nih.gov/33490915/

Jan 25, Pubcrawler Hits:

1. Shpilka T, Du Y, Yang Q, Melber A, Uma Naresh N, Lavelle J, Kim S, Liu P, Weidberg H, Li R, Yu J, Zhu LJ, Strittmatter L, Haynes CM. UPR^mt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans. Nat Commun. 2021 Jan 20;12(1):479. doi: 10.1038/s41467-020-20784-y. PMID: 33473112. https://pubmed.ncbi.nlm.nih.gov/33473112/

Jan 18, Pubcrawler Hits:

1. Terada T, Kulkarni JA, Huynh A, Chen S, van der Meel R, Tam YYC, Cullis PR. Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach. Langmuir. 2021 Jan 13. doi: 10.1021/acs.langmuir.0c03039. Epub ahead of print. PMID: 33439022. https://pubmed.ncbi.nlm.nih.gov/33439022/

2. Martin BJE, Brind'Amour J, Kuzmin A, Jensen KN, Liu ZC, Lorincz M, Howe LJ. Transcription shapes genome-wide histone acetylation patterns. Nat Commun. 2021 Jan 11;12(1):210. doi: 10.1038/s41467-020-20543-z. PMID: 33431884. https://pubmed.ncbi.nlm.nih.gov/33431884/

3. Mohamud Y, Xue YC, Liu H, Ng CS, Bahreyni A, Jan E, Luo H. The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy. Biochem Biophys Res Commun. 2021 Jan 8;540:75-82. doi: 10.1016/j.bbrc.2020.12.091. Epub ahead of print. PMID: 33450483. https://pubmed.ncbi.nlm.nih.gov/33450483/

4. Gerak CAN, Cho SY, Kolesnikov M, Okon M, Murphy MEP, Sessions RB, Roberge M, McIntosh LP. Biophysical characterization of the ETV6 PNT domain polymerization interfaces. J Biol Chem. 2021 Jan 12:100284. doi: 10.1016/j.jbc.2021.100284. Epub ahead of print. PMID: 33450226. https://pubmed.ncbi.nlm.nih.gov/33450226/

5. Amenyogbe N, Dimitriu P, Smolen KK, Brown EM, Shannon CP, Tebbutt SJ, Cooper PJ, Marchant A, Goetghebuer T, Esser M, Finlay BB, Kollmann TR, Mohn WW. Biogeography of the Relationship between the Child Gut Microbiome and Innate Immune System. mBio. 2021 Jan 12;12(1):e03079-20. doi: 10.1128/mBio.03079-20. PMID: 33436437. https://pubmed.ncbi.nlm.nih.gov/33436437/

6. Millington JW, Brownrigg GP, Chao C, Sun Z, Basner-Collins PJ, Wat LW, Hudry B, Miguel-Aliaga I, Rideout EJ. Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity. Elife. 2021 Jan 15;10:e58341. doi: 10.7554/eLife.58341. Epub ahead of print. PMID: 33448263. https://pubmed.ncbi.nlm.nih.gov/33448263/

Jan 11, Pubcrawler Hits:

1. Terada T, Kulkarni JA, Huynh A, Tam YYC, Cullis P. Protective Effect of Edaravone against Cationic Lipid-Mediated Oxidative Stress and Apoptosis. Biol Pharm Bull. 2021;44(1):144-149. doi: 10.1248/bpb.b20-00679. PMID: 33390543. https://pubmed.ncbi.nlm.nih.gov/33390543/

2. Perez-Borrajero C, Heinkel F, Gsponer J, McIntosh LP. Conformational Plasticity and DNA-Binding Specificity of the Eukaryotic Transcription Factor Pax5. Biochemistry. 2021 Jan 5. doi: 10.1021/acs.biochem.0c00737. Epub ahead of print. PMID: 33398994. https://pubmed.ncbi.nlm.nih.gov/33398994/

3. Mesnil M, Defamie N, Naus C, Sarrouilhe D. Brain Disorders and Chemical Pollutants: A Gap Junction Link? Biomolecules. 2020 Dec 31;11(1):E51. doi: 10.3390/biom11010051. PMID: 33396565. https://pubmed.ncbi.nlm.nih.gov/33396565/

4. Hepburn M, Saltzberg DJ, Lee L, Fang S, Atkinson C, Strynadka NCJ, Sali A, Lees-Miller SP, Schriemer DC. The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex. Structure. 2020 Dec 30:S0969-2126(20)30473-1. doi: 10.1016/j.str.2020.12.006. Epub ahead of print. PMID: 33412091. https://pubmed.ncbi.nlm.nih.gov/33412091/

5. Moulson AJ, Av-Gay Y. BCG immunomodulation: From the 'hygiene hypothesis' to COVID-19. Immunobiology. 2020 Dec 24;226(1):152052. doi: 10.1016/j.imbio.2020.152052. Epub ahead of print. PMID: 33418320. https://pubmed.ncbi.nlm.nih.gov/33418320/

Jan 4, Pubcrawler Hits:

1. Noonan AJC, Qiu Y, Ho JCH, Ocampo J, Vreugdenhil KA, Marr RA, Zhao Z, Yoshikuni Y, Hallam SJ. CRAGE-mediated insertion of fluorescent chromosomal markers for accurate and scalable measurement of co-culture dynamics in Escherichia coli. Synth Biol (Oxf). 2020 Sep 3;5(1):ysaa015. doi: 10.1093/synbio/ysaa015. PMID: 33381654; PMCID: PMC7751189. https://pubmed.ncbi.nlm.nih.gov/33381654/

2. Garces FA, Scortecci JF, Molday RS. Functional Characterization of ABCA4 Missense Variants Linked to Stargardt Macular Degeneration. Int J Mol Sci. 2020 Dec 27;22(1):E185. doi: 10.3390/ijms22010185. PMID: 33375396. https://pubmed.ncbi.nlm.nih.gov/33375396/

3. Tam V, Chen P, Yee A, Solis N, Klein T, Kudelko M, Sharma R, Chan WC, Overall CM, Haglund L, Sham PC, Cheah KSE, Chan D. DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics. Elife. 2020 Dec 31;9:e64940. doi: 10.7554/eLife.64940. Epub ahead of print. PMID: 33382035. https://pubmed.ncbi.nlm.nih.gov/33382035/

4. McLean MA, Niknafs N, Scoten OC, Chau CMY, MacKay M, Weinberg J, Synnes A, Miller SP, Grunau RE. Sensory processing and cortisol at age 4 years: Procedural pain-related stress in children born very preterm. Dev Psychobiol. 2020 Dec 29. doi: 10.1002/dev.22079. Epub ahead of print. PMID: 33377181. https://pubmed.ncbi.nlm.nih.gov/33377181/

5. Beskrovnaya P, Fakih D, Morneau I, Hashimi A, Bello DG, Xing S, Nanci A, Huan T, Tocheva EI. No endospore formation confirmed in members of the phylum Proteobacteria. Appl Environ Microbiol. 2020 Dec 18:AEM.02312-20. doi: 10.1128/AEM.02312-20. Epub ahead of print. PMID: 33355101. https://pubmed.ncbi.nlm.nih.gov/33355101/

6. Paolino M, Koglgruber R, Cronin SJF, Uribesalgo I, Rauscher E, Harreiter J, Schuster M, Bancher-Todesca D, Pranjic B, Novatchkova M, Fededa JP, White AJ, Sigl V, Dekan S, Penz T, Bock C, Kenner L, Holländer GA, Anderson G, Kautzky-Willer A, Penninger JM. RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy. Nature. 2020 Dec 23. doi: 10.1038/s41586-020-03071-0. Epub ahead of print. PMID: 33361811. https://pubmed.ncbi.nlm.nih.gov/33361811/

Dec 28, Pubcrawler Hits:

1. Gerak CAN, Zhang SM, Balgi AD, Sadowski IJ, Sessions RB, McIntosh LP, Roberge M. A Multipronged Screening Approach Targeting Inhibition of ETV6 PNT Domain Polymerization. SLAS Discov. 2020 Dec 21:2472555220979599. doi: 10.1177/2472555220979599. Epub ahead of print. PMID: 33345679. https://pubmed.ncbi.nlm.nih.gov/33345679/

2. Hillebrand GG, Dimitriu P, Malik K, Park Y, Qu D, Mohn WW, Kong R. Temporal Variation of the Facial Skin Microbiome: A 2-Year Longitudinal Study in Healthy Adults. Plast Reconstr Surg. 2021 Jan 1;147(1S-2):50S-61S. doi: 10.1097/PRS.0000000000007621. PMID: 33347075. https://pubmed.ncbi.nlm.nih.gov/33347075/

Dec 21, Pubcrawler Hits:

1. M A Basher AR, Hallam SJ. Leveraging heterogeneous network embedding for metabolic pathway prediction. Bioinformatics. 2020 Oct 20:btaa906. doi: 10.1093/bioinformatics/btaa906. Epub ahead of print. PMID: 33305310. https://pubmed.ncbi.nlm.nih.gov/33305310/

2. Márquez AC, Shanina I, Horwitz MS. Multiple Sclerosis-Like Symptoms in Mice Are Driven by Latent γHerpesvirus-68 Infected B Cells. Front Immunol. 2020 Nov 19;11:584297. doi: 10.3389/fimmu.2020.584297. PMID: 33329556; PMCID: PMC7711133. https://pubmed.ncbi.nlm.nih.gov/33329556/

3. Shannon CP, Blimkie TM, Ben-Othman R, Gladish N, Amenyogbe N, Drissler S, Edgar RD, Chan Q, Krajden M, Foster LJ, Kobor MS, Mohn WW, Brinkman RR, Le Cao KA, Scheuermann RH, Tebbutt SJ, Hancock REW, Koff WC, Kollmann TR, Sadarangani M, Lee AH. Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort. Front Immunol. 2020 Nov 30;11:578801. doi: 10.3389/fimmu.2020.578801. PMID: 33329547; PMCID: PMC7734088. https://pubmed.ncbi.nlm.nih.gov/33329547/

4. Gómez-Aleza C, Nguyen B, Yoldi G, Ciscar M, Barranco A, Hernández-Jiménez E, Maetens M, Salgado R, Zafeiroglou M, Pellegrini P, Venet D, Garaud S, Trinidad EM, Benítez S, Vuylsteke P, Polastro L, Wildiers H, Simon P, Lindeman G, Larsimont D, Van den Eynden G, Velghe C, Rothé F, Willard-Gallo K, Michiels S, Muñoz P, Walzer T, Planelles L, Penninger J, Azim HA Jr, Loi S, Piccart M, Sotiriou C, González-Suárez E. Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells. Nat Commun. 2020 Dec 10;11(1):6335. doi: 10.1038/s41467-020-20138-8. PMID: 33303745; PMCID: PMC7728758. https://pubmed.ncbi.nlm.nih.gov/33303745/

Dec 14, Pubcrawler Hits:

1. Farrera-Calderon RG, Pallegar P, Westbye AB, Wiesmann C, Lang AS, Beatty JT. The CckA-ChpT-CtrA phosphorelay controlling Rhodobacter capsulatus gene transfer agent (RcGTA) production is bi-directional and regulated by cyclic-di-GMP. J Bacteriol. 2020 Dec 7:JB.00525-20. doi: 10.1128/JB.00525-20. Epub ahead of print. PMID: 33288624. https://pubmed.ncbi.nlm.nih.gov/33288624/

2. Chazeirat T, Denamur S, Bojarski KK, Andrault PM, Sizaret D, Zhang F, Saidi A, Tardieu M, Linhardt RJ, Labarthe F, Brömme D, Samsonov SA, Lalmanach G, Lecaille F. The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V. Carbohydr Polym. 2021 Feb 1;253:117261. doi: 10.1016/j.carbpol.2020.117261. Epub 2020 Oct 20. PMID: 33278943. https://pubmed.ncbi.nlm.nih.gov/33278943/

3. Salmikangas S, Laiho JE, Kalander K, Laajala M, Honkimaa A, Shanina I, Oikarinen S, Horwitz MS, Hyöty H, Marjomäki V. Detection of Viral -RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues. Microorganisms. 2020 Dec 4;8(12):E1928. doi: 10.3390/microorganisms8121928. PMID: 33291747. https://pubmed.ncbi.nlm.nih.gov/33291747/

4. Overall CM. The Human Proteome: 90% in the Light, 10% on the Dark Side. J Proteome Res. 2020 Dec 4;19(12):4731-4734. doi: 10.1021/acs.jproteome.0c00914. PMID: 33272019. https://pubmed.ncbi.nlm.nih.gov/33272019/

5. Jenkins ML, Harris NJ, Dalwadi U, Fleming KD, Ziemianowicz DS, Rafiei A, Martin EM, Schriemer DC, Yip CK, Burke JE. The substrate specificity of the human TRAPPII complex's Rab-guanine nucleotide exchange factor activity. Commun Biol. 2020 Dec 4;3(1):735. doi: 10.1038/s42003-020-01459-2. PMID: 33277614; PMCID: PMC7719173. https://pubmed.ncbi.nlm.nih.gov/33277614/

6. Tsukasaki M, Huynh NC, Okamoto K, Muro R, Terashima A, Kurikawa Y, Komatsu N, Pluemsakunthai W, Nitta T, Abe T, Kiyonari H, Okamura T, Sakai M, Matsukawa T, Matsumoto M, Kobayashi Y, Penninger JM, Takayanagi H. Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution. Nat Metab. 2020 Dec 7. doi: 10.1038/s42255-020-00318-y. Epub ahead of print. PMID: 33288951. https://pubmed.ncbi.nlm.nih.gov/33288951/

Dec 7, Pubcrawler Hits:

1. Long RKM, Moriarty KP, Cardoen B, Gao G, Vogl AW, Jean F, Hamarneh G, Nabi IR. Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum. Sci Rep. 2020 Dec 1;10(1):20937. doi: 10.1038/s41598-020-77170-3. PMID: 33262363; PMCID: PMC7708840. https://pubmed.ncbi.nlm.nih.gov/33262363/

2. Ben-Othman R, Cai B, Liu AC, Varankovich N, He D, Blimkie TM, Lee AH, Gill EE, Novotny M, Aevermann B, Drissler S, Shannon CP, McCann S, Marty K, Bjornson G, Edgar RD, Lin DTS, Gladish N, Maclsaac J, Amenyogbe N, Chan Q, Llibre A, Collin J, Landais E, Le K, Reiss SM, Koff WC, Havenar-Daughton C, Heran M, Sangha B, Walt D, Krajden M, Crotty S, Sok D, Briney B, Burton DR, Duffy D, Foster LJ, Mohn WW, Kobor MS, Tebbutt SJ, Brinkman RR, Scheuermann RH, Hancock REW, Kollmann TR, Sadarangani M. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. Front Immunol. 2020 Nov 4;11:580373. doi: 10.3389/fimmu.2020.580373. PMID: 33250895; PMCID: PMC7672042. https://pubmed.ncbi.nlm.nih.gov/33250895/

3. Yang H, Mirsepasi-Lauridsen HC, Struve C, Allaire JM, Sivignon A, Vogl W, Bosman ES, Ma C, Fotovati A, Reid GS, Li X, Petersen AM, Gouin SG, Barnich N, Jacobson K, Yu HB, Krogfelt KA, Vallance BA. Ulcerative Colitis-associated E. coli pathobionts potentiate colitis in susceptible hosts. Gut Microbes. 2020 Dec 1:1-19. doi: 10.1080/19490976.2020.1847976. Epub ahead of print. PMID: 33258388. https://pubmed.ncbi.nlm.nih.gov/33258388/

Nov 30, Pubcrawler Hits:

1. Kulkarni JA, Thomson SB, Zaifman J, Leung J, Wagner PK, Hill A, Tam YYC, Cullis PR, Petkau TL, Leavitt BR. Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles. Nanoscale. 2020 Nov 26. doi: 10.1039/d0nr06816k. Epub ahead of print. PMID: 33241838. https://pubmed.ncbi.nlm.nih.gov/33241838/

2. Schulze HG, Rangan S, Vardaki M, Iworima D, Kieffer T, Blades M, Turner R, Piret JM. EXPRESS: Augmented Two-Dimensional Correlation Spectroscopy for the Joint Analysis of Correlated Changes in Spectroscopic and Disparate Sources. Appl Spectrosc. 2020 Nov 24:3702820979331. doi: 10.1177/0003702820979331. Epub ahead of print. PMID: 33231477. https://pubmed.ncbi.nlm.nih.gov/33231477/

3. Canals Hernaez D, Hughes MR, Dean P, Bergqvist P, Samudio I, Blixt O, Wiedemeyer K, Li Y, Bond C, Cruz E, Köbel M, Gilks B, Roskelley CD, McNagny KM. PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin. J Immunother Cancer. 2020 Nov;8(2):e001128. doi: 10.1136/jitc-2020-001128. PMID: 33243933. https://pubmed.ncbi.nlm.nih.gov/33243933/

4. Sullivan KE, Kendrick RM, Cembrowski MS. Elucidating memory in the brain via single-cell transcriptomics. J Neurochem. 2020 Nov 23. doi: 10.1111/jnc.15250. Epub ahead of print. PMID: 33230878. https://pubmed.ncbi.nlm.nih.gov/33230878/

Nov 23, Pubcrawler Hits:

1. Gazitúa MC, Vik DR, Roux S, Gregory AC, Bolduc B, Widner B, Mulholland MR, Hallam SJ, Ulloa O, Sullivan MB. Potential virus-mediated nitrogen cycling in oxygen-depleted oceanic waters. ISME J. 2020 Nov 16. doi: 10.1038/s41396-020-00825-6. Epub ahead of print. PMID: 33199808. https://pubmed.ncbi.nlm.nih.gov/33199808/

2. Kubiura-Ichimaru M, Ito T, Lefebvre L, Tada M. Cyclic DNA remethylation following active demethylation at euchromatic regions in mouse embryonic stem cells. Chromosome Res. 2020 Nov 17. doi: 10.1007/s10577-020-09645-y. Epub ahead of print. PMID: 33205231. https://pubmed.ncbi.nlm.nih.gov/33205231/

3. Khater IM, Nabi IR, Hamarneh G. A Review of Super-Resolution Single-Molecule Localization Microscopy Cluster Analysis and Quantification Methods. Patterns (N Y). 2020 Jun 12;1(3):100038. doi: 10.1016/j.patter.2020.100038. PMID: 33205106; PMCID: PMC7660399. https://pubmed.ncbi.nlm.nih.gov/33205106/

4. Attwood KM, Robichaud A, Westhaver LP, Castle EL, Brandman DM, Balgi AD, Roberge M, Colp P, Croul S, Kim I, McCormick C, Corcoran JA, Weeks A. Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells. Cell Death Dis. 2020 Nov 17;11(11):989. doi: 10.1038/s41419-020-03159-5. PMID: 33203845; PMCID: PMC7673037. https://pubmed.ncbi.nlm.nih.gov/33203845/

5. Lee J, Worrall LJ, Vuckovic M, Rosell FI, Gentile F, Ton AT, Caveney NA, Ban F, Cherkasov A, Paetzel M, Strynadka NCJ. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun. 2020 Nov 18;11(1):5877. doi: 10.1038/s41467-020-19662-4. PMID: 33208735. https://pubmed.ncbi.nlm.nih.gov/33208735/

6. Fennell LM, Gomez Diaz C, Deszcz L, Kavirayani A, Hoffmann D, Yanagitani K, Schleiffer A, Mechtler K, Hagelkruys A, Penninger J, Ikeda F. Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. EMBO J. 2020 Nov 20:e103303. doi: 10.15252/embj.2019103303. Epub ahead of print. PMID: 33215740. https://pubmed.ncbi.nlm.nih.gov/33215740/

7. Stebbing J, Sánchez Nievas G, Falcone M, Youhanna S, Richardson P, Ottaviani S, Shen JX, Sommerauer C, Tiseo G, Ghiadoni L, Virdis A, Monzani F, Rizos LR, Forfori F, Avendaño-Céspedes A, De Marco S, Carrozzi L, Lena F, Sánchez-Jurado PM, Lacerenza LG, Cesira N, Caldevilla-Bernardo D, Perrella A, Niccoli L, Méndez LS, Matarrese D, Goletti D, Tan YJ, Monteil V, Dranitsaris G, Cantini F, Farcomeni A, Dutta S, Burley SK, Zhang H, Pistello M, Li W, Mas Romero M, Andrés Pretel F, Simón-Talero RS, García-Molina R, Kutter C, Felce JH, Nizami ZF, Miklosi AG, Penninger JM, Menichetti F, Mirazimi A, Abizanda P, Lauschke VM. JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality. Sci Adv. 2020 Nov 13:eabe4724. doi: 10.1126/sciadv.abe4724. Epub ahead of print. PMID: 33187978. https://pubmed.ncbi.nlm.nih.gov/33187978/

8. Choi JR, Lee JH, Xu A, Matthews K, Xie S, Duffy SP, Ma H. Monolithic hydrogel nanowells-in-microwells enabling simultaneous single cell secretion and phenotype analysis. Lab Chip. 2020 Nov 17. doi: 10.1039/d0lc00965b. Epub ahead of print. PMID: 33201962. https://pubmed.ncbi.nlm.nih.gov/33201962/

9. Berryman S, Matthews K, Lee JH, Duffy SP, Ma H. Image-based phenotyping of disaggregated cells using deep learning. Commun Biol. 2020 Nov 13;3(1):674. doi: 10.1038/s42003-020-01399-x. PMID: 33188302; PMCID: PMC7666170. https://pubmed.ncbi.nlm.nih.gov/33188302/

Nov 16, Pubcrawler Hits:

1. Gammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R. Buffy coat platelets coming to America: Are we ready? Transfusion. 2020 Nov 10. doi: 10.1111/trf.16184. Epub ahead of print. PMID: 33174258. https://pubmed.ncbi.nlm.nih.gov/33174258/

2. Shim YA, Weliwitigoda A, Campbell T, Dosanjh M, Johnson P. Splenic erythroid progenitors decrease TNFα production by macrophages and reduce systemic inflammation in a mouse model of T cell-induced colitis. Eur J Immunol. 2020 Nov 12. doi: 10.1002/eji.202048687. Epub ahead of print. PMID: 33180325. https://pubmed.ncbi.nlm.nih.gov/33180325/

3. Majewski DD, Lyons BJE, Atkinson CE, Strynadka NCJ. Cryo-EM analysis of the SctV cytosolic domain from the enteropathogenic E. coli T3SS injectisome. J Struct Biol. 2020 Oct 28;212(3):107660. doi: 10.1016/j.jsb.2020.107660. Epub ahead of print. PMID: 33129970. https://pubmed.ncbi.nlm.nih.gov/33129970/

4. Monteil V, Dyczynski M, Lauschke VM, Kwon H, Wirnsberger G, Youhanna S, Zhang H, S Slutsky A, Hurtado Del Pozo C, Horn M, Montserrat N, Penninger JM, Mirazimi A. Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection. EMBO Mol Med. 2020 Nov 12:e13426. doi: 10.15252/emmm.202013426. Epub ahead of print. PMID: 33179852. https://pubmed.ncbi.nlm.nih.gov/33179852/

5. Penninger JM, Grant MB, Sung JJY. The Role of Angiotensin Converting Enzyme 2 (ACE2) in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection. Gastroenterology. 2020 Oct 29:S0016-5085(20)35327-0. doi: 10.1053/j.gastro.2020.07.067. Epub ahead of print. PMID: 33130103. https://pubmed.ncbi.nlm.nih.gov/33130103/

Nov 9, Pubcrawler Hits:

1. Berndt AJ, Othonos KM, Lian T, Flibotte S, Miao M, Buiyan S, Cho RY, Fong JS, Hur SA, Pavlidis P, Allan DW. A low affinity cis-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons. Elife. 2020 Oct 30;9:e59650. doi: 10.7554/eLife.59650. Epub ahead of print. PMID: 33124981. https://pubmed.ncbi.nlm.nih.gov/33124981/

2. Vesnaver E, Goldman M, O'Brien S, MacPherson P, Butler-Foster T, Lapierre D, Otis J, Devine DV, Germain M, Rosser A, MacDonagh R, Randall T, Osbourne-Sorrell W, Clement-Thorne B, Al-Bakri TB, Rubini KA, Hill NE, Presseau J. Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study. Health Res Policy Syst. 2020 Nov 2;18(1):131. doi: 10.1186/s12961-020-00643-4. PMID: 33138828; PMCID: PMC7605323. https://pubmed.ncbi.nlm.nih.gov/33138828/

3. Levy-Booth DJ, Hashimi A, Roccor R, Liu LY, Renneckar S, Eltis LD, Mohn WW. Genomics and metatranscriptomics of biogeochemical cycling and degradation of lignin-derived aromatic compounds in thermal swamp sediment. ISME J. 2020 Nov 2. doi: 10.1038/s41396-020-00820-x. Epub ahead of print. PMID: 33139871. https://pubmed.ncbi.nlm.nih.gov/33139871/

4. Irwin NAT, Pittis AA, Mathur V, Howe LJ, Keeling PJ, Lynn DH, Bourland WA. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Curr Biol. 2020 Oct 27:S0960-9822(20)31447-0. doi: 10.1016/j.cub.2020.09.077. Epub ahead of print. PMID: 33125869. https://pubmed.ncbi.nlm.nih.gov/33125869/

5. Pereira S, Cline DL, Glavas MM, Covey SD, Kieffer TJ. Tissue-specific effects of leptin on glucose and lipid metabolism. Endocr Rev. 2020 Nov 5:bnaa027. doi: 10.1210/endrev/bnaa027. Epub ahead of print. PMID: 33150398. https://pubmed.ncbi.nlm.nih.gov/33150398/

6. Wallert M, Nie C, Anilkumar P, Abbina S, Bhatia S, Ludwig K, Kizhakkedathu JN, Haag R, Block S. Mucin-Inspired, High Molecular Weight Virus Binding Inhibitors Show Biphasic Binding Behavior to Influenza A Viruses. Small. 2020 Nov 1:e2004635. doi: 10.1002/smll.202004635. Epub ahead of print. PMID: 33135314. https://pubmed.ncbi.nlm.nih.gov/33135314/

7. Millington JW, Rideout EJ. Sexual Dimorphism: Ecdysone Modulates Sex Differences in the Gut. Curr Biol. 2020 Nov 2;30(21):R1327-R1330. doi: 10.1016/j.cub.2020.08.088. PMID: 33142105. https://pubmed.ncbi.nlm.nih.gov/33142105/

8. Pazos M, Peters K, Boes A, Safaei Y, Kenward C, Caveney NA, Laguri C, Breukink E, Strynadka NCJ, Simorre JP, Terrak M, Vollmer W. SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. mBio. 2020 Nov 3;11(6):e02796-20. doi: 10.1128/mBio.02796-20. PMID: 33144379. https://pubmed.ncbi.nlm.nih.gov/33144379/

9. Cheung YWS, Nam SE, Yip CK. Recent Advances in Single-Particle Electron Microscopic Analysis of Autophagy Degradation Machinery. Int J Mol Sci. 2020 Oct 28;21(21):E8051. doi: 10.3390/ijms21218051. PMID: 33126766. https://pubmed.ncbi.nlm.nih.gov/33126766/

10. Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM. Human recombinant soluble ACE2 in severe COVID-19. Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24. Erratum in: Lancet Respir Med. 2020 Nov;8(11):e78. PMID: 33131609; PMCID: PMC7515587. https://pubmed.ncbi.nlm.nih.gov/33131609/

Nov 2, Pubcrawler Hits:

1. Toews JN, Hammond GL, Viau V. Liver at the nexus of rat postnatal HPA axis maturation and sexual dimorphism. J Endocrinol. 2020 Oct 1:JOE-20-0286.R1. doi: 10.1530/JOE-20-0286. Epub ahead of print. PMID: 33112814. https://pubmed.ncbi.nlm.nih.gov/33112814/

2. Cloherty APM, Olmstead AD, Ribeiro CMS, Jean F. Hijacking of Lipid Droplets by Hepatitis C, Dengue and Zika Viruses-From Viral Protein Moonlighting to Extracellular Release. Int J Mol Sci. 2020 Oct 24;21(21):E7901. doi: 10.3390/ijms21217901. PMID: 33114346. https://pubmed.ncbi.nlm.nih.gov/33114346/

3. Li S, Huang Z, Li X, Zhao Y, Jiang X, Wen Y, Luo H, Wang L, Guan Q, Cafeeva I, Brooks DE, Nguan CYC, Kizhakkedathu JN, Du C. Evaluation of hyperbranched polyglycerol for cold perfusion and storage of donor kidneys in a pig model of kidney autotransplantation. J Biomed Mater Res B Appl Biomater. 2020 Oct 24:e34750. doi: 10.1002/jbm.b.34750. Epub ahead of print. PMID: 33098184. https://pubmed.ncbi.nlm.nih.gov/33098184/

4. Richard Albert J, Au Yeung WK, Toriyama K, Kobayashi H, Hirasawa R, Brind'Amour J, Bogutz A, Sasaki H, Lorincz M. Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo. Nat Commun. 2020 Oct 27;11(1):5417. doi: 10.1038/s41467-020-19279-7. PMID: 33110091. https://pubmed.ncbi.nlm.nih.gov/33110091/

5. Price RM, Budzynski MA, Kundra S, Teves SS. Advances in visualizing transcription factor-DNA interactions. Genome. 2020 Oct 28. doi: 10.1139/gen-2020-0086. Epub ahead of print. PMID: 33113335. https://pubmed.ncbi.nlm.nih.gov/33113335/

6. Shin T, Hiraoka Y, Yamasaki T, Marth JD, Penninger JM, Kanai-Azuma M, Tanaka K, Kofuji S, Nishina H. MKK7-deficiency in mature neurons impairs parental behavior in mice. Genes Cells. 2020 Oct 23. doi: 10.1111/gtc.12816. Epub ahead of print. PMID: 33098150. https://pubmed.ncbi.nlm.nih.gov/33098150/

Oct 26, Pubcrawler Hits:

1. Sharifkhodaei Z, Auld VJ. Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association. Genome. 2020 Oct 16:1-12. doi: 10.1139/gen-2020-0026. Epub ahead of print. PMID: 33064024. https://pubmed.ncbi.nlm.nih.gov/33064024/

2. Hoiland RL, Fergusson NA, Mitra AR, Griesdale DEG, Devine DV, Stukas S, Cooper J, Thiara S, Foster D, Chen LYC, Lee AYY, Conway EM, Wellington CL, Sekhon MS. The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19. Blood Adv. 2020 Oct 27;4(20):4981-4989. doi: 10.1182/bloodadvances.2020002623. PMID: 33057633. https://pubmed.ncbi.nlm.nih.gov/33057633/

3. Price HR, Lai D, Kim H, Wright TE, Coughtrie MWH, Collier AC. Detection and quantitation of non-steroidal anti-inflammatory drug use close to the time of birth using umbilical cord tissue. Toxicol Rep. 2020 Sep 8;7:1311-1318. doi: 10.1016/j.toxrep.2020.09.003. PMID: 33072523; PMCID: PMC7548959. https://pubmed.ncbi.nlm.nih.gov/33072523/

4. Espinet E, Gu Z, Imbusch CD, Giese NA, Buscher M, Safavi M, Weisenburger S, Klein C, Vogel V, Falcone M, Insua-Rodriguez J, Reitberger M, Thiel V, Kossi SO, Muckenhuber A, Sarai K, Lee AY, Backx E, Zarei S, Gaida MM, Rodriguez-Paredes M, Donato E, Yen HY, Eils R, Schlesner M, Pfarr N, Hackert T, Plass C, Brors B, Steiger K, Weichenhan D, Arda HE, Rooman I, Kopp JL, Strobel O, Weichert W, Sprick MR, Trumpp A. Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. Cancer Discov. 2020 Oct 15:CD-20-1202. doi: 10.1158/2159-8290.CD-20-1202. Epub ahead of print. PMID: 33060108. https://pubmed.ncbi.nlm.nih.gov/33060108/

5. Amenyogbe N, Dimitriu P, Cho P, Ruck C, Fortuno ES 3rd, Cai B, Alimenti A, Côté HCF, Maan EJ, Slogrove AL, Esser M, Marchant A, Goetghebuer T, Shannon CP, Tebbutt SJ, Kollmann TR, Mohn WW, Smolen KK. Innate Immune Responses and Gut Microbiomes Distinguish HIV-Exposed from HIV-Unexposed Children in a Population-Specific Manner. J Immunol. 2020 Oct 16:ji2000040. doi: 10.4049/jimmunol.2000040. Epub ahead of print. PMID: 33067377. https://pubmed.ncbi.nlm.nih.gov/33067377/

6. Overall CM. The HUPO High-Stringency Inventory of Humanity's Shared Human Proteome Revealed. J Proteome Res. 2020 Oct 19. doi: 10.1021/acs.jproteome.0c00794. Epub ahead of print. PMID: 33074000. https://pubmed.ncbi.nlm.nih.gov/33074000/

7. Adhikari S, Nice EC, Deutsch EW, Lane L, Omenn GS, Pennington SR, Paik YK, Overall CM, Corrales FJ, Cristea IM, Van Eyk JE, Uhlén M, Lindskog C, Chan DW, Bairoch A, Waddington JC, Justice JL, LaBaer J, Rodriguez H, He F, Kostrzewa M, Ping P, Gundry RL, Stewart P, Srivastava S, Srivastava S, Nogueira FCS, Domont GB, Vandenbrouck Y, Lam MPY, Wennersten S, Vizcaino JA, Wilkins M, Schwenk JM, Lundberg E, Bandeira N, Marko-Varga G, Weintraub ST, Pineau C, Kusebauch U, Moritz RL, Ahn SB, Palmblad M, Snyder MP, Aebersold R, Baker MS. A high-stringency blueprint of the human proteome. Nat Commun. 2020 Oct 16;11(1):5301. doi: 10.1038/s41467-020-19045-9. PMID: 33067450; PMCID: PMC7568584. https://pubmed.ncbi.nlm.nih.gov/33067450/

8. Genovese I, Giamogante F, Barazzuol L, Battista T, Fiorillo A, Vicario M, D'Alessandro G, Cipriani R, Limatola C, Rossi D, Sorrentino V, Poser E, Mosca L, Squitieri F, Perluigi M, Arena A, van Petegem F, Tito C, Fazi F, Giorgi C, Calì T, Ilari A, Colotti G. Sorcin is an early marker of neurodegeneration, Ca²⁺ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases. Cell Death Dis. 2020 Oct 15;11(10):861. doi: 10.1038/s41419-020-03063-y. PMID: 33060591; PMCID: PMC7566454. https://pubmed.ncbi.nlm.nih.gov/33060591/

9. Teves SS. Function through absence: Active RNA exclusion from chromosomes leads to proper cell division. J Cell Biol. 2020 Nov 2;219(11):e202009193. doi: 10.1083/jcb.202009193. PMID: 33053169. https://pubmed.ncbi.nlm.nih.gov/33053169/

10. Sexton DL, Tocheva EI. Ultrastructure of Exospore Formation in Streptomyces Revealed by Cryo-Electron Tomography. Front Microbiol. 2020 Sep 24;11:581135. doi: 10.3389/fmicb.2020.581135. PMID: 33072052; PMCID: PMC7541840. https://pubmed.ncbi.nlm.nih.gov/33072052/

Oct 19, Pubcrawler Hits:

1. Sage AP, Ng KW, Marshall EA, Stewart GL, Minatel BC, Enfield KSS, Martin SD, Brown CJ, Abraham N, Lam WL. Assessment of long non-coding RNA expression reveals novel mediators of the lung tumour immune response. Sci Rep. 2020 Oct 9;10(1):16945. doi: 10.1038/s41598-020-73787-6. PMID: 33037279. https://pubmed.ncbi.nlm.nih.gov/33037279/

2. Hadjesfandiari N, Levin E, Serrano K, Yi QL, Devine DV. Risk analysis of transfusion of cryoprecipitate without consideration of ABO group. Transfusion. 2020 Oct 10. doi: 10.1111/trf.16125. Epub ahead of print. PMID: 33037661. https://pubmed.ncbi.nlm.nih.gov/33037661/

3. Shapira T, Rankine-Wilson L, Chao JD, Pichler V, Rens C, Pfeifer T, Av-Gay Y. High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosis. Front Microbiol. 2020 Sep 18;11:553962. doi: 10.3389/fmicb.2020.553962. PMID: 33042061; PMCID: PMC7530171. https://pubmed.ncbi.nlm.nih.gov/33042061/

Oct 12, Pubcrawler Hits:

1. Behroozian S, Svensson SL, Li LY, Davies JE. Broad-Spectrum Antimicrobial and Antibiofilm Activity of a Natural Clay Mineral from British Columbia, Canada. mBio. 2020 Oct 6;11(5):e02350-20. doi: 10.1128/mBio.02350-20. PMID: 33024043. https://pubmed.ncbi.nlm.nih.gov/33024043/

Oct 5, Pubcrawler Hits:

1. Ayala-Muñoz D, Simister R, Crowe S, Macalady J, Burgos WD. Functional redundancy imparts process stability to acidic Fe(II)-oxidizing microbial reactors. Environ Microbiol. 2020 Sep 29. doi: 10.1111/1462-2920.15259. Epub ahead of print. PMID: 32996242. https://pubmed.ncbi.nlm.nih.gov/32996242/

2. Fetherolf MM, Levy-Booth DJ, Navas LE, Liu J, Grigg JC, Wilson A, Katahira R, Beckham GT, Mohn WW, Eltis LD. Characterization of alkylguaiacol-degrading cytochromes P450 for the biocatalytic valorization of lignin. Proc Natl Acad Sci U S A. 2020 Sep 28:201916349. doi: 10.1073/pnas.1916349117. Epub ahead of print. PMID: 32989155. https://pubmed.ncbi.nlm.nih.gov/32989155/

3. M A Basher AR, McLaughlin RJ, Hallam SJ. Metabolic pathway inference using multi-label classification with rich pathway features. PLoS Comput Biol. 2020 Oct 1;16(10):e1008174. doi: 10.1371/journal.pcbi.1008174. PMID: 33001968. https://pubmed.ncbi.nlm.nih.gov/33001968/

4. Brink KS, Wu P, Chuong CM, Richman JM. The Effects of Premature Tooth Extraction and Damage on Replacement Timing in the Green Iguana. Integr Comp Biol. 2020 Jul 6:icaa099. doi: 10.1093/icb/icaa099. Epub ahead of print. PMID: 32974642. https://pubmed.ncbi.nlm.nih.gov/32974642/

5. Xiong R, Sugioka K. Improved 3D cellular morphometry of Caenorhabditis elegans embryos using a refractive index matching medium. PLoS One. 2020 Sep 30;15(9):e0238955. doi: 10.1371/journal.pone.0238955. PMID: 32997668. https://pubmed.ncbi.nlm.nih.gov/32997668/

6. Hasan Ali O, Bomze D, Risch L, Brugger SD, Paprotny M, Weber M, Thiel S, Kern L, Albrich WC, Kohler P, Kahlert CR, Vernazza P, Bühler PK, Schüpbach RA, Gómez-Mejia A, Popa AM, Bergthaler A, Penninger JM, Flatz L. Severe COVID-19 is associated with elevated serum IgA and antiphospholipid IgA-antibodies. Clin Infect Dis. 2020 Sep 30:ciaa1496. doi: 10.1093/cid/ciaa1496. Epub ahead of print. PMID: 32997739. https://pubmed.ncbi.nlm.nih.gov/32997739/

Sep 28, Pubcrawler Hits:

1. Ooshio T, Yamamoto M, Fujii K, Xin B, Watanabe K, Goto M, Okada Y, Suzuki A, Penninger JM, Nishina H, Nishikawa Y. Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury. Hepatology. 2020 Sep 23. doi: 10.1002/hep.31565. Epub ahead of print. PMID: 32969030. https://pubmed.ncbi.nlm.nih.gov/32969030/

Sep 21, Pubcrawler Hits:

1. Shirane K, Miura F, Ito T, Lorincz MC. NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing. Nat Genet. 2020 Sep 14. doi: 10.1038/s41588-020-0689-z. Epub ahead of print. PMID: 32929285. https://pubmed.ncbi.nlm.nih.gov/32929285/

2. Terrado M, Okon M, McIntosh LP, Plettner E. Ligand- and pH-Induced Structural Transition of Gypsy Moth Lymantria dispar Pheromone-Binding Protein 1 (LdisPBP1). Biochemistry. 2020 Sep 11. doi: 10.1021/acs.biochem.0c00592. Epub ahead of print. PMID: 32877603. https://pubmed.ncbi.nlm.nih.gov/32877603/

3. Hagelkruys A, Wirnsberger G, Stadlmann J, Wöhner M, Horrer M, Vilagos B, Jonsson G, Kogler M, Tortola L, Novatchkova M, Bönelt P, Hoffmann D, Koglgruber R, Steffen U, Schett G, Busslinger M, Bergthaler A, Klein C, Penninger JM. A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans. J Exp Med. 2021 Jan 4;218(1):e20200559. doi: 10.1084/jem.20200559. PMID: 32930709. https://pubmed.ncbi.nlm.nih.gov/32930709/

Sep 14, Pubcrawler Hits:

1. Kolic J, Beet L, Overby P, Cen HH, Panzhinskiy E, Ure DR, Cross JL, Huizinga RB, Johnson JD. Differential effects of voclosporin and tacrolimus on insulin secretion from human islets. Endocrinology. 2020 Sep 7:bqaa162. doi: 10.1210/endocr/bqaa162. Epub ahead of print. PMID: 32894758. https://pubmed.ncbi.nlm.nih.gov/32894758/

2. Adams A, Vogl W. ORP9 Knockdown Delays the Maturation of Junction Related Endocytic Structures in the Testis and Leads to Impaired Sperm Release†. Biol Reprod. 2020 Sep 9:ioaa159. doi: 10.1093/biolre/ioaa159. Epub ahead of print. PMID: 32901807. https://pubmed.ncbi.nlm.nih.gov/32901807/

3. Adams A, Vogl W, Dawson C, Raverty S, Haulena M, Skoretz SA. Laryngeal and soft palate valving in the harbour seal (Phoca vitulina). J Exp Biol. 2020 Sep 6:jeb.230201. doi: 10.1242/jeb.230201. Epub ahead of print. PMID: 32895326. https://pubmed.ncbi.nlm.nih.gov/32895326/

Sep 7, Pubcrawler Hits:

1. Francia V, Schiffelers RM, Cullis PR, Witzigmann D. The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy. Bioconjug Chem. 2020 Aug 31. doi: 10.1021/acs.bioconjchem.0c00366. Epub ahead of print. PMID: 32786370. https://pubmed.ncbi.nlm.nih.gov/32786370/

2. Jara MA, Werneck-De-Castro JP, Lubaczeuski C, Johnson JD, Bernal-Mizrachi E. Pancreatic and duodenal homeobox-1 (PDX1) contributes to β-cell mass expansion and proliferation induced by Akt/PKB pathway. Islets. 2020 Mar 3;12(2):32-40. doi: 10.1080/19382014.2020.1762471. PMID: 32876522. https://pubmed.ncbi.nlm.nih.gov/32876522/

3. Majewski DD, Okon M, Heinkel F, Robb CS, Vuckovic M, McIntosh LP, Strynadka NCJ. Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure. 2020 Aug 27:S0969-2126(20)30288-4. doi: 10.1016/j.str.2020.08.006. Epub ahead of print. PMID: 32877645. https://pubmed.ncbi.nlm.nih.gov/32877645/

4. Ibarra Moreno CA, Kraeva N, Zvaritch E, Figueroa L, Rios E, Biesecker L, Van Petegem F, Hopkins PM, Riazi S. A multi-dimensional analysis of genotype-phenotype discordance in malignant hyperthermia susceptibility. Br J Anaesth. 2020 Aug 26:S0007-0912(20)30633-4. doi: 10.1016/j.bja.2020.07.042. Epub ahead of print. PMID: 32861507. https://pubmed.ncbi.nlm.nih.gov/32861507/

5. O'Leary TP, Sullivan KE, Wang L, Clements J, Lemire AL, Cembrowski MS. Extensive and spatially variable within-cell-type heterogeneity across the basolateral amygdala. Elife. 2020 Sep 1;9:e59003. doi: 10.7554/eLife.59003. Epub ahead of print. PMID: 32869744. https://pubmed.ncbi.nlm.nih.gov/32869744/

Aug 31, Pubcrawler Hits:

1. Curtis SB, Molday LL, Garces FA, Molday RS. Functional Analysis and Classification of Homozygous and Hypomorphic ABCA4 Variants Associated with Stargardt Macular Degeneration. Hum Mutat. 2020 Aug 26. doi: 10.1002/humu.24100. Epub ahead of print. PMID: 32845050. https://pubmed.ncbi.nlm.nih.gov/32845050/

2. Thompson DA, Iannaccone A, Ali RR, Arshavsky VY, Audo I, Bainbridge JWB, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Dalkara D, Duncan JL, Fahim AT, Flannery JG, Gattegna R, Heckenlively JR, Heon E, Jayasundera KT, Khan NW, Klassen H, Leroy BP, Molday RS, Musch DC, Pennesi ME, Petersen-Jones SM, Pierce EA, Rao RC, Reh TA, Sahel JA, Sharon D, Sieving PA, Strettoi E, Yang P, Zacks DN; Monaciano Consortium. Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium. Transl Vis Sci Technol. 2020 Jun 3;9(7):2. doi: 10.1167/tvst.9.7.2. PMID: 32832209; PMCID: PMC7414644. https://pubmed.ncbi.nlm.nih.gov/32832209/

3. Noël G, Tham DKL, Guadagno E, MacVicar B, Moukhles H. The Laminin-Induced Phosphorylation of PKCδ Regulates AQP4 Distribution and Water Permeability in Rat Astrocytes. Cell Mol Neurobiol. 2020 Aug 26. doi: 10.1007/s10571-020-00944-w. Epub ahead of print. PMID: 32851539. https://pubmed.ncbi.nlm.nih.gov/32851539/

4. Morell M, Vogl AW, IJsseldijk LL, Piscitelli-Doshkov M, Tong L, Ostertag S, Ferreira M, Fraija-Fernandez N, Colegrove KM, Puel JL, Raverty SA, Shadwick RE. Echolocating Whales and Bats Express the Motor Protein Prestin in the Inner Ear: A Potential Marker for Hearing Loss. Front Vet Sci. 2020 Jul 17;7:429. doi: 10.3389/fvets.2020.00429. PMID: 32851016; PMCID: PMC7396497. https://pubmed.ncbi.nlm.nih.gov/32851016/

5. Ming J, Cronin SJF, Penninger JM. Targeting the RANKL/RANK/OPG Axis for Cancer Therapy. Front Oncol. 2020 Aug 7;10:1283. doi: 10.3389/fonc.2020.01283. PMID: 32850393; PMCID: PMC7426519. https://pubmed.ncbi.nlm.nih.gov/32850393/

6. Nitta T, Tsutsumi M, Nitta S, Muro R, Suzuki EC, Nakano K, Tomofuji Y, Sawa S, Okamura T, Penninger JM, Takayanagi H. Fibroblasts as a source of self-antigens for central immune tolerance. Nat Immunol. 2020 Aug 24. doi: 10.1038/s41590-020-0756-8. Epub ahead of print. PMID: 32839611. https://pubmed.ncbi.nlm.nih.gov/32839611/

Aug 24, Pubcrawler Hits:

1. Chamberlain TC, Cheung ST, Yoon JSJ, Ming-Lum A, Gardill BR, Shakibakho S, Dzananovic E, Ban F, Samiea A, Jawanda K, Priatel J, Krystal G, Ong CJ, Cherkasov A, Andersen RJ, McKenna SA, Van Petegem F, Mui AL. Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes. iScience. 2020 Aug 21;23(8):101433. doi: 10.1016/j.isci.2020.101433. Epub 2020 Aug 2. PMID: 32823063. https://pubmed.ncbi.nlm.nih.gov/32823063/

2. Ma R, Haji-Ghassemi O, Ma D, Jiang H, Lin L, Yao L, Samurkas A, Li Y, Wang Y, Cao P, Wu S, Zhang Y, Murayama T, Moussian B, Van Petegem F, Yuchi Z. Structural basis for diamide modulation of ryanodine receptor. Nat Chem Biol. 2020 Aug 17. doi: 10.1038/s41589-020-0627-5. Epub ahead of print. PMID: 32807966. https://pubmed.ncbi.nlm.nih.gov/32807966/

Aug 17, Pubcrawler Hits:

1. Conway EM, Pryzdial ELG. Is the COVID-19 thrombotic catastrophe complement-connected? J Thromb Haemost. 2020 Aug 6. doi: 10.1111/jth.15050. Epub ahead of print. PMID: 32762081. https://pubmed.ncbi.nlm.nih.gov/32762081/

2. Liu MM, Coleman S, Wilkinson L, Smith ML, Hoang T, Niyah N, Mukherjee M, Huynh S, Parker CT, Kovac J, Hancock REW, Gaynor EC. Unique inducible filamentous motility identified in pathogenic Bacillus cereus group species. ISME J. 2020 Aug 7. doi: 10.1038/s41396-020-0728-x. Epub ahead of print. PMID: 32770116. https://pubmed.ncbi.nlm.nih.gov/32770116/

3. Hedil M, Nakasu EYT, Nagata T, Wen J, Jan E, Michereff-Filho M, Inoue-Nagata AK. New features on the genomic organization of a novel dicistrovirus identified from the sweet potato whitefly Bemisia tabaci. Virus Res. 2020 Aug 7:198112. doi: 10.1016/j.virusres.2020.198112. Epub ahead of print. PMID: 32777388. https://pubmed.ncbi.nlm.nih.gov/32777388/

4. Chan ACK, Lin H, Koch D, Grass G, Nies DH, Murphy MEP. A copper site is required for iron transport by the periplasmic proteins P19 and FetP. Metallomics. 2020 Aug 11. doi: 10.1039/d0mt00130a. Epub ahead of print. PMID: 32780051. https://pubmed.ncbi.nlm.nih.gov/32780051/

5. Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, Matsushita M, Ara T, Yasuda H, Penninger JM, Takahashi N, Udagawa N, Kobayashi Y. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020 Aug 13;10(1):13751. doi: 10.1038/s41598-020-70817-1. PMID: 32792620. https://pubmed.ncbi.nlm.nih.gov/32792620/

Aug 10, Pubcrawler Hits:

1. Conley AJ, Place N, Legacki E, Hammond GL, Cunha GR, Drea CM, Weldele ML, Glickman SE. Spotted hyaenas and the sexual spectrum: reproductive endocrinology and development. J Endocrinol. 2020 Aug 1:JOE-20-0252.R1. doi: 10.1530/JOE-20-0252. Epub ahead of print. PMID: 32755997. https://pubmed.ncbi.nlm.nih.gov/32755997/

2. Satti S, Deng P, Matthews K, Duffy SP, Ma H. Multiplexed end-point microfluidic chemotaxis assay using centrifugal alignment. Lab Chip. 2020 Aug 4. doi: 10.1039/d0lc00311e. Epub ahead of print. PMID: 32748936. https://pubmed.ncbi.nlm.nih.gov/32748936/

Aug 3, Pubcrawler Hits:

1. Perez SEI, Hahn AS, Krzywinski M, Hallam SJ. Hive Panel Explorer: an interactive network visualization tool. Bioinformatics. 2020 Jul 27:btaa683. doi: 10.1093/bioinformatics/btaa683. Epub ahead of print. PMID: 32717050. https://pubmed.ncbi.nlm.nih.gov/32717050/

2. Botezelli JD, Overby P, Lindo L, Wang S, Haïda O, Lim GE, Templeman NM, Pauli JR, Johnson JD. Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice. Am J Physiol Endocrinol Metab. 2020 Jul 27. doi: 10.1152/ajpendo.00128.2020. Epub ahead of print. PMID: 32715748. https://pubmed.ncbi.nlm.nih.gov/32715748/

3. Rebollo R, Galvão-Ferrarini M, Gagnier L, Zhang Y, Ferraj A, Beck CR, Lorincz MC, Mager DL. Inter-Strain Epigenomic Profiling Reveals a Candidate IAP Master Copy in C3H Mice. Viruses. 2020 Jul 21;12(7):E783. doi: 10.3390/v12070783. PMID: 32708087. https://pubmed.ncbi.nlm.nih.gov/32708087/

4. Millar D, Hayes C, Jones J, Klapper E, Kniep JN, Luu HS, Noland DK, Petitti L, Poisson JL, Spaepen E, Ye Z, Maurer-Spurej E. Comparison of the platelet activation status of single-donor platelets obtained with two different cell separator technologies. Transfusion. 2020 Jul 29. doi: 10.1111/trf.15934. Epub ahead of print. PMID: 32729161. https://pubmed.ncbi.nlm.nih.gov/32729161/

5. Khosla K, Naus CC, Sin WC. Cx43 in Neural Progenitors Promotes Glioma Invasion in a 3D Culture System. Int J Mol Sci. 2020 Jul 23;21(15):E5216. doi: 10.3390/ijms21155216. PMID: 32717889. https://pubmed.ncbi.nlm.nih.gov/32717889/

July 27, Pubcrawler Hits:

1. Strilchuk AW, Meixner SC, Leung J, Safikhan N, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens Iii AP, Palumbo J, Conway EM, Pryzdial EL, Cullis P, Kastrup CJ. Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency. Blood. 2020 Jul 17:blood.2020004976. doi: 10.1182/blood.2020004976. Epub ahead of print. PMID: 32678423. https://pubmed.ncbi.nlm.nih.gov/32678423/

2. Haw J, Polzer J, Devine DV. Emotional labour and cord blood collection: frontline perspectives. J Health Organ Manag. 2020 Jun 9;34(5):587-601. doi: 10.1108/JHOM-10-2019-0305. PMID: 32681634. https://pubmed.ncbi.nlm.nih.gov/32681634/

3. Stanley M, McDowell SAT, Gordon MD. A fly rhodopsin sheds light on thermal taste. Cell Calcium. 2020 Nov;91:102259. doi: 10.1016/j.ceca.2020.102259. Epub 2020 Jul 27. PMID: 32739609. https://pubmed.ncbi.nlm.nih.gov/32739609/

4. Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M. Antiviral anticoagulation. Res Pract Thromb Haemost. 2020 Jul 6;4(5):774-788. doi: 10.1002/rth2.12406. PMID: 32685886; PMCID: PMC7354393. https://pubmed.ncbi.nlm.nih.gov/32685886/

5. Appelberg S, Gupta S, Akusjärvi SS, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, Krishnan S, Singh K, Penninger JM, Mirazimi A, Neogi U. Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells. Emerg Microbes Infect. 2020 Jul 21:1-36. doi: 10.1080/22221751.2020.1799723. Epub ahead of print. PMID: 32691695. https://pubmed.ncbi.nlm.nih.gov/32691695/

6. Thompson E, Eldstrom J, Fedida D. Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels. Annu Rev Pharmacol Toxicol. 2020 Jul 15. doi: 10.1146/annurev-pharmtox-010919-023645. Epub ahead of print. PMID: 32667860. https://pubmed.ncbi.nlm.nih.gov/32667860/

July 13, Pubcrawler Hits:

1. Witzigmann D, Kulkarni JA, Leung J, Chen S, Cullis PR, van der Meel R. Lipid nanoparticle technology for therapeutic gene regulation in the liver. Adv Drug Deliv Rev. 2020 Jul 1:S0169-409X(20)30072-7. doi: 10.1016/j.addr.2020.06.026. Epub ahead of print. PMID: 32622021; PMCID: PMC7329694. https://pubmed.ncbi.nlm.nih.gov/32622021/

2. Morgan-Lang C, McLaughlin R, Armstrong Z, Zhang G, Chan K, Hallam SJ. TreeSAPP: The Tree-based Sensitive and Accurate Phylogenetic Profiler. Bioinformatics. 2020 Jul 8:btaa588. doi: 10.1093/bioinformatics/btaa588. Epub ahead of print. PMID: 32637989. https://pubmed.ncbi.nlm.nih.gov/32637989/

3. Lee J, Kim K, Cho JH, Bae JY, O'Leary TP, Johnson JD, Bae YC, Kim EK. Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production. JCI Insight. 2020 Jul 9:135412. doi: 10.1172/jci.insight.135412. Epub ahead of print. PMID: 32644973. https://pubmed.ncbi.nlm.nih.gov/32644973/

4. Drayton M, Kizhakkedathu JN, Straus SK. Towards Robust Delivery of Antimicrobial Peptides to Combat Bacterial Resistance. Molecules. 2020 Jul 3;25(13):E3048. doi: 10.3390/molecules25133048. PMID: 32635310. https://pubmed.ncbi.nlm.nih.gov/32635310/

5. Khadilkar RJ, Ho KYL, Venkatesh B, Tanentzapf G. Integrins Modulate Extracellular Matrix Organization to Control Cell Signaling during Hematopoiesis. Curr Biol. 2020 Jul 4:S0960-9822(20)30843-5. doi: 10.1016/j.cub.2020.06.027. Epub ahead of print. PMID: 32649911. https://pubmed.ncbi.nlm.nih.gov/32649911/

6. Chabloz A, Schaefer JV, Kozieradzki I, Cronin SJF, Strebinger D, Macaluso F, Wald J, Rabbitts TH, Plückthun A, Marlovits TC, Penninger JM. Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol. Commun Biol. 2020 Jul 3;3(1):342. doi: 10.1038/s42003-020-1072-4. PMID: 32620833; PMCID: PMC7335062. https://pubmed.ncbi.nlm.nih.gov/32620833/

July 6, Pubcrawler Hits:

1. MacGillivray RTA, Conway EM. Obituary for Earl Warren Davie 1927-2020. J Thromb Haemost. 2020 Jun 30. doi: 10.1111/jth.14978. Epub ahead of print. PMID: 32608042. https://pubmed.ncbi.nlm.nih.gov/32608042/

2. Szeinbaum N, Nunn BL, Cavazos AR, Crowe SA, Stewart FJ, DiChristina TJ, Reinhard CT, Glass JB. Novel insights into the taxonomic diversity and molecular mechanisms of bacterial Mn(III) reduction. Environ Microbiol Rep. 2020 Jul 2. doi: 10.1111/1758-2229.12867. Epub ahead of print. PMID: 32613749. https://pubmed.ncbi.nlm.nih.gov/32613749/

3. Ramzy A, Tudurí E, Glavas MM, Baker RK, Mojibian M, Fox JK, O'Dwyer SM, Dai D, Hu X, Denroche HC, Edeer N, Gray SL, Verchere CB, Johnson JD, Kieffer TJ. AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects. Sci Rep. 2020 Jun 29;10(1):10518. doi: 10.1038/s41598-020-67136-w. PMID: 32601405; PMCID: PMC7324556. https://pubmed.ncbi.nlm.nih.gov/32601405/

4. Achazi K, Haag R, Ballauff M, Dernedde J, Kizhakkedathu JN, Maysinger D, Multhaup G. Understanding the interaction of polyelectrolyte architectures with proteins and biosystems. Angew Chem Int Ed Engl. 2020 Jun 26. doi: 10.1002/anie.202006457. Epub ahead of print. PMID: 32589355. https://pubmed.ncbi.nlm.nih.gov/32589355/

5. Duncan MC, Onguéné PA, Kihara I, Nebangwa DN, Naidu ME, Williams DE, Balgi AD, Andrae-Marobela K, Roberge M, Andersen RJ, Niikura M, Ntie-Kang F, Tietjen I. Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus. Molecules. 2020 Jun 24;25(12):E2903. doi: 10.3390/molecules25122903. PMID: 32599753. https://pubmed.ncbi.nlm.nih.gov/32599753/

June 29, Pubcrawler Hits:

1. Accili E. An ion channel in the company of a transporter. J Gen Physiol. 2020 Jul 6;152(7):e202012590. doi: 10.1085/jgp.202012590. PMID: 32579683. https://pubmed.ncbi.nlm.nih.gov/32579683/

2. Wang Y, Eldstrom J, Fedida D. Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes. Front Physiol. 2020 Jun 4;11:504. doi: 10.3389/fphys.2020.00504. PMID: 32581825; PMCID: PMC7287213. https://pubmed.ncbi.nlm.nih.gov/32581825/

3. Haage A, Wagner K, Deng W, Venkatesh B, Mitchell C, Goodwin K, Bogutz A, Lefebvre L, Van Raamsdonk CD, Tanentzapf G. Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development. Development. 2020 Jun 24:dev.184234. doi: 10.1242/dev.184234. Epub ahead of print. PMID: 32580934. https://pubmed.ncbi.nlm.nih.gov/32580934/

4. Nabi IR. Biography-Ivan Robert Nabi. Cancer Metastasis Rev. 2020 Jun;39(2):333. doi: 10.1007/s10555-020-09893-8. PMID: 32577925. https://pubmed.ncbi.nlm.nih.gov/32577925/

5. Falkowski K, Bielecka E, Thøgersen IB, Bocheńska O, Płaza K, Kalińska M, Sąsiadek L, Magoch M, Pęcak A, Wiśniewska M, Gruba N, Wysocka M, Wojtysiak A, Brzezińska-Bodal M, Sychowska K, Pejkovska A, Rehders M, Butler G, Overall CM, Brix K, Dubin G, Lesner A, Kozik A, Enghild JJ, Potempa J, Kantyka T. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. Int J Mol Sci. 2020 Jun 19;21(12):E4383. doi: 10.3390/ijms21124383. PMID: 32575583. https://pubmed.ncbi.nlm.nih.gov/32575583/

June 22, Pubcrawler Hits:

1. Bárdy P, Füzik T, Hrebík D, Pantůček R, Thomas Beatty J, Plevka P. Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun. 2020 Jun 15;11(1):3034. doi: 10.1038/s41467-020-16669-9. PMID: 32541663; PMCID: PMC7296036. https://pubmed.ncbi.nlm.nih.gov/32541663/

2. Al-Riyami AZ, Schäfer R, van der Berg K, Bloch EM, Escourt LJ, Goel R, Hindawi S, Josephson CD, Land K, McQuilten ZK, Spitalnik SL, Wood EM, Devine DV, So-Osman C; ISBT Convalescent Plasma Working Group. Clinical use of Convalescent Plasma in the COVID-19 pandemic; a transfusion-focussed gap analysis with recommendations for future research priorities. Vox Sang. 2020 Jun 15. doi: 10.1111/vox.12973. Epub ahead of print. PMID: 32542847. https://pubmed.ncbi.nlm.nih.gov/32542847/

3. Bloch EM, Goel R, Wendel S, Burnouf T, Al-Riyami AZ, Ang AL, DeAngelis V, Dumont LJ, Land K, Lee CK, Oreh A, Patidar G, Spitalnik SL, Vermeulen M, Hindawi S, Van den Berg K, Tiberghien P, Vrielink H, Young P, Devine D, So-Osman C; ISBT Convalescent Plasma Working Group. Guidance for the Procurement of COVID-19 Convalescent Plasma: Differences between High and Low-Middle Income Countries. Vox Sang. 2020 Jun 13. doi: 10.1111/vox.12970. Epub ahead of print. PMID: 32533868. https://pubmed.ncbi.nlm.nih.gov/32533868/

4. Kerr CH, Skinnider MA, Andrews DDT, Madero AM, Chan QWT, Stacey RG, Stoynov N, Jan E, Foster LJ. Dynamic rewiring of the human interactome by interferon signaling. Genome Biol. 2020 Jun 15;21(1):140. doi: 10.1186/s13059-020-02050-y. PMID: 32539747; PMCID: PMC7294662. https://pubmed.ncbi.nlm.nih.gov/32539747/

5. Abbina S, Takeuchi LE, Anilkumar P, Yu K, Rogalski JC, Shenoi RA, Constantinescu I, Kizhakkedathu JN. Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface. Nat Commun. 2020 Jun 16;11(1):3048. doi: 10.1038/s41467-020-16772-x. PMID: 32546688. https://pubmed.ncbi.nlm.nih.gov/32546688/

6. Hendi A, Mizumoto K. GFPnovo2, a brighter GFP variant for in vivo labeling in C. elegans. MicroPubl Biol. 2018 Sep 6;2018:10.17912/49YB-7K39. doi: 10.17912/49YB-7K39. PMID: 32550394; PMCID: PMC7282520. https://pubmed.ncbi.nlm.nih.gov/32550394/

7. Tsai K, Huang YH, Ma C, Baldwin TA, Harder KW, Vallance BA, Priatel JJ. Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen. J Immunol. 2020 Jun 15:ji1900687. doi: 10.4049/jimmunol.1900687. Epub ahead of print. PMID: 32540993. https://pubmed.ncbi.nlm.nih.gov/32540993/

June 15, Pubcrawler Hits:

1. Devine DV. SARS in Canada: Lessons learned for the blood operator. Transfus Med. 2020 Jun;30(3):172-173. doi: 10.1111/tme.12699. PMID: 32529741; PMCID: PMC7276835. https://pubmed.ncbi.nlm.nih.gov/32529741/?dopt=Abstract

2. Horianopoulos LC, Hu G, Caza M, Schmitt K, Overby P, Johnson JD, Valerius O, Braus GH, Kronstad JW. The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans. mBio. 2020 Jun 9;11(3):e01127-20. doi: 10.1128/mBio.01127-20. PMID: 32518190. https://pubmed.ncbi.nlm.nih.gov/32518190/?dopt=Abstract

3. Refaeli I, Hughes MR, Wong AK, Bissonnette MLZ, Roskelley CD, Vogl WA, Barbour SJ, Freedman BS, McNagny KM. Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease. Sci Rep. 2020 Jun 10;10(1):9419. doi: 10.1038/s41598-020-64907-3. PMID: 32523052. https://pubmed.ncbi.nlm.nih.gov/32523052/?dopt=Abstract

4. Alexander JAN, Radaeva M, King DT, Chambers HF, Cherkasov A, Chatterjee SS, Strynadka NCJ. -Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus. J Biol Chem. 2020 Jun 9:jbc.RA120.013029. doi: 10.1074/jbc.RA120.013029. Epub ahead of print. PMID: 32518158. https://pubmed.ncbi.nlm.nih.gov/32518158/?dopt=Abstract

June 8, Pubcrawler Hits:

1. Marshall NC, Thejoe M, Klein T, Serapio-Palacios A, Santos AS, von Krosigk N, Kizhakkedathu JN, Stoynov N, Foster LJ, Overall CM, Finlay BB. Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death. mSystems. 2020 Jun 2;5(3):e00283-20. doi: 10.1128/mSystems.00283-20. PMID: 32487743. https://pubmed.ncbi.nlm.nih.gov/32487743/?dopt=Abstract

2. Young BP, Post KL, Chao JT, Meili F, Haas K, Loewen CJR. Sentinel Interaction Mapping (SIM) - A generic approach for the functional analysis of human disease gene variants using yeast. Dis Model Mech. 2020 May 29:dmm.044560. doi: 10.1242/dmm.044560. Epub ahead of print. PMID: 32471850. https://pubmed.ncbi.nlm.nih.gov/32471850/?dopt=Abstract

3. Rufenach B, Christy D, Flucher BE, Bui JM, Gsponer J, Campiglio M, Van Petegem F. Multiple Sequence Variants in STAC3 Affect Interactions with Ca_V1.1 and Excitation-Contraction Coupling. Structure. 2020 May 27:S0969-2126(20)30174-X. doi: 10.1016/j.str.2020.05.005. Epub ahead of print. PMID: 32492370. https://pubmed.ncbi.nlm.nih.gov/32492370/?dopt=Abstract

June 1, Pubcrawler Hits:

1. Davies JE. In memory of Professor Arnold L. Demain. J Antibiot (Tokyo). 2020 May 28. doi: 10.1038/s41429-020-0325-2. Epub ahead of print. PMID: 32461629. https://pubmed.ncbi.nlm.nih.gov/32461629/?dopt=Abstract

2. Shim YA, Campbell T, Weliwitigoda A, Dosanjh M, Johnson P. Regulation of CD71⁺TER119⁺ erythroid progenitor cells by CD45. Exp Hematol. 2020 May 22:S0301-472X(20)30182-X. doi: 10.1016/j.exphem.2020.05.005. Epub ahead of print. PMID: 32450207. https://pubmed.ncbi.nlm.nih.gov/32450207/?dopt=Abstract

3. Ahmadabadi HY, Yu K, Kizhakkedathu JN. Surface modification approaches for prevention of implant associated infections. Colloids Surf B Biointerfaces. 2020 May 12;193:111116. doi: 10.1016/j.colsurfb.2020.111116. Epub ahead of print. PMID: 32447202. https://pubmed.ncbi.nlm.nih.gov/32447202/?dopt=Abstract

4. Jain F, Longakit A, Huang JL, Van Raamsdonk CD. Endothelin signaling promotes melanoma tumorigenesis driven by constitutively active GNAQ. Pigment Cell Melanoma Res. 2020 May 26. doi: 10.1111/pcmr.12900. Epub ahead of print. PMID: 32453908. https://pubmed.ncbi.nlm.nih.gov/32453908/?dopt=Abstract

5. Vogel Ciernia A, Link VM, Careaga M, LaSalle J, Ashwood P. Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages. Brain Behav Immun. 2020 May 23:S0889-1591(20)30260-9. doi: 10.1016/j.bbi.2020.05.058. Epub ahead of print. PMID: 32454135. https://pubmed.ncbi.nlm.nih.gov/32454135/?dopt=Abstract

May 25, Pubcrawler Hits:

1. Phipps SM, Garry CE, Kamal S, Johnson JD, Gilmer J, Long A, Kelleher D, Duggan SP. High Content Imaging of Barrett's-Associated High Grade Dysplasia Cells Following siRNA Library Screening Reveals Acid Responsive Regulators of Cellular Transitions. Cell Mol Gastroenterol Hepatol. 2020 May 13:S2352-345X(20)30072-2. doi: 10.1016/j.jcmgh.2020.05.002. Epub ahead of print. PMID: 32416156. https://pubmed.ncbi.nlm.nih.gov/32416156/?dopt=Abstract

2. Adak T, Morales DL, Cook AJ, Grigg JC, Murphy MEP, Tanner ME. ArnD is a deformylase involved in polymyxin resistance. Chem Commun (Camb). 2020 May 20. doi: 10.1039/d0cc02241a. Epub ahead of print. PMID: 32432293. https://pubmed.ncbi.nlm.nih.gov/32432293/?dopt=Abstract

3. Nabi IR. Preface. Cancer Metastasis Rev. 2020 May 16. doi: 10.1007/s10555-020-09894-7. Epub ahead of print. PMID: 32417991. https://pubmed.ncbi.nlm.nih.gov/32417991/?dopt=Abstract

4. Hughes MR, Hernaez DC, Cait J, Refaeli I, Lo B, Roskelley C, McNagny KM. A Sticky Wicket: Defining Molecular Functions for CD34 in Hematopoietic Cells. Exp Hematol. 2020 May 15:S0301-472X(20)30181-8. doi: 10.1016/j.exphem.2020.05.004. Epub ahead of print. PMID: 32422232. https://pubmed.ncbi.nlm.nih.gov/32422232/?dopt=Abstract

5. Orthofer M, Valsesia A, Mägi R, Wang QP, Kaczanowska J, Kozieradzki I, Leopoldi A, Cikes D, Zopf LM, Tretiakov EO, Demetz E, Hilbe R, Boehm A, Ticevic M, Nõukas M, Jais A, Spirk K, Clark T, Amann S, Lepamets M, Neumayr C, Arnold C, Dou Z, Kuhn V, Novatchkova M, Cronin SJF, Tietge UJF, Müller S, Pospisilik JA, Nagy V, Hui CC, Lazovic J, Esterbauer H, Hagelkruys A, Tancevski I, Kiefer FW, Harkany T, Haubensak W, Neely GG, Metspalu A, Hager J, Gheldof N, Penninger JM. Identification of ALK in Thinness. Cell. 2020 May 13:S0092-8674(20)30497-9. doi: 10.1016/j.cell.2020.04.034. Epub ahead of print. PMID: 32442405. https://pubmed.ncbi.nlm.nih.gov/32442405/?dopt=Abstract

May 18, Pubcrawler Hits:

1. Adams A, Vogl W. Knockdown of IP3R1 Disrupts TBC-ER Contact Sites and the Morphology of Apical Processes Encapsulating Late Spermatids. Biol Reprod. 2020 May 14. pii: ioaa074. doi: 10.1093/biolre/ioaa074. [Epub ahead of print] PubMed PMID: 32406903. https://www.ncbi.nlm.nih.gov/pubmed/32406903?dopt=Abstract

May 11, Pubcrawler Hits:

1. Anilkumar P, Lawson TB, Abbina S, Mäkelä JTA, Sabatelle RC, Takeuchi LE, Snyder BD, Grinstaff MW, Kizhakkedathu JN. Mega macromolecules as single molecule lubricants for hard and soft surfaces. Nat Commun. 2020 May 1;11(1):2139. doi: 10.1038/s41467-020-15975-6. PubMed PMID: 32358489; PubMed Central PMCID: PMC7195476. https://www.ncbi.nlm.nih.gov/pubmed/32358489?dopt=Abstract

2. Chao JT, Hollman R, Meyers WM, Meili F, Matreyek KA, Dean P, Fowler DM, Haas K, Roskelley CD, Loewen CJR. A premalignant cell-based model for functionalization and classification of PTEN variants. Cancer Res. 2020 May 4. pii: canres.3278.2019. doi: 10.1158/0008-5472.CAN-19-3278. [Epub ahead of print] PubMed PMID: 32366478. https://www.ncbi.nlm.nih.gov/pubmed/32366478?dopt=Abstract

3. Worrall LJ, Hu J, Strynadka NCJ. Aligning the Symmetry of the Type III Secretion System Needle Complex. J Chem Inf Model. 2020 May 4. doi: 10.1021/acs.jcim.0c00088. [Epub ahead of print] PubMed PMID: 32293878. https://www.ncbi.nlm.nih.gov/pubmed/32293878?dopt=Abstract

4. Kogler M, Tortola L, Negri GL, Leopoldi A, El-Naggar AM, Mereiter S, Gomez Diaz C, Nitsch R, Tortora D, Kavirayani AM, Gapp BV, Rao S, Uribesalgo I, Hoffmann D, Cikes D, Novatchkova M, Williams DA, Trent JM, Ikeda F, Daugaard M, Hagelkruys A, Sorensen PH, Penninger JM. HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases. Cancer Res. 2020 May 4. pii: canres.2270.2019. doi: 10.1158/0008-5472.CAN-19-2270. [Epub ahead of print] PubMed PMID: 32366477. https://www.ncbi.nlm.nih.gov/pubmed/32366477?dopt=Abstract

May 4, Pubcrawler Hits:

1. Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K. Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun. 2020 Apr 29;11(1):2073. doi: 10.1038/s41467-020-15943-0. PubMed PMID: 32350270; PubMed Central PMCID: PMC7190743. https://www.ncbi.nlm.nih.gov/pubmed/32350270?dopt=Abstract

2. Chen CH, Lai CH, Hong YK, Lu JM, Lin SY, Lee TC, Chang LY, Ho ML, Conway EM, Wu HL, Cheng TL. Thrombomodulin functional domains support osteoblast differentiation and bone healing in diabetes in mice. J Bone Miner Res. 2020 Apr 24. doi: 10.1002/jbmr.4036. [Epub ahead of print] PubMed PMID: 32329910. https://www.ncbi.nlm.nih.gov/pubmed/32329910?dopt=Abstract

3. Erwin SR, Sun W, Copeland M, Lindo S, Spruston N, Cembrowski MS. A Sparse, Spatially Biased Subtype of Mature Granule Cell Dominates Recruitment in Hippocampal-Associated Behaviors. Cell Rep. 2020 Apr 28;31(4):107551. doi: 10.1016/j.celrep.2020.107551. PubMed PMID: 32348756. https://www.ncbi.nlm.nih.gov/pubmed/32348756?dopt=Abstract

4. Monteil V, Kwon H, Prado P, Hagelkrüys A, Wimmer RA, Stahl M, Leopoldi A, Garreta E, Hurtado Del Pozo C, Prosper F, Romero JP, Wirnsberger G, Zhang H, Slutsky AS, Conder R, Montserrat N, Mirazimi A, Penninger JM. Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2. Cell. 2020 Apr 17. pii: S0092-8674(20)30399-8. doi: 10.1016/j.cell.2020.04.004. [Epub ahead of print] PubMed PMID: 32333836; PubMed Central PMCID: PMC7181998. https://www.ncbi.nlm.nih.gov/pubmed/32333836?dopt=Abstract

Apr 27, Pubcrawler Hits:

1. Jun D, Richardson-Sanchez T, Mahey A, Murphy MEP, Fernandez RC, Beatty JT. Introduction of the Menaquinone Biosynthetic Pathway into Rhodobacter sphaeroides and de Novo Synthesis of Menaquinone for Incorporation into Heterologously Expressed Integral Membrane Proteins. ACS Synth Biol. 2020 Apr 21. doi: 10.1021/acssynbio.0c00066. [Epub ahead of print] PubMed PMID: 32271543. https://www.ncbi.nlm.nih.gov/pubmed/32271543?dopt=Abstract

2. Holt C, Hamborg L, Lau K, Brohus M, Sørensen AB, Larsen KT, Sommer C, Van Petegem F, Overgaard MT, Wimmer R. The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-domain, altering its interaction with the cardiac ryanodine receptor. J Biol Chem. 2020 Apr 21. pii: jbc.RA120.013430. doi: 10.1074/jbc.RA120.013430. [Epub ahead of print] PubMed PMID: 32317284. https://www.ncbi.nlm.nih.gov/pubmed/32317284?dopt=Abstract

3. Caveney NA, Egan AJF, Ayala I, Laguri C, Robb CS, Breukink E, Vollmer W, Strynadka NCJ, Simorre JP. Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa. Structure. 2020 Apr 9. pii: S0969-2126(20)30094-0. doi: 10.1016/j.str.2020.03.012. [Epub ahead of print] PubMed PMID: 32320673. https://www.ncbi.nlm.nih.gov/pubmed/32320673?dopt=Abstract

Apr 20, Pubcrawler Hits:

1. Ramzy A, Asadi A, Kieffer TJ. Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 But Not PC2. Diabetes. 2020 Apr 14. pii: db190276. doi: 10.2337/db19-0276. [Epub ahead of print] PubMed PMID: 32291281. https://www.ncbi.nlm.nih.gov/pubmed/32291281?dopt=Abstract

2. Tabernero A, Koulakoff A, Roux L, Venance L, Leybaert L, Sáez JC, Naus CC. Christian Giaume (November 1951-July 2019). Glia. 2020 Apr 16. doi: 10.1002/glia.23836. [Epub ahead of print] PubMed PMID: 32298009. https://www.ncbi.nlm.nih.gov/pubmed/32298009?dopt=Abstract

Apr 13, Pubcrawler Hits:

1. Hunter AC, Petley-Ragan LM, Das M, Auld VJ. Basigin associates with integrin in order to regulate perineurial glia and Drosophila nervous system morphology. J Neurosci. 2020 Apr 6. pii: JN-RM-1397-19. doi: 10.1523/JNEUROSCI.1397-19.2020. [Epub ahead of print] PubMed PMID: 32265259. https://www.ncbi.nlm.nih.gov/pubmed/32265259?dopt=Abstract

2. Déjean G, Tamura K, Cabrera A, Jain N, Pudlo NA, Pereira G, Viborg AH, Van Petegem F, Martens EC, Brumer H. Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides. mBio. 2020 Apr 7;11(2). pii: e00095-20. doi: 10.1128/mBio.00095-20. PubMed PMID: 32265336. https://www.ncbi.nlm.nih.gov/pubmed/32265336?dopt=Abstract

3. Lin BH, Sutherland MR, Rosell FI, Morrissey JH, Pryzdial ELG. Coagulation factor VIIa binds to herpes simplex virus 1-encoded glycoprotein C forming a factor X-enhanced tenase complex oriented on membranes. J Thromb Haemost. 2020 Jun;18(6):1370-1380. doi: 10.1111/jth.14790. Epub 2020 Apr 9. PMID: 32145149. https://pubmed.ncbi.nlm.nih.gov/32145149/

Apr 6, Pubcrawler Hits:

1. Jalily PH, Duncan MC, Fedida D, Wang J, Tietjen I. Put a cork in it: Plugging the M2 viral ion channel to sink influenza. Antiviral Res. 2020 Mar 27:104780. doi: 10.1016/j.antiviral.2020.104780. [Epub ahead of print] Review. PubMed PMID: 32229237; PubMed Central PMCID: PMC7102647. https://www.ncbi.nlm.nih.gov/pubmed/32229237?dopt=Abstract

2. Brind'Amour J, Lorincz MC. Setting the chromatin stage in oocytes. Nat Cell Biol. 2020 Mar 30. doi: 10.1038/s41556-020-0499-7. [Epub ahead of print] PubMed PMID: 32231308. https://www.ncbi.nlm.nih.gov/pubmed/32231308?dopt=Abstract

3. Workman SD, Strynadka NCJ. A Slippery Scaffold: Synthesis and Recycling of the Bacterial Cell Wall Carrier Lipid. J Mol Biol. 2020 Mar 28. pii: S0022-2836(20)30258-8. doi: 10.1016/j.jmb.2020.03.025. [Epub ahead of print] Review. PubMed PMID: 32234311. https://www.ncbi.nlm.nih.gov/pubmed/32234311?dopt=Abstract

Mar 30, Pubcrawler Hits:

1. Tysoe CR, Caner S, Calvert MB, Win-Mason A, Brayer GD, Withers SG. Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase. Chem Sci. 2019 Oct 18;10(48):11073-11077. doi: 10.1039/c9sc02610j. eCollection 2019 Dec 28. PubMed PMID: 32206255; PubMed Central PMCID: PMC7069248. https://www.ncbi.nlm.nih.gov/pubmed/32206255?dopt=Abstract

2. Szoták-Ajtay K, Szõke D, Kovács G, Andréka J, Brenner GB, Giricz Z, Penninger J, Kahn ML, Jakus Z. Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1 (K/K) Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth. Front Bioeng Biotechnol. 2020 Mar 6;8:136. doi: 10.3389/fbioe.2020.00136. eCollection 2020. PubMed PMID: 32211389; PubMed Central PMCID: PMC7067749. https://www.ncbi.nlm.nih.gov/pubmed/32211389?dopt=Abstract

Mar 23, Pubcrawler Hits:

1. Davies JE, Behroozian S. An ancient solution to a modern problem. Mol Microbiol. 2020 Mar;113(3):546-549. doi: 10.1111/mmi.14481. Review. PubMed PMID: 32185831. https://www.ncbi.nlm.nih.gov/pubmed/32185831?dopt=Abstract

2. Ludwig DS, Ebbeling CB, Bikman BT, Johnson JD. Testing the carbohydrate-insulin model in mice: The importance of distinguishing primary hyperinsulinemia from insulin resistance and metabolic dysfunction. Mol Metab. 2020 Feb 12:100960. doi: 10.1016/j.molmet.2020.02.003. [Epub ahead of print] PubMed PMID: 32199816. https://www.ncbi.nlm.nih.gov/pubmed/32199816?dopt=Abstract

3. Ye J, Huang A, Wang H, Zhang AMY, Huang X, Lan Q, Sato T, Goyama S, Kurokawa M, Deng C, Sander M, Schaeffer DF, Li W, Kopp JL, Xie R. PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response. Cell Death Dis. 2020 Mar 16;11(3):187. doi: 10.1038/s41419-020-2371-x. PubMed PMID: 32179733; PubMed Central PMCID: PMC7075911. https://www.ncbi.nlm.nih.gov/pubmed/32179733?dopt=Abstract

4. Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, Roberge M, Nygaard HB. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21. doi: 10.1186/s13024-020-00369-5. PubMed PMID: 32178712; PubMed Central PMCID: PMC7075020. https://www.ncbi.nlm.nih.gov/pubmed/32178712?dopt=Abstract

5. Wunderle M, Ruebner M, Häberle L, Schwenke E, Hack CC, Bayer CM, Koch MC, Schwitulla J, Schulz-Wendtland R, Kozieradzki I, Lux MP, Beckmann MW, Jud SM, Penninger JM, Schneider MO, Fasching PA. RANKL and OPG and their influence on breast volume changes during pregnancy in healthy women. Sci Rep. 2020 Mar 20;10(1):5171. doi: 10.1038/s41598-020-62070-3. PubMed PMID: 32198488. https://www.ncbi.nlm.nih.gov/pubmed/32198488?dopt=Abstract

Mar 16, Pubcrawler Hits:

1. Sin WC, Tam N, Moniz D, Lee C, Church J. Na/H exchanger NHE1 acts upstream of rho GTPases to promote neurite outgrowth. J Cell Commun Signal. 2020 Mar 6. doi: 10.1007/s12079-020-00556-5. [Epub ahead of print] PubMed PMID: 32144636. https://www.ncbi.nlm.nih.gov/pubmed/32144636?dopt=Abstract

2. Roberts ME, Barvalia M, Silva JA, Cederberg RA, Chu W, Wong A, Tai D, Chen S, Matos I, Priatel J, Cullis PR, Harder K. Deep Phenotyping by Mass Cytometry and Single Cell RNA-Sequencing Reveals LYN Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan. Circ Res. 2020 Mar 10. doi: 10.1161/CIRCRESAHA.119.315708. [Epub ahead of print] PubMed PMID: 32151196. https://www.ncbi.nlm.nih.gov/pubmed/32151196?dopt=Abstract

3. Poole AT, Sitko CA, Le C, Naus CC, Hill BM, Bushnell EAC, Chen VC. Examination of sulfonamide-based inhibitors of MMP3 using the conditioned media of invasive glioma cells. J Enzyme Inhib Med Chem. 2020 Dec;35(1):672-681. doi: 10.1080/14756366.2020.1715387. PubMed PMID: 32156166. https://www.ncbi.nlm.nih.gov/pubmed/32156166?dopt=Abstract

4. Stringer RN, Jurkovicova-Tarabova B, Huang S, Haji-Ghassemi O, Idoux R, Liashenko A, Souza IA, Rzhepetskyy Y, Lacinova L, Van Petegem F, Zamponi GW, Pamphlett R, Weiss N. A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Ca(v)3.2 T-type channel activity. Mol Brain. 2020 Mar 6;13(1):33. doi: 10.1186/s13041-020-00577-6. PubMed PMID: 32143681; PubMed Central PMCID: PMC7060640. https://www.ncbi.nlm.nih.gov/pubmed/32143681?dopt=Abstract

5. Bravo-Caparrós I, Ruiz-Cantero MC, Perazzoli G, Cronin SJF, Vela JM, Hamed MF, Penninger JM, Baeyens JM, Cobos EJ, Nieto FR. Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury. FASEB J. 2020 Mar 10. doi: 10.1096/fj.201901921R. [Epub ahead of print] PubMed PMID: 32157739. https://www.ncbi.nlm.nih.gov/pubmed/32157739?dopt=Abstract

6. Inoue M, Hada K, Shiraishi H, Yatsuka H, Fujinami H, Morisaki I, Nishida Y, Matsubara E, Ishitani T, Hanada R, Matsumoto M, Penninger JM, Ihara K, Hanada T. Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2. Biochem Biophys Res Commun. 2020 Mar 3. pii: S0006-291X(20)30448-4. doi: 10.1016/j.bbrc.2020.02.157. [Epub ahead of print] PubMed PMID: 32143824. https://www.ncbi.nlm.nih.gov/pubmed/32143824?dopt=Abstract

Mar 9, Pubcrawler Hits:

1. Gadbery JE, Round JW, Yuan T, Wipperman MF, Story KT, Crowe AM, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS. IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria. Biochemistry. 2020 Mar 4. doi: 10.1021/acs.biochem.0c00005. [Epub ahead of print] PubMed PMID: 32101684. https://www.ncbi.nlm.nih.gov/pubmed/32101684?dopt=Abstract

2. Freitas-Andrade M, Bechberger J, Wang J, Yeung KKC, Whitehead SN, Hansen RS, Naus CC. Danegaptide Enhances Astrocyte Gap Junctional Coupling and Reduces Ischemic Reperfusion Brain Injury in Mice. Biomolecules. 2020 Feb 26;10(3). pii: E353. doi: 10.3390/biom10030353. PubMed PMID: 32110860. https://www.ncbi.nlm.nih.gov/pubmed/32110860?dopt=Abstract

3. Minina EA, Staal J, Alvarez VE, Berges JA, Berman-Frank I, Beyaert R, Bidle KD, Bornancin F, Casanova M, Cazzulo JJ, Choi CJ, Coll NS, Dixit VM, Dolinar M, Fasel N, Funk C, Gallois P, Gevaert K, Gutierrez-Beltran E, Hailfinger S, Klemenčič M, Koonin EV, Krappmann D, Linusson A, Machado MFM, Madeo F, Megeney LA, Moschou PN, Mottram JC, Nyström T, Osiewacz HD, Overall CM, Pandey KC, Ruland J, Salvesen GS, Shi Y, Smertenko A, Stael S, Ståhlberg J, Suárez MF, Thome M, Tuominen H, Van Breusegem F, van der Hoorn RAL, Vardi A, Zhivotovsky B, Lam E, Bozhkov PV. Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases. Mol Cell. 2020 Mar 5;77(5):927-929. doi: 10.1016/j.molcel.2019.12.020. PubMed PMID: 32142688. https://www.ncbi.nlm.nih.gov/pubmed/32142688?dopt=Abstract

4. Sahile HA, Rens C, Shapira T, Andersen RJ, Av-Gay Y. DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular Mycobacteria. ACS Omega. 2020 Feb 14;5(7):3661-3669. doi: 10.1021/acsomega.9b04173. eCollection 2020 Feb 25. PubMed PMID: 32118181; PubMed Central PMCID: PMC7045496. https://www.ncbi.nlm.nih.gov/pubmed/32118181?dopt=Abstract

5. Zhang H, Penninger JM, Li Y, Zhong N, Slutsky AS. Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive Care Med. 2020 Mar 3. doi: 10.1007/s00134-020-05985-9. [Epub ahead of print] PubMed PMID: 32125455. https://www.ncbi.nlm.nih.gov/pubmed/32125455?dopt=Abstract

Mar 2, Pubcrawler Hits:

1. Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, Viganò E, Gold M, Molday LL, Molday RS, Telenius A, Li MY, Wretham N, Dos Santos N, Wong M, Viller NN, Uger RA, Duns G, Baticados A, Madero A, Bristow BN, Farinha P, Slack GW, Ben-Neriah S, Lai D, Zhang AW, Salehi S, Shulha HP, Chiu DS, Mostafavi S, Gerrie AS, Huang DW, Rushton C, Villa D, Sehn LH, Savage KJ, Mungall AJ, Weng AP, Bally MB, Morin RD, Cohen Freue GV, Staudt LM, Connors JM, Marra MA, Shah SP, Gascoyne RD, Scott DW, Steidl C. TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nat Med. 2020 Feb 24. doi: 10.1038/s41591-020-0757-z. [Epub ahead of print] PubMed PMID: 32094924. https://www.ncbi.nlm.nih.gov/pubmed/32094924?dopt=Abstract

2. Dong Y, Arif AA, Guo J, Ha Z, Lee-Sayer SSM, Poon GFT, Dosanjh M, Roskelley CD, Huan T, Johnson P. CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation. Front Immunol. 2020 Jan 30;11:29. doi: 10.3389/fimmu.2020.00029. eCollection 2020. PubMed PMID: 32082314; PubMed Central PMCID: PMC7002364. https://www.ncbi.nlm.nih.gov/pubmed/32082314?dopt=Abstract

3. Hu CK, Wang W, Brind'Amour J, Singh PP, Reeves GA, Lorincz MC, Alvarado AS, Brunet A. Vertebrate diapause preserves organisms long term through Polycomb complex members. Science. 2020 Feb 21;367(6480):870-874. doi: 10.1126/science.aaw2601. PubMed PMID: 32079766. https://www.ncbi.nlm.nih.gov/pubmed/32079766?dopt=Abstract

4. Minato T, Nirasawa S, Sato T, Yamaguchi T, Hoshizaki M, Inagaki T, Nakahara K, Yoshihashi T, Ozawa R, Yokota S, Natsui M, Koyota S, Yoshiya T, Yoshizawa-Kumagaye K, Motoyama S, Gotoh T, Nakaoka Y, Penninger JM, Watanabe H, Imai Y, Takahashi S, Kuba K. B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction. Nat Commun. 2020 Feb 26;11(1):1058. doi: 10.1038/s41467-020-14867-z. PubMed PMID: 32103002. https://www.ncbi.nlm.nih.gov/pubmed/32103002?dopt=Abstract

5. Fujinami H, Shiraishi H, Hada K, Inoue M, Morisaki I, Higa R, Shin T, Kobayashi T, Hanada R, Penninger JM, Mimata H, Hanada T. CLP1 acts as the main RNA kinase in mice. Biochem Biophys Res Commun. 2020 Feb 17. pii: S0006-291X(20)30334-X. doi: 10.1016/j.bbrc.2020.02.066. [Epub ahead of print] PubMed PMID: 32081435. https://www.ncbi.nlm.nih.gov/pubmed/32081435?dopt=Abstract

Feb 24, Pubcrawler Hits:

1. Anwar MA, Barrera-Machuca AA, Calderon N, Wang W, Tausan D, Vayali T, Wishart D, Cullis P, Fraser R. Value-based healthcare delivery through metabolomics-based personalized health platform. Healthc Manage Forum. 2020 Feb 20:840470420904733. doi: 10.1177/0840470420904733. [Epub ahead of print] PubMed PMID: 32077764. https://www.ncbi.nlm.nih.gov/pubmed/32077764?dopt=Abstract

2. Alhasan MM, Cait AM, Heimesaat MM, Blaut M, Klopfleisch R, Wedel A, Conlon TM, Yildirim AÖ, Sodemann EB, Mohn WW, Bereswill S, Conrad ML. Antibiotic use during pregnancy increases offspring asthma severity in a dose dependent manner. Allergy. 2020 Feb 16. doi: 10.1111/all.14234. [Epub ahead of print] PubMed PMID: 32064643. https://www.ncbi.nlm.nih.gov/pubmed/32064643?dopt=Abstract

Feb 17, Pubcrawler Hits:

1. Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, Ostenson CG, Kieffer TJ, Banks K, Pessin JE, Gaisano HY. SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes. JCI Insight. 2020 Feb 13;5(3). pii: 129694. doi: 10.1172/jci.insight.129694. PubMed PMID: 32051343. https://www.ncbi.nlm.nih.gov/pubmed/32051343

2. Price HR, Chehroudi C, Knight SJ, Smith AD, Lai D, Kim H, Wright TE, Coughtrie MW, Collier AC. Umbilical cord as an analytical matrix - A technical note. Placenta. 2020 Jan 15;90:42-44. doi: 10.1016/j.placenta.2019.12.001. Epub 2019 Dec 3. PubMed PMID: 32056550. https://www.ncbi.nlm.nih.gov/pubmed/32056550?dopt=Abstract

Feb 10, Pubcrawler Hits:

1. Panwar P, Hedtke T, Heinz A, Andrault PM, Hoehenwarter W, Granville DJ, Schmelzer CEH, Brömme D. Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation. Biochim Biophys Acta Gen Subj. 2020 Jan 30:129544. doi: 10.1016/j.bbagen.2020.129544. [Epub ahead of print] PubMed PMID: 32007579. https://www.ncbi.nlm.nih.gov/pubmed/32007579

2. Elisia I, Lam V, Cho B, Hay M, Li MY, Kapeluto J, Elliott T, Harris D, Bu L, Jia W, Leung H, Mohn W, Krystal G. Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk. PLoS One. 2020 Feb 6;15(2):e0228633. doi: 10.1371/journal.pone.0228633. eCollection 2020. PubMed PMID: 32027700. https://www.ncbi.nlm.nih.gov/pubmed/32027700?dopt=Abstract

3. Wang K, Brohus M, Holt C, Overgaard MT, Wimmer R, Van Petegem F. Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca(2+) binding and cause misfolding. J Physiol. 2020 Feb 3. doi: 10.1113/JP279307. [Epub ahead of print] PubMed PMID: 32012279. https://www.ncbi.nlm.nih.gov/pubmed/32012279?dopt=Abstract

4. Beveridge R, Stadlmann J, Penninger JM, Mechtler K. A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes. Nat Commun. 2020 Feb 6;11(1):742. doi: 10.1038/s41467-020-14608-2. PubMed PMID: 32029734. https://www.ncbi.nlm.nih.gov/pubmed/32029734?dopt=Abstract

Feb 3, Pubcrawler Hits:

1. Tung M, Van Petegem F, Lauson S, Collier A, Hodgkinson K, Fernandez B, Connors S, Leather R, Sanatani S, Arbour L. Cardiac arrest in a mother and daughter and the identification of a novel RYR2 variant, predisposing to low penetrant catecholaminergic polymorphic ventricular tachycardia in a four-generation Canadian family. Mol Genet Genomic Med. 2020 Jan 28:e1151. doi: 10.1002/mgg3.1151. [Epub ahead of print] PubMed PMID: 31994352. https://www.ncbi.nlm.nih.gov/pubmed/31994352?dopt=Abstract

2. Gardill B, Huang J, Tu L, Van Petegem F, Oxenoid K, Thomson CA. Nanodisc technology facilitates identification of monoclonal antibodies targeting multi-pass membrane proteins. Sci Rep. 2020 Jan 24;10(1):1130. doi: 10.1038/s41598-020-58002-w. PubMed PMID: 31980674; PubMed Central PMCID: PMC6981118. https://www.ncbi.nlm.nih.gov/pubmed/31980674?dopt=Abstract

3. Bodnar TS, Raineki C, Wertelecki W, Yevtushok L, Plotka L, Granovska I, Zymak-Zakutnya N, Pashtepa A, Wells A, Honerkamp-Smith G, Coles CD, Kable JA, Chambers CD, Weinberg J; and the CIFASD. Immune network dysregulation associated with child neurodevelopmental delay: modulatory role of prenatal alcohol exposure. J Neuroinflammation. 2020 Jan 28;17(1):39. doi: 10.1186/s12974-020-1717-8. PubMed PMID: 31992316. https://www.ncbi.nlm.nih.gov/pubmed/31992316?dopt=Abstract

4. Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin SJF, Sun Y, Zhang Y, Xie C, Rodriguez J, Zhou K, Hagberg H, Mallard C, Wang X, Penninger JM, Kroemer G, Blomgren K, Zhu C. Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell Death Dis. 2020 Jan 30;11(1):77. doi: 10.1038/s41419-020-2280-z. PubMed PMID: 32001673; PubMed Central PMCID: PMC6992638. https://www.ncbi.nlm.nih.gov/pubmed/32001673?dopt=Abstract

Jan 27, Pubcrawler Hits:

1. Pourrier M, Fedida D. The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases. Int J Mol Sci. 2020 Jan 19;21(2). pii: E657. doi: 10.3390/ijms21020657. Review. PubMed PMID: 31963859. https://www.ncbi.nlm.nih.gov/pubmed/31963859?dopt=Abstract

2. Pournia F, Dang-Lawson M, Choi K, Mo V, Lampe PD, Matsuuchi L. Identification of serine residues in the Connexin43 carboxyl tail important for BCR-mediated spreading of B-lymphocytes. J Cell Sci. 2020 Jan 21. pii: jcs.237925. doi: 10.1242/jcs.237925. [Epub ahead of print] PubMed PMID: 31964709. https://www.ncbi.nlm.nih.gov/pubmed/31964709?dopt=Abstract

3. Charabati M, Donkers SJ, Kirkland MC, Osborne LC. A critical analysis of helminth immunotherapy in multiple sclerosis. Mult Scler. 2020 Jan 23:1352458519899040. doi: 10.1177/1352458519899040. [Epub ahead of print] PubMed PMID: 31971074. https://www.ncbi.nlm.nih.gov/pubmed/31971074?dopt=Abstract

4. Wat LW, Chao C, Bartlett R, Buchanan JL, Millington JW, Chih HJ, Chowdhury ZS, Biswas P, Huang V, Shin LJ, Wang LC, Gauthier ML, Barone MC, Montooth KL, Welte MA, Rideout EJ. A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown. PLoS Biol. 2020 Jan 21;18(1):e3000595. doi: 10.1371/journal.pbio.3000595. [Epub ahead of print] PubMed PMID: 31961851. https://www.ncbi.nlm.nih.gov/pubmed/31961851?dopt=Abstract

5. Li FKK, Rosell FI, Gale RT, Simorre JP, Brown ED, Strynadka NCJ. Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase. J Biol Chem. 2020 Jan 22. pii: jbc.RA119.011469. doi: 10.1074/jbc.RA119.011469. [Epub ahead of print] PubMed PMID: 31969390. https://www.ncbi.nlm.nih.gov/pubmed/31969390?dopt=Abstract

6. Gil KN, Lillie MA, Vogl AW, Shadwick RE. Rorqual whale nasal plugs: protecting the respiratory tract against water entry and barotrauma. J Exp Biol. 2020 Jan 23. pii: jeb.219691. doi: 10.1242/jeb.219691. [Epub ahead of print] PubMed PMID: 31974219. https://www.ncbi.nlm.nih.gov/pubmed/31974219?dopt=Abstract

7. Dhanda AS, Yu C, Lulic KT, Vogl AW, Rausch V, Yang D, Nichols BJ, Kim SH, Polo S, Hansen CG, Guttman JA. Listeria monocytogenes Exploits Host Caveolin for Cell-to-Cell Spreading. mBio. 2020 Jan 21;11(1). pii: e02857-19. doi: 10.1128/mBio.02857-19. PubMed PMID: 31964732. https://www.ncbi.nlm.nih.gov/pubmed/31964732?dopt=Abstract

Jan 20, Pubcrawler Hits:

1. Sheikh A, Abraham N. Interleukin-7 Receptor Alpha in Innate Lymphoid Cells: More Than a Marker. Front Immunol. 2019 Dec 11;10:2897. doi: 10.3389/fimmu.2019.02897. eCollection 2019. Review. PubMed PMID: 31921158; PubMed Central PMCID: PMC6917604. https://www.ncbi.nlm.nih.gov/pubmed/31921158?dopt=Abstract

2. Shin JJH, Liu P, Chan LJ, Ullah A, Pan J, Borchers CH, Burke JE, Stefan C, Smits GJ, Loewen CJR. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. Dev Cell. 2020 Jan 9. pii: S1534-5807(19)31031-7. doi: 10.1016/j.devcel.2019.12.010. [Epub ahead of print] PubMed PMID: 31928972. https://www.ncbi.nlm.nih.gov/pubmed/31928972?dopt=Abstract

3. Findlay Black H, Mastromatteo S, Sinha S, Ehrlich RL, Nislow C, Chang Mell J, Redfield RJ. A competence-regulated toxin-antitoxin system in Haemophilus influenzae. PLoS One. 2020 Jan 13;15(1):e0217255. doi: 10.1371/journal.pone.0217255. eCollection 2020. PubMed PMID: 31931516. https://www.ncbi.nlm.nih.gov/pubmed/31931516?dopt=Abstract

Jan 13, Pubcrawler Hits:

1. Asghari P, Scriven DR, Ng M, Panwar P, Chou KC, van Petegem F, Moore ED. Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification. Elife. 2020 Jan 9;9. pii: e51602. doi: 10.7554/eLife.51602. [Epub ahead of print] PubMed PMID: 31916935. https://www.ncbi.nlm.nih.gov/pubmed/31916935?dopt=Abstract

2. Indira Chandran V, Mansson AS, Barbachowska M, Cerezo-Magana M, Nodin B, Joshi B, Koppada N, Saad OM, Gluz O, Isaksson K, Borgquist S, Jirstrom K, Nabi IR, Jernstrom H, Belting M. Hypoxia attenuates trastuzumab uptake and trastuzumab-emtansine (T-DM1) cytotoxicity through redistribution of phosphorylated caveolin-1. Mol Cancer Res. 2020 Jan 3. pii: molcanres.0856.2019. doi: 10.1158/1541-7786.MCR-19-0856. [Epub ahead of print] PubMed PMID: 31900313. https://www.ncbi.nlm.nih.gov/pubmed/31900313?dopt=Abstract

Jan 6, Pubcrawler Hits:

1. Durrer C, McKelvey S, Singer J, Batterham AM, Johnson JD, Wortman J, Little JP. Pharmacist-led therapeutic carbohydrate restriction as a treatment strategy for type 2 diabetes: the Pharm-TCR randomized controlled trial protocol. Trials. 2019 Dec 27;20(1):781. doi: 10.1186/s13063-019-3873-7. PubMed PMID: 31881991; PubMed Central PMCID: PMC6935079. https://www.ncbi.nlm.nih.gov/pubmed/31881991?dopt=Abstract

2. Jaraíz-Rodríguez M, Talaverón R, García-Vicente L, Pelaz SG, Domínguez-Prieto M, Álvarez-Vázquez A, Flores-Hernández R, Sin WC, Bechberger J, Medina JM, Naus CC, Tabernero A. Connexin43 peptide, TAT-Cx43266-283, selectively targets glioma cells, impairs malignant growth and enhances survival in mouse models in vivo. Neuro Oncol. 2019 Dec 28. pii: noz243. doi: 10.1093/neuonc/noz243. [Epub ahead of print] PubMed PMID: 31883012. https://www.ncbi.nlm.nih.gov/pubmed/31883012?dopt=Abstract

Dec 23, Pubcrawler Hits:

1. Nappi L, Aguda AH, Nakouzi NA, Lelj-Garolla B, Beraldi E, Lallous N, Thi M, Moore S, Fazli L, Battsogt D, Stoffeliene S, Ban F, Nguyen NT, Saxena N, Dueva E, Zhang F, Yamazaki T, Zoubeidi A, Cherkasov A, Brayer GD, Gleave M. Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models. J Clin Invest. 2019 Dec 17. pii: 130819. doi: 10.1172/JCI130819. [Epub ahead of print] PubMed PMID: 31845908. https://www.ncbi.nlm.nih.gov/pubmed/31845908?dopt=Abstract

2. Andrault PM, Panwar P, Brömme D. Characterization of Cathepsin S exosites that govern its elastolytic activity. Biochem J. 2019 Dec 20. pii: BCJ20190847. doi: 10.1042/BCJ20190847. [Epub ahead of print] PubMed PMID: 31860022. https://www.ncbi.nlm.nih.gov/pubmed/31860022?dopt=Abstract

3. Round P, Das S, Wu TS, Wähälä K, Van Petegem F, Hammond GL. Molecular interactions between sex hormone-binding globulin and non-steroidal ligands that enhance androgen action. J Biol Chem. 2019 Dec 18. pii: jbc.RA119.011051. doi: 10.1074/jbc.RA119.011051. [Epub ahead of print] PubMed PMID: 31852737. https://www.ncbi.nlm.nih.gov/pubmed/31852737?dopt=Abstract

4. Herrmann J, Li PN, Jabbarpour F, Chan ACK, Rajkovic I, Matsui T, Shapiro L, Smit J, Weiss TM, Murphy MEP, Wakatsuki S. A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proc Natl Acad Sci U S A. 2019 Dec 17. pii: 201909798. doi: 10.1073/pnas.1909798116. [Epub ahead of print] PubMed PMID: 31848245. https://www.ncbi.nlm.nih.gov/pubmed/31848245?dopt=Abstract

5. Hsu CR, Xiong R, Sugioka K. In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads. J Vis Exp. 2019 Nov 26;(153). doi: 10.3791/60422. PubMed PMID: 31840666. https://www.ncbi.nlm.nih.gov/pubmed/31840666?dopt=Abstract

Dec 16, Pubcrawler Hits:

1. Bogutz AB, Brind'Amour J, Kobayashi H, Jensen KN, Nakabayashi K, Imai H, Lorincz MC, Lefebvre L. Evolution of imprinting via lineage-specific insertion of retroviral promoters. Nat Commun. 2019 Dec 12;10(1):5674. doi: 10.1038/s41467-019-13662-9. PubMed PMID: 31831741. https://www.ncbi.nlm.nih.gov/pubmed/31831741?dopt=Abstract

2. Hu J, Worrall LJ, Strynadka NC. Towards capture of dynamic assembly and action of the T3SS at near atomic resolution. Curr Opin Struct Biol. 2019 Dec 7;61:71-78. doi: 10.1016/j.sbi.2019.10.005. [Epub ahead of print] Review. PubMed PMID: 31821956. https://www.ncbi.nlm.nih.gov/pubmed/31821956?dopt=Abstract

Dec 9, Pubcrawler Hits:

1. Thompson KJ, Kenward PA, Bauer KW, Warchola T, Gauger T, Martinez R, Simister RL, Michiels CC, Llirós M, Reinhard CT, Kappler A, Konhauser KO, Crowe SA. Photoferrotrophy, deposition of banded iron formations, and methane production in Archean oceans. Sci Adv. 2019 Nov 27;5(11):eaav2869. doi: 10.1126/sciadv.aav2869. eCollection 2019 Nov. PubMed PMID: 31807693; PubMed Central PMCID: PMC6881150. https://www.ncbi.nlm.nih.gov/pubmed/31807693?dopt=Abstract

2. Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, Kulkarni JA, van der Meel R, Cullis PR. The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs. Nat Nanotechnol. 2019 Dec;14(12):1084-1087. doi: 10.1038/s41565-019-0591-y. PubMed PMID: 31802031. https://www.ncbi.nlm.nih.gov/pubmed/31802031?dopt=Abstract

3. Yazer MH, Spinella PC, Doyle L, Kaufman RM, Dunn R, Hess JR, Filho LA, Fontaine M, Gathof B, Jackson B, Murphy MF, Pasion J, Raval JS, Rosinski K, Seheult J, Shih AW, Sperry J, Staves J, Tuott EE, Ziman A, Triulzi DJ, McKenna D, Stroncek D, Fung M, Tinmouth A, Devine D, Cardigan R, Vassallo R, Germain M, Reems J, Garritsen H, Takanashi M, Stanworth S, Delaney M, Cancelas J, Meer PV, Marks D, Cohn C, Shaz B, Tiberghien P, Goldman M, Girdlestone J, Pati S, Schäfer R, Schwartz JY, Dunbar N, Pagano M, So-Osman C, Noorman F, Apelseth TO, Kanias T, Stolla M, Angelantonio ED, Hurk KVD, Steele WR, Erikstrup C, Merz EM; Biomedical Excellence for Safer Transfusion Collaborative; Appendix. Members of the Biomedical Excellence for Safer Transfusion Collaborative. Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere with Most ABO Typings. Anesthesiology. 2019 Nov 25. doi: 10.1097/ALN.0000000000003069. [Epub ahead of print] PubMed PMID: 31789634. https://www.ncbi.nlm.nih.gov/pubmed/31789634?dopt=Abstract

4. Lu M, Mizumoto K. Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans. Elife. 2019 Dec 5;8. pii: e50583. doi: 10.7554/eLife.50583. PubMed PMID: 31804181; PubMed Central PMCID: PMC6894928. https://www.ncbi.nlm.nih.gov/pubmed/31804181?dopt=Abstract

5. Paik YK, Overall CM, Corrales F, Deutsch EW, Lane L, Omenn GS. Advances in Identifying and Characterizing the Human Proteome. J Proteome Res. 2019 Dec 6;18(12):4079-4084. doi: 10.1021/acs.jproteome.9b00745. PubMed PMID: 31805768. https://www.ncbi.nlm.nih.gov/pubmed/31805768?dopt=Abstract

6. Fallata AM, Wyatt RA, Levesque JM, Dufour A, Overall CM, Crawford BD. Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance. Biomedicines. 2019 Nov 29;7(4). pii: E93. doi: 10.3390/biomedicines7040093. PubMed PMID: 31795436. https://www.ncbi.nlm.nih.gov/pubmed/31795436?dopt=Abstract

7. Van Petegem F, Gardill BR. Reply to Pitt and Lee: Occupancies of Ca(2+) in complexes of calmodulin with voltage-gated sodium channels. Proc Natl Acad Sci U S A. 2019 Dec 3. pii: 201918159. doi: 10.1073/pnas.1918159116. [Epub ahead of print] PubMed PMID: 31796598. https://www.ncbi.nlm.nih.gov/pubmed/31796598?dopt=Abstract

8. Islamzada E, Matthews K, Guo Q, Santoso AT, Duffy SP, Scott MD, Ma H. Deformability based sorting of stored red blood cells reveals donor-dependent aging curves. Lab Chip. 2019 Dec 4. doi: 10.1039/c9lc01058k. [Epub ahead of print] PubMed PMID: 31796943. https://www.ncbi.nlm.nih.gov/pubmed/31796943?dopt=Abstract

Dec 2, Pubcrawler Hits:

1. Bray MS, Wu J, Padilla CC, Stewart FJ, Fowle DA, Henny C, Simister RL, Thompson KJ, Crowe SA, Glass JB. Phylogenetic and structural diversity of aromatically dense pili from environmental metagenomes. Environ Microbiol Rep. 2019 Nov 7. doi: 10.1111/1758-2229.12809. [Epub ahead of print] PubMed PMID: 31701641. https://www.ncbi.nlm.nih.gov/pubmed/31701641?dopt=Abstract

2. McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH. Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation. Proc Natl Acad Sci U S A. 2019 Nov 21. pii: 201912049. doi: 10.1073/pnas.1912049116. [Epub ahead of print] PubMed PMID: 31754030. https://www.ncbi.nlm.nih.gov/pubmed/31754030?dopt=Abstract

3. Jobin PG, Solis N, Machado Y, Bell PA, Rai SK, Kwon NH, Kim S, Overall CM, Butler GS. Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. J Biol Chem. 2019 Nov 26. pii: jbc.RA119.010486. doi: 10.1074/jbc.RA119.010486. [Epub ahead of print] PubMed PMID: 31771979. https://www.ncbi.nlm.nih.gov/pubmed/31771979?dopt=Abstract

Nov 25, Pubcrawler Hits:

1. Shimell JJ, Shah BS, Cain SM, Thouta S, Kuhlmann N, Tatarnikov I, Jovellar DB, Brigidi GS, Kass J, Milnerwood AJ, Snutch TP, Bamji SX. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation. Cell Rep. 2019 Nov 19;29(8):2422-2437.e8. doi: 10.1016/j.celrep.2019.10.065. PubMed PMID: 31747610. https://www.ncbi.nlm.nih.gov/pubmed/31747610?dopt=Abstract

2. Fenninger F, Han J, Stanwood SR, Nohara LL, Arora H, Choi KB, Munro L, Pfeifer CG, Shanina I, Horwitz MS, Jefferies WA. Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction. Front Immunol. 2019 Oct 29;10:2473. doi: 10.3389/fimmu.2019.02473. eCollection 2019. PubMed PMID: 31736943; PubMed Central PMCID: PMC6833481. https://www.ncbi.nlm.nih.gov/pubmed/31736943?dopt=Abstract

3. Cronin SJF, Woolf CJ, Weiss G, Penninger JM. The Role of Iron Regulation in Immunometabolism and Immune-Related Disease. Front Mol Biosci. 2019 Nov 22;6:116. doi: 10.3389/fmolb.2019.00116. eCollection 2019. Review. PubMed PMID: 31824960; PubMed Central PMCID: PMC6883604. https://www.ncbi.nlm.nih.gov/pubmed/31824960

Nov 18, Pubcrawler Hits:

1. Li L, Chen B, Zhu R, Li R, Tian Y, Liu C, Jia Q, Wang L, Tang J, Zhao D, Mo F, Liu Y, Li Y, Orekhov AN, Brömme D, Zhang D, Gao S. Fructus Ligustri Lucidi preserves bone quality through the regulation of gut microbiota diversity, oxidative stress, TMAO and Sirt6 levels in aging mice. Aging (Albany NY). 2019 Nov 12;11. doi: 10.18632/aging.102376. [Epub ahead of print] PubMed PMID: 31715585. https://www.ncbi.nlm.nih.gov/pubmed/31715585?dopt=Abstract

2. Kulkarni JA, Witzigmann D, Leung J, Tam YYC, Cullis PR. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 12. doi: 10.1039/c9nr09347h. [Epub ahead of print] PubMed PMID: 31713568. https://www.ncbi.nlm.nih.gov/pubmed/31713568?dopt=Abstract

3. Holert J, Brown K, Hashimi A, Eltis LD, Mohn WW. Steryl ester formation and accumulation in steroid-degrading bacteria. Appl Environ Microbiol. 2019 Nov 8. pii: AEM.02353-19. doi: 10.1128/AEM.02353-19. [Epub ahead of print] PubMed PMID: 31704679. https://www.ncbi.nlm.nih.gov/pubmed/31704679?dopt=Abstract

4. Wang Y, Eldstrom J, Fedida D. The IKs ion channel activator, mefenamic acid, requires KCNE1 and modulates channel gating in a subunit-dependent manner. Mol Pharmacol. 2019 Nov 13. pii: mol.119.117952. doi: 10.1124/mol.119.117952. [Epub ahead of print] PubMed PMID: 31722973. https://www.ncbi.nlm.nih.gov/pubmed/31722973?dopt=Abstract

5. Novales Flamarique I, Sayed Ahmed A, Cheng CL, Molday RS, Devlin RH. Growth hormone regulates opsin expression in the retina of a salmonid fish. J Neuroendocrinol. 2019 Oct 20:e12804. doi: 10.1111/jne.12804. [Epub ahead of print] PubMed PMID: 31630448. https://www.ncbi.nlm.nih.gov/pubmed/31630448?dopt=Abstract

Nov 11, Pubcrawler Hits:

1. Posynick BJ, Brown CJ. Escape From X-Chromosome Inactivation: An Evolutionary Perspective. Front Cell Dev Biol. 2019 Oct 22;7:241. doi: 10.3389/fcell.2019.00241. eCollection 2019. Review. PubMed PMID: 31696116; PubMed Central PMCID: PMC6817483. https://www.ncbi.nlm.nih.gov/pubmed/31696116?dopt=Abstract

2. Urtatiz O, Cook C, Huang JL, Yeh I, Van Raamsdonk CD. GNAQ(Q209L) expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. Pigment Cell Melanoma Res. 2019 Nov 4. doi: 10.1111/pcmr.12843. [Epub ahead of print] PubMed PMID: 31680437. https://www.ncbi.nlm.nih.gov/pubmed/31680437?dopt=Abstract

3. Ding H, Grüll MP, Mulligan ME, Lang AS, Beatty JT. Induction of Rhodobacter capsulatus Gene Transfer Agent Gene Expression Is a Bistable Stochastic Process Repressed by an Extracellular Calcium-Binding RTX Protein Homologue. J Bacteriol. 2019 Nov 5;201(23):e00430-19. doi: 10.1128/JB.00430-19. PMID: 31501287; PMCID: PMC6832060. https://pubmed.ncbi.nlm.nih.gov/31501287/

Nov 4, Pubcrawler Hits:

1. Stadlmann J, Hudecz O, Krššáková G, Ctortecka C, Van Raemdonck G, Op De Beeck J, Desmet G, Penninger JM, Jacobs P, Mechtler K. Improved Sensitivity in Low-Input Proteomics Using Micropillar Array-Based Chromatography. Anal Chem. 2019 Oct 31. doi: 10.1021/acs.analchem.9b02899. [Epub ahead of print] PubMed PMID: 31612716. https://www.ncbi.nlm.nih.gov/pubmed/31612716?dopt=Abstract

Oct 28, Pubcrawler Hits:

1. Deutsch EW, Lane L, Overall CM, Bandeira N, Baker MS, Pineau C, Moritz RL, Corrales F, Orchard S, Van Eyk JE, Paik YK, Weintraub ST, Vandenbrouck Y, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0.  J Proteome Res. 2019 Oct 21. doi: 10.1021/acs.jproteome.9b00542. [Epub ahead of print] PubMed PMID: 31599596. https://www.ncbi.nlm.nih.gov/pubmed/31599596?dopt=Abstract

2. Richter A, Shapira T, Av-Gay Y. THP-1 and Dictyostelium infection models for screening and characterization of anti-Mycobacterium abscessus hit compounds. Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01601-19. doi: 10.1128/AAC.01601-19. [Epub ahead of print] PubMed PMID: 31636068. https://www.ncbi.nlm.nih.gov/pubmed/31636068?dopt=Abstract

Oct 21, Pubcrawler Hits:

1. Vardaki M, Devine D, Serrano K, Simantiris N, Blades M, Piret JM, Turner R. Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy (SORS) Device. Appl Spectrosc. 2019 Oct 16:3702819884625. doi: 10.1177/0003702819884625. [Epub ahead of print] PubMed PMID: 31617382. https://www.ncbi.nlm.nih.gov/pubmed/31617382?dopt=Abstract

2. Solis N, Parambath A, Abbina S, Kizhakkedathu J, Overall CM. Simplified high yield TAILS terminomics using a new HPG-ALD 800K-2000 polymer with precipitation. Methods Enzymol. 2019; 626:429-446. doi: 10.1016/bs.mie.2019.07.030. Epub 2019 Aug 13. PubMed PMID: 31606086. https://www.ncbi.nlm.nih.gov/pubmed/31606086?dopt=Abstract

3. Guissart C, Harrison AN, Benkirane M, Oncel I, Arslan EA, Chassevent AK, Baraῆano K, Larrieu L, Iascone M, Tenconi R, Claustres M, Eroglu-Ertugrul N, Calvas P, Topaloglu H, Molday RS, Koenig M. ATP8A2-related disorders as recessive cerebellar ataxia. J Neurol. 2019 Oct 14. doi: 10.1007/s00415-019-09579-4. [Epub ahead of print] PubMed PMID: 31612321. https://www.ncbi.nlm.nih.gov/pubmed/31612321?dopt=Abstract

4. Kurata T, Rajendran V, Fan S, Ohta T, Numata M, Fushida S. NHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cells. Clin Exp Metastasis. 2019 Oct 8. doi: 10.1007/s10585-019-10001-6. [Epub ahead of print] PubMed PMID: 31595389. https://www.ncbi.nlm.nih.gov/pubmed/31595389?dopt=Abstract

5. Fons JM, Gaete M, Zahradnicek O, Landova M, Bandali H, Khannoon ER, Richman JM, Buchtova M, Tucker AS. Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake. Dev Dyn. 2019 Oct 6. doi: 10.1002/dvdy.120. [Epub ahead of print] PubMed PMID: 31587402. https://www.ncbi.nlm.nih.gov/pubmed/31587402?dopt=Abstract

6. Hamada K, Omura N, Taguchi A, Baradaran-Heravi A, Kotake M, Arai M, Takayama K, Taniguchi A, Roberge M, Hayashi Y. New Negamycin-Based Potent Readthrough Derivative Effective against TGA-Type Nonsense Mutations. ACS Med Chem Lett. 2019 Sep 23; 10(10):1450-1456. doi: 10.1021/acsmedchemlett.9b00273. eCollection 2019 Oct 10. PubMed PMID: 31620232; PubMed Central PMCID: PMC6792177. https://www.ncbi.nlm.nih.gov/pubmed/31620232?dopt=Abstract

7. Taha M, Kyluik-Price D, Kumaran D, Scott MD, Toyofuku W, Ramirez-Arcos S. Bacterial survival in whole blood depends on plasma sensitivity and resistance to neutrophil killing. Transfusion. 2019 Oct 13. doi: 10.1111/trf.15550. [Epub ahead of print] PubMed PMID: 31608457. https://www.ncbi.nlm.nih.gov/pubmed/31608457?dopt=Abstract

8. Hashemi P, Sadowski I. Diversity of small molecule HIV-1 latency reversing agents identified in low- and high-throughput small molecule screens. Med Res Rev. 2020 May;40(3):881-908. doi: 10.1002/med.21638. Epub 2019 Oct 13. PMID: 31608481; PMCID: PMC7216841. https://pubmed.ncbi.nlm.nih.gov/31608481/

Sep 30, Pubcrawler Hits:

1. Kim H, Conway EM. Platelets and Complement Cross-Talk in Early Atherogenesis. Front Cardiovasc Med. 2019 Sep 6;6:131. doi: 10.3389/fcvm.2019.00131. eCollection 2019. Review. PubMed PMID: 31555668; PubMed Central PMCID: PMC6742699. https://www.ncbi.nlm.nih.gov/pubmed/31555668?dopt=Abstract

2. Wimmer RA, Leopoldi A, Aichinger M, Kerjaschki D, Penninger JM. Generation of blood vessel organoids from human pluripotent stem cells. Nat Protoc. 2019 Sep 25. doi: 10.1038/s41596-019-0213-z. [Epub ahead of print] PubMed PMID: 31554955. https://www.ncbi.nlm.nih.gov/pubmed/31554955?dopt=Abstract

Sep 23, Pubcrawler Hits:

1. Rahfeld P, Wardman JF, Mehr K, Huff D, Morgan-Lang C, Chen HM, Hallam SJ, Withers SG. Prospecting for α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase. J Biol Chem. 2019 Sep 17. pii: jbc.RA119.010628. doi: 10.1074/jbc.RA119.010628. [Epub ahead of print] PubMed PMID: 31530641. https://www.ncbi.nlm.nih.gov/pubmed/31530641?report=&dispmax=200&tool=PubCrawler_1.4

2. Chehroudi C, Kim H, Wright TE, Collier AC. Dysregulation of inflammatory cytokines and inhibition of VEGFA in the human umbilical cord are associated with negative pregnancy outcomes. Placenta. 2019 Sep 3;87:16-22. doi: 10.1016/j.placenta.2019.09.002. [Epub ahead of print] PubMed PMID: 31525711. https://www.ncbi.nlm.nih.gov/pubmed/31525711

3. Lyons BJE, Strynadka NCJ. On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome. Medchemcomm. 2019 Jun 20;10(8):1273-1289. doi: 10.1039/c9md00146h. eCollection 2019 Aug 1. Review. PubMed PMID: 31534650; PubMed Central PMCID: PMC6748289. https://www.ncbi.nlm.nih.gov/pubmed/31534650?report=&dispmax=200&tool=PubCrawler_1.4

4. Van Petegem F. Slaying a giant: Structures of calmodulin and protein kinase a bound to the cardiac ryanodine receptor. Cell Calcium. 2019 Sep 6; 83:102079. doi: 10.1016/j.ceca.2019.102079. [Epub ahead of print] PubMed PMID: 31522075. https://www.ncbi.nlm.nih.gov/pubmed/31522075?report=&dispmax=200&tool=PubCrawler_1.4

Sep 16, Pubcrawler Hits:

1. Ding H, Grüll MP, Mulligan ME, Lang AS, Beatty JT. Induction of Rhodobacter capsulatus gene transfer agent (RcGTA) gene expression is a bistable stochastic process repressed by an extracellular calcium-binding RTX protein homologue. J Bacteriol. 2019 Sep 9. pii: JB.00430-19. doi: 10.1128/JB.00430-19. [Epub ahead of print] PubMed PMID: 31501287. https://www.ncbi.nlm.nih.gov/pubmed/31501287?dopt=Abstract

2. Zhang W, Böttger R, Qin Z, Kulkarni JA, Vogler J, Cullis PR, Li SD. Phospholipid-Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver. Small. 2019 Sep 6:e1901782. doi: 10.1002/smll.201901782. [Epub ahead of print] PubMed PMID: 31490617. https://www.ncbi.nlm.nih.gov/pubmed/31490617?dopt=Abstract

Sep 09, Pubcrawler Hits:

1. Ng LCT, Zhuang M, Van Petegem F, Li YX, Accili EA. Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide-gated ion channel. J Gen Physiol. 2019 Sep 3. pii: jgp.201812162. doi: 10.1085/jgp.201812162. [Epub ahead of print] PubMed PMID: 31481514. https://www.ncbi.nlm.nih.gov/pubmed/31481514?report=&dispmax=200&tool=PubCrawler_1.4

2. Forde ON, Cahill AG, Mayer KU, Mayer B, Simister RL, Finke N, Crowe SA, Cherry JA, Parker BL. Hydro-biogeochemical impacts of fugitive methane on a shallow unconfined aquifer. Sci Total Environ. 2019 Nov 10;690:1342-1354. doi: 10.1016/j.scitotenv.2019.06.322. Epub 2019 Jun 30. PubMed PMID: 31470496. https://www.ncbi.nlm.nih.gov/pubmed/31470496?report=&dispmax=200&tool=PubCrawler_1.4

3. Levy-Booth DJ, Fetherolf MM, Stewart GR, Liu J, Eltis LD, Mohn WW. Catabolism of Alkylphenols in Rhodococcus via a Meta-Cleavage Pathway Associated With Genomic Islands. Front Microbiol. 2019 Aug 20;10:1862. doi: 10.3389/fmicb.2019.01862. eCollection 2019. PubMed PMID: 31481940; PubMed Central PMCID: PMC6710988. https://www.ncbi.nlm.nih.gov/pubmed/31481940?report=&dispmax=200&tool=PubCrawler_1.4

4. Chen KTJ, Anantha M, Leung AWY, Kulkarni JA, Militao GGC, Wehbe M, Sutherland B, Cullis PR, Bally MB. Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use. Drug Deliv Transl Res. 2019 Sep 3. doi: 10.1007/s13346-019-00674-7. [Epub ahead of print] PubMed PMID: 31482519. https://www.ncbi.nlm.nih.gov/pubmed/31482519?report=&dispmax=200&tool=PubCrawler_1.4

Sep 02, Pubcrawler Hits:

1. Sharifkhodaei Z, Gilbert MM, Auld VJ. Scribble and Discs-large mediate tricellular junction formation. Development. 2019 Aug 23. pii: dev.174763. doi: 10.1242/dev.174763. [Epub ahead of print] PubMed PMID: 31444218. https://www.ncbi.nlm.nih.gov/pubmed/31444218?dopt=Abstract

2. Noël G, Tham DKL, MacVicar BA, Moukhles H. Agrin plays a major role in the coalescence of the AQP4 clusters induced by gamma-1-containing laminin. J Comp Neurol. 2019 Aug 27. doi: 10.1002/cne.24763. [Epub ahead of print] PubMed PMID: 31454080. https://www.ncbi.nlm.nih.gov/pubmed/31454080?dopt=Abstract

3. Khater IM, Aroca-Ouellette ST, Meng F, Nabi IR, Hamarneh G. Caveolae and scaffold detection from single molecule localization microscopy data using deep learning. PLoS One. 2019 Aug 26;14(8):e0211659. doi: 10.1371/journal.pone.0211659. eCollection 2019. PubMed PMID: 31449531. https://www.ncbi.nlm.nih.gov/pubmed/31449531?dopt=Abstract

Aug 26, Pubcrawler Hits:

1. Conway EM. Thrombin: Coagulation's master regulator of innate immunity. J Thromb Haemost. 2019 Aug 20. doi: 10.1111/jth.14586. [Epub ahead of print] PubMed PMID: 31429203. https://www.ncbi.nlm.nih.gov/pubmed/31429203?dopt=Abstract

2. Gordon MH, Anowai A, Young D, Das N, Campden RI, Sekhon H, Myers Z, Mainoli B, Chopra S, Thuy-Boun PS, Kizhakkedathu J, Bindra G, Jijon HB, Heitman S, Yates R, Wolan DW, Edgington-Mitchell LE, MacNaughton WK, Dufour A. N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis. ACS Chem Biol. 2019 Aug 21. doi: 10.1021/acschembio.9b00608. [Epub ahead of print] PubMed PMID: 31393699. https://www.ncbi.nlm.nih.gov/pubmed/31393699?dopt=Abstract

3. Sadr Karimi S, Pante N. Carbon nanotubes as molecular transporters to study a new mechanism for molecular entry into the cell nucleus using actin polymerization force. PLoS One. 2019 Aug 22;14(8):e0221562. doi: 10.1371/journal.pone.0221562. eCollection 2019. PubMed PMID: 31437229. https://www.ncbi.nlm.nih.gov/pubmed/31429667?dopt=Abstract

4. Jakubovics N, Richman J. JDR Historical Highlights #10. J Dent Res. 2019 Sep;98(10):1063-1065. doi: 10.1177/0022034519864885. PubMed PMID: 31429667. https://www.ncbi.nlm.nih.gov/pubmed/31437229?dopt=Abstract

5. Hu J, Worrall LJ, Vuckovic M, Hong C, Deng W, Atkinson CE, Brett Finlay B, Yu Z, Strynadka NCJ. T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. Nat Microbiol. 2019 Aug 19. doi: 10.1038/s41564-019-0545-z. [Epub ahead of print] PubMed PMID: 31427728. https://www.ncbi.nlm.nih.gov/pubmed/31427728?dopt=Abstract

Aug 19, Pubcrawler Hits:

1. Marshall EA, Stewart GL, Sage AP, Lam WL, Brown CJ. Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge. PLoS One. 2019 Aug 16;14(8):e0221371. doi: 10.1371/journal.pone.0221371. eCollection 2019. PubMed PMID: 31419261. https://www.ncbi.nlm.nih.gov/pubmed/31419261?dopt=Abstract

2. Kulkarni JA, Witzigmann D, Chen S, Cullis PR, van der Meel R. Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics. Acc Chem Res. 2019 Aug 9. doi: 10.1021/acs.accounts.9b00368. [Epub ahead of print] PubMed PMID: 31397996. https://www.ncbi.nlm.nih.gov/pubmed/31397996?dopt=Abstract

3. Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV. Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood. Transfusion. 2019 Aug 13. doi: 10.1111/trf.15485. [Epub ahead of print] PubMed PMID: 31408208. https://www.ncbi.nlm.nih.gov/pubmed/31408208?dopt=Abstract

4. Hanson PJ, Hossain AR, Qiu Y, Zhang HM, Zhao G, Li C, Lin V, Sulaimon S, Vlok M, Fung G, Chen VH, Jan E, McManus BM, Granville DJ, Yang D. Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection. Front Cell Infect Microbiol. 2019 Jul 24;9:265. doi: 10.3389/fcimb.2019.00265. eCollection 2019. PubMed PMID: 31396490; PubMed Central PMCID: PMC6667557. https://www.ncbi.nlm.nih.gov/pubmed/31396490?dopt=Abstract

5. Shi H, Strogantsev R, Takahashi N, Kazachenka A, Lorincz MC, Hemberger M, Ferguson-Smith AC. ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains. Epigenetics Chromatin. 2019 Aug 9; 12(1):49. doi: 10.1186/s13072-019-0295-4. PubMed PMID: 31399135; PubMed Central PMCID: PMC6688207. https://www.ncbi.nlm.nih.gov/pubmed/31399135?dopt=Abstract

6. Dyka FM, Molday LL, Chiodo V, Molday RS, Hauswirth WW. Dual ABCA4-AAV vector treatment reduces pathogenic retinal A2E accumulation in a mouse model of autosomal recessive Stargardt Disease. Hum Gene Ther. 2019 Aug 16. doi: 10.1089/hum.2019.132. [Epub ahead of print] PubMed PMID: 31418294. https://www.ncbi.nlm.nih.gov/pubmed/31418294?dopt=Abstract

7. Choi H, Andersen JP, Molday RS. Expression and Functional Characterization of Missense Mutations in ATP8A2 Linked to Severe Neurological Disorders. Hum Mutat. 2019 Aug 9. doi: 10.1002/humu.23889. [Epub ahead of print] PubMed PMID: 31397519. https://www.ncbi.nlm.nih.gov/pubmed/31397519?dopt=Abstract

8. Mellor GJ, Panwar P, Lee AK, Steinberg C, Hathaway JA, Bartels K, Christian S, Balaji S, Roberts JD, Simpson CS, Boczek NJ, Tester DJ, Radbill AE, Mok NS, Hamilton RM, Kaufman ES, Eugenio PL, Weiss R, January C, McDaniel GM, Leather RA, Erickson C, Falik S, Behr ER, Wilde AAM, Sanatani S, Ackerman MJ, Van Petegem F, Krahn AD, Laksman Z. Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site. Europace. 2019 Aug pii: euz215. doi: 10.1093/europace/euz215. [Epub ahead of print] PubMed PMID: 31408100. https://www.ncbi.nlm.nih.gov/pubmed/31408100?dopt=Abstract

9. Kwan JZJ, Nguyen TF, Teves SS. Visualizing Transcription Factor Binding on Mitotic Chromosomes Using Single-Molecule Live-Cell Imaging. Methods Mol Biol. 2019; 2038:239-250. doi: 10.1007/978-1-4939-9674-2_16. PubMed PMID: 31407289. https://www.ncbi.nlm.nih.gov/pubmed/31407289?dopt=Abstract

Aug 12, Pubcrawler Hits:

1. Devine DV. Ironing out frequent blood donation. Lancet Haematol. 2019 Aug 2. pii: S2352-3026(19)30162-0. doi: 10.1016/S2352-3026(19)30162-0. [Epub ahead of print] PubMed PMID: 31383582. https://www.ncbi.nlm.nih.gov/pubmed/31383582?dopt=Abstract

2. Zhang AMY, Magrill J, de Winter TJJ, Hu X, Skovsø S, Schaeffer DF, Kopp JL, Johnson JD. Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development. Cell Metab. 2019 Jul 23. pii: S1550-4131(19)30376-6. doi: 10.1016/j.cmet.2019.07.003. [Epub ahead of print] PubMed PMID: 31378465. https://www.ncbi.nlm.nih.gov/pubmed/31378465?dopt=Abstract

3. Zelanis A, Oliveira AK, Prudova A, Huesgen PF, Tashima AK, Kizhakkedathu J, Overall CM, Serrano SMT. Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Substrates (TAILS) N-Terminomics. J Proteome Res. 2019 Aug 8. doi: 10.1021/acs.jproteome.9b00325. [Epub ahead of print] PubMed PMID: 31337208. https://www.ncbi.nlm.nih.gov/pubmed/31337208?dopt=Abstract

4. Tadini-Buoninsegni F, Mikkelsen SA, Mogensen LS, Molday RS, Andersen JP. Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic. Proc Natl Acad Sci U S A. 2019 Aug 1. pii: 201910211. doi: 10.1073/pnas.1910211116. [Epub ahead of print] PubMed PMID: 31371510. https://www.ncbi.nlm.nih.gov/pubmed/31371510?dopt=Abstract

Aug 5, Pubcrawler Hits:

1. Carlson ML, Stacey RG, Young JW, Wason IS, Zhao Z, Rattray DG, Scott N, Kerr CH, Babu M, Foster LJ, Duong FVH. Profiling the E. coli membrane interactome captured in peptidisc libraries. Elife. 2019 Jul 31;8. pii: e46615. doi: 10.7554/eLife.46615. [Epub ahead of print] PubMed PMID: 31364989. https://www.ncbi.nlm.nih.gov/pubmed/31364989?dopt=Abstract

2. Heinkel F, Abraham L, Ko M, Chao J, Bach H, Hui LT, Li H, Zhu M, Ling YM, Rogalski JC, Scurll J, Bui JM, Mayor T, Gold MR, Chou KC, Av-Gay Y, McIntosh LP, Gsponer J. Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2019 Jul 31. pii: 201820683. doi:10.1073/pnas.1820683116. [Epub ahead of print] PubMed PMID: 31366629. https://www.ncbi.nlm.nih.gov/pubmed/31366629?dopt=Abstract

3. Tudurí E, Glavas MM, Asadi A, Baker RK, Ellis CE, Soukhatcheva G, Philit M, Huynh FK, Johnson JD, Bruce Verchere C, Kieffer TJ. AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells. Sci Rep. 2019 Jul 25;9(1):10829. doi: 10.1038/s41598-019-46735-2. PubMed PMID: 31346189; PubMed Central PMCID: PMC6658537. https://www.ncbi.nlm.nih.gov/pubmed/31346189?dopt=Abstract

4. Cembrowski MS. Single-cell transcriptomics as a framework and roadmap for understanding the brain. J Neurosci Methods. 2019 Jul 25;326:108353. doi: 10.1016/j.jneumeth.2019.108353. [Epub ahead of print] Review. PubMed PMID: 31351971. https://www.ncbi.nlm.nih.gov/pubmed/31351971?dopt=Abstract

Jul 29, Pubcrawler Hits:

1. Jobin PG, Solis N, Machado Y, Bell PA, Kwon NH, Kim S, Overall CM, Butler GS. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019 Jul 19. pii: jbc.RA119.009584. doi: 10.1074/jbc.RA119.009584. [Epub ahead of print] PubMed PMID: 31324718. https://www.ncbi.nlm.nih.gov/pubmed/31324718?dopt=Abstract

Jul 22, Pubcrawler Hits:

1. Musso PY, Junca P, Jelen M, Feldman-Kiss D, Zhang H, Chan RC, Gordon MD. Closed-loop optogenetic activation of peripheral or central neurons modulates feeding in freely moving Drosophila. Elife. 2019 Jul 19;8. pii: e45636. doi: 10.7554/eLife.45636. [Epub ahead of print] PubMed PMID: 31322499. https://www.ncbi.nlm.nih.gov/pubmed/31322499?dopt=Abstract

2. Hill L, Sumer-Bayraktar Z, Lewis JG, Morava E, Thaysen-Andersen M, Hammond GL. N-Glycosylation influences human corticosteroid-binding globulin measurements. Endocr Connect. 2019 Jul 1. pii: EC-19-0242.R1. doi: 10.1530/EC-19-0242. [Epub ahead of print] PubMed PMID: 31307013. https://www.ncbi.nlm.nih.gov/pubmed/31307013?dopt=Abstract

Jul 15, Pubcrawler Hits:

1. Andrault PM, Panwar P, Mackenzie NCW, Brömme D. Elastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification. Sci Rep. 2019 Jul 4;9(1):9682. doi: 0.1038/s41598-019-45918-1. PubMed PMID: 31273243; PubMed Central PMCID: PMC6609650. https://www.ncbi.nlm.nih.gov/pubmed/31273243?dopt=Abstract

2. Ozaki K, Thompson KJ, Simister RL, Crowe SA, Reinhard CT. Anoxygenic photosynthesis and the delayed oxygenation of Earth's atmosphere. Nat Commun. 2019 Jul 9;10(1):3026. doi: 10.1038/s41467-019-10872-z. PubMed PMID: 31289261; PubMed Central PMCID: PMC6616575. https://www.ncbi.nlm.nih.gov/pubmed/31289261?dopt=Abstract

3. Kuatsjah E, Verstraete MM, Kobylarz MJ, Liu AKN, Murphy MEP, Eltis LD. Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. J Biol Chem. 2019 Jul 10. pii: jbc.RA119.009428. doi: 10.1074/jbc.RA119.009428. [Epub ahead of print] PubMed PMID: 31292192. https://www.ncbi.nlm.nih.gov/pubmed/31292192?dopt=Abstract

4. Cait A, Cardenas E, Dimitriu P, Amenyogbe N, Dai D, Cait J, Sbihi H, Stiemsma L, Subbarao P, Mandhane PJ, Becker AB, Moraes TJ, Sears MR, Lefebvre DL, Azad MB, Kollmann T, Turvey SE, Mohn WW. Reduced genetic potential for butyrate fermentation in the gut microbiome of infants who develop allergic sensitization. J Allergy Clin Immunol. 2019 Jul 3. pii: S0091-6749(19)30891-7. doi: 10.1016/j.jaci.2019.06.029. [Epub ahead of print] PubMed PMID: 31279007. https://www.ncbi.nlm.nih.gov/pubmed/31279007?dopt=Abstract

5. Khater IM, Liu Q, Chou KC, Hamarneh G, Nabi IR. Super-resolution modularity analysis shows polyhedral caveolin-1 oligomers combine to form scaffolds and caveolae. Sci Rep. 2019 Jul 8;9(1):9888. doi: 10.1038/s41598-019-46174-z. PubMed PMID: 31285524. https://www.ncbi.nlm.nih.gov/pubmed/31285524?dopt=Abstract

6. Adams A, Yoo KM, Vogl W. Lipid transfer machinery is present at membrane contact sites associated with the internalization of junctions in Sertoli cells. Biol Reprod. 2019 Jul 11. pii: ioz120. doi: 10.1093/biolre/ioz120. [Epub ahead of print] PubMed PMID: 31292601. https://www.ncbi.nlm.nih.gov/pubmed/31292601?dopt=Abstract

Jul 8, Pubcrawler Hits:

1. Petrus P, Fernandez TL, Kwon MM, Huang JL, Lei V, Safikhan NS, Karunakaran S, O'Shannessy DJ, Zheng X, Catrina SB, Albone E, Laine J, Virtanen K, Clee SM, Kieffer TJ, Noll C, Carpentier AC, Johnson JD, Rydén M, Conway EM. Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation. EBioMedicine. 2019 Jun;44:489-501. doi: 10.1016/j.ebiom.2019.05.057. Epub 2019 Jun 17. PubMed PMID: 31221584. https://www.ncbi.nlm.nih.gov/pubmed/31221584?report=&dispmax=200&tool=PubCrawler_1.4

2. Farr Zuend C, Nomellini JF, Smit J, Horwitz MS. A Caulobacter crescentus microbicide protects from vaginal infection with HIV-1(JR-CSF) in Humanized Bone Marrow-Liver-Thymus Mice. J Virol. 2019 Jun 26. pii: JVI.00614-19. doi: 10.1128/JVI.00614-19. [Epub ahead of print] PubMed PMID: 31243127. https://www.ncbi.nlm.nih.gov/pubmed/31243127?report=&dispmax=200&tool=PubCrawler_1.4

Jul 1, Pubcrawler Hits:

1. Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, László V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szűcs M, Kuba K, Dome B, Cao Y, Haubner BJ, Penninger JM. Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy. EMBO Mol Med. 2019 Jun 24:e9266. doi: 10.15252/emmm.201809266. [Epub ahead of print] PubMed PMID: 31267692. https://www.ncbi.nlm.nih.gov/pubmed/31267692?report=&dispmax=200&tool=PubCrawler_1.4

Jun 17, Pubcrawler Hits:

1. Shah BS, Shimell JJ, Bamji SX. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J Cell Sci. 2019 Jun 12. pii: jcs.230052. doi: 10.1242/jcs.230052. [Epub ahead of print] PubMed PMID: 31189538. https://www.ncbi.nlm.nih.gov/pubmed/31189538?dopt=Abstract

2. Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG. An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nat Microbiol. 2019 Jun 10. doi: 10.1038/s41564-019-0469-7. [Epub ahead of print] PubMed PMID: 31182795. https://www.ncbi.nlm.nih.gov/pubmed/31182795?dopt=Abstract

3. Bomkamp C, Padmanabhan N, Karimi B, Ge Y, Chao JT, Loewen CJR, Siddiqui TJ, Craig AM. Mechanisms of PTPσ-Mediated Presynaptic Differentiation. Front Synaptic Neurosci. 2019 May 22;11:17. doi: 10.3389/fnsyn.2019.00017. eCollection 2019. PubMed PMID: 31191292; PubMed Central PMCID: PMC6540616. https://www.ncbi.nlm.nih.gov/pubmed/31191292?dopt=Abstract

4. Verstraete MM, Morales LD, Kobylarz MJ, Loutet SA, Laakso HA, Pinter TB, Stillman MJ, Heinrichs DE, Murphy MEP. The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus. J Biol Chem. 2019 Jun 13. pii: jbc.RA119.007757. doi: 10.1074/jbc.RA119.007757. [Epub ahead of print] PubMed PMID: 31197035. https://www.ncbi.nlm.nih.gov/pubmed/31197035?dopt=Abstract

5. Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GY. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proc Natl Acad Sci U S A. 2019 Jun 12. pii: 201900152. doi: 10.1073/pnas.1900152116. [Epub ahead of print] PubMed PMID: 31189595. https://www.ncbi.nlm.nih.gov/pubmed/31189595?dopt=Abstract

Jun 10, Pubcrawler Hits:

1. Bolger-Munro M, Choi K, Scurll JM, Abraham L, Chappell RS, Sheen D, Dang-Lawson M, Wu X, Priatel JJ, Coombs D, Hammer JA, Gold MR. Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and cell activation. Elife. 2019 Jun 3;8. pii: e44574. doi: 10.7554/eLife.44574. [Epub ahead of print] PubMed PMID: 31157616. https://www.ncbi.nlm.nih.gov/pubmed/31157616?dopt=Abstract

2. Armstrong Z, Liu F, Kheirandish S, Chen HM, Mewis K, Duo T, Morgan-Lang C, Hallam SJ, Withers SG. High-Throughput Recovery and Characterization of Metagenome-Derived Glycoside Hydrolase-Containing Clones as a Resource for Biocatalyst Development. mSystems. 2019 Jun 4;4(4). pii: e00082-19. doi: 10.1128/mSystems.00082-19. PubMed PMID: 31164449. https://www.ncbi.nlm.nih.gov/pubmed/31164449?dopt=Abstract

3. Spanier JA, Tse HM, Horwitz MS, Fife BT. Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes. Front Endocrinol (Lausanne). 2019 May 16;10:315. doi: 10.3389/fendo.2019.00315. eCollection 2019. PubMed PMID: 31156560; PubMed Central PMCID: PMC6532014. https://www.ncbi.nlm.nih.gov/pubmed/31156560?dopt=Abstract

4. Warsaba R, Sadasivan J, Jan E. Dicistrovirus-Host Molecular Interactions. Curr Issues Mol Biol. 2019 Jun 6;34:83-112. doi: 10.21775/cimb.034.083. [Epub ahead of print] PubMed PMID: 31167957. https://www.ncbi.nlm.nih.gov/pubmed/31167957?dopt=Abstract

5. Chopra S, Overall CM, Dufour A. Matrix metalloproteinases in the CNS: interferons get nervous. Cell Mol Life Sci. 2019 Jun 4. doi: 10.1007/s00018-019-03171-9. [Epub ahead of print] Review. PubMed PMID: 31165203. https://www.ncbi.nlm.nih.gov/pubmed/31165203?dopt=Abstract

6. Elling U, Woods M, Forment JV, Fu B, Yang F, Ng BL, Vicente JR, Adams DJ, Doe B, Jackson SP, Penninger JM, Balmus G. Derivation and maintenance of mouse haploid embryonic stem cells. Nat Protoc. 2019 Jun 3. doi: 10.1038/s41596-019-0169-z. [Epub ahead of print] PubMed PMID: 31160788. https://www.ncbi.nlm.nih.gov/pubmed/31160788?dopt=Abstract

Jun 03, Pubcrawler Hits:

1. Abbina S, Abbasi U, Gill A, Wong K, Kalathottukaren MT, Kizhakkedathu JN. Design of Safe Nanotherapeutics for the Excretion of Excess Systemic Toxic Iron. ACS Cent Sci. 2019 May 22;5(5):917-926. doi: 10.1021/acscentsci.9b00284. Epub 2019 Apr 11. PubMed PMID: 31139728; PubMed Central PMCID: PMC6535967. https://www.ncbi.nlm.nih.gov/pubmed/31139728?dopt=Abstract

2. Reina J, Zhou L, M Fontes MR, Panté N, Cella N. Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation. FEBS Open Bio. 2019 Mar 20. doi: 10.1002/2211-5463.12626. [Epub ahead of print] PubMed PMID: 31144423. https://www.ncbi.nlm.nih.gov/pubmed/31144423?dopt=Abstract

3. Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A, Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N, Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ, She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K, Kroemer G, Penninger JM. AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Res. 2019 May 27. doi: 10.1038/s41422-019-0181-4. [Epub ahead of print] PubMed PMID: 31133695. https://www.ncbi.nlm.nih.gov/pubmed/31133695?dopt=Abstract

May 27, Pubcrawler Hits:

1. Louca S, Scranton MI, Taylor GT, Astor YM, Crowe SA, Doebeli M. Circumventing kinetics in biogeochemical modeling. Proc Natl Acad Sci U S A. 2019 May 16. pii: doi: 10.1073/pnas.1819883116. [Epub ahead of print] PubMed PMID: https://www.ncbi.nlm.nih.gov/pubmed/31097587?dopt=Abstract

2. Jyotsana N, Sharma A, Chaturvedi A, Budida R, Scherr M, Kuchenbauer F, Lindner R, Noyan F, Sühs KW, Stangel M, Grote-Koska D, Brand K, Vornlocher HP, Eder M, Thol F, Ganser A, Humphries RK, Ramsay E, Cullis P, Heuser M. Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. Ann Hematol. 2019 May 18. doi: 10.1007/s00277-019-03713-y. [Epub ahead of print] PubMed PMID: 31104089. https://www.ncbi.nlm.nih.gov/pubmed/31104089?dopt=Abstract

3. Senini V, Amara U, Paul M, Kim H. Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis. J Periodontol. 2019 May 20. doi: 10.1002/JPER.18-0596. [Epub ahead of print] PubMed PMID: 31106406. https://www.ncbi.nlm.nih.gov/pubmed/31106406?dopt=Abstract

4. Liu B, Feng S, Dairi G, Guan Q, Chafeeva I, Wang H, Liggins R, da Roza G, Kizhakkedathu JN, Du C. Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution. BMC Nephrol. 2019 May 21; 20(1) :181. doi: 10.1186/s12882-019-1376-0. PubMed PMID: 31113397. https://www.ncbi.nlm.nih.gov/pubmed/31113397?dopt=Abstract

5. Mothersole RG, MacDonald M, Kolesnikov M, Murphy MEP, Wolthers KR. Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin. Protein Sci. 2019 May 22. doi: 10.1002/pro.3661. [Epub ahead of print] PubMed PMID: 31116469. https://www.ncbi.nlm.nih.gov/pubmed/31116469?dopt=Abstract

6. Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M. The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. PLoS One. 2019 May 23;14(5):e0216423. doi: 10.1371/journal.pone.0216423. eCollection 2019. PubMed PMID: 31120902. https://www.ncbi.nlm.nih.gov/pubmed/31120902?dopt=Abstract

7. Rabea SM, Baradaran-Heravi A, Balgi AD, Krause A, Hosseini Farahabadi S, Roberge M, Grierson DS. 2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides. ACS Med Chem Lett. 2019 Apr 9;10(5):726-731. doi: 10.1021/ acsmedchemlett.8b00610. eCollection 2019 May 9. PubMed PMID: 31097990; PubMed Central PMCID: PMC6511968. https://www.ncbi.nlm.nih.gov/pubmed/31097990?dopt=Abstract

8. Raineki C, Morgan EJ, Ellis L, Weinberg J. Glucocorticoid receptor expression in the stress-limbic circuitry is differentially affected by prenatal alcohol exposure and adolescent stress. Brain Res. 2019 May 15. pii: S0006-8993(19)30274-4. doi: 10.1016/j.brainres.2019.05.019. [Epub ahead of print] PubMed PMID: 31102593. https://www.ncbi.nlm.nih.gov/pubmed/31102593?dopt=Abstract

May 20, Pubcrawler Hits:

1. Macdonald SS, Armstrong Z, Morgan-Lang C, Osowiecka M, Robinson K, Hallam SJ, Withers SG. Development and Application of a High-Throughput Functional Metagenomic Screen for Glycoside Phosphorylases. Cell Chem Biol. 2019 May 9. pii: S2451-9456(19)30113-8. doi: 10.1016/j.chembiol.2019.03.017. [Epub ahead of print] PubMed PMID: 31080075. https://www.ncbi.nlm.nih.gov/pubmed/31080075?dopt=Abstract

2. Lau GY, Barts N, Hartley RC, Tobler M, Richards JG, Murphy MP, Arndt S. Detection of changes in mitochondrial hydrogen sulfide in vivo in the fish model Poecilia mexicana (Poeciliidae). Biol Open. 2019 May 9;8(5). pii: bio041467. doi: 10.1242/bio.041467. PubMed PMID: 31072908. https://www.ncbi.nlm.nih.gov/pubmed/31072908?dopt=Abstract

3. Gardill BR, Rivera-Acevedo RE, Tung CC, Van Petegem F. Crystal structures of Ca(2+)-calmodulin bound to Na(V) C-terminal regions suggest role for EF-hand domain in binding and inactivation. Proc Natl Acad Sci U S A. 2019 May 9. pii: 201818618. doi: 10.1073/pnas.1818618116. [Epub ahead of print] PubMed PMID: 31072926. https://www.ncbi.nlm.nih.gov/pubmed/31072926?dopt=Abstract

4. Katsube M, Rolfe SM, Bortolussi SR, Yamaguchi Y, Richman JM, Yamada S, Vora SR. Analysis of facial skeletal asymmetry during foetal development using μCT imaging. Orthod Craniofac Res. 2019 May;22 Suppl 1:199-206. doi: 10.1111/ocr.12304. PubMed PMID: 31074127; PubMed Central PMCID: PMC6512839. https://www.ncbi.nlm.nih.gov/pubmed/31074127?dopt=Abstract

5. McSwiggen DT, Hansen AS, Teves SS, Marie-Nelly H, Hao Y, Heckert AB, Umemoto KK, Dugast-Darzacq C, Tjian R, Darzacq X. Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. Elife. 2019 May 7;8. pii: e47098. doi: 10.7554/eLife.47098. PubMed PMID: 31038454. https://www.ncbi.nlm.nih.gov/pubmed/31038454?dopt=Abstract

May 13, Pubcrawler Hits:

1. Frirdich E, Biboy J, Pryjma M, Lee J, Huynh S, Parker CT, Girardin SE, Vollmer W, Gaynor EC. The Campylobacter jejuni helical to coccoid transition involves changes to peptidoglycan and the ability to elicit an immune response. Mol Microbiol. 2019 May 9. doi: 10.1111/mmi.14269. [Epub ahead of print] PubMed PMID: 31070821. https://www.ncbi.nlm.nih.gov/pubmed/31070821?dopt=Abstract

2. Ehrhardt K, Steck N, Kappelhoff R, Stein S, Rieder F, Gordon IO, Boyle EC, Braubach P, Overall CM, Finlay BB, Grassl GA. Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis. Inflamm Bowel Dis. 2019 May 9. pii: izz070. doi: 10.1093/ibd/izz070. [Epub ahead of print] PubMed PMID: 31066456. https://www.ncbi.nlm.nih.gov/pubmed/31066456?dopt=Abstract

3. Haji-Ghassemi O, Yuchi Z, Van Petegem F. The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner. Mol Cell. Published: May 08, 2019DOI:https://doi.org/10.1016/j.molcel.2019.04.019

4. Tamura K, Foley MH, Gardill BR, Dejean G, Schnizlein M, Bahr CME, Louise Creagh A, van Petegem F, Koropatkin NM, Brumer H. Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cell Mol Life Sci. 2019 May 6. doi: 10.1007/s00018-019-03115-3. [Epub ahead of print] PubMed PMID: 31062073. https://www.ncbi.nlm.nih.gov/pubmed/31062073?dopt=Abstract

5. Caveney NA, Pavlin A, Caballero G, Bahun M, Hodnik V, de Castro L, Fornelos N, Butala M, Strynadka NCJ. Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure. 2019 Apr 10. pii: S0969-2126(19)30115-7. doi: 10.1016/j.str.2019.03.019. [Epub ahead of print] PubMed PMID: 31056420. https://www.ncbi.nlm.nih.gov/pubmed/31056420?dopt=Abstract

May 06, Pubcrawler Hits:

1. Gold MR, Reth MG. Antigen Receptor Function in the Context of the Nanoscale Organization of the B Cell Membrane. Annu Rev Immunol. 2019 Apr 26;37:97-123. doi: 10.1146/annurev-immunol-042718-041704. PubMed PMID: 31026412. https://www.ncbi.nlm.nih.gov/pubmed/31026412?dopt=Abstract

2. Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, Liu C, Walker CL, Jonasch E, Lefebvre L, Wu M, Lorincz MC, Li W, Li L, Xie W. SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development. Nat Genet. 2019 May;51(5):844-856. doi: 10.1038/s41588-019-0398-7. Epub 2019 Apr 29. PubMed PMID: 31040401. https://www.ncbi.nlm.nih.gov/pubmed/31040401?dopt=Abstract

3. Hendi A, Kurashina M, Mizumoto K. Intrinsic and extrinsic mechanisms of synapse formation and specificity in C. elegans. Cell Mol Life Sci. 2019 Apr 29. doi: 10.1007/s00018-019-03109-1. [Epub ahead of print] Review. https://www.ncbi.nlm.nih.gov/pubmed/31037336?dopt=Abstract

4. Gignac SJ, Hosseini-Farahabadi S, Akazawa T, Schuck NJ, Fu K, Richman JM. Robinow syndrome skeletal phenotypes caused by the WNT5AC83S variant are due to dominant interference with chondrogenesis. Hum Mol Genet. 2019 Apr 3. pii: ddz071. doi: 10.1093/hmg/ddz071. [Epub ahead of print] PubMed PMID: 31032853. https://www.ncbi.nlm.nih.gov/pubmed/31032853?dopt=Abstract

April 29, Pubcrawler Hits:

1. Conway EM. Polyphosphates and Complement Activation. Front Med (Lausanne). 2019 Apr 4;6:67. doi: 10.3389/fmed.2019.00067. eCollection 2019. Review. PubMed PMID: 31019911; PubMed Central PMCID: PMC6458250. https://www.ncbi.nlm.nih.gov/pubmed/31019911?dopt=Abstract

2. Kulkarni JA, Witzigmann D, Leung J, van der Meel R, Zaifman J, Darjuan MM, Grisch-Chan HM, Thöny B, Tam YYC, Cullis PR. Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads. Nanoscale. 2019 Apr 25. doi: 10.1039/c9nr02004g. [Epub ahead of print] PubMed PMID: 31021343. https://www.ncbi.nlm.nih.gov/pubmed/31021343?dopt=Abstract

3. Caveney NA, Caballero G, Voedts H, Niciforovic A, Worrall LJ, Vuckovic M, Fonvielle M, Hugonnet JE, Arthur M, Strynadka NCJ. Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun. 2019 Apr 23;10(1):1849. doi: 10.1038/s41467-019-09507-0. PubMed PMID: 31015395; PubMed Central PMCID: PMC6478713. https://www.ncbi.nlm.nih.gov/pubmed/31015395?dopt=Abstract

April 23, Pubcrawler Hits:

1. Kaner Z, Engelman R, Schuster R, Rider P, Greenberg D, Av-Gay Y, Benhar M, Lewis EC. S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination. Front Immunol. 2019 Apr 2;10:590. doi: 10.3389/fimmu.2019.00590. eCollection 2019. PubMed PMID: 31001247; PubMed Central PMCID: PMC6454134. https://www.ncbi.nlm.nih.gov/pubmed/31001247?dopt=Abstract

2. Geletu M, Taha Z, Arulanandam R, Mohan R, Assi HH, Castro MG, Nabi IR, Gunning PT, Raptis L PhD. Effect of Caveolin-1 upon Stat3-ptyr705 levels in breast and lung carcinoma cells. Biochem Cell Biol. 2019 Apr 15. doi: 10.1139/bcb-2018-0367. [Epub ahead of print] PubMed PMID: 30986357.

3. Trudel D, Avarvarei LM, Orain M, Turcotte S, Plante M, Grégoire J, Kappelhoff  R, Labbé DP, Bachvarov D, Têtu B, Overall CM, Bairati I. Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer. Pathol Res Pract. 2019 Mar 2. pii: S0344-0338(18)31674-1. doi: 10.1016/j.prp.2019.02.019. [Epub ahead of print] PubMed PMID: 30987833.https://www.ncbi.nlm.nih.gov/pubmed/30987833?dopt=Abstract

4. Paik YK, Overall CM, Corrales F, Deutsch EW, Lane L, Omenn GS. Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods. J Proteome Res. 2018 Dec 7;17(12):4023-4030. doi: 10.1021/acs.jproteome.8b00885. PubMed PMID: 30985145; PubMed Central PMCID: PMC6288998. https://www.ncbi.nlm.nih.gov/pubmed/30985145?dopt=Abstract

5. Fu L, Haage A, Kong N, Tanentzapf G, Li H. Dynamic protein hydrogels with reversibly tunable stiffness regulate human lung fibroblast spreading reversibly. Chem Commun (Camb). 2019 Apr 15. doi: 10.1039/c9cc01276a. [Epub ahead of print] PubMed PMID: 30984936. https://www.ncbi.nlm.nih.gov/pubmed/30984936?dopt=Abstract

April 15, Pubcrawler Hits:

1. Khadilkar RJ, Tanentzapf G. Septate junction components control Drosophila hematopoiesis through the Hippo pathway. Development. 2019 Apr 4;146(7). pii: dev166819. doi: 10.1242/dev.166819. PubMed PMID: 30890573. https://www.ncbi.nlm.nih.gov/pubmed/30890573?dopt=Abstract

April 8, Pubcrawler Hits:

1. Westhoff M, Eldstrom J, Murray CI, Thompson E, Fedida D. I (Ks) ion-channel pore conductance can result from individual voltage sensor movements. Proc Natl Acad Sci U S A. 2019 Mar 27. pii: 201811623. doi: 10.1073/pnas.1811623116. [Epub ahead of print] PubMed PMID: 30918124. https://www.ncbi.nlm.nih.gov/pubmed/30918124?dopt=Abstract

2. Au Yeung WK, Brind'Amour J, Hatano Y, Yamagata K, Feil R, Lorincz MC, Tachibana M, Shinkai Y, Sasaki H. Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection. Cell Rep. 2019 Apr 2;27(1):282-293.e4. doi: 10.1016/j.celrep.2019.03.002. PubMed PMID: 30943408. https://www.ncbi.nlm.nih.gov/pubmed/30943408?dopt=Abstract

3. Conroy BS, Grigg JC, Kolesnikov M, Morales LD, Murphy MEP. Staphylococcus aureus heme and siderophore-iron acquisition pathways. Biometals. 2019 Mar 25. doi: 10.1007/s10534-019-00188-2. [Epub ahead of print] PubMed PMID: 30911924. https://www.ncbi.nlm.nih.gov/pubmed/30911924?dopt=Abstract

4. Conroy BS, Grigg JC, Kolesnikov M, Morales LD, Murphy MEP. Staphylococcus aureus heme and siderophore-iron acquisition pathways. Biometals. 2019 Mar 25. doi: 10.1007/s10534-019-00188-2. [Epub ahead of print] PubMed PMID: 30911924. https://www.ncbi.nlm.nih.gov/pubmed/30911924?dopt=Abstract

5. Basson R, O'Loughlin JI, Weinberg J, Young AH, Bodnar T, Brotto LA. Dehydroepiandrosterone and cortisol as markers of HPA axis dysregulation in women with low sexual desire. Psychoneuroendocrinology. 2019 Mar 8;104:259-268. doi: 10.1016/j.psyneuen.2019.03.001. [Epub ahead of print] PubMed PMID: 30909007. https://www.ncbi.nlm.nih.gov/pubmed/30909007?dopt=Abstract

6. Buck J, Grossen P, Cullis PR, Huwyler J, Witzigmann D. Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery. ACS Nano. 2019 Apr 2. doi: 10.1021/acsnano.8b07858. [Epub ahead of print] PubMed PMID: 30908008. https://www.ncbi.nlm.nih.gov/pubmed/30908008?dopt=Abstract

March. 25, Pubcrawler Hits:

1. Ding H, Saer RG, Beatty JT. Porphyrin Excretion Resulting From Mutation of a Gene Encoding a Class I Fructose 1,6-Bisphosphate Aldolase in Rhodobacter capsulatus. Front Microbiol. 2019 Feb 22;10:301. doi: 10.3389/fmicb.2019.00301. eCollection 2019. PubMed PMID: 30853951; PubMed Central PMCID: PMC6395792. https://www.ncbi.nlm.nih.gov/pubmed/30853951?dopt=Abstract

2. Liou AY, Molday LL, Wang J, Andersen JP, Molday RS. Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. J Biol Chem. 2019 Mar 8. pii: jbc.RA118.007270. doi: 10.1074/jbc.RA118.007270. [Epub ahead of print] PubMed PMID: 30850395. https://www.ncbi.nlm.nih.gov/pubmed/30850395?dopt=Abstract

3. Freitas-Andrade M, Wang N, Bechberger JF, De Bock M, Lampe PD, Leybaert L, Naus CC. Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke. J Exp Med. 2019 Mar 14. pii: jem.20171452. doi: 10.1084/jem.20171452. [Epub ahead of print] PubMed PMID: 30872361. https://www.ncbi.nlm.nih.gov/pubmed/30872361

4. Le Vasseur M, Chen VC, Huang K, Vogl WA, Naus CC. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers (Basel). 2019 Mar 11;11(3). pii: E343. doi: 10.3390/cancers11030343. PubMed PMID: 30862038. https://www.ncbi.nlm.nih.gov/pubmed/30862038

5. Shafaattalab S, Li AY, Lin E, Stevens CM, Dewar LJ, Lynn FC, Sanatani S, Laksman Z, Morin RD, van Petegem F, Hove-Madsen L, Tieleman DP, Davis JP, Tibbits GF. In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants. Proc Natl Acad Sci U S A. 2019 Mar 18. pii: 201819023. doi: 10.1073/pnas.1819023116. [Epub ahead of print] PubMed PMID: 30886088. https://www.ncbi.nlm.nih.gov/pubmed/30886088?dopt=Abstract

6. Bowerman B, Sugioka K. Breaking Symmetry: Worm Cue Finally Found. Dev Cell. 2019 Mar 11;48(5):593-594. doi: 10.1016/j.devcel.2019.02.018. PubMed PMID: 30861371. https://www.ncbi.nlm.nih.gov/pubmed/30861371?dopt=Abstract

March. 11, Pubcrawler Hits:

1. Glavas MM, Hui Q, Tudurí E, Erener S, Kasteel NL, Johnson JD, Kieffer TJ. Early overnutrition reduces Pdx1 expression and induces β cell failure in Swiss Webster mice. Sci Rep. 2019 Mar 6; 9(1):3619. doi: 10.1038/s41598-019-39177-3. PubMed PMID: 30842440. https://www.ncbi.nlm.nih.gov/pubmed/30842440?dopt=Abstract

2. Latres E, Finan DA, Greenstein JL, Kowalski A, Kieffer TJ. Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy. Cell Metab. 2019 Mar 5; 29(3):545-563. doi: 10.1016/j.cmet.2019.02.007. Review. PubMed PMID: 30840911. https://www.ncbi.nlm.nih.gov/pubmed/30840911?dopt=Abstract

3. Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. Sci Rep. 2019 Mar 5; 9(1):3594. doi: 10.1038/s41598-019-40136-1. PubMed PMID: 30837605; PubMed Central PMCID: PMC6401103. https://www.ncbi.nlm.nih.gov/pubmed/30837605?dopt=Abstract

4. Pereira S, O'Dwyer SM, Webber TD, Baker RK, So V, Ellis CE, Yoon JS, Mojibian M, Glavas MM, Karunakaran S, Clee SM, Covey SD, Kieffer TJ. Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues. Sci Rep. 2019 Mar 1; 9(1):3307. doi: 10.1038/s41598-019-39498-3. PubMed PMID: 30824713; PubMed Central PMCID: PMC6397253. https://www.ncbi.nlm.nih.gov/pubmed/30824713?dopt=Abstract

5. Holman PJ, Baglot SL, Morgan E, Weinberg J. Effects of prenatal alcohol exposure on social competence: Asymmetry in play partner preference among heterogeneous triads of male and female rats. Dev Psychobiol. 2019 Mar 6. doi: 10.1002/dev.21842. [Epub ahead of print] PubMed PMID: 30843198. https://www.ncbi.nlm.nih.gov/pubmed/30843198?dopt=Abstract

7. Eid RS, Chaiton JA, Lieblich SE, Bodnar TS, Weinberg J, Galea LAM. Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu. Neurobiol Aging. 2019 Feb 2; 78:1-17. doi: 10.1016/j.neurobiolaging.2019.01.021. [Epub ahead of print] PubMed PMID: 30825663. https://www.ncbi.nlm.nih.gov/pubmed/30825663?dopt=Abstract

8. Borrel G, Adam PS, McKay LJ, Chen LX, Sierra-García IN, Sieber CMK, Letourneur Q, Ghozlane A, Andersen GL, Li WJ, Hallam SJ, Muyzer G, de Oliveira VM, Inskeep WP, Banfield JF, Gribaldo S. Wide diversity of methane and short-chain alkane metabolisms in uncultured archaea. Nat Microbiol. 2019 Mar 4. doi: 10.1038/s41564-019-0363-3. [Epub ahead of print] PubMed PMID: 30833729. https://www.ncbi.nlm.nih.gov/pubmed/30833729?dopt=Abstract

Feb. 25, Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Baldry SEL, Yang C, Tosefsky K, Balaton BP, Simpson EM, Brown CJ. How do genes that escape from X-chromosome inactivation contribute to Turner syndrome? Am J Med Genet C Semin Med Genet. 2019 Feb 19. doi: 10.1002/ajmg.c.31672. [Epub ahead of print] PubMed PMID: 30779428. https://www.ncbi.nlm.nih.gov/pubmed/30779428?dopt=Abstract

2. Cait J, Hughes MR, Zeglinski MR, Chan AW, Osterhof S, Scott RW, Canals Hernaez D, Cait A, Vogl AW, Bernatchez P, Underhill TM, Granville DJ, Murphy TH, Roskelley CD, McNagny KM. Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation. Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 201814766. doi: 10.1073/pnas.1814766116. [Epub ahead of print] PubMed PMID: 30787191. https://www.ncbi.nlm.nih.gov/pubmed/30787191?dopt=Abstract

Feb. 18, Pubcrawler Hits:

1. Haw J, Polzer J, Devine DV. Contextual factors influencing donor recruitment and cord blood collection: perspectives of frontline staff of the Canadian Blood Services' Cord Blood Bank. Transfusion. 2019 Feb 11. doi: 10.1111/trf.15185. [Epub ahead of print] PubMed PMID: 30741433. https://www.ncbi.nlm.nih.gov/pubmed/30741433?dopt=Abstract

2. Navas LE, Martínez FD, Taverna ME, Fetherolf MM, Eltis LD, Nicolau V, Estenoz D, Campos E, Benintende GB, Berretta MF. A thermostable laccase from Thermus sp. 2.9 and its potential for delignification of Eucalyptus biomass. AMB Express. 2019 Feb 12;9(1):24. doi: 10.1186/s13568-019-0748-y. PubMed PMID: 30756202. https://www.ncbi.nlm.nih.gov/pubmed/30756202?dopt=Abstract

3. Mikkelsen SA, Mogensen LS, Vilsen B, Molday RS, Vestergaard AL, Andersen JP. Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. J Biol Chem. 2019 Feb 13. pii: jbc.RA118.007240. doi: 10.1074/jbc.RA118.007240. [Epub ahead of print] PubMed PMID: 30760526. https://www.ncbi.nlm.nih.gov/pubmed/30760526?dopt=Abstract

4. Soni A, Lin C, Murphy M, Tanner ME. Peptides Containing meso-Oxa-Diaminopimelic Acid as Substrates for the Cell Shape-Determining Proteases Csd6 and Pgp2. Chembiochem. 2019 Feb 11. doi: 10.1002/cbic.201900011. [Epub ahead of print] PubMed PMID: 30746833. https://www.ncbi.nlm.nih.gov/pubmed/30746833?dopt=Abstract

5. Khater IM, Meng F, Nabi IR, Hamarneh G. Identification of Caveolin-1 Domain Signatures via Graphlet Analysis of Single Molecule Super-Resolution Data. Bioinformatics. 2019 Feb 13. doi: 10.1093/bioinformatics/btz113. [Epub ahead of print] PubMed PMID: 30759191. https://www.ncbi.nlm.nih.gov/pubmed/30759191?dopt=Abstract

6. Majewski DD, Worrall LJ, Hong C, Atkinson CE, Vuckovic M, Watanabe N, Yu Z, Strynadka NCJ. Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry. Nat Commun. 2019 Feb 7;10(1):626. doi: 10.1038/s41467-019-08477-7. PubMed PMID: 30733444; PubMed Central PMCID: PMC6367419.  https://www.ncbi.nlm.nih.gov/pubmed/30733444?dopt=Abstract

7. Xu M, Singla J, Tocheva EI, Chang YW, Stevens RC, Jensen GJ, Alber F. De Novo Structural Pattern Mining in Cellular Electron Cryotomograms. Structure. 2019 Jan 31. pii: S0969-2126(19)30005-X. doi: 10.1016/j.str.2019.01.005. [Epub ahead of print] PubMed PMID: 30744995. https://www.ncbi.nlm.nih.gov/pubmed/30744995?dopt=Abstract

Feb. 11, Pubcrawler Hits:

1. Yang X, Kang N, Toyofuku WM, Scott MD. Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics. Immunobiology. 2018 Dec 28. pii: S0171-2985(18)30124-4. doi: 1016/j.imbio.2018.12.003. [Epub ahead of print] PubMed PMID: 30711357.  https://www.ncbi.nlm.nih.gov/pubmed/30711357?dopt=Abstract

2. Maya-Martinez R, Alexander JAN, Otten CF, Ayala I, Vollmer D, Gray J, Bougault CM, Burt A, Laguri C, Fonvielle M, Arthur M, Strynadka NCJ, Vollmer W, Simorre JP. Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus. Front Microbiol. 2019 Jan 18;9:3223. doi: 10.3389/fmicb.2018.03223. eCollection 2018. PubMed PMID: 30713527; PubMed Central PMCID: PMC6346638. https://www.ncbi.nlm.nih.gov/pubmed/30713527?dopt=Abstract

Feb. 04, Pubcrawler Hits:

1. Tamaru Y, Yoshida M, Eltis LD, Goodell B. Multiple iron reduction by methoxylated phenolic lignin structures and the generation of reactive oxygen species by lignocellulose surfaces. Int J Biol Macromol. 2019 Jan 27;128:340-346. doi: 10.1016/j.ijbiomac.2019.01.149. [Epub ahead of print] PubMed PMID: 30699335.  https://www.ncbi.nlm.nih.gov/pubmed/30699335?dopt=Abstract

2. Quancard J, Klein T, Fung SY, Renatus M, Hughes N, Israël L, Priatel JJ, Kang S, Blank MA, Viner RI, Blank J, Schlapbach A, Erbel P, Kizhakkedathu J, Villard F, Hersperger R, Turvey SE, Eder J, Bornancin F, Overall CM. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Jan 28. doi: 10.1038/s41589-018-0222-1. [Epub ahead of print] PubMed PMID: 30692685. https://www.ncbi.nlm.nih.gov/pubmed/30692685?dopt=Abstract

3. Zeytuni N, Strynadka NCJ. A Hybrid Secretion System Facilitates Bacterial Sporulation: A Structural Perspective. Microbiol Spectr. 2019 Jan;7(1). doi: 10.1128/microbiolspec.PSIB-0013-2018. PubMed PMID: 30681070. https://www.ncbi.nlm.nih.gov/pubmed/30681070?dopt=Abstract

4. Arenaz-Callao MP, González Del Río R, Lucía Quintana A, Thompson CJ, Mendoza-Losana A, Ramón-García S. Triple oral beta-lactam containing therapy for  Buruli ulcer treatment shortening. PLoS Negl Trop Dis. 2019 Jan 28; 13(1):e0007126. doi: 10.1371/journal.pntd.0007126. [Epub ahead of print] PubMed PMID: 30689630. https://www.ncbi.nlm.nih.gov/pubmed/30689630?dopt=Abstract

Jan. 21, Pubcrawler Hits:

1. Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ. Author Correction: A compendium of geochemical information from the Saanich Inlet water column. Sci Data. 2019 Jan 15; 6(1):1. doi: 10.1038/s41597-018-0005-2. PubMed PMID: 30647409; PubMed Central PMCID: PMC6333813. https://www.ncbi.nlm.nih.gov/pubmed/30647409?dopt=Abstract

2. Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, Lindenhofer D, Chen G, Boehm M, Agu CA, Yang F, Fu B, Zuber J, Knoblich JA, Kerjaschki D, Penninger JM. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019 Jan 16. doi: 10.1038/s41586-018-0858-8. [Epub ahead of print] PubMed PMID: 30651639. https://www.ncbi.nlm.nih.gov/pubmed/30651639?dopt=Abstract

Jan. 14, Pubcrawler Hits:

1. Law S, Du X, Panwar P, Honson NS, Pfeifer T, Roberge M, Brömme D.Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening. Biochem J. 2019 Jan 8. pii: BCJ20180851. doi: 10.1042/BCJ20180851. [Epub ahead of print] PubMed PMID: 30622151. https://www.ncbi.nlm.nih.gov/pubmed/30622151?dopt=Abstract

2. Spitalnik SL, Devine DV. Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains. Transfusion. 2019 Jan;59(1):2-5. doi: 10.1111/trf.15066. PubMed PMID: 30615814. https://www.ncbi.nlm.nih.gov/pubmed/30615814?dopt=Abstract

3. Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2018 Dec 21. pii: S0092-8674(18)31560-5. doi: 10.1016/j.cell.2018.11.035. [Epub ahead of print] PubMed PMID: 30612739. https://www.ncbi.nlm.nih.gov/pubmed/30612739?dopt=Abstract

4. Lo BC, Shin SB, Canals Hernaez D, Refaeli I, Yu HB, Goebeler V, Cait A, Mohn WW, Vallance BA, McNagny KM. IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella Infection. J Immunol. 2019 Jan 7. pii: ji1801308. doi: 10.4049/jimmunol.1801308. [Epub ahead of print] PubMed PMID: 30617224. https://www.ncbi.nlm.nih.gov/pubmed/30617224?dopt=Abstract

5. Yang H, Li Y, Zhao M, Wu F, Wang X, Xiao W, Wang Y, Zhang J, Wang F, Xu F, Zeng WF, Overall CM, He SM, Chi H, Xu P. Precision de novo peptide sequencing using mirror proteases of Ac-LysargiNase and trypsin for large-scale proteomics. Mol Cell Proteomics. 2019 Jan 8. pii: mcp.TIR118.000918. doi: 10.1074/mcp.TIR118.000918. [Epub ahead of print] PubMed PMID: 30622160. https://www.ncbi.nlm.nih.gov/pubmed/30622160?dopt=Abstract

6. Ng MY, Zhang H, Weil A, Singh V, Jamiolkowski R, Baradaran-Heravi A, Roberge M, Jacobson A, Friesen W, Welch E, Goldman YE, Cooperman BS. New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. ACS Med Chem Lett. 2018 Nov 21;9(12):1285-1291. doi: 10.1021/acsmedchemlett.8b00472. eCollection 2018 Dec 13. PubMed PMID: 30613341; PubMed Central PMCID: PMC6295867. https://www.ncbi.nlm.nih.gov/pubmed/30613341?dopt=Abstract

Jan. 07, Pubcrawler Hits:

1. Sturm A, Fowle DA, Jones C, Leslie K, Nomosatryo S, Henny C, Canfield DE, Crowe SA. Rates and pathways of CH(4) oxidation in ferruginous Lake Matano, Indonesia. Geobiology. 2018 Dec 28. doi: 10.1111/gbi.12325. [Epub ahead of print] PubMed PMID: 30593722. https://www.ncbi.nlm.nih.gov/pubmed/30593722?dopt=Abstract

2. Young J, Duong F. Investigating the stability of the SecA-SecYEG complex during protein translocation across the bacterial membrane. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006447. doi: 10.1074/jbc.RA118.006447. [Epub ahead of print] PubMed PMID: 30602566. https://www.ncbi.nlm.nih.gov/pubmed/30602566?dopt=Abstract

3. Perez-Borrajero C, Lin CS, Okon M, Scheu K, Graves BJ, Murphy MEP, McIntosh LP. The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J Mol Biol. 2018 Dec 28. pii: S0022-2836(18)31286-5. doi: 10.1016/j.jmb.2018.12.011. [Epub ahead of print] PubMed PMID: 30597162. https://www.ncbi.nlm.nih.gov/pubmed/30597162?dopt=Abstract

4. Zimmermann P, Messina N, Mohn WW, Finlay BB, Curtis N. Association between the intestinal microbiota and allergic sensitization, eczema, and asthma: A systematic review. J Allergy Clin Immunol. 2018 Dec 29. pii: S0091-6749(18)31431-3. doi: 10.1016/j.jaci.2018.09.025. [Epub ahead of print] PubMed PMID: 30600099. https://www.ncbi.nlm.nih.gov/pubmed/30600099?dopt=Abstract

5. Richman JM. Shedding new light on the mysteries of tooth eruption. Proc Natl Acad Sci U S A. 2019 Jan 2. pii: 201819412. doi: 10.1073/pnas.1819412116. [Epub ahead of print] PubMed PMID: 30602459. https://www.ncbi.nlm.nih.gov/pubmed/30602459?dopt=Abstract

Dec. 31, Pubcrawler Hits:

1. Kajiwara Y, Wang E, Wang M, Sin WC, Brennand KJ, Schadt E, Naus CC, Buxbaum J, Zhang B. GJA1 (connexin43) is a key regulator of Alzheimer's disease pathogenesis. Acta Neuropathol Commun. 2018 Dec 21;6(1):144. doi: 10.1186/s40478-018-0642-x. PubMed PMID: 30577786. https://www.ncbi.nlm.nih.gov/pubmed/30577786?report=&dispmax=200&tool=PubCrawler_1.4

2. Johnson SB, Emmons EB, Lingg RT, Anderson RM, Romig-Martin SA, LaLumiere RT, Narayanan NS, Viau V, Radley JJ. Prefrontal-bed nucleus circuit modulation of a passive coping response set. J Neurosci. 2018 Dec 20. pii: 1421-18. doi: 10.1523/JNEUROSCI.1421-18.2018. [Epub ahead of print] PubMed PMID: 30573644. https://www.ncbi.nlm.nih.gov/pubmed/30573644?report=&dispmax=200&tool=PubCrawler_1.4

Dec. 24, Pubcrawler Hits:

1. Johnson P, Arif AA, Lee-Sayer SSM, Dong Y. Hyaluronan and Its Interactions With Immune Cells in the Healthy and Inflamed Lung. Front Immunol. 2018 Nov 29; 9:2787. doi: 10.3389/fimmu.2018.02787. eCollection 2018. Review. PubMed PMID: 30555472; PubMed Central PMCID: PMC6281886. https://www.ncbi.nlm.nih.gov/pubmed/30555472?dopt=Abstract

2. Modi H, Johnson JD. Folding mutations suppress early beta-cell proliferation. Elife. 2018 Dec 14; 7. pii: e43475. doi: 10.7554/eLife.43475. PubMed PMID: 30547883; PubMed Central PMCID: PMC6294546. https://www.ncbi.nlm.nih.gov/pubmed/30547883?dopt=Abstract

3. Liu KYP, Lu XJD, Zhu YS, Le N, Kim H, Poh CF. Plasma-Derived Inflammatory Proteins Predict Oral Squamous Cell Carcinoma. Front Oncol. 2018 Dec 4; 8:585. doi: 10.3389/fonc.2018.00585. eCollection 2018. PubMed PMID: 30564558; PubMed Central PMCID: PMC6288174. https://www.ncbi.nlm.nih.gov/pubmed/30564558?dopt=Abstract

4. Chohan H, Esfandiarei M, Arman D, Van Raamsdonk CD, van Breemen C, Friedman JM, Jett KA. Neurofibromin haploinsufficiency results in altered spermatogenesis in a mouse model of neurofibromatosis type 1. PLoS One. 2018 Dec 20; 13(12):e0208835. doi: 10.1371/journal.pone.0208835. eCollection 2018. PubMed PMID: 30571760. https://www.ncbi.nlm.nih.gov/pubmed/30571760?dopt=Abstract

5. Lussier AA, Bodnar TS, Mingay M, Morin AM, Hirst M, Kobor MS, Weinberg J. Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues. Front Genet. 2018 Dec 4;9:610. doi: 10.3389/fgene.2018.00610. eCollection 2018. PubMed PMID: 30568673; PubMed Central PMCID: PMC6290329. https://www.ncbi.nlm.nih.gov/pubmed/30568673?dopt=Abstract

Dec. 17, Pubcrawler Hits:

1. Ng KW, Marshall EA, Enfield KS, Martin SD, Milne K, Pewarchuk ME, Abraham N, Lam WL. Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma. Oncoimmunology. 2018 Sep 6;7(12):e1504728. doi: 10.1080/2162402X.2018.1504728. eCollection 2018. PubMed PMID: 30524903; PubMed Central PMCID: PMC6279324. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279324/

2. Levy-Booth DJ, Giesbrecht IJW, Kellogg CTE, Heger TJ, D'Amore DV, Keeling PJ, Hallam SJ, Mohn WW. Seasonal and ecohydrological regulation of active microbial populations involved in DOC, CO(2), and CH(4) fluxes in temperate rainforest soil. ISME J. 2018 Dec 11. doi: 10.1038/s41396-018-0334-3. [Epub ahead of print] PubMed PMID: 30538276. https://www.ncbi.nlm.nih.gov/pubmed/30538276?dopt=Abstract

3. Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM. The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2018 Nov 29. pii: S0085-2538(18)30644-6. doi: 10.1016/j.kint.2018.08.037. [Epub ahead of print] PubMed PMID: 30522767. https://www.ncbi.nlm.nih.gov/pubmed/30522767?dopt=Abstract

4. Brockerman JA, Okon M, Withers SG, McIntosh LP. The pK(a) values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme. Protein Sci. 2018 Dec 7. doi: 10.1002/pro.3562. [Epub ahead of print] PubMed PMID: 30537432. https://www.ncbi.nlm.nih.gov/pubmed/30537432?dopt=Abstract

5. Ipsiroglu OS, Wind K, Hung YA, Berger M, Chan F, Yu W, Stockler S, Weinberg J. Prenatal alcohol exposure and sleep-wake behaviors: exploratory and naturalistic observations in the clinical setting and in an animal model. Sleep Med. 2018 Oct 25;54:101-112. doi: 10.1016/j.sleep.2018.10.006. [Epub ahead of print] PubMed PMID: 30530254. https://www.ncbi.nlm.nih.gov/pubmed/30530254?dopt=Abstract

Dec. 10, Pubcrawler Hits:

1. Pawluski JL, Brain U, Hammond GL, Oberlander TF. Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression. Arch Womens Ment Health. 2018 Dec 1. doi: 10.1007/s00737-018-0931-1. [Epub ahead of print] PubMed PMID: 30506371. https://www.ncbi.nlm.nih.gov/pubmed/30506371?dopt=Abstract

Dec. 03, Pubcrawler Hits:

1. Vuilleumier R, Lian T, Flibotte S, Khan ZN, Fuchs A, Pyrowolakis G, Allan DW. Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element. Nucleic Acids Res. 2018 Nov 22. doi: 10.1093/nar/gky1135. [Epub ahead of print] PubMed PMID: 30476189. https://www.ncbi.nlm.nih.gov/pubmed/30476189?dopt=Abstract

2. Kerr CH, Dalwadi U, Scott NE, Yip CK, Foster LJ, Jan E. Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells. Sci Rep. 2018 Nov 26;8(1):17353. doi: 10.1038/s41598-018-35717-5. PubMed PMID: 30478341. https://www.ncbi.nlm.nih.gov/pubmed/30478341?dopt=Abstract

3. Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G. Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo. Cell Rep. 2018 Nov 27;25(9):2401-2416.e5. doi: 10.1016/j.celrep.2018.10.098. PubMed PMID: 30485809. https://www.ncbi.nlm.nih.gov/pubmed/30485809?dopt=Abstract

Nov. 26, Pubcrawler Hits:

1. González A, Fernandino JI, Elisio M, Chalde T, Miranda LA, Hammond GL, Somoza GM. Sex Hormone Binding Globuling during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis). Gen Comp Endocrinol. 2018 Nov 19. pii: S0016-6480(18)30365-4. doi: 10.1016/j.ygcen.2018.11.010. [Epub ahead of print] PubMed PMID: 30465767. https://www.ncbi.nlm.nih.gov/pubmed/30465767?dopt=Abstract

2. Tunster SJ, Van de Pette M, Creeth HDJ, Lefebvre L, John RM. Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome. Dis Model
Mech. 2018 Nov 16;11(11). pii: dmm035832. doi: 10.1242/dmm.035832. PubMed PMID: 30158284; PubMed Central PMCID: PMC6262809. https://www.ncbi.nlm.nih.gov/pubmed/30158284

3. Hill LA, Vassiliadi DA, Dimopoulou I, Anderson AJ, Boyle LD, Kilgour AHM, Stimson RH, Machado Y, Overall CM, Walker BR, Lewis JG, Hammond GL. Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma. J Endocrinol. 2019 Jan 1; 240(1):27-39. doi: 10.1530/JOE-18-0479. PubMed PMID: 30452386. https://www.ncbi.nlm.nih.gov/pubmed/30452386?dopt=Abstract

4. Kan B, Michalski C, Fu H, Au HHT, Lee K, Marchant EA, Cheng MF, Anderson-Baucum E, Aharoni-Simon M, Tilley P, Mirmira RG, Ross CJ, Luciani DS, Jan E, Lavoie PM. Cellular metabolism constrains innate immune responses in early human ontogeny. Nat Commun. 2018 Nov 16; 9(1):4822. doi: 10.1038/s41467-018-07215-9. PubMed PMID: 30446641; PubMed Central PMCID: PMC6240060. https://www.ncbi.nlm.nih.gov/pubmed/30446641?dopt=Abstract

5. Shimazu-Kuwahara S, Kanemaru Y, Harada N, Ikeguchi E, Ueda Y, Yamane S, Murata Y, Yasoda A, Kieffer TJ, Inagaki N. Glucose-dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance but deteriorated bone loss in ovariectomized mice. J Diabetes Investig. 2018 Nov 19. doi:10.1111/jdi.12978. [Epub ahead of print] PubMed PMID: 30451382. https://www.ncbi.nlm.nih.gov/pubmed/30451382?dopt=Abstract

6.Werth AJ, Lillie MA, Piscitelli MA, Vogl AW, Shadwick RE. Slick, stretchy fascia underlies the sliding tongue of rorquals. Anat Rec (Hoboken). 2018 Nov 17.doi: 10.1002/ar.24035. [Epub ahead of print] PubMed PMID: 30447133. https://www.ncbi.nlm.nih.gov/pubmed/30447133?dopt=Abstract

7. Fujiwara S, Hoshizaki M, Ichida Y, Lex D, Kuroda E, Ishii KJ, Magi S, Okada M, Takao H, Gandou M, Imai H, Hara R, Herzog H, Yoshimura A, Okamura H, Penninger JM, Slutsky AS, Uhlig S, Kuba K, Imai Y. Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection. Nat Microbiol. 2018 Nov 19. doi: 10.1038/s41564-018-0289-1. [Epub ahead of print] PubMed PMID: 30455472. https://www.ncbi.nlm.nih.gov/pubmed/30455472?dopt=Abstract

Nov. 12, Pubcrawler Hits:

1. Kerr CH, Wang QS, Moon KM, Keatings K, Allan DW, Foster LJ, Jan E. IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection. Nucleic Acids Res. 2018 Nov 10. doi: 10.1093/nar/gky1121. [Epub ahead of print] PubMed PMID: 30418631. https://www.ncbi.nlm.nih.gov/pubmed/30418631?report=&dispmax=200&tool=PubCrawler_1.4

2. Roston TM, Haji-Ghassemi O, LaPage MJ, Batra AS, Bar-Cohen Y, Anderson C, Lau YR, Maginot K, Gebauer RA, Etheridge SP, Potts JE, Van Petegem F, Sanatani S. Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry. PLoS One. 2018 Nov 7; 13(11):e0205925. doi: 10.1371/journal.pone.0205925. eCollection 2018. PubMed PMID: 30403697; PubMed Central PMCID: PMC6221297. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205925

Nov. 05, Pubcrawler Hits:

1. Marshall NC, Klein T, Thejoe M, von Krosigk N, Kizhakkedathu J, Finlay BB, Overall CM. Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation. J Proteome Res. 2018 Oct 29. doi: 10.1021/acs.jproteome.8b00675. [Epub ahead of print] PubMed PMID: 30371095. https://www.ncbi.nlm.nih.gov/pubmed/30371095

2. Mei Y, Yu K, Lo JCY, Takeuchi LE, Hadjesfandiari N, Yazdani-Ahmadabadi H, Brooks DE, Lange D, Kizhakkedathu JN. Polymer-Nanoparticle Interaction as a Design Principle in the Development of a Durable Ultrathin Universal Binary Antibiofilm Coating with Long-Term Activity. ACS Nano. 2018 Oct 29. doi: 10.1021/acsnano.8b05512. [Epub ahead of print] PubMed PMID: 30354054. https://www.ncbi.nlm.nih.gov/pubmed/30354054

3. McDiarmid TA, Au V, Loewen AD, Liang J, Mizumoto K, Moerman DG, Rankin CH. CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance. Dis Model Mech. 2018 Oct 25. pii: dmm.036517. doi: 10.1242/dmm.036517. [Epub ahead of print] PubMed PMID: 30361258. http://dmm.biologists.org/content/11/12/dmm036517

4. Tham DKL, Moukhles H. Towards a better understanding of AQP4's role in astrocytic process extension: An Editorial for 'Involvement of aquaporin-4 in laminin-enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and a-syntrophin in aquaporin-4 expression' on doi:10.1111/jnc.14548. J Neurochem. 2018 Oct 30. doi: 10.1111/jnc.14590. [Epub ahead of print] PubMed PMID: 30378126. https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.14590

5. Redfield RJ, Soucy SM. Evolution of Bacterial Gene Transfer Agents. Front Microbiol. 2018 Oct 25; 9:2527. doi: 10.3389/fmicb.2018.02527. eCollection 2018. PubMed PMID: 30410473; PubMed Central PMCID: PMC6209664. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209664/

6. Alexander JAN, Chatterjee SS, Hamilton SM, Eltis LD, Chambers HF, Strynadka NCJ. Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. J Biol Chem. 2018 Oct 26. pii: jbc.RA118.004952. doi: 10.1074/jbc.RA118.004952. [Epub ahead of print] PubMed PMID: 30366985. https://www.ncbi.nlm.nih.gov/pubmed/30366985?report=&dispmax=200&tool=PubCrawler_1.4

7. Lam VYY, Raineki C, Wang LY, Chiu M, Lee G, Ellis L, Yu W, Weinberg J. Role of corticosterone in anxiety- and depressive-like behavior and HPA regulation following prenatal alcohol exposure. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Oct 24; 90:1-15. doi: 10.1016/j.pnpbp.2018.10.008. [Epub ahead of print]PubMed PMID: 30367959. https://www.sciencedirect.com/science/article/pii/S0278584618304172?via%3Dihub

Oct. 29, Pubcrawler Hits:

1. Lemieux MJ, Denault JB, Overall CM. Highlight: Frontiers in Proteolysis. Biol Chem. 2018 Oct 26. pii: /j/bchm.ahead-of-print/hsz-2018-0401/hsz-2018-0401.xml. doi: 10.1515/hsz-2018-0401. [Epub ahead of print] PubMed PMID: 30352023. https://www.ncbi.nlm.nih.gov/pubmed/30352023?dopt=Abstract

2. Wang K, Holt C, Lu J, Brohus M, Larsen KT, Overgaard MT, Wimmer R, Van Petegem F. Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc Natl Acad Sci US A. 2018 Oct 22. pii: 201808733. doi: 10.1073/pnas.1808733115. [Epub ahead of print] PubMed PMID: 30348784. https://www.ncbi.nlm.nih.gov/pubmed/30348784?dopt=Abstract

Oct. 22, Pubcrawler Hits:

1. Thompson E, Eldstrom J, Westhoff M, McAfee D, Fedida D. The I(Ks) Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry. Biophys J. 2018 Sep 27. pii: S0006-3495(18)31072-5. doi: 10.1016/j.bpj.2018.09.018. [Epub ahead of print] PubMed PMID: 30314657. https://www.ncbi.nlm.nih.gov/pubmed/30314657?dopt=Abstract

2. Molday LL, Cheng CL, Molday RS. Cell-Specific Markers for the Identification of Retinal Cells and Subcellular Organelles by Immunofluorescence Microscopy. Methods Mol Biol. 2019;1834:293-310. doi: 10.1007/978-1-4939-8669-9_19. PubMed PMID: 30324451. https://www.ncbi.nlm.nih.gov/pubmed/30324451?dopt=Abstract

3. Adams A, Sriram A, Vogl AW. Internalization of intact intercellular junctions in the testis by clathrin/actin-mediated endocytic structures: Tubulobulbar complexes. Anat Rec (Hoboken). 2018 Oct 12. doi: 10.1002/ar.23963. [Epub ahead of print] PubMed PMID: 30312540. https://www.ncbi.nlm.nih.gov/pubmed/30312540?dopt=Abstract

4. Moukarzel S, Dyer RA, Garcia C, Wiedeman AM, Boyce G, Weinberg J, Keller BO, Elango R, Innis SM. Milk Fat Globule Membrane Supplementation in Formula-fed Rat Pups Improves Reflex Development and May Alter Brain Lipid Composition. Sci Rep. 2018 Oct 15;8(1):15277. doi: 10.1038/s41598-018-33603-8. PubMed PMID: 30323309. https://www.ncbi.nlm.nih.gov/pubmed/30323309?dopt=Abstract

Oct. 15, Pubcrawler Hits:

1. Jaeger AH, Stanley M, Weiss ZF, Musso PY, Chan RC, Zhang H, Feldman-Kiss D, Gordon MD. A complex peripheral code for salt taste in Drosophila. Elife. 2018 Oct 11;7. pii: e37167. doi: 10.7554/eLife.37167. PubMed PMID: 30307393. https://www.ncbi.nlm.nih.gov/pubmed/30307393?dopt=Abstract

2. Nayak A, Kim DY, Trnka MJ, Kerr CH, Lidsky PV, Stanley DJ, Rivera BM, Li KH, Burlingame AL, Jan E, Frydman J, Gross JD, Andino R. A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability. Cell Host Microbe. 2018 Oct 10;24(4):542-557.e9. doi: 10.1016/j.chom.2018.09.006. PubMed PMID: 30308158. https://www.ncbi.nlm.nih.gov/pubmed/30308158?dopt=Abstract

3. Myette-Côté É, Durrer C, Neudorf H, Bammert TD, Botezelli JD, Johnson JD, DeSouza CA, Little JP. Short-term low-carbohydrate high-fat diet with or without post-meal walks on glycemic control and inflammation in type 2 diabetes: A randomized trial. Am J Physiol Regul Integr Comp Physiol. 2018 Oct 10. doi: 10.1152/ajpregu.00240.2018. [Epub ahead of print] PubMed PMID: 30303707. https://www.ncbi.nlm.nih.gov/pubmed/30303707?dopt=Abstract

4. Neumann UH, Kwon MM, Baker RK, Kieffer TJ. Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice. Am J Physiol Endocrinol Metab. 2018 Oct 9. doi: 10.1152/ajpendo.00159.2018. [Epub ahead of print] PubMed PMID: 30300012. https://www.ncbi.nlm.nih.gov/pubmed/30300012?dopt=Abstract

Oct. 08, Pubcrawler Hits:

1. Mallia-Milanes B, Dufour A, Philp C, Solis N, Klein T, Fischer M, Bolton CE, Shapiro SD, Overall CM, Johnson SR. TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 4. doi: 10.1152/ajplung.00175.2018. [Epub ahead of print] PubMed PMID: 30284925. https://www.ncbi.nlm.nih.gov/pubmed/30284925

2. Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H. Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate. Commun Biol. 2018 Aug 17;1:120. doi: 10.1038/s42003-018-0121-8. eCollection 2018. PubMed PMID: 30272000. https://www.ncbi.nlm.nih.gov/pubmed/30272000

3. Adam N, Trumm M, Smith VC, MacGillivray RTA, Panak PJ. Incorporation of transuranium elements: coordination of Cm(iii) to human serum transferrin. Dalton Trans. 2018 Oct 1. doi: 10.1039/c8dt02915f. [Epub ahead of print]. PubMed PMID: 30270390. https://www.ncbi.nlm.nih.gov/pubmed/30270390

Oct. 01, Pubcrawler Hits:

1. Wilhelm RC, Singh R, Eltis LD, Mohn WW. Bacterial contributions to delignification and lignocellulose degradation in forest soils with metagenomic and quantitative stable isotope probing. ISME J. 2018 Sep 26. doi: 10.1038/s41396-018-0279-6. [Epub ahead of print] PubMed PMID: 30258172. https://www.ncbi.nlm.nih.gov/pubmed/30258172?dopt=Abstract

Sep. 24, Pubcrawler Hits:

1. Boraschi-Diaz I, Mort JS, Brömme D, Senis YA, Mazharian A, Komarova SV. Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation. Bone. 2018 Sep 12;117:23-30. doi: 10.1016/j.bone.2018.09.006. [Epub ahead of print] PubMed PMID:30217615. https://www.ncbi.nlm.nih.gov/pubmed/30217615?dopt=Abstract

2. Kenward PA, Simister RL, Morgan-Lang C, Finke N, Sturm A, Hallam SJ, Crowe SA. Recovering cellular biomass from fluids using chemical flocculation. Environ Microbiol Rep. 2018 Sep 19. doi: 10.1111/1758-2229.12690. [Epub ahead of print]PubMed PMID: 30230256. https://www.ncbi.nlm.nih.gov/pubmed/30230256?dopt=Abstract

3. Leach Bennett J, Devine DV. Risk-based decision making in transfusion medicine. Vox Sang. 2018 Sep 19. doi: 10.1111/vox.12708. [Epub ahead of print] Review. PubMed PMID: 30232803. https://www.ncbi.nlm.nih.gov/pubmed/30232803?dopt=Abstract

4. Martin BJE, Chruscicki AT, Howe LJ. Transcription Promotes the Interaction of the FAcilitates Chromatin Transactions (FACT) Complex with Nucleosomes in Saccharomyces cerevisiae. Genetics. 2018 Sep 20. pii: genetics.301349.2018. doi:  10.1534/genetics.118.301349. [Epub ahead of print] PubMed PMID: 30237209. https://www.ncbi.nlm.nih.gov/pubmed/30237209?dopt=Abstract

Sep. 17, Pubcrawler Hits:

1. Pirapaharan DC, Søe K, Panwar P, Madsen JS, Bergmann ML, Overgaard M, Brömme D, Delaisse JM. A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture. Calcif Tissue Int. 2018 Sep 7. doi: 10.1007/s00223-018-0472-7. [Epub ahead of print] PubMed PMID: 30194476. https://www.ncbi.nlm.nih.gov/pubmed/30194476?dopt=Abstract

2. Pancaroglu R, Van Petegem F. Calcium Channelopathies: Structural Insights into Disorders of the Muscle Excitation-Contraction Complex. Annu Rev Genet. 2018 Sep 12. doi: 10.1146/annurev-genet-120417-031311. [Epub ahead of print] PubMed PMID: 30208288.  https://www.ncbi.nlm.nih.gov/pubmed/30208288?dopt=Abstract

Sep. 10, Pubcrawler Hits:

1. von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA. Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial. Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28. PubMed PMID: 30177038.   https://www.ncbi.nlm.nih.gov/pubmed/30177038?dopt=Abstract

2. Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E. Screening of red blood cells for extracellular vesicle content as a product quality indicator. Transfusion. 2018 Aug 31. doi: 10.1111/trf.14782. [Epub ahead of print] PubMed PMID: 30168148. https://www.ncbi.nlm.nih.gov/pubmed/30168148?dopt=Abstract

Sep. 3, Pubcrawler Hits:

1. Dalal K, Ban F, Li H, Morin H, Roshan-Moniri M, Tam KJ, Shepherd A, Sharma A, Peacock J, Carlson ML, LeBlanc E, Perez C, Duong F, Ong CJ, Rennie PS, Cherkasov A. Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer. Cancer Lett. 2018 Aug 27; 437:35-43. doi: 10.1016/j.canlet.2018.08.016. [Epub ahead of print] PubMed PMID: 30165195.

Aug 27, Pubcrawler Hits:

1. Lei CL, Kellard JA, Hara M, Johnson JD, Rodriguez B, Briant LJB. Beta-cell hubs maintain Ca(2+) oscillations in human and mouse islet simulations. Islets. 2018;10(4):151-167. doi: 10.1080/19382014.2018.1493316. PubMed PMID: 30142036. https://www.ncbi.nlm.nih.gov/pubmed/30142036?dopt=Abstract

2. Kalathottukaren MT, Creagh AL, Abbina S, Lu G, Karbarz MJ, Pandey A, Conley PB, Kizhakkedathu JN, Haynes C. Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors. Blood Adv. 2018 Aug 28;2(16):2104-2114. doi: 10.1182/bloodadvances.2016003616. PubMed PMID: 30135185. https://www.ncbi.nlm.nih.gov/pubmed/30135185?dopt=Abstract

3. Meneksedag-Erol D, Kizhakkedathu JN, Tang T, Uludağ H. Molecular Dynamics Simulations on Nucleic Acid Binding Polymers Designed To Arrest Thrombosis. ACS Appl Mater Interfaces. 2018 Aug 20. doi: 10.1021/acsami.8b09914. [Epub ahead of print] PubMed PMID: 30085650.  https://www.ncbi.nlm.nih.gov/pubmed/30085650?dopt=Abstract

4. Brind'Amour J, Kobayashi H, Richard Albert J, Shirane K, Sakashita A, Kamio A, Bogutz A, Koike T, Karimi MM, Lefebvre L, Kono T, Lorincz MC. LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation. Nat Commun. 2018 Aug 20;9(1):3331. doi: 10.1038/s41467-018-05841-x. PubMed PMID: 30127397; PubMed Central PMCID: PMC6102241.  https://www.ncbi.nlm.nih.gov/pubmed/30127397?dopt=Abstract

5. Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Snyder M, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project. J Proteome Res. 2018 Aug 23. doi: 10.1021/acs.jproteome.8b00441. [Epub ahead of print] PubMed PMID: 30099871. https://www.ncbi.nlm.nih.gov/pubmed/30099871?dopt=Abstract

6. Blaukopf M, Worrall L, Kosma P, Strynadka NCJ, Withers SG. Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex. Structure. 2018 Jul 23. pii: S0969-2126(18)30247-8. doi: 10.1016/j.str.2018.07.001. [Epub ahead of print] PubMed PMID: 30122450. https://www.ncbi.nlm.nih.gov/pubmed/30122450?dopt=Abstract

Aug 20, Pubcrawler Hits:

1. Carlson ML, Young JW, Zhao Z, Fabre L, Jun D, Li J, Li J, Dhupar HS, Wason I, Mills AT, Beatty JT, Klassen JS, Rouiller I, Duong F. The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution. Elife. 2018  Aug 15;7. pii: e34085. doi: 10.7554/eLife.34085. PubMed PMID: 30109849; PubMed Central PMCID: PMC6093710. https://www.ncbi.nlm.nih.gov/pubmed/30109849?dopt=Abstract

2. Bogutz AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, Gu T, Gertsenstein M, Nagy A, Lefebvre L. Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. PLoS Genet. 2018 Aug 10;14(8):e1007587. doi: 10.1371/journal.pgen.1007587. [Epub ahead of print] PubMed PMID: 30096149. https://www.ncbi.nlm.nih.gov/pubmed/30096149?dopt=Abstract

3. Bergeron JRC, Brockerman JA, Vuckovic M, Deng W, Okon M, Finlay BB, McIntosh LP, Strynadka NCJ. Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. Protein Sci. 2018 Aug 10. doi: 10.1002/pro.3447.[Epub ahead of print] PubMed PMID: 30095200.https://www.ncbi.nlm.nih.gov/pubmed/30095200?dopt=Abstract

4. Holman PJ, Ellis L, Morgan E, Weinberg J. Prenatal alcohol exposure disrupts male adolescent social behavior and oxytocin receptor binding in rodents. Horm Behav. 2018 Aug 16;105:115-127. doi: 10.1016/j.yhbeh.2018.08.004. [Epub ahead of print] PubMed PMID: 30110605. https://www.ncbi.nlm.nih.gov/pubmed/30110605?dopt=Abstract

5. Nassar R, Wong E, Bui JM, Yip CK, Li H, Gsponer J, Lamour G. Mechanical Anisotropy in GNNQQNY Amyloid Crystals. J Phys Chem Lett. 2018 Aug 15:4901-4909. doi: 10.1021/acs.jpclett.8b02027. [Epub ahead of print] PubMed PMID: 30102541. https://www.ncbi.nlm.nih.gov/pubmed/30102541?dopt=Abstract

Aug 13, Pubcrawler Hits:

1. Zatmári D, Xue B, Kannan B, Burtnick LD, Bugyi B, Nyitrai M, Robinson RC. ATP competes with PIP2 for binding to gelsolin. PLoS One. 2018 Aug 7;13(8):e0201826. doi: 10.1371/journal.pone.0201826. eCollection 2018. PubMed PMID: 30086165. https://www.ncbi.nlm.nih.gov/pubmed/30086165?dopt=Abstract

2. Liu MM, Boinett CJ, Chan ACK, Parkhill J, Murphy MEP, Gaynor EC. Investigating the Campylobacter jejuni Transcriptional Response to Host Intestinal Extracts Reveals the Involvement of a Widely Conserved Iron Uptake System. MBio. 2018 Aug 7; 9(4). pii: e01347-18. doi: 10.1128/mBio.01347-18. PubMed PMID: 30087169. https://www.ncbi.nlm.nih.gov/pubmed/30087169?dopt=Abstract

3. Wang C, Fung G, Deng H, Jagdeo J, Mohamud Y, Xue YC, Jan E, Hirota JA, Luo H. NLRP3 deficiency exacerbates enterovirus infection in mice. FASEB J. 2018 Aug 6:fj201800301RRR. doi: 10.1096/fj.201800301RRR. [Epub ahead of print] PubMed PMID: 30080445. https://www.ncbi.nlm.nih.gov/pubmed/30080445?dopt=Abstract

4. Fukuda Y, Matsusaki T, Tse KM, Mizohata E, Murphy MEP, Inoue T. Crystallographic study of dioxygen chemistry in a copper-containing nitrite reductase from Geobacillus thermodenitrificans. Acta Crystallogr D Struct Biol. 2018 Aug 1;74(Pt 8):769-777. doi: 10.1107/S2059798318010082. Epub 2018 Jul 24. PubMed PMID: 30082512. https://www.ncbi.nlm.nih.gov/pubmed/30082512?dopt=Abstract

Aug 06, Pubcrawler Hits:

1. Chen X, Shibata AC, Hendi A, Kurashina M, Fortes E, Weilinger NL, MacVicar BA, Murakoshi H, Mizumoto K. Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans. Elife. 2018 Jul 31;7. pii: e38801. doi: 10.7554/eLife.38801. PubMed PMID: 30063210. https://www.ncbi.nlm.nih.gov/pubmed/30063210?dopt=Abstract

2. Pryzdial ELG, Lee FMH, Lin BH, Carter RLR, Tegegn TZ, Belletrutti MJ. Blood coagulation dissected. Transfus Apher Sci. 2018 Jul 20. pii: S1473-0502(18)30281-7. doi: 10.1016/j.transci.2018.07.003. [Epub ahead of print] Review. PubMed PMID: 30049564. https://www.ncbi.nlm.nih.gov/pubmed/30049564?dopt=Abstract

3. Neuenschwander R, Hookenson K, Brain U, Grunau RE, Devlin AM, Weinberg J, Diamond A, Oberlander TF. Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls. Dev Psychopathol. 2018 Aug;30(3):953-969. doi: 10.1017/S095457941800041X. PubMed PMID: 30068413. https://www.ncbi.nlm.nih.gov/pubmed/30068413?dopt=Abstract

Jul 30, Pubcrawler Hits:

1. Chen S, Zaifman J, Kulkarni JA, Zhigaltsev IV, Tam YK, Ciufolini MA, Tam YYC, Cullis PR. Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids. J Control Release.2018 Jul 17;286:46-54. doi: 10.1016/j.jconrel.2018.07.026. [Epub ahead of print] PubMed PMID: 30026080. https://www.ncbi.nlm.nih.gov/pubmed/30026080?dopt=Abstract

2. Thompson E, Eldstrom J, Fedida D. Single channel kinetic analysis of the cAMP effect on I(Ks) mutants, S209F and S27D/S92D. Channels (Austin). 2018 Jul 20.doi: 10.1080/19336950.2018.1499369. [Epub ahead of print] PubMed PMID: 30027808. https://www.ncbi.nlm.nih.gov/pubmed/30027808?dopt=Abstract

3. Volkers G, Lizak C, Niesser J, Rosell FI, Preidl J, Gnanapragassam VS, Horstkorte R, Rademann J, Strynadka NCJ. Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family. ACS Chem Biol. 2018 Jul 26. doi: 10.1021/acschembio.8b00478. [Epub ahead of print] PubMed PMID: 30015474. https://www.ncbi.nlm.nih.gov/pubmed/30015474?dopt=Abstract

4. Dornan GL, Dalwadi U, Hamelin DJ, Hoffmann RM, Yip CK, Burke JE. Probing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex. J Mol Biol. 2018 Jul 18. pii: S0022-2836(18)30564-3. doi: 10.1016/j.jmb.2018.07.020. [Epub ahead of print] PubMed PMID: 30031006. https://www.ncbi.nlm.nih.gov/pubmed/30031006?dopt=Abstract

Jul 23, Pubcrawler Hits:

1. Gao P, Ho PL, Yan B, Sze KH, Davies J, Kao RYT. Suppression of Staphylococcus aureus virulence by a small-molecule compound. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520. doi: 10.1073/pnas.1720520115. [Epub ahead of print] PubMed PMID: 30012613. https://www.ncbi.nlm.nih.gov/pubmed/30012613?dopt=Abstract

2. Blackmore S, Vriens B, Sorensen M, Power IM, Smith L, Hallam SJ, Mayer KU, Beckie RD. Microbial and geochemical controls on waste rock weathering and drainage quality. Sci Total Environ. 2018 Nov 1;640-641:1004-1014. doi: 10.1016/j.scitotenv.2018.05.374. Epub 2018 Jun 5. PubMed PMID: 30021267. https://www.ncbi.nlm.nih.gov/pubmed/30021267?dopt=Abstract

3. Armstrong Z, Mewis K, Liu F, Morgan-Lang C, Scofield M, Durno E, Chen HM, Mehr K, Withers SG, Hallam SJ. Metagenomics reveals functional synergy and novel polysaccharide utilization loci in the Castor canadensis fecal microbiome. ISMEJ. 2018 Jul 16. doi: 10.1038/s41396-018-0215-9. [Epub ahead of print] PubMed PMID: 30013164. https://www.ncbi.nlm.nih.gov/pubmed/30013164?dopt=Abstract

4. Wang J, Molday LL, Hii T, Coleman JA, Wen T, Andersen JP, Molday RS. Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. Sci Rep. 2018 Jul 17;8(1):10795. doi: 10.1038/s41598-018-29108-z. PubMed PMID: 30018401; PubMed Central PMCID: PMC6050252. https://www.ncbi.nlm.nih.gov/pubmed/30018401?dopt=Abstract

5. McMillan HJ, Telegrafi A, Singleton A, Cho MT, Lelli D, Lynn FC, Griffin J, Asamoah A, Rinne T, Erasmus CE, Koolen DA, Haaxma CA, Keren B, Doummar D, Mignot C, Thompson I, Velsher L, Dehghani M, Vahidi Mehrjardi MY, Maroofian R, Tchan M, Simons C, Christodoulou J, Martín-Hernández E, Guillen Sacoto MJ, Henderson LB, McLaughlin H, Molday LL, Molday RS, Yoon G. Recessive mutations in ATP8A2 cause severe hypotonia, cognitive impairment, hyperkinetic movement disorders and progressive optic atrophy. Orphanet J Rare Dis. 2018 May 31;13(1):86. doi: 10.1186/s13023-018-0825-3. PubMed PMID: 30012219; PubMed Central PMCID: PMC6048855. https://www.ncbi.nlm.nih.gov/pubmed/30012219?dopt=Abstract

6. Richter A, Strauch A, Chao J, Ko M, Av-Gay Y. Screening of preselected libraries targeting Mycobacterium abscessus for drug discovery. Antimicrob Agents Chemother. 2018 Jul 16. pii: AAC.00828-18. doi: 10.1128/AAC.00828-18. [Epub ahead of print] PubMed PMID: 30012760. https://www.ncbi.nlm.nih.gov/pubmed/30012760?dopt=Abstract

Jul 16, Pubcrawler Hits:

1. Ding H, Caza M, Dong Y, Arif AA, Horianopoulos LC, Hu G, Johnson P, Kronstad JW. ATG genes influence the virulence of Cryptococcus neoformans through contributions beyond core autophagy functions. Infect Immun. 2018 Jul 9. pii: IAI.00069-18. doi: 10.1128/IAI.00069-18. [Epub ahead of print] PubMed PMID: 29986893. https://www.ncbi.nlm.nih.gov/pubmed/29986893?dopt=Abstract

2. Lam VYY, Raineki C, Ellis L, Yu W, Weinberg J. Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: Sex- and time-dependent effects. Psychoneuroendocrinology. 2018 Jun 23;97:8-19. doi: 10.1016/j.psyneuen.2018.06.018. [Epub ahead of print] PubMed PMID: 29990678.
https://www.ncbi.nlm.nih.gov/pubmed/29990678?dopt=Abstract

Jul 09, Pubcrawler Hits:

1. Vuillemin A, Horn F, Friese A, Winkel M, Alawi M, Wagner D, Henny C, Orsi WD, Crowe SA, Kallmeyer J. Metabolic potential of microbial communities from ferruginous sediments. Environ Microbiol. 2018 Jul 2. doi: 10.1111/1462-2920.14343. [Epub ahead of print] PubMed PMID: 29968357. https://www.ncbi.nlm.nih.gov/pubmed/29968357

2. Fedida D. Modeling the Hidden Pathways of IKs Channel Activation. Biophys J. 2018 Jul 3;115(1):1-2. doi: 10.1016/j.bpj.2018.05.020. PubMed PMID: 29972801. https://www.ncbi.nlm.nih.gov/pubmed/29972801

Jul 02, Pubcrawler Hits:

1. Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, Franzke CW, Overall CM, Granville DJ. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction. Sci Rep. 2018 Jun 26;8(1):9690. doi: 10.1038/s41598-018-28070-0. PubMed PMID: 29946113. https://www.ncbi.nlm.nih.gov/pubmed/29946113?dopt=Abstract

Jun 25, Pubcrawler Hits:

1. Snieckus V, Hurst T, Nerdinger S, Kautsjah E, Eltis L, Kahlenberg V, Schlapp-Hackl I. Bacterial Catabolism of Biphenyls. Synthesis and Evaluation of Analogues. Chembiochem. 2018 Jun 15. doi: 10.1002/cbic.201800231. [Epub ahead of print] PubMed PMID: 29905982. https://www.ncbi.nlm.nih.gov/pubmed/29905982?dopt=Abstract

2. Richard Albert J, Koike T, Younesy H, Thompson R, Bogutz AB, Karimi MM, Lorincz MC. Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA). BMC Genomics. 2018 Jun 15;19(1):463. doi: 10.1186/s12864-018-4835-2. PubMed PMID: 29907088. https://www.ncbi.nlm.nih.gov/pubmed/29907088?dopt=Abstract

3. van Pel DM, Harada K, Song D, Naus CC, Sin WC. Modelling glioma invasion using 3D bioprinting and scaffold-free 3D culture. J Cell Commun Signal. 2018 Jun 16. doi: 10.1007/s12079-018-0469-z. [Epub ahead of print] PubMed PMID: 29909492. https://www.ncbi.nlm.nih.gov/pubmed/29909492?dopt=Abstract

4. Dufour A, Bellac CL, Eckhard U, Solis N, Klein T, Kappelhoff R, Fortelny N, Jobin P, Rozmus J, Mark J, Pavlidis P, Dive V, Barbour SJ, Overall CM. C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease. Nat Commun. 2018 Jun 20;9(1):2416. doi: 10.1038/s41467-018-04717-4. PubMed PMID: 29925830. https://www.ncbi.nlm.nih.gov/pubmed/29925830?dopt=Abstract

Jun 18, Pubcrawler Hits:

1. Crowe SA, Cox RP, Jones C, Fowle DA, Santibañez-Bustos JF, Ulloa O, Canfield DE. Decrypting the sulfur cycle in oceanic oxygen minimum zones. ISME J. 2018 Jun 7; doi: 10.1038/s41396-018-0149-2. [Epub ahead of print] PubMed PMID: 29884830. https://www.ncbi.nlm.nih.gov/pubmed/29884830?dopt=Abstract

2. Khater IM, Meng F, Wong TH, Nabi IR, Hamarneh G. Super Resolution Network Analysis Defines the Molecular Architecture of Caveolae and Caveolin-1 Scaffolds. Sci Rep. 2018 Jun 13;8(1):9009. doi: 10.1038/s41598-018-27216-4. PubMed PMID: 29899348. https://www.ncbi.nlm.nih.gov/pubmed/29899348?dopt=Abstract

3. Caveney NA, Li FK, Strynadka NC. Enzyme structures of the bacterial peptidoglycan and wall teichoic acid biogenesis pathways. Curr Opin Struct Biol. 2018 Jun 6;53:45-58. doi: 10.1016/j.sbi.2018.05.002. [Epub ahead of print] Review. PubMed PMID: 29885610. https://www.ncbi.nlm.nih.gov/pubmed/29885610?dopt=Abstract

Jun 11, Pubcrawler Hits:

1. Loghmani H, Conway EM. Exploring traditional and non-traditional roles for thrombomodulin. Blood. 2018 Jun 4. pii: blood-2017-12-768994. doi: 10.1182/blood-2017-12-768994. [Epub ahead of print] PubMed PMID: 29866818.   https://www.ncbi.nlm.nih.gov/pubmed/29866818?dopt=Abstract

2. Schubert P, Johnson L, Marks DC, Devine DV. Ultraviolet-Based Pathogen Inactivation Systems: Untangling the Molecular Targets Activated in Platelets. Front Med (Lausanne). 2018 May 7;5:129. doi: 10.3389/fmed.2018.00129. eCollection Review. PubMed PMID: 29868586; PubMed Central PMCID: PMC5949320. https://www.ncbi.nlm.nih.gov/pubmed/29868586?dopt=Abstract

3. Heinkel F, Shen L, Richard-Greenblatt M, Okon M, Bui JM, Gee CL, Gay LM, Alber T, Av-Gay Y, Gsponer J, McIntosh LP. Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747. Structure. 2018 May 17. pii: S0969-2126(18)30164-3. doi: 10.1016/j.str.2018.04.018. [Epub ahead of print] PubMed PMID: 29861345. https://www.ncbi.nlm.nih.gov/pubmed/29861345?dopt=Abstract

Jun 2, Pubcrawler Hits:

1. Garces F, Jiang K, Molday LL, Stöhr H, Weber BH, Lyons CJ, Maberley D, Molday RS. Correlating the Expression and Functional Activity of ABCA4 Disease Variants With the Phenotype of Patients With Stargardt Disease. Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2305-2315. doi: 10.1167/iovs.17-23364. PubMed PMID: 29847635; PubMed Central PMCID: PMC5937799 https://www.ncbi.nlm.nih.gov/pubmed/29847635?dopt=Abstract

2. Grek CL, Sheng Z, Naus CC, Sin WC, Gourdie RG, Ghatnekar GG. Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics. Curr Opin Pharmacol. 2018 May 24;41:79-88. doi: 10.1016/j.coph.2018.05.002. [Epub ahead of print] Review. PubMed PMID: 29803991. https://www.ncbi.nlm.nih.gov/pubmed/29803991?dopt=Abstract 

May 28, Pubcrawler Hits:

1. Tharmarajah G, Eckhard U, Jain F, Marino G, Prudova A, Urtatiz O, Fuchs H, Hrabe de Angelis M, Overall CM, Van Raamsdonk CD. Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase. Pigment Cell Melanoma Res. 2018 May 21. doi: 10.1111/pcmr.12711. [Epub ahead of print] PubMed PMID: 29781574. https://www.ncbi.nlm.nih.gov/pubmed/29781574?dopt=Abstract

May 21, Pubcrawler Hits:

1. Siren EMJ, Chapanian R, Constantinescu I, Brooks DE, Kizhakkedathu JN. Oncotically Driven Control over Glycocalyx Dimension for Cell Surface Engineering and Protein Binding in the Longitudinal Direction. Sci Rep. 2018 May 15; 8(1):7581. doi: 10.1038/s41598-018-25870-2. PubMed PMID: 29765073. https://www.ncbi.nlm.nih.gov/pubmed/29765073?dopt=Abstract

2. Han B, Guan Q, Chafeeva I, Mendelson AA, Roza GD, Liggins R, Kizhakkedathu JN, Du C. Peritoneal and Systemic Responses of Obese Type II Diabetic Rats to Chronic Exposure to a Hyperbranched Polyglycerol-based Dialysis Solution. Basic Clin Pharmacol Toxicol. 2018 May 12. doi: 10.1111/bcpt.13038. [Epub ahead of print] PubMed PMID: 29753311. https://www.ncbi.nlm.nih.gov/pubmed/29753311?dopt=Abstract

3. Pryjma M, Burian J, Thompson CJ. Rifabutin acts in synergy and is bactericidal with frontline Mycobacterium abscessus antibiotics clarithromycin and tigecycline, suggesting a potent treatment combination. Antimicrob Agents Chemother. 2018 May 14. pii: AAC.00283-18. doi: 10.1128/AAC.00283-18. [Epub ahead of print] PubMed PMID: 29760147. https://www.ncbi.nlm.nih.gov/pubmed/29760147?dopt=Abstract

May 14, Pubcrawler Hits:

1. Li RC, Lin CC, Ren X, Wu JS, Molday LL, Molday RS, Yau KW. Ca(2+)-activated Cl current predominates in threshold response of mouse olfactory receptor neurons. Proc Natl Acad Sci U S A. 2018 May 7. pii: 201803443. doi: 10.1073/pnas.1803443115. [Epub ahead of print] PubMed PMID: 29735665. https://www.ncbi.nlm.nih.gov/pubmed/29735665?dopt=Abstract

2. Dhanda AS, Lulic KT, Vogl AW, Mc Gee MM, Chiu RH, Guttman JA. Listeria membrane protrusion collapse: Requirement of Cyclophilin A for Listeria cell-to-cell spreading. J Infect Dis. 2018 May 4. doi: 10.1093/infdis/jiy255. [Epub ahead of print] PubMed PMID: 29733369. https://www.ncbi.nlm.nih.gov/pubmed/29733369?dopt=Abstract

3. Bodnar TS, Raineki C, Wertelecki W, Yevtushok L, Plotka L, Zymak-Zakutnya N, Honerkamp-Smith G, Wells A, Rolland M, Woodward TS, Coles CD, Kable JA, Chambers CD, Weinberg J. Altered maternal immune networks are associated with adverse child neurodevelopment: Impact of alcohol consumption during pregnancy. Brain Behav Immun. 2018 May 5. pii: S0889-1591(18)30175-2. doi: 10.1016/j.bbi.2018.05.004. [Epub ahead of print] PubMed PMID: 29738852. https://www.ncbi.nlm.nih.gov/pubmed/29738852?dopt=Abstract

May 7, Pubcrawler Hits:

1. Daniel E, Daudé M, Kolotuev I, Charish K, Auld V, Le Borgne R. Coordination of Septate Junctions Assembly and Completion of Cytokinesis in Proliferative Epithelial Tissues. Curr Biol. 2018 Apr 20. pii: S0960-9822(18)30363-4. doi: 10.1016/j.cub.2018.03.034. Epub ahead of print] PubMed PMID: 29706514. https://www.ncbi.nlm.nih.gov/pubmed/29706514?dopt=Abstract

2. Laqua K, Klemm M, Richard-Greenblatt M, Richter A, Liebe L, Huang T, Lin S, Guardia A, Pérez-Herran E, Ballell L, Av-Gay Y, Imming P. Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides. Bioorg Med Chem. 2018 Apr 22. pii: S0968-0896(18)30460-7. doi: 10.1016/j.bmc.2018.04.045. [Epub ahead of print] PubMed PMID: 29706526. https://www.ncbi.nlm.nih.gov/pubmed/29706526?dopt=Abstract 

Apr 30 Pubcrawler Hits:

1. Balaton BP, Dixon-McDougall T, Peeters SB, Brown CJ. The eXceptional nature of the X chromosome. Hum Mol Genet. 2018 Apr 26. doi: 10.1093/hmg/ddy148. [Epub ahead of print] PubMed PMID: 29701779. https://www.ncbi.nlm.nih.gov/pubmed/29701779?dopt=Abstract

2. Kulkarni JA, Cullis PR, van der Meel R. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility. Nucleic Acid Ther. 2018 Apr 23. doi: 10.1089/nat.2018.0721. [Epub ahead of print] PubMed PMID: 29683383. https://www.ncbi.nlm.nih.gov/pubmed/29683383?dopt=Abstract

3. Wang JC, Bolger-Munro M, Gold MR. Visualizing the Actin and Microtubule Cytoskeletons at the B-cell Immune Synapse Using Stimulated Emission Depletion (STED) Microscopy. J Vis Exp. 2018 Apr 9;(134). doi: 10.3791/57028. PubMed PMID: 29683438. https://www.ncbi.nlm.nih.gov/pubmed/29683438?dopt=Abstract

4. Lee-Sayer SSM, Dougan MN, Cooper J, Sanderson L, Dosanjh M, Maxwell CA, Johnson P. CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment. PLoS One. 2018 Apr 23;13(4):e0196011. doi: 10.1371/journal.pone.0196011. eCollection 2018. PubMed PMID: 29684048. https://www.ncbi.nlm.nih.gov/pubmed/29684048?dopt=Abstract

5. Stahl M, Tremblay S, Montero M, Vogl W, Xia L, Jacobson K, Menendez A, Vallance BA. The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion. Am J Physiol Gastrointest Liver Physiol. 2018 Apr 26. doi: 10.1152/ajpgi.00264.2017. [Epub ahead of print] PubMed PMID: 29698056. https://www.ncbi.nlm.nih.gov/pubmed/29698056?dopt=Abstract

6. Lillie MA, Vogl AW, Raverty S, Haulena M, McLellan WA, Stenson GB, Shadwick RE. The caval sphincter in cetaceans and its predicted role in controlling venous flow during a dive. J Exp Biol. 2018 Apr 19. pii: jeb.177212. doi: 10.1242/jeb.177212. [Epub ahead of print] PubMed PMID: 29674378. https://www.ncbi.nlm.nih.gov/pubmed/29674378?dopt=Abstract

Apr 23 Pubcrawler Hits:

1. Louca S, Polz MF, Mazel F, Albright MBN, Huber JA, O'Connor MI, Ackermann M, Hahn AS, Srivastava DS, Crowe SA, Doebeli M, Parfrey LW. Function and functional redundancy in microbial systems. Nat Ecol Evol. 2018 Apr 16. doi:10.1038/s41559-018-0519-1. [Epub ahead of print] Review. PubMed PMID: 29662222. https://www.ncbi.nlm.nih.gov/pubmed/29662222?dopt=Abstract

2. Irwin NAT, Martin BJE, Young BP, Browne MJG, Flaus A, Loewen CJR, Keeling PJ, Howe LJ. Viral proteins as a potential driver of histone depletion in dinoflagellates. Nat Commun. 2018 Apr 18; 9(1):1535. doi: 10.1038/s41467-018-03993-4. PubMed PMID: 29670105; PubMed Central PMCID: PMC5906630. https://www.ncbi.nlm.nih.gov/pubmed/29670105?dopt=Abstract

Apr 16 Pubcrawler Hits:

1. Kulkarni JA, Darjuan MM, Mercer JE, Chen S, van der Meel R, Thewalt JL, Tam YYC, Cullis PR. On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA. ACS Nano. 2018 Apr 6. doi: 10.1021/acsnano.8b01516. [Epub ahead of print] PubMed PMID: 29614232. https://www.ncbi.nlm.nih.gov/pubmed/29614232?dopt=Abstract

2. Page MM, Johnson JD. Mild Suppression of Hyperinsulinemia to Treat Obesity and Insulin Resistance. Trends in Endocrinology & Metabolism. 2018 Apr 15. DOI: https://doi.org/10.1016/j.tem.2018.03.018. http://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(18)30073-0

3. Dhanda AS, Vogl AW, Albraiki SE, Otey CA, Beck MR, Guttman JA. Palladin Compensates for the Arp2/3 Complex and Supports Actin Structures during Listeria Infections. MBio. 2018 Apr 10;9(2). pii: e02259-17. doi: 10.1128/mBio.02259-17. PubMed PMID: 29636431; PubMed Central PMCID: PMC5893873. https://www.ncbi.nlm.nih.gov/pubmed/29636431?dopt=Abstract

Apr 9 Pubcrawler Hits:

1. Abramyan J, Richman JM. Craniofacial development: discoveries made in the chicken embryo. Int J Dev Biol. 2018;62(1-2-3):97-107. doi: 10.1387/ijdb.170321ja. PubMed PMID: 29616744. https://www.ncbi.nlm.nih.gov/pubmed/29616744?dopt=Abstract

Apr 2 Pubcrawler Hits:

1. Crowe AM, Workman SD, Watanabe N, Worrall LJ, Strynadka NCJ, Eltis LD. IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase. Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 201717015. doi:10.1073/pnas.1717015115. [Epub ahead of print] PubMed PMID: 29581275. https://www.ncbi.nlm.nih.gov/pubmed

2. Adams WK, D'souza AM, Sussman JL, Kaur S, Kieffer TJ, Winstanley CA. Enhanced amphetamine-induced motor impulsivity and mild attentional impairment in theleptin-deficient rat model of obesity. Physiol Behav. 2018 Mar 27. pii:S0031-9384(18)30150-1. doi: 10.1016/j.physbeh.2018.03.027. [Epub ahead of print] PubMed PMID: 29601831. https://www.ncbi.nlm.nih.gov/pubmed/29601831?dopt=Abstract

3. Mafi A, Abbina S, Kalathottukaren MT, Morrissey JH, Haynes C, Kizhakkedathu JN, Pfaendtner J, Chou KC. Design of Polyphosphate Inhibitors: A Molecular Dynamics Investigation on Polyethylene Glycol-Linked Cationic Binding Groups. Biomacromolecules. 2018 Mar 23. doi: 10.1021/acs.biomac.8b00327. [Epub ahead of print] PubMed PMID: 29539260. https://www.ncbi.nlm.nih.gov/pubmed/29539260?dopt=Abstract

4. Wiesenfahrt T, Duanmu J, Snider F, Moerman D, Au V, Li-Leger E, Flibotte S, Parker DM, Marshall CJ, Osborne Nishimura E, Mains PE, McGhee JD. A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2. G3 (Bethesda). 2018 Mar 28. pii: g3.200079.2018. doi: 10.1534/g3.118.200079. [Epub ahead of print] PubMed PMID: 29593072. https://www.ncbi.nlm.nih.gov/pubmed/29593072?dopt=Abstract

5. Wang JSH, Freitas-Andrade M, Bechberger JF, Naus C, Yeung KK, Whitehead SN. MALDI IMS of Intraperitoneally Injected Danegaptide (ZP1609) for Treatment of Stroke-Reperfusion Injury in Mice. Rapid Commun Mass Spectrom. 2018 Mar 25. doi: 10.1002/rcm.8115. [Epub ahead of print] PubMed PMID: 29575411. https://www.ncbi.nlm.nih.gov/pubmed/29575411?dopt=Abstract

6. King SL, Goth CK, Eckhard U, Joshi HJ, Haue AD, Vakhrushev S, Schjoldager K, Overall CM, Wandall HH. TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation. J Biol Chem. 2018 Mar 28. pii: bc.RA118.001978. doi: 10.1074/jbc.RA118.001978. [Epub ahead of print]PubMed PMID: 29593093. https://www.ncbi.nlm.nih.gov/pubmed/29593093?dopt=Abstract

7. Kang N, Guo Q, Islamzada E, Ma H, Scott MD. Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation. Integr Biol (Camb). 2018 Mar 23. doi: 10.1039/C7IB00191F. [Epub ahead of print] PubMed PMID: 29570200. https://www.ncbi.nlm.nih.gov/pubmed/29570200?dopt=Abstract

8. Majewski DD, Worrall LJ, Strynadka NC. Secretins revealed: structural insights into the giant gated outer membrane portals of bacteria. Curr Opin Struct Biol. 2018 Mar 23;51:61-72. doi: 10.1016/j.sbi.2018.02.008. [Epub ahead of print] Review. PubMed PMID: 29579693. https://www.ncbi.nlm.nih.gov/pubmed/29579693?dopt=Abstract

9. Lam VYY, Raineki C, Takeuchi LE, Ellis L, Woodward TS, Weinberg J. Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects. Front Behav Neurosci. 2018 Mar 9;12:42. doi: 10.3389/fnbeh.2018.00042. eCollection 2018. PubMed PMID: 29593510; PubMed Central PMCID: PMC5855032. https://www.ncbi.nlm.nih.gov/pubmed/29593510?dopt=Abstract

Mar 19 Pubcrawler Hits:

1. Gardill BR, Rivera-Acevedo RE, Tung CC, Okon M, McIntosh LP, Van Petegem F. The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations. Sci Rep. 2018 Mar 14;8(1):4483. doi: 10.1038/s41598-018-22713-y. PMID: 29540853. https://www.ncbi.nlm.nih.gov/pubmed/29540853

2.  Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Dev Dyn. 2018 Mar 13. doi: 10.1002/dvdy.24626. [Epub ahead of print]. PMID: 29532564.  https://www.ncbi.nlm.nih.gov/pubmed/29532564

3. Tang WL, Tang WH, Szeitz A, Kulkarni J, Cullis P, Li SD. Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery. Biomaterials. 2018 Mar 3;166:13-26. doi: 10.1016/j.biomaterials.2018.03.004. [Epub ahead of print]. PMID: 29529479. https://www.ncbi.nlm.nih.gov/pubmed/29529479

Mar 12 Pubcrawler Hits:

1. Foley JH, Conway EM. Basic weapons to degrade C3a and C5a. J Thromb Haemost. 2018 Mar 8. doi: 10.1111/jth.13999. [Epub ahead of print]. PMID: 29518284. https://www.ncbi.nlm.nih.gov/pubmed/29518284

2. Conway EM. Complement-coagulation connections. Blood Coagul Fibrinolysis. 2018 Mar 6. doi: 10.1097/MBC.0000000000000720. [Epub ahead of print]. PMID: 29517503.  https://www.ncbi.nlm.nih.gov/pubmed/29517503

Feb 26 Pubcrawler Hits:

1. Cain SM, Tyson JR, Choi HB, Ko R, Lin PJC, LeDue JM, Powell KL, Bernier LP, Rungta RL, Yang Y, Cullis PR, O'Brien TJ, MacVicar BA, Snutch TP. CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons. Epilepsia. 2018 Feb 21. doi: 10.1111/epi.14018. [Epub ahead of print. PMID: 29468672. https://www.ncbi.nlm.nih.gov/pubmed/29468672

2. Setiaputra D, Ahmad S, Dalwadi U, Steunou AL, Lu S, Ross JD, Dong MQ, Côté J, Yip CK. Molecular architecture of the essential yeast histone acetyltransferase complex NuA4 redefines its multi-modularity. Mol Cell Biol. 2018 Feb 20. pii: MCB.00570-17. doi: 10.1128/MCB.00570-17. [Epub ahead of print] PMID: 29463645. https://www.ncbi.nlm.nih.gov/pubmed/29463645

3. Wang JC, Lee JY, Dang-Lawson M, Pritchard C, Gold MR. The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center. Small GTPases. 2018 Feb 19:0. doi: 10.1080/21541248.2018.1441626. [Epub ahead of print]. PMID: 29457987. https://www.ncbi.nlm.nih.gov/pubmed/29457987

4. Cardenas E, Orellana LH, Konstantinidis KT, Mohn WW. Effects of timber harvesting on the genetic potential for carbon and nitrogen cycling in five North American forest ecozones. Sci Rep. 2018 Feb 16;8(1):3142. doi: 10.1038/s41598-018-21197-0. PMID: 29453368. https://www.ncbi.nlm.nih.gov/pubmed/29453368

Feb 19 Pubcrawler Hits:

1. Millar D, Murphy L, Labrie A, Maurer-Spurej E. Routine Screening Method for Microparticles in Platelet Transfusions. J Vis Exp. 2018 Jan 31. doi: 10.3791/56893. PMID: 29443045. https://www.ncbi.nlm.nih.gov/pubmed/29443045

2. Dommerholt MB, Dionne DA, Hutchinson DF, Kruit JK, Johnson JD. Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage. J Endocrinol. 2018 Feb 9. doi: 10.1530/JOE-17-0505. [Epub ahead of print] PMID: 29439088. https://www.ncbi.nlm.nih.gov/pubmed/29439088

3. Jagdeo JM, Dufour A, Klein T, Solis N, Kleifeld O, Kizhakkedathu J, Luo H, Overall CM, Jan E. N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection. J Virol. 2018 Feb 7. doi: 10.1128/JVI.02211-17. [Epub ahead of print] PMID: 29437971. https://www.ncbi.nlm.nih.gov/pubmed/29437971

4. Farr Zuend C, Nomellini JF, Smit J, Horwitz MS. Generation of a Dual-Target, Safe, Inexpensive Microbicide that Protects Against HIV-1 and HSV-2 Disease. Sci Rep. 2018 Feb 12;8(1):2786. doi: 10.1038/s41598-018-21134-1. PMID: 29434285.  https://www.ncbi.nlm.nih.gov/pubmed/29434285

5. Johnston ZC, Bellingham M, Filis P, Soffientini U, Hough D, Bhattacharya S, Simard M, Hammond GL, King P, O'Shaughnessy PJ, Fowler PA. The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester. BMC Med. 2018 Feb 12;16(1):23. doi: 10.1186/s12916-018-1009-7. PMID: 29429410. https://www.ncbi.nlm.nih.gov/pubmed/29429410

Feb 12 Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Simpson EM, Brown CJ. Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse. Hum Mol Genet. 2018 Feb 1. doi: 10.1093/hmg/ddy039. [Epub ahead of print] PubMed PMID: 29401310. https://www.ncbi.nlm.nih.gov/pubmed/29401310?dopt=Abstract

2. Saber N, Bruin JE, O'Dwyer S, Schuster H, Rezania A, Kieffer TJ. Sex differences in maturation of human embryonic stem cell-derived beta cells in mice. Endocrinology. 2018 Feb 5. doi: 10.1210/en.2018-00048. [Epub ahead of print] PubMed PMID: 29420708. https://www.ncbi.nlm.nih.gov/pubmed/29420708?dopt=Abstract

3. De Silva E, Kim H. Drug-induced thrombocytopenia: Focus on platelet apoptosis. Chem Biol Interact. 2018 Feb 1. pii: S0009-2797(17)30840-2. doi: 10.1016/j.cbi.2018.01.015. [Epub ahead of print] Review. PubMed PMID: 29410286. https://www.ncbi.nlm.nih.gov/pubmed/29410286?dopt=Abstract

4. Hayes M, Choudhary V, Ojha N, Shin JJ, Han GS, Carman GM, Loewen CJ, Prinz WA, Levine T. Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes. Microb Cell. 2017 Dec 28;5(2):88-103. doi: 10.15698/mic2018.02.614. PubMed PMID: 29417057; PubMed Central PMCID: PMC5798408. https://www.ncbi.nlm.nih.gov/pubmed/29417057?dopt=Abstract

5. Heger TJ, Giesbrecht IJW, Gustavsen J, Del Campo J, Kellogg CTE, Hoffman KM, Lertzman K, Mohn WW, Keeling PJ. High-throughput environmental sequencing reveals high diversity of litter and moss associated protist communities along a gradient of drainage and tree productivity. Environ Microbiol. 2018 Feb 7. doi: 10.1111/1462-2920.14061. [Epub ahead of print] PubMed PMID: 29417706. https://www.ncbi.nlm.nih.gov/pubmed/29417706?dopt=Abstract

Feb 05 Pubcrawler Hits:

1. Fakhraee M, Crowe SA, Katsev S. Sedimentary sulfur isotopes and Neoarchean ocean oxygenation. Sci Adv. 2018 Jan 24;4(1):e1701835. doi: 10.1126/sciadv.1701835. eCollection 2018 Jan. PubMed PMID: 29376118; PubMed Central PMCID: PMC5783677. https://www.ncbi.nlm.nih.gov/pubmed/29376118?dopt=Abstract

2. Devine DV. Pathogen Inactivation Strategies to Improve Blood Safety: Let's Not Throw Pathogen-Reduced Platelets Out With Their Bath Water. JAMA Oncol. 2018 Feb doi: 10.1001/jamaoncol.2017.4949. [Epub ahead of print] PubMed PMID: 29392303. https://www.ncbi.nlm.nih.gov/pubmed/29392303?dopt=Abstract

3. Wang JC, Bolger-Munro M, Gold MR. Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods Mol Biol. 2018;1707:131-161. doi: 10.1007/978-1-4939-7474-0_10. PubMed PMID: 29388105. https://www.ncbi.nlm.nih.gov/pubmed/29388105?dopt=Abstract

4. Holert J, Cardenas E, Bergstrand LH, Zaikova E, Hahn AS, Hallam SJ, Mohn WW. Metagenomes Reveal Global Distribution of Bacterial Steroid Catabolism in Natural, Engineered, and Host Environments. MBio. 2018 Jan 30;9(1). pii:e02345-17. doi: 10.1128/mBio.02345-17. PubMed PMID: 29382738. https://www.ncbi.nlm.nih.gov/pubmed/29382738?dopt=Abstract 

Jan 29 Pubcrawler Hits:

1. Kumar P, Kizhakkedathu JN, Straus SK. Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo. Biomolecules. 2018 Jan 19;8(1). pii: E4. doi: 10.3390/biom8010004. Review. PubMed PMID: 29351202. https://www.ncbi.nlm.nih.gov/pubmed/29351202?dopt=Abstract

2. Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut. 2018 Jan 23. pii: gutjnl-2017-314426. doi: 10.1136/gutjnl-2017-314426. [Epub ahead of print] PubMed PMID: 29363536. https://www.ncbi.nlm.nih.gov/pubmed/29363536?dopt=Abstract

3. Kaiser JC, King AN, Grigg JC, Sheldon JR, Edgell DR, Murphy MEP, Brinsmade SR, Heinrichs DE. Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide. PLoS Genet. 2018 Jan 22;14(1):e1007159. doi: 10.1371/journal.pgen.1007159. [Epub ahead of print] PubMed PMID: 29357354. https://www.ncbi.nlm.nih.gov/pubmed/29357354?dopt=Abstract

4. Campiglio M, Costé de Bagneaux P, Ortner NJ, Tuluc P, Van Petegem F, Flucher BE. STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation. Proc Natl Acad Sci U S A. 2018 Jan 23. pii: 201715997. doi: 10.1073/pnas.1715997115. [Epub ahead of print] PubMed PMID: 29363593. https://www.ncbi.nlm.nih.gov/pubmed/29363593?dopt=Abstract

5. Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS. PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance. J Antimicrob Chemother. 2018 Jan 19. doi: 10.1093/jac/dkx531. [Epub ahead of print] PubMed PMID: 29360990. https://www.ncbi.nlm.nih.gov/pubmed/29360990?dopt=Abstract

6. Petrelli B, Weinberg J, Hicks GG. Effects of Prenatal Alcohol Exposure (PAE): Insights into FASD using PAE Mouse Models. Biochem Cell Biol. 2018 Jan 25. doi: 10.1139/bcb-2017-0280. [Epub ahead of print] PubMed PMID: 29370535. https://www.ncbi.nlm.nih.gov/pubmed/29370535?dopt=Abstract

Jan 22 Pubcrawler Hits:

1. Macdonald LC, Kim RY, Kurata HT, Fedida D. Probing the molecular basis of hERG drug block with unnatural amino acids. Sci Rep. 2018 Jan 10;8(1):289. doi: 10.1038/s41598-017-18448-x. PubMed PMID: 29321549; PubMed Central PMCID: PMC5762913. https://www.ncbi.nlm.nih.gov/pubmed/29321549?dopt=Abstract

2. Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S. Transmembrane Pickets onnect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell.  018 Jan 11;172(1-2):305-317.e10. doi: 10.1016/j.cell.2017.12.023. PubMed PMID: 29328918. https://www.ncbi.nlm.nih.gov/pubmed/29328918?dopt=Abstract

3. Bi C, Tham DKL, Perronnet C, Joshi B, Nabi IR, Moukhles H. The Oxidative Stress-Induced Increase in the Membrane Expression of the Water-Permeable Channel Aquaporin-4 in Astrocytes Is Regulated by Caveolin-1 Phosphorylation. Front Cell Neurosci. 2017 Dec 20;11:412. doi: 10.3389/fncel.2017.00412. eCollection 2017. PubMed PMID: 29326556; PubMed Central PMCID: PMC5742350. https://www.ncbi.nlm.nih.gov/pubmed/29326556?dopt=Abstract

4. Lussier AA, Morin AM, MacIsaac JL, Salmon J, Weinberg J, Reynolds JN, Pavlidis P, Chudley AE, Kobor MS. DNA methylation as a predictor of fetal alcohol spectrum disorder. Clin Epigenetics. 2018 Jan 12;10:5. doi: 10.1186/s13148-018-0439-6. eCollection 2018. PubMed PMID: 29344313; PubMed Central PMCID: PMC5767049. https://www.ncbi.nlm.nih.gov/pubmed/29344313?dopt=Abstract

5. Dalwadi U, Yip CK. Structural insights into the function of Elongator. Cell Mol Life Sci. 2018 Jan 13. doi: 10.1007/s00018-018-2747-6. [Epub ahead of print] Review. PubMed PMID: 29332244. https://www.ncbi.nlm.nih.gov/pubmed/29332244?dopt=Abstract

Jan 15 Pubcrawler Hits:

1. Linde C, Cleland JGF, Gold MR, Claude Daubert J, Tang ASL, Young JB, Sherfesee L, Abraham WT. The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. Eur J Heart Fail. 2018 Jan 4. doi: 10.1002/ejhf.1133. [Epub ahead of print] PubMed PMID: 29314424. https://www.ncbi.nlm.nih.gov/pubmed/29314424?dopt=Abstract

2. Macdonald SS, Patel A, Larmour VLC, Morgan-Lang C, Hallam SJ, Mark BL, WithersSG. Structural and mechanistic analysis of a β-glycoside phosphorylase identified by screening a metagenomic library. J Biol Chem. 2018 Jan 9. pii: jbc.RA117.000948. doi: 10.1074/jbc.RA117.000948. [Epub ahead of print] PubMed PMID: 29317495. https://www.ncbi.nlm.nih.gov/pubmed/29317495?dopt=Abstract

3. Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH. A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses. Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4. PubMed PMID: 29311608; PubMed Central PMCID: PMC5758616. https://www.ncbi.nlm.nih.gov/pubmed/29311608?dopt=Abstract

4. Lee-Sayer SSM, Maeshima N, Dougan MN, Dahiya A, Arif AA, Dosanjh M, Maxwell CA, Johnson P. Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells. Eur J Immunol. 2018 Jan 8. doi: 1002/eji.201747263. [Epub ahead of print] PubMed PMID: 29315518. https://www.ncbi.nlm.nih.gov/pubmed/29315518?dopt=Abstract

5. Solis N, Overall CM. Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS). Methods Mol Biol. 2018;1731:15-28. doi:10.1007/978-1-4939-7595-2_2. PubMed PMID: 29318539. https://www.ncbi.nlm.nih.gov/pubmed/29318539?dopt=Abstract

6. Grieco TM, Richman JM. Coordination of bilateral tooth replacement in the juvenile gecko is continuous with in ovo patterning. Evol Dev. 2018 Jan 10. doi: 1111/ede.12247. [Epub ahead of print] PubMed PMID: 29318754. https://www.ncbi.nlm.nih.gov/pubmed/29318754?dopt=Abstract

7. Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y. Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages. Sci Rep. 2018 Jan 9;8(1):155. doi: 10.1038/s41598-017-18547-9. PubMed PMID: 29317718. https://www.ncbi.nlm.nih.gov/pubmed/29317718?dopt=Abstract

Jan 8 Pubcrawler Hits:

1. Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. PubMed PMID: 29296696; PubMed Central PMCID: PMC5744055. https://www.ncbi.nlm.nih.gov/pubmed/29296696?dopt=Abstract

Jan 1 Pubcrawler Hits:

1. Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, Brömme D. Tanshinones: A novel class of ectosteric anti-resorptives. Br J Pharmacol. 2017 Dec 26. doi: 10.1111/bph.14133. [Epub ahead of print] PubMed PMID: 29278432. https://www.ncbi.nlm.nih.gov/pubmed/29278432?dopt=Abstract

2. Galibert M, Wartenberg M, Lecaille F, Saidi A, Mavel S, Joulin-Giet A, Korkmaz B, Brömme D, Aucagne V, Delmas AF, Lalmanach G. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. Eur J Med Chem. 2017 Dec 7;144:201-210. doi: 10.1016/j.ejmech.2017.12.012. [Epub ahead of print] PubMed PMID: 29272750. https://www.ncbi.nlm.nih.gov/pubmed/29272750?dopt=Abstract

3. Simard M, Underhill C, Hammond GL. Functional Implications of Corticosteroid-binding Globulin N-Glycosylation. J Mol Endocrinol. 2017 Dec 22. pii: JME-17-0234. doi: 10.1530/JME-17-0234. [Epub ahead of print] PubMed PMID: 29273683. https://www.ncbi.nlm.nih.gov/pubmed/29273683?dopt=Abstract

4. Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. 2017 Dec 19. pii: S0016-5085(17)36711-2. doi: 10.1053/j.gastro.2017.12.007. [Epub ahead of print] PubMed PMID: 29273451. https://www.ncbi.nlm.nih.gov/pubmed/29273451?dopt=Abstract