LSI Pub Corner

LSI Pub Corner

Find the latest publications from LSI’s researchers here:


July 15, Pubcrawler Hits:

1. Banerjee R, Zhu Y, Brownrigg GP, Moravcova R, Rogalski JC, Foster LJ, Johnson JD, Kolic J. Beta-hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets. Endocrinology. 2024 Jul 6:bqae079. doi: 10.1210/endocr/bqae079. Epub ahead of print. PMID: 38970533.

2. Bodnar TS, Ainsworth-Cruickshank G, Billy V, Wegener Parfrey L, Weinberg J, Raineki C. Alcohol consumption during pregnancy differentially affects the fecal microbiota of dams and offspring. Sci Rep. 2024 Jul 12;14(1):16121. doi: 10.1038/s41598-024-64313-z. PMID: 38997303; PMCID: PMC11245617.

3. Ghezzi H, Fan YM, Ng KM, Burckhardt JC, Pepin DM, Lin X, Ziels RM, Tropini C. PUPpy: a primer design pipeline for substrain-level microbial detection and absolute quantification. mSphere. 2024 Jul 9:e0036024. doi: 10.1128/msphere.00360-24. Epub ahead of print. PMID: 38980072.

4. Yazdani-Ahmadabadi H, Yu K, Gonzalez K, Luo HD, Lange D, Kizhakkedathu JN. Long-Term Prevention of Biofilm Formation by Polycatechol-Based Supramolecular Assemblies with Low Molecular Weight Polymers on Surfaces. ACS Appl Mater Interfaces. 2024 Jul 9. doi: 10.1021/acsami.4c02371. Epub ahead of print. PMID: 38980701.

July 8, Pubcrawler Hits:

1. Kamanzi A, Zhang Y, Gu Y, Liu F, Berti R, Wang B, Saadati F, Ciufolini MA, Kulkarni J, Cullis P, Leslie S. Quantitative Visualization of Lipid Nanoparticle Fusion as a Function of Formulation and Process Parameters. ACS Nano. 2024 Jul 5. doi: 10.1021/acsnano.3c12981. Epub ahead of print. PMID: 38968430.

2. Vlok M, Solis N, Sadasivan J, Mohamud Y, Warsaba R, Kizhakkedathu J, Luo H, Overall CM, Jan E. Identification of the proteolytic signature in CVB3-infected cells. J Virol. 2024 Jul 2:e0049824. doi: 10.1128/jvi.00498-24. Epub ahead of print. PMID: 38953667.

3. Kolic J, Sun WG, Cen HH, Ewald JD, Rogalski JC, Sasaki S, Sun H, Rajesh V, Xia YH, Moravcova R, Skovsø S, Spigelman AF, Manning Fox JE, Lyon J, Beet L, Xia J, Lynn FC, Gloyn AL, Foster LJ, MacDonald PE, Johnson JD. Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Cell Metab. 2024 Jul 2;36(7):1619-1633.e5. doi: 10.1016/j.cmet.2024.06.001. PMID: 38959864.

4. Guo CY, Mo R, Kim H. Surface topography modulates initial platelet adhesion to titanium substrata. J Oral Biol Craniofac Res. 2024 Jul-Aug;14(4):471-477. doi: 10.1016/j.jobcr.2024.02.008. Epub 2024 Jun 7. PMID: 38962718; PMCID: PMC11220530.

5. Tophkhane SS, Fu K, Verheyen EM, Richman JM. Craniofacial studies in chicken embryos confirm the pathogenicity of human FZD2 variants associated with Robinow syndrome. Dis Model Mech. 2024 Jun 1;17(6):dmm050584. doi: 10.1242/dmm.050584. Epub 2024 Jul 5. PMID: 38967226.

6. Töpfer U, Ryu J, Guerra Santillán KY, Schulze J, Fischer-Friedrich E, Tanentzapf G, Dahmann C. AdamTS proteases control basement membrane heterogeneity and organ shape in Drosophila. Cell Rep. 2024 Jun 28;43(7):114399. doi: 10.1016/j.celrep.2024.114399. Epub ahead of print. PMID: 38944833.

7. Kwan JZJ, Nguyen TF, Teves SS. TBP facilitates RNA Polymerase I transcription following mitosis. RNA Biol. 2024 Jan;21(1):42-51. doi: 10.1080/15476286.2024.2375097. Epub 2024 Jul 3. PMID: 38958280; PMCID: PMC11225926.

8. Black B, da Silva LBR, Hu G, Qu X, Smith DFQ, Magaña AA, Horianopoulos LC, Caza M, Attarian R, Foster LJ, Casadevall A, Kronstad JW. Glutathione-mediated redox regulation in Cryptococcus neoformans impacts virulence. Nat Microbiol. 2024 Jul 2. doi: 10.1038/s41564-024-01721-x. Epub ahead of print. PMID: 38956248.

9. Yu Z, Liang YC, Berton S, Liu L, Zou J, Chen L, Xu Z, Luo C, Sun J, Yang W. Small Molecule Targeting PPM1A Activates Autophagy for Mycobacterium tuberculosis Host-Directed Therapy. J Med Chem. 2024 Jul 3. doi: 10.1021/acs.jmedchem.4c00513. Epub ahead of print. PMID: 38958057.

July 1, Pubcrawler Hits:

1. Vaikakkara Chithran A, Allan DW, O'Connor TP. Adult expression of the cell adhesion protein Fasciclin 3 is required for the maintenance of adult olfactory interneurons. J Cell Sci. 2024 Jun 15;137(12):jcs261759. doi: 10.1242/jcs.261759. Epub 2024 Jun 27. PMID: 38934299.

2. Jackson J, Shademani A, Dosanjh M, Dietrich C, Pryjma M, Lambert DM, Thompson CJ. Combinations of Cannabinoids with Silver Salts or Silver Nanoparticles for Synergistic Antibiotic Effects against Methicillin-Resistant Staphylococcus aureus. Antibiotics (Basel). 2024 May 22;13(6):473. doi: 10.3390/antibiotics13060473. PMID: 38927140; PMCID: PMC11200472.

3. Ota A, Iguchi T, Nitta S, Muro R, Mino N, Tsukasaki M, Penninger JM, Nitta T, Takayanagi H. Synchronized development of thymic eosinophils and thymocytes. Int Immunol. 2024 Jun 25:dxae037. doi: 10.1093/intimm/dxae037. Epub ahead of print. PMID: 38916145.

June 24, Pubcrawler Hits:

1. Fettig NM, Pu A, Osborne LC, Gommerman JL. The influence of aging and the microbiome in multiple sclerosis and other neurologic diseases. Immunol Rev. 2024 Jun 18. doi: 10.1111/imr.13361. Epub ahead of print. PMID: 38890777.

2. Nasseri SA, Lazarski AC, Lemmer IL, Zhang CY, Brencher E, Chen HM, Sim L, Panwar D, Betschart L, Worrall LJ, Brumer H, Strynadka NCJ, Withers SG. An alternative broad-specificity pathway for glycan breakdown in bacteria. Nature. 2024 Jun 19. doi: 10.1038/s41586-024-07574-y. Epub ahead of print. PMID: 38898276.

3. Arad M, Ku K, Frey C, Hare R, McAfee A, Ghafourifar G, Foster LJ. What proteomics has taught us about honey bee (Apis mellifera) health and disease. Proteomics. 2024 Jun 19:e2400075. doi: 10.1002/pmic.202400075. Epub ahead of print. PMID: 38896501.

4. Luo Y, Safabakhsh S, Palumbo A, Fiset C, Shen C, Parker J, Foster LJ, Laksman Z. Sex-Based Mechanisms of Cardiac Development and Function: Applications for Induced-Pluripotent Stem Cell Derived-Cardiomyocytes. Int J Mol Sci. 2024 May 29;25(11):5964. doi: 10.3390/ijms25115964. PMID: 38892161; PMCID: PMC11172775.

5. McAfee A, French SK, Wizenberg SB, Newburn LR, Tsvetkov N, Higo H, Common J, Pernal SF, Giovenazzo P, Hoover SE, Guzman-Novoa E, Currie RW, Veiga PW, Conflitti IM, Pepinelli M, Tran L, Zayed A, Guarna MM, Foster LJ. Higher prevalence of sacbrood virus in Apis mellifera (Hymenoptera: Apidae) colonies after pollinating highbush blueberries. J Econ Entomol. 2024 Jun 15:toae119. doi: 10.1093/jee/toae119. Epub ahead of print. PMID: 38877967.

June 17, Pubcrawler Hits:

1. Sastre D, Fedida D. Voltage Clamp Fluorometry: Illuminating the Dynamics of Ion Channels. Methods Mol Biol. 2024;2796:119-138. doi: 10.1007/978-1-0716-3818-7_8. PMID: 38856899.

2. Kaiser M, Zikmund T, Vora S, Metscher B, Adameyko I, Richman JM, Kaiser J. 3D atlas of the human fetal chondrocranium in the middle trimester. Sci Data. 2024 Jun 13;11(1):626. doi: 10.1038/s41597-024-03455-1. PMID: 38871782; PMCID: PMC11176318.

June 10, Pubcrawler Hits:

1. Roccor R, Wolf ME, Liu J, Eltis LD. The catabolism of ethylene glycol by Rhodococcus jostii RHA1 and its dependence on mycofactocin. Appl Environ Microbiol. 2024 Jun 5:e0041624. doi: 10.1128/aem.00416-24. Epub ahead of print. PMID: 38837369.

2. Frey C, Arad M, Ku K, Hare R, Balagtas R, Shi Y, Moon KM, Foster LJ, Ghafourifar G. Development of automated proteomic workflows utilizing silicon-based coupling agents. J Proteomics. 2024 Jun 4:105215. doi: 10.1016/j.jprot.2024.105215. Epub ahead of print. PMID: 38843981.

June 3, Pubcrawler Hits:

1. Chen Y, Chapagain S, Chien J, Pereira HS, Patel TR, Inoue-Nagata AK, Jan E. Factor-Dependent Internal Ribosome Entry Site and -1 Programmed Frameshifting Signal in the Bemisia-Associated Dicistrovirus 2. Viruses. 2024 Apr 28;16(5):695. doi: 10.3390/v16050695. PMID: 38793577; PMCID: PMC11125867.

2. Durrer C, Islam H, Cen HH, Garzon MDM, Lyu X, McKelvey S, Singer J, Batterham AM, Long JZ, Johnson JD, Little JP. A secondary analysis of indices of hepatic and beta cell function following 12 weeks of carbohydrate and energy restriction vs. free-living control in adults with type 2 diabetes. Nutr Metab (Lond). 2024 May 27;21(1):29. doi: 10.1186/s12986-024-00807-x. PMID: 38797835; PMCID: PMC11129411.

3. Chao CF, Pesch YY, Yu H, Wang C, Aristizabal MJ, Huan T, Tanentzapf G, Rideout E. An important role for triglyceride in regulating spermatogenesis. Elife. 2024 May 28;12:RP87523. doi: 10.7554/eLife.87523. PMID: 38805376; PMCID: PMC11132686.

4. Abram QH, Landry BN, Wang AB, Kothe RF, Hauch HCH, Sagan SM. The myriad roles of RNA structure in the flavivirus life cycle. RNA Biol. 2024 Jan;21(1):14-30. doi: 10.1080/15476286.2024.2357857. Epub 2024 May 26. PMID: 38797925; PMCID: PMC11135854.

May 27, Pubcrawler Hits:

1. Cau MF, Ferraresso F, Seadler M, Badior K, Zhang Y, Ketelboeter LM, Rodriguez GG, Chen T, Ferraresso M, Wietrzny A, Robertson M, Haugen A, Cullis PR, de Moya M, Dyer M, Kastrup CJ. siRNA-mediated reduction of a circulating protein in swine using lipid nanoparticles. Mol Ther Methods Clin Dev. 2024 Apr 27;32(2):101258. doi: 10.1016/j.omtm.2024.101258. PMID: 38779336; PMCID: PMC11109470.

2. Mittendorfer B, Johnson JD, Solinas G, Jansson PA. Insulin Hypersecretion as Promoter of Body Fat Gain and Hyperglycemia. Diabetes. 2024 Jun 1;73(6):837-843. doi: 10.2337/dbi23-0035. PMID: 38768368; PMCID: PMC11109786.

3. Paul M, Hong F, Falet H, Kim H. Gelsolin regulates receptor-mediated and fluid-phase endocytosis in platelets. J Thromb Haemost. 2024 May 20:S1538-7836(24)00293-9. doi: 10.1016/j.jtha.2024.05.010. Epub ahead of print. PMID: 38777258.

4. Pasqualotto BA, Nelson A, Deheshi S, Sheldon CA, Vogl AW, Rintoul GL. Impaired mitochondrial morphological plasticity and failure of mitophagy associated with the G11778A mutation of LHON. Biochem Biophys Res Commun. 2024 May 14;721:150119. doi: 10.1016/j.bbrc.2024.150119. Epub ahead of print. PMID: 38768545.

5. Moradimotlagh A, Brar HK, Chen S, Moon KM, Foster LJ, Reiner N, Nandan D. Characterization of Argonaute-containing protein complexes in Leishmania-infected human macrophages. PLoS One. 2024 May 23;19(5):e0303686. doi: 10.1371/journal.pone.0303686. PMID: 38781128; PMCID: PMC11115314.

May 20, Pubcrawler Hits:

1. Hadjesfandiari N, Serrano K, Richardson-Sanchez T, Barakauskas VE, Yi QL, Murphy M, Devine DV. Measurement of lead, mercury, and cadmium in blood donors in Canada. Transfusion. 2024 May 16. doi: 10.1111/trf.17872. Epub ahead of print. PMID: 38752406.

2. Cesar Ramos de Jesus H, Solis N, Machado Y, Pablos I, Bell PA, Kappelhoff R, Grin PM, Sorgi CA, Butler GS, Overall CM. Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CLpro main protease (Mpro) from proteomic identification of P6-P6' active site specificity. J Virol. 2024 May 14:e0004924. doi: 10.1128/jvi.00049-24. Epub ahead of print. PMID: 38742901.

3. Kenward C, Vuckovic M, Paetzel M, Strynadka NCJ. Kinetic comparison of all eleven viral polyprotein cleavage site processing events by SARS-CoV-2 Main Protease using a linked protein FRET platform. J Biol Chem. 2024 May 13:107367. doi: 10.1016/j.jbc.2024.107367. Epub ahead of print. PMID: 38750796.

4. Sharma S, Houfani AA, Foster LJ. Pivotal functions and impact of long con-coding RNAs on cellular processes and genome integrity. J Biomed Sci. 2024 May 14;31(1):52. doi: 10.1186/s12929-024-01038-1. PMID: 38745221; PMCID: PMC11092263.

5. Pereiro I, Fomitcheva-Khartchenko A, Kaigala GV. Enhancing the Efficiency of Conventional Surface Immunoassays Within Standard Labware Using Microscale Flows. Methods Mol Biol. 2024;2804:103-115. doi: 10.1007/978-1-0716-3850-7_6. PMID: 38753143.

May 6, Pubcrawler Hits:

1. Lengacher NA, Tomlinson JJ, Jochum AK, Franz J, Hasan Ali O, Flatz L, Jochum W, Penninger J; aSCENT-PD Investigators; Stadelmann C, Woulfe JM, Schlossmacher MG. Neuropathological assessment of the olfactory bulb and tract in individuals with COVID-19. Acta Neuropathol Commun. 2024 May 3;12(1):70. doi: 10.1186/s40478-024-01761-8. PMID: 38698465; PMCID: PMC11067107.

2. Wei KH, Chatla K, Bachtrog D. Single-cell RNA-seq of Drosophila miranda testis reveals the evolution and trajectory of germline sex chromosome regulation. PLoS Biol. 2024 Apr 30;22(4):e3002605. doi: 10.1371/journal.pbio.3002605. Epub ahead of print. PMID: 38687805.

April 29, Pubcrawler Hits:

1. Piccolo D, Zarouchlioti C, Bellingham J, Guarascio R, Ziaka K, Molday RS, Cheetham ME. A Proximity Complementation Assay to Identify Small Molecules That Enhance the Traffic of ABCA4 Misfolding Variants. Int J Mol Sci. 2024 Apr 20;25(8):4521. doi: 10.3390/ijms25084521. PMID: 38674104; PMCID: PMC11050442.

2. Camp D, Venkatesh B, Solianova V, Varela L, Goult BT, Tanentzapf G. The actin binding sites of talin have both distinct and complementary roles in cell-ECM adhesion. PLoS Genet. 2024 Apr 25;20(4):e1011224. doi: 10.1371/journal.pgen.1011224. Epub ahead of print. PMID: 38662776.

3. Brotto LA, Basson R, Grabovac A, Chivers ML, Zdaniuk B, Bodnar TS, Weinberg J. Impact of mindfulness versus supportive sex education on stress in women with sexual interest/arousal disorder. J Behav Med. 2024 Apr 26. doi: 10.1007/s10865-024-00491-5. Epub ahead of print. PMID: 38668816.

4. Bosch TCG, Wigley M, Colomina B, Bohannan B, Meggers F, Amato KR, Azad MB, Blaser MJ, Brown K, Dominguez-Bello MG, Ehrlich SD, Elinav E, Finlay BB, Geddie K, Geva-Zatorsky N, Giles-Vernick T, Gros P, Guillemin K, Haraoui LP, Johnson E, Keck F, Lorimer J, McFall-Ngai MJ, Nichter M, Pettersson S, Poinar H, Rees T, Tropini C, Undurraga EA, Zhao L, Melby MK. The potential importance of the built-environment microbiome and its impact on human health. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2313971121. doi: 10.1073/pnas.2313971121. Epub 2024 Apr 25. PMID: 38662573.

5. MacArthur TA, Goswami J, Navarro SM, Vappala S, La CC, Yudin N, Zietlow J, Smith SA, Morrissey JH, Spears GM, Bailey KR, Dong JF, Kozar RA, Kizhakkedathu JN, Park MS. Inhibitors of Inorganic Polyphosphate and Nucleic Acids Attenuate in vitro Thrombin Generation in Plasma from Trauma Patients. Shock. 2024 Mar 25. doi: 10.1097/SHK.0000000000002362. Epub ahead of print. PMID: 38662595.

6. Hoang KL, Salguero-Gómez R, Pike VL, King KC. The impacts of host association and perturbation on symbiont fitness. Symbiosis. 2024;92(3):439-451. doi: 10.1007/s13199-024-00984-6. Epub 2024 Apr 2. PMID: 38666134; PMCID: PMC11039428.

7. Brough Z, Zhao Z, Duong van Hoa F. From bottom-up to cell surface proteomics: detergents or no detergents, that is the question. Biochem Soc Trans. 2024 Apr 26:BST20231020. doi: 10.1042/BST20231020. Epub ahead of print. PMID: 38666604.

April 22, Pubcrawler Hits:

1. Anwar MA, Keshteli AH, Yang H, Wang W, Li X, Messier HM, Cullis PR, Borchers CH, Fraser R, Wishart DS. Blood-Based Multiomics-Guided Detection of a Precancerous Pancreatic Tumor. OMICS. 2024 Apr 17. doi: 10.1089/omi.2023.0278. Epub ahead of print. PMID: 38634790.

2. French SK, Pepinelli M, Conflitti IM, Jamieson A, Higo H, Common J, Walsh EM, Bixby M, Guarna MM, Pernal SF, Hoover SE, Currie RW, Giovenazzo P, Guzman-Novoa E, Borges D, Foster LJ, Zayed A. Honey bee stressor networks are complex and dependent on crop and region. Curr Biol. 2024 Apr 15:S0960-9822(24)00379-8. doi: 10.1016/j.cub.2024.03.039. Epub ahead of print. PMID: 38636513.

3. Greenrod STE, Cazares D, Johnson S, Hector TE, Stevens EJ, MacLean RC, King KC. Warming alters life-history traits and competition in a phage community. Appl Environ Microbiol. 2024 Apr 16:e0028624. doi: 10.1128/aem.00286-24. Epub ahead of print. PMID: 38624196.

April 15, Pubcrawler Hits:

1. Short L, Holt RA, Cullis PR, Evgin L. Direct in vivo CAR T cell engineering. Trends Pharmacol Sci. 2024 Apr 12:S0165-6147(24)00052-X. doi: 10.1016/ Epub ahead of print. PMID: 38614815.

2. Lin N, Taghizadehmakoei A, Polovina L, McLean I, Santana-Martínez JC, Naese C, Moraes C, Hallam SJ, Dahmen J. 3D Bioprinting of Food Grade Hydrogel Infused with Living Pleurotus ostreatus Mycelium in Non-sterile Conditions. ACS Appl Bio Mater. 2024 Apr 8. doi: 10.1021/acsabm.4c00048. Epub ahead of print. PMID: 38587496.

3. David SB, Ho KYL, Tanentzapf G, Zaritsky A. Formation of recurring transient Ca2+-based intercellular communities during Drosophila hematopoiesis. Proc Natl Acad Sci U S A. 2024 Apr 16;121(16):e2318155121. doi: 10.1073/pnas.2318155121. Epub 2024 Apr 11. PMID: 38602917.

4. Betancourt AJ, Wei KH, Huang Y, Lee YCG. Causes and Consequences of Varying Transposable Element Activity: An Evolutionary Perspective. Annu Rev Genomics Hum Genet. 2024 Apr 11. doi: 10.1146/annurev-genom-120822-105708. Epub ahead of print. PMID: 38603565.

April 8, Pubcrawler Hits:

1. Messing M, Gatti DM, Mashhouri S, Nantel S, Sultana S, Westhaver LP, Patel KD, Marshall AJ, Haeryfar SMM, Jenne CN, Abraham N, Melichar HJ, McNagny KM, Valdez Tejeira Y. A Retrospective Analysis of Leadership, Awardees, and Member Gender Representation of the Canadian Society for Immunology. J Immunol. 2024 Apr 15;212(8):1257-1267. doi: 10.4049/jimmunol.2300711. PMID: 38560813.

2. Tafech B, Rokhforouz MR, Leung J, Sung MM, Lin PJ, Sin DD, Lauster D, Block S, Quon BS, Tam Y, Cullis P, Feng JJ, Hedtrich S. Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions. Adv Healthc Mater. 2024 Apr 2:e2304525. doi: 10.1002/adhm.202304525. Epub ahead of print. PMID: 38563726.

3. Tophkhane SS, Richman JM. Tissues and signals with true organizer properties in craniofacial development. Curr Top Dev Biol. 2024;157:67-82. doi: 10.1016/bs.ctdb.2023.12.002. Epub 2023 Dec 30. PMID: 38556459.

4. Deng P, Xu A, Grin PM, Matthews K, Duffy SP, Ma H. Auto-amplification and spatial propagation of neutrophil extracellular traps. Commun Biol. 2024 Mar 29;7(1):386. doi: 10.1038/s42003-024-06074-z. PMID: 38553656; PMCID: PMC10980821.

5. MacMillan S, Hosgood SA, Walker-Panse L, Rahfeld P, Macdonald SS, Kizhakkedathu JN, Withers SG, Nicholson ML. Enzymatic conversion of human blood group A kidneys to universal blood group O. Nat Commun. 2024 Mar 30;15(1):2795. doi: 10.1038/s41467-024-47131-9. PMID: 38555382; PMCID: PMC10981661.

6. Jandu RS, Yu H, Zhao Z, Le HT, Kim S, Huan T, Duong van Hoa F. Capture of endogenous lipids in peptidiscs and effect on protein stability and activity. iScience. 2024 Mar 1;27(4):109382. doi: 10.1016/j.isci.2024.109382. PMID: 38577106; PMCID: PMC10993126.

April 1, Pubcrawler Hits:

1. Panwar P, Olesen JB, Blum G, Delaisse JM, Søe K, Brömme D. Real-time analysis of osteoclast resorption and fusion dynamics in response to bone resorption inhibitors. Sci Rep. 2024 Mar 28;14(1):7358. doi: 10.1038/s41598-024-57526-9. PMID: 38548807; PMCID: PMC10978898.

2. Bon CG, Grigg JC, Lee J, Robb CS, Caveney NA, Eltis LD, Strynadka NCJ. Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. J Struct Biol. 2024 Mar 23:108086. doi: 10.1016/j.jsb.2024.108086. Epub ahead of print. PMID: 38527711.

3. Pérez-Vargas J, Lemieux G, Thompson CAH, Désilets A, Ennis S, Gao G, Gordon DG, Schulz AL, Niikura M, Nabi IR, Krajden M, Boudreault PL, Leduc R, Jean F. Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals. Antiviral Res. 2024 Mar 26:105869. doi: 10.1016/j.antiviral.2024.105869. Epub ahead of print. PMID: 38548023.

4. Budzyński MA, Wong AKL, Faghihi A, Teves SS. A dynamic role for transcription factors in restoring transcription through mitosis. Biochem Soc Trans. 2024 Mar 25:BST20231022. doi: 10.1042/BST20231022. Epub ahead of print. PMID: 38526206.

5. Monteil VM, Wright SC, Dyczynski M, Kellner MJ, Appelberg S, Platzer SW, Ibrahim A, Kwon H, Pittarokoilis I, Mirandola M, Michlits G, Devignot S, Elder E, Abdurahman S, Bereczky S, Bagci B, Youhanna S, Aastrup T, Lauschke VM, Salata C, Elaldi N, Weber F, Monserrat N, Hawman DW, Feldmann H, Horn M, Penninger JM, Mirazimi A. Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells. Nat Microbiol. 2024 Mar 28. doi: 10.1038/s41564-024-01672-3. Epub ahead of print. PMID: 38548922.

6. Kilpiö T, Skarp S, Perjes A, Swan J, Kaikkonen L, Saarimaki S, Szokodi I, Penninger JM, Szabo Z, Magga J, Kerkela R. Apelin regulates skeletal muscle adaptation to exercise in a high intensity interval training (HIIT) model. Am J Physiol Cell Physiol. 2024 Mar 25. doi: 10.1152/ajpcell.00427.2023. Epub ahead of print. PMID: 38525542.

7. La CC, Smith SA, Kalathottukaren MT, Haynes CA, Morrissey JH, Kizhakkedathu JN. External Trigger Free Charge Switchable Cationic Ligands in the Design of Safe and Effective Universal Heparin Antidote. Adv Healthc Mater. 2024 Mar 27:e2400108. doi: 10.1002/adhm.202400108. Epub ahead of print. PMID: 38537246.

March 25, Pubcrawler Hits:

1. Fang S, Chang KW, Lefebvre L. Roles of endogenous retroviral elements in the establishment and maintenance of imprinted gene expression. Front Cell Dev Biol. 2024 Mar 5;12:1369751. doi: 10.3389/fcell.2024.1369751. PMID: 38505259; PMCID: PMC10948482.

2. Torres V, Contreras V, Gutiérrez B, San Francisco J, Catalán A, Vega JL, Moon KM, Foster LJ, de Almeida RF, Kalergis AM, González J. Oral infectivity through carnivorism in murine model of Trypanosoma cruzi infection. Front Cell Infect Microbiol. 2024 Feb 22;14:1297099. doi: 10.3389/fcimb.2024.1297099. PMID: 38495650; PMCID: PMC10941204.

3. Luo HD, Moon H, Siren E, Clark M, Drayton M, Kizhakkedathu JN. Investigation on Adaptability and Applicability of Polymer-Mediated Cell Surface Engineering by Ligation with Transglutaminase. ACS Appl Mater Interfaces. 2024 Mar 21. doi: 10.1021/acsami.3c19202. Epub ahead of print. PMID: 38512725.

March 18, Pubcrawler Hits:

1. Bakhireva LN, Solomon E, Roberts MH, Ma X, Rai R, Wiesel A, Jacobson SW, Weinberg J, Milligan ED. Independent and Combined Effects of Prenatal Alcohol Exposure and Prenatal Stress on Fetal HPA Axis Development. Int J Mol Sci. 2024 Feb 26;25(5):2690. doi: 10.3390/ijms25052690. PMID: 38473937; PMCID: PMC10932119.

2. Shapira T, Christofferson M, Av-Gay Y. The antimicrobial activity of innate host-directed therapies - a systematic review. Int J Antimicrob Agents. 2024 Mar 13:107138. doi: 10.1016/j.ijantimicag.2024.107138. Epub ahead of print. PMID: 38490573.

3. Zhao Z, Young JW, Duong van Hoa F. Affinity Purification of Membrane β-Barrel Proteins via Biotin-Tagged Peptidiscs. Methods Mol Biol. 2024;2778:147-158. doi: 10.1007/978-1-0716-3734-0_10. PMID: 38478277.

March 11, Pubcrawler Hits:

1. Francia V, Zhang Y, Cheng MHY, Schiffelers RM, Witzigmann D, Cullis PR. A magnetic separation method for isolating and characterizing the biomolecular corona of lipid nanoparticles. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307803120. doi: 10.1073/pnas.2307803120. Epub 2024 Mar 4. PMID: 38437542.

2. Matsell E, Andersen JP, Molday RS. Functional and In-silico analysis of ATP8A2 and other P4-ATPase variants associated with human genetic diseases. Dis Model Mech. 2024 Mar 4:dmm.050546. doi: 10.1242/dmm.050546. Epub ahead of print. PMID: 38436085.

3. Hoang KL, Read TD, King KC. Incomplete immunity in a natural animal-microbiota interaction selects for higher pathogen virulence. Curr Biol. 2024 Feb 23:S0960-9822(24)00157-X. doi: 10.1016/j.cub.2024.02.015. Epub ahead of print. PMID: 38430909.

March 4, Pubcrawler Hits:

1. Choy WH, Adler A, Morgan-Lang C, Gough EK, Hallam SJ, Manges AR, Chew BH, Penniston K, Miller A, Lange D. Deficient butyrate metabolism in the intestinal microbiome is a potential risk factor for recurrent kidney stone disease. Urolithiasis. 2024 Feb 28;52(1):38. doi: 10.1007/s00240-024-01534-x. PMID: 38413462.

2. Gao E, Brown JAR, Jung S, Howe LJ. A fluorescent assay for cryptic transcription in Saccharomyces cerevisiae reveals novel insights into factors that stabilize chromatin structure on newly replicated DNA. Genetics. 2024 Feb 26:iyae016. doi: 10.1093/genetics/iyae016. Epub ahead of print. PMID: 38407959.

3. Loutet SA, Cheung S, Zaytsoff S, Hofacre C, Jones MK, Van Petegem F, Abnousi H. Research Note: Clostridium perfringens NetB and CnaA neutralizing nanobodies in feed reduce the incidence of poultry necrotic enteritis. Poult Sci. 2024 Feb 22;103(4):103578. doi: 10.1016/j.psj.2024.103578. Epub ahead of print. PMID: 38417327.

4. Cherian CM, Reeves HR, De Silva D, Tsao S, Marshall KE, Rideout EJ. Consideration of sex as a biological variable in diabetes research across twenty years. Biol Sex Differ. 2024 Feb 26;15(1):19. doi: 10.1186/s13293-024-00595-2. PMID: 38409052; PMCID: PMC10895746.

5. Li FKK, Worrall LJ, Gale RT, Brown ED, Strynadka NCJ. Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Sci Adv. 2024 Mar;10(9):eadj3864. doi: 10.1126/sciadv.adj3864. Epub 2024 Feb 28. PMID: 38416829; PMCID: PMC10901376.

6. McLean MA, Weinberg J, Synnes AR, Miller SP, Grunau RE. Relationships between cortisol levels across early childhood and processing speed at age 4.5 years in children born very preterm. Child Neuropsychol. 2024 Feb 26:1-19. doi: 10.1080/09297049.2024.2314958. Epub ahead of print. PMID: 38406870.

7. Kapustina M, Zhang AA, Tsai JYJ, Bristow BN, Kraus L, Sullivan KE, Erwin SR, Wang L, Stach TR, Clements J, Lemire AL, Cembrowski MS. The cell-type-specific spatial organization of the anterior thalamic nuclei of the mouse brain. Cell Rep. 2024 Feb 29;43(3):113842. doi: 10.1016/j.celrep.2024.113842. Epub ahead of print. PMID: 38427564.

8. Lapcik P, Stacey RG, Potesil D, Kulhanek P, Foster LJ, Bouchal P. Global interactome mapping reveals pro-tumorigenic interactions of NF-κB in breast cancer. Mol Cell Proteomics. 2024 Feb 26:100744. doi: 10.1016/j.mcpro.2024.100744. Epub ahead of print. PMID: 38417630.

9. Foster LJ, Tsvetkov N, McAfee A. Mechanisms of pathogen and pesticide resistance in honey bees. Physiology (Bethesda). 2024 Feb 27. doi: 10.1152/physiol.00033.2023. Epub ahead of print. PMID: 38411571.

February 26, Pubcrawler Hits:

1. Strilchuk AW, Hur WS, Batty P, Sang Y, Abrahams SR, Yong ASM, Leung J, Silva LM, Schroeder JA, Nesbitt K, de Laat B, Moutsopoulos NM, Bugge TH, Shi Q, Cullis PR, Merricks EP, Wolberg AS, Flick MJ, Lillicrap D, Nichols TC, Kastrup CJ. Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A. Sci Transl Med. 2024 Feb 21;16(735):eadh0027. doi: 10.1126/scitranslmed.adh0027. Epub 2024 Feb 21. PMID: 38381848.

2. Hsing V, Zhao HQ, Post M, Devine D, McVey MJ. Preservation of Recipient Plasma Sphingosine-1-Phosphate Levels Reduces Transfusion-related Acute Lung Injury. Am J Physiol Lung Cell Mol Physiol. 2024 Feb 20. doi: 10.1152/ajplung.00388.2023. Epub ahead of print. PMID: 38375568.

3. Wolf ME, Lalande AT, Newman BL, Bleem AC, Palumbo CT, Beckham GT, Eltis LD. The catabolism of lignin-derived p-methoxylated aromatic compounds by Rhodococcus jostii RHA1. Appl Environ Microbiol. 2024 Feb 21:e0215523. doi: 10.1128/aem.02155-23. Epub ahead of print. PMID: 38380926.

4. Asghari P, Scriven DRL, Shahrasebi S, Valdivia HH, Alsina KM, Valdivia CR, Navarro-Garcia JA, Wehrens XHT, Moore EDW. Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. J Gen Physiol. 2024 Apr 1;156(4):e202213108. doi: 10.1085/jgp.202213108. Epub 2024 Feb 22. PMID: 38385988; PMCID: PMC10883851.

5. Frenz-Wiessner S, Fairley SD, Buser M, Goek I, Salewskij K, Jonsson G, Illig D, Zu Putlitz B, Petersheim D, Li Y, Chen PH, Kalauz M, Conca R, Sterr M, Geuder J, Mizoguchi Y, Megens RTA, Linder MI, Kotlarz D, Rudelius M, Penninger JM, Marr C, Klein C. Generation of complex bone marrow organoids from human induced pluripotent stem cells. Nat Methods. 2024 Feb 19. doi: 10.1038/s41592-024-02172-2. Epub ahead of print. PMID: 38374263.

February 19, Pubcrawler Hits:

1. S Mesquita F, Abrami L, Linder ME, Bamji SX, Dickinson BC, van der Goot FG. Mechanisms and functions of protein S-acylation. Nat Rev Mol Cell Biol. 2024 Feb 14. doi: 10.1038/s41580-024-00700-8. Epub ahead of print. PMID: 38355760.

2. Ewald JD, Zhou G, Lu Y, Kolic J, Ellis C, Johnson JD, Macdonald PE, Xia J. Web-based multi-omics integration using the Analyst software suite. Nat Protoc. 2024 Feb 14. doi: 10.1038/s41596-023-00950-4. Epub ahead of print. PMID: 38355833.

3. Pett N, Hunter M, Carranza García NA, Seo JH, Collins SR, Rohwer F, Osborne LC, Tropini C. T4 Bacteriophage and E. coli Interaction in the Murine Intestine: A Prototypical Model for Studying Host-Bacteriophage Dynamics In Vivo. J Vis Exp. 2024 Jan 26;(203). doi: 10.3791/65906. PMID: 38345223.

4. Le T, Ferling I, Qiu L, Nabaile C, Assunção L, Roskelley CD, Grinstein S, Freeman SA. Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells. Dev Cell. 2024 Feb 9:S1534-5807(24)00040-6. doi: 10.1016/j.devcel.2024.01.020. Epub ahead of print. PMID: 38359833.

5. Diao J, Yip CK, Zhong Q. Molecular structures and function of the autophagosome-lysosome fusion machinery. Autophagy Rep. 2024;3(1):2305594. doi: 10.1080/27694127.2024.2305594. Epub 2024 Feb 4. PMID: 38344192; PMCID: PMC10852212.

6. Quintard C, Tubbs E, Jonsson G, Jiao J, Wang J, Werschler N, Laporte C, Pitaval A, Bah TS, Pomeranz G, Bissardon C, Kaal J, Leopoldi A, Long DA, Blandin P, Achard JL, Battail C, Hagelkruys A, Navarro F, Fouillet Y, Penninger JM, Gidrol X. A microfluidic platform integrating functional vascularized organoids-on-chip. Nat Commun. 2024 Feb 16;15(1):1452. doi: 10.1038/s41467-024-45710-4. PMID: 38365780; PMCID: PMC10873332.

February 12, Pubcrawler Hits:

1. Zhao B, Kamanzi A, Zhang Y, Chan KYT, Robertson M, Leslie S, Cullis PR. Determination of the interior pH of lipid nanoparticles using a pH-sensitive fluorescent dye-based DNA probe. Biosens Bioelectron. 2024 Jan 24;251:116065. doi: 10.1016/j.bios.2024.116065. Epub ahead of print. PMID: 38330772.

2. Horvath RM, Brumme ZL, Sadowski I. Small molecule inhibitors of transcriptional cyclin-dependent kinases impose HIV-1 latency, presenting "block and lock" treatment strategies. Antimicrob Agents Chemother. 2024 Feb 6:e0107223. doi: 10.1128/aac.01072-23. Epub ahead of print. PMID: 38319085.

February 5, Pubcrawler Hits:

1. Fedida D, Sastre D, Dou Y, Westhoff M, Eldstrom J. Evaluating sequential and allosteric activation models in IKs channels with mutated voltage sensors. J Gen Physiol. 2024 Mar 4;156(3):e202313465. doi: 10.1085/jgp.202313465. Epub 2024 Jan 31. PMID: 38294435; PMCID: PMC10829594.

2. Alsouri S, Ambrose A, Mougios N, Paglilla N, Mayr F, Choi K, Loeber J, Chapuy B, Haeupl B, Opazo F, Oellerich T, Gold M, Engelke M. Actinin-4 controls survival signaling in B cells by limiting the lateral mobility of B-cell antigen receptors. Eur J Immunol. 2024 Feb 1:e2350774. doi: 10.1002/eji.202350774. Epub ahead of print. PMID: 38299456.

3. Dunn SE, Correale J, Gommerman JL, Horwitz MS. Editorial: Environmental factors in autoimmunity. Front Immunol. 2024 Jan 16;14:1361884. doi: 10.3389/fimmu.2023.1361884. PMID: 38292480; PMCID: PMC10824893.

4. Strawn G, Wong RWK, Young BP, Davey M, Nislow C, Conibear E, Loewen CJR, Mayor T. Genome-wide screen identifies new set of genes for improved heterologous laccase expression in Saccharomyces cerevisiae. Microb Cell Fact. 2024 Jan 29;23(1):36. doi: 10.1186/s12934-024-02298-0. PMID: 38287338; PMCID: PMC10823697.

5. Babini H, Jiménez-Sábado V, Stogova E, Arslanova A, Butt M, Dababneh S, Asghari P, Moore EDW, Claydon TW, Chiamvimonvat N, Hove-Madsen L, Tibbits GF. hiPSC-derived cardiomyocytes as a model to study the role of small-conductance Ca2+-activated K+ (SK) ion channel variants associated with atrial fibrillation. Front Cell Dev Biol. 2024 Jan 18;12:1298007. doi: 10.3389/fcell.2024.1298007. PMID: 38304423; PMCID: PMC10830749.

6. Holani R, Littlejohn PT, Edwards K, Petersen C, Moon KM, Stacey RG, Bozorgmehr T, Gerbec ZJ, Serapio-Palacios A, Krekhno Z, Donald K, Foster LJ, Turvey SE, Finlay BB. A murine model of maternal micronutrient deficiencies and gut inflammatory host-microbe interactions in the offspring. Cell Mol Gastroenterol Hepatol. 2024 Jan 31:S2352-345X(24)00021-3. doi: 10.1016/j.jcmgh.2024.01.018. Epub ahead of print. PMID: 38307490.

January 29, Pubcrawler Hits:

1. McAfee A, Chapman A, Bao G, Tarpy DR, Foster LJ. Investigating trade-offs between ovary activation and immune protein expression in bumble bee (Bombus impatiens) workers and queens. Proc Biol Sci. 2024 Jan 31;291(2015):20232463. doi: 10.1098/rspb.2023.2463. Epub 2024 Jan 24. PMID: 38264776; PMCID: PMC10806398.

2. Caesar L, Rice DW, McAfee A, Underwood R, Ganote C, Tarpy DR, Foster LJ, Newton ILG. Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages. mSystems. 2024 Jan 23:e0118223. doi: 10.1128/msystems.01182-23. Epub ahead of print. PMID: 38259099.

January 22, Pubcrawler Hits:

1. Omenn GS, Lane L, Overall CM, Lindskog C, Pineau C, Packer NH, Cristea IM, Weintraub ST, Orchard S, Roehrl MHA, Nice E, Guo T, Van Eyk JE, Liu S, Bandeira N, Aebersold R, Moritz RL, Deutsch EW. The 2023 Report on the Proteome from the HUPO Human Proteome Project. J Proteome Res. 2024 Jan 17. doi: 10.1021/acs.jproteome.3c00591. Epub ahead of print. PMID: 38232391.

2. Fleck SA, Biswas P, DeWitt ED, Knuteson RL, Eisman RC, Nemkov T, D'Alessandro A, Tennessen JM, Rideout E, Weaver LN. Auxin exposure disrupts feeding behavior and fatty acid metabolism in adult Drosophila. Elife. 2024 Jan 19;12:RP91953. doi: 10.7554/eLife.91953. PMID: 38240746.

3. Cikes D, Leutner M, Cronin SJF, Novatchkova M, Pfleger L, Klepochová R, Lair B, Lac M, Bergoglio C, Viguerie N, Dürnberger G, Roitinger E, Grivej M, Rullman E, Gustafsson T, Hagelkruys A, Tavernier G, Bourlier V, Knauf C, Krebs M, Kautzky-Willer A, Moro C, Krssak M, Orthofer M, Penninger JM. Gpcpd1-GPC metabolic pathway is dysfunctional in aging and its deficiency severely perturbs glucose metabolism. Nat Aging. 2024 Jan;4(1):80-94. doi: 10.1038/s43587-023-00551-6. Epub 2024 Jan 18. PMID: 38238601.

4. Hayes RS, Oraby AK, Camargo C, Marchant DJ, Sagan SM. Mapping respiratory syncytial virus fusion protein interactions with the receptor IGF1R and the impact of alanine-scanning mutagenesis on viral infection. J Gen Virol. 2024 Jan;105(1). doi: 10.1099/jgv.0.001951. PMID: 38231539.

5. Antony F, Brough Z, Zhao Z, Duong van Hoa F. Capture of the Mouse Organ Membrane Proteome Specificity in Peptidisc Libraries. J Proteome Res. 2024 Jan 17. doi: 10.1021/acs.jproteome.3c00825. Epub ahead of print. PMID: 38232390.

January 15, Pubcrawler Hits:

1. Brassard J, Hughes MR, Dean P, Hernaez DC, Thornton S, Banville AC, Smazynski J, Warren M, Zhang K, Milne K, Gilks CB, Mes-Masson AM, Huntsman DG, Nelson BH, Roskelley CD, McNagny KM. A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma. Front Oncol. 2023 Dec 21;13:1286754. doi: 10.3389/fonc.2023.1286754. PMID: 38188285; PMCID: PMC10771318.

January 8, Pubcrawler Hits:

1. Fernandes VM, Auld V, Klämbt C. Glia as Functional Barriers and Signaling Intermediaries. Cold Spring Harb Perspect Biol. 2024 Jan 2;16(1):a041423. doi: 10.1101/cshperspect.a041423. PMID: 38167424; PMCID: PMC10759988.

2. Mills DB, Simister RL, Sehein TR, Hallam SJ, Sperling EA, Crowe SA. Constraining the oxygen requirements for modern microbial eukaryote diversity. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2303754120. doi: 10.1073/pnas.2303754120. Epub 2024 Jan 2. PMID: 38165897.

3. Iworima DG, Baker RK, Ellis C, Sherwood C, Zhan L, Rezania A, Piret JM, Kieffer TJ. Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells. Stem Cell Res Ther. 2024 Jan 2;15(1):1. doi: 10.1186/s13287-023-03574-3. PMID: 38167219; PMCID: PMC10762849.


December 26, Pubcrawler Hits:

1. Peeters SB, Posynick BJ, Brown CJ. Out of the Silence: Insights into How Genes Escape X-Chromosome Inactivation. Epigenomes. 2023 Nov 23;7(4):29. doi: 10.3390/epigenomes7040029. PMID: 38131901; PMCID: PMC10742877.

2. Sheffield WP, Singh K, Beckett A, Devine DV. Prehospital Freeze-Dried Plasma in Trauma: A Critical Review. Transfus Med Rev. 2023 Nov 30;38(1):150807. doi: 10.1016/j.tmrv.2023.150807. Epub ahead of print. PMID: 38114340.

3. Iworima DG, Baker RK, Piret JM, Kieffer TJ. Analysis of the effects of bench-scale cell culture platforms and inoculum cell concentrations on PSC aggregate formation and culture. Front Bioeng Biotechnol. 2023 Dec 1;11:1267007. doi: 10.3389/fbioe.2023.1267007. PMID: 38107616; PMCID: PMC10722899.

4. Burckhardt JC, Tropini C. Inoviruses. Curr Biol. 2023 Dec 18;33(24):R1272-R1274. doi: 10.1016/j.cub.2023.10.036. PMID: 38113833.

5. Bar-Yoseph H, Krekhno Z, Cirstea M, Holani R, Moon KM, Foster LJ, Wieck M, Piper HG, Finlay BB. The effect of nutrient deprivation on early life small intestinal mucosal microbiome and host proteome. J Nutr. 2023 Dec 16:S0022-3166(23)72809-5. doi: 10.1016/j.tjnut.2023.12.020. Epub ahead of print. PMID: 38110179.

6. Skinnider MA, Akinlaja MO, Foster LJ. Mapping protein states and interactions across the tree of life with co-fractionation mass spectrometry. Nat Commun. 2023 Dec 15;14(1):8365. doi: 10.1038/s41467-023-44139-5. PMID: 38102123; PMCID: PMC10724252.

7. Xu MR, Liao ZY, Brock JR, Du K, Li GY, Chen ZQ, Wang YH, Gao ZN, Agarwal G, Wei KH, Shao F, Pang S, Platts AE, van de Velde J, Lin HM, Teresi SJ, Bird K, Niederhuth CE, Xu JG, Yu GH, Yang JY, Dai SF, Nelson A, Braasch I, Zhang XG, Schartl M, Edger PP, Han MJ, Zhang HH. Maternal dominance contributes to subgenome differentiation in allopolyploid fishes. Nat Commun. 2023 Dec 15;14(1):8357. doi: 10.1038/s41467-023-43740-y. PMID: 38102128; PMCID: PMC10724154.

December 18, Pubcrawler Hits:

1. Meulewaeter S, Zhang Y, Wadhwa A, Fox K, Lentacker I, Harder KW, Cullis PR, De Smedt SC, H Y Cheng M, Verbeke R. Considerations on the design of lipid-based mRNA vaccines against cancer. J Mol Biol. 2023 Dec 6:168385. doi: 10.1016/j.jmb.2023.168385. Epub ahead of print. PMID: 38065276.

2. Richardson-Sanchez T, Chan ACK, Sabatino B, Lin H, Gaynor EC, Murphy MEP. Dissecting components of the Campylobacter jejuni fetMP-fetABCDEF gene cluster under iron limitation. Microbiol Spectr. 2023 Dec 14:e0314823. doi: 10.1128/spectrum.03148-23. Epub ahead of print. PMID: 38096459.

3. Bedi A, Choi K, Keane C, Bolger-Munro M, Ambrose AR, Gold MR. WAVE2 Regulates Actin-Dependent Processes Induced by the B Cell Antigen Receptor and Integrins. Cells. 2023 Nov 25;12(23):2704. doi: 10.3390/cells12232704. PMID: 38067132; PMCID: PMC10705906.

4. Hsu CR, Sangha G, Fan W, Zheng J, Sugioka K. Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis. Nat Commun. 2023 Dec 8;14(1):8138. doi: 10.1038/s41467-023-43996-4. PMID: 38065974; PMCID: PMC10709429.

5. Bharat TAM, Tocheva EI, Alva V. The cell envelope architecture of Deinococcus: HPI forms the S-layer and SlpA tethers the outer membrane to peptidoglycan. Proc Natl Acad Sci U S A. 2023 Dec 19;120(51):e2305338120. doi: 10.1073/pnas.2305338120. Epub 2023 Dec 12. PMID: 38085775.

6. Moradimotlagh A, Chen S, Koohbor S, Moon KM, Foster LJ, Reiner N, Nandan D. Leishmania infection upregulates and engages host macrophage Argonaute 1, and system-wide proteomics reveals Argonaute 1-dependent host response. Front Immunol. 2023 Nov 30;14:1287539. doi: 10.3389/fimmu.2023.1287539. PMID: 38098491; PMCID: PMC10720368.

7. Abbasi U, Abbina S, Gill A, Kizhakkedathu JN. Development of an iron overload HepG2 cell model using ferrous ammonium citrate. Sci Rep. 2023 Dec 8;13(1):21915. doi: 10.1038/s41598-023-49072-7. PMID: 38081916; PMCID: PMC10713717.

8. Chen MY, Haney CH. It takes a plant village to raise a microbiome. Cell Host Microbe. 2023 Dec 13;31(12):1956-1958. doi: 10.1016/j.chom.2023.11.009. PMID: 38096789.

9. Rosin JM, Tremblay MÈ, Plemel JR. Editorial: Insights in non-neuronal cells: 2022. Front Cell Neurosci. 2023 Nov 28;17:1332869. doi: 10.3389/fncel.2023.1332869. PMID: 38089146; PMCID: PMC10715240.

December 11, Pubcrawler Hits:

1. Benedet PO, Safikhan NS, Pereira MJ, Lum BM, Botezelli JD, Kuo CH, Wu HL, Craddock BP, Miller WT, Eriksson JW, Yue JTY, Conway EM. CD248 promotes insulin resistance by binding to the insulin receptor and dampening its insulin-induced autophosphorylation. EBioMedicine. 2023 Dec 6;99:104906. doi: 10.1016/j.ebiom.2023.104906. Epub ahead of print. PMID: 38061240.

2. Allais L, Thibodeau B, Khan NS, Crowe SA, Cannicci S, Not C. Salinity, mineralogy, porosity, and hydrodynamics as drivers of carbon burial in urban mangroves from a megacity. Sci Total Environ. 2023 Dec 4:168955. doi: 10.1016/j.scitotenv.2023.168955. Epub ahead of print. PMID: 38056642.

3. Uy RJ, Serrano K, Hadjesfandiari N, Shih AW, Devine D. The effects of pen ink and surface disinfectants on red blood cells stored in plasticized polyvinylchloride transfusion bags. Transfusion. 2023 Dec 7. doi: 10.1111/trf.17620. Epub ahead of print. PMID: 38059437.

4. Brown KL, Krekhno JMC, Xing S, Huan T, Eltis LD. Cholesterol-Mediated Coenzyme A Depletion in Catabolic Mutants of Mycobacteria Leads to Toxicity. ACS Infect Dis. 2023 Dec 6. doi: 10.1021/acsinfecdis.3c00237. Epub ahead of print. PMID: 38054469.

5. Bixby M, Cunningham M, Foster L, Higo H, Morfin N. British Columbia beekeeping revenues and costs: survey data and profit modeling. J Insect Sci. 2023 Nov 1;23(6):22. doi: 10.1093/jisesa/iead070. PMID: 38055942.

6. Wang F, Pasin D, Skinnider MA, Liigand J, Kleis JN, Brown D, Oler E, Sajed T, Gautam V, Harrison S, Greiner R, Foster LJ, Dalsgaard PW, Wishart DS. Deep Learning-Enabled MS/MS Spectrum Prediction Facilitates Automated Identification Of Novel Psychoactive Substances. Anal Chem. 2023 Dec 4. doi: 10.1021/acs.analchem.3c02413. Epub ahead of print. PMID: 38048435.

December 4, Pubcrawler Hits:

1. Leung J, Strong C, Badior KE, Robertson M, Wu X, Meledeo MA, Kang E, Paul M, Sato Y, Harashima H, Cap AP, Devine DV, Jan E, Cullis PR, Kastrup CJ. Genetically engineered transfusable platelets using mRNA lipid nanoparticles. Sci Adv. 2023 Dec;9(48):eadi0508. doi: 10.1126/sciadv.adi0508. Epub 2023 Dec 1. PMID: 38039367; PMCID: PMC10691771.

2. Toews JNC, Philippe TJ, Dordevic M, Hill LA, Hammond GL, Viau V. Corticosteroid-binding globulin (SERPINA6) consolidates sexual dimorphism of adult rat liver. Endocrinology. 2023 Nov 28:bqad179. doi: 10.1210/endocr/bqad179. Epub ahead of print. PMID: 38015819.

3. Keymeulen B, De Groot K, Jacobs-Tulleneers-Thevissen D, Thompson DM, Bellin MD, Kroon EJ, Daniels M, Wang R, Jaiman M, Kieffer TJ, Foyt HL, Pipeleers D. Encapsulated stem cell-derived β cells exert glucose control in patients with type 1 diabetes. Nat Biotechnol. 2023 Nov 27. doi: 10.1038/s41587-023-02055-5. Epub ahead of print. PMID: 38012450.

4. Zhang Y, Asghari P, Scriven DRL, Moore EDW, Chou KC. 3D structured illumination microscope using a spinning disk [Invited]. Biomed Opt Express. 2023 Oct 11;14(11):5710-5719. doi: 10.1364/BOE.499181. PMID: 38021136; PMCID: PMC10659796.

5. Elahi MM, Witt AN, Pryzdial ELG, McBeth PB. Thrombotic triad in microgravity. Thromb Res. 2023 Nov 22;233:82-87. doi: 10.1016/j.thromres.2023.11.020. Epub ahead of print. PMID: 38029549.

November 27, Pubcrawler Hits:

1. Falkenhain K, Oliveira BF, Islam H, Neudorf H, Cen HH, Johnson JD, Madden K, Singer J, Walsh JJ, Little JP. The effect of acute and 14-day exogenous ketone supplementation on glycaemic control in adults with type 2 diabetes: two randomized controlled trials. Am J Physiol Endocrinol Metab. 2023 Nov 22. doi: 10.1152/ajpendo.00332.2023. Epub ahead of print. PMID: 37991451.

November 20, Pubcrawler Hits:

1. Kolic J, Sun WG, Johnson JD, Guess N. Amino acid-stimulated insulin secretion: a path forward in type 2 diabetes. Amino Acids. 2023 Nov 15. doi: 10.1007/s00726-023-03352-8. Epub ahead of print. PMID: 37966501.

2. Morales LD, Av-Gay Y, Murphy MEP. Acidic pH modulates Burkholderia cenocepacia antimicrobial susceptibility in the cystic fibrosis nutritional environment. Microbiol Spectr. 2023 Nov 15:e0273123. doi: 10.1128/spectrum.02731-23. Epub ahead of print. PMID: 37966209.

3. Tropini C, Finlay BB, Nichter M, Melby MK, Metcalf JL, Dominguez-Bello MG, Zhao L, McFall-Ngai MJ, Geva-Zatorsky N, Amato KR, Undurraga EA, Poinar HN, Gilbert JA. Time to rethink academic publishing: the peer reviewer crisis. mBio. 2023 Nov 17:e0109123. doi: 10.1128/mbio.01091-23. Epub ahead of print. PMID: 37975666.

4. Skinnider MA, Mérette SAM, Pasin D, Rogalski J, Foster LJ, Scheuermeyer F, Shapiro AM. Identification of Emerging Novel Psychoactive Substances by Retrospective Analysis of Population-Scale Mass Spectrometry Data Sets. Anal Chem. 2023 Nov 15. doi: 10.1021/acs.analchem.3c03451. Epub ahead of print. PMID: 37966487.

November 13, Pubcrawler Hits:

1. Uzel A, Agiotis L, Baron A, Zhigaltsev IV, Cullis PR, Hasanzadeh Kafshgari M, Meunier M. Single Pulse Nanosecond Laser-Stimulated Targeted Delivery of Anti-Cancer Drugs from Hybrid Lipid Nanoparticles Containing 5 nm Gold Nanoparticles. Small. 2023 Nov 7:e2305591. doi: 10.1002/smll.202305591. Epub ahead of print. PMID: 37936336.

2. Cardoen B, Vandevoorde KR, Gao G, Ortiz-Silva M, Alan P, Liu W, Tiliakou E, Vogl AW, Hamarneh G, Nabi IR. Membrane contact site detection (MCS-DETECT) reveals dual control of rough mitochondria-ER contacts. J Cell Biol. 2024 Jan 1;223(1):e202206109. doi: 10.1083/jcb.202206109. Epub 2023 Nov 10. PMID: 37948126; PMCID: PMC10638097.

November 6, Pubcrawler Hits:

1. Bolsoni J, Liu D, Mohabatpour F, Ebner R, Sadhnani G, Tafech B, Leung J, Shanta S, An K, Morin T, Chen Y, Arguello A, Choate K, Jan E, Ross CJD, Brambilla D, Witzigmann D, Kulkarni J, Cullis PR, Hedtrich S. Lipid Nanoparticle-Mediated Hit-and-Run Approaches Yield Efficient and Safe In Situ Gene Editing in Human Skin. ACS Nano. 2023 Nov 2. doi: 10.1021/acsnano.3c08644. Epub ahead of print. PMID: 37918441.

2. Zhang AMY, Xia YH, Lin JSH, Chu KH, Wang WCK, Ruiter TJJ, Yang JCC, Chen N, Chhuor J, Patil S, Cen HH, Rideout EJ, Richard VR, Schaeffer DF, Zahedi RP, Borchers CH, Johnson JD, Kopp JL. Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation. Cell Metab. 2023 Oct 26:S1550-4131(23)00372-8. doi: 10.1016/j.cmet.2023.10.003. Epub ahead of print. PMID: 37913768.

3. Ho KYL, An K, Carr RL, Dvoskin AD, Ou AYJ, Vogl W, Tanentzapf G. Maintenance of hematopoietic stem cell niche homeostasis requires gap junction-mediated calcium signaling. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2303018120. doi: 10.1073/pnas.2303018120. Epub 2023 Oct 30. PMID: 37903259.

4. Hentrich L, Parnes M, Lotze TE, Coorg R, de Koning TJ, Nguyen KM, Yip CK, Jungbluth H, Koy A, Dafsari HS. Novel Genetic and Phenotypic Expansion in GOSR2-Related Progressive Myoclonus Epilepsy. Genes (Basel). 2023 Sep 25;14(10):1860. doi: 10.3390/genes14101860. PMID: 37895210; PMCID: PMC10606070.

5. Kondegowda NG, Filipowska J, Do JS, Leon-Rivera N, Li R, Hampton R, Ogyaadu S, Levister C, Penninger JM, Reijonen H, Levy CJ, Vasavada RC. RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes. Sci Adv. 2023 Nov 3;9(44):eadf5238. doi: 10.1126/sciadv.adf5238. Epub 2023 Nov 1. PMID: 37910614; PMCID: PMC10619938.

6. Wang K, Khoramjoo M, Srinivasan K, Gordon PMK, Mandal R, Jackson D, Sligl W, Grant MB, Penninger JM, Borchers CH, Wishart DS, Prasad V, Oudit GY. Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID. Cell Rep Med. 2023 Oct 18:101254. doi: 10.1016/j.xcrm.2023.101254. Epub ahead of print. PMID: 37890487.

October 29, Pubcrawler Hits:

1. McDaniel EA, Scarborough M, Mulat DG, Lin X, Sampara PS, Olson HM, Young RP, Eder EK, Attah IK, Markillie LM, Hoyt DW, Lipton MS, Hallam SJ, Ziels RM. Diverse electron carriers drive syntrophic interactions in an enriched anaerobic acetate-oxidizing consortium. ISME J. 2023 Oct 25. doi: 10.1038/s41396-023-01542-6. Epub ahead of print. PMID: 37880541.

2. Colombo É, Désilets A, Hassanzadeh M, Lemieux G, Marois I, Cliche D, Delbrouck JA, Murza A, Jean F, Marsault E, Richter MV, Leduc R, Boudreault PL. Optimization of ketobenzothiazole-based type II transmembrane serine protease inhibitors to block H1N1 influenza virus replication. ChemMedChem. 2023 Oct 21:e202300458. doi: 10.1002/cmdc.202300458. Epub ahead of print. PMID: 37864572.

3. Ben-Eltriki M, Ahmadi AR, Nakao Y, Golla K, Lakschevitz F, Häkkinen L, Granville DJ, Kim H. Granzyme B promotes matrix metalloproteinase-1 (MMP-1) release from gingival fibroblasts in a PAR1- and Erk1/2-dependent manner: A novel role in periodontal inflammation. J Periodontal Res. 2023 Oct 24. doi: 10.1111/jre.13190. Epub ahead of print. PMID: 37873693.

4. Monteil V, Kwon H, John L, Salata C, Jonsson G, Vorrink SU, Appelberg S, Youhanna S, Dyczynski M, Leopoldi A, Leeb N, Volz J, Hagelkruys A, Kellner MJ, Devignot S, Michlits G, Foong-Sobis M, Weber F, Lauschke VM, Horn M, Feldmann H, Elling U, Penninger JM, Mirazimi A. Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections. Nat Commun. 2023 Oct 25;14(1):6785. doi: 10.1038/s41467-023-42526-6. PMID: 37880247; PMCID: PMC10600203.

October 23, Pubcrawler Hits:

1. Graff P, Woerz D, Wilzopolski J, Voss A, Sarrazin J, Blimkie TM, Weiner J 3rd, Kershaw O, Panwar P, Hackett T, Lau S, Brömme D, Beule D, Lee YA, Hancock REW, Gruber AD, Bäumer W, Hedtrich S. EXTRACELLULAR MATRIX REMODELING IN ATOPIC DERMATITIS HARNESSES THE ONSET OF AN ASTHMATIC PHENOTYPE AND IS A POTENTIAL CONTRIBUTOR TO THE ATOPIC MARCH. J Invest Dermatol. 2023 Oct 12:S0022-202X(23)02965-2. doi: 10.1016/j.jid.2023.09.278. Epub ahead of print. PMID: 37838332.

2. Zusman EZ, Chau CMY, Bone JN, Hookenson K, Brain U, Glier MB, Grunau RE, Weinberg J, Devlin AM, Oberlander TF. Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study. Dev Psychobiol. 2023 Nov;65(7):e22425. doi: 10.1002/dev.22425. PMID: 37860904.

3. Turgu B, El-Naggar A, Kogler M, Tortola L, Zhang HF, Hassan M, Lizardo MM, Kung SH, Lam W, Penninger JM, Sorensen PH. The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes. EMBO Rep. 2023 Oct 17:e56815. doi: 10.15252/embr.202356815. Epub ahead of print. PMID: 37846480.

4. Hagman JR, Rahfeld P, Withers SG, Kizhakkedathu JN, Olsson ML, Storry JR. Use of a recombinant deacetylase to convert A1 red blood cells to the acquired B phenotype for quality control purposes. Blood Transfus. 2023 Sep 20. doi: 10.2450/BloodTransfus.584. Epub ahead of print. PMID: 37847210.

October 16, Pubcrawler Hits:

1. Lu J, Karkouti K, Peer M, Englesakis M, Spinella PC, Apelseth TO, Scorer TG, Kahr WHA, McVey M, Rao V, Abrahamyan L, Lieberman L, Mewhort H, Devine DV, Callum J, Bartoszko J. Cold-stored platelets for acute bleeding in cardiac surgical patients: a narrative review. Can J Anaesth. 2023 Oct 13. English. doi: 10.1007/s12630-023-02561-9. Epub ahead of print. PMID: 37831350.

2. Coates-Park S, Lazaroff C, Gurung S, Rich J, Colladay A, O'Neill M, Butler GS, Overall CM, Stetler-Stevenson WG, Peeney D. Tissue Inhibitors of Metalloproteinases are proteolytic targets of Matrix Metalloproteinase 9. Matrix Biol. 2023 Oct 5:S0945-053X(23)00103-8. doi: 10.1016/j.matbio.2023.09.002. Epub ahead of print. PMID: 37804930.

October 9, Pubcrawler Hits:

1. Ågren MS, Hinz B, Kalogeropoulos K, Overall CM, Smola H, Werner S. Ulrich auf dem Keller (1974-2023). Wound Repair Regen. 2023 Sep 20. doi: 10.1111/wrr.13118. Epub ahead of print. PMID: 37735982.

2. Fine JD, Foster LJ, McAfee A. Indirect exposure to insect growth disruptors affects honey bee (Apis mellifera) reproductive behaviors and ovarian protein expression. PLoS One. 2023 Oct 2;18(10):e0292176. doi: 10.1371/journal.pone.0292176. PMID: 37782633; PMCID: PMC10545116.

October 2, Pubcrawler Hits:

1. Šeflová J, Schwarz JA, Smith AN, Svensson B, Blackwell DJ, Phillips TA, Nikolaienko R, Bovo E, Rebbeck RT, Zima AV, Thomas DD, Van Petegem F, Knollmann BC, Johnston JN, Robia SL, Cornea RL. RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET. ACS Chem Biol. 2023 Sep 28. doi: 10.1021/acschembio.3c00376. Epub ahead of print. PMID: 37769131.

2. McLean MA, Nakajima L, Chau CMY, Weinberg J, Synnes AR, Miller SP, Grunau RE. Cortisol levels are related to neonatal pain exposure in children born very preterm at age 18 months in two independent cohorts. Paediatr Neonatal Pain. 2023 May 29;5(3):86-95. doi: 10.1002/pne2.12112. PMID: 37744280; PMCID: PMC10514780.

3. McCallum G, Tropini C. The gut microbiota and its biogeography. Nat Rev Microbiol. 2023 Sep 22. doi: 10.1038/s41579-023-00969-0. Epub ahead of print. PMID: 37740073.

4. Jelen M, Musso PY, Junca P, Gordon MD. Optogenetic induction of appetitive and aversive taste memories in Drosophila. Elife. 2023 Sep 26;12:e81535. doi: 10.7554/eLife.81535. Epub ahead of print. PMID: 37750673.

5. Barbash DA, Jin B, Wei KH, Dion-Côté AM. Testing a candidate meiotic drive locus identified by pool sequencing. G3 (Bethesda). 2023 Sep 28:jkad225. doi: 10.1093/g3journal/jkad225. Epub ahead of print. PMID: 37766472.

September 25, Pubcrawler Hits:

1. Scriven DRL, Johnsen AB, Asghari P, Chou KC, Moore EDW. Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol. J Gen Physiol. 2023 Nov 6;155(11):e202213109. doi: 10.1085/jgp.202213109. Epub 2023 Sep 20. PMID: 37728575; PMCID: PMC10513110.

September 18, Pubcrawler Hits:

1. Chan M, Sahakyan H, Eldstrom J, Sastre D, Wang Y, Dou Y, Pourrier M, Vardanyan V, Fedida D. A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes. Elife. 2023 Sep 14;12:RP87038. doi: 10.7554/eLife.87038. PMID: 37707495; PMCID: PMC10501768.

2. Worrall LJ, Majewski DD, Strynadka NCJ. Structural Insights into Type III Secretion Systems of the Bacterial Flagellum and Injectisome. Annu Rev Microbiol. 2023 Sep 15;77:669-698. doi: 10.1146/annurev-micro-032521-025503. PMID: 37713458.

3. Zhao Z, Khurana A, Antony F, Young JW, Hewton KG, Brough Z, Zhong T, Parker SJ, Duong van Hoa F. A Peptidisc-Based Survey of the Plasma Membrane Proteome of a Mammalian Cell. Mol Cell Proteomics. 2023 Aug;22(8):100588. doi: 10.1016/j.mcpro.2023.100588. Epub 2023 Jun 7. PMID: 37295717; PMCID: PMC10416069.

September 11, Pubcrawler Hits:

1. Kieft B, Finke N, McLaughlin RJ, Nallan AN, Krzywinski M, Crowe SA, Hallam SJ. Genome-resolved correlation mapping links microbial community structure to metabolic interactions driving methane production from wastewater. Nat Commun. 2023 Sep 4;14(1):5380. doi: 10.1038/s41467-023-40907-5. PMID: 37666802; PMCID: PMC10477309.

2. Ramzy A, Saber N, Bruin JE, Thompson DM, Kim PT, Warnock GL, Kieffer TJ. Thyroid hormone levels correlate with the maturation of implanted pancreatic endoderm cells in patients with type 1 diabetes. J Clin Endocrinol Metab. 2023 Sep 6:dgad499. doi: 10.1210/clinem/dgad499. Epub ahead of print. PMID: 37671625.

3. Mogensen LS, Mikkelsen SA, Tadini-Buoninsegni F, Holm R, Matsell E, Vilsen B, Molday RS, Andersen JP. On the track of the lipid transport pathway of the phospholipid flippase ATP8A2 - Mutation analysis of residues of the transmembrane segments M1, M2, M3 and M4. Biochim Biophys Acta Mol Cell Res. 2023 Sep 5:119570. doi: 10.1016/j.bbamcr.2023.119570. Epub ahead of print. PMID: 37678495.

4. van Dijk MJ, van Oirschot BA, Harrison AN, Recktenwald SM, Qiao M, Stommen A, Cloos AS, Vanderroost J, Terrasi R, Dey K, Bos J, Rab MAE, Bogdanova A, Minetti G, Muccioli GG, Tyteca D, Egée S, Kaestner L, Molday RS, van Beers EJ, van Wijk R. A novel missense variant in ATP11C is associated with reduced red blood cell phosphatidylserine flippase activity and mild hereditary hemolytic anemia. Am J Hematol. 2023 Sep 6. doi: 10.1002/ajh.27088. Epub ahead of print. PMID: 37671681.

5. Maxwell JR, DiDomenico J, Roberts MH, Marquez LE, Rai R, Weinberg J, Jacobson SW, Stephen J, Bakhireva LN. Impact of low-level prenatal alcohol exposure and maternal stress on autonomic regulation. Pediatr Res. 2023 Sep 6. doi: 10.1038/s41390-023-02799-5. Epub ahead of print. PMID: 37674025.

6. Xie X, Yu T, Li X, Zhang N, Foster LJ, Peng C, Huang W, He G. Recent advances in targeting the "undruggable" proteins: from drug discovery to clinical trials. Signal Transduct Target Ther. 2023 Sep 6;8(1):335. doi: 10.1038/s41392-023-01589-z. PMID: 37669923; PMCID: PMC10480221.

7. Horvath RM, Brumme ZL, Sadowski I. CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells. J Virol. 2023 Sep 6:e0092323. doi: 10.1128/jvi.00923-23. Epub ahead of print. PMID: 37671866.

September 4, Pubcrawler Hits:

1. Li S, Sharaf MG, Rowe EM, Serrano K, Devine DV, Unsworth LD. Hemocompatibility of β-Cyclodextrin-Modified (Methacryloyloxy)ethyl Phosphorylcholine Coated Magnetic Nanoparticles. Biomolecules. 2023 Jul 25;13(8):1165. doi: 10.3390/biom13081165. PMID: 37627230; PMCID: PMC10452919.

August 28, Pubcrawler Hits:

1. Castillo-Castrejon M, Sankofi BM, Murguia SJ, Udeme AA, Cen HH, Xia YH, Thomas NS, Berry WL, Jones KL, Richard VR, Zahedi RP, Borchers CH, Johnson JD, Wellberg EA. FGF1 supports glycolytic metabolism through the estrogen receptor in endocrine-resistant and obesity-associated breast cancer. Breast Cancer Res. 2023 Aug 22;25(1):99. doi: 10.1186/s13058-023-01699-0. PMID: 37608351.

2. Tixi W, Maldonado M, Chang YT, Chiu A, Yeung W, Parveen N, Nelson MS, Hart R, Wang S, Hsu WJ, Fueger P, Kopp JL, Huising MO, Dhawan S, Shih HP. Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation. Elife. 2023 Aug 23;12:e90006. doi: 10.7554/eLife.90006. Epub ahead of print. PMID: 37610090.

3. Onodera Y, Liang J, Li Y, Griffin B, Thanabalasingam T, Lu C, Zhu J, Liu M, Moraes T, Zheng W, Khateeb J, Khang J, Huang Y, Jerkic M, Nakane M, Baker A, Orser B, Chen YW, Wirnsberger G, Penninger JM, Rotstein OD, Slutsky AS, Li Y, Mubareka S, Zhang H. Inhalation of ACE2 as a therapeutic target on sex-bias differences in SARS-CoV-2 infection and variant of concern. iScience. 2023 Jul 25;26(8):107470. doi: 10.1016/j.isci.2023.107470. PMID: 37609639; PMCID: PMC10440513.

August 21, Pubcrawler Hits:

1. Kaltak M, Blanco-Garavito R, Molday LL, Dhaenens CM, Souied EE, Platenburg G, Swildens J, Molday RS, Cremers FPM. Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function. J Transl Med. 2023 Aug 16;21(1):546. doi: 10.1186/s12967-023-04406-x. PMID: 37587475; PMCID: PMC10428568.

2. Flanagan K, Pelech S, Av-Gay Y, Dao Duc K. CAT PETR: a graphical user interface for differential analysis of phosphorylation and expression data. Stat Appl Genet Mol Biol. 2023 Aug 21;22(1). doi: 10.1515/sagmb-2023-0017. PMID: 37592851.

3. Xu T, Ji H, Xu L, Cheng S, Liu X, Li Y, Zhong R, Zhao W, Kizhakkedathu JN, Zhao C. Self-anticoagulant sponge for whole blood auto-transfusion and its mechanism of coagulation factor inactivation. Nat Commun. 2023 Aug 12;14(1):4875. doi: 10.1038/s41467-023-40646-7. PMID: 37573353; PMCID: PMC10423252.

August 14, Pubcrawler Hits:

1. Chander N, Basha G, Yan Cheng MH, Witzigmann D, Cullis PR. Lipid nanoparticle mRNA systems containing high levels of sphingomyelin engender higher protein expression in hepatic and extra-hepatic tissues. Mol Ther Methods Clin Dev. 2023 Jun 12;30:235-245. doi: 10.1016/j.omtm.2023.06.005. PMID: 37564393; PMCID: PMC10410000.

2. Andrews DDT, Vlok M, Akbari Bani D, Hay BN, Mohamud Y, Foster LJ, Luo H, Overall CM, Jan E. Cleavage of 14-3-3ε by the enteroviral 3C protease dampens RIG-I-mediated antiviral signaling. J Virol. 2023 Aug 9:e0060423. doi: 10.1128/jvi.00604-23. Epub ahead of print. PMID: 37555661.

3. Pérez-Vargas J, Worrall LJ, Olmstead AD, Ton AT, Lee J, Villanueva I, Thompson CAH, Dudek S, Ennis S, Smith JR, Shapira T, Guzman J, Gang S, Ban F, Vuckovic M, Bielecki M, Kovacic S, Kenward C, Hong CY, Gordon DG, Levett PN, Krajden M, Leduc R, Boudreault PL, Niikura M, Paetzel M, Young RN, Cherkasov A, Strynadka NCJ, Jean F. A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect. 2023 Aug 9:2246594. doi: 10.1080/22221751.2023.2246594. Epub ahead of print. PMID: 37555275.

August 7, Pubcrawler Hits:

1. Ellis CE, Mojibian M, Ida S, Fung VCW, Skovsø S, McIver E, O'Dwyer S, Webber TD, Braam MJS, Saber N, Sasaki S, Lynn FC, Kieffer TJ, Levings MK. Human A2-CAR T Cells Reject HLA-A2+ Human Islets Transplanted Into Mice Without Inducing Graft-Versus-Host Disease. Transplantation. 2023 Aug 2. doi: 10.1097/TP.0000000000004709. Epub ahead of print. PMID: 37528526.

2. Golla K, Paul M, Lengyell TC, Simpson EM, Falet H, Kim H. A novel association between platelet filamin A and soluble N-ethylmaleimide sensitive factor attachment proteins regulates granule secretion. Res Pract Thromb Haemost. 2022 Dec 20;7(4):100019. doi: 10.1016/j.rpth.2022.100019. PMID: 37538498; PMCID: PMC10394388.

3. Bodnar TS, Chao A, Holman PJ, Ellis L, Raineki C, Weinberg J. Impact of the COVID-19 pandemic on adults with Fetal Alcohol Spectrum Disorder: linking immune function to mental health status. Front Neurosci. 2023 Jul 19;17:1214100. doi: 10.3389/fnins.2023.1214100. PMID: 37539379; PMCID: PMC10394466.

4. Miller T, Lange D, Kizhakkedathu JN, Yu K, Felix D, Samejima S, Shackleton C, Malik RN, Sachdeva R, Walter M, Krassioukov AV. The Microbiological Burden of Short-Term Catheter Reuse in Individuals with Spinal Cord Injury: A Prospective Study. Biomedicines. 2023 Jul 7;11(7):1929. doi: 10.3390/biomedicines11071929. PMID: 37509568; PMCID: PMC10377649.

5. Horvath RM, Sadowski I. Upstream Stimulatory Factors Regulate HIV-1 Latency and Are Required for Robust T Cell Activation. Viruses. 2023 Jun 28;15(7):1470. doi: 10.3390/v15071470. PMID: 37515158; PMCID: PMC10384547.

July 31, Pubcrawler Hits:

1. Littlejohn PT, Bar-Yoseph H, Edwards K, Li H, Ramirez-Contreras CY, Holani R, Metcalfe-Roach A, Fan YM, Yang TM, Radisavljevic N, Hu X, Johnson JD, Finlay BB. Multiple micronutrient deficiencies alter energy metabolism in host and gut microbiome in an early-life murine model. Front Nutr. 2023 Jul 10;10:1151670. doi: 10.3389/fnut.2023.1151670. PMID: 37497061; PMCID: PMC10365968.

2. Yu H, Worrall LJ, Berger T, Petric M, Lin BH, Vuckovic M, Robb CS, Le Q, Kenward C, Dai C, Wakeham A, Liu S, Snow B, Tobin C, Budylowski P, Guvenc F, You-Ten A, Haight J, Silvester J, Singh RP, Ahn SK, Sultana A, Poon B, Lam J, Christie-Holmes N, Ostrowski M, Gray-Owen SD, Kubli S, Mak T, Strynadka NCJ, Brunham RC. Identification of an optimized Receptor-Binding Domain Subunit Vaccine against SARS-CoV-2. J Immunol. 2023 Jul 26:ji2300282. doi: 10.4049/jimmunol.2300282. Epub ahead of print. PMID: 37493438.

July 24, Pubcrawler Hits:

1. Berger M, Easterbrook A, Holloway K, Devine D, Bansback N. What influences decisions to donate plasma? A rapid review of the literature. Vox Sang. 2023 Jul 20. doi: 10.1111/vox.13496. Epub ahead of print. PMID: 37470275.

2. Xie X, Zhang N, Li X, Huang H, Peng C, Huang W, Foster LJ, He G, Han B. Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy. Bioorg Chem. 2023 Jul 8;139:106721. doi: 10.1016/j.bioorg.2023.106721. Epub ahead of print. PMID: 37467620.

3. Forgrave LM, Moon KM, Hamden JE, Li Y, Lu P, Foster LJ, Mackenzie IRA, DeMarco ML. Truncated TDP-43 proteoforms diagnostic of frontotemporal dementia with TDP-43 pathology. Alzheimers Dement. 2023 Jul 17. doi: 10.1002/alz.13368. Epub ahead of print. PMID: 37461300.

4. Fenstermaker TK, Petruk S, Kovermann SK, Brock HW, Mazo A. RNA polymerase II associates with active genes during DNA replication. Nature. 2023 Jul 19. doi: 10.1038/s41586-023-06341-9. Epub ahead of print. PMID: 37468626.

July 17, Pubcrawler Hits:

1. Abaeva IS, Young C, Warsaba R, Khan N, Tran LV, Jan E, Pestova TV, Hellen CUT. The structure and mechanism of action of a distinct class of dicistrovirus intergenic region IRESs. Nucleic Acids Res. 2023 Jul 10:gkad569. doi: 10.1093/nar/gkad569. Epub ahead of print. PMID: 37427788.

2. Zhao J, Liang S, Braam MJS, Baker RK, Iworima DG, Quiskamp N, Kieffer TJ. Differentiation of Human Pluripotent Stem Cells into Insulin-Producing Islet Clusters. J Vis Exp. 2023 Jun 23;(196). doi: 10.3791/64840. PMID: 37427943.

3. Alhasan MM, Hölsken O, Duerr C, Helfrich S, Branzk N, Philipp A, Leitz D, Duerr J, Almousa Y, Barrientos G, Mohn WW, Gamradt S, Conrad ML. Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut-lung axis. Eur J Immunol. 2023 Jul 10:e2350394. doi: 10.1002/eji.202350394. Epub ahead of print. PMID: 37431194.

4. Ng KM, Pannu S, Liu S, Burckhardt JC, Hughes T, Van Treuren W, Nguyen J, Naqvi K, Nguyen B, Clayton CA, Pepin DM, Collins SR, Tropini C. Single-strain behavior predicts responses to environmental pH and osmolality in the gut microbiota. mBio. 2023 Jul 11:e0075323. doi: 10.1128/mbio.00753-23. Epub ahead of print. PMID: 37432034.

5. Akinlaja MO, Stacey RG, Chan QWT, Foster LJ. Discovering Protein-Protein Interactions using Co-Fractionation-Mass Spectrometry with Label-Free Quantitation. Methods Mol Biol. 2023;2690:241-253. doi: 10.1007/978-1-0716-3327-4_21. PMID: 37450152.

July 10, Pubcrawler Hits:

1. Clayworth K, Gilbert M, Auld V. Dissection and Immunolabeling of the Central and Peripheral Nervous System of Drosophila Larvae. Cold Spring Harb Protoc. 2023 Jun 30. doi: 10.1101/pdb.prot108160. Epub ahead of print. PMID: 37399181.

2. Clayworth K, Gilbert M, Auld V. Proximity Ligation Assay (PLA) for Fillets of Drosophila Larvae. Cold Spring Harb Protoc. 2023 Jun 30. doi: 10.1101/pdb.prot108162. Epub ahead of print. PMID: 37399180.

3. Clayworth K, Gilbert M, Auld V. Cell Biology Techniques for Studying Drosophila Peripheral Glial Cells. Cold Spring Harb Protoc. 2023 Jun 30. doi: 10.1101/pdb.top108159. Epub ahead of print. PMID: 37399179.

4. Clayworth K, Gilbert M, Auld V. Whole-Larva Cryosectioning and Immunolabeling of Drosophila Larvae. Cold Spring Harb Protoc. 2023 Jun 30. doi: 10.1101/pdb.prot108161. Epub ahead of print. PMID: 37399178.

5. McGregor AK, Chan ACK, Schroeder MD, Do LTM, Saini G, Murphy MEP, Wolthers KR. A new member of the flavodoxin superfamily from Fusobacterium nucleatum that functions in heme trafficking and reduction of anaerobilin. J Biol Chem. 2023 Jun 10;299(7):104902. doi: 10.1016/j.jbc.2023.104902. Epub ahead of print. PMID: 37302554.

6. Harris NJ, Jenkins ML, Nam SE, Rathinaswamy MK, Parson MAH, Ranga-Prasad H, Dalwadi U, Moeller BE, Sheeky E, Hansen SD, Yip CK, Burke JE. Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain. Elife. 2023 Jul 7;12:RP88058. doi: 10.7554/eLife.88058. PMID: 37417733.

7. Pike VL, Stevens EJ, Griffin AS, King KC. Within- and between-host dynamics of producer and non-producer pathogens. Parasitology. 2023 Jul 3:1-33. doi: 10.1017/S0031182023000586. Epub ahead of print. PMID: 37394480.

July 3, Pubcrawler Hits:

1. Blagojevic P, Perez-Vargas J, Jian K, Williams DE, Villanueva I, Thompson CAH, Ennis S, Niikura M, Tietjen I, Jean F, Andersen RJ. Synthetic Analogs of the Sponge Sesterterpenoid Alotaketal C are Potent Inhibitors of SARS-CoV-2 Omicron BA.1 and BA.5 Infections of Human Lung Cells. Org Lett. 2023 Jun 26. doi: 10.1021/acs.orglett.3c01536. Epub ahead of print. PMID: 37358030.

2. Cardoen B, Ben Yedder H, Lee S, Nabi IR, Hamarneh G. DataCurator.jl: efficient, portable and reproducible validation, curation and transformation of large heterogeneous datasets using human-readable recipes compiled into machine-verifiable templates. Bioinform Adv. 2023 Jun 1;3(1):vbad068. doi: 10.1093/bioadv/vbad068. PMID: 37359728; PMCID: PMC10290225.

3. Guskjolen A, Cembrowski MS. Engram neurons: Encoding, consolidation, retrieval, and forgetting of memory. Mol Psychiatry. 2023 Jun 28. doi: 10.1038/s41380-023-02137-5. Epub ahead of print. PMID: 37369721.

4. Ji H, Li Y, Su B, Zhao W, Kizhakkedathu JN, Zhao C. Advances in Enhancing Hemocompatibility of Hemodialysis Hollow-Fiber Membranes. Adv Fiber Mater. 2023 Apr 3:1-43. doi: 10.1007/s42765-023-00277-5. Epub ahead of print. PMID: 37361105; PMCID: PMC10068248.

5. Yavarinasab A, Flibotte A, Liu A, Tropini C. An impedance-based chemiresistor for the real-time, simultaneous detection of gut microbiota-generated short-chain fatty acids. Sensors and Actuators B: Chemical. 2023. doi: 10.1016/j.snb.2023.134182. Share Link:

June 26, Pubcrawler Hits:

1. Grigg JC, Copp JN, Krekhno JMC, Liu J, Ibrahimova A, Eltis LD. Deciphering the biosynthesis of a novel lipid in Mycobacterium tuberculosis expands the known roles of the nitroreductase superfamily. J Biol Chem. 2023 Jun 14:104924. doi: 10.1016/j.jbc.2023.104924. Epub ahead of print. PMID: 37328106.

June 19, Pubcrawler Hits:

1. Kang L, Yang AL, Lai CH, Chen TJ, Lin SY, Wang YH, Wang CZ, Conway EM, Wu HL, Ho ML, Chang JK, Chen CH, Cheng TL. Chondrocyte Thrombomodulin Protects against Osteoarthritis. Int J Mol Sci. 2023 May 30;24(11):9522. doi: 10.3390/ijms24119522. PMID: 37298473; PMCID: PMC10253941.

2. Vega AA, Marshall EA, Noonan AJC, Filho FSL, Yang J, Stewart GL, Johnson FD, Vucic EA, Pewarchuk ME, Shah PP, Clem BF, Nislow C, Lam S, Lockwood WW, Hallam SJ, Leung JM, Beverly LJ, Lam WL. Methionine-producing tumor micro(be) environment fuels growth of solid tumors. Cell Oncol (Dordr). 2023 Jun 15. doi: 10.1007/s13402-023-00832-7. Epub ahead of print. PMID: 37318751.

3. Liang S, Zhao J, Baker RK, Tran E, Zhan L, Kieffer TJ. Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system. Cell Rep Methods. 2023 May 5;3(5):100466. doi: 10.1016/j.crmeth.2023.100466. PMID: 37323565; PMCID: PMC10261893.

June 12, Pubcrawler Hits:

1. Stokes T, Cen HH, Kapranov P, Gallagher IJ, Pitsillides AA, Volmar CH, Kraus WE, Johnson JD, Phillips SM, Wahlestedt C, Timmons JA. Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq. Adv Genet (Hoboken). 2023 Jan 17;4(2):2200024. doi: 10.1002/ggn2.202200024. PMID: 37288167; PMCID: PMC10242409.

2. Bharathan NK, Giang W, Hoffman CL, Aaron JS, Khuon S, Chew TL, Preibisch S, Trautman ET, Heinrich L, Bogovic J, Bennett D, Ackerman D, Park W, Petruncio A, Weigel AV, Saalfeld S; COSEM Project Team; Wayne Vogl A, Stahley SN, Kowalczyk AP. Architecture and dynamics of a desmosome-endoplasmic reticulum complex. Nat Cell Biol. 2023 Jun 8. doi: 10.1038/s41556-023-01154-4. Epub ahead of print. PMID: 37291267.

June 5, Pubcrawler Hits:

1. Alim NTB, Koppenhöfer S, Lang AS, Beatty JT. Extracellular Polysaccharide Receptor and Receptor-Binding Proteins of the Rhodobacter capsulatus Bacteriophage-like Gene Transfer Agent RcGTA. Genes (Basel). 2023 May 22;14(5):1124. doi: 10.3390/genes14051124. PMID: 37239483; PMCID: PMC10218006.

2. Peeters S, Leung T, Fornes O, Farkas RA, Wasserman WW, Brown CJ. Refining the genomic determinants underlying escape from X-chromosome inactivation. NAR Genom Bioinform. 2023 May 30;5(2):lqad052. doi: 10.1093/nargab/lqad052. PMID: 37260510; PMCID: PMC10227363.

3. Anstett J, Plominsky AM, DeLong EF, Kiesser A, Jürgens K, Morgan-Lang C, Stepanauskas R, Stewart FJ, Ulloa O, Woyke T, Malmstrom R, Hallam SJ. A compendium of bacterial and archaeal single-cell amplified genomes from oxygen deficient marine waters. Sci Data. 2023 May 27;10(1):332. doi: 10.1038/s41597-023-02222-y. PMID: 37244914; PMCID: PMC10224968.

4. Braam MJS, Zhao J, Liang S, Ida S, Kloostra NK, Iworima DG, Tang M, Baker RK, Quiskamp N, Piret JM, Kieffer TJ. Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension culture. Sci Rep. 2023 Jun 1;13(1):8877. doi: 10.1038/s41598-023-35716-1. PMID: 37264038; PMCID: PMC10235054.

5. Wang S, Dong X, Maazi M, Chen N, Mahil A, Kopp JL. GABA treatment does not induce neogenesis of new endocrine cells from pancreatic ductal cells. Islets. 2023 Dec 31;15(1):2219477. doi: 10.1080/19382014.2023.2219477. PMID: 37258189; PMCID: PMC10234131.

6. Bell PA, Overall CM. No Substrate Left behind-Mining of Shotgun Proteomics Datasets Rescues Evidence of Proteolysis by SARS-CoV-2 3CLpro Main Protease. Int J Mol Sci. 2023 May 13;24(10):8723. doi: 10.3390/ijms24108723. PMID: 37240067; PMCID: PMC10218362.

May 29, Pubcrawler Hits:

1. Vesnaver E, Gibson E, Goldman M, Butler-Foster T, Hill NE, Lapierre D, MacDonagh R, Rubini KA, Miguel G, Rosser A, MacPherson P, Palumbo A, Randall T, Osbourne-Sorrell W, O'Brien SF, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J. Navigating imperfect policies to donate plasma: Survey on plasma donation and a pilot plasma donation program among men who have sex with men in Canada. Transfusion. 2023 May 23. doi: 10.1111/trf.17398. Epub ahead of print. PMID: 37218408.

2. Haji-Ghassemi O, Chen YS, Woll K, Gurrola GB, Valdivia CR, Cai W, Li S, Valdivia HH, Van Petegem F. Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation. Sci Adv. 2023 May 24;9(21):eadf4936. doi: 10.1126/sciadv.adf4936. Epub 2023 May 24. PMID: 37224245; PMCID: PMC10208580.

3. Malwal SR, Mazurek B, Ko J, Xie P, Barnes C, Varvitsiotis C, Zimmerman MD, Olatunji S, Lee J, Xie M, Sarathy J, Caffrey M, Strynadka NCJ, Dartois V, Dick T, Lee BNR, Russell DG, Oldfield E. Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria. J Med Chem. 2023 May 26. doi: 10.1021/acs.jmedchem.3c00398. Epub ahead of print. PMID: 37235809.

4. Malik B, Vokic I, Mohr T, Poppelaars M, Holcmann M, Novoszel P, Timelthaler G, Lendl T, Krauss D, Elling U, Mildner M, Penninger JM, Petzelbauer P, Sibilia M, Csiszar A. FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice. EMBO Mol Med. 2023 May 25:e16758. doi: 10.15252/emmm.202216758. Epub ahead of print. PMID: 37226685.

5. Nagra A, Katsube M, Gao W, Rosin JM, Vora SR. Embryonic inhibition of colony-stimulating factor 1 receptor impacts craniofacial morphogenesis. Orthod Craniofac Res. 2023 May 25. doi: 10.1111/ocr.12671. Epub ahead of print. PMID: 37231583.

May 22, Pubcrawler Hits:

1. Cheng MHY, Leung J, Zhang Y, Strong C, Basha G, Momeni A, Chen Y, Jan E, Abdolahzadeh A, Wang X, Kulkarni JA, Witzigmann D, Cullis PR. Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency. Adv Mater. 2023 May 12:e2303370. doi: 10.1002/adma.202303370. Epub ahead of print. PMID: 37172950.

2. Cholak S, Saville JW, Zhu X, Berezuk AM, Tuttle KS, Haji-Ghassemi O, Alvarado FJ, Van Petegem F, Subramaniam S. Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure. 2023 May 3:S0969-2126(23)00132-6. doi: 10.1016/j.str.2023.04.009. Epub ahead of print. PMID: 37192614.

3. Parmar S, Tocheva EI. The cell envelope of Mycobacterium abscessus and its role in pathogenesis. PLoS Pathog. 2023 May 18;19(5):e1011318. doi: 10.1371/journal.ppat.1011318. PMID: 37200238; PMCID: PMC10194924.

4. Vappala S, Smith SA, Kizhakkedathu JN, Morrissey JH. Inhibitors of Polyphosphate and Neutrophil Extracellular Traps. Semin Thromb Hemost. 2023 May 16. doi: 10.1055/s-0043-1768936. Epub ahead of print. PMID: 37192652.

5. Plemel JR, Rosin JM, Tremblay MÈ. Editorial: Insights in non-neuronal cells: 2021. Front Cell Neurosci. 2023 Apr 26;17:1199518. doi: 10.3389/fncel.2023.1199518. PMID: 37180946; PMCID: PMC10169738.

6. Bacheva V, Firouzeh A, Leroy E, Balciunaite A, Davila D, Gabay I, Paratore F, Bercovici M, Shea H, Kaigala G. Dynamic control of high-voltage actuator arrays by light-pattern projection on photoconductive switches. Microsyst Nanoeng. 2023 May 16;9:59. doi: 10.1038/s41378-023-00528-w. PMID: 37201103; PMCID: PMC10185468.

May 8, Pubcrawler Hits:

1. Frirdich E, Vermeulen J, Biboy J, Vollmer W, Gaynor EC. Multiple Campylobacter jejuni proteins affecting the peptidoglycan structure and the degree of helical cell curvature. Front Microbiol. 2023 Apr 18;14:1162806. doi: 10.3389/fmicb.2023.1162806. PMID: 37143542; PMCID: PMC10151779.

2. Ulziikhuu B, Gombojav E, Banzrai C, Batsukh S, Enkhtuya E, Boldbaatar B, Bellinger DC, Lanphear B, McCandless L, Nepomnaschy P, Salvante K, Weinberg J, Allen RW. Who benefits most from a prenatal HEPA filter air cleaner intervention on childhood cognitive development? The UGAAR randomized controlled trial. Environ Res. 2023 Apr 28:115991. doi: 10.1016/j.envres.2023.115991. Epub ahead of print. PMID: 37121346.

3. Hay BN, Akinlaja MO, Baker TC, Houfani AA, Stacey RG, Foster LJ. Integration of data-independent acquisition (DIA) with co-fractionation mass spectrometry (CF-MS) to enhance interactome mapping capabilities. Proteomics. 2023 May 5:e2200278. doi: 10.1002/pmic.202200278. Epub ahead of print. PMID: 37144656.

4. Pan Z, Zhao Y, Wang X, Xie X, Liu M, Zhang K, Wang L, Bai D, Foster LJ, Shu R, He G. Targeting bromodomain-containing proteins: research advances of drug discovery. Mol Biomed. 2023 May 5;4(1):13. doi: 10.1186/s43556-023-00127-1. PMID: 37142850; PMCID: PMC10159834.

5. Young JW, Zhao Z, Wason IS, Duong van Hoa F. A Dual Detergent Strategy to Capture a Bacterial Outer Membrane Proteome in Peptidiscs for Characterization by Mass Spectrometry and Binding Assays. J Proteome Res. 2023 May 5;22(5):1537-1545. doi: 10.1021/acs.jproteome.2c00560. Epub 2022 Dec 14. PMID: 36516475.

May 1, Pubcrawler Hits:

1. La CC, Smith SA, Vappala S, Adili R, Luke CE, Abbina S, Luo HD, Chafeeva I, Drayton M, Creagh LA, de Guadalupe Jaraquemada-Peláez M, Rhoads N, Kalathottukaren MT, Henke PK, Straus SK, Du C, Conway EM, Holinstat M, Haynes CA, Morrissey JH, Kizhakkedathu JN. Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design. Nat Commun. 2023 Apr 26;14(1):2177. doi: 10.1038/s41467-023-37709-0. PMID: 37100783; PMCID: PMC10133246.

2. Vesnaver E, Butler-Foster T, Goldman M, Gibson E, Palumbo A, Lapierre D, Hill NE, MacDonagh R, Rubini KA, Bridel W, Miguel G, Rosser A, MacPherson P, Randall T, Osbourne-Sorrell W, O'Brien SF, Otis J, Greaves M, Al-Bakri TB, Germain M, Orvis S, Clapperton AT, Reid M, Labrecque M, Devine D, Presseau J. Improved access yet inequitable experience: gay, bisexual and other men who have sex with men's views of more inclusive criteria for source plasma donation. BMC Public Health. 2023 Apr 25;23(1):768. doi: 10.1186/s12889-023-15424-1. PMID: 37098497; PMCID: PMC10131411.

3. Price RM, Budzyński MA, Shen J, Mitchell JE, Kwan JZJ, Teves SS. Heat shock transcription factors demonstrate a distinct mode of interaction with mitotic chromosomes. Nucleic Acids Res. 2023 Apr 28:gkad304. doi: 10.1093/nar/gkad304. Epub ahead of print. PMID: 37114996.

4. Sexton DL, Hashimi A, Beskrovnaya P, Sibanda L, Huan T, Tocheva EI. The cell envelope of Thermotogae suggests a mechanism for outer membrane biogenesis. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2303275120. doi: 10.1073/pnas.2303275120. Epub 2023 Apr 24. PMID: 37094164.

5. Cotton S, Clayton CA, Tropini C. Microbial endocrinology: the mechanisms by which the microbiota influences host sex steroids. Trends Microbiol. 2023 Apr 24:S0966-842X(23)00090-2. doi: 10.1016/j.tim.2023.03.010. Epub ahead of print. PMID: 37100633.

6. Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, Häcker G, Hajnóczky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, Jäättelä M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T, Kelly GL, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Kluck R, Krysko DV, Kulms D, Kumar S, Lavandero S, Lavrik IN, Lemasters JJ, Liccardi G, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Luedde T, MacFarlane M, Madeo F, Malorni W, Manic G, Mantovani R, Marchi S, Marine JC, Martin SJ, Martinou JC, Mastroberardino PG, Medema JP, Mehlen P, Meier P, Melino G, Melino S, Miao EA, Moll UM, Muñoz-Pinedo C, Murphy DJ, Niklison-Chirou MV, Novelli F, Núñez G, Oberst A, Ofengeim D, Opferman JT, Oren M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pentimalli F, Pereira DM, Pervaiz S, Peter ME, Pinton P, Porta G, Prehn JHM, Puthalakath H, Rabinovich GA, Rajalingam K, Ravichandran KS, Rehm M, Ricci JE, Rizzuto R, Robinson N, Rodrigues CMP, Rotblat B, Rothlin CV, Rubinsztein DC, Rudel T, Rufini A, Ryan KM, Sarosiek KA, Sawa A, Sayan E, Schroder K, Scorrano L, Sesti F, Shao F, Shi Y, Sica GS, Silke J, Simon HU, Sistigu A, Stephanou A, Stockwell BR, Strapazzon F, Strasser A, Sun L, Sun E, Sun Q, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Troy CM, Turk B, Urbano N, Vandenabeele P, Vanden Berghe T, Vander Heiden MG, Vanderluit JL, Verkhratsky A, Villunger A, von Karstedt S, Voss AK, Vousden KH, Vucic D, Vuri D, Wagner EF, Walczak H, Wallach D, Wang R, Wang Y, Weber A, Wood W, Yamazaki T, Yang HT, Zakeri Z, Zawacka-Pankau JE, Zhang L, Zhang H, Zhivotovsky B, Zhou W, Piacentini M, Kroemer G, Galluzzi L. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death Differ. 2023 Apr 26:1–58. doi: 10.1038/s41418-023-01153-w. Epub ahead of print. PMID: 37100955; PMCID: PMC10130819.

7. Bolori S, Shegefti S, Baghaei K, Yadegar A, Moon KM, Foster LJ, Nasiri MJ, Dabiri H. The Effects of Helicobacter pylori-Derived Outer Membrane Vesicles on Hepatic Stellate Cell Activation and Liver Fibrosis In Vitro. Biomed Res Int. 2023 Apr 12;2023:4848643. doi: 10.1155/2023/4848643. PMID: 37090196; PMCID: PMC10116224.

8. Herout R, Vappala S, Hanstock S, Moskalev I, Chew BH, Kizhakkedathu JN, Lange D. Development of a High-Throughput Urosepsis Mouse Model. Pathogens. 2023 Apr 15;12(4):604. doi: 10.3390/pathogens12040604. PMID: 37111490; PMCID: PMC10143079.

April 24, Pubcrawler Hits:

1. Mastracci TL, Apte M, Amundadottir LT, Alvarsson A, Artandi S, Bellin MD, Bernal-Mizrachi E, Caicedo A, Campbell-Thompson M, Cruz-Monserrate Z, El Ouaamari A, Gaulton KJ, Geisz A, Goodarzi MO, Hara M, Hull-Meichle RL, Kleger A, Klein AP, Kopp JL, Kulkarni RN, Muzumdar MD, Naren AP, Oakes SA, Olesen SS, Phelps EA, Powers AC, Stabler CL, Tirkes T, Whitcomb DC, Yadav D, Yong J, Zaghloul NA, Sander M, Pandol SJ. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Pancreas. 2022 Oct 1;51(9):1061-1073. doi: 10.1097/MPA.0000000000002170. PMID: 37078927.

2. Voskoboinyk D, Mahmoodi N, Lin CS, Murphy MEP, Tanner ME. Aldehyde-Based Inhibitors of the Peptidoglycan O-Acetylesterase Ape. Chembiochem. 2023 Apr 17:e202300205. doi: 10.1002/cbic.202300205. Epub ahead of print. PMID: 37069132.

3. McMahan RH, Anton P, Coleman LG Jr, Cresci GAM, Crews FT, Crotty KM, Luck ME, Molina PE, Vachharajani V, Weinberg J, Yeligar SM, Choudhry MA, McCullough RL, Kovacs EJ. Alcohol and Immunology: Mechanisms of Multi-Organ Damage. Summary of the 2022 Alcohol and Immunology Research Interest Group (AIRIG) meeting. Alcohol. 2023 Apr 13:S0741-8329(23)00203-3. doi: 10.1016/j.alcohol.2023.04.002. Epub ahead of print. PMID: 37061143.

4. Golmohammadzadeh M, Sexton DL, Parmar S, Tocheva EI. Advanced imaging techniques: microscopy. Adv Appl Microbiol. 2023;122:1-25. doi: 10.1016/bs.aambs.2023.01.001. Epub 2023 Feb 27. PMID: 37085191.

5. Devignot S, Sha TW, Burkard TR, Schmerer P, Hagelkruys A, Mirazimi A, Elling U, Penninger JM, Weber F. Low-density lipoprotein receptor-related protein 1 (LRP1) as an auxiliary host factor for RNA viruses. Life Sci Alliance. 2023 Apr 18;6(7):e202302005. doi: 10.26508/lsa.202302005. PMID: 37072184; PMCID: PMC10114362.

6. Plante S, Moon KM, Lemieux P, Foster LJ, Landry CR. Breaking spore dormancy in budding yeast transforms the cytoplasm and the solubility of the proteome. PLoS Biol. 2023 Apr 20;21(4):e3002042. doi: 10.1371/journal.pbio.3002042. PMID: 37079504; PMCID: PMC10118125.

7. Levy JH, Ghadimi K, Kizhakkedathu JN, Iba T. What's fishy about protamine? Clinical use, adverse reactions, and potential alternatives. J Thromb Haemost. 2023 Apr 14:S1538-7836(23)00319-7. doi: 10.1016/j.jtha.2023.04.005. Epub ahead of print. PMID: 37062523.

April 17, Pubcrawler Hits:

1. Abazari D, Wild AR, Qiu T, Dickinson BC, Bamji SX. Activity-dependent post-translational regulation of palmitoylating and depalmitoylating enzymes in the hippocampus. J Cell Sci. 2023 Apr 1;136(7):jcs260629. doi: 10.1242/jcs.260629. Epub 2023 Apr 5. PMID: 37039765.

2. Vaikakkara Chithran A, Allan DW, O'Connor TP. Adult expression of Semaphorins and Plexins is essential for motor neuron survival. Sci Rep. 2023 Apr 11;13(1):5894. doi: 10.1038/s41598-023-32943-4. PMID: 37041188; PMCID: PMC10090137.

3. Iu HT, Fong PM, Yam HC, Gao P, Yan B, Lai PM, Tang VY, Li KH, Ma CW, Ng KH, Sze KH, Yang D, Davies J, Kao RY. Identification of a Small Molecule Compound Active against Antibiotic-Tolerant Staphylococcus aureus by Boosting ATP Synthesis. Int J Mol Sci. 2023 Mar 26;24(7):6242. doi: 10.3390/ijms24076242. PMID: 37047217; PMCID: PMC10094146.

4. Magenheim J, Maestro MA, Sharon N, Herrera PL, Murtaugh LC, Kopp J, Sander M, Gu G, Melton DA, Ferrer J, Dor Y. Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors. Cell Stem Cell. 2023 Apr 6;30(4):488-497.e3. doi: 10.1016/j.stem.2023.03.003. PMID: 37028408.

5. Clephane K, O'Loughlin JI, Bodnar TS, Wilson MC, Stariha JT, Craig AN, Weinberg J, Brotto LA, Lorenz TK. Lack of Evidence for a Relationship Between Salivary CRP and Women's Sexual Desire: An Investigation Across Clinical and Healthy Samples. J Sex Med. 2022 May 1;19(5):745-760. doi: 10.1016/j.jsxm.2022.02.007. PMID: 37057561.

6. von Kügelgen A, van Dorst S, Yamashita K, Sexton DL, Tocheva EI, Murshudov G, Alva V, Bharat TAM. Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2215808120. doi: 10.1073/pnas.2215808120. Epub 2023 Apr 12. PMID: 37043530.

7. Palmer M, Covington JK, Zhou EM, Thomas SC, Habib N, Seymour CO, Lai D, Johnston J, Hashimi A, Jiao JY, Muok AR, Liu L, Xian WD, Zhi XY, Li MM, Silva LP, Bowen BP, Louie K, Briegel A, Pett-Ridge J, Weber PK, Tocheva EI, Woyke T, Northen TR, Mayali X, Li WJ, Hedlund BP. Thermophilic Dehalococcoidia with unusual traits shed light on an unexpected past. ISME J. 2023 Apr 11. doi: 10.1038/s41396-023-01405-0. Epub ahead of print. PMID: 37041326.

8. Nandan D, Chen E, Chang F, Moon KM, Foster LJ, Reiner N. Comprehensive proteomic analysis of autophagosomes derived from Leishmania-infected macrophages. PLoS One. 2023 Apr 7;18(4):e0284026. doi: 10.1371/journal.pone.0284026. PMID: 37027358; PMCID: PMC10081754.

April 10, Pubcrawler Hits:

1. Mohamed YF, Manivannan K, Fernandez RC. Bordetella pertussis. Trends Microbiol. 2023 Apr 4:S0966-842X(23)00092-6. doi: 10.1016/j.tim.2023.03.012. Epub ahead of print. PMID: 37024321.

2. Schrenk S, Bischoff LJ, Goines J, Cai Y, Vemaraju S, Odaka Y, Good SR, Palumbo JS, Szabo S, Reynaud D, Van Raamsdonk CD, Lang RA, Boscolo E. MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ. Nat Commun. 2023 Apr 6;14(1):1929. doi: 10.1038/s41467-023-37516-7. PMID: 37024491; PMCID: PMC10079932.

April 3, Pubcrawler Hits:

1. Kwan JZJ, Nguyen TF, Uzozie AC, Budzynski MA, Cui J, Lee JMC, Van Petegem F, Lange PF, Teves SS. RNA Polymerase II transcription independent of TBP. Elife. 2023 Mar 30;12:e83810. doi: 10.7554/eLife.83810. Epub ahead of print. PMID: 36995326.

2. Ho KYL, Carr RL, Dvoskin AD, Tanentzapf G. Kinetics of blood cell differentiation during hematopoiesis revealed by quantitative long-term live imaging. Elife. 2023 Mar 31;12:e84085. doi: 10.7554/eLife.84085. PMID: 37000163; PMCID: PMC10065797.

3. Burckhardt JC, Chong DHY, Pett N, Tropini C. Gut commensal Enterocloster species host inoviruses that are secreted in vitro and in vivo. Microbiome. 2023 Mar 30;11(1):65. doi: 10.1186/s40168-023-01496-z. PMID: 36991500; PMCID: PMC10061712.

4. El Zawily A, Vizeacoumar FS, Dahiya R, Banerjee SL, Bhanumathy KK, Elhasasna H, Hanover G, Sharpe JC, Sanchez MG, Greidanus P, Stacey RG, Moon KM, Alexandrov I, Himanen JP, Nikolov DB, Fonge H, White AP, Foster LJ, Wang B, Toosi BM, Bisson N, Mirzabekov TA, Vizeacoumar FJ, Freywald A. A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy. Clin Cancer Res. 2023 Mar 28:OF1-OF16. doi: 10.1158/1078-0432.CCR-22-2535. Epub ahead of print. PMID: 36976175.

March 27, Pubcrawler Hits:

1. Meulewaeter S, Nuytten G, Cheng MHY, De Smedt SC, Cullis PR, De Beer T, Lentacker I, Verbeke R. Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures. J Control Release. 2023 Mar 21:S0168-3659(23)00206-7. doi: 10.1016/j.jconrel.2023.03.039. Epub ahead of print. PMID: 36958400.

2. Cloherty AP, Rader AG, Patel KS, Perez-Vargas J, Thompson CA, Ennis S, Niikura M, Wildenberg ME, Muncan V, Schreurs RR, Jean F, Ribeiro CM. Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade. Emerg Microbes Infect. 2023 Mar 23:2195020. doi: 10.1080/22221751.2023.2195020. Epub ahead of print. PMID: 36951188.

3. Mastracci TL, Apte M, Amundadottir LT, Alvarsson A, Artandi S, Bellin MD, Bernal-Mizrachi E, Caicedo A, Campbell-Thompson M, Cruz-Monserrate Z, El Ouaamari A, Gaulton KJ, Geisz A, Goodarzi MO, Hara M, Hull-Meichle RL, Kleger A, Klein AP, Kopp JL, Kulkarni RN, Muzumdar MD, Naren AP, Oakes SA, Olesen SS, Phelps EA, Powers AC, Stabler CL, Tirkes T, Whitcomb DC, Yadav D, Yong J, Zaghloul NA, Pandol SJ, Sander M. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes. 2023 Apr 1;72(4):433-448. doi: 10.2337/db22-0942. PMID: 36940317; PMCID: PMC10033248.

4. Danby PM, Jeong A, Sim L, Sweeney RP, Wardman JF, Karimi R, Geissner A, Worrall LJ, Reid JP, Strynadka NCJ, Withers S. Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors. Angew Chem Int Ed Engl. 2023 Mar 20:e202301258. doi: 10.1002/anie.202301258. Epub ahead of print. PMID: 36940280.

5. Cikes D, Elsayad K, Sezgin E, Koitai E, Ferenc T, Orthofer M, Yarwood R, Heinz LX, Sedlyarov V, Miranda ND, Taylor A, Grapentine S, Al-Murshedi F, Abot A, Weidinger A, Kutchukian C, Sanchez C, Cronin SJF, Novatchkova M, Kavirayani A, Schuetz T, Haubner B, Haas L, Hagelkruys A, Jackowski S, Kozlov A, Jacquemond V, Knauf C, Superti-Furga G, Rullman E, Gustafsson T, McDermot J, Lowe M, Radak Z, Chamberlain JS, Bakovic M, Banka S, Penninger JM. PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing. Nat Metab. 2023 Mar 20. doi: 10.1038/s42255-023-00766-2. Epub ahead of print. PMID: 36941451.

6. Karlikow M, Amalfitano E, Yang X, Doucet J, Chapman A, Mousavi PS, Homme P, Sutyrina P, Chan W, Lemak S, Yakunin AF, Dolezal AG, Kelley S, Foster LJ, Harpur BA, Pardee K. CRISPR-induced DNA reorganization for multiplexed nucleic acid detection. Nat Commun. 2023 Mar 17;14(1):1505. doi: 10.1038/s41467-023-36874-6. PMID: 36932065; PMCID: PMC10022571.

March 20, Pubcrawler Hits:

1. Muñoz-Gómez SA, Cadena LR, Gardiner AT, Leger MM, Sheikh S, Connell LB, Bilý T, Kopejtka K, Beatty JT, Koblížek M, Roger AJ, Slamovits CH, Lukeš J, Hashimi H. Intracytoplasmic-membrane development in alphaproteobacteria involves the homolog of the mitochondrial crista-developing protein Mic60. Curr Biol. 2023 Mar 8:S0960-9822(23)00199-9. doi: 10.1016/j.cub.2023.02.059. Epub ahead of print. PMID: 36921606.

2. Weisser NE, Sanches M, Escobar-Cabrera E, O'Toole J, Whalen E, Chan PWY, Wickman G, Abraham L, Choi K, Harbourne B, Samiotakis A, Rojas AH, Volkers G, Wong J, Atkinson CE, Baardsnes J, Worrall LJ, Browman D, Smith EE, Baichoo P, Cheng CW, Guedia J, Kang S, Mukhopadhyay A, Newhook L, Ohrn A, Raghunatha P, Zago-Schmitt M, Schrag JD, Smith J, Zwierzchowski P, Scurll JM, Fung V, Black S, Strynadka NCJ, Gold MR, Presta LG, Ng G, Dixit S. An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity. Nat Commun. 2023 Mar 13;14(1):1394. doi: 10.1038/s41467-023-37029-3. PMID: 36914633; PMCID: PMC10011572.

3. Sadasivan J, Hyrina A, DaSilva R, Jan E. An insect viral protein disrupts stress granule formation in mammalian cells. J Mol Biol. 2023 Mar 8:168042. doi: 10.1016/j.jmb.2023.168042. Epub ahead of print. PMID: 36898623.

4. Richard Albert J, Kobayashi T, Inoue A, Monteagudo-Sánchez A, Kumamoto S, Takashima T, Miura A, Oikawa M, Miura F, Takada S, Hirabayashi M, Korthauer K, Kurimoto K, Greenberg MVC, Lorincz M, Kobayashi H. Conservation and divergence of canonical and non-canonical imprinting in murids. Genome Biol. 2023 Mar 14;24(1):48. doi: 10.1186/s13059-023-02869-1. PMID: 36918927; PMCID: PMC10012579.

5. Gignac SJ, MacCharles KR, Fu K, Bonaparte K, Akarsu G, Barrett TW, Verheyen EM, Richman JM. Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow Syndrome. Dis Model Mech. 2023 Mar 14:dmm.049844. doi: 10.1242/dmm.049844. Epub ahead of print. PMID: 36916233.

6. Garland O, Ton AT, Moradi S, Smith JR, Kovacic S, Ng K, Pandey M, Ban F, Lee J, Vuckovic M, Worrall LJ, Young RN, Pantophlet R, Strynadka NCJ, Cherkasov A. Large-Scale Virtual Screening for the Discovery of SARS-CoV-2 Papain-like Protease (PLpro) Non-covalent Inhibitors. J Chem Inf Model. 2023 Mar 17. doi: 10.1021/acs.jcim.2c01641. Epub ahead of print. PMID: 36930801.

7. Matos I, Barvalia M, Chehal MK, Robertson AG, Kulic I, Silva JAFD, Ranganathan A, Short A, Huang YH, Long E, Priatel JJ, Dhanji S, Nelson BH, Krebs DL, Harder KW. Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling. Cancer Res Commun. 2023 Mar 9;3(3):404-419. doi: 10.1158/2767-9764.CRC-22-0278. PMID: 36911097; PMCID: PMC9997410.

March 13, Pubcrawler Hits:

1. Kreida S, Narita A, Johnson MD, Tocheva EI, Das A, Ghosal D, Jensen GJ. Cryo-EM structure of the Agrobacterium tumefaciens T4SS-associated T-pilus reveals stoichiometric protein-phospholipid assembly. Structure. 2023 Feb 23:S0969-2126(23)00039-4. doi: 10.1016/j.str.2023.02.005. Epub ahead of print. PMID: 36870333.

2. Sullivan KE, Kraus L, Kapustina M, Wang L, Stach TR, Lemire AL, Clements J, Cembrowski MS. Sharp cell-type-identity changes differentiate the retrosplenial cortex from the neocortex. Cell Rep. 2023 Mar 6;42(3):112206. doi: 10.1016/j.celrep.2023.112206. Epub ahead of print. PMID: 36881508.

3. Balzarini M, Yuan Z, Weidberg H. MitoStores: a place for precursors to ride out the storm. EMBO J. 2023 Mar 6:e113576. doi: 10.15252/embj.2023113576. Epub ahead of print. PMID: 36876922.

4. Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP. Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice. Sci Rep. 2023 Mar 7;13(1):3811. doi: 10.1038/s41598-023-30794-7. PMID: 36882463; PMCID: PMC9992365.

March 6, Pubcrawler Hits:

1. Mo Y, Cheng MHY, D'Elia A, Doran K, Ding L, Chen J, Cullis PR, Zheng G. Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid Nanoparticles. ACS Nano. 2023 Feb 28. doi: 10.1021/acsnano.2c10936. Epub ahead of print. PMID: 36853331.

2. Baker JA, Bodnar TS, Breit KR, Weinberg J, Thomas JD. Choline Supplementation Alters Hippocampal Cytokine Levels in Adolescence and Adulthood in an Animal Model of Fetal Alcohol Spectrum Disorders. Cells. 2023 Feb 8;12(4):546. doi: 10.3390/cells12040546. PMID: 36831213; PMCID: PMC9953782.

3. Rathinaswamy MK, Jenkins ML, Duewell BR, Zhang X, Harris NJ, Evans JT, Stariha JTB, Dalwadi U, Fleming KD, Ranga-Prasad H, Yip CK, Williams RL, Hansen SD, Burke JE. Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs. Cell Rep. 2023 Feb 25;42(3):112172. doi: 10.1016/j.celrep.2023.112172. Epub ahead of print. PMID: 36842083.

February 27, Pubcrawler Hits:

1. Das M, Cheng D, Matzat T, Auld VJ. Innexin-mediated adhesion between glia is required for axon ensheathment in the peripheral nervous system. J Neurosci. 2023 Feb 16:JN-RM-1323-22. doi: 10.1523/JNEUROSCI.1323-22.2023. Epub ahead of print. PMID: 36801823.

2. Zhigaltsev IV, Cullis PR. Morphological Behavior of Liposomes and Lipid Nanoparticles. Langmuir. 2023 Feb 22. doi: 10.1021/acs.langmuir.2c02794. Epub ahead of print. PMID: 36812413.

3. Abrahamyan A, Eldstrom J, Sahakyan H, Karagulyan N, Mkrtchyan L, Karapetyan T, Sargsyan E, Kneussel M, Nazaryan K, Schwarz JR, Fedida D, Vardanyan V. Mechanism of external K+ sensitivity of KCNQ1 channels. J Gen Physiol. 2023 May 1;155(5):e202213205. doi: 10.1085/jgp.202213205. Epub 2023 Feb 21. PMID: 36809486; PMCID: PMC9960071.

4. Morgan-Lang C, Hallam SJ. A Guide to Gene-Centric Analysis Using TreeSAPP. Curr Protoc. 2023 Feb;3(2):e671. doi: 10.1002/cpz1.671. PMID: 36801973.

5. Yazdani-Ahmadabadi H, Yu K, Khoddami S, F Felix D, Yeh HH, Luo HD, Moskalev I, Wang Q, Wang R, Grecov D, Fazli L, Lange D, Kizhakkedathu JN. Robust Nanoparticle-Derived Lubricious Antibiofilm Coating for Difficult-to-Coat Medical Devices with Intricate Geometry. ACS Nanosci Au. 2022 Oct 28;3(1):67-83. doi: 10.1021/acsnanoscienceau.2c00040. PMID: 36820095; PMCID: PMC9936578.

February 20, Pubcrawler Hits:

1. Akbari V, Hanlon VCT, O'Neill K, Lefebvre L, Schrader KA, Lansdorp PM, Jones SJM. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq. Cell Genom. 2022 Dec 21;3(1):100233. doi: 10.1016/j.xgen.2022.100233. PMID: 36777186; PMCID: PMC9903809.

2. Salewskij K, Penninger JM. Blood Vessel Organoids for Development and Disease. Circ Res. 2023 Feb 17;132(4):498-510. doi: 10.1161/CIRCRESAHA.122.321768. Epub 2023 Feb 16. PMID: 36795852.

3. Oudit GY, Wang K, Viveiros A, Kellner MJ, Penninger JM. Angiotensin-converting enzyme 2-at the heart of the COVID-19 pandemic. Cell. 2023 Feb 2:S0092-8674(23)00098-3. doi: 10.1016/j.cell.2023.01.039. Epub ahead of print. PMID: 36787743; PMCID: PMC9892333.

4. Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H. Data for assessing red blood cell deformability from microscopy images using deep learning. Data Brief. 2023 Jan 25;47:108928. doi: 10.1016/j.dib.2023.108928. PMID: 36798597; PMCID: PMC9926190.

5. Liu Y, Wilson AJ, Han J, Hui A, O'Sullivan L, Huan T, Haney CH. Amino Acid Availability Determines Plant Immune Homeostasis in the Rhizosphere Microbiome. mBio. 2023 Feb 14:e0342422. doi: 10.1128/mbio.03424-22. Epub ahead of print. PMID: 36786577.

February 13, Pubcrawler Hits:

1. Wild AR, Hogg PW, Flibotte S, Kochhar S, Hollman RB, Haas K, Bamji SX. CellPalmSeq: A curated RNAseq database of palmitoylating and de-palmitoylating enzyme expression in human cell types and laboratory cell lines. Front Physiol. 2023 Jan 24;14:1110550. doi: 10.3389/fphys.2023.1110550. PMID: 36760531; PMCID: PMC9904442.

2. Morse ZJ, Simister RL, Crowe SA, Horwitz MS, Osborne LC. Virus induced dysbiosis promotes type 1 diabetes onset. Front Immunol. 2023 Jan 19;14:1096323. doi: 10.3389/fimmu.2023.1096323. PMID: 36742327; PMCID: PMC9892191.

3. Hall LG, Thyfault JP, Johnson JD. Exercise and inactivity as modifiers of beta cell function and type 2 diabetes risk. J Appl Physiol (1985). 2023 Feb 9. doi: 10.1152/japplphysiol.00472.2022. Epub ahead of print. PMID: 36759159.

4. Saber N, Ellis CE, Iworima DG, Baker RK, Rezania A, Kieffer TJ. The impact of different implantation sites and sex on the differentiation of human pancreatic endoderm cells into insulin-secreting cells in vivo. Diabetes. 2023 Feb 6:db220692. doi: 10.2337/db22-0692. Epub ahead of print. PMID: 36745576.

5. Werschler N, Penninger J. Generation of Human Blood Vessel Organoids from Pluripotent Stem Cells. J Vis Exp. 2023 Jan 20;(191). doi: 10.3791/64715. PMID: 36744771.

6. Taubenschmid-Stowers J, Orthofer M, Laemmerer A, Krauditsch C, Rózsová M, Studer C, Lötsch D, Gojo J, Gabler L, Dyczynski M, Efferth T, Hagelkruys A, Widhalm G, Peyrl A, Spiegl-Kreinecker S, Hoepfner D, Bian S, Berger W, Knoblich JA, Elling U, Horn M, Penninger JM. A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors. EMBO Mol Med. 2023 Feb 6:e16959. doi: 10.15252/emmm.202216959. Epub ahead of print. PMID: 36740985.

February 6, Pubcrawler Hits:

1. Leung CLK, Karunakaran S, Atser MG, Innala L, Hu X, Viau V, Johnson JD, Clee SM. Analysis of a genetic region affecting mouse body weight. Physiol Genomics. 2023 Jan 30. doi: 10.1152/physiolgenomics.00137.2022. Epub ahead of print. PMID: 36717164.

2. Taubenschmid-Stowers J, Orthofer M, Laemmerer A, Krauditsch C, Rózsová M, Studer C, Lötsch D, Gojo J, Gabler L, Dyczynski M, Efferth T, Hagelkruys A, Widhalm G, Peyrl A, Spiegl-Kreinecker S, Hoepfner D, Bian S, Berger W, Knoblich JA, Elling U, Horn M, Penninger JM. A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors. EMBO Mol Med. 2023 Feb 6:e16959. doi: 10.15252/emmm.202216959. Epub ahead of print. PMID: 36740985.

3. Yamada D, Kojima Y, Hosoya A, Suzuki M, Watabe T, Inoue T, Tsugawa N, Asakawa T, Yonemoto Y, Onizawa M, Nemoto Y, Oshima S, Shimonaka M, Kuba K, Ishida J, Fukamizu A, Penninger JM, Watanabe M, Okamoto R, Nagaishi T. Apelin expression is downregulated in T cells in a murine model of chronic colitis. Biochem Biophys Res Commun. 2023 Jan 21;647:72-79. doi: 10.1016/j.bbrc.2023.01.068. Epub ahead of print. PMID: 36731336.

4. Wang J, An M, Haubner BJ, Penninger JM. Cardiac regeneration: Options for repairing the injured heart. Front Cardiovasc Med. 2023 Jan 12;9:981982. doi: 10.3389/fcvm.2022.981982. PMID: 36712238; PMCID: PMC9877631.

5. McNutt ZA, Roy B, Gemler BT, Shatoff EA, Moon KM, Foster LJ, Bundschuh R, Fredrick K. Ribosomes lacking bS21 gain function to regulate protein synthesis in Flavobacterium johnsoniae. Nucleic Acids Res. 2023 Feb 2:gkad047. doi: 10.1093/nar/gkad047. Epub ahead of print. PMID: 36727479.

6. Maysinger D, Zhang I, Wu PY, Kagelmacher M, Luo HD, Kizhakkedathu JN, Dernedde J, Ballauff M, Haag R, Shobo A, Multhaup G, McKinney RA. Sulfated Hyperbranched and Linear Polyglycerols Modulate HMGB1 and Morphological Plasticity in Neural Cells. ACS Chem Neurosci. 2023 Jan 30. doi: 10.1021/acschemneuro.2c00558. Epub ahead of print. PMID: 36717083.

January 30, Pubcrawler Hits:

1. Behroozian S, Zlosnik JEA, Xu W, Li LY, Davies JE. Antibacterial Activity of a Natural Clay Mineral against Burkholderia cepacia Complex and Other Bacterial Pathogens Isolated from People with Cystic Fibrosis. Microorganisms. 2023 Jan 6;11(1):150. doi: 10.3390/microorganisms11010150. PMID: 36677442; PMCID: PMC9862493.

2. Brownrigg GP, Xia YH, Jamie Chu CM, Wang S, Chao C, Zhang JA, Skovsø S, Panzhinskiy E, Hu X, Johnson JD, Rideout EJ. Sex differences in islet stress responses support female β cell resilience. Mol Metab. 2023 Jan 20:101678. doi: 10.1016/j.molmet.2023.101678. Epub ahead of print. PMID: 36690328.

3. Puumala LS, Grist SM, Morales JM, Bickford JR, Chrostowski L, Shekhar S, Cheung KC. Biofunctionalization of Multiplexed Silicon Photonic Biosensors. Biosensors (Basel). 2022 Dec 29;13(1):53. doi: 10.3390/bios13010053. PMID: 36671887; PMCID: PMC9855810.

4. Horvath RM, Dahabieh M, Malcolm T, Sadowski I. TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation. Commun Biol. 2023 Jan 23;6(1):86. doi: 10.1038/s42003-023-04484-z. PMID: 36690785; PMCID: PMC9870992.

January 23, Pubcrawler Hits:

1. Kurashina M, Mizumoto K. Targeting endogenous proteins for spatial and temporal knockdown using auxin-inducible degron in Caenorhabditis elegans. STAR Protoc. 2023 Jan 13;4(1):102028. doi: 10.1016/j.xpro.2022.102028. Epub ahead of print. PMID: 36640369.

2. Haage A, Tanentzapf G. Analysis of Integrin-Dependent Melanoblast Migration During Development. Methods Mol Biol. 2023;2608:207-221. doi: 10.1007/978-1-0716-2887-4_13. PMID: 36653710.

January 16, Pubcrawler Hits:

1. Inkster AM, Wong MT, Matthews AM, Brown CJ, Robinson WP. Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data. Epigenetics Chromatin. 2023 Jan 7;16(1):1. doi: 10.1186/s13072-022-00477-0. PMID: 36609459; PMCID: PMC9825011.

2. Qiu Y, Noonan AJC, Dofher K, Koch M, Kieft B, Lin X, Ziels RM, Hallam SJ. Complete Genome Sequence of Phormidium yuhuli AB48, Isolated from an Industrial Photobioreactor Environment. Microbiol Resour Announc. 2023 Jan 10:e0075922. doi: 10.1128/mra.00759-22. Epub ahead of print. PMID: 36625650.

3. Taylor AJ, Panzhinskiy E, Orban PC, Lynn FC, Schaeffer DF, Johnson JD, Kopp JL, Verchere CB. Islet amyloid polypeptide does not suppress pancreatic cancer. Mol Metab. 2023 Jan 5:101667. doi: 10.1016/j.molmet.2023.101667. Epub ahead of print. PMID: 36621763.

4. Mizumoto K, Jin Y, Bessereau JL. Synaptogenesis: unmasking molecular mechanisms using Caenorhabditis elegans. Genetics. 2023 Jan 11:iyac176. doi: 10.1093/genetics/iyac176. Epub ahead of print. PMID: 36630525.

5. Liu Q, Telezhkin V, Jiang W, Gu Y, Wang Y, Hong W, Tian W, Yarova P, Zhang G, Lee SM, Zhang P, Zhao M, Allen ND, Hirsch E, Penninger J, Song B. Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation. Cell Biosci. 2023 Jan 9;13(1):4. doi: 10.1186/s13578-023-00954-3. PMID: 36624495; PMCID: PMC9830810.

6. Horvath RM, Brumme ZL, Sadowski I. Inhibition of the TRIM24 bromodomain reactivates latent HIV-1. Sci Rep. 2023 Jan 11;13(1):556. doi: 10.1038/s41598-023-27765-3. PMID: 36631514; PMCID: PMC9832417.

7. Maroilley T, Flibotte S, Jean F, Rodrigues Alves Barbosa V, Galbraith A, Chida AR, Cotra F, Li X, Oncea L, Edgley M, Moerman DG, Tarailo-Graovac M. Genome sequencing of C. elegans balancer strains reveals previously unappreciated complex genomic rearrangements. Genome Res. 2022 Dec 5:gr.276988.122. doi: 10.1101/gr.276988.122. Epub ahead of print. PMID: 36617680.

January 9, Pubcrawler Hits:

1. Brown KL, Wilburn KM, Montague CR, Grigg JC, Sanz O, Pérez-Herrán E, Barros D, Ballell L, VanderVen BC, Eltis LD. Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in Mycobacterium tuberculosis by the Novel Drug Candidate GSK2556286. Antimicrob Agents Chemother. 2023 Jan 5:e0129422. doi: 10.1128/aac.01294-22. Epub ahead of print. PMID: 36602336.

2. De Silva E, Hong F, Falet H, Kim H. Filamin A in platelets: Bridging the (signaling) gap between the plasma membrane and the actin cytoskeleton. Front Mol Biosci. 2022 Dec 20;9:1060361. doi: 10.3389/fmolb.2022.1060361. PMID: 36605989; PMCID: PMC9808056.

3. Alexander JAN, Worrall LJ, Hu J, Vuckovic M, Satishkumar N, Poon R, Sobhanifar S, Rosell FI, Jenkins J, Chiang D, Mosimann WA, Chambers HF, Paetzel M, Chatterjee SS, Strynadka NCJ. Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. Nature. 2023 Jan 4. doi: 10.1038/s41586-022-05583-3. Epub ahead of print. PMID: 36599987.

4. Garreta E, Moya-Rull D, Stanifer ML, Monteil V, Prado P, Marco A, Tarantino C, Gallo M, Jonsson G, Hagelkruys A, Mirazimi A, Boulant S, Penninger JM, Montserrat N. Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cells. STAR Protoc. 2022 Dec 16;3(4):101872. doi: 10.1016/j.xpro.2022.101872. Epub 2022 Nov 7. PMID: 36595951; PMCID: PMC9637521.

5. Du C, Jayo R, Mendelson AA, Chafeeva I, Roza GD, Liggins R, Kizhakkedathu JN. Pharmacokinetics of small hyperbranched polyglycerols as an osmotic agent for peritoneal dialysis: Plasma exposure, organ distribution and excretion in rats. Perit Dial Int. 2023 Jan 1:8968608221144856. doi: 10.1177/08968608221144856. Epub ahead of print. PMID: 36588412.

January 2, Pubcrawler Hits:

1. Bauer KW, McKenzie NR, Bottini C, Erba E, Crowe SA. Carbon pump dynamics and limited organic carbon burial during OAE1a. Geobiology. 2022 Dec 25. doi: 10.1111/gbi.12538. Epub ahead of print. PMID: 36567458.

2. Cardoen B, Wong T, Alan P, Lee S, Matsubara JA, Nabi IR, Hamarneh G. SPECHT: Self-tuning Plausibility based object detection Enables quantification of Conflict in Heterogeneous multi-scale microscopy. PLoS One. 2022 Dec 29;17(12):e0276726. doi: 10.1371/journal.pone.0276726. PMID: 36580473; PMCID: PMC9799313.

3. Zhu R, Canena D, Sikora M, Klausberger M, Seferovic H, Mehdipour AR, Hain L, Laurent E, Monteil V, Wirnsberger G, Wieneke R, Tampé R, Kienzl NF, Mach L, Mirazimi A, Oh YJ, Penninger JM, Hummer G, Hinterdorfer P. Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level. Nat Commun. 2022 Dec 24;13(1):7926. doi: 10.1038/s41467-022-35641-3. PMID: 36566234; PMCID: PMC9789309.


December 26, Pubcrawler Hits:

1. Werner AZ, Eltis LD. Tandem chemocatalysis and biological funneling to valorize lignin. Trends Biotechnol. 2022 Dec 17:S0167-7799(22)00312-2. doi: 10.1016/j.tibtech.2022.12.004. Epub ahead of print. PMID: 36535815.

2. Fatton M, Filippidou S, Junier T, Cailleau G, Berge M, Poppleton D, Blum TB, Kaminek M, Odriozola A, Blom J, Johnson SL, Abrahams JP, Chain PS, Gribaldo S, Tocheva EI, Zuber B, Viollier PH, Junier P. Cryptosporulation in Kurthia spp. forces a rethinking of asporogenesis in Firmicutes. Environ Microbiol. 2022 Dec;24(12):6320-6335. doi: 10.1111/1462-2920.16145. Epub 2022 Aug 17. PMID: 36530021.

December 19, Pubcrawler Hits:

1. Peters V, Deretic N, Choi K, Gold MR. ERK contributes to B cell receptor-induced cell spreading in the A20 mouse B cell line. MicroPubl Biol. 2022 Nov 23;2022:10.17912/micropub.biology.000665. doi: 10.17912/micropub.biology.000665. PMID: 36506348; PMCID: PMC9729986.

2. Shapira T, Vimalanathan S, Rens C, Pichler V, Peña-Díaz S, Jordana G, Rees W, Winkler DFH, Sarai I, Steiner T, Jean F, Pelech S, Av-Gay Y. Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication. Mol Biomed. 2022 Dec 12;3(1):43. doi: 10.1186/s43556-022-00111-1. PMID: 36508083; PMCID: PMC9742639.

3. Pérez-Vargas J, Shapira T, Olmstead AD, Villanueva I, Thompson CAH, Ennis S, Gao G, DeGuzman J, Williams DE, Wang M, Chin A, Bautista-Sánchez D, Agafitei O, Levett P, Xie X, Nuzzo G, Freire VF, Quintana-Bulla JI, Bernardi DI, Gubiani JR, Suthiphasilp V, Raksat A, Meesakul P, Polbuppha I, Cheenpracha S, Jaidee W, Kanokmedhakul K, Yenjai C, Chaiyosang B, Teles HL, Manzo E, Fontana A, Leduc R, Boudreault PL, Berlinck RGS, Laphookhieo S, Kanokmedhakul S, Tietjen I, Cherkasov A, Krajden M, Nabi IR, Niikura M, Shi PY, Andersen RJ, Jean F. Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics. Antiviral Res. 2022 Dec 8:105484. doi: 10.1016/j.antiviral.2022.105484. Epub ahead of print. PMID: 36503013; PMCID: PMC9729583.

4. Paul M, Golla K, Kim H. Gelsolin Modulates Platelet Dense Granule Secretion and Hemostasis via the Actin Cytoskeleton. Thromb Haemost. 2022 Dec 15. doi: 10.1055/s-0042-1758800. Epub ahead of print. PMID: 36522181.

5. Jiang SZ, To JL, Hughes MR, McNagny KM, Kim H. Platelet signaling at the nexus of innate immunity and rheumatoid arthritis. Front Immunol. 2022 Nov 25;13:977828. doi: 10.3389/fimmu.2022.977828. PMID: 36505402; PMCID: PMC9732516.

6. Nasseri SS, Siren EMJ, Kizhakkedathu JN, Cheung K. HyClear: A Novel Tissue Clearing Solution for One-Step Clearing of Microtissues. Cells. 2022 Nov 30;11(23):3854. doi: 10.3390/cells11233854. PMID: 36497111; PMCID: PMC9738288.

7. Wiesmann CL, Wang NR, Zhang Y, Liu Z, Haney CH. Origins of symbiosis: shared mechanisms underlying microbial pathogenesis, commensalism and mutualism of plants and animals. FEMS Microbiol Rev. 2022 Dec 15:fuac048. doi: 10.1093/femsre/fuac048. Epub ahead of print. PMID: 36521845.

8. Belanger CR, Dostert M, Blimkie TM, Lee AH, Dhillon BK, Wu BC, Akhoundsadegh N, Rahanjam N, Castillo-Arnemann J, Falsafi R, Pletzer D, Haney CH, Hancock REW. Surviving the host: Microbial metabolic genes required for growth of Pseudomonas aeruginosa in physiologically-relevant conditions. Front Microbiol. 2022 Nov 25;13:1055512. doi: 10.3389/fmicb.2022.1055512. PMID: 36504765; PMCID: PMC9732424.

December 12, Pubcrawler Hits:

1. Nasseri GG, Matin N, Wild AR, Tosefsky K, Flibotte S, Stacey RG, Hollman RB, Foster LJ, Bamji SX. Synaptic activity-dependent changes in the hippocampal palmitoylome. Sci Signal. 2022 Dec 6;15(763):eadd2519. doi: 10.1126/scisignal.add2519. Epub 2022 Dec 6. PMID: 36473050.

2. Devine DV. Novel platelet products including cold-stored platelets. Hematology Am Soc Hematol Educ Program. 2022 Dec 9;2022(1):421-423. doi: 10.1182/hematology.2022000400. PMID: 36485096.

3. Mouat IC, Shanina I, Horwitz MS. Age-associated B cells are long-lasting effectors that impede latent γHV68 reactivation. Sci Rep. 2022 Dec 7;12(1):21189. doi: 10.1038/s41598-022-25543-1. PMID: 36477199.

4. Brassard J, Hughes MR, Roskelley CD, McNagny KM. Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes. Front Biosci (Landmark Ed). 2022 Nov 4;27(11):301. doi: 10.31083/j.fbl2711301. PMID: 36472102.

5. Prieto MD, Jang J, Franciosi AN, Av-Gay Y, Bach H, Tebbutt SJ, Quon BS. Whole blood RNA-seq demonstrates an increased host immune response in individuals with cystic fibrosis who develop nontuberculous mycobacterial pulmonary disease. PLoS One. 2022 Dec 8;17(12):e0278296. doi: 10.1371/journal.pone.0278296. PMID: 36480571.

6. Onji M, Penninger JM. RANKL and RANK in Cancer Therapy. Physiology (Bethesda). 2022 Dec 6. doi: 10.1152/physiol.00020.2022. Epub ahead of print. PMID: 36473204.

December 5, Pubcrawler Hits:

1. Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC; Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study. Transfusion. 2022 Dec 1. doi: 10.1111/trf.17200. Epub ahead of print. PMID: 36453841.

2. Sadasivan J, Vlok M, Wang X, Nayak A, Andino R, Jan E. Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation. PLoS Pathog. 2022 Dec 1;18(12):e1010598. doi: 10.1371/journal.ppat.1010598. Epub ahead of print. PMID: 36455064.

3. Postić S, Sarikas S, Pfabe J, Pohorec V, Križančić Bombek L, Sluga N, Skelin Klemen M, Dolenšek J, Korošak D, Stozer A, Evans-Molina C, Johnson JD, Slak Rupnik M. High resolution analysis of the cytosolic Ca2+ events in beta cell collectives in situ. Am J Physiol Endocrinol Metab. 2022 Nov 30. doi: 10.1152/ajpendo.00165.2022. Epub ahead of print. PMID: 36449570.

4. Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY. Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models. Nat Commun. 2022 Nov 28;13(1):7335. doi: 10.1038/s41467-022-34990-3. PMID: 36443325; PMCID: PMC9705293.

5. Morales Moreira ZP, Chen MY, Yanez Ortuno DL, Haney CH. Engineering plant microbiomes by integrating eco-evolutionary principles into current strategies. Curr Opin Plant Biol. 2022 Nov 25;71:102316. doi: 10.1016/j.pbi.2022.102316. Epub ahead of print. PMID: 36442442.

November 28, Pubcrawler Hits:

1. Navarro-Cobos MJ, Morales-Guzman SI, Baldry SEL, Brown CJ. Derivation of a minimal functional XIST by combining human and mouse interaction domains. Hum Mol Genet. 2022 Nov 25:ddac285. doi: 10.1093/hmg/ddac285. Epub ahead of print. PMID: 36426827.

2. O'Leary TP, Kendrick RM, Bristow BN, Sullivan KE, Wang L, Clements J, Lemire AL, Cembrowski MS. Neuronal cell types, projections, and spatial organization of the central amygdala. iScience. 2022 Nov 4;25(12):105497. doi: 10.1016/j.isci.2022.105497. PMID: 36425768; PMCID: PMC9678740.

3. Noonan AJC, Qiu Y, Kieft B, Formby S, Liu T, Dofher K, Koch M, Hallam SJ. Metagenome-Assembled Genomes for "Candidatus Phormidium sp. Strain AB48" and Co-occurring Microorganisms from an Industrial Photobioreactor Environment. Microbiol Resour Announc. 2022 Nov 21:e0044722. doi: 10.1128/mra.00447-22. Epub ahead of print. PMID: 36409107.

4. Wiesmann CL, Zhang Y, Alford M, Hamilton CD, Dosanjh M, Thoms D, Dostert M, Wilson A, Pletzer D, Hancock REW, Haney CH. The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species. ISME J. 2022 Nov 24. doi: 10.1038/s41396-022-01343-3. Epub ahead of print. PMID: 36424517.

5. Zayda P. Morales Moreira, Melissa Y. Chen, Daniela L. Yanez Ortuno, Cara H. Haney, Engineering plant microbiomes by integrating eco-evolutionary principles into current strategies, Current Opinion in Plant Biology, Volume 71, 2023,

6. Mouat IC, Allanach JR, Fettig NM, Fan V, Girard AM, Shanina I, Osborne LC, Vorobeychik G, Horwitz MS. Gammaherpesvirus infection drives age-associated B cells toward pathogenicity in EAE and MS. Sci Adv. 2022 Nov 25;8(47):eade6844. doi: 10.1126/sciadv.ade6844. Epub 2022 Nov 25. PMID: 36427301.

7. O'Connor TN, van den Bersselaar LR, Chen YS, Nicolau S, Simon B, Huseth A, Todd JJ, Van Petegem F, Sarkozy A, Goldberg MF, Voermans NC, Dirksen RT; RYR1 Myopathy Consortium. RYR-1-Related Diseases International Research Workshop: From Mechanisms to Treatments Pittsburgh, PA, U.S.A., 21-22 July 2022. J Neuromuscul Dis. 2022 Nov 16. doi: 10.3233/JND-221609. Epub ahead of print. PMID: 36404556.

November 21, Pubcrawler Hits:

1. Kogay R, Koppenhöfer S, Beatty JT, Kuhn JH, Lang AS, Zhaxybayeva O. Formal recognition and classification of gene transfer agents as viriforms. Virus Evol. 2022 Oct 15;8(2):veac100. doi: 10.1093/ve/veac100. PMID: 36381234; PMCID: PMC9662315.

2. Bernelot-Moens R, Beatty JT. DNA Gyrase Inhibitors Increase the Frequency of Bacteriophage-like RcGTA-Mediated Gene Transfer in Rhodobacter capsulatus. Genes (Basel). 2022 Nov 9;13(11):2071. doi: 10.3390/genes13112071. PMID: 36360308.

3. An K, Kurek D, Mahadeo M, Zhang Y, Thewalt JL, Cullis PR, Kulkarni JA. On the Influence of Nucleic Acid Backbone Modifications on Lipid Nanoparticle Morphology. Langmuir. 2022 Nov 11. doi: 10.1021/acs.langmuir.2c01492. Epub ahead of print. PMID: 36367350.

4. Davenport B, Hallam SJ. Emerging enzyme surface display systems for waste resource recovery. Environ Microbiol. 2022 Nov 12. doi: 10.1111/1462-2920.16284. Epub ahead of print. PMID: 36369958.

5. Warsaba R, Salcedo-Porras N, Flibotte S, Jan E. Expansion of viral genomes with viral protein genome linked copies. Virology. 2022 Nov 11;577:174-184. doi: 10.1016/j.virol.2022.10.012. Epub ahead of print. PMID: 36395539.

6. De Silva E, Paul M, Kim H. Apoptosis in platelets is independent of the actin cytoskeleton. PLoS One. 2022 Nov 15;17(11):e0276584. doi: 10.1371/journal.pone.0276584. PMID: 36378629; PMCID: PMC9665360.

7. Hendi A, Niu LG, Snow AW, Ikegami R, Wang ZW, Mizumoto K. Channel-independent function of UNC-9/Innexin in spatial arrangement of GABAergic synapses in C. elegans. Elife. 2022 Nov 15;11:e80555. doi: 10.7554/eLife.80555. PMID: 36378164; PMCID: PMC9665852.

8. Alan P, Vandevoorde KR, Joshi B, Cardoen B, Gao G, Mohammadzadeh Y, Hamarneh G, Nabi IR. Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS. Cell Mol Life Sci. 2022 Oct 25;79(11):565. doi: 10.1007/s00018-022-04585-8. PMID: 36284011; PMCID: PMC9596570.

9. Chen YS, Van Petegem F. Structural and functional conservation of the activating Ca2+ binding site in inositol 1,4.5-trisphosphate and ryanodine receptors. Cell Calcium. 2022 Nov 5;108:102671. doi: 10.1016/j.ceca.2022.102671. Epub ahead of print. PMID: 36370621.

10. Kalas P, Redfield RJ. Using animations to teach biological processes and principles. PLoS Biol. 2022 Nov 17;20(11):e3001875. doi: 10.1371/journal.pbio.3001875. PMID: 36395079; PMCID: PMC9671341.

November 7, Pubcrawler Hits:

1. Accili E. When Is a Potassium Channel Not a Potassium Channel? Function (Oxf). 2022 Oct 7;3(6):zqac052. doi: 10.1093/function/zqac052. PMID: 36325512; PMCID: PMC9614928.

2. Sun E, König SG, Cirstea M, Hallam SJ, Graves ML, Oliver DC. Development of a data science CURE in microbiology using publicly available microbiome datasets. Front Microbiol. 2022 Oct 12;13:1018237. doi: 10.3389/fmicb.2022.1018237. PMID: 36312919; PMCID: PMC9597637.

3. Le HT, Golla K, Karimi R, Hughes MR, Lakschevitz F, Cines DB, Kowalska MA, Poncz M, McNagny KM, Häkkinen L, Kim H. Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts. Sci Rep. 2022 Nov 3;12(1):18636. doi: 10.1038/s41598-022-19850-w. PMID: 36329090; PMCID: PMC9633774.

4. Omenn GS, Lane L, Overall CM, Pineau C, Packer NH, Cristea IM, Lindskog C, Weintraub ST, Orchard S, Roehrl MHA, Nice E, Liu S, Bandeira N, Chen YJ, Guo T, Aebersold R, Moritz RL, Deutsch EW. The 2022 Report on the Human Proteome from the HUPO Human Proteome Project. J Proteome Res. 2022 Nov 1. doi: 10.1021/acs.jproteome.2c00498. Epub ahead of print. PMID: 36318223.

5. Hagelkruys A, Horrer M, Taubenschmid-Stowers J, Kavirayani A, Novatchkova M, Orthofer M, Pai TP, Cikes D, Zhuk S, Balmaña M, Esk C, Koglgruber R, Moeseneder P, Lazovic J, Zopf LM, Cronin SJF, Elling U, Knoblich JA, Penninger JM. The HUSH complex controls brain architecture and protocadherin fidelity. Sci Adv. 2022 Nov 4;8(44):eabo7247. doi: 10.1126/sciadv.abo7247. Epub 2022 Nov 4. PMID: 36332029.

6. Dostert M, Belanger CR, Pedraz L, Alford MA, Blimkie TM, Falsafi RF, Bains M, Dhillon BK, Haney CH, Lee AH, Hancock REW. BosR: A novel biofilm-specific regulator in Pseudomonas aeruginosa. Front Microbiol. 2022 Oct 13;13:1021021. doi: 10.3389/fmicb.2022.1021021. PMID: 36312952; PMCID: PMC9611778.

7. Taruno A, Gordon MD. Molecular and Cellular Mechanisms of Salt Taste. Annu Rev Physiol. 2022 Nov 4. doi: 10.1146/annurev-physiol-031522-075853. Epub ahead of print. PMID: 36332657.

October 31, Pubcrawler Hits:

1. Li N, Zeller MP, Shih AW, Heddle NM, St John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A. A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma. Transfusion. 2022 Oct 26. doi: 10.1111/trf.17151. Epub ahead of print. PMID: 36285763.

2. Haack AM, Overall CM, Keller UAD. Degradomics technologies in matrisome exploration. Matrix Biol. 2022 Oct 21:S0945-053X(22)00125-1. doi: 10.1016/j.matbio.2022.10.003. Epub ahead of print. PMID: 36280126.

3. Johnson SB, Lingg RT, Skog TD, Hinz DC, Romig-Martin SA, Viau V, Narayanan NS, Radley JJ. Activity in a prefrontal-periaqueductal gray circuit overcomes behavioral and endocrine features of the passive coping stress response. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2210783119. doi: 10.1073/pnas.2210783119. Epub 2022 Oct 28. PMID: 36306326.

4. Puumala LS, Grist SM, Wickremasinghe K, Al-Qadasi MA, Chowdhury SJ, Liu Y, Mitchell M, Chrostowski L, Shekhar S, Cheung KC. An Optimization Framework for Silicon Photonic Evanescent-Field Biosensors Using Sub-Wavelength Gratings. Biosensors (Basel). 2022 Oct 8;12(10):840. doi: 10.3390/bios12100840. PMID: 36290977; PMCID: PMC9599562.

5. Cameron TC, Randhawa A, Grist SM, Bennet T, Hua J, Alde LG, Caffrey TM, Wellington CL, Cheung KC. PDMS Organ-On-Chip Design and Fabrication: Strategies for Improving Fluidic Integration and Chip Robustness of Rapidly Prototyped Microfluidic In Vitro Models. Micromachines (Basel). 2022 Sep 22;13(10):1573. doi: 10.3390/mi13101573. PMID: 36295926; PMCID: PMC9609846.

October 24, Pubcrawler Hits:

1. De Silva E, Devine D, Jan E, Roskelley C, Kim H. Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner. Biochem J. 2022 Oct 14:BCJ20220177. doi: 10.1042/BCJ20220177. Epub ahead of print. PMID: 36239738.

2. Dexter GN, Navas LE, Grigg JC, Bajwa H, Levy-Booth DJ, Liu J, Louie NA, Nasseri SA, Jang SK, Renneckar S, Eltis LD, Mohn WW. Bacterial catabolism of acetovanillone, a lignin-derived compound. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2213450119. doi: 10.1073/pnas.2213450119. Epub 2022 Oct 18. PMID: 36256818.

3. Hassler L, Penninger J, Batlle D. On the essentiality of the angiotensin converting enzyme 2 receptor for SARS-CoV-2 infection and the potential of soluble angiotensin converting enzyme 2 proteins as universal approach for variants causing COVID-19. Clin Transl Med. 2022 Oct;12(10):e1080. doi: 10.1002/ctm2.1080. PMID: 36229914; PMCID: PMC9561165.

October 10, Pubcrawler Hits:

1. Lillie MA, Vogl AW, Gerard SG, Raverty S, Shadwick RE. Retia mirabilia: Protecting the cetacean brain from locomotion-generated blood pressure pulses. Science. 2022 Sep 23;377(6613):1452-1456. doi: 10.1126/science.abn3315. Epub 2022 Sep 22. PMID: 36137023.

2. Chan JF, Oh YJ, Yuan S, Chu H, Yeung ML, Canena D, Chan CC, Poon VK, Chan CC, Zhang AJ, Cai JP, Ye ZW, Wen L, Yuen TT, Chik KK, Shuai H, Wang Y, Hou Y, Luo C, Chan WM, Qin Z, Sit KY, Au WK, Legendre M, Zhu R, Hain L, Seferovic H, Tampé R, To KK, Chan KH, Thomas DG, Klausberger M, Xu C, Moon JJ, Stadlmann J, Penninger JM, Oostenbrink C, Hinterdorfer P, Yuen KY, Markovitz DM. A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo. Cell Rep Med. 2022 Sep 29:100774. doi: 10.1016/j.xcrm.2022.100774. Epub ahead of print. PMID: 36195094; PMCID: PMC9519379.

3. Mischkulnig M, Kiesel B, Rötzer-Pejrimovsky T, Borkovec M, Lang A, Millesi M, Wadiura LI, Hervey-Jumper S, Penninger JM, Berger MS, Widhalm G, Erhart F. The impact of heme biosynthesis regulation on glioma aggressiveness: Correlations with diagnostic molecular markers. Front Mol Neurosci. 2022 Sep 14;15:928355. doi: 10.3389/fnmol.2022.928355. PMID: 36187350; PMCID: PMC9515895.

October 3, Pubcrawler Hits:

1. Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL. National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies. Transfusion. 2022 Sep 28. doi: 10.1111/trf.17092. Epub ahead of print. PMID: 36169155.

2. Crowe AM, Krekhno JMC, Brown KL, Kulkarni JA, Yam KC, Eltis LD. The unusual convergence of steroid catabolic pathways in Mycobacterium abscessus. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2207505119. doi: 10.1073/pnas.2207505119. Epub 2022 Sep 26. PMID: 36161908.

3. Jalily PH, Jalily Hasani H, Fedida D. In Silico Evaluation of Hexamethylene Amiloride Derivatives as Potential Luminal Inhibitors of SARS-CoV-2 E Protein. Int J Mol Sci. 2022 Sep 13;23(18):10647. doi: 10.3390/ijms231810647. PMID: 36142556; PMCID: PMC9503309.

4. Chu CMJ, Modi H, Ellis C, Krentz NAJ, Skovsø S, Zhao YB, Cen H, Noursadeghi N, Panzhinskiy E, Hu X, Dionne DA, Xia YH, Xuan S, Huising MO, Kieffer TJ, Lynn FC, Johnson JD. Dynamic Ins2 Gene Activity Defines β-cell Maturity States. Diabetes. 2022 Sep 28:db211065. doi: 10.2337/db21-1065. Epub ahead of print. PMID: 36170671.

5. Bell PA, Scheuermann S, Renner F, Pan CL, Lu HY, Turvey SE, Bornancin F, Régnier CH, Overall CM. Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates. Comput Struct Biotechnol J. 2022 Aug 19;20:4717-4732. doi: 10.1016/j.csbj.2022.08.021. PMID: 36147669; PMCID: PMC9463181.

6. Pesch YY, Dang V, Fairchild MJ, Islam F, Camp D, Kaur P, Smendziuk CM, Messenberg A, Carr R, McFarlane CR, Musso PY, Van Petegem F, Tanentzapf G. Gap junctions mediate discrete regulatory steps during fly spermatogenesis. PLoS Genet. 2022 Sep 29;18(9):e1010417. doi: 10.1371/journal.pgen.1010417. Epub ahead of print. PMID: 36174062.

7. Gibbs E, Zhao B, Roman A, Plotkin SS, Peng X, Hsueh SCC, Aina A, Wang J, Shyu C, Yip CK, Nam SE, Kaplan JM, Cashman NR. Rational Generation of Monoclonal Antibodies Selective for Pathogenic Forms of Alpha-Synuclein. Biomedicines. 2022 Sep 2;10(9):2168. doi: 10.3390/biomedicines10092168. PMID: 36140270; PMCID: PMC9496384.

8. Chapman A, Amiri E, Han B, McDermott E, Rueppell O, Tarpy DR, Foster LJ, McAfee A. Fertility costs of cryptic viral infections in a model social insect. Sci Rep. 2022 Sep 23;12(1):15857. doi: 10.1038/s41598-022-20330-4. PMID: 36151143; PMCID: PMC9508145.

9. Woodward SE, Vogt SL, Peña-Díaz J, Melnyk RA, Cirstea M, Serapio-Palacios A, Neufeld LMP, Huus KE, Wang MA, Haney CH, Finlay BB. Gastric acid and escape to systemic circulation represent major bottlenecks to host infection by Citrobacter rodentium. ISME J. 2022 Sep 24. doi: 10.1038/s41396-022-01321-9. Epub ahead of print. PMID: 36153406.

September 19, Pubcrawler Hits:

1. Fettig NM, Robinson HG, Allanach JR, Davis KM, Simister RL, Wang EJ, Sharon AJ, Ye J, Popple SJ, Seo JH, Gibson DL, Crowe SA, Horwitz MS, Osborne LC. Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis. Cell Rep. 2022 Sep 13;40(11):111328. doi: 10.1016/j.celrep.2022.111328. PMID: 36103823.

2. Al-Riyami AZ, Estcourt L, Rahimi-Levene N, Bloch EM, Goel R, Tiberghien P, Thibert JB, Bruun MT, Devine DV, Gammon RR, Wendel S, Toungouz Nevessignsky M, Grubovic Rastvorceva RM, Oreh A, Romon I, van den Berg K, Kitazawa J, Patidar G, So-Osman C, Wood EM; ISBT COVID-19 Convalescent Plasma Working Group. Early and out-of-hospital use of COVID-19 convalescent plasma: An international assessment of utilization and feasibility. Vox Sang. 2022 Sep 14. doi: 10.1111/vox.13347. Epub ahead of print. PMID: 36102139.

3. Toews JNC, Philippe TJ, Hill LA, Dordevic M, Miguelez-Crespo A, Homer NZM, Nixon M, Hammond GL, Viau V. Corticosteroid-binding globulin (SERPINA6) establishes postpubertal sex differences in rat adrenal development. Endocrinology. 2022 Sep 16:bqac152. doi: 10.1210/endocr/bqac152. Epub ahead of print. PMID: 36112420.

4. Ramzy A, Belmonte PJ, Braam MJS, Ida S, Wilts EM, Levings MK, Rezania A, Kieffer TJ. A century long journey from the discovery of insulin to the implantation of stem cell derived islets. Endocr Rev. 2022 Sep 16:bnac021. doi: 10.1210/endrev/bnac021. Epub ahead of print. PMID: 36111962.

September 12, Pubcrawler Hits:

1. Al Fayez N, Rouhollahi E, Ong CY, Wu J, Nguyen A, Böttger R, Cullis PR, Witzigmann D, Li SD. Hepatocyte-targeted delivery of imiquimod reduces hepatitis B virus surface antigen. J Control Release. 2022 Sep 7;350:630-641. doi: 10.1016/j.jconrel.2022.08.058. Epub ahead of print. PMID: 36058352.

2. Hamledari H, Asghari P, Jayousi F, Aguirre A, Maaref Y, Barszczewski T, Ser T, Moore E, Wasserman W, Klein Geltink R, Teves S, Tibbits GF. Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation. Front Cardiovasc Med. 2022 Aug 12;9:967659. doi: 10.3389/fcvm.2022.967659. PMID: 36061558; PMCID: PMC9429949.

3. Lee J, Kenward C, Worrall LJ, Vuckovic M, Gentile F, Ton AT, Ng M, Cherkasov A, Strynadka NCJ, Paetzel M. X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun. 2022 Sep 3;13(1):5196. doi: 10.1038/s41467-022-32854-4. PMID: 36057636; PMCID: PMC9440467.

4. Lu PYT, Kirlin AC, Aristizabal MJ, Brewis HT, Lévesque N, Setiaputra DT, Avvakumov N, Benschop JJ, Groot Koerkamp M, Holstege FCP, Krogan NJ, Yip CK, Côté J, Kobor MS. A balancing act: Interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. Genetics. 2022 Sep 6:iyac136. doi: 10.1093/genetics/iyac136. Epub ahead of print. PMID: 36066422.

5. Abbina S, Abbasi U, Gill A, Leitch H, Kizhakkedathu JN. Active transport nanochelators for the reduction of liver iron burden in iron overload. J Control Release. 2022 Sep 1:S0168-3659(22)00579-X. doi: 10.1016/j.jconrel.2022.08.056. Epub ahead of print. PMID: 36058353.

September 5, Pubcrawler Hits:

1. Vuilleumier R, Miao M, Medina-Giro S, Ell CM, Flibotte S, Lian T, Kauwe G, Collins A, Ly S, Pyrowolakis G, Haghighi AP, Allan DW. Dichotomous cis-regulatory motifs mediate the maturation of the neuromuscular junction by retrograde BMP signaling. Nucleic Acids Res. 2022 Aug 27:gkac730. doi: 10.1093/nar/gkac730. Epub ahead of print. PMID: 36029115.

2. Koch M, Noonan AJC, Qiu Y, Dofher K, Kieft B, Mottahedeh S, Shastri M, Hallam SJ. The survivor strain: isolation and characterization of Phormidium yuhuli AB48, a filamentous phototactic cyanobacterium with biotechnological potential. Front Bioeng Biotechnol. 2022 Aug 15;10:932695. doi: 10.3389/fbioe.2022.932695. PMID: 36046667; PMCID: PMC9420970.

3. Skovsø S, Overby P, Memar-Zadeh J, Lee JTC, Yang JCC, Shanina I, Sidarala V, Levi-D'Ancona E, Zhu J, Soleimanpour SA, Horwitz MS, Johnson JD. Beta-cell Cre expression and reduced Ins1 gene dosage protect mice from type 1 diabetes. Endocrinology. 2022 Sep 1:bqac144. doi: 10.1210/endocr/bqac144. Epub ahead of print. PMID: 36048448.

4. Flanagan K, Li W, Greenblatt EJ, Dao Duc K. End-to-end pipeline for differential analysis of pausing in ribosome profiling data. STAR Protoc. 2022 Aug 18;3(3):101605. doi: 10.1016/j.xpro.2022.101605. PMID: 36035799; PMCID: PMC9405084.

5. Cronin SJF, Rao S, Tejada MA, Turnes BL, Licht-Mayer S, Omura T, Brenneis C, Jacobs E, Barrett L, Latremoliere A, Andrews N, Channon KM, Latini A, Arvanites AC, Davidow LS, Costigan M, Rubin LL, Penninger JM, Woolf CJ. Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer. Sci Transl Med. 2022 Aug 31;14(660):eabj1531. doi: 10.1126/scitranslmed.abj1531. Epub 2022 Aug 31. PMID: 36044597.

August 29, Pubcrawler Hits:

1. Pryzdial ELG, Leatherdale A, Conway EM. Coagulation and complement: Key innate defense participants in a seamless web. Front Immunol. 2022 Aug 9;13:918775. doi: 10.3389/fimmu.2022.918775. PMID: 36016942; PMCID: PMC9398469.

2. Hohman LS, Osborne LC. A gut-centric view of aging: Do intestinal epithelial cells contribute to age-associated microbiota changes, inflammaging, and immunosenescence? Aging Cell. 2022 Aug 24:e13700. doi: 10.1111/acel.13700. Epub ahead of print. PMID: 36000805.

August 22, Pubcrawler Hits:

1. Al Fayez N, Böttger R, Ghosh S, Nakajima Y, Chao PH, Rouhollahi E, Nguyen A, Cullis PR, Witzigmann D, Li SD. Development of a child-friendly oral drug formulation using liposomal multilamellar vesicle technology. Int J Pharm. 2022 Aug 12;625:122107. doi: 10.1016/j.ijpharm.2022.122107. Epub ahead of print. PMID: 35964828.

2. Rideout EJ, Tennessen JM. Editorial. Semin Cell Dev Biol. 2022 Aug 12:S1084-9521(22)00254-3. doi: 10.1016/j.semcdb.2022.08.003. Epub ahead of print. PMID: 35970667.

3. Li T, Sun Y, Zhang S, Xu Y, Li K, Xie C, Wang Y, Wang Y, Cao J, Wang X, Penninger JM, Kroemer G, Blomgren K, Zhu C. AIF Overexpression Aggravates Oxidative Stress in Neonatal Male Mice After Hypoxia-Ischemia Injury. Mol Neurobiol. 2022 Aug 17. doi: 10.1007/s12035-022-02987-0. Epub ahead of print. PMID: 35974295.

4. Mei Y, Yu K, Yazdani-Ahmadabadi H, Lange D, Kizhakkedathu JN. Hydrophilic Polymer-Guided Polycatecholamine Assembly and Surface Deposition. ACS Appl Mater Interfaces. 2022 Aug 17. doi: 10.1021/acsami.2c10749. Epub ahead of print. PMID: 35975924.

August 15, Pubcrawler Hits:

1. Conway EM, Mackman N, Warren RQ, Wolberg AS, Mosnier LO, Campbell RA, Gralinski LE, Rondina MT, van de Veerdonk FL, Hoffmeister KM, Griffin JH, Nugent D, Moon K, Morrissey JH. Understanding COVID-19-associated coagulopathy. Nat Rev Immunol. 2022 Aug 5:1–11. doi: 10.1038/s41577-022-00762-9. Epub ahead of print. PMID: 35931818; PMCID: PMC9362465.

2. Tadini-Buoninsegni F, Mikkelsen SA, Mogensen LS, Holm R, Molday RS, Andersen JP. Electrogenic reaction step and phospholipid translocation pathway of the mammalian P4-ATPase ATP8A2. FEBS Lett. 2022 Jul 30. doi: 10.1002/1873-3468.14459. Epub ahead of print. PMID: 35945663.

3. Sao Emani C, Richter A, Singh A, Bhatt A, Av-Gay Y. The ΔCysK2 mutant of Mycobacterium tuberculosis is sensitive to vancomycin associated with changes in cell wall phospholipid profile. Biochem Biophys Res Commun. 2022 Aug 2;624:120-126. doi: 10.1016/j.bbrc.2022.07.096. Epub ahead of print. PMID: 35940124.

4. Goswami J, MacArthur TA, Mahony C, Kizhakkedathu JN, Vappala S, Smith S, Morrissey JH, Spears GM, Bailey KR, Dong JF, Kozar RA, Hall N, Johnstone A, Park MS. DNAse Mediated Dissolution of Neutrophil Extracellular Traps (NETs) Accelerates in vitro Thrombin Generation Kinetics in Trauma Patients. Shock. 2022 Aug 9. doi: 10.1097/SHK.0000000000001972. Epub ahead of print. PMID: 35959777.

August 8, Pubcrawler Hits:

1. Conway EM, Pryzdial ELG. Complement contributions to COVID-19. Curr Opin Hematol. 2022 Sep 1;29(5):259-265. doi: 10.1097/MOH.0000000000000724. Epub 2022 Jul 11. PMID: 35852851.

2. Pereyra N, Devine DV. "How do I/we forecast tomorrows' transfusion: Blood components". Transfus Clin Biol. 2022 Jul 29:S1246-7820(22)00090-8. doi: 10.1016/j.tracli.2022.07.006. Epub ahead of print. PMID: 35914702.

3. Sugden S, Holert J, Cardenas E, Mohn WW, Stein LY. Microbiome of the freshwater sponge Ephydatia muelleri shares compositional and functional similarities with those of marine sponges. ISME J. 2022 Jul 29. doi: 10.1038/s41396-022-01296-7. Epub ahead of print. PMID: 35906397.

4. Li RC, Molday LL, Lin CC, Ren X, Fleischmann A, Molday RS, Yau KW. Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2121225119. doi: 10.1073/pnas.2121225119. Epub 2022 Aug 1. PMID: 35914143.

5. Rayani K, Hantz ER, Haji-Ghassemi O, Li AY, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. The effect of Mg2+ on Ca2+ binding to cardiac troponin C in hypertrophic cardiomyopathy associated TNNC1 variants. FEBS J. 2022 Jul 15. doi: 10.1111/febs.16578. Epub ahead of print. PMID: 35838319.

6. Sinnberg T, Lichtensteiger C, Hasan Ali O, Pop OT, Jochum AK, Risch L, Brugger SD, Velic A, Bomze D, Kohler P, Vernazza P, Albrich WC, Kahlert CR, Abdou MT, Wyss N, Hofmeister K, Niessner H, Zinner C, Gilardi M, Tzankov A, Röcken M, Dulovic A, Mairpady Shambat S, Ruetalo N, Buehler PK, Scheier TC, Jochum W, Kern L, Henz S, Schneider T, Kuster GM, Lampart M, Siegemund M, Bingisser R, Schindler M, Schneiderhan-Marra N, Kalbacher H, McCoy KD, Spengler W, Brutsche MH, Macek B, Twerenbold R, Penninger JM, Matter MS, Flatz L. Pulmonary Surfactant Proteins are Inhibited by IgA Autoantibodies in Severe COVID-19. Am J Respir Crit Care Med. 2022 Aug 4. doi: 10.1164/rccm.202201-0011OC. Epub ahead of print. PMID: 35926164.

7. Fell CW, Hagelkruys A, Cicvaric A, Horrer M, Liu L, Li JSS, Stadlmann J, Polyansky AA, Mereiter S, Tejada MA, Kokotović T, Achuta VS, Scaramuzza A, Twyman KA, Morrow MM, Juusola J, Yan H, Wang J, Burmeister M, Choudhury B, Andersen TL, Wirnsberger G, Holmskov U, Perrimon N, Žagrović B, Monje FJ, Moeller JB, Penninger JM, Nagy V. FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder. EMBO Mol Med. 2022 Aug 2:e15829. doi: 10.15252/emmm.202215829. Epub ahead of print. PMID: 35916241.

8. Lee JH, Park ES, Choi JR, Matthews K, Lam AV, Deng X, Duffy SP, Ma H. See-N-Seq: RNA sequencing of target single cells identified by microscopy via micropatterning of hydrogel porosity. Commun Biol. 2022 Jul 30;5(1):768. doi: 10.1038/s42003-022-03703-3. PMID: 35908100; PMCID: PMC9338959.

August 1, Pubcrawler Hits:

1. Chu X, Wang X, Cheung LS, Feng X, Ang P Jr, Lee SY, Crowe SA, Luo H. Coastal Transient Niches Shape the Microdiversity Pattern of a Bacterioplankton Population with Reduced Genomes. mBio. 2022 Jul 26:e0057122. doi: 10.1128/mbio.00571-22. Epub ahead of print. PMID: 35880883.

2. Márquez AC, Croft C, Shanina I, Horwitz MS. Influence of Type I Interferons in Gammaherpesvirus-68 and Its Influence on EAE Enhancement. Front Immunol. 2022 Jul 7;13:858583. doi: 10.3389/fimmu.2022.858583. PMID: 35874728; PMCID: PMC9301468.

3. Ludwig DS, Apovian CM, Aronne LJ, Astrup A, Cantley LC, Ebbeling CB, Heymsfield SB, Johnson JD, King JC, Krauss RM, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS Jr, Friedman MI. Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models. Eur J Clin Nutr. 2022 Jul 28. doi: 10.1038/s41430-022-01179-2. Epub ahead of print. PMID: 35896818.

4. Philippe TJ, Bao L, Koblanski ME, Viau V. Sex differences in serotonin 5-HT 1A receptor responses to repeated restraint stress in adult male and female rats. Int J Neuropsychopharmacol. 2022 Jul 29:pyac046. doi: 10.1093/ijnp/pyac046. Epub ahead of print. PMID: 35904324.

5. Baker JA, Breit KR, Bodnar TS, Weinberg J, Thomas JD. Choline Supplementation Modifies the Effects of Developmental Alcohol Exposure on Immune Responses in Adult Rats. Nutrients. 2022 Jul 13;14(14):2868. doi: 10.3390/nu14142868. PMID: 35889826; PMCID: PMC9316525.

6. Tsui CKM, Sorrentino F, Narula G, Mendoza-Losana A, Del Rio RG, Herrán EP, Lopez A, Bojang A, Zheng X, Remuiñán-Blanco MJ, Av-Gay Y. Hit Compounds and Associated Targets in Intracellular Mycobacterium tuberculosis. Molecules. 2022 Jul 12;27(14):4446. doi: 10.3390/molecules27144446. PMID: 35889319; PMCID: PMC9324642.

7. Minato T, Yamaguchi T, Hoshizaki M, Nirasawa S, An J, Takahashi S, Penninger JM, Imai Y, Kuba K. ACE2-like enzyme B38-CAP suppresses abdominal sepsis and severe acute lung injury. PLoS One. 2022 Jul 22;17(7):e0270920. doi: 10.1371/journal.pone.0270920. PMID: 35867642; PMCID: PMC9307200.

8. Basharat Z, Moon KM, Foster LJ, Yasmin A. Impact of Azo Dyes and Ibuprofen on the Proteome of Serratia nematodiphila sp. MB307. Curr Protein Pept Sci. 2022 Jul 27. doi: 10.2174/1389203723666220727142630. Epub ahead of print. PMID: 35894467.

July 25, Pubcrawler Hits:

1. Islamzada E, Matthews K, Lamoureux ES, Duffy SP, Scott MD, Ma H. Degradation of red blood cell deformability during cold storage in blood bags. EJHaem. 2021 Nov 24;3(1):63-71. doi: 10.1002/jha2.343. PMID: 35846223; PMCID: PMC9176030.

2. Vasyliuk D, Felt J, Zhong ED, Berger B, Davis JH, Yip CK. Conformational landscape of the yeast SAGA complex as revealed by cryo-EM. Sci Rep. 2022 Jul 19;12(1):12306. doi: 10.1038/s41598-022-16391-0. PMID: 35853968; PMCID: PMC9296673.

July 18, Pubcrawler Hits:

1. Wild AR, Hogg PW, Flibotte S, Nasseri G, Hollman R, Abazari D, Haas K, Bamji SX. Exploring the expression patterns of palmitoylating and de-palmitoylating enzymes in the mouse brain using the curated RNA-seq database BrainPalmSeq. Elife. 2022 Jul 12;11:e75804. doi: 10.7554/eLife.75804. Epub ahead of print. PMID: 35819139.

2. Ou YF, Dong HP, McIlroy SJ, Crowe SA, Hallam SJ, Han P, Kallmeyer J, Simister RL, Vuillemin A, Leu AO, Liu Z, Zheng YL, Sun QL, Liu M, Tyson GW, Hou LJ. Expanding the phylogenetic distribution of cytochrome b-containing methanogenic archaea sheds light on the evolution of methanogenesis. ISME J. 2022 Jul 9. doi: 10.1038/s41396-022-01281-0. Epub ahead of print. PMID: 35810262.

3. Castillo G, Vesnaver E, Gibson E, Butler-Foster T, Goldman M, Hill NE, Rosser A, Lapierre D, Rubini KA, MacDonagh R, Miguel G, Palumbo A, MacPherson P, Randall T, Osbourne-Sorrell W, O'Brien SF, Bridel W, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J. Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men. Transfusion. 2022 Jul 14. doi: 10.1111/trf.17000. Epub ahead of print. PMID: 35834537.

4. Hohman LS, Osborne LC. Eo, what are we doing here? Immunity. 2022 Jul 12;55(7):1148-1150. doi: 10.1016/j.immuni.2022.06.015. PMID: 35830822.

5. Tropini C. A bacterial record collection. Cell Host Microbe. 2022 Jul 13;30(7):905-907. doi: 10.1016/j.chom.2022.06.002. PMID: 35834961.

6. Raglow Z, McKenna MK, Bonifant CL, Wang W, Pasca di Magliano M, Stadlmann J, Penninger JM, Cummings RD, Brenner MK, Markovitz DM. Targeting Glycans for CAR Therapy: the Advent of Sweet CARs. Mol Ther. 2022 Jul 11:S1525-0016(22)00427-0. doi: 10.1016/j.ymthe.2022.07.006. Epub ahead of print. PMID: 35821636.

7. Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Development of an aerosol intervention for COVID-19 disease: Tolerability of soluble ACE2 (APN01) administered via nebulizer. PLoS One. 2022 Jul 11;17(7):e0271066. doi: 10.1371/journal.pone.0271066. PMID: 35816490; PMCID: PMC9273060.

July 11, Pubcrawler Hits:

1. Quick J, Santos ND, Cheng MHY, Chander N, Brimacombe CA, Kulkarni J, van der Meel R, Tam YYC, Witzigmann D, Cullis PR. Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy. J Control Release. 2022 Jul 7;349:174-183. doi: 10.1016/j.jconrel.2022.06.051. Epub ahead of print. PMID: 35780952.

2. Mouat IC, Goldberg E, Horwitz MS. Age-associated B cells in autoimmune diseases. Cell Mol Life Sci. 2022 Jul 7;79(8):402. doi: 10.1007/s00018-022-04433-9. PMID: 35798993; PMCID: PMC9263041.

3. Pancaroglu R, Van Petegem F. It takes two to tango: Rycals and ATP snuggle up to bind ryanodine receptors. Structure. 2022 Jul 7;30(7):919-921. doi: 10.1016/j.str.2022.05.022. PMID: 35803239.

4. Pop S, Urtatiz O, Van Raamsdonk CD. Isolation of tdTomato Expressing Inter-follicular Epidermal Melanocytes or Keratinocytes from Mouse Tail Skin. Bio Protoc. 2022 Apr 20;12(8):e4398. doi: 10.21769/BioProtoc.4398. PMID: 35800096; PMCID: PMC9081482.

5. Monteil V, Eaton B, Postnikova E, Murphy M, Braunsfeld B, Crozier I, Kricek F, Niederhöfer J, Schwarzböck A, Breid H, Devignot S, Klingström J, Thålin C, Kellner MJ, Christ W, Havervall S, Mereiter S, Knapp S, Sanchez Jimenez A, Bugajska-Schretter A, Dohnal A, Ruf C, Gugenberger R, Hagelkruys A, Montserrat N, Kozieradzki I, Hasan Ali O, Stadlmann J, Holbrook MR, Schmaljohn C, Oostenbrink C, Shoemaker RH, Mirazimi A, Wirnsberger G, Penninger JM. Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants. EMBO Mol Med. 2022 Jul 4:e15230. doi: 10.15252/emmm.202115230. Epub ahead of print. PMID: 35781796.

6. Geissmann Q, Abram PK, Wu D, Haney CH, Carrillo J. Sticky Pi is a high-frequency smart trap that enables the study of insect circadian activity under natural conditions. PLoS Biol. 2022 Jul 7;20(7):e3001689. doi: 10.1371/journal.pbio.3001689. PMID: 35797311; PMCID: PMC9262196.

July 4, Pubcrawler Hits:

1. Gao P, Wei Y, Tai SSC, Halebeedu Prakash P, Iu HTV, Li Y, Yam HCB, Chen JHK, Ho PL, Davies J, Kao RYT. Antivirulence Agent as an Adjuvant of β-Lactam Antibiotics in Treating Staphylococcal Infections. Antibiotics (Basel). 2022 Jun 17;11(6):819. doi: 10.3390/antibiotics11060819. PMID: 35740225; PMCID: PMC9219823.

2. Zhao HQ, Serrano K, Culibrk B, Chen Z, Devine DV. Cold-stored platelets are effective in an in vitro model of massive transfusion protocol assessed by rotational thromboelastometry. Transfusion. 2022 Jun 24. doi: 10.1111/trf.16974. Epub ahead of print. PMID: 35748809.

3. Schubert P, Culibrk B, Bhakta V, Closas T, Sheffield WP, Devine DV, McTaggart K. Minimal impact of anticoagulant on in vitro whole blood quality throughout a 35-day cold-storage regardless of leukoreduction timing. Transfusion. 2022 Jun 24. doi: 10.1111/trf.16977. Epub ahead of print. PMID: 35748674.

4. Willegems K, Eldstrom J, Kyriakis E, Ataei F, Sahakyan H, Dou Y, Russo S, Van Petegem F, Fedida D. Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nat Commun. 2022 Jun 29;13(1):3760. doi: 10.1038/s41467-022-31526-7. PMID: 35768468; PMCID: PMC9243137.

5. Martin BJE, Howe LJ. Reply to: Pitfalls in using phenanthroline to study the causal relationship between promoter nucleosome acetylation and transcription. Nat Commun. 2022 Jun 29;13(1):3725. doi: 10.1038/s41467-022-30351-2. PMID: 35768425; PMCID: PMC9243053.

6. Foster LJ. The adult mouse proteome. Nat Methods. 2022 Jun 23. doi: 10.1038/s41592-022-01546-8. Epub ahead of print. PMID: 35739311.

7. McDowell SAT, Stanley M, Gordon MD. A molecular mechanism for high salt taste in Drosophila. Curr Biol. 2022 Jun 24:S0960-9822(22)00924-1. doi: 10.1016/j.cub.2022.06.012. Epub ahead of print. PMID: 35772408.

June 27, Pubcrawler Hits:

1. Basha G, Cottle AG, Pretheeban T, Chan KY, Witzigmann D, Young RN, Rossi FM, Cullis PR. Lipid Nanoparticle Mediated Silencing of Osteogenic Suppressor GNAS Leads to Osteogenic Differentiation of Mesenchymal Stem Cells In Vivo. Mol Ther. 2022 Jun 22:S1525-0016(22)00372-0. doi: 10.1016/j.ymthe.2022.06.012. Epub ahead of print. PMID: 35733339.

2. Zhigaltsev IV, Tam YYC, Kulkarni JA, Cullis PR. Synthesis and Characterization of Hybrid Lipid Nanoparticles Containing Gold Nanoparticles and a Weak Base Drug. Langmuir. 2022 Jun 16. doi: 10.1021/acs.langmuir.2c01221. Epub ahead of print. PMID: 35708310.

3. Brown JAR, Cui JH, Ling MYM, Gao EXC, Howe LJ, Teves SS. 43rd International Asilomar Chromatin, Chromosomes, and Epigenetics Conference. Biochem Cell Biol. 2022 Jun 21. doi: 10.1139/bcb-2022-0132. Epub ahead of print. PMID: 35728263.

4. Brind'Amour J, Lorincz MC. Profiling Histone Methylation in Low Numbers of Cells. Methods Mol Biol. 2022;2529:229-251. doi: 10.1007/978-1-0716-2481-4_11. PMID: 35733018.

5. Mothersole RG, Kolesnikov M, Chan ACK, Oduro E, Murphy MEP, Wolthers KR. Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry. 2022 Jun 22. doi: 10.1021/acs.biochem.2c00197. Epub ahead of print. PMID: 35732022.

6. Bell EM, Graves ML, Dean PM, Goodman TO, Roskelley CD. Modeling Collective Invasion and Single-Cell Mesenchymal Invasion in Three-Dimensional Matrigel-Collagen I Cultures. Methods Mol Biol. 2022;2508:79-99. doi: 10.1007/978-1-0716-2376-3_8. PMID: 35737235.

7. Nourbakhsh H, Adams A, Raverty S, Vogl AW, Haulena M, Skoretz SA. Microscopic Anatomy of the Upper Aerodigestive Tract in Harbour Seals (Phoca vitulina): Functional Adaptations to Swallowing. Anat Rec (Hoboken). 2022 Jun 19. doi: 10.1002/ar.25025. Epub ahead of print. PMID: 35719006.

8. Barvalia M, Harder KW. An End-to-End Workflow for Interrogating Tumor-Infiltrating Myeloid Cells Using Mass Cytometry. Methods Mol Biol. 2022;2508:147-168. doi: 10.1007/978-1-0716-2376-3_12. PMID: 35737239.

9. Flanagan K, Baradaran-Heravi A, Yin Q, Dao Duc K, Spradling AC, Greenblatt EJ. FMRP-dependent production of large dosage-sensitive proteins is highly conserved. Genetics. 2022 Jun 22:iyac094. doi: 10.1093/genetics/iyac094. Epub ahead of print. PMID: 35731217.

June 20, Pubcrawler Hits:

1. Grist SM, Bennewith KL, Cheung KC. Oxygen Measurement in Microdevices. Annu Rev Anal Chem (Palo Alto Calif). 2022 Jun 13;15(1):221-246. doi: 10.1146/annurev-anchem-061020-111458. PMID: 35696522.

June 13, Pubcrawler Hits:

1. Dhume SH, Connor SA, Mills F, Tari PK, Au-Yeung SHM, Karimi B, Oku S, Roppongi RT, Kawabe H, Bamji SX, Wang YT, Brose N, Jackson MF, Craig AM, Siddiqui TJ. Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits. Elife. 2022 Jun 6;11:e64742. doi: 10.7554/eLife.64742. PMID: 35662394; PMCID: PMC9170246.

2. Cikes D, Atanes P, Cronin SJF, Hagelkrüys A, Huang GC, Persaud SJ, Penninger JM. Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide. Sci Rep. 2022 Jun 7;12(1):9383. doi: 10.1038/s41598-022-13060-0. PMID: 35672347; PMCID: PMC9174263.

3. Rath M, Schwefel K, Malinverno M, Skowronek D, Leopoldi A, Pilz RA, Biedenweg D, Bekeschus S, Penninger JM, Dejana E, Felbor U. Contact-dependent signaling triggers tumor-like proliferation of CCM3 knockout endothelial cells in co-culture with wild-type cells. Cell Mol Life Sci. 2022 Jun 4;79(6):340. doi: 10.1007/s00018-022-04355-6. PMID: 35661927; PMCID: PMC9166869.

June 6, Pubcrawler Hits:

1. Rittberg R, Abraham N, Laskin J, Ho C. Hyper-Sensitive? Targeted Therapy With a Primed Immune System. J Thorac Oncol. 2022 Jun;17(6):734-736. doi: 10.1016/j.jtho.2022.03.003. PMID: 35623671.

2. Shimizu T, Aritoshi T, Beatty JT, Masuda T. Persulfide-Responsive Transcription Factor SqrR Regulates Gene Transfer and Biofilm Formation via the Metabolic Modulation of Cyclic di-GMP in Rhodobacter capsulatus. Microorganisms. 2022 Apr 26;10(5):908. doi: 10.3390/microorganisms10050908. PMID: 35630353; PMCID: PMC9143464.

3. Rankine-Wilson L, Rens C, Sahile HA, Av-Gay Y. Mycobacterium tuberculosis Infection of THP-1 Cells: A Model for High Content Analysis of Intracellular Growth and Drug Susceptibility. Methods Mol Biol. 2022;2427:73-82. doi: 10.1007/978-1-0716-1971-1_7. PMID: 35619026.

4. John L, Vernersson C, Kwon H, Elling U, Penninger JM, Mirazimi A. Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study. Pathogens. 2022 May 22;11(5):602. doi: 10.3390/pathogens11050602. PMID: 35631123; PMCID: PMC9144988.

5. Batlle D, Monteil V, Garreta E, Hassler L, Wysocki J, Chandar V, Schwartz RE, Mirazimi A, Montserrat N, Bader M, Penninger JM. Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity. Cell. 2022 May 26;185(11):1837-1839. doi: 10.1016/j.cell.2022.05.004. PMID: 35623327; PMCID: PMC9134488.

6. Yazdani-Ahmadabadi H, Felix DF, Yu K, Yeh HH, Luo HD, Khoddami S, Takeuchi LE, Alzahrani A, Abbina S, Mei Y, Fazli L, Grecov D, Lange D, Kizhakkedathu JN. Durable Surfaces from Film-Forming Silver Assemblies for Long-Term Zero Bacterial Adhesion without Toxicity. ACS Cent Sci. 2022 May 25;8(5):546-561. doi: 10.1021/acscentsci.1c01556. Epub 2022 Apr 27. PMID: 35647287; PMCID: PMC9136974.

May 30, Pubcrawler Hits:

1. Sheikh A, Lu J, Melese E, Seo JH, Abraham N. IL-7 induces type 2 cytokine response in lung ILC2s and regulates GATA3 and CD25 expression. J Leukoc Biol. 2022 May 23. doi: 10.1002/JLB.3AB1220-819RRR. Epub ahead of print. PMID: 35603486.

2. Canals Hernaez D, Hughes MR, Li Y, Mainero Rocca I, Dean P, Brassard J, Bell EM, Samudio I, Mes-Masson AM, Narimatsu Y, Clausen H, Blixt O, Roskelley CD, McNagny KM. Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models. Front Oncol. 2022 May 4;12:856424. doi: 10.3389/fonc.2022.856424. PMID: 35600398; PMCID: PMC9115113.

3. Young JW, Wason IS, Zhao Z, Kim S, Aoki H, Phanse S, Rattray DG, Foster LJ, Babu M, Duong van Hoa F. Development of a Method Combining Peptidiscs and Proteomics to Identify, Stabilize, and Purify a Detergent-Sensitive Membrane Protein Assembly. J Proteome Res. 2022 May 26. doi: 10.1021/acs.jproteome.2c00129. Epub ahead of print. PMID: 35616533.

4. Houfani AA, Foster LJ. Review of the Real and Sometimes Hidden Costs in Proteomics Experimental Workflows. Methods Mol Biol. 2022;2456:1-14. doi: 10.1007/978-1-0716-2124-0_1. PMID: 35612731.

5. Lu-Culligan A, Tabachnikova A, Pérez-Then E, Tokuyama M, Lee HJ, Lucas C, Silva Monteiro V, Miric M, Brache V, Cochon L, Muenker MC, Mohanty S, Huang J, Kang I, Dela Cruz C, Farhadian S, Campbell M, Yildirim I, Shaw AC, Ma S, Vermund SH, Ko AI, Omer SB, Iwasaki A. No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination. PLoS Biol. 2022 May 24;20(5):e3001506. doi: 10.1371/journal.pbio.3001506. PMID: 35609110; PMCID: PMC9129011.

May 23, Pubcrawler Hits:

1. Cheng MHY, Brimacombe CA, Verbeke R, Cullis PR. Exciting Times for Lipid Nanoparticles: How Canadian Discoveries Are Enabling Gene Therapies. Mol Pharm. 2022 May 18. doi: 10.1021/acs.molpharmaceut.2c00365. Epub ahead of print. PMID: 35583489.

2. Garreta E, Prado P, Stanifer ML, Monteil V, Marco A, Ullate-Agote A, Moya-Rull D, Vilas-Zornoza A, Tarantino C, Romero JP, Jonsson G, Oria R, Leopoldi A, Hagelkruys A, Gallo M, González F, Domingo-Pedrol P, Gavaldà A, Del Pozo CH, Hasan Ali O, Ventura-Aguiar P, Campistol JM, Prosper F, Mirazimi A, Boulant S, Penninger JM, Montserrat N. A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells. Cell Metab. 2022 May 10:S1550-4131(22)00136-X. doi: 10.1016/j.cmet.2022.04.009. Epub ahead of print. PMID: 35561674; PMCID: PMC9097013.

3. Lee R, Witherspoon L, Robinson M, Lee JH, Duffy SP, Flannigan R, Ma H. Automated rare sperm identification from low-magnification microscopy images of dissociated microsurgical testicular sperm extraction samples using deep learning. Fertil Steril. 2022 May 10:S0015-0282(22)00195-9. doi: 10.1016/j.fertnstert.2022.03.011. Epub ahead of print. PMID: 35562203.

May 16, Pubcrawler Hits:

1. Pawar SV, Hallam SJ, Yadav VG. Metagenomic discovery of a novel transaminase for valorization of monoaromatic compounds. RSC Adv. 2018 Jun 20;8(40):22490-22497. doi: 10.1039/c8ra02764a. PMID: 35539725; PMCID: PMC9081488.

2. Zuo M, Fettig NM, Bernier LP, Pössnecker E, Spring S, Pu A, Ma XI, Lee DS, Ward LA, Sharma A, Kuhle J, Sled JG, Pröbstel AK, MacVicar BA, Osborne LC, Gommerman JL, Ramaglia V. Age-dependent grey matter demyelination is associated with leptomeningeal neutrophil accumulation. JCI Insight. 2022 May 10:e158144. doi: 10.1172/jci.insight.158144. Epub ahead of print. PMID: 35536649.

3. Holguin-Cruz JA, Foster LJ, Gsponer J. Where protein structure and cell diversity meet. Trends Cell Biol. 2022 May 7:S0962-8924(22)00092-7. doi: 10.1016/j.tcb.2022.04.004. Epub ahead of print. PMID: 35537902.

May 9, Pubcrawler Hits:

1. Levy-Booth DJ, Navas LE, Fetherolf MM, Liu LY, Dalhuisen T, Renneckar S, Eltis LD, Mohn WW. Discovery of lignin-transforming bacteria and enzymes in thermophilic environments using stable isotope probing. ISME J. 2022 May 2. doi: 10.1038/s41396-022-01241-8. Epub ahead of print. PMID: 35501417.

2. Abbina S, La CC, Vappala S, Kalathottukaren MT, Abbasi U, Gill A, Smith SA, Haynes CA, Morrissey JH, Kizhakkedathu JN. Influence of Steric Shield on Biocompatibility and Antithrombotic Activity of Dendritic Polyphosphate Inhibitor. Mol Pharm. 2022 May 2. doi: 10.1021/acs.molpharmaceut.1c00934. Epub ahead of print. PMID: 35500201.

May 2, Pubcrawler Hits:

1. Melese ES, Franks E, Cederberg RA, Harbourne BT, Shi R, Wadsworth BJ, Collier JL, Halvorsen EC, Johnson F, Luu J, Oh MH, Lam V, Krystal G, Hoover SB, Raffeld M, Simpson RM, Unni AM, Lam WL, Lam S, Abraham N, Bennewith KL, Lockwood WW. CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development. Oncoimmunology. 2021 Dec 30;11(1):2010905. doi: 10.1080/2162402X.2021.2010905. PMID: 35481284; PMCID: PMC9038050.

2. Ask A, Eltringham-Smith L, Bhakta V, Donkor DA, Pryzdial ELG, Sheffield WP. Spotlight on animal models of acute traumatic coagulopathy: An update. Transfus Apher Sci. 2022 Mar 10:103412. doi: 10.1016/j.transci.2022.103412. Epub ahead of print. PMID: 35283031.

3. Feresten AH, Bhat JM, Yu AJ, Zapf R, Safi H, Au V, Flibotte S, Doell C, Moerman DG, Hawkins N, Rankin CH, Hutter H. ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans. Genetics. 2022 Apr 4;220(4):iyac024. doi: 10.1093/genetics/iyac024. PMID: 35143653; PMCID: PMC8982044.

Apr 25, Pubcrawler Hits:

1. Ramzy A, Edeer N, Baker RK, O'Dwyer S, Mojibian M, Verchere CB, Kieffer TJ. Insulin null ß-cells have a prohormone processing defect that is not reversed by AAV rescue of proinsulin expression. Endocrinology. 2022 Apr 18:bqac051. doi: 10.1210/endocr/bqac051. Epub ahead of print. PMID: 35435956.

2. Abdelilah-Seyfried S, Iruela-Arispe ML, Penninger JM, Tournier-Lasserve E, Vikkula M, Cleaver O. Recalibrating vascular malformations and mechanotransduction by pharmacological intervention. J Clin Invest. 2022 Apr 15;132(8):e160227. doi: 10.1172/JCI160227. PMID: 35426368; PMCID: PMC9012280.

Apr 18, Pubcrawler Hits:

1. Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ. Adult T-cells impair neonatal cardiac regeneration. Eur Heart J. 2022 Apr 13:ehac188. doi: 10.1093/eurheartj/ehac153. Epub ahead of print. PMID: 35417553.

Apr 11, Pubcrawler Hits:

1. Vardaki MZ, Georg Schulze H, Serrano K, Blades MW, Devine DV, F B Turner R. Assessing the quality of stored red blood cells using handheld Spatially Offset Raman spectroscopy with multisource correlation analysis. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Apr 1;276:121220. doi: 10.1016/j.saa.2022.121220. Epub ahead of print. PMID: 35395462.

Apr 4, Pubcrawler Hits:

1. Navas LE, Zahn M, Bajwa H, Grigg JC, Wolf ME, Chan ACK, Murphy MEP, McGeehan JE, Eltis LD. Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. J Biol Chem. 2022 Mar 25:101871. doi: 10.1016/j.jbc.2022.101871. Epub ahead of print. PMID: 35346686.

2. Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic. Nature. 2022 Mar 28. doi: 10.1038/s41586-022-04661-w. Epub ahead of print. PMID: 35344983.

3. Fedoretz-Maxwell BP, Shin CH, MacNeil GA, Worrall LJ, Park R, Strynadka NCJ, Walsby CJ, Warren JJ. The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorg Chem. 2022 Mar 29. doi: 10.1021/acs.inorgchem.2c00030. Epub ahead of print. PMID: 35347989.

Mar 28, Pubcrawler Hits:

1. Budzyński MA, Teves SS. System reset: topoisomerase 1 clears mitotic DNA for transcriptional memory. Trends Biochem Sci. 2022 Mar 17:S0968-0004(22)00064-0. doi: 10.1016/j.tibs.2022.03.005. Epub ahead of print. PMID: 35307259.

Mar 21, Pubcrawler Hits:

1. Tsai MS, Wang LC, Wu HL, Tzeng SF, Conway EM, Hsu SM, Chen SH. Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses. J Neuroinflammation. 2022 Mar 11;19(1):66. doi: 10.1186/s12974-022-02426-w. PMID: 35277184; PMCID: PMC8915510.

2. Labouta HI, Langer R, Cullis PR, Merkel OM, Prausnitz MR, Gomaa Y, Nogueira SS, Kumeria T. Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective. Drug Deliv Transl Res. 2022 Mar 15:1–8. doi: 10.1007/s13346-022-01146-1. Epub ahead of print. PMID: 35290656; PMCID: PMC8923087.

3. Van De Ven CJC, Laurenzi L, Arnold AC, Hallam SJ, Mayer KU. The nature of gas production patterns associated with methanol degradation in natural aquifer sediments: A microcosm study. J Contam Hydrol. 2022 Mar 8;247:103988. doi: 10.1016/j.jconhyd.2022.103988. Epub ahead of print. PMID: 35303484.

4. Mouat IC, Horwitz MS. Age-associated B cells in viral infection. PLoS Pathog. 2022 Mar 17;18(3):e1010297. doi: 10.1371/journal.ppat.1010297. PMID: 35298565; PMCID: PMC8929649.

5. Patil S, Dou Y, Kopp JL. Cell Type of Pancreatic Ductal Adenocarcinoma Origin: Implications for Prognosis and Clinical Outcomes. Visc Med. 2022 Feb;38(1):4-10. doi: 10.1159/000520946. Epub 2021 Dec 27. PMID: 35295896; PMCID: PMC8874250.

6. Qin J, Zhang J, Lin L, Haji-Ghassemi O, Lin Z, Woycechowsky KJ, Van Petegem F, Zhang Y, Yuchi Z. Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy. Elife. 2022 Mar 17;11:e75346. doi: 10.7554/eLife.75346. Epub ahead of print. PMID: 35297759.

7. Clephane K, O'Loughlin JI, Bodnar TS, Wilson MC, Stariha JT, Craig AN, Weinberg J, Brotto LA, Lorenz TK. Lack of Evidence for a Relationship Between Salivary CRP and Women's Sexual Desire: An Investigation Across Clinical and Healthy Samples. J Sex Med. 2022 Mar 13:S1743-6095(22)00583-5. doi: 10.1016/j.jsxm.2022.02.007. Epub ahead of print. PMID: 35296386.

8. Jayewickreme R, Mao T, Philbrick W, Kong Y, Treger RS, Lu P, Rakib T, Dong H, Dang-Lawson M, Guild WA, Lau TJ, Iwasaki A, Tokuyama M. Endogenous Retroviruses Provide Protection Against Vaginal HSV-2 Disease. Front Immunol. 2022 Jan 4;12:758721. doi: 10.3389/fimmu.2021.758721. PMID: 35058919; PMCID: PMC8764156.

Mar 14, Pubcrawler Hits:

1. Al-Riyami AZ, Burnouf T, Wood EM, Devine DV, Oreh A, Apelseth TO, Goel R, Bloch EM, van Den Berg K, Getshen M, Louw V, Ang AL, Lee CK, Rahimi-Levene N, Stramer SL, Vassallo R, Schulze TJ, Patidar GK, Pandey HC, Dubey R, Badawi M, Hindawi S, Meshi A, Matsushita T, Sorrentino E, Grubovic Rastvorceva RM, Bazin R, Vermeulen M, Nahirniak S, Tsang HC, Vrielink H, Triyono T, Addas-Carvalho M, Hećimović A, Torres OW, Mutindu SM, Bengtsson J, Dominguez D, Sayedahmed A, Hanisa Musa R, Gautam B, Herczenik E, So-Osman C; ISBT COVID-19 Convalescent Plasma Working Group. International Society of Blood Transfusion survey of experiences of blood banks and transfusion services during the COVID-19 pandemic. Vox Sang. 2022 Mar 8. doi: 10.1111/vox.13256. Epub ahead of print. PMID: 35262978.

2. Kieffer TJ. I. Progress Towards a Stem Cell Based Therapy for Diabetes. J Stem Cells Regen Med. 2021 Dec 30;17(2):61. doi: 10.46582/jsrm.1702010. PMID: 35250203; PMCID: PMC8866802.

3. Matthews K, Lamoureux ES, Myrand-Lapierre ME, Duffy SP, Ma H. Technologies for measuring red blood cell deformability. Lab Chip. 2022 Mar 10. doi: 10.1039/d1lc01058a. Epub ahead of print. PMID: 35266475.

Mar 7, Pubcrawler Hits:

1. Ng L, Li YX, Van Petegem F, Accili EA. Altered cyclic nucleotide-binding and pore opening in a diseased human HCN4 channel. Biophys J. 2022 Feb 24:S0006-3495(22)00184-9. doi: 10.1016/j.bpj.2022.02.035. Epub ahead of print. PMID: 35219649.

2. Xia B, Zhu R, Zhang H, Chen B, Liu Y, Dai X, Ye Z, Zhao D, Mo F, Gao S, Wang XD, Bromme D, Wang L, Wang X, Zhang D. Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice. Oxid Med Cell Longev. 2022 Feb 17;2022:3697067. doi: 10.1155/2022/3697067. PMID: 35222796; PMCID: PMC8872668.

3. Pattipeiluhu R, Arias-Alpizar G, Basha G, Chan KYT, Bussmann J, Sharp TH, Moradi MA, Sommerdijk N, Harris EN, Cullis PR, Kros A, Witzigmann D, Campbell F. Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System. Adv Mater. 2022 Feb 25:e2201095. doi: 10.1002/adma.202201095. Epub ahead of print. PMID: 35218106.

4. Yang ZF, Panwar P, McFarlane CR, Tuinte WE, Campiglio M, Van Petegem F. Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2120416119. doi: 10.1073/pnas.2120416119. Epub 2022 Mar 1. PMID: 35238659.

5. Omachi K, Kai H, Roberge M, Miner JH. NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough. iScience. 2022 Feb 8;25(3):103891. doi: 10.1016/j.isci.2022.103891. PMID: 35243249; PMCID: PMC8866893.

6. Tocheva EI. A picture is worth a thousand words: Direct in vivo visualization of the bacterial chromosome segregation protein, PopZ. J Mol Biol. 2022 Mar 1:167521. doi: 10.1016/j.jmb.2022.167521. Epub ahead of print. PMID: 35245499.

7. King DT, Serrano-Negrón JE, Zhu Y, Moore CL, Shoulders MD, Foster LJ, Vocadlo DJ. Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome. J Am Chem Soc. 2022 Mar 1. doi: 10.1021/jacs.1c10621. Epub ahead of print. PMID: 35230102.

Feb 28, Pubcrawler Hits:

1. Hadjesfandiari N, Serrano K, Levin E, Johal P, Feenstra S, Shih AW, Devine DV. Effect of modern infusion pumps on RBC quality. Transfusion. 2022 Feb 25. doi: 10.1111/trf.16833. Epub ahead of print. PMID: 35213738.

2. Zhang AMY, Chu KH, Daly BF, Ruiter T, Dou Y, Yang JCC, de Winter TJJ, Chhuor J, Wang S, Flibotte S, Zhao YB, Hu X, Li H, Rideout EJ, Schaeffer DF, Johnson JD, Kopp JL. Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics. Cancer Metab. 2022 Feb 21;10(1):5. doi: 10.1186/s40170-022-00282-z. PMID: 35189981; PMCID: PMC8862319.

3. Pelosi C, Constantinescu I, Son HH, Tinè MR, Kizhakkedathu JN, Wurm FR. Blood Compatibility of Hydrophilic Polyphosphoesters. ACS Appl Bio Mater. 2022 Feb 24. doi: 10.1021/acsabm.1c01210. Epub ahead of print. PMID: 35201742.

4. Millington JW, Biswas P, Chao C, Xia YH, Wat LW, Brownrigg GP, Sun Z, Basner-Collins PJ, Geltink RIK, Rideout EJ. A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms. Development. 2022 Feb 23:dev.200491. doi: 10.1242/dev.200491. Epub ahead of print. PMID: 35195254.

5. Bodnar TS, Mak DY, Hill LA, Ellis L, Yu W, Weinberg J. Modulatory role of prenatal alcohol exposure and adolescent stress on the response to arthritis challenge in adult female rats. EBioMedicine. 2022 Feb 17;77:103876. doi: 10.1016/j.ebiom.2022.103876. Epub ahead of print. PMID: 35183867.

6. Humbert PO, Pryjda TZ, Pranjic B, Farrell A, Fujikura K, de Matos Simoes R, Karim R, Kozieradzki I, Cronin SJF, Neely GG, Meyer TF, Hagelkruys A, Richardson HE, Penninger JM. TSPAN6 is a suppressor of Ras-driven cancer. Oncogene. 2022 Feb 19. doi: 10.1038/s41388-022-02223-y. Epub ahead of print. Erratum in: Oncogene. 2022 Mar 15;: PMID: 35184157.

Feb 21, Pubcrawler Hits:

1. Zhao H, Devine DV. The Missing Pieces to the Cold-Stored Platelet Puzzle. Int J Mol Sci. 2022 Jan 20;23(3):1100. doi: 10.3390/ijms23031100. PMID: 35163024; PMCID: PMC8835703.

2. Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M. Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs. Sci Transl Med. 2022 Feb 16;14(632):eabm7190. doi: 10.1126/scitranslmed.abm7190. Epub 2022 Feb 16. PMID: 35171649.

3. McAfee A, Metz BN, Milone JP, Foster LJ, Tarpy DR. Drone honey bees are disproportionately sensitive to abiotic stressors despite expressing high levels of stress response proteins. Commun Biol. 2022 Feb 17;5(1):141. doi: 10.1038/s42003-022-03092-7. PMID: 35177754.

4. Silva BC, Aguilar AP, Dutra L, Moon KM, Sébastien A, Foster LJ, Mendes TAO, de Oliveira Barros Ribon A. Proteomic Profiles of Staphylococcus aureus Strains Associated with Subclinical Bovine Mastitis. Curr Microbiol. 2022 Feb 12;79(4):101. doi: 10.1007/s00284-022-02796-7. PMID: 35150342.

Feb 14, Pubcrawler Hits:

1. Dixon-McDougall T, Brown CJ. Multiple distinct domains of human XIST are required to coordinate gene silencing and subsequent heterochromatin formation. Epigenetics Chromatin. 2022 Feb 4;15(1):6. doi: 10.1186/s13072-022-00438-7. PMID: 35120578; PMCID: PMC8815261.

2. Ludwig DS, Aronne LJ, Astrup A, de Cabo R, Cantley LC, Friedman MI, Heymsfield SB, Johnson JD, King JC, Krauss RM, Lieberman DE, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Ebbeling CB. Reply to A Drewnowski et al, O Devinsky, D A Booth and E L Gibson, and D J Millward. Am J Clin Nutr. 2022 Feb 9;115(2):595-597. doi: 10.1093/ajcn/nqab385. PMID: 35139162.

3. Skovsø S, Panzhinskiy E, Kolic J, Cen HH, Dionne DA, Dai XQ, Sharma RB, Elghazi L, Ellis CE, Faulkner K, Marcil SAM, Overby P, Noursadeghi N, Hutchinson D, Hu X, Li H, Modi H, Wildi JS, Botezelli JD, Noh HL, Suk S, Gablaski B, Bautista A, Kim R, Cras-Méneur C, Flibotte S, Sinha S, Luciani DS, Nislow C, Rideout EJ, Cytrynbaum EN, Kim JK, Bernal-Mizrachi E, Alonso LC, MacDonald PE, Johnson JD. Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance. Nat Commun. 2022 Feb 8;13(1):735. doi: 10.1038/s41467-022-28039-8. PMID: 35136059.

4. Dalwadi U, Mannar D, Zierhut F, Yip CK. Biochemical and Structural Characterization of Human Core Elongator and Its Subassemblies. ACS Omega. 2022 Jan 18;7(4):3424-3433. doi: 10.1021/acsomega.1c05719. PMID: 35128251; PMCID: PMC8811885.

Feb 7, Pubcrawler Hits:

1. Sharon AJ, Filyk HA, Fonseca NM, Simister RL, Filler RB, Yuen W, Hardman BK, Robinson HG, Seo JH, Rocha-Pereira J, Welch I, Neyts J, Wilen CB, Crowe SA, Osborne LC. Restriction of viral replication, rather than T cell immunopathology, drives lethality in MNV CR6-infected STAT1-deficient mice. J Virol. 2022 Feb 2:jvi0206521. doi: 10.1128/jvi.02065-21. Epub ahead of print. PMID: 35107369.

2. Bodnar TS, Lee C, Wong A, Rubin I, Wegener Parfrey L, Weinberg J. Evidence for long-lasting alterations in the fecal microbiota following prenatal alcohol exposure. Alcohol Clin Exp Res. 2022 Jan 31. doi: 10.1111/acer.14784. Epub ahead of print. PMID: 35102585.

3. Sahile HA, Williams DE, de Voogd NJ, Ko M, Andersen RJ, Av-Gay Y. Screening of diverse marine invertebrate extracts identified Lissoclinotoxin F, Discodermin B, and other anti-Mycobacterium tuberculosis active compounds. J Antibiot (Tokyo). 2022 Jan 28. doi: 10.1038/s41429-022-00507-9. Epub ahead of print. PMID: 35091665.

4. Borba RS, Hoover SE, Currie RW, Giovenazzo P, Guarna MM, Foster LJ, Zayed A, Pernal SF. Phenomic analysis of the honey bee pathogen-web and its dynamics on colony productivity, health and social immunity behaviors. PLoS One. 2022 Jan 31;17(1):e0263273. doi: 10.1371/journal.pone.0263273. PMID: 35100308; PMCID: PMC8803170.

Jan 31, Pubcrawler Hits:

1. Zhang H, Perez-Garcia P, Dierkes RF, Applegate V, Schumacher J, Chibani CM, Sternagel S, Preuss L, Weigert S, Schmeisser C, Danso D, Pleiss J, Almeida A, Höcker B, Hallam SJ, Schmitz RA, Smits SHJ, Chow J, Streit WR. The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity. Front Microbiol. 2022 Jan 5;12:803896. doi: 10.3389/fmicb.2021.803896. PMID: 35069509; PMCID: PMC8767016.

2. Gil KN, Vogl AW, Shadwick RE. Anatomical mechanism for protecting the airway in the largest animals on earth. Curr Biol. 2022 Jan 7:S0960-9822(21)01727-9. doi: 10.1016/j.cub.2021.12.040. Epub ahead of print. PMID: 35063119.

3. Hippmann AA, Schuback N, Moon KM, McCrow JP, Allen AE, Foster LF, Green BR, Maldonado MT. Proteomic analysis of metabolic pathways supports chloroplast-mitochondria cross-talk in a Cu-limited diatom. Plant Direct. 2022 Jan 20;6(1):e376. doi: 10.1002/pld3.376. PMID: 35079683; PMCID: PMC8777261.

Jan 24, Pubcrawler Hits:

1. Leatherdale A, Stukas S, Lei V, West HE, Campbell CJ, Hoiland RL, Cooper J, Wellington CL, Sekhon MS, Pryzdial ELG, Conway EM. Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality. Med Microbiol Immunol. 2022 Jan 16:1–12. doi: 10.1007/s00430-021-00725-2. Epub ahead of print. PMID: 35034207; PMCID: PMC8761108.

2. Gawish R, Starkl P, Pimenov L, Hladik A, Lakovits K, Oberndorfer F, Cronin SJ, Ohradanova-Repic A, Wirnsberger G, Agerer B, Endler L, Capraz T, Perthold JW, Cikes D, Koglgruber R, Hagelkruys A, Montserrat N, Mirazimi A, Boon L, Stockinger H, Bergthaler A, Oostenbrink C, Penninger JM, Knapp S. ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology. Elife. 2022 Jan 13;11:e74623. doi: 10.7554/eLife.74623. PMID: 35023830; PMCID: PMC8776253.

Jan 17, Pubcrawler Hits:

1. Sheikh A, Jackson J, Shim HB, Yau C, Seo JH, Abraham N. Selective dependence on IL-7 for antigen-specific CD8 T cell responses during airway influenza infection. Sci Rep. 2022 Jan 7;12(1):135. doi: 10.1038/s41598-021-03936-y. PMID: 34997007; PMCID: PMC8741933.

2. Park JY, Won HY, DiPalma DT, Kim HK, Kim TH, Li C, Sato N, Hong C, Abraham N, Gress RE, Park JH. In vivo availability of the cytokine IL-7 constrains the survival and homeostasis of peripheral iNKT cells. Cell Rep. 2022 Jan 11;38(2):110219. doi: 10.1016/j.celrep.2021.110219. PMID: 35021100.

3. Kirby MP, Stevenson C, Worrall LJ, Chen Y, Young C, Youm J, Strynadka NCJ, Allan DW, Jan E. The hinge region of the Israeli acute paralysis virus internal ribosome entry site directs ribosomal positioning, translational activity and virus infection. J Virol. 2022 Jan 12:JVI0133021. doi: 10.1128/JVI.01330-21. Epub ahead of print. PMID: 35019716.

4. Gentile F, Fernandez M, Ban F, Ton AT, Mslati H, Perez CF, Leblanc E, Yaacoub JC, Gleave J, Stern A, Wong B, Jean F, Strynadka N, Cherkasov A. Automated discovery of noncovalent inhibitors of SARS-CoV-2 main protease by consensus Deep Docking of 40 billion small molecules. Chem Sci. 2021 Nov 17;12(48):15960-15974. doi: 10.1039/d1sc05579h. PMID: 35024120; PMCID: PMC8672713.

5. Baradaran-Heravi A, Bauer CC, Pickles IB, Hosseini-Farahabadi S, Balgi AD, Choi K, Linley DM, Beech DJ, Roberge M, Bon RS. Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. J Biol Chem. 2022 Jan 6:101546. doi: 10.1016/j.jbc.2021.101546. Epub ahead of print. PMID: 34999117.

6. Shademani A, Jackson JK, Thompson CJ, Chiao M. Controlled and localized antibiotics delivery using magnetic-responsive beads for synergistic treatment of orthopedic infection. J Biomed Mater Res A. 2022 Jan 8. doi: 10.1002/jbm.a.37350. Epub ahead of print. PMID: 34997805.

7. Kuba K, Yamaguchi T, Penninger JM. Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19. Front Immunol. 2021 Dec 22;12:732690. doi: 10.3389/fimmu.2021.732690. PMID: 35003058; PMCID: PMC8727358.

8. Kokotović T, Lenartowicz EM, Langeslag M, Ciotu CI, Fell CW, Scaramuzza A, Fischer MJM, Kress M, Penninger JM, Nagy V. Transcription factor Mesenchyme Homeobox Protein 2 (MEOX2) modulates nociceptor function. FEBS J. 2022 Jan 13. doi: 10.1111/febs.16347. Epub ahead of print. PMID: 35029322.

9. Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A; CONCOR-1 Study Group, Arnold DM. Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nat Med. 2022 Jan 12:1. doi: 10.1038/s41591-021-01667-1. Epub ahead of print. Erratum for: Nat Med. 2021 Nov;27(11):2012-2024. PMID: 35022578; PMCID: PMC8753330.

Jan 10, Pubcrawler Hits:

1. Jun D, Zhang S, Grzędowski AJ, Mahey A, Beatty JT, Bizzotto D. Purification and preparation of Rhodobacter sphaeroides reaction centers for photocurrent measurements and atomic force microscopy characterization. STAR Protoc. 2021 Dec 16;3(1):101044. doi: 10.1016/j.xpro.2021.101044. PMID: 34977685; PMCID: PMC8689352.

2. Chadwick GL, Skennerton CT, Laso-Pérez R, Leu AO, Speth DR, Yu H, Morgan-Lang C, Hatzenpichler R, Goudeau D, Malmstrom R, Brazelton WJ, Woyke T, Hallam SJ, Tyson GW, Wegener G, Boetius A, Orphan VJ. Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea. PLoS Biol. 2022 Jan 5;20(1):e3001508. doi: 10.1371/journal.pbio.3001508. Epub ahead of print. PMID: 34986141.

3. Wright T, Vlok M, Shapira T, Olmstead AD, Jean F, Wolf MO. Photodynamic and Contact Killing Polymeric Fabric Coating for Bacteria and SARS-CoV-2. ACS Appl Mater Interfaces. 2022 Jan 3. doi: 10.1021/acsami.1c14178. Epub ahead of print. PMID: 34978405.

4. Price HR, Pang N, Kim H, Coughtrie MWH, Collier AC. Protective placental inflammatory and oxidative stress responses are attenuated in the context of twin pregnancy and chorioamnionitis in assisted reproduction. J Assist Reprod Genet. 2022 Jan 6. doi: 10.1007/s10815-021-02371-2. Epub ahead of print. PMID: 34988769.

5. Ito T, Kubiura-Ichimaru M, Murakami Y, Bogutz AB, Lefebvre L, Suetake I, Tajima S, Tada M. DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells. PLoS One. 2022 Jan 5;17(1):e0262277. doi: 10.1371/journal.pone.0262277. PMID: 34986190; PMCID: PMC8730390.

6. Mclean MA, Scoten OC, Yu W, Ye XY, Petrie J, Church PT, Soraisham AS, Mirea LS, Weinberg J, Synnes AR, O'Brien K, Grunau RE. Lower Maternal Chronic Physiological Stress and Better Child Behavior at 18 months: Follow-up of a Cluster Randomized Trial of NICU Family Integrated Care. J Pediatr. 2021 Dec 28:S0022-3476(21)01262-2. doi: 10.1016/j.jpeds.2021.12.055. Epub ahead of print. PMID: 34971651.

7. Sexton DL, Burgold S, Schertel A, Tocheva EI. Super-resolution confocal cryo-CLEM with cryo-FIB milling for in situ imaging of Deinococcus radiodurans. Curr Res Struct Biol. 2021 Dec 13;4:1-9. doi: 10.1016/j.crstbi.2021.12.001. PMID: 34977598; PMCID: PMC8688812.

8. Capraz T, Kienzl NF, Laurent E, Perthold JW, Föderl-Höbenreich E, Grünwald-Gruber C, Maresch D, Monteil V, Niederhöfer J, Wirnsberger G, Mirazimi A, Zatloukal K, Mach L, Penninger JM, Oostenbrink C, Stadlmann J. Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor. Elife. 2021 Dec 20;10:e73641. doi: 10.7554/eLife.73641. PMID: 34927585; PMCID: PMC8730730.

9. González-Cuesta M, Sidhu P, Ashmus RA, Males A, Proceviat C, Madden Z, Rogalski JC, Busmann JA, Foster LJ, García Fernández JM, Davies GJ, Ortiz Mellet C, Vocadlo DJ. Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications. J Am Chem Soc. 2022 Jan 5. doi: 10.1021/jacs.1c10504. Epub ahead of print. PMID: 34985906.

Jan 3, Pubcrawler Hits:

1. Juang LJ, Hur WS, Silva LM, Strilchuk AW, Francisco B, Leung J, Robertson MK, Groeneveld DJ, La Prairie B, Chun EM, Cap AP, Luyendyk JP, Palumbo JS, Cullis PR, Bugge TH, Flick MJ, Kastrup CJ. Suppression of fibrin(ogen)-driven pathologies through controlled knockdown by lipid nanoparticle delivery of siRNA. Blood. 2021 Dec 27:blood.2021014559. doi: 10.1182/blood.2021014559. Epub ahead of print. PMID: 34958662.

2. Molday RS, Garces FA, Scortecci JF, Molday LL. Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration. Prog Retin Eye Res. 2021 Dec 23:101036. doi: 10.1016/j.preteyeres.2021.101036. Epub ahead of print. PMID: 34954332.

3. Arslanova A, Shafaattalab S, Ye K, Asghari P, Lin L, Kim B, Roston TM, Hove-Madsen L, Van Petegem F, Sanatani S, Moore E, Lynn F, Søndergaard M, Luo Y, Chen SRW, Tibbits GF. Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia. Curr Protoc. 2021 Dec;1(12):e320. doi: 10.1002/cpz1.320. PMID: 34958715.

4. Sugioka K. Symmetry-breaking of animal cytokinesis. Semin Cell Dev Biol. 2021 Dec 23:S1084-9521(21)00316-5. doi: 10.1016/j.semcdb.2021.12.008. Epub ahead of print. PMID: 34955355.


Dec 27, Pubcrawler Hits:

1. Jurczak A, Delay L, Barbier J, Simon N, Krock E, Sandor K, Agalave NM, Rudjito R, Wigerblad G, Rogóż K, Briat A, Miot-Noirault E, Martinez-Martinez A, Brömme D, Grönwall C, Malmström V, Klareskog L, Khoury S, Ferreira T, Labrum B, Deval E, Jiménez-Andrade JM, Marchand F, Svensson CI. Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity and ASIC3-dependent sensitization. Pain. 2021 Nov 19. doi: 10.1097/j.pain.0000000000002543. Epub ahead of print. PMID: 34924556.

2. Cen HH, Hussein B, Botezelli JD, Wang S, Zhang JA, Noursadeghi N, Jessen N, Rodrigues B, Timmons JA, Johnson JD. Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance. FASEB J. 2022 Jan;36(1):e22088. doi: 10.1096/fj.202100497RR. PMID: 34921686.

3. Urtatiz O, Haage A, Tanentzapf G, Van Raamsdonk CD. Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma. Elife. 2021 Dec 23;10:e71825. doi: 10.7554/eLife.71825. Epub ahead of print. PMID: 34939927.

4. Lussier AA, Bodnar TS, Weinberg J. Intersection of Epigenetic and Immune Alterations: Implications for Fetal Alcohol Spectrum Disorder and Mental Health. Front Neurosci. 2021 Dec 3;15:788630. doi: 10.3389/fnins.2021.788630. PMID: 34924946; PMCID: PMC8680672.

5. Richter A, Narula G, Rudolph I, Seidel RW, Wagner C, Av-Gay Y, Imming P. Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis. ChemMedChem. 2021 Dec 23:e202100733. doi: 10.1002/cmdc.202100733. Epub ahead of print. PMID: 34939744.

Dec 20, Pubcrawler Hits:

1. Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin YJ, Colwill K, Rathod B, Greenberg B, Gingras AC, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV. Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada. Transfusion. 2021 Dec 14. doi: 10.1111/trf.16772. Epub ahead of print. PMID: 34907536.

2. Rossi D, Lorenzini S, Pierantozzi E, Van Petegem F, Amadsun DO, Sorrentino V. Multiple regions of junctin drive interaction with calsequestrin-1 and localization at triads in skeletal muscle. J Cell Sci. 2021 Dec 16:jcs.259185. doi: 10.1242/jcs.259185. Epub ahead of print. PMID: 34913055.

3. Goel N, Philippe TJ, Chang J, Koblanski ME, Viau V. Cellular and serotonergic correlates of habituated neuroendocrine responses in male and female rats. Psychoneuroendocrinology. 2021 Nov 20;136:105599. doi: 10.1016/j.psyneuen.2021.105599. Epub ahead of print. PMID: 34891046.

Dec 13, Pubcrawler Hits:

1. Chen IS, Eldstrom J, Fedida D, Kubo Y. A novel ion conducting route besides the central pore in an inherited mutant of G-protein-gated inwardly rectifying K+ channel. J Physiol. 2021 Dec 8. doi: 10.1113/JP282430. Epub ahead of print. PMID: 34881429.

2. Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H. Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis. Transfusion. 2021 Dec 8. doi: 10.1111/trf.16757. Epub ahead of print. PMID: 34877683.

3. Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H. Assessing red blood cell deformability from microscopy images using deep learning. Lab Chip. 2021 Dec 7. doi: 10.1039/d1lc01006a. Epub ahead of print. PMID: 34874395.

4. Knuff-Janzen K, Serapio-Palacios A, McCoy J, Krekhno Z, Moon KM, Deng W, Foster LJ, Finlay BB. Quantitative proteomic screen identifies annexin A2 as a host target for Salmonella pathogenicity island-2 effectors SopD2 and PipB2. Sci Rep. 2021 Dec 8;11(1):23630. doi: 10.1038/s41598-021-02795-x. PMID: 34880286.

5. Flibotte S, Edgley M, Au V, Moerman DG. Whole Genome Sequencing identifies reciprocal translocation hT2(I;III) breakpoints. MicroPubl Biol. 2021 Dec 9;2021:10.17912/micropub.biology.000505. doi: 10.17912/micropub.biology.000505. PMID: 34909608; PMCID: PMC8662349.

6. Edgley ML, Flibotte S, Moerman DG. Sequenced Breakpoints of Crossover Suppressor/Inversion qC1. MicroPubl Biol. 2021 Nov 3;2021:10.17912/micropub.biology.000494. doi: 10.17912/micropub.biology.000494. PMID: 34746683; PMCID: PMC8567092.

7. Li-Leger E, Feichtinger R, Flibotte S, Holzkamp H, Schnabel R, Moerman DG. Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections. G3 (Bethesda). 2021 Dec 8;11(12):jkab328. doi: 10.1093/g3journal/jkab328. PMID: 34550348; PMCID: PMC8664450.

Dec 6, Pubcrawler Hits:

1. Kamanzi A, Gu Y, Tahvildari R, Friedenberger Z, Zhu X, Berti R, Kurylowicz M, Witzigmann D, Kulkarni JA, Leung J, Andersson J, Dahlin A, Höök F, Sutton M, Cullis PR, Leslie S. Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles. ACS Nano. 2021 Nov 29. doi: 10.1021/acsnano.1c04862. Epub ahead of print. PMID: 34843205.

2. Musso PY, Junca P, Gordon MD. A neural circuit linking two sugar sensors regulates satiety-dependent fructose drive in Drosophila. Sci Adv. 2021 Dec 3;7(49):eabj0186. doi: 10.1126/sciadv.abj0186. Epub 2021 Dec 1. PMID: 34851668; PMCID: PMC8635442.

3. Mette Frøbert A, Brohus M, Toews JNC, Round P, Fröbert O, Hammond GL, Overgaard MT. Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin. FEBS Open Bio. 2021 Dec 2. doi: 10.1002/2211-5463.13341. Epub ahead of print. PMID: 34855305.

4. Ramzy A, Thompson DM, Ward-Hartstonge KA, Ivison S, Cook L, Garcia RV, Loyal J, Kim PTW, Warnock GL, Levings MK, Kieffer TJ. Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes. Cell Stem Cell. 2021 Dec 2;28(12):2047-2061.e5. doi: 10.1016/j.stem.2021.10.003. PMID: 34861146.

5. Hoesli CA, Kieffer TJ. Pancreatic islets in bed with microvasculature-companions for life. Cell Rep Med. 2021 Nov 16;2(11):100454. doi: 10.1016/j.xcrm.2021.100454. PMID: 34841297; PMCID: PMC8607006.

6. Erener S, Ellis CE, Ramzy A, Glavas MM, O'Dwyer S, Pereira S, Wang T, Pang J, Bruin JE, Riedel MJ, Baker RK, Webber TD, Lesina M, Blüher M, Algül H, Kopp JL, Herzig S, Kieffer TJ. Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice. Cell Rep Med. 2021 Nov 11;2(11):100434. doi: 10.1016/j.xcrm.2021.100434. PMID: 34841287; PMCID: PMC8606901.

7. Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC. Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing. Nat Commun. 2021 Dec 2;12(1):7020. doi: 10.1038/s41467-021-27345-x. PMID: 34857746.

8. Overall CM. A Flickering Light at the End of the Pandemic Tunnel. J Proteome Res. 2021 Dec 3;20(12):5223-5226. doi: 10.1021/acs.jproteome.1c00866. PMID: 34856807.

9. Lussier AA, Bodnar TS, Moksa M, Hirst M, Kobor MS, Weinberg J. Prenatal Adversity Alters the Epigenetic Profile of the Prefrontal Cortex: Sexually Dimorphic Effects of Prenatal Alcohol Exposure and Food-Related Stress. Genes (Basel). 2021 Nov 9;12(11):1773. doi: 10.3390/genes12111773. PMID: 34828381; PMCID: PMC8622940.

Nov 29, Pubcrawler Hits: 

1. Mahto JK, Neetu N, Waghmode B, Kuatsjah E, Sharma M, Sircar D, Sharma AK, Tomar S, Eltis LD, Kumar P. Molecular insights into substrate recognition and catalysis by phthalate dioxygenase from Comamonas testosteroni. J Biol Chem. 2021 Nov 17:101416. doi: 10.1016/j.jbc.2021.101416. Epub ahead of print. PMID: 34800435.

2. Lincez PJ, Shanina I, Horwitz MS. Changes in MDA5 and TLR3 Sensing of the Same Diabetogenic Virus Result in Different Autoimmune Disease Outcomes. Front Immunol. 2021 Nov 5;12:751341. doi: 10.3389/fimmu.2021.751341. PMID: 34804036; PMCID: PMC8602094.

3. Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, An J, Saku A, Nukiwa R, Utsumi D, Kiso M, Yasuhara A, Poon VK, Chan CC, Fujino Y, Motoyama S, Nagata S, Penninger JM, Kamada H, Yuen KY, Kamitani W, Maeda K, Kawaoka Y, Yasutomi Y, Imai Y, Kuba K. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury. Nat Commun. 2021 Nov 23;12(1):6791. doi: 10.1038/s41467-021-27097-8. PMID: 34815389.

Nov 22, Pubcrawler Hits: 

1. Rapala J, Miller B, Garcia M, Dolan M, Bockman M, Hansson M, Russell DA, Garlena RA, Cresawn SG, Westbye AB, Beatty JT, Alvey RM, Bollivar DW. Genomic diversity of bacteriophages infecting Rhodobacter capsulatus and their relatedness to its gene transfer agent RcGTA. PLoS One. 2021 Nov 18;16(11):e0255262. doi: 10.1371/journal.pone.0255262. PMID: 34793465; PMCID: PMC8601537.

2. Phan HD, Longjohn MN, Gormley DJB, Smith RH, Dang-Lawson M, Matsuuchi L, Gold MR, Christian SL. CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles. J Immunol. 2021 Nov 12:ji2100025. doi: 10.4049/jimmunol.2100025. Epub ahead of print. PMID: 34772696.

3. Asghari P, Scriven DRL, Shahrasebi S, Moore EDW. RYR2 phosphomutants show that the tetramers and the junctional sarcoplasmic reticulum form a structural syncytium. J Gen Physiol. 2022 Sep 5;154(9):e2021ecc5. doi: 10.1085.jgp/2021ecc5. Epub 2021 Nov 12. PMID: 34766976.

4. Osborne LC. Protecting your gut feelings: How intestinal infections keep things moving. Neuron. 2021 Nov 17;109(22):3545-3547. doi: 10.1016/j.neuron.2021.10.037. PMID: 34793706.

5. Zhang J, Singh DP, Ko CY, Nikolaienko R, Wong King Yuen SM, Schwarz JA, Treinen LM, Tung CC, Rožman K, Svensson B, Aldrich CC, Zima AV, Thomas DD, Bers DM, Launikonis BS, Van Petegem F, Cornea RL. Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening. J Biol Chem. 2021 Nov 15:101412. doi: 10.1016/j.jbc.2021.101412. Epub ahead of print. PMID: 34793835.

6. Ma R, Haji-Ghassemi O, Ma D, Jiang H, Lin L, Xu T, Murayama T, Moussian B, Van Petegem F, Yuchi Z. Structural basis for diamide modulation of ryanodine receptor. J Gen Physiol. 2022 Sep 5;154(9):e2021ecc17. doi: 10.1085/jgp.2021ecc17. Epub 2021 Nov 12. PMID: 34766989.

7. Yu ACY, Volkers G, Jongkees SAK, Worrall LJ, Withers SG, Strynadka NCJ. Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases. Glycobiology. 2021 Nov 17:cwab094. doi: 10.1093/glycob/cwab094. Epub ahead of print. PMID: 34792586.

8. Sexton DL, Chen G, Kara Murdoch F, Hashimi A, Löffler FE, Tocheva EI. Ultrastructure of organohalide-respiring Dehalococcoidia revealed by cryo-electron tomography. Appl Environ Microbiol. 2021 Nov 17:AEM0190621. doi: 10.1128/AEM.01906-21. Epub ahead of print. PMID: 34788060.

9. Ctortecka C, Krššáková G, Stejskal K, Penninger JM, Mendjan S, Mechtler K, Stadlmann J. Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition. Mol Cell Proteomics. 2021 Nov 15:100177. doi: 10.1016/j.mcpro.2021.100177. Epub ahead of print. PMID: 34793982.

Nov 15, Pubcrawler Hits:

1. Lien KA, Dinshaw K, Nichols RJ, Cassidy-Amstutz C, Knight M, Singh R, Eltis LD, Savage DF, Stanley SA. A nanocompartment system contributes to defense against oxidative stress in Mycobacterium tuberculosis. Elife. 2021 Nov 9;10:e74358. doi: 10.7554/eLife.74358. Epub ahead of print. PMID: 34751132.

2. Gomez-Diaz C, Jonsson G, Schodl K, Deszcz L, Bestehorn A, Eislmayr K, Almagro J, Kavirayani A, Seida M, Fennell LM, Hagelkruys A, Kovarik P, Penninger JM, Ikeda F. The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains. iScience. 2021 Oct 8;24(11):103241. doi: 10.1016/j.isci.2021.103241. PMID: 34755089; PMCID: PMC8561004.

Nov 8, Pubcrawler Hits:

1. Vuong TV, Singh R, Eltis LD, Master ER. The Comparative Abilities of a Small Laccase and a Dye-Decoloring Peroxidase From the Same Bacterium to Transform Natural and Technical Lignins. Front Microbiol. 2021 Oct 18;12:723524. doi: 10.3389/fmicb.2021.723524. PMID: 34733245; PMCID: PMC8559727.

2. Fung SY, Lu HY, Sharma M, Sharma AA, Saferali A, Jia A, Abraham L, Klein T, Gold MR, Noterangelo LD, Overall CM, Turvey SE. MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness. Front Immunol. 2021 Oct 14;12:749794. doi: 10.3389/fimmu.2021.749794. PMID: 34721419; PMCID: PMC8552041.

3. Morse ZJ, Horwitz MS. Virus Infection Is an Instigator of Intestinal Dysbiosis Leading to Type 1 Diabetes. Front Immunol. 2021 Oct 15;12:751337. doi: 10.3389/fimmu.2021.751337. PMID: 34721424; PMCID: PMC8554326.

4. Grondin JM, Déjean G, Van Petegem F, Brumer H. Cell-surface xyloglucan recognition and hydrolysis by the human gut commensal Bacteroides uniformis. Appl Environ Microbiol. 2021 Nov 3:AEM0156621. doi: 10.1128/AEM.01566-21. Epub ahead of print. PMID: 34731054.

5. Kawahara R, Chernykh A, Alagesan K, Bern M, Cao W, Chalkley RJ, Cheng K, Choo MS, Edwards N, Goldman R, Hoffmann M, Hu Y, Huang Y, Kim JY, Kletter D, Liquet B, Liu M, Mechref Y, Meng B, Neelamegham S, Nguyen-Khuong T, Nilsson J, Pap A, Park GW, Parker BL, Pegg CL, Penninger JM, Phung TK, Pioch M, Rapp E, Sakalli E, Sanda M, Schulz BL, Scott NE, Sofronov G, Stadlmann J, Vakhrushev SY, Woo CM, Wu HY, Yang P, Ying W, Zhang H, Zhang Y, Zhao J, Zaia J, Haslam SM, Palmisano G, Yoo JS, Larson G, Khoo KH, Medzihradszky KF, Kolarich D, Packer NH, Thaysen-Andersen M. Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nat Methods. 2021 Nov;18(11):1304-1316. doi: 10.1038/s41592-021-01309-x. Epub 2021 Nov 1. PMID: 34725484.

Nov 1, Pubcrawler Hits:

1. Huang YH, Kuo CH, Peng IC, Chang YS, Tseng SH, Conway EM, Wu HL. Recombinant thrombomodulin domain 1 rescues pathological angiogenesis by inhibition of HIF-1α-VEGF pathway. Cell Mol Life Sci. 2021 Oct 27. doi: 10.1007/s00018-021-03950-3. Epub ahead of print. PMID: 34705054.

2. Traving SJ, Kellogg CTE, Ross T, McLaughlin R, Kieft B, Ho GY, Peña A, Krzywinski M, Robert M, Hallam SJ. Prokaryotic responses to a warm temperature anomaly in northeast subarctic Pacific waters. Commun Biol. 2021 Oct 22;4(1):1217. doi: 10.1038/s42003-021-02731-9. PMID: 34686760.

3. Wat LW, Chowdhury ZS, Millington JW, Biswas P, Rideout EJ. Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway. Elife. 2021 Oct 21;10:e72350. doi: 10.7554/eLife.72350. Epub ahead of print. PMID: 34672260.

4. Has C, Sayar SB, Zheng S, Chacón-Solano E, Condrat I, Yadav A, Roberge M, Laguzzi FL. Read-through for nonsense mutations in type XVII collagen deficient junctional epidermolysis bullosa. J Invest Dermatol. 2021 Oct 18:S0022-202X(21)02309-5. doi: 10.1016/j.jid.2021.09.018. Epub ahead of print. PMID: 34673051.

5. Yang X, Toyofuku WM, Scott MD. Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation. Arch Immunol Ther Exp (Warsz). 2021 Oct 22;69(1):30. doi: 10.1007/s00005-021-00634-5. PMID: 34677693; PMCID: PMC8536625.

Oct 25, Pubcrawler Hits:

1. Davidson AB, Holmden C, Nomosatryo S, Henny C, Francois R, Crowe SA. Cr Isotopes and the Engineered Attenuation of Cr(VI)-Rich Runoff. Environ Sci Technol. 2021 Oct 20. doi: 10.1021/acs.est.1c01714. Epub ahead of print. PMID: 34669373.

2. Omenn GS, Lane L, Overall CM, Paik YK, Cristea IM, Corrales FJ, Lindskog C, Weintraub S, Roehrl MHA, Liu S, Bandeira N, Srivastava S, Chen YJ, Aebersold R, Moritz RL, Deutsch EW. Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project. J Proteome Res. 2021 Oct 20. doi: 10.1021/acs.jproteome.1c00590. Epub ahead of print. PMID: 34670092.

Oct 18, Pubcrawler Hits:

1. Ma Y, Hadjesfandiari N, Doschak M, Devine D, Tonelli M, Unsworth L. Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma. Langmuir. 2021 Oct 13. doi: 10.1021/acs.langmuir.1c01783. Epub ahead of print. PMID: 34644097.

2. Eldstrom J, McAfee DA, Dou Y, Wang Y, Fedida D. ML277 regulates KCNQ1 single-channel amplitudes and kinetics, modified by voltage sensor state. J Gen Physiol. 2021 Dec 6;153(12):e202112969. doi: 10.1085/jgp.202112969. Epub 2021 Oct 12. PMID: 34636894.

3. Yu HB, Yang H, Allaire JM, Ma C, Graef FA, Mortha A, Liang Q, Bosman ES, Reid GS, Waschek JA, Osborne LC, Sokol H, Vallance BA, Jacobson K. Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2106634118. doi: 10.1073/pnas.2106634118. PMID: 34625492.

4. Mank JE, Rideout EJ. Developmental mechanisms of sex differences: from cells to organisms. Development. 2021 Oct 1;148(19):dev199750. doi: 10.1242/dev.199750. Epub 2021 Oct 14. PMID: 34647574.

5. Kokotović T, Langeslag M, Lenartowicz EM, Manion J, Fell CW, Alehabib E, Tafakhori A, Darvish H, Bellefroid EJ, Neely GG, Kress M, Penninger JM, Nagy V. PRDM12 Is Transcriptionally Active and Required for Nociceptor Function Throughout Life. Front Mol Neurosci. 2021 Sep 27;14:720973. doi: 10.3389/fnmol.2021.720973. PMID: 34646120; PMCID: PMC8502974.

Oct 11, Pubcrawler Hits:

1. Yeh HH, Yu K, Vappala S, Kalathottukaren MT, Abbina S, Luo HD, Grecov D, Kizhakkedathu JN. Rheological and clot microstructure evaluation of heparin neutralization by UHRA and protamine. J Mech Behav Biomed Mater. 2021 Sep 24;124:104851. doi: 10.1016/j.jmbbm.2021.104851. Epub ahead of print. PMID: 34600430.

2. Janssen SM, Lorincz MC. Interplay between chromatin marks in development and disease. Nat Rev Genet. 2021 Oct 4. doi: 10.1038/s41576-021-00416-x. Epub ahead of print. PMID: 34608297.

3. Scortecci JF, Molday LL, Curtis SB, Garces FA, Panwar P, Van Petegem F, Molday RS. Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun. 2021 Oct 8;12(1):5902. doi: 10.1038/s41467-021-26161-7. PMID: 34625547.

4. Pablos I, Machado Y, de Jesus HCR, Mohamud Y, Kappelhoff R, Lindskog C, Vlok M, Bell PA, Butler GS, Grin PM, Cao QT, Nguyen JP, Solis N, Abbina S, Rut W, Vederas JC, Szekely L, Szakos A, Drag M, Kizhakkedathu JN, Mossman K, Hirota JA, Jan E, Luo H, Banerjee A, Overall CM. Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome. Cell Rep. 2021 Oct 26;37(4):109892. doi: 10.1016/j.celrep.2021.109892. Epub 2021 Oct 9. PMID: 34672947; PMCID: PMC8501228.

Oct 4, Pubcrawler Hits:

1. Hoffarth ER, Caddell Haatveit K, Kuatsjah E, MacNeil GA, Saroya S, Walsby CJ, Eltis LD, Houk KN, Garcia-Borràs M, Ryan KS. A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2012591118. doi: 10.1073/pnas.2012591118. PMID: 34580201.

2. Drayton M, Alford MA, Pletzer D, Haney EF, Machado Y, Luo HD, Overall CM, Kizhakkedathu JN, Hancock REW, Straus SK. Enzymatically releasable polyethylene glycol - Host defense peptide conjugates with improved activity and biocompatibility. J Control Release. 2021 Sep 28:S0168-3659(21)00514-9. doi: 10.1016/j.jconrel.2021.09.035. Epub ahead of print. PMID: 34597746.

3. Li T, Yu D, Oak HC, Zhu B, Wang L, Jiang X, Molday RS, Kriegstein A, Piao X. Phospholipid-flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure. EMBO J. 2021 Sep 29:e107915. doi: 10.15252/embj.2021107915. Epub ahead of print. PMID: 34585770.

Sep 27, Pubcrawler Hits:

1. Al Fayez N, Böttger R, Rouhollahi E, Cullis PR, Witzigmann D, Li SD. Improved Liver Delivery of Primaquine by Phospholipid-Free Small Unilamellar Vesicles with Reduced Hemolytic Toxicity. Mol Pharm. 2021 Sep 21. doi: 10.1021/acs.molpharmaceut.1c00520. Epub ahead of print. PMID: 34546758.

2. Arif AA, Huang YH, Freeman SA, Atif J, Dean P, Lai JCY, Blanchet MR, Wiegand KC, McNagny KM, Underhill TM, Gold MR, Johnson P, Roskelley CD. Inflammation-induced metastatic colonization of the lung is facilitated by HGF-secreting monocyte-derived macrophages. Mol Cancer Res. 2021 Sep 23:molcanres.0009.2021. doi: 10.1158/1541-7786.MCR-21-0009. Epub ahead of print. PMID: 34556524.

3. Glavas MM, Lee AY, Miao I, Yang F, Majid M, O'Dwyer SM, Kieffer TJ. Developmental Timing of High Fat Diet Exposure Impacts Glucose Homeostasis in Mice in a Sex-Specific Manner. Diabetes. 2021 Sep 20:db210310. doi: 10.2337/db21-0310. Epub ahead of print. PMID: 34544729.

4. Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Development of a novel, pan-variant aerosol intervention for COVID-19. bioRxiv [Preprint]. 2021 Sep 14:2021.09.14.459961. doi: 10.1101/2021.09.14.459961. PMID: 34545364; PMCID: PMC8452093.

5. Christopher JA, Stadler C, Martin CE, Morgenstern M, Pan Y, Betsinger CN, Rattray DG, Mahdessian D, Gingras AC, Warscheid B, Lehtiö J, Cristea IM, Foster LJ, Emili A, Lilley KS. Subcellular proteomics. Nat Rev Methods Primers. 2021;1:32. doi: 10.1038/s43586-021-00029-y. Epub 2021 Apr 29. PMID: 34549195; PMCID: PMC8451152.

6. Bixby MEF, Polinsky M, Scarlett R, Higo H, Common J, Hoover SE, Foster LJ, Zayed A, Cunningham M, Guarna MM. Impacts of COVID-19 on Canadian Beekeeping: Survey Results and a Profitability Analysis. J Econ Entomol. 2021 Sep 21:toab180. doi: 10.1093/jee/toab180. Epub ahead of print. PMID: 34545929.

Sep 20, Pubcrawler Hits:

1. Zhang XX, Young JW, Foster LJ, Duong F. Nanodisc-Based Proteomics Identify Caj1 as an Hsp40 with Affinity for Phosphatidic Acid Lipids. J Proteome Res. 2021 Sep 14. doi: 10.1021/acs.jproteome.1c00503. Epub ahead of print. PMID: 34519218.

2. Navas LE, Dexter G, Liu J, Levy-Booth D, Cho M, Jang SK, Mansfield SD, Renneckar S, Mohn WW, Eltis LD. Bacterial Transformation of Aromatic Monomers in Softwood Black Liquor. Front Microbiol. 2021 Sep 10;12:735000. doi: 10.3389/fmicb.2021.735000. PMID: 34566938; PMCID: PMC8461187.

3. Khoei S, Stokes A, Kieft B, Kadota P, Hallam SJ, Eskicioglu C. Biochar amendment rapidly shifts microbial community structure with enhanced thermophilic digestion activity. Bioresour Technol. 2021 Sep 1;341:125864. doi: 10.1016/j.biortech.2021.125864. Epub ahead of print. PMID: 34523581.

4. Basher ARMA, Mclaughlin RJ, Hallam SJ. Metabolic Pathway Prediction Using Non-Negative Matrix Factorization with Improved Precision. J Comput Biol. 2021 Sep 14. doi: 10.1089/cmb.2021.0258. Epub ahead of print. PMID: 34520674.

5. Ludwig DS, Aronne LJ, Astrup A, de Cabo R, Cantley LC, Friedman MI, Heymsfield SB, Johnson JD, King JC, Krauss RM, Lieberman DE, Taubes G, Volek JS, Westman EC, Willett WC, Yancy WS, Ebbeling CB. The carbohydrate-insulin model: a physiological perspective on the obesity pandemic. Am J Clin Nutr. 2021 Sep 13:nqab270. doi: 10.1093/ajcn/nqab270. Epub ahead of print. PMID: 34515299.

6. Durrer C, McKelvey S, Singer J, Batterham AM, Johnson JD, Gudmundson K, Wortman J, Little JP. A randomized controlled trial of pharmacist-led therapeutic carbohydrate and energy restriction in type 2 diabetes. Nat Commun. 2021 Sep 10;12(1):5367. doi: 10.1038/s41467-021-25667-4. PMID: 34508090.

7. Pereira S, Cline DL, Chan M, Chai K, Yoon JS, O'Dwyer SM, Ellis CE, Glavas MM, Webber TD, Baker RK, Erener S, Covey SD, Kieffer TJ. Role of myeloid cell leptin signaling in the regulation of glucose metabolism. Sci Rep. 2021 Sep 15;11(1):18394. doi: 10.1038/s41598-021-97549-0. PMID: 34526546.

8. Persaud R, Li SC, Chao JD, Forestieri R, Donohue E, Balgi AD, Zheng X, Chao JT, Yashiroda Y, Yoshimura M, Loewen CJR, Gingras AC, Boone C, Av-Gay Y, Roberge M, Andersen RJ. Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1. Cell Chem Biol. 2021 Sep 11:S2451-9456(21)00357-3. doi: 10.1016/j.chembiol.2021.07.017. Epub ahead of print. PMID: 34520745.

9. Popadynec M, Baradaran-Heravi A, Alford B, Cameron SA, Clinch K, Mason JM, Rendle PM, Zubkova OV, Gan Z, Liu H, Rebollo O, Whitfield DM, Yan F, Roberge M, Powell DA. Reducing the Toxicity of Designer Aminoglycosides as Nonsense Mutation Readthrough Agents for Therapeutic Targets. ACS Med Chem Lett. 2021 Aug 9;12(9):1486-1492. doi: 10.1021/acsmedchemlett.1c00349. PMID: 34531957; PMCID: PMC8436412.

Sep 13, Pubcrawler Hits:

1. Ganguly P, Madonsela L, Chao JT, Loewen CJR, O'Connor TP, Verheyen EM, Allan DW. A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation. PLoS Genet. 2021 Sep 7;17(9):e1009774. doi: 10.1371/journal.pgen.1009774. Epub ahead of print. PMID: 34492006.

2. Bégin P, Callum J, Jamula E, Cook R, Heddle NM, Tinmouth A, Zeller MP, Beaudoin-Bussières G, Amorim L, Bazin R, Loftsgard KC, Carl R, Chassé M, Cushing MM, Daneman N, Devine DV, Dumaresq J, Fergusson DA, Gabe C, Glesby MJ, Li N, Liu Y, McGeer A, Robitaille N, Sachais BS, Scales DC, Schwartz L, Shehata N, Turgeon AF, Wood H, Zarychanski R, Finzi A; CONCOR-1 Study Group, Arnold DM. Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial. Nat Med. 2021 Sep 9. doi: 10.1038/s41591-021-01488-2. Epub ahead of print. PMID: 34504336.

3. Xue J, Purushotham P, Acheson JF, Ho R, Zimmer J, McFarlane C, Van Petegem F, Martone PT, Samuels AL. Functional characterization of a cellulose synthase, CtCESA1, from the marine red alga Calliarthron tuberculosum (Corallinales). J Exp Bot. 2021 Sep 10:erab414. doi: 10.1093/jxb/erab414. Epub ahead of print. PMID: 34505622.

4. Llongueras JP, Das S, De Waele J, Capulzini L, Sorgente A, Van Petegem F, Bosmans F. Biophysical Investigation of Sodium Channel Interaction with β-Subunit Variants Associated with Arrhythmias. Bioelectricity. 2020 Sep 1;2(3):269-278. doi: 10.1089/bioe.2020.0030. Epub 2020 Sep 16. PMID: 34476357; PMCID: PMC8370339.

5. Ho KYL, Khadilkar RJ, Carr RL, Tanentzapf G. A gap-junction-mediated, calcium-signaling network controls blood progenitor fate decisions in hematopoiesis. Curr Biol. 2021 Aug 31:S0960-9822(21)01131-3. doi: 10.1016/j.cub.2021.08.027. Epub ahead of print. PMID: 34480855.

Sep 6, Pubcrawler Hits:

1. Harandi-Zadeh S, Boycott C, Beetch M, Yang T, Martin BJE, Ren K, Kwasniak A, Dupuis JH, Lubecka K, Yada RY, Howe LJ, Stefanska B. Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells. Antioxidants (Basel). 2021 Jul 30;10(8):1232. doi: 10.3390/antiox10081232. PMID: 34439480; PMCID: PMC8388921.

2. Workman SD, Day J, Farha MA, El Zahed SS, Bon C, Brown ED, Organ MG, Strynadka NCJ. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 2. doi: 10.1021/acs.jmedchem.1c00941. Epub ahead of print. PMID: 34473495.

3. Rathinaswamy MK, Dalwadi U, Fleming KD, Adams C, Stariha JTB, Pardon E, Baek M, Vadas O, DiMaio F, Steyaert J, Hansen SD, Yip CK, Burke JE. Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation. Sci Adv. 2021 Aug 27;7(35):eabj4282. doi: 10.1126/sciadv.abj4282. PMID: 34452907.

4. Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T, Juhász G, Karantza V, Kraft C, Kroemer G, Ktistakis NT, Kumar S, Lopez-Otin C, Macleod KF, Madeo F, Martinez J, Meléndez A, Mizushima N, Münz C, Penninger JM, Perera RM, Piacentini M, Reggiori F, Rubinsztein DC, Ryan KM, Sadoshima J, Santambrogio L, Scorrano L, Simon HU, Simon AK, Simonsen A, Stolz A, Tavernarakis N, Tooze SA, Yoshimori T, Yuan J, Yue Z, Zhong Q, Galluzzi L, Pietrocola F. Autophagy in major human diseases. EMBO J. 2021 Aug 30:e108863. doi: 10.15252/embj.2021108863. Epub ahead of print. PMID: 34459017.

5. Berger CS, Laroche J, Maaroufi H, Martin H, Moon KM, Landry CR, Foster LJ, Aubin-Horth N. The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions. Parasit Vectors. 2021 Aug 28;14(1):436. doi: 10.1186/s13071-021-04933-w. PMID: 34454597; PMCID: PMC8400842.

Aug 30, Pubcrawler Hits:

1. Kizhakkedathu JN, Conway EM. Biomaterial and cellular implants:foreign surfaces where immunity and coagulation meet. Blood. 2021 Aug 20:blood.2020007209. doi: 10.1182/blood.2020007209. Epub ahead of print. PMID: 34415324.

2. Round JW, Robeck LD, Eltis LD. An Integrative Toolbox for Synthetic Biology in Rhodococcus. ACS Synth Biol. 2021 Aug 24. doi: 10.1021/acssynbio.1c00292. Epub ahead of print. PMID: 34428025.

3. Palia P, Adams A, Sriram A, Vogl AW. Cortactin knockdown results in disruption of basal TBCs and alters turnover of Sertoli cell ESs in R. norvegicus. Biol Reprod. 2021 Aug 23:ioab161. doi: 10.1093/biolre/ioab161. Epub ahead of print. PMID: 34426822.

4. Tropini C. How the Physical Environment Shapes the Microbiota. mSystems. 2021 Aug 24:e0067521. doi: 10.1128/mSystems.00675-21. Epub ahead of print. PMID: 34427510.

Aug 23, Pubcrawler Hits:

1. Stanley M, Ghosh B, Weiss ZF, Christiaanse J, Gordon MD. Mechanisms of lactic acid gustatory attraction in Drosophila. Curr Biol. 2021 Aug 23;31(16):3525-3537.e6. doi: 10.1016/j.cub.2021.06.005. Epub 2021 Jun 30. PMID: 34197729.

2. Andriessen VC, Lightbourne M, Flippo C, Faucz FR, Delaney A, Hannah-Shmouni F, Hammond GL, Stratakis CA. Homozygous SHBG Variant (rs6258) Linked to Gonadotropin-Independent Precocious Puberty in a Young Girl. J Endocr Soc. 2021 Jul 19;5(10):bvab125. doi: 10.1210/jendso/bvab125. PMID: 34405127; PMCID: PMC8364343.

3. Scalzo RL, Foright RM, Hull SE, Knaub LA, Johnson-Murguia S, Kinanee F, Kaplan J, Houck JA, Johnson G, Sharp RR, Gillen AE, Jones KL, Zhang AMY, Johnson JD, MacLean PS, Reusch JEB, Wright-Hobart S, Wellberg EA. Breast cancer endocrine therapy promotes weight gain with distinct adipose tissue effects in lean and obese female mice. Endocrinology. 2021 Aug 19:bqab174. doi: 10.1210/endocr/bqab174. Epub ahead of print. PMID: 34410380.

4. Erwin SR, Bristow BN, Sullivan KE, Kendrick RM, Marriott B, Wang L, Clements J, Lemire AL, Jackson J, Cembrowski MS. Spatially patterned excitatory neuron subtypes and projections of the claustrum. Elife. 2021 Aug 16;10:e68967. doi: 10.7554/eLife.68967. PMID: 34397382; PMCID: PMC8367382.

Aug 16, Pubcrawler Hits:

1. Iworima DG, Rieck S, Kieffer TJ. Process parameter development for the scaled generation of stem cell-derived pancreatic endocrine cells. Stem Cells Transl Med. 2021 Aug 13. doi: 10.1002/sctm.21-0161. Epub ahead of print. PMID: 34387389.

2. Siren EMJ, Luo HD, Tam F, Montgomery A, Enns W, Moon H, Sim L, Rey K, Guan Q, Wang JJ, Wardell CM, Monajemi M, Mojibian M, Levings MK, Zhang ZJ, Du C, Withers SG, Choy JC, Kizhakkedathu JN. Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers. Nat Biomed Eng. 2021 Aug 9. doi: 10.1038/s41551-021-00777-y. Epub ahead of print. PMID: 34373602.

3. Kurashina M, Wang J, Lin J, Lee KK, Johal A, Mizumoto K. Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans. Elife. 2021 Aug 13;10:e66011. doi: 10.7554/eLife.66011. PMID: 34388088.

4. Brotto LA, Zdaniuk B, Chivers ML, Jabs F, Grabovac A, Lalumière ML, Weinberg J, Schonert-Reichl KA, Basson R. A randomized trial comparing group mindfulness-based cognitive therapy with group supportive sex education and therapy for the treatment of female sexual interest/arousal disorder. J Consult Clin Psychol. 2021 Jul;89(7):626-639. doi: 10.1037/ccp0000661. PMID: 34383535.

5. Hoffmann D, Mereiter S, Jin Oh Y, Monteil V, Elder E, Zhu R, Canena D, Hain L, Laurent E, Grünwald-Gruber C, Klausberger M, Jonsson G, Kellner MJ, Novatchkova M, Ticevic M, Chabloz A, Wirnsberger G, Hagelkruys A, Altmann F, Mach L, Stadlmann J, Oostenbrink C, Mirazimi A, Hinterdorfer P, Penninger JM. Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites. EMBO J. 2021 Aug 10:e108375. doi: 10.15252/embj.2021108375. Epub ahead of print. PMID: 34375000.

6. McAfee A, Tarpy DR, Foster LJ. Queen honey bees exhibit variable resilience to temperature stress. PLoS One. 2021 Aug 11;16(8):e0255381. doi: 10.1371/journal.pone.0255381. PMID: 34379669; PMCID: PMC8357134.

Aug 9, Pubcrawler Hits:

1. van der Meel R, Chen S, Zaifman J, Kulkarni JA, Zhang XRS, Tam YK, Bally MB, Schiffelers RM, Ciufolini MA, Cullis PR, Tam YYC. Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery. Small. 2021 Aug 1:e2103025. doi: 10.1002/smll.202103025. Epub ahead of print. PMID: 34337865.

2. Zhao X, Khatir B, Mirshahidi K, Yu K, Kizhakkedathu JN, Golovin K. Macroscopic Evidence of the Liquidlike Nature of Nanoscale Polydimethylsiloxane Brushes. ACS Nano. 2021 Aug 2. doi: 10.1021/acsnano.1c04386. Epub ahead of print. PMID: 34339162.

3. Rathinaswamy MK, Fleming KD, Dalwadi U, Pardon E, Harris NJ, Yip CK, Steyaert J, Burke JE. HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases. Structure. 2021 Jul 30:S0969-2126(21)00252-5. doi: 10.1016/j.str.2021.07.002. Epub ahead of print. PMID: 34348129.

Aug 2, Pubcrawler Hits:

1. Yip D, Accili E. Kinetic modelling of voltage-dependent gating in funny channels. Prog Biophys Mol Biol. 2021 Jul 23:S0079-6107(21)00090-0. doi: 10.1016/j.pbiomolbio.2021.07.009. Epub ahead of print. PMID: 34310984.

2. Wolf ME, Hinchen DJ, DuBois JL, McGeehan JE, Eltis LD. Cytochromes P450 in the biocatalytic valorization of lignin. Curr Opin Biotechnol. 2021 Jul 21;73:43-50. doi: 10.1016/j.copbio.2021.06.022. Epub ahead of print. PMID: 34303185.

3. Wardman JF, Rahfeld P, Liu F, Morgan-Lang C, Sim L, Hallam SJ, Withers SG. Discovery and Development of Promiscuous O-Glycan Hydrolases for Removal of Intact Sialyl T-Antigen. ACS Chem Biol. 2021 Jul 26. doi: 10.1021/acschembio.1c00316. Epub ahead of print. PMID: 34309358.

4. Johnson JD. On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes. Diabetologia. 2021 Jul 22. doi: 10.1007/s00125-021-05505-4. Epub ahead of print. PMID: 34296322.

5. Yu K, Alzahrani A, Khoddami S, Cheng JTJ, Mei Y, Gill A, Luo HD, Haney EF, Hilpert K, Hancock REW, Lange D, Kizhakkedathu JN. Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background. ACS Appl Mater Interfaces. 2021 Jul 30. doi: 10.1021/acsami.1c07515. Epub ahead of print. PMID: 34328312.

6. Amenyogbe N, Adu-Gyasi D, Enuameh Y, Asante KP, Konadu DG, Kaali S, Dosoo D, Panigrahi P, Kollmann TR, Mohn WW, Owusu-Agyei S. Bacterial and Fungal Gut Community Dynamics Over the First 5 Years of Life in Predominantly Rural Communities in Ghana. Front Microbiol. 2021 Jul 6;12:664407. doi: 10.3389/fmicb.2021.664407. PMID: 34295315; PMCID: PMC8290483.

7. Ng KM, Tropini C. Visualization of Gut Microbiota-host Interactions via Fluorescence In Situ Hybridization, Lectin Staining, and Imaging. J Vis Exp. 2021 Jul 9;(173). doi: 10.3791/62646. PMID: 34309601.

8. McAfee A, Milone JP, Metz B, McDermott E, Foster LJ, Tarpy DR. Honey bee queen health is unaffected by contact exposure to pesticides commonly found in beeswax. Sci Rep. 2021 Jul 26;11(1):15151. doi: 10.1038/s41598-021-94554-1. PMID: 34312437; PMCID: PMC8313582.

July 26, Pubcrawler Hits:

1. Hoiland RL, Ainslie PN, Wellington CL, Cooper J, Stukas S, Thiara S, Foster D, Fergusson N, Conway EM, Menon DK, Gooderham PA, Hirsch-Reinshagen V, Griesdale D, Sekhon M. Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post-Cardiac Arrest. Circ Res. 2021 Jul 21. doi: 10.1161/CIRCRESAHA.121.319157. Epub ahead of print. PMID: 34287000.

2. Schubert P, Chen Z, Bhakta V, Culibrk B, Wambolt R, Sheffield WP, Devine DV, McTaggart K. Cold-stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality. Transfusion. 2021 Jul;61 Suppl 1:S131-S143. doi: 10.1111/trf.16540. PMID: 34269454.

3. Ramzy A, Kieffer TJ. Altered islet prohormone processing: A cause or consequence of diabetes? Physiol Rev. 2021 Jul 19. doi: 10.1152/physrev.00008.2021. Epub ahead of print. PMID: 34280055.

4. Woll KA, Van Petegem F. Calcium Release Channels: Structure and Function of IP3 Receptors and Ryanodine Receptors. Physiol Rev. 2021 Jul 19. doi: 10.1152/physrev.00033.2020. Epub ahead of print. PMID: 34280054.

5. Baek M, DiMaio F, Anishchenko I, Dauparas J, Ovchinnikov S, Lee GR, Wang J, Cong Q, Kinch LN, Schaeffer RD, Millán C, Park H, Adams C, Glassman CR, DeGiovanni A, Pereira JH, Rodrigues AV, van Dijk AA, Ebrecht AC, Opperman DJ, Sagmeister T, Buhlheller C, Pavkov-Keller T, Rathinaswamy MK, Dalwadi U, Yip CK, Burke JE, Garcia KC, Grishin NV, Adams PD, Read RJ, Baker D. Accurate prediction of protein structures and interactions using a three-track neural network. Science. 2021 Jul 15:eabj8754. doi: 10.1126/science.abj8754. Epub ahead of print. PMID: 34282049.

6. Morisaki I, Shiraishi H, Fujinami H, Shimizu N, Hikida T, Arai Y, Kobayashi T, Hanada R, Penninger JM, Fujiki M, Hanada T. Modeling a human CLP1 mutation in mouse identifies an accumulation of tyrosine pre-tRNA fragments causing pontocerebellar hypoplasia type 10. Biochem Biophys Res Commun. 2021 Jul 14;570:60-66. doi: 10.1016/j.bbrc.2021.07.036. Epub ahead of print. PMID: 34273619.

July 19, Pubcrawler Hits:

1. Deretic N, Bolger-Munro M, Choi K, Abraham L, Gold MR. The Actin-Disassembly Protein Glia Maturation Factor γ Enhances Actin Remodeling and B Cell Antigen Receptor Signaling at the Immune Synapse. Front Cell Dev Biol. 2021 Jul 9;9:647063. doi: 10.3389/fcell.2021.647063. PMID: 34336818; PMCID: PMC8318000.

2. Kolic J, Johnson JD. Promises and pitfalls of beta cell-replacement therapies. Nat Metab. 2021 Jul 12. doi: 10.1038/s42255-021-00433-4. Epub ahead of print. PMID: 34253907.

3. Wong AKO, Young BP, Loewen CJR. Ist2 recruits the lipid transporters Osh6/7 to ER-PM contacts to maintain phospholipid metabolism. J Cell Biol. 2021 Sep 6;220(9):e201910161. doi: 10.1083/jcb.201910161. Epub 2021 Jul 14. PMID: 34259806.

4. Feller FM, Wöhlbrand L, Holert J, Schnaars V, Elsner L, Mohn WW, Rabus R, Philipp B. Proteome, bioinformatic and functional analyses reveal a distinct and conserved metabolic pathway for bile salt degradation in the Sphingomonadaceae. Appl Environ Microbiol. 2021 Jul 14:AEM0098721. doi: 10.1128/AEM.00987-21. Epub ahead of print. PMID: 34260303.

July 12, Pubcrawler Hits:

1. Xia J, Accili EA. Regulation of sinoatrial funny channels by cyclic nucleotides: From adrenaline and IK2 to direct binding of ligands to protein subunits. Prog Biophys Mol Biol. 2021 Jul 5:S0079-6107(21)00070-5. doi: 10.1016/j.pbiomolbio.2021.06.010. Epub ahead of print. PMID: 34237319.

2. Beetch M, Boycott C, Harandi-Zadeh S, Yang T, Martin BJE, Dixon-McDougall T, Ren K, Gacad A, Dupuis JH, Ullmer M, Lubecka K, Yada RY, Brown CJ, Howe LJ, Stefanska B. Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells. J Nutr Biochem. 2021 Jul 6:108815. doi: 10.1016/j.jnutbio.2021.108815. Epub ahead of print. PMID: 34242723.

3. Glavas MM, Hui Q, Miao I, Yang F, Erener S, Prentice KJ, Wheeler MB, Kieffer TJ. Early overnutrition in male mice negates metabolic benefits of a diet high in monounsaturated and omega-3 fats. Sci Rep. 2021 Jul 7;11(1):14032. doi: 10.1038/s41598-021-93409-z. PMID: 34234216; PMCID: PMC8263808.

4. Harris NJ, Jenkins ML, Dalwadi U, Fleming KD, Nam SE, Parsons MAH, Yip CK, Burke JE. Biochemical insight into novel Rab-GEF activity of the mammalian TRAPPIII complex. J Mol Biol. 2021 Jul 3:167145. doi: 10.1016/j.jmb.2021.167145. Epub ahead of print. PMID: 34229011.

5. Teves S. Embracing my roots. Science. 2021 Jul 2;373(6550):126. doi: 10.1126/science.373.6550.126. PMID: 34210889.

6. Bennet TJ, Randhawa A, Hua J, Cheung KC. Airway-On-A-Chip: Designs and Applications for Lung Repair and Disease. Cells. 2021 Jun 26;10(7):1602. doi: 10.3390/cells10071602. PMID: 34206722.

7. Skinnider MA, Foster LJ. Meta-analysis defines principles for the design and analysis of co-fractionation mass spectrometry experiments. Nat Methods. 2021 Jul;18(7):806-815. doi: 10.1038/s41592-021-01194-4. Epub 2021 Jul 1. PMID: 34211188.

8. Squair JW, Skinnider MA, Gautier M, Foster LJ, Courtine G. Prioritization of cell types responsive to biological perturbations in single-cell data with Augur. Nat Protoc. 2021 Jun 25. doi: 10.1038/s41596-021-00561-x. Epub ahead of print. PMID: 34172974.

9. Skinnider MA, Rogalski J, Tigchelaar S, Manouchehri N, Prudova A, Jackson AM, Nielsen K, Jeong J, Chaudhary S, Shortt K, Gallagher-Kurtzke Y, So K, Fong A, Gupta R, Okon EB, Rizzuto MA, Dong K, Streijger F, Belanger L, Ritchie L, Tsang A, Christie S, Mac-Thiong JM, Bailey C, Ailon T, Charest-Morin R, Dea N, Wilson JR, Dhall S, Paquette S, Street J, Fisher CG, Dvorak MF, Shannon C, Borchers C, Balshaw R, Foster LJ, Kwon BK. Proteomic Portraits Reveal Evolutionarily Conserved and Divergent Responses to Spinal Cord Injury. Mol Cell Proteomics. 2021 Jun 12;20:100096. doi: 10.1016/j.mcpro.2021.100096. Epub ahead of print. PMID: 34129941.

July 5, Pubcrawler Hits:

1. Balaton BP, Brown CJ. Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation. Epigenetics Chromatin. 2021 Jun 29;14(1):30. doi: 10.1186/s13072-021-00404-9. PMID: 34187555; PMCID: PMC8244145.

2. Skinnider MA, Scott NE, Prudova A, Kerr CH, Stoynov N, Stacey RG, Chan QWT, Rattray D, Gsponer J, Foster LJ. An atlas of protein-protein interactions across mouse tissues. Cell. 2021 Jun 22:S0092-8674(21)00704-2. doi: 10.1016/j.cell.2021.06.003. Epub ahead of print. PMID: 34214469.

June 28, Pubcrawler Hits:

1. Yong J, Johnson JD, Arvan P, Han J, Kaufman RJ. Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus. Nat Rev Endocrinol. 2021 Jun 23. doi: 10.1038/s41574-021-00510-4. Epub ahead of print. PMID: 34163039.

2. Satishkumar N, Alexander JAN, Poon R, Buggeln E, Argudín MA, Strynadka NCJ, Chatterjee SS. PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus. J Antimicrob Chemother. 2021 Jun 21:dkab201. doi: 10.1093/jac/dkab201. Epub ahead of print. PMID: 34151961.

June 21, Pubcrawler Hits:

1. Jun D, Zhang S, Grzędowski AJ, Mahey A, Beatty JT, Bizzotto D. Correlating structural assemblies of photosynthetic reaction centers on a gold electrode and the photocurrent - potential response. iScience. 2021 May 4;24(5):102500. doi: 10.1016/j.isci.2021.102500. PMID: 34113832; PMCID: PMC8170006.

2. Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV. Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles. Transfusion. 2021 Jun 14. doi: 10.1111/trf.16542. Epub ahead of print. PMID: 34121199.

3. Karahan G, Chan D, Shirane K, McClatchie T, Janssen S, Baltz JM, Lorincz M, Trasler J. Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations. Development. 2021 Jun 15:dev.199492. doi: 10.1242/dev.199492. Epub ahead of print. PMID: 34128976.

4. Rufenach B, Van Petegem F. Structure and function of STAC proteins: calcium channel modulators and critical components of muscle excitation-contraction coupling. J Biol Chem. 2021 Jun 12:100874. doi: 10.1016/j.jbc.2021.100874. Epub ahead of print. PMID: 34129875.

5. Rens C, Shapira T, Peña-Diaz S, Chao JD, Pfeifer T, Av-Gay Y. Apoptosis assessment in high-content and high-throughput screening assays. Biotechniques. 2021 Jun;70(6):309-318. doi: 10.2144/btn-2020-0164. Epub 2021 Jun 11. PMID: 34114488.

6. Onji M, Werschler N, Penninger J. A critical relationship between bone and fat: the role of bone marrow adipose-derived RANKL in bone metabolism. EMBO Rep. 2021 Jun 13:e52986. doi: 10.15252/embr.202152986. Epub ahead of print. PMID: 34121307.

June 14, Pubcrawler Hits:

1. Tam A, Leclair P, Li LV, Yang CX, Li X, Witzigmann D, Kulkarni JA, Hackett TL, Dorscheid DR, Singhera GK, Hogg JC, Cullis PR, Sin DD, Lim CJ. FAM13A as potential therapeutic target in modulating TGF-beta-induced airway tissue remodeling in COPD. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 9. doi: 10.1152/ajplung.00477.2020. Epub ahead of print. PMID: 34105356.

2. Kieft K, Zhou Z, Anderson RE, Buchan A, Campbell BJ, Hallam SJ, Hess M, Sullivan MB, Walsh DA, Roux S, Anantharaman K. Ecology of inorganic sulfur auxiliary metabolism in widespread bacteriophages. Nat Commun. 2021 Jun 9;12(1):3503. doi: 10.1038/s41467-021-23698-5. PMID: 34108477.

3. Abbasi U, Abbina S, Gill A, Takuechi LE, Kizhakkedathu JN. Role of Iron in the Molecular Pathogenesis of Diseases and Therapeutic Opportunities. ACS Chem Biol. 2021 Jun 9. doi: 10.1021/acschembio.1c00122. Epub ahead of print. PMID: 34102834.

4. Chen J, Debebe A, Zeng N, Kopp J, He L, Sander M, Stiles BL. Transformation of SOX9+ cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma. Sci Rep. 2021 Jun 3;11(1):11823. doi: 10.1038/s41598-021-90958-1. PMID: 34083580; PMCID: PMC8175600.

June 7, Pubcrawler Hits:

1. Inkster AM, Yuan V, Konwar C, Matthews AM, Brown CJ, Robinson WP. A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta. Biol Sex Differ. 2021 May 27;12(1):38. doi: 10.1186/s13293-021-00381-4. PMID: 34044884; PMCID: PMC8162041.

2. Kulkarni JA, Witzigmann D, Thomson SB, Chen S, Leavitt BR, Cullis PR, van der Meel R. The current landscape of nucleic acid therapeutics. Nat Nanotechnol. 2021 May 31. doi: 10.1038/s41565-021-00898-0. Epub ahead of print. PMID: 34059811.

3. Mouat IC, Morse ZJ, Shanina I, Brown KL, Horwitz MS. Latent gammaherpesvirus exacerbates arthritis through modification of age-associated B cells. Elife. 2021 Jun 3;10:e67024. doi: 10.7554/eLife.67024. Epub ahead of print. PMID: 34080972.

4. Wang S, Flibotte S, Camunas-Soler J, MacDonald PE, Johnson JD. A New Hypothesis for Type 1 Diabetes Risk: The At-Risk Allele at rs3842753 Associates With Increased Beta-cell INS Messenger RNA in a Meta-Analysis of Single-Cell RNA-Sequencing Data. Can J Diabetes. 2021 Apr 3:S1499-2671(21)00081-2. doi: 10.1016/j.jcjd.2021.03.007. Epub ahead of print. PMID: 34052132.

May 31, Pubcrawler Hits:

1. Roux S, Paul BG, Bagby SC, Nayfach S, Allen MA, Attwood G, Cavicchioli R, Chistoserdova L, Gruninger RJ, Hallam SJ, Hernandez ME, Hess M, Liu WT, McAllister TA, O'Malley MA, Peng X, Rich VI, Saleska SR, Eloe-Fadrosh EA. Ecology and molecular targets of hypermutation in the global microbiome. Nat Commun. 2021 May 24;12(1):3076. doi: 10.1038/s41467-021-23402-7. PMID: 34031405.

May 24, Pubcrawler Hits:

1. Muria A, Musso PY, Durrieu M, Portugal FR, Ronsin B, Gordon MD, Jeanson R, Isabel G. Social facilitation of long-lasting memory is mediated by CO2 in Drosophila. Curr Biol. 2021 May 24;31(10):2065-2074.e5. doi: 10.1016/j.cub.2021.02.044. Epub 2021 Mar 18. PMID: 33740428.

2. Heda P, Alalola B, Almeida FR, Kim H, Peres BU, Pliska BT. Long-term periodontal changes associated with oral appliance treatment of obstructive sleep apnea. J Clin Sleep Med. 2021 May 14. doi: 10.5664/jcsm.9358. Epub ahead of print. PMID: 33985648.

3. Alcaraz LB, Mallavialle A, David T, Derocq D, Delolme F, Dieryckx C, Mollevi C, Boissière-Michot F, Simony-Lafontaine J, Du Manoir S, Huesgen PF, Overall CM, Tartare-Deckert S, Jacot W, Chardès T, Guiu S, Roger P, Reinheckel T, Moali C, Liaudet-Coopman E. A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment. Theranostics. 2021 Apr 15;11(13):6173-6192. doi: 10.7150/thno.58254. PMID: 33995652; PMCID: PMC8120228.

4. Jain N, Tamura K, Déjean G, Van Petegem F, Brumer H. Orthogonal Active-Site Labels for Mixed-Linkage endo-β-Glucanases. ACS Chem Biol. 2021 May 14. doi: 10.1021/acschembio.1c00063. Epub ahead of print. PMID: 33988963.

5. Brink KS, Henríquez JI, Grieco TM, Martin Del Campo JR, Fu K, Richman JM. Tooth Removal in the Leopard Gecko and the de novo Formation of Replacement Teeth. Front Physiol. 2021 May 4;12:576816. doi: 10.3389/fphys.2021.576816. PMID: 34012403; PMCID: PMC8126719.

6. Caveney NA, Workman SD, Yan R, Atkinson CE, Yu Z, Strynadka NCJ. CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution. Nat Commun. 2021 May 13;12(1):2775. doi: 10.1038/s41467-021-23063-6. PMID: 33986273; PMCID: PMC8119973.

7. Ajoolabady A, Aslkhodapasandhokmabad H, Libby P, Tuomilehto J, Lip GYH, Penninger JM, Richardson DR, Tang D, Zhou H, Wang S, Klionsky DJ, Kroemer G, Ren J. Ferritinophagy and ferroptosis in the management of metabolic diseases. Trends Endocrinol Metab. 2021 May 15:S1043-2760(21)00095-3. doi: 10.1016/j.tem.2021.04.010. Epub ahead of print. PMID: 34006412.

May 17, Pubcrawler Hits:

1. Siren EMJ, Luo HD, Bajaj S, MacKenzie J, Daneshi M, Martinez DM, Conway EM, Cheung KC, Kizhakkedathu JN. An improved in vitro model for studying the structural and functional properties of the endothelial glycocalyx in arteries, capillaries and veins. FASEB J. 2021 Jun;35(6):e21643. doi: 10.1096/fj.201802376RRRR. PMID: 33977574.

2. Devine DV. Rethinking platelet transfusion practices. Blood. 2021 May 13;137(19):2576-2577. doi: 10.1182/blood.2021011269. PMID: 33983425.

3. Vardaki MZ, Schulze HG, Serrano K, Blades MW, Devine DV, Turner RFB. Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy. Transfusion. 2021 May 10. doi: 10.1111/trf.16417. Epub ahead of print. PMID: 33969894.

4. Kuatsjah E, Chan ACK, Katahira R, Haugen SJ, Beckham GT, Murphy MEP, Eltis LD. Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6. J Biol Chem. 2021 May 6:100758. doi: 10.1016/j.jbc.2021.100758. Epub ahead of print. PMID: 33965373.

May 10, Pubcrawler Hits:

1. Bégin P, Callum J, Heddle NM, Cook R, Zeller MP, Tinmouth A, Fergusson DA, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitalle N, Bazin R, Shehata N, Finzi A, McGeer A, Scales DC, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Sachais BS, Loftsgard KC, Jamula E, Carruthers J, Duncan J, Lucier K, Li N, Liu Y, Armali C, Kron A, Modi D, Auclair MC, Cerro S, Avram M, Arnold DM. Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial. Trials. 2021 May 4;22(1):323. doi: 10.1186/s13063-021-05235-3. PMID: 33947446; PMCID: PMC8094980.

2. Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohoněk M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N. International Forum on Walking Blood Bank Programmes: Responses. Vox Sang. 2021 May 3. doi: 10.1111/vox.13102. Epub ahead of print. PMID: 33939177.

3. Rodriguez-Calvo T, Johnson JD, Overbergh L, Dunne JL. Neoepitopes in Type 1 Diabetes: Etiological Insights, Biomarkers and Therapeutic Targets. Front Immunol. 2021 Apr 19;12:667989. doi: 10.3389/fimmu.2021.667989. PMID: 33953728; PMCID: PMC8089389.

4. Skiba NP, Cady MA, Molday L, Han JYS, Lewis TR, Spencer WJ, Thompson WJ, Hiles S, Philp NJ, Molday RS, Arshavsky VY. TMEM67, TMEM237 and embigin in the complex with lactate transporter MCT1 are unique components of the photoreceptor outer segment plasma membrane. Mol Cell Proteomics. 2021 Apr 29:100088. doi: 10.1016/j.mcpro.2021.100088. Epub ahead of print. PMID: 33933680.

5. Hosseini-Farahabadi S, Baradaran-Heravi A, Zimmerman C, Choi K, Flibotte S, Roberge M. Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough. PLoS Biol. 2021 May 3;19(5):e3001221. doi: 10.1371/journal.pbio.3001221. Epub ahead of print. PMID: 33939688.

6. Av-Gay Y, Mori G, Pasca MR. Editorial: New Approaches Against Drug-Resistant M. tuberculosis. Front Microbiol. 2021 Apr 15;12:681420. doi: 10.3389/fmicb.2021.681420. PMID: 33936024; PMCID: PMC8081967.

May 3, Pubcrawler Hits:

1. Hadjesfandiari N, Khorshidfar M, Devine DV. Current Understanding of the Relationship between Blood Donor Variability and Blood Component Quality. Int J Mol Sci. 2021 Apr 11;22(8):3943. doi: 10.3390/ijms22083943. PMID: 33920459; PMCID: PMC8069744.

2. Bolger-Munro M, Choi K, Cheung F, Liu YT, Dang-Lawson M, Deretic N, Keane C, Gold MR. The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse. Front Cell Dev Biol. 2021 Apr 13;9:649433. doi: 10.3389/fcell.2021.649433. PMID: 33928084; PMCID: PMC8076898.

3. Lee W, Zernant J, Nagasaki T, Molday LL, Su PY, Fishman GA, Tsang SH, Molday RS, Allikmets R. Cis-acting modifiers in the ABCA4 locus contribute to the penetrance of the major disease-causing variant in Stargardt disease. Hum Mol Genet. 2021 Apr 28:ddab122. doi: 10.1093/hmg/ddab122. Epub ahead of print. PMID: 33909047.

4. Scala M, Efthymiou S, Sultan T, De Waele J, Panciroli M, Salpietro V, Maroofian R, Striano P, Van Petegem F, Houlden H, Bosmans F. Homozygous SCN1B variants causing early infantile epileptic encephalopathy 52 affect voltage-gated sodium channel function. Epilepsia. 2021 Apr 26. doi: 10.1111/epi.16913. Epub ahead of print. PMID: 33901312.

5. Muñoz-Muñoz L, Shoen C, Sweet G, Vitoria A, Bull TJ, Cynamon M, Thompson CJ, Ramón-García S. Repurposing Avermectins and Milbemycins against Mycobacteroides abscessus and Other Nontuberculous Mycobacteria. Antibiotics (Basel). 2021 Apr 3;10(4):381. doi: 10.3390/antibiotics10040381. PMID: 33916775; PMCID: PMC8066277.

6. Asanović I, Strandback E, Kroupova A, Pasajlic D, Meinhart A, Tsung-Pin P, Djokovic N, Anrather D, Schuetz T, Suskiewicz MJ, Sillamaa S, Köcher T, Beveridge R, Nikolic K, Schleiffer A, Jinek M, Hartl M, Clausen T, Penninger J, Macheroux P, Weitzer S, Martinez J. The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response. Mol Cell. 2021 Apr 23:S1097-2765(21)00312-9. doi: 10.1016/j.molcel.2021.04.007. Epub ahead of print. PMID: 33930333.

7. Cameron T, Bennet T, Rowe EM, Anwer M, Wellington CL, Cheung KC. Review of Design Considerations for Brain-on-a-Chip Models. Micromachines (Basel). 2021 Apr 15;12(4):441. doi: 10.3390/mi12040441. PMID: 33921018; PMCID: PMC8071412.

Apr 26, Pubcrawler Hits:

1. Chander N, Morstein J, Bolten JS, Shemet A, Cullis PR, Trauner D, Witzigmann D. Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release. Small. 2021 Apr 20:e2008198. doi: 10.1002/smll.202008198. Epub ahead of print. PMID: 33880882.

2. Chao JT, Roskelley CD, Loewen CJR. MAPS: machine-assisted phenotype scoring enables rapid functional assessment of genetic variants by high-content microscopy. BMC Bioinformatics. 2021 Apr 20;22(1):202. doi: 10.1186/s12859-021-04117-4. PMID: 33879063; PMCID: PMC8056608.

3. Lu HY, Sharma M, Sharma AA, Lacson A, Szpurko A, Luider J, Dharmani-Khan P, Shameli A, Bell PA, Guilcher GMT, Lewis VA, Vasquez MR, Desai S, McGonigle L, Murguia-Favela L, Wright NAM, Sergi C, Wine E, Overall CM, Suresh S, Turvey SE. Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency. J Allergy Clin Immunol. 2021 Apr 16:S0091-6749(21)00612-6. doi: 10.1016/j.jaci.2021.04.006. Epub ahead of print. PMID: 33872653.

Apr 19, Pubcrawler Hits:

1. Friese A, Bauer K, Glombitza C, Ordoñez L, Ariztegui D, Heuer VB, Vuillemin A, Henny C, Nomosatryo S, Simister R, Wagner D, Bijaksana S, Vogel H, Melles M, Russell JM, Crowe SA, Kallmeyer J. Organic matter mineralization in modern and ancient ferruginous sediments. Nat Commun. 2021 Apr 13;12(1):2216. doi: 10.1038/s41467-021-22453-0. PMID: 33850127.

Apr 12, Pubcrawler Hits:

1. Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM. CD248 enhances tissue factor (TF) procoagulant function, promoting arterial and venous thrombosis in mouse models. J Thromb Haemost. 2021 Apr 8. doi: 10.1111/jth.15338. Epub ahead of print. PMID: 33830628.

2. Crowe SA, Simister RL, Spence JS, Kenward PA, Van Slyke AC, Lennox P, Carr N. Microbial community compositions in breast implant biofilms associated with contracted capsules. PLoS One. 2021 Apr 8;16(4):e0249261. doi: 10.1371/journal.pone.0249261. PMID: 33831065.

3. Wang X, Vlok M, Flibotte S, Jan E. Resurrection of a Viral Internal Ribosome Entry Site from a 700 Year Old Ancient Northwest Territories Cripavirus. Viruses. 2021 Mar 17;13(3):493. doi: 10.3390/v13030493. PMID: 33802878; PMCID: PMC8002689.

4. Balboa D, Iworima DG, Kieffer TJ. Human Pluripotent Stem Cells to Model Islet Defects in Diabetes. Front Endocrinol (Lausanne). 2021 Mar 22;12:642152. doi: 10.3389/fendo.2021.642152. PMID: 33828531; PMCID: PMC8020750.

5. Li FKK, Gale RT, Petrotchenko EV, Borchers CH, Brown ED, Strynadka NCJ. Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. J Struct Biol. 2021 Apr 2:107733. doi: 10.1016/j.jsb.2021.107733. Epub ahead of print. PMID: 33819634.

6. Rankine-Wilson LI, Shapira T, Sao Emani C, Av-Gay Y. From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis. Microbiology (Reading). 2021 Apr;167(4). doi: 10.1099/mic.0.001041. PMID: 33826491.

7. Ajoolabady A, Wang S, Kroemer G, Penninger JM, Uversky VN, Pratico D, Henninger N, Reiter RJ, Bruno A, Joshipura K, Aslkhodapasandhokmabad H, Klionsky DJ, Ren J. Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics. Pharmacol Ther. 2021 Apr 3:107848. doi: 10.1016/j.pharmthera.2021.107848. Epub ahead of print. PMID: 33823204.

Apr 5, Pubcrawler Hits:

1. Vogler J, Böttger R, Al Fayez N, Zhang W, Qin Z, Hohenwarter L, Chao PH, Rouhollahi E, Bilal N, Chen N, Lee B, Chen C, Wilkinson B, Kieffer TJ, Kulkarni JA, Cullis PR, Witzigmann D, Li SD. Altering the intra-liver distribution of phospholipid-free small unilamellar vesicles using temperature-dependent size-tunability. J Control Release. 2021 Mar 23;333:151-161. doi: 10.1016/j.jconrel.2021.03.025. Epub ahead of print. PMID: 33771624.

2. Zhao HW, Serrano K, Stefanoni D, D'Alessandro A, Devine DVIn Vitro Characterization and Metabolomic Analysis of Cold-Stored Platelets. J Proteome Res. 2021 Mar 29. doi: 10.1021/acs.jproteome.0c00792. Epub ahead of print. PMID: 33780259.

3. Zhang AMY, Wellberg EA, Kopp JL, Johnson JD. Hyperinsulinemia in Obesity, Inflammation, and Cancer. Diabetes Metab J. 2021 Mar 29. doi: 10.4093/dmj.2020.0250. Epub ahead of print. PMID: 33775061.

4. Fettig NM, Osborne LC. Direct and indirect effects of microbiota-derived metabolites on neuroinflammation in multiple sclerosis. Microbes Infect. 2021 Mar 25:104814. doi: 10.1016/j.micinf.2021.104814. Epub ahead of print. PMID: 33775860.

5. Millington JW, Brownrigg GP, Basner-Collins PJ, Sun Z, Rideout EJ. Genetic manipulation of insulin/insulin-like growth factor signaling pathway activity has sex-biased effects on Drosophila body size. G3 (Bethesda). 2021 Jan 11:jkaa067. doi: 10.1093/g3journal/jkaa067. Epub ahead of print. PMID: 33793746.

6. Niu X, Rothe K, Chen M, Grasedieck S, Li R, Nam SE, Zhang X, Novakovskiy G, Ahn YH, Maksakova IA, Lai S, Zhang H, Yan J, Liu H, Zhao Y, Wu D, Ge Y, Wasserman W, Rouhi A, Kuchenbauer FC, Yip CK, Zhang Z, Jiang X. Targeting AXL Kinase Sensitizes Leukemic Stem and Progenitor Cells to Venetoclax Treatment in Acute Myeloid Leukemia. Blood. 2021 Mar 30:blood.2020007651. doi: 10.1182/blood.2020007651. Epub ahead of print. PMID: 33786587.

7. Nguyen J, Pepin D, Tropini C. Cause or effect? The spatial organization of pathogens and the gut microbiota in disease. Microbes Infect. 2021 Mar 25:104815. doi: 10.1016/j.micinf.2021.104815. Epub ahead of print. PMID: 33775859.

Mar 29, Pubcrawler Hits:

1. Shimell JJ, Globa A, Sepers MD, Wild AR, Matin N, Raymond LA, Bamji SX. Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyl transferase. J Cell Sci. 2021 Mar 23:jcs.254276. doi: 10.1242/jcs.254276. Epub ahead of print. PMID: 33758079.

2. Dixon-McDougall T, Brown CJ. Independent domains for recruitment of PRC1 and PRC2 by human XIST. PLoS Genet. 2021 Mar 22;17(3):e1009123. doi: 10.1371/journal.pgen.1009123. Epub ahead of print. PMID: 33750950.

3. Arbaeen AF, Schubert P, Sheffield WP, Devine DV. Pathogen reduction of whole blood: Supplementing fibrinogen partly corrects clot formation in a massive transfusion model. Transfusion. 2021 Mar 21. doi: 10.1111/trf.16382. Epub ahead of print. PMID: 33745131.

4. Notonier S, Werner AZ, Kuatsjah E, Dumalo L, Abraham PE, Hatmaker EA, Hoyt CB, Amore A, Ramirez KJ, Woodworth SP, Klingeman DM, Giannone RJ, Guss AM, Hettich RL, Eltis LD, Johnson CW, Beckham GT. Metabolism of syringyl lignin-derived compounds in Pseudomonas putida enables convergent production of 2-pyrone-4,6-dicarboxylic acid. Metab Eng. 2021 Mar 16;65:111-122. doi: 10.1016/j.ymben.2021.02.005. Epub ahead of print. PMID: 33741529.

5. Safabakhsh S, Panwar P, Barichello S, Sangha SS, Hanson PJ, Van Petegem F, Laksman Z. The Role of Phosphorylation in Atrial Fibrillation: A Focus on Mass Spectrometry Approaches. Cardiovasc Res. 2021 Mar 21:cvab095. doi: 10.1093/cvr/cvab095. Epub ahead of print. PMID: 33744917.

6. Danescu A, Rens EG, Rehki J, Woo J, Akazawa T, Fu K, Edelstein-Keshet L, Richman JM. Symmetry and fluctuation of cell movements in neural crest-derived facial mesenchyme. Development. 2021 Mar 23:dev.193755. doi: 10.1242/dev.193755. Epub ahead of print. PMID: 33757991.

7. Baradaran-Heravi A, Balgi AD, Hosseini-Farahabadi S, Choi K, Has C, Roberge M. Effect of small molecule eRF3 degraders on premature termination codon readthrough. Nucleic Acids Res. 2021 Mar 25:gkab194. doi: 10.1093/nar/gkab194. Epub ahead of print. PMID: 33764477.

8. Slaine PD, Kleer M, Duguay BA, Pringle ES, Kadijk E, Ying S, Balgi A, Roberge M, McCormick C, Khaperskyy DA. Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation. J Virol. 2021 Mar 24:JVI.00453-21. doi: 10.1128/JVI.00453-21. Epub ahead of print. PMID: 33762409.

9. Beskrovnaya P, Sexton DL, Golmohammadzadeh M, Hashimi A, Tocheva EI. Structural, Metabolic and Evolutionary Comparison of Bacterial Endospore and Exospore Formation. Front Microbiol. 2021 Mar 9;12:630573. doi: 10.3389/fmicb.2021.630573. PMID: 33767680; PMCID: PMC7985256.

Mar 22, Pubcrawler Hits:

1. Kuo CH, Huang YH, Chen PK, Lee GH, Tang MJ, Conway EM, Shi GY, Wu HL. VEGF-Induced Endothelial Podosomes via ROCK2-Dependent Thrombomodulin Expression Initiate Sprouting Angiogenesis. Arterioscler Thromb Vasc Biol. 2021 Mar 18:ATVBAHA121315931. doi: 10.1161/ATVBAHA.121.315931. Epub ahead of print. PMID: 33730876.

2. Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M. A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors. Transfusion. 2021 Mar 18. doi: 10.1111/trf.16364. Epub ahead of print. PMID: 33734448.

3. Sheng-Huei Lin C, Chan ACK, Vermeulen J, Brockerman J, Soni AS, Tanner ME, Gaynor EC, McIntosh LP, Simorre JP, Murphy MEP. Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni. J Biol Chem. 2021 Mar 9:100528. doi: 10.1016/j.jbc.2021.100528. Epub ahead of print. PMID: 33711341.

4. Ulloa O, Henríquez-Castillo C, Ramírez-Flandes S, Plominsky AM, Murillo AA, Morgan-Lang C, Hallam SJ, Stepanauskas R. The cyanobacterium Prochlorococcus has divergent light-harvesting antennae and may have evolved in a low-oxygen ocean. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2025638118. doi: 10.1073/pnas.2025638118. PMID: 33707213.

5. Demir F, Kizhakkedathu JN, Rinschen MM, Huesgen PF. MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets. Anal Chem. 2021 Mar 17. doi: 10.1021/acs.analchem.1c00310. Epub ahead of print. PMID: 33729755.

6. Abbasi U, Abbina S, Gill A, Bhagat V, Kizhakkedathu JN. A facile colorimetric method for the quantification of labile iron pool and total iron in cells and tissue specimens. Sci Rep. 2021 Mar 16;11(1):6008. doi: 10.1038/s41598-021-85387-z. PMID: 33727584; PMCID: PMC7971025.

7. Mulligan VK, Workman S, Sun T, Rettie S, Li X, Worrall LJ, Craven TW, King DT, Hosseinzadeh P, Watkins AM, Renfrew PD, Guffy S, Labonte JW, Moretti R, Bonneau R, Strynadka NCJ, Baker D. Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2012800118. doi: 10.1073/pnas.2012800118. PMID: 33723038.

Mar 15, Pubcrawler Hits:

1. Nam SE, Cheung YWS, Nguyen TN, Gong M, Chan S, Lazarou M, Yip CK. Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5. Commun Biol. 2021 Mar 5;4(1):291. doi: 10.1038/s42003-021-01830-x. PMID: 33674710.

Mar 8, Pubcrawler Hits:

1. Yip W, Hughes MR, Li Y, Cait A, Hirst M, Mohn WW, McNagny KM. Butyrate Shapes Immune Cell Fate and Function in Allergic Asthma. Front Immunol. 2021 Feb 15;12:628453. doi: 10.3389/fimmu.2021.628453. PMID: 33659009; PMCID: PMC7917140.

Mar 1, Pubcrawler Hits:

1. Klionsky DJ...Yip CK...(+ ~3000 others)...Tong C-K. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Feb 8:1-382. doi: 10.1080/15548627.2020.1797280. Epub ahead of print. PMID: 33634751. 

2. Schubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV. Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation. Transfusion. 2021 Feb 24. doi: 10.1111/trf.16337. Epub ahead of print. PMID: 33629371.

3. Dill-McFarland KA, König SG, Mazel F, Oliver DC, McEwen LM, Hong KY, Hallam SJ. An integrated, modular approach to data science education in microbiology. PLoS Comput Biol. 2021 Feb 25;17(2):e1008661. doi: 10.1371/journal.pcbi.1008661. PMID: 33630850.

4. Rens C, Chao JD, Sexton DL, Tocheva EI, Av-Gay Y. Roles for phthiocerol dimycocerosate lipids in Mycobacterium tuberculosis pathogenesis. Microbiology (Reading). 2021 Feb 25. doi: 10.1099/mic.0.001042. Epub ahead of print. PMID: 33629944.

Feb 22, Pubcrawler Hits:

1. Balaton BP, Fornes O, Wasserman WW, Brown CJ. Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing. Epigenetics Chromatin. 2021 Feb 17;14(1):12. doi: 10.1186/s13072-021-00386-8. PMID: 33597016.

2. Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So-Osman C, Wood E, Devine DV, Spitalnik SL; ISBT COVID-19 Working Group. ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group. Vox Sang. 2021 Feb 12. doi: 10.1111/vox.13076. Epub ahead of print. PMID: 33578447.

3. Kumaran K, Krishnaveni GV, Suryanarayana KG, Prasad MP, Belavendra A, Atkinson S, Balasubramaniam R, Bandsma RHJ, Bhutta ZA, Chandak GR, Comelli EM, Davidge ST, Dennis CL, Hammond GL, Jha P, Joseph KS, Joshi SR, Krishna M, Lee K, Lye S, McGowan P, Nepomnaschy P, Padvetnaya V, Pyne S, Sachdev HS, Sahariah SA, Singhal N, Trasler J, Yajnik CS, Baird J, Barker M, Martin MC, Husain N, Sellen D, Fall CHD, Shah PS, Matthews SG. Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally-Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): a Healthy Life Trajectories Initiative (HeLTI) Study. BMJ Open. 2021 Feb 16;11(2):e045862. doi: 10.1136/bmjopen-2020-045862. PMID: 33593789.

4. Lismer A, Dumeaux V, Lafleur C, Lambrot R, Brind'Amour J, Lorincz MC, Kimmins S. Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring. Dev Cell. 2021 Feb 15:S1534-5807(21)00072-1. doi: 10.1016/j.devcel.2021.01.014. Epub ahead of print. PMID: 33596408.

5. Tamura K, Dejean G, Van Petegem F, Brumer H. Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota. J Biol Chem. 2021 Feb 12:100415. doi: 10.1016/j.jbc.2021.100415. Epub ahead of print. PMID: 33587952.

6. Maheux AF, Boudreau DK, Abed JY, Bérubé È, Brodeur S, Bernard KA, Hashimi A, Ducrey É, Guay ÉF, Raymond F, Corbeil J, Domingo MC, Roy PH, Boissinot M, Tocheva EI, Omar RF. Criibacterium bergeronii gen. nov., sp. nov., a new member of the family Peptostreptococcaceae, isolated from human clinical samples. Int J Syst Evol Microbiol. 2021 Feb 15. doi: 10.1099/ijsem.0.004691. Epub ahead of print. PMID: 33586648.

7. Turgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021 Feb 18. doi: 10.1038/s41388-021-01680-1. Epub ahead of print. PMID: 33603169.

Feb 15, Pubcrawler Hits:

1. Heidari E, Harrison AN, Jafarinia E, Tavasoli AR, Almadani N, Molday RS, Garshasbi M. Novel variants in critical domains of ATP8A2 and expansion of clinical spectrum. Hum Mutat. 2021 Feb 10. doi: 10.1002/humu.24180. Epub ahead of print. PMID: 33565221.

2. Mischkulnig M, Kiesel B, Lötsch D, Roetzer T, Borkovec M, Wadiura LI, Roessler K, Hervey-Jumper S, Penninger JM, Berger MS, Widhalm G, Erhart F. Heme Biosynthesis mRNA Expression Signature: Towards a Novel Prognostic Biomarker in Patients with Diffusely Infiltrating Gliomas. Cancers (Basel). 2021 Feb 7;13(4):662. doi: 10.3390/cancers13040662. PMID: 33562253.

Feb 8, Pubcrawler Hits:

1. Rayani K, Seffernick J, Li AY, Davis JP, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. Binding of calcium and magnesium to human cardiac Troponin C. J Biol Chem. 2021 Feb 3:100350. doi: 10.1016/j.jbc.2021.100350. Epub ahead of print. PMID: 33548225.

2. Woll KA, Haji-Ghassemi O, Van Petegem F. Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM. Nat Commun. 2021 Feb 5;12(1):807. doi: 10.1038/s41467-021-21141-3. PMID: 33547325.

3. Holman PJ, Raineki C, Chao A, Grewal R, Haghighat S, Fung C, Morgan E, Ellis L, Yu W, Weinberg J. Altered social recognition memory and hypothalamic neuropeptide expression in adolescent male and female rats following prenatal alcohol exposure and/or early-life adversity. Psychoneuroendocrinology. 2021 Jan 21;126:105146. doi: 10.1016/j.psyneuen.2021.105146. Epub ahead of print. PMID: 33517167.

Feb 1, Pubcrawler Hits:

1. Lin H, Ascher DB, Myung Y, Lamborg CH, Hallam SJ, Gionfriddo CM, Holt KE, Moreau JW. Mercury methylation by metabolically versatile and cosmopolitan marine bacteria. ISME J. 2021 Jan 27. doi: 10.1038/s41396-020-00889-4. Epub ahead of print. PMID: 33504941.

2. Song X, Ji H, Li Y, Xiong Y, Qiu L, Zhong R, Tian M, Kizhakkedathu JN, Su B, Wei Q, Zhao W, Zhao C. Transient blood thinning during extracorporeal blood purification via the inactivation of coagulation factors by hydrogel microspheres. Nat Biomed Eng. 2021 Jan 25. doi: 10.1038/s41551-020-00673-x. Epub ahead of print. PMID: 33495638.

3. Mora M, Mell JC, Ehrlich GD, Ehrlich RL, Redfield RJ. Genome-wide analysis of DNA uptake across the outer membrane of naturally competent Haemophilus influenzae. iScience. 2020 Dec 30;24(1):102007. doi: 10.1016/j.isci.2020.102007. PMID: 33490915; PMCID: PMC7811141.

Jan 25, Pubcrawler Hits:

1. Shpilka T, Du Y, Yang Q, Melber A, Uma Naresh N, Lavelle J, Kim S, Liu P, Weidberg H, Li R, Yu J, Zhu LJ, Strittmatter L, Haynes CM. UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans. Nat Commun. 2021 Jan 20;12(1):479. doi: 10.1038/s41467-020-20784-y. PMID: 33473112.

Jan 18, Pubcrawler Hits:

1. Terada T, Kulkarni JA, Huynh A, Chen S, van der Meel R, Tam YYC, Cullis PR. Characterization of Lipid Nanoparticles Containing Ionizable Cationic Lipids Using Design-of-Experiments Approach. Langmuir. 2021 Jan 13. doi: 10.1021/acs.langmuir.0c03039. Epub ahead of print. PMID: 33439022.

2. Martin BJE, Brind'Amour J, Kuzmin A, Jensen KN, Liu ZC, Lorincz M, Howe LJ. Transcription shapes genome-wide histone acetylation patterns. Nat Commun. 2021 Jan 11;12(1):210. doi: 10.1038/s41467-020-20543-z. PMID: 33431884.

3. Mohamud Y, Xue YC, Liu H, Ng CS, Bahreyni A, Jan E, Luo H. The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy. Biochem Biophys Res Commun. 2021 Jan 8;540:75-82. doi: 10.1016/j.bbrc.2020.12.091. Epub ahead of print. PMID: 33450483.

4. Gerak CAN, Cho SY, Kolesnikov M, Okon M, Murphy MEP, Sessions RB, Roberge M, McIntosh LP. Biophysical characterization of the ETV6 PNT domain polymerization interfaces. J Biol Chem. 2021 Jan 12:100284. doi: 10.1016/j.jbc.2021.100284. Epub ahead of print. PMID: 33450226.

5. Amenyogbe N, Dimitriu P, Smolen KK, Brown EM, Shannon CP, Tebbutt SJ, Cooper PJ, Marchant A, Goetghebuer T, Esser M, Finlay BB, Kollmann TR, Mohn WW. Biogeography of the Relationship between the Child Gut Microbiome and Innate Immune System. mBio. 2021 Jan 12;12(1):e03079-20. doi: 10.1128/mBio.03079-20. PMID: 33436437.

6. Millington JW, Brownrigg GP, Chao C, Sun Z, Basner-Collins PJ, Wat LW, Hudry B, Miguel-Aliaga I, Rideout EJ. Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity. Elife. 2021 Jan 15;10:e58341. doi: 10.7554/eLife.58341. Epub ahead of print. PMID: 33448263.

Jan 11, Pubcrawler Hits:

1. Terada T, Kulkarni JA, Huynh A, Tam YYC, Cullis P. Protective Effect of Edaravone against Cationic Lipid-Mediated Oxidative Stress and Apoptosis. Biol Pharm Bull. 2021;44(1):144-149. doi: 10.1248/bpb.b20-00679. PMID: 33390543.

2. Perez-Borrajero C, Heinkel F, Gsponer J, McIntosh LP. Conformational Plasticity and DNA-Binding Specificity of the Eukaryotic Transcription Factor Pax5. Biochemistry. 2021 Jan 5. doi: 10.1021/acs.biochem.0c00737. Epub ahead of print. PMID: 33398994.

3. Mesnil M, Defamie N, Naus C, Sarrouilhe D. Brain Disorders and Chemical Pollutants: A Gap Junction Link? Biomolecules. 2020 Dec 31;11(1):E51. doi: 10.3390/biom11010051. PMID: 33396565.

4. Hepburn M, Saltzberg DJ, Lee L, Fang S, Atkinson C, Strynadka NCJ, Sali A, Lees-Miller SP, Schriemer DC. The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex. Structure. 2020 Dec 30:S0969-2126(20)30473-1. doi: 10.1016/j.str.2020.12.006. Epub ahead of print. PMID: 33412091.

5. Moulson AJ, Av-Gay Y. BCG immunomodulation: From the 'hygiene hypothesis' to COVID-19. Immunobiology. 2020 Dec 24;226(1):152052. doi: 10.1016/j.imbio.2020.152052. Epub ahead of print. PMID: 33418320.

Jan 4, Pubcrawler Hits:

1. Noonan AJC, Qiu Y, Ho JCH, Ocampo J, Vreugdenhil KA, Marr RA, Zhao Z, Yoshikuni Y, Hallam SJ. CRAGE-mediated insertion of fluorescent chromosomal markers for accurate and scalable measurement of co-culture dynamics in Escherichia coli. Synth Biol (Oxf). 2020 Sep 3;5(1):ysaa015. doi: 10.1093/synbio/ysaa015. PMID: 33381654; PMCID: PMC7751189.

2. Garces FA, Scortecci JF, Molday RS. Functional Characterization of ABCA4 Missense Variants Linked to Stargardt Macular Degeneration. Int J Mol Sci. 2020 Dec 27;22(1):E185. doi: 10.3390/ijms22010185. PMID: 33375396.

3. Tam V, Chen P, Yee A, Solis N, Klein T, Kudelko M, Sharma R, Chan WC, Overall CM, Haglund L, Sham PC, Cheah KSE, Chan D. DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics. Elife. 2020 Dec 31;9:e64940. doi: 10.7554/eLife.64940. Epub ahead of print. PMID: 33382035.

4. McLean MA, Niknafs N, Scoten OC, Chau CMY, MacKay M, Weinberg J, Synnes A, Miller SP, Grunau RE. Sensory processing and cortisol at age 4 years: Procedural pain-related stress in children born very preterm. Dev Psychobiol. 2020 Dec 29. doi: 10.1002/dev.22079. Epub ahead of print. PMID: 33377181.

5. Beskrovnaya P, Fakih D, Morneau I, Hashimi A, Bello DG, Xing S, Nanci A, Huan T, Tocheva EI. No endospore formation confirmed in members of the phylum Proteobacteria. Appl Environ Microbiol. 2020 Dec 18:AEM.02312-20. doi: 10.1128/AEM.02312-20. Epub ahead of print. PMID: 33355101.

6. Paolino M, Koglgruber R, Cronin SJF, Uribesalgo I, Rauscher E, Harreiter J, Schuster M, Bancher-Todesca D, Pranjic B, Novatchkova M, Fededa JP, White AJ, Sigl V, Dekan S, Penz T, Bock C, Kenner L, Holländer GA, Anderson G, Kautzky-Willer A, Penninger JM. RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy. Nature. 2020 Dec 23. doi: 10.1038/s41586-020-03071-0. Epub ahead of print. PMID: 33361811.


Dec 28, Pubcrawler Hits:

1. Gerak CAN, Zhang SM, Balgi AD, Sadowski IJ, Sessions RB, McIntosh LP, Roberge M. A Multipronged Screening Approach Targeting Inhibition of ETV6 PNT Domain Polymerization. SLAS Discov. 2020 Dec 21:2472555220979599. doi: 10.1177/2472555220979599. Epub ahead of print. PMID: 33345679.

2. Hillebrand GG, Dimitriu P, Malik K, Park Y, Qu D, Mohn WW, Kong R. Temporal Variation of the Facial Skin Microbiome: A 2-Year Longitudinal Study in Healthy Adults. Plast Reconstr Surg. 2021 Jan 1;147(1S-2):50S-61S. doi: 10.1097/PRS.0000000000007621. PMID: 33347075.

Dec 21, Pubcrawler Hits:

1. M A Basher AR, Hallam SJ. Leveraging heterogeneous network embedding for metabolic pathway prediction. Bioinformatics. 2020 Oct 20:btaa906. doi: 10.1093/bioinformatics/btaa906. Epub ahead of print. PMID: 33305310.

2. Márquez AC, Shanina I, Horwitz MS. Multiple Sclerosis-Like Symptoms in Mice Are Driven by Latent γHerpesvirus-68 Infected B Cells. Front Immunol. 2020 Nov 19;11:584297. doi: 10.3389/fimmu.2020.584297. PMID: 33329556; PMCID: PMC7711133.

3. Shannon CP, Blimkie TM, Ben-Othman R, Gladish N, Amenyogbe N, Drissler S, Edgar RD, Chan Q, Krajden M, Foster LJ, Kobor MS, Mohn WW, Brinkman RR, Le Cao KA, Scheuermann RH, Tebbutt SJ, Hancock REW, Koff WC, Kollmann TR, Sadarangani M, Lee AH. Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small Cohort. Front Immunol. 2020 Nov 30;11:578801. doi: 10.3389/fimmu.2020.578801. PMID: 33329547; PMCID: PMC7734088.

4. Gómez-Aleza C, Nguyen B, Yoldi G, Ciscar M, Barranco A, Hernández-Jiménez E, Maetens M, Salgado R, Zafeiroglou M, Pellegrini P, Venet D, Garaud S, Trinidad EM, Benítez S, Vuylsteke P, Polastro L, Wildiers H, Simon P, Lindeman G, Larsimont D, Van den Eynden G, Velghe C, Rothé F, Willard-Gallo K, Michiels S, Muñoz P, Walzer T, Planelles L, Penninger J, Azim HA Jr, Loi S, Piccart M, Sotiriou C, González-Suárez E. Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells. Nat Commun. 2020 Dec 10;11(1):6335. doi: 10.1038/s41467-020-20138-8. PMID: 33303745; PMCID: PMC7728758.

Dec 14, Pubcrawler Hits:

1. Farrera-Calderon RG, Pallegar P, Westbye AB, Wiesmann C, Lang AS, Beatty JT. The CckA-ChpT-CtrA phosphorelay controlling Rhodobacter capsulatus gene transfer agent (RcGTA) production is bi-directional and regulated by cyclic-di-GMP. J Bacteriol. 2020 Dec 7:JB.00525-20. doi: 10.1128/JB.00525-20. Epub ahead of print. PMID: 33288624.

2. Chazeirat T, Denamur S, Bojarski KK, Andrault PM, Sizaret D, Zhang F, Saidi A, Tardieu M, Linhardt RJ, Labarthe F, Brömme D, Samsonov SA, Lalmanach G, Lecaille F. The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V. Carbohydr Polym. 2021 Feb 1;253:117261. doi: 10.1016/j.carbpol.2020.117261. Epub 2020 Oct 20. PMID: 33278943.

3. Salmikangas S, Laiho JE, Kalander K, Laajala M, Honkimaa A, Shanina I, Oikarinen S, Horwitz MS, Hyöty H, Marjomäki V. Detection of Viral -RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues. Microorganisms. 2020 Dec 4;8(12):E1928. doi: 10.3390/microorganisms8121928. PMID: 33291747.

4. Overall CM. The Human Proteome: 90% in the Light, 10% on the Dark Side. J Proteome Res. 2020 Dec 4;19(12):4731-4734. doi: 10.1021/acs.jproteome.0c00914. PMID: 33272019.

5. Jenkins ML, Harris NJ, Dalwadi U, Fleming KD, Ziemianowicz DS, Rafiei A, Martin EM, Schriemer DC, Yip CK, Burke JE. The substrate specificity of the human TRAPPII complex's Rab-guanine nucleotide exchange factor activity. Commun Biol. 2020 Dec 4;3(1):735. doi: 10.1038/s42003-020-01459-2. PMID: 33277614; PMCID: PMC7719173.

6. Tsukasaki M, Huynh NC, Okamoto K, Muro R, Terashima A, Kurikawa Y, Komatsu N, Pluemsakunthai W, Nitta T, Abe T, Kiyonari H, Okamura T, Sakai M, Matsukawa T, Matsumoto M, Kobayashi Y, Penninger JM, Takayanagi H. Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution. Nat Metab. 2020 Dec 7. doi: 10.1038/s42255-020-00318-y. Epub ahead of print. PMID: 33288951.

Dec 7, Pubcrawler Hits:

1. Long RKM, Moriarty KP, Cardoen B, Gao G, Vogl AW, Jean F, Hamarneh G, Nabi IR. Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum. Sci Rep. 2020 Dec 1;10(1):20937. doi: 10.1038/s41598-020-77170-3. PMID: 33262363; PMCID: PMC7708840.

2. Ben-Othman R, Cai B, Liu AC, Varankovich N, He D, Blimkie TM, Lee AH, Gill EE, Novotny M, Aevermann B, Drissler S, Shannon CP, McCann S, Marty K, Bjornson G, Edgar RD, Lin DTS, Gladish N, Maclsaac J, Amenyogbe N, Chan Q, Llibre A, Collin J, Landais E, Le K, Reiss SM, Koff WC, Havenar-Daughton C, Heran M, Sangha B, Walt D, Krajden M, Crotty S, Sok D, Briney B, Burton DR, Duffy D, Foster LJ, Mohn WW, Kobor MS, Tebbutt SJ, Brinkman RR, Scheuermann RH, Hancock REW, Kollmann TR, Sadarangani M. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. Front Immunol. 2020 Nov 4;11:580373. doi: 10.3389/fimmu.2020.580373. PMID: 33250895; PMCID: PMC7672042.

3. Yang H, Mirsepasi-Lauridsen HC, Struve C, Allaire JM, Sivignon A, Vogl W, Bosman ES, Ma C, Fotovati A, Reid GS, Li X, Petersen AM, Gouin SG, Barnich N, Jacobson K, Yu HB, Krogfelt KA, Vallance BA. Ulcerative Colitis-associated E. coli pathobionts potentiate colitis in susceptible hosts. Gut Microbes. 2020 Dec 1:1-19. doi: 10.1080/19490976.2020.1847976. Epub ahead of print. PMID: 33258388.

Nov 30, Pubcrawler Hits:

1. Kulkarni JA, Thomson SB, Zaifman J, Leung J, Wagner PK, Hill A, Tam YYC, Cullis PR, Petkau TL, Leavitt BR. Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles. Nanoscale. 2020 Nov 26. doi: 10.1039/d0nr06816k. Epub ahead of print. PMID: 33241838.

2. Schulze HG, Rangan S, Vardaki M, Iworima D, Kieffer T, Blades M, Turner R, Piret JM. EXPRESS: Augmented Two-Dimensional Correlation Spectroscopy for the Joint Analysis of Correlated Changes in Spectroscopic and Disparate Sources. Appl Spectrosc. 2020 Nov 24:3702820979331. doi: 10.1177/0003702820979331. Epub ahead of print. PMID: 33231477.

3. Canals Hernaez D, Hughes MR, Dean P, Bergqvist P, Samudio I, Blixt O, Wiedemeyer K, Li Y, Bond C, Cruz E, Köbel M, Gilks B, Roskelley CD, McNagny KM. PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin. J Immunother Cancer. 2020 Nov;8(2):e001128. doi: 10.1136/jitc-2020-001128. PMID: 33243933.

4. Sullivan KE, Kendrick RM, Cembrowski MS. Elucidating memory in the brain via single-cell transcriptomics. J Neurochem. 2020 Nov 23. doi: 10.1111/jnc.15250. Epub ahead of print. PMID: 33230878.

Nov 23, Pubcrawler Hits:

1. Gazitúa MC, Vik DR, Roux S, Gregory AC, Bolduc B, Widner B, Mulholland MR, Hallam SJ, Ulloa O, Sullivan MB. Potential virus-mediated nitrogen cycling in oxygen-depleted oceanic waters. ISME J. 2020 Nov 16. doi: 10.1038/s41396-020-00825-6. Epub ahead of print. PMID: 33199808.

2. Kubiura-Ichimaru M, Ito T, Lefebvre L, Tada M. Cyclic DNA remethylation following active demethylation at euchromatic regions in mouse embryonic stem cells. Chromosome Res. 2020 Nov 17. doi: 10.1007/s10577-020-09645-y. Epub ahead of print. PMID: 33205231.

3. Khater IM, Nabi IR, Hamarneh G. A Review of Super-Resolution Single-Molecule Localization Microscopy Cluster Analysis and Quantification Methods. Patterns (N Y). 2020 Jun 12;1(3):100038. doi: 10.1016/j.patter.2020.100038. PMID: 33205106; PMCID: PMC7660399.

4. Attwood KM, Robichaud A, Westhaver LP, Castle EL, Brandman DM, Balgi AD, Roberge M, Colp P, Croul S, Kim I, McCormick C, Corcoran JA, Weeks A. Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells. Cell Death Dis. 2020 Nov 17;11(11):989. doi: 10.1038/s41419-020-03159-5. PMID: 33203845; PMCID: PMC7673037.

5. Lee J, Worrall LJ, Vuckovic M, Rosell FI, Gentile F, Ton AT, Caveney NA, Ban F, Cherkasov A, Paetzel M, Strynadka NCJ. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun. 2020 Nov 18;11(1):5877. doi: 10.1038/s41467-020-19662-4. PMID: 33208735.

6. Fennell LM, Gomez Diaz C, Deszcz L, Kavirayani A, Hoffmann D, Yanagitani K, Schleiffer A, Mechtler K, Hagelkruys A, Penninger J, Ikeda F. Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. EMBO J. 2020 Nov 20:e103303. doi: 10.15252/embj.2019103303. Epub ahead of print. PMID: 33215740.

7. Stebbing J, Sánchez Nievas G, Falcone M, Youhanna S, Richardson P, Ottaviani S, Shen JX, Sommerauer C, Tiseo G, Ghiadoni L, Virdis A, Monzani F, Rizos LR, Forfori F, Avendaño-Céspedes A, De Marco S, Carrozzi L, Lena F, Sánchez-Jurado PM, Lacerenza LG, Cesira N, Caldevilla-Bernardo D, Perrella A, Niccoli L, Méndez LS, Matarrese D, Goletti D, Tan YJ, Monteil V, Dranitsaris G, Cantini F, Farcomeni A, Dutta S, Burley SK, Zhang H, Pistello M, Li W, Mas Romero M, Andrés Pretel F, Simón-Talero RS, García-Molina R, Kutter C, Felce JH, Nizami ZF, Miklosi AG, Penninger JM, Menichetti F, Mirazimi A, Abizanda P, Lauschke VM. JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality. Sci Adv. 2020 Nov 13:eabe4724. doi: 10.1126/sciadv.abe4724. Epub ahead of print. PMID: 33187978.

8. Choi JR, Lee JH, Xu A, Matthews K, Xie S, Duffy SP, Ma H. Monolithic hydrogel nanowells-in-microwells enabling simultaneous single cell secretion and phenotype analysis. Lab Chip. 2020 Nov 17. doi: 10.1039/d0lc00965b. Epub ahead of print. PMID: 33201962.

9. Berryman S, Matthews K, Lee JH, Duffy SP, Ma H. Image-based phenotyping of disaggregated cells using deep learning. Commun Biol. 2020 Nov 13;3(1):674. doi: 10.1038/s42003-020-01399-x. PMID: 33188302; PMCID: PMC7666170.

Nov 16, Pubcrawler Hits:

1. Gammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R. Buffy coat platelets coming to America: Are we ready? Transfusion. 2020 Nov 10. doi: 10.1111/trf.16184. Epub ahead of print. PMID: 33174258.

2. Shim YA, Weliwitigoda A, Campbell T, Dosanjh M, Johnson P. Splenic erythroid progenitors decrease TNFα production by macrophages and reduce systemic inflammation in a mouse model of T cell-induced colitis. Eur J Immunol. 2020 Nov 12. doi: 10.1002/eji.202048687. Epub ahead of print. PMID: 33180325.

3. Majewski DD, Lyons BJE, Atkinson CE, Strynadka NCJ. Cryo-EM analysis of the SctV cytosolic domain from the enteropathogenic E. coli T3SS injectisome. J Struct Biol. 2020 Oct 28;212(3):107660. doi: 10.1016/j.jsb.2020.107660. Epub ahead of print. PMID: 33129970.

4. Monteil V, Dyczynski M, Lauschke VM, Kwon H, Wirnsberger G, Youhanna S, Zhang H, S Slutsky A, Hurtado Del Pozo C, Horn M, Montserrat N, Penninger JM, Mirazimi A. Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection. EMBO Mol Med. 2020 Nov 12:e13426. doi: 10.15252/emmm.202013426. Epub ahead of print. PMID: 33179852.

5. Penninger JM, Grant MB, Sung JJY. The Role of Angiotensin Converting Enzyme 2 (ACE2) in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection. Gastroenterology. 2020 Oct 29:S0016-5085(20)35327-0. doi: 10.1053/j.gastro.2020.07.067. Epub ahead of print. PMID: 33130103.

Nov 9, Pubcrawler Hits:

1. Berndt AJ, Othonos KM, Lian T, Flibotte S, Miao M, Buiyan S, Cho RY, Fong JS, Hur SA, Pavlidis P, Allan DW. A low affinity cis-regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons. Elife. 2020 Oct 30;9:e59650. doi: 10.7554/eLife.59650. Epub ahead of print. PMID: 33124981.

2. Vesnaver E, Goldman M, O'Brien S, MacPherson P, Butler-Foster T, Lapierre D, Otis J, Devine DV, Germain M, Rosser A, MacDonagh R, Randall T, Osbourne-Sorrell W, Clement-Thorne B, Al-Bakri TB, Rubini KA, Hill NE, Presseau J. Barriers and enablers to source plasma donation by gay, bisexual and other men who have sex with men under revised eligibility criteria: protocol for a multiple stakeholder feasibility study. Health Res Policy Syst. 2020 Nov 2;18(1):131. doi: 10.1186/s12961-020-00643-4. PMID: 33138828; PMCID: PMC7605323.

3. Levy-Booth DJ, Hashimi A, Roccor R, Liu LY, Renneckar S, Eltis LD, Mohn WW. Genomics and metatranscriptomics of biogeochemical cycling and degradation of lignin-derived aromatic compounds in thermal swamp sediment. ISME J. 2020 Nov 2. doi: 10.1038/s41396-020-00820-x. Epub ahead of print. PMID: 33139871.

4. Irwin NAT, Pittis AA, Mathur V, Howe LJ, Keeling PJ, Lynn DH, Bourland WA. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Curr Biol. 2020 Oct 27:S0960-9822(20)31447-0. doi: 10.1016/j.cub.2020.09.077. Epub ahead of print. PMID: 33125869.

5. Pereira S, Cline DL, Glavas MM, Covey SD, Kieffer TJ. Tissue-specific effects of leptin on glucose and lipid metabolism. Endocr Rev. 2020 Nov 5:bnaa027. doi: 10.1210/endrev/bnaa027. Epub ahead of print. PMID: 33150398.

6. Wallert M, Nie C, Anilkumar P, Abbina S, Bhatia S, Ludwig K, Kizhakkedathu JN, Haag R, Block S. Mucin-Inspired, High Molecular Weight Virus Binding Inhibitors Show Biphasic Binding Behavior to Influenza A Viruses. Small. 2020 Nov 1:e2004635. doi: 10.1002/smll.202004635. Epub ahead of print. PMID: 33135314.

7. Millington JW, Rideout EJ. Sexual Dimorphism: Ecdysone Modulates Sex Differences in the Gut. Curr Biol. 2020 Nov 2;30(21):R1327-R1330. doi: 10.1016/j.cub.2020.08.088. PMID: 33142105.

8. Pazos M, Peters K, Boes A, Safaei Y, Kenward C, Caveney NA, Laguri C, Breukink E, Strynadka NCJ, Simorre JP, Terrak M, Vollmer W. SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. mBio. 2020 Nov 3;11(6):e02796-20. doi: 10.1128/mBio.02796-20. PMID: 33144379.

9. Cheung YWS, Nam SE, Yip CK. Recent Advances in Single-Particle Electron Microscopic Analysis of Autophagy Degradation Machinery. Int J Mol Sci. 2020 Oct 28;21(21):E8051. doi: 10.3390/ijms21218051. PMID: 33126766.

10. Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM. Human recombinant soluble ACE2 in severe COVID-19. Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24. Erratum in: Lancet Respir Med. 2020 Nov;8(11):e78. PMID: 33131609; PMCID: PMC7515587.

Nov 2, Pubcrawler Hits:

1. Toews JN, Hammond GL, Viau V. Liver at the nexus of rat postnatal HPA axis maturation and sexual dimorphism. J Endocrinol. 2020 Oct 1:JOE-20-0286.R1. doi: 10.1530/JOE-20-0286. Epub ahead of print. PMID: 33112814.

2. Cloherty APM, Olmstead AD, Ribeiro CMS, Jean F. Hijacking of Lipid Droplets by Hepatitis C, Dengue and Zika Viruses-From Viral Protein Moonlighting to Extracellular Release. Int J Mol Sci. 2020 Oct 24;21(21):E7901. doi: 10.3390/ijms21217901. PMID: 33114346.

3. Li S, Huang Z, Li X, Zhao Y, Jiang X, Wen Y, Luo H, Wang L, Guan Q, Cafeeva I, Brooks DE, Nguan CYC, Kizhakkedathu JN, Du C. Evaluation of hyperbranched polyglycerol for cold perfusion and storage of donor kidneys in a pig model of kidney autotransplantation. J Biomed Mater Res B Appl Biomater. 2020 Oct 24:e34750. doi: 10.1002/jbm.b.34750. Epub ahead of print. PMID: 33098184.

4. Richard Albert J, Au Yeung WK, Toriyama K, Kobayashi H, Hirasawa R, Brind'Amour J, Bogutz A, Sasaki H, Lorincz M. Maternal DNMT3A-dependent de novo methylation of the paternal genome inhibits gene expression in the early embryo. Nat Commun. 2020 Oct 27;11(1):5417. doi: 10.1038/s41467-020-19279-7. PMID: 33110091.

5. Price RM, Budzynski MA, Kundra S, Teves SS. Advances in visualizing transcription factor-DNA interactions. Genome. 2020 Oct 28. doi: 10.1139/gen-2020-0086. Epub ahead of print. PMID: 33113335.

6. Shin T, Hiraoka Y, Yamasaki T, Marth JD, Penninger JM, Kanai-Azuma M, Tanaka K, Kofuji S, Nishina H. MKK7-deficiency in mature neurons impairs parental behavior in mice. Genes Cells. 2020 Oct 23. doi: 10.1111/gtc.12816. Epub ahead of print. PMID: 33098150.

Oct 26, Pubcrawler Hits:

1. Sharifkhodaei Z, Auld VJ. Overexpressed Gliotactin activates BMP signaling through interfering with the Tkv-Dad association. Genome. 2020 Oct 16:1-12. doi: 10.1139/gen-2020-0026. Epub ahead of print. PMID: 33064024.

2. Hoiland RL, Fergusson NA, Mitra AR, Griesdale DEG, Devine DV, Stukas S, Cooper J, Thiara S, Foster D, Chen LYC, Lee AYY, Conway EM, Wellington CL, Sekhon MS. The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19. Blood Adv. 2020 Oct 27;4(20):4981-4989. doi: 10.1182/bloodadvances.2020002623. PMID: 33057633.

3. Price HR, Lai D, Kim H, Wright TE, Coughtrie MWH, Collier AC. Detection and quantitation of non-steroidal anti-inflammatory drug use close to the time of birth using umbilical cord tissue. Toxicol Rep. 2020 Sep 8;7:1311-1318. doi: 10.1016/j.toxrep.2020.09.003. PMID: 33072523; PMCID: PMC7548959.

4. Espinet E, Gu Z, Imbusch CD, Giese NA, Buscher M, Safavi M, Weisenburger S, Klein C, Vogel V, Falcone M, Insua-Rodriguez J, Reitberger M, Thiel V, Kossi SO, Muckenhuber A, Sarai K, Lee AY, Backx E, Zarei S, Gaida MM, Rodriguez-Paredes M, Donato E, Yen HY, Eils R, Schlesner M, Pfarr N, Hackert T, Plass C, Brors B, Steiger K, Weichenhan D, Arda HE, Rooman I, Kopp JL, Strobel O, Weichert W, Sprick MR, Trumpp A. Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin. Cancer Discov. 2020 Oct 15:CD-20-1202. doi: 10.1158/2159-8290.CD-20-1202. Epub ahead of print. PMID: 33060108.

5. Amenyogbe N, Dimitriu P, Cho P, Ruck C, Fortuno ES 3rd, Cai B, Alimenti A, Côté HCF, Maan EJ, Slogrove AL, Esser M, Marchant A, Goetghebuer T, Shannon CP, Tebbutt SJ, Kollmann TR, Mohn WW, Smolen KK. Innate Immune Responses and Gut Microbiomes Distinguish HIV-Exposed from HIV-Unexposed Children in a Population-Specific Manner. J Immunol. 2020 Oct 16:ji2000040. doi: 10.4049/jimmunol.2000040. Epub ahead of print. PMID: 33067377.

6. Overall CM. The HUPO High-Stringency Inventory of Humanity's Shared Human Proteome Revealed. J Proteome Res. 2020 Oct 19. doi: 10.1021/acs.jproteome.0c00794. Epub ahead of print. PMID: 33074000.

7. Adhikari S, Nice EC, Deutsch EW, Lane L, Omenn GS, Pennington SR, Paik YK, Overall CM, Corrales FJ, Cristea IM, Van Eyk JE, Uhlén M, Lindskog C, Chan DW, Bairoch A, Waddington JC, Justice JL, LaBaer J, Rodriguez H, He F, Kostrzewa M, Ping P, Gundry RL, Stewart P, Srivastava S, Srivastava S, Nogueira FCS, Domont GB, Vandenbrouck Y, Lam MPY, Wennersten S, Vizcaino JA, Wilkins M, Schwenk JM, Lundberg E, Bandeira N, Marko-Varga G, Weintraub ST, Pineau C, Kusebauch U, Moritz RL, Ahn SB, Palmblad M, Snyder MP, Aebersold R, Baker MS. A high-stringency blueprint of the human proteome. Nat Commun. 2020 Oct 16;11(1):5301. doi: 10.1038/s41467-020-19045-9. PMID: 33067450; PMCID: PMC7568584.

8. Genovese I, Giamogante F, Barazzuol L, Battista T, Fiorillo A, Vicario M, D'Alessandro G, Cipriani R, Limatola C, Rossi D, Sorrentino V, Poser E, Mosca L, Squitieri F, Perluigi M, Arena A, van Petegem F, Tito C, Fazi F, Giorgi C, Calì T, Ilari A, Colotti G. Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases. Cell Death Dis. 2020 Oct 15;11(10):861. doi: 10.1038/s41419-020-03063-y. PMID: 33060591; PMCID: PMC7566454.

9. Teves SS. Function through absence: Active RNA exclusion from chromosomes leads to proper cell division. J Cell Biol. 2020 Nov 2;219(11):e202009193. doi: 10.1083/jcb.202009193. PMID: 33053169.

10. Sexton DL, Tocheva EI. Ultrastructure of Exospore Formation in Streptomyces Revealed by Cryo-Electron Tomography. Front Microbiol. 2020 Sep 24;11:581135. doi: 10.3389/fmicb.2020.581135. PMID: 33072052; PMCID: PMC7541840.

Oct 19, Pubcrawler Hits:

1. Sage AP, Ng KW, Marshall EA, Stewart GL, Minatel BC, Enfield KSS, Martin SD, Brown CJ, Abraham N, Lam WL. Assessment of long non-coding RNA expression reveals novel mediators of the lung tumour immune response. Sci Rep. 2020 Oct 9;10(1):16945. doi: 10.1038/s41598-020-73787-6. PMID: 33037279.

2. Hadjesfandiari N, Levin E, Serrano K, Yi QL, Devine DV. Risk analysis of transfusion of cryoprecipitate without consideration of ABO group. Transfusion. 2020 Oct 10. doi: 10.1111/trf.16125. Epub ahead of print. PMID: 33037661.

3. Shapira T, Rankine-Wilson L, Chao JD, Pichler V, Rens C, Pfeifer T, Av-Gay Y. High-Content Screening of Eukaryotic Kinase Inhibitors Identify CHK2 Inhibitor Activity Against Mycobacterium tuberculosis. Front Microbiol. 2020 Sep 18;11:553962. doi: 10.3389/fmicb.2020.553962. PMID: 33042061; PMCID: PMC7530171.

Oct 12, Pubcrawler Hits:

1. Behroozian S, Svensson SL, Li LY, Davies JE. Broad-Spectrum Antimicrobial and Antibiofilm Activity of a Natural Clay Mineral from British Columbia, Canada. mBio. 2020 Oct 6;11(5):e02350-20. doi: 10.1128/mBio.02350-20. PMID: 33024043.

Oct 5, Pubcrawler Hits:

1. Ayala-Muñoz D, Simister R, Crowe S, Macalady J, Burgos WD. Functional redundancy imparts process stability to acidic Fe(II)-oxidizing microbial reactors. Environ Microbiol. 2020 Sep 29. doi: 10.1111/1462-2920.15259. Epub ahead of print. PMID: 32996242.

2. Fetherolf MM, Levy-Booth DJ, Navas LE, Liu J, Grigg JC, Wilson A, Katahira R, Beckham GT, Mohn WW, Eltis LD. Characterization of alkylguaiacol-degrading cytochromes P450 for the biocatalytic valorization of lignin. Proc Natl Acad Sci U S A. 2020 Sep 28:201916349. doi: 10.1073/pnas.1916349117. Epub ahead of print. PMID: 32989155.

3. M A Basher AR, McLaughlin RJ, Hallam SJ. Metabolic pathway inference using multi-label classification with rich pathway features. PLoS Comput Biol. 2020 Oct 1;16(10):e1008174. doi: 10.1371/journal.pcbi.1008174. PMID: 33001968.

4. Brink KS, Wu P, Chuong CM, Richman JM. The Effects of Premature Tooth Extraction and Damage on Replacement Timing in the Green Iguana. Integr Comp Biol. 2020 Jul 6:icaa099. doi: 10.1093/icb/icaa099. Epub ahead of print. PMID: 32974642.

5. Xiong R, Sugioka K. Improved 3D cellular morphometry of Caenorhabditis elegans embryos using a refractive index matching medium. PLoS One. 2020 Sep 30;15(9):e0238955. doi: 10.1371/journal.pone.0238955. PMID: 32997668.

6. Hasan Ali O, Bomze D, Risch L, Brugger SD, Paprotny M, Weber M, Thiel S, Kern L, Albrich WC, Kohler P, Kahlert CR, Vernazza P, Bühler PK, Schüpbach RA, Gómez-Mejia A, Popa AM, Bergthaler A, Penninger JM, Flatz L. Severe COVID-19 is associated with elevated serum IgA and antiphospholipid IgA-antibodies. Clin Infect Dis. 2020 Sep 30:ciaa1496. doi: 10.1093/cid/ciaa1496. Epub ahead of print. PMID: 32997739.

Sep 28, Pubcrawler Hits:

1. Ooshio T, Yamamoto M, Fujii K, Xin B, Watanabe K, Goto M, Okada Y, Suzuki A, Penninger JM, Nishina H, Nishikawa Y. Hepatocyte MKK7 Contributes to Restoration of the Liver Parenchyma Following Injury. Hepatology. 2020 Sep 23. doi: 10.1002/hep.31565. Epub ahead of print. PMID: 32969030.

Sep 21, Pubcrawler Hits:

1. Shirane K, Miura F, Ito T, Lorincz MC. NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing. Nat Genet. 2020 Sep 14. doi: 10.1038/s41588-020-0689-z. Epub ahead of print. PMID: 32929285.

2. Terrado M, Okon M, McIntosh LP, Plettner E. Ligand- and pH-Induced Structural Transition of Gypsy Moth Lymantria dispar Pheromone-Binding Protein 1 (LdisPBP1). Biochemistry. 2020 Sep 11. doi: 10.1021/acs.biochem.0c00592. Epub ahead of print. PMID: 32877603.

3. Hagelkruys A, Wirnsberger G, Stadlmann J, Wöhner M, Horrer M, Vilagos B, Jonsson G, Kogler M, Tortola L, Novatchkova M, Bönelt P, Hoffmann D, Koglgruber R, Steffen U, Schett G, Busslinger M, Bergthaler A, Klein C, Penninger JM. A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans. J Exp Med. 2021 Jan 4;218(1):e20200559. doi: 10.1084/jem.20200559. PMID: 32930709.

Sep 14, Pubcrawler Hits:

1. Kolic J, Beet L, Overby P, Cen HH, Panzhinskiy E, Ure DR, Cross JL, Huizinga RB, Johnson JD. Differential effects of voclosporin and tacrolimus on insulin secretion from human islets. Endocrinology. 2020 Sep 7:bqaa162. doi: 10.1210/endocr/bqaa162. Epub ahead of print. PMID: 32894758.

2. Adams A, Vogl W. ORP9 Knockdown Delays the Maturation of Junction Related Endocytic Structures in the Testis and Leads to Impaired Sperm Release†. Biol Reprod. 2020 Sep 9:ioaa159. doi: 10.1093/biolre/ioaa159. Epub ahead of print. PMID: 32901807.

3. Adams A, Vogl W, Dawson C, Raverty S, Haulena M, Skoretz SA. Laryngeal and soft palate valving in the harbour seal (Phoca vitulina). J Exp Biol. 2020 Sep 6:jeb.230201. doi: 10.1242/jeb.230201. Epub ahead of print. PMID: 32895326.

Sep 7, Pubcrawler Hits:

1. Francia V, Schiffelers RM, Cullis PR, Witzigmann D. The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy. Bioconjug Chem. 2020 Aug 31. doi: 10.1021/acs.bioconjchem.0c00366. Epub ahead of print. PMID: 32786370.

2. Jara MA, Werneck-De-Castro JP, Lubaczeuski C, Johnson JD, Bernal-Mizrachi E. Pancreatic and duodenal homeobox-1 (PDX1) contributes to β-cell mass expansion and proliferation induced by Akt/PKB pathway. Islets. 2020 Mar 3;12(2):32-40. doi: 10.1080/19382014.2020.1762471. PMID: 32876522.

3. Majewski DD, Okon M, Heinkel F, Robb CS, Vuckovic M, McIntosh LP, Strynadka NCJ. Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure. 2020 Aug 27:S0969-2126(20)30288-4. doi: 10.1016/j.str.2020.08.006. Epub ahead of print. PMID: 32877645.

4. Ibarra Moreno CA, Kraeva N, Zvaritch E, Figueroa L, Rios E, Biesecker L, Van Petegem F, Hopkins PM, Riazi S. A multi-dimensional analysis of genotype-phenotype discordance in malignant hyperthermia susceptibility. Br J Anaesth. 2020 Aug 26:S0007-0912(20)30633-4. doi: 10.1016/j.bja.2020.07.042. Epub ahead of print. PMID: 32861507.

5. O'Leary TP, Sullivan KE, Wang L, Clements J, Lemire AL, Cembrowski MS. Extensive and spatially variable within-cell-type heterogeneity across the basolateral amygdala. Elife. 2020 Sep 1;9:e59003. doi: 10.7554/eLife.59003. Epub ahead of print. PMID: 32869744.

Aug 31, Pubcrawler Hits:

1. Curtis SB, Molday LL, Garces FA, Molday RS. Functional Analysis and Classification of Homozygous and Hypomorphic ABCA4 Variants Associated with Stargardt Macular Degeneration. Hum Mutat. 2020 Aug 26. doi: 10.1002/humu.24100. Epub ahead of print. PMID: 32845050.

2. Thompson DA, Iannaccone A, Ali RR, Arshavsky VY, Audo I, Bainbridge JWB, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Dalkara D, Duncan JL, Fahim AT, Flannery JG, Gattegna R, Heckenlively JR, Heon E, Jayasundera KT, Khan NW, Klassen H, Leroy BP, Molday RS, Musch DC, Pennesi ME, Petersen-Jones SM, Pierce EA, Rao RC, Reh TA, Sahel JA, Sharon D, Sieving PA, Strettoi E, Yang P, Zacks DN; Monaciano Consortium. Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium. Transl Vis Sci Technol. 2020 Jun 3;9(7):2. doi: 10.1167/tvst.9.7.2. PMID: 32832209; PMCID: PMC7414644.

3. Noël G, Tham DKL, Guadagno E, MacVicar B, Moukhles H. The Laminin-Induced Phosphorylation of PKCδ Regulates AQP4 Distribution and Water Permeability in Rat Astrocytes. Cell Mol Neurobiol. 2020 Aug 26. doi: 10.1007/s10571-020-00944-w. Epub ahead of print. PMID: 32851539.

4. Morell M, Vogl AW, IJsseldijk LL, Piscitelli-Doshkov M, Tong L, Ostertag S, Ferreira M, Fraija-Fernandez N, Colegrove KM, Puel JL, Raverty SA, Shadwick RE. Echolocating Whales and Bats Express the Motor Protein Prestin in the Inner Ear: A Potential Marker for Hearing Loss. Front Vet Sci. 2020 Jul 17;7:429. doi: 10.3389/fvets.2020.00429. PMID: 32851016; PMCID: PMC7396497.

5. Ming J, Cronin SJF, Penninger JM. Targeting the RANKL/RANK/OPG Axis for Cancer Therapy. Front Oncol. 2020 Aug 7;10:1283. doi: 10.3389/fonc.2020.01283. PMID: 32850393; PMCID: PMC7426519.

6. Nitta T, Tsutsumi M, Nitta S, Muro R, Suzuki EC, Nakano K, Tomofuji Y, Sawa S, Okamura T, Penninger JM, Takayanagi H. Fibroblasts as a source of self-antigens for central immune tolerance. Nat Immunol. 2020 Aug 24. doi: 10.1038/s41590-020-0756-8. Epub ahead of print. PMID: 32839611.

Aug 24, Pubcrawler Hits:

1. Chamberlain TC, Cheung ST, Yoon JSJ, Ming-Lum A, Gardill BR, Shakibakho S, Dzananovic E, Ban F, Samiea A, Jawanda K, Priatel J, Krystal G, Ong CJ, Cherkasov A, Andersen RJ, McKenna SA, Van Petegem F, Mui AL. Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-inflammatory Effects through SHIP1/STAT3 Complexes. iScience. 2020 Aug 21;23(8):101433. doi: 10.1016/j.isci.2020.101433. Epub 2020 Aug 2. PMID: 32823063.

2. Ma R, Haji-Ghassemi O, Ma D, Jiang H, Lin L, Yao L, Samurkas A, Li Y, Wang Y, Cao P, Wu S, Zhang Y, Murayama T, Moussian B, Van Petegem F, Yuchi Z. Structural basis for diamide modulation of ryanodine receptor. Nat Chem Biol. 2020 Aug 17. doi: 10.1038/s41589-020-0627-5. Epub ahead of print. PMID: 32807966.

Aug 17, Pubcrawler Hits:

1. Conway EM, Pryzdial ELG. Is the COVID-19 thrombotic catastrophe complement-connected? J Thromb Haemost. 2020 Aug 6. doi: 10.1111/jth.15050. Epub ahead of print. PMID: 32762081.

2. Liu MM, Coleman S, Wilkinson L, Smith ML, Hoang T, Niyah N, Mukherjee M, Huynh S, Parker CT, Kovac J, Hancock REW, Gaynor EC. Unique inducible filamentous motility identified in pathogenic Bacillus cereus group species. ISME J. 2020 Aug 7. doi: 10.1038/s41396-020-0728-x. Epub ahead of print. PMID: 32770116.

3. Hedil M, Nakasu EYT, Nagata T, Wen J, Jan E, Michereff-Filho M, Inoue-Nagata AK. New features on the genomic organization of a novel dicistrovirus identified from the sweet potato whitefly Bemisia tabaci. Virus Res. 2020 Aug 7:198112. doi: 10.1016/j.virusres.2020.198112. Epub ahead of print. PMID: 32777388.

4. Chan ACK, Lin H, Koch D, Grass G, Nies DH, Murphy MEP. A copper site is required for iron transport by the periplasmic proteins P19 and FetP. Metallomics. 2020 Aug 11. doi: 10.1039/d0mt00130a. Epub ahead of print. PMID: 32780051.

5. Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, Matsushita M, Ara T, Yasuda H, Penninger JM, Takahashi N, Udagawa N, Kobayashi Y. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020 Aug 13;10(1):13751. doi: 10.1038/s41598-020-70817-1. PMID: 32792620.

Aug 10, Pubcrawler Hits:

1. Conley AJ, Place N, Legacki E, Hammond GL, Cunha GR, Drea CM, Weldele ML, Glickman SE. Spotted hyaenas and the sexual spectrum: reproductive endocrinology and development. J Endocrinol. 2020 Aug 1:JOE-20-0252.R1. doi: 10.1530/JOE-20-0252. Epub ahead of print. PMID: 32755997.

2. Satti S, Deng P, Matthews K, Duffy SP, Ma H. Multiplexed end-point microfluidic chemotaxis assay using centrifugal alignment. Lab Chip. 2020 Aug 4. doi: 10.1039/d0lc00311e. Epub ahead of print. PMID: 32748936.

Aug 3, Pubcrawler Hits:

1. Perez SEI, Hahn AS, Krzywinski M, Hallam SJ. Hive Panel Explorer: an interactive network visualization tool. Bioinformatics. 2020 Jul 27:btaa683. doi: 10.1093/bioinformatics/btaa683. Epub ahead of print. PMID: 32717050.

2. Botezelli JD, Overby P, Lindo L, Wang S, Haïda O, Lim GE, Templeman NM, Pauli JR, Johnson JD. Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice. Am J Physiol Endocrinol Metab. 2020 Jul 27. doi: 10.1152/ajpendo.00128.2020. Epub ahead of print. PMID: 32715748.

3. Rebollo R, Galvão-Ferrarini M, Gagnier L, Zhang Y, Ferraj A, Beck CR, Lorincz MC, Mager DL. Inter-Strain Epigenomic Profiling Reveals a Candidate IAP Master Copy in C3H Mice. Viruses. 2020 Jul 21;12(7):E783. doi: 10.3390/v12070783. PMID: 32708087.

4. Millar D, Hayes C, Jones J, Klapper E, Kniep JN, Luu HS, Noland DK, Petitti L, Poisson JL, Spaepen E, Ye Z, Maurer-Spurej E. Comparison of the platelet activation status of single-donor platelets obtained with two different cell separator technologies. Transfusion. 2020 Jul 29. doi: 10.1111/trf.15934. Epub ahead of print. PMID: 32729161.

5. Khosla K, Naus CC, Sin WC. Cx43 in Neural Progenitors Promotes Glioma Invasion in a 3D Culture System. Int J Mol Sci. 2020 Jul 23;21(15):E5216. doi: 10.3390/ijms21155216. PMID: 32717889.

July 27, Pubcrawler Hits:

1. Strilchuk AW, Meixner SC, Leung J, Safikhan N, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens Iii AP, Palumbo J, Conway EM, Pryzdial EL, Cullis P, Kastrup CJ. Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency. Blood. 2020 Jul 17:blood.2020004976. doi: 10.1182/blood.2020004976. Epub ahead of print. PMID: 32678423.

2. Haw J, Polzer J, Devine DV. Emotional labour and cord blood collection: frontline perspectives. J Health Organ Manag. 2020 Jun 9;34(5):587-601. doi: 10.1108/JHOM-10-2019-0305. PMID: 32681634.

3. Stanley M, McDowell SAT, Gordon MD. A fly rhodopsin sheds light on thermal taste. Cell Calcium. 2020 Nov;91:102259. doi: 10.1016/j.ceca.2020.102259. Epub 2020 Jul 27. PMID: 32739609.

4. Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M. Antiviral anticoagulation. Res Pract Thromb Haemost. 2020 Jul 6;4(5):774-788. doi: 10.1002/rth2.12406. PMID: 32685886; PMCID: PMC7354393.

5. Appelberg S, Gupta S, Akusjärvi SS, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, Krishnan S, Singh K, Penninger JM, Mirazimi A, Neogi U. Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells. Emerg Microbes Infect. 2020 Jul 21:1-36. doi: 10.1080/22221751.2020.1799723. Epub ahead of print. PMID: 32691695.

6. Thompson E, Eldstrom J, Fedida D. Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels. Annu Rev Pharmacol Toxicol. 2020 Jul 15. doi: 10.1146/annurev-pharmtox-010919-023645. Epub ahead of print. PMID: 32667860.

July 13, Pubcrawler Hits:

1. Witzigmann D, Kulkarni JA, Leung J, Chen S, Cullis PR, van der Meel R. Lipid nanoparticle technology for therapeutic gene regulation in the liver. Adv Drug Deliv Rev. 2020 Jul 1:S0169-409X(20)30072-7. doi: 10.1016/j.addr.2020.06.026. Epub ahead of print. PMID: 32622021; PMCID: PMC7329694.

2. Morgan-Lang C, McLaughlin R, Armstrong Z, Zhang G, Chan K, Hallam SJ. TreeSAPP: The Tree-based Sensitive and Accurate Phylogenetic Profiler. Bioinformatics. 2020 Jul 8:btaa588. doi: 10.1093/bioinformatics/btaa588. Epub ahead of print. PMID: 32637989.

3. Lee J, Kim K, Cho JH, Bae JY, O'Leary TP, Johnson JD, Bae YC, Kim EK. Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production. JCI Insight. 2020 Jul 9:135412. doi: 10.1172/jci.insight.135412. Epub ahead of print. PMID: 32644973.

4. Drayton M, Kizhakkedathu JN, Straus SK. Towards Robust Delivery of Antimicrobial Peptides to Combat Bacterial Resistance. Molecules. 2020 Jul 3;25(13):E3048. doi: 10.3390/molecules25133048. PMID: 32635310.

5. Khadilkar RJ, Ho KYL, Venkatesh B, Tanentzapf G. Integrins Modulate Extracellular Matrix Organization to Control Cell Signaling during Hematopoiesis. Curr Biol. 2020 Jul 4:S0960-9822(20)30843-5. doi: 10.1016/j.cub.2020.06.027. Epub ahead of print. PMID: 32649911.

6. Chabloz A, Schaefer JV, Kozieradzki I, Cronin SJF, Strebinger D, Macaluso F, Wald J, Rabbitts TH, Plückthun A, Marlovits TC, Penninger JM. Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol. Commun Biol. 2020 Jul 3;3(1):342. doi: 10.1038/s42003-020-1072-4. PMID: 32620833; PMCID: PMC7335062.

July 6, Pubcrawler Hits:

1. MacGillivray RTA, Conway EM. Obituary for Earl Warren Davie 1927-2020. J Thromb Haemost. 2020 Jun 30. doi: 10.1111/jth.14978. Epub ahead of print. PMID: 32608042.

2. Szeinbaum N, Nunn BL, Cavazos AR, Crowe SA, Stewart FJ, DiChristina TJ, Reinhard CT, Glass JB. Novel insights into the taxonomic diversity and molecular mechanisms of bacterial Mn(III) reduction. Environ Microbiol Rep. 2020 Jul 2. doi: 10.1111/1758-2229.12867. Epub ahead of print. PMID: 32613749.

3. Ramzy A, Tudurí E, Glavas MM, Baker RK, Mojibian M, Fox JK, O'Dwyer SM, Dai D, Hu X, Denroche HC, Edeer N, Gray SL, Verchere CB, Johnson JD, Kieffer TJ. AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects. Sci Rep. 2020 Jun 29;10(1):10518. doi: 10.1038/s41598-020-67136-w. PMID: 32601405; PMCID: PMC7324556.

4. Achazi K, Haag R, Ballauff M, Dernedde J, Kizhakkedathu JN, Maysinger D, Multhaup G. Understanding the interaction of polyelectrolyte architectures with proteins and biosystems. Angew Chem Int Ed Engl. 2020 Jun 26. doi: 10.1002/anie.202006457. Epub ahead of print. PMID: 32589355.

5. Duncan MC, Onguéné PA, Kihara I, Nebangwa DN, Naidu ME, Williams DE, Balgi AD, Andrae-Marobela K, Roberge M, Andersen RJ, Niikura M, Ntie-Kang F, Tietjen I. Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus. Molecules. 2020 Jun 24;25(12):E2903. doi: 10.3390/molecules25122903. PMID: 32599753.

June 29, Pubcrawler Hits:

1. Accili E. An ion channel in the company of a transporter. J Gen Physiol. 2020 Jul 6;152(7):e202012590. doi: 10.1085/jgp.202012590. PMID: 32579683.

2. Wang Y, Eldstrom J, Fedida D. Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes. Front Physiol. 2020 Jun 4;11:504. doi: 10.3389/fphys.2020.00504. PMID: 32581825; PMCID: PMC7287213.

3. Haage A, Wagner K, Deng W, Venkatesh B, Mitchell C, Goodwin K, Bogutz A, Lefebvre L, Van Raamsdonk CD, Tanentzapf G. Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development. Development. 2020 Jun 24:dev.184234. doi: 10.1242/dev.184234. Epub ahead of print. PMID: 32580934.

4. Nabi IR. Biography-Ivan Robert Nabi. Cancer Metastasis Rev. 2020 Jun;39(2):333. doi: 10.1007/s10555-020-09893-8. PMID: 32577925.

5. Falkowski K, Bielecka E, Thøgersen IB, Bocheńska O, Płaza K, Kalińska M, Sąsiadek L, Magoch M, Pęcak A, Wiśniewska M, Gruba N, Wysocka M, Wojtysiak A, Brzezińska-Bodal M, Sychowska K, Pejkovska A, Rehders M, Butler G, Overall CM, Brix K, Dubin G, Lesner A, Kozik A, Enghild JJ, Potempa J, Kantyka T. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. Int J Mol Sci. 2020 Jun 19;21(12):E4383. doi: 10.3390/ijms21124383. PMID: 32575583.

June 22, Pubcrawler Hits:

1. Bárdy P, Füzik T, Hrebík D, Pantůček R, Thomas Beatty J, Plevka P. Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun. 2020 Jun 15;11(1):3034. doi: 10.1038/s41467-020-16669-9. PMID: 32541663; PMCID: PMC7296036.

2. Al-Riyami AZ, Schäfer R, van der Berg K, Bloch EM, Escourt LJ, Goel R, Hindawi S, Josephson CD, Land K, McQuilten ZK, Spitalnik SL, Wood EM, Devine DV, So-Osman C; ISBT Convalescent Plasma Working Group. Clinical use of Convalescent Plasma in the COVID-19 pandemic; a transfusion-focussed gap analysis with recommendations for future research priorities. Vox Sang. 2020 Jun 15. doi: 10.1111/vox.12973. Epub ahead of print. PMID: 32542847.

3. Bloch EM, Goel R, Wendel S, Burnouf T, Al-Riyami AZ, Ang AL, DeAngelis V, Dumont LJ, Land K, Lee CK, Oreh A, Patidar G, Spitalnik SL, Vermeulen M, Hindawi S, Van den Berg K, Tiberghien P, Vrielink H, Young P, Devine D, So-Osman C; ISBT Convalescent Plasma Working Group. Guidance for the Procurement of COVID-19 Convalescent Plasma: Differences between High and Low-Middle Income Countries. Vox Sang. 2020 Jun 13. doi: 10.1111/vox.12970. Epub ahead of print. PMID: 32533868.

4. Kerr CH, Skinnider MA, Andrews DDT, Madero AM, Chan QWT, Stacey RG, Stoynov N, Jan E, Foster LJ. Dynamic rewiring of the human interactome by interferon signaling. Genome Biol. 2020 Jun 15;21(1):140. doi: 10.1186/s13059-020-02050-y. PMID: 32539747; PMCID: PMC7294662.

5. Abbina S, Takeuchi LE, Anilkumar P, Yu K, Rogalski JC, Shenoi RA, Constantinescu I, Kizhakkedathu JN. Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface. Nat Commun. 2020 Jun 16;11(1):3048. doi: 10.1038/s41467-020-16772-x. PMID: 32546688.

6. Hendi A, Mizumoto K. GFPnovo2, a brighter GFP variant for in vivo labeling in C. elegans. MicroPubl Biol. 2018 Sep 6;2018:10.17912/49YB-7K39. doi: 10.17912/49YB-7K39. PMID: 32550394; PMCID: PMC7282520.

7. Tsai K, Huang YH, Ma C, Baldwin TA, Harder KW, Vallance BA, Priatel JJ. Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen. J Immunol. 2020 Jun 15:ji1900687. doi: 10.4049/jimmunol.1900687. Epub ahead of print. PMID: 32540993.

June 15, Pubcrawler Hits:

1. Devine DV. SARS in Canada: Lessons learned for the blood operator. Transfus Med. 2020 Jun;30(3):172-173. doi: 10.1111/tme.12699. PMID: 32529741; PMCID: PMC7276835.

2. Horianopoulos LC, Hu G, Caza M, Schmitt K, Overby P, Johnson JD, Valerius O, Braus GH, Kronstad JW. The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans. mBio. 2020 Jun 9;11(3):e01127-20. doi: 10.1128/mBio.01127-20. PMID: 32518190.

3. Refaeli I, Hughes MR, Wong AK, Bissonnette MLZ, Roskelley CD, Vogl WA, Barbour SJ, Freedman BS, McNagny KM. Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease. Sci Rep. 2020 Jun 10;10(1):9419. doi: 10.1038/s41598-020-64907-3. PMID: 32523052.

4. Alexander JAN, Radaeva M, King DT, Chambers HF, Cherkasov A, Chatterjee SS, Strynadka NCJ. -Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus. J Biol Chem. 2020 Jun 9:jbc.RA120.013029. doi: 10.1074/jbc.RA120.013029. Epub ahead of print. PMID: 32518158.

June 8, Pubcrawler Hits:

1. Marshall NC, Thejoe M, Klein T, Serapio-Palacios A, Santos AS, von Krosigk N, Kizhakkedathu JN, Stoynov N, Foster LJ, Overall CM, Finlay BB. Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death. mSystems. 2020 Jun 2;5(3):e00283-20. doi: 10.1128/mSystems.00283-20. PMID: 32487743.

2. Young BP, Post KL, Chao JT, Meili F, Haas K, Loewen CJR. Sentinel Interaction Mapping (SIM) - A generic approach for the functional analysis of human disease gene variants using yeast. Dis Model Mech. 2020 May 29:dmm.044560. doi: 10.1242/dmm.044560. Epub ahead of print. PMID: 32471850.

3. Rufenach B, Christy D, Flucher BE, Bui JM, Gsponer J, Campiglio M, Van Petegem F. Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure. 2020 May 27:S0969-2126(20)30174-X. doi: 10.1016/j.str.2020.05.005. Epub ahead of print. PMID: 32492370.

June 1, Pubcrawler Hits:

1. Davies JE. In memory of Professor Arnold L. Demain. J Antibiot (Tokyo). 2020 May 28. doi: 10.1038/s41429-020-0325-2. Epub ahead of print. PMID: 32461629.

2. Shim YA, Campbell T, Weliwitigoda A, Dosanjh M, Johnson P. Regulation of CD71+TER119+ erythroid progenitor cells by CD45. Exp Hematol. 2020 May 22:S0301-472X(20)30182-X. doi: 10.1016/j.exphem.2020.05.005. Epub ahead of print. PMID: 32450207.

3. Ahmadabadi HY, Yu K, Kizhakkedathu JN. Surface modification approaches for prevention of implant associated infections. Colloids Surf B Biointerfaces. 2020 May 12;193:111116. doi: 10.1016/j.colsurfb.2020.111116. Epub ahead of print. PMID: 32447202.

4. Jain F, Longakit A, Huang JL, Van Raamsdonk CD. Endothelin signaling promotes melanoma tumorigenesis driven by constitutively active GNAQ. Pigment Cell Melanoma Res. 2020 May 26. doi: 10.1111/pcmr.12900. Epub ahead of print. PMID: 32453908.

5. Vogel Ciernia A, Link VM, Careaga M, LaSalle J, Ashwood P. Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages. Brain Behav Immun. 2020 May 23:S0889-1591(20)30260-9. doi: 10.1016/j.bbi.2020.05.058. Epub ahead of print. PMID: 32454135.

May 25, Pubcrawler Hits:

1. Phipps SM, Garry CE, Kamal S, Johnson JD, Gilmer J, Long A, Kelleher D, Duggan SP. High Content Imaging of Barrett's-Associated High Grade Dysplasia Cells Following siRNA Library Screening Reveals Acid Responsive Regulators of Cellular Transitions. Cell Mol Gastroenterol Hepatol. 2020 May 13:S2352-345X(20)30072-2. doi: 10.1016/j.jcmgh.2020.05.002. Epub ahead of print. PMID: 32416156.

2. Adak T, Morales DL, Cook AJ, Grigg JC, Murphy MEP, Tanner ME. ArnD is a deformylase involved in polymyxin resistance. Chem Commun (Camb). 2020 May 20. doi: 10.1039/d0cc02241a. Epub ahead of print. PMID: 32432293.

3. Nabi IR. Preface. Cancer Metastasis Rev. 2020 May 16. doi: 10.1007/s10555-020-09894-7. Epub ahead of print. PMID: 32417991.

4. Hughes MR, Hernaez DC, Cait J, Refaeli I, Lo B, Roskelley C, McNagny KM. A Sticky Wicket: Defining Molecular Functions for CD34 in Hematopoietic Cells. Exp Hematol. 2020 May 15:S0301-472X(20)30181-8. doi: 10.1016/j.exphem.2020.05.004. Epub ahead of print. PMID: 32422232.

5. Orthofer M, Valsesia A, Mägi R, Wang QP, Kaczanowska J, Kozieradzki I, Leopoldi A, Cikes D, Zopf LM, Tretiakov EO, Demetz E, Hilbe R, Boehm A, Ticevic M, Nõukas M, Jais A, Spirk K, Clark T, Amann S, Lepamets M, Neumayr C, Arnold C, Dou Z, Kuhn V, Novatchkova M, Cronin SJF, Tietge UJF, Müller S, Pospisilik JA, Nagy V, Hui CC, Lazovic J, Esterbauer H, Hagelkruys A, Tancevski I, Kiefer FW, Harkany T, Haubensak W, Neely GG, Metspalu A, Hager J, Gheldof N, Penninger JM. Identification of ALK in Thinness. Cell. 2020 May 13:S0092-8674(20)30497-9. doi: 10.1016/j.cell.2020.04.034. Epub ahead of print. PMID: 32442405.

May 18, Pubcrawler Hits:

1. Adams A, Vogl W. Knockdown of IP3R1 Disrupts TBC-ER Contact Sites and the Morphology of Apical Processes Encapsulating Late Spermatids. Biol Reprod. 2020 May 14. pii: ioaa074. doi: 10.1093/biolre/ioaa074. [Epub ahead of print] PubMed PMID: 32406903.

May 11, Pubcrawler Hits:

1. Anilkumar P, Lawson TB, Abbina S, Mäkelä JTA, Sabatelle RC, Takeuchi LE, Snyder BD, Grinstaff MW, Kizhakkedathu JN. Mega macromolecules as single molecule lubricants for hard and soft surfaces. Nat Commun. 2020 May 1;11(1):2139. doi: 10.1038/s41467-020-15975-6. PubMed PMID: 32358489; PubMed Central PMCID: PMC7195476.

2. Chao JT, Hollman R, Meyers WM, Meili F, Matreyek KA, Dean P, Fowler DM, Haas K, Roskelley CD, Loewen CJR. A premalignant cell-based model for functionalization and classification of PTEN variants. Cancer Res. 2020 May 4. pii: canres.3278.2019. doi: 10.1158/0008-5472.CAN-19-3278. [Epub ahead of print] PubMed PMID: 32366478.

3. Worrall LJ, Hu J, Strynadka NCJ. Aligning the Symmetry of the Type III Secretion System Needle Complex. J Chem Inf Model. 2020 May 4. doi: 10.1021/acs.jcim.0c00088. [Epub ahead of print] PubMed PMID: 32293878.

4. Kogler M, Tortola L, Negri GL, Leopoldi A, El-Naggar AM, Mereiter S, Gomez Diaz C, Nitsch R, Tortora D, Kavirayani AM, Gapp BV, Rao S, Uribesalgo I, Hoffmann D, Cikes D, Novatchkova M, Williams DA, Trent JM, Ikeda F, Daugaard M, Hagelkruys A, Sorensen PH, Penninger JM. HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases. Cancer Res. 2020 May 4. pii: canres.2270.2019. doi: 10.1158/0008-5472.CAN-19-2270. [Epub ahead of print] PubMed PMID: 32366477.

May 4, Pubcrawler Hits:

1. Post KL, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid TA, Meyers WM, Herrington C, Young BP, Callaghan DB, Rogic S, Edwards M, Niciforovic A, Cau A, Rankin CH, O'Connor TP, Bamji SX, Loewen CJR, Allan DW, Pavlidis P, Haas K. Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun. 2020 Apr 29;11(1):2073. doi: 10.1038/s41467-020-15943-0. PubMed PMID: 32350270; PubMed Central PMCID: PMC7190743.

2. Chen CH, Lai CH, Hong YK, Lu JM, Lin SY, Lee TC, Chang LY, Ho ML, Conway EM, Wu HL, Cheng TL. Thrombomodulin functional domains support osteoblast differentiation and bone healing in diabetes in mice. J Bone Miner Res. 2020 Apr 24. doi: 10.1002/jbmr.4036. [Epub ahead of print] PubMed PMID: 32329910.

3. Erwin SR, Sun W, Copeland M, Lindo S, Spruston N, Cembrowski MS. A Sparse, Spatially Biased Subtype of Mature Granule Cell Dominates Recruitment in Hippocampal-Associated Behaviors. Cell Rep. 2020 Apr 28;31(4):107551. doi: 10.1016/j.celrep.2020.107551. PubMed PMID: 32348756.

4. Monteil V, Kwon H, Prado P, Hagelkrüys A, Wimmer RA, Stahl M, Leopoldi A, Garreta E, Hurtado Del Pozo C, Prosper F, Romero JP, Wirnsberger G, Zhang H, Slutsky AS, Conder R, Montserrat N, Mirazimi A, Penninger JM. Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2. Cell. 2020 Apr 17. pii: S0092-8674(20)30399-8. doi: 10.1016/j.cell.2020.04.004. [Epub ahead of print] PubMed PMID: 32333836; PubMed Central PMCID: PMC7181998.

Apr 27, Pubcrawler Hits:

1. Jun D, Richardson-Sanchez T, Mahey A, Murphy MEP, Fernandez RC, Beatty JT. Introduction of the Menaquinone Biosynthetic Pathway into Rhodobacter sphaeroides and de Novo Synthesis of Menaquinone for Incorporation into Heterologously Expressed Integral Membrane Proteins. ACS Synth Biol. 2020 Apr 21. doi: 10.1021/acssynbio.0c00066. [Epub ahead of print] PubMed PMID: 32271543.

2. Holt C, Hamborg L, Lau K, Brohus M, Sørensen AB, Larsen KT, Sommer C, Van Petegem F, Overgaard MT, Wimmer R. The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-domain, altering its interaction with the cardiac ryanodine receptor. J Biol Chem. 2020 Apr 21. pii: jbc.RA120.013430. doi: 10.1074/jbc.RA120.013430. [Epub ahead of print] PubMed PMID: 32317284.

3. Caveney NA, Egan AJF, Ayala I, Laguri C, Robb CS, Breukink E, Vollmer W, Strynadka NCJ, Simorre JP. Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa. Structure. 2020 Apr 9. pii: S0969-2126(20)30094-0. doi: 10.1016/j.str.2020.03.012. [Epub ahead of print] PubMed PMID: 32320673.

Apr 20, Pubcrawler Hits:

1. Ramzy A, Asadi A, Kieffer TJ. Revisiting Proinsulin Processing: Evidence That Human β-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 But Not PC2. Diabetes. 2020 Apr 14. pii: db190276. doi: 10.2337/db19-0276. [Epub ahead of print] PubMed PMID: 32291281.

2. Tabernero A, Koulakoff A, Roux L, Venance L, Leybaert L, Sáez JC, Naus CC. Christian Giaume (November 1951-July 2019). Glia. 2020 Apr 16. doi: 10.1002/glia.23836. [Epub ahead of print] PubMed PMID: 32298009.

Apr 13, Pubcrawler Hits:

1. Hunter AC, Petley-Ragan LM, Das M, Auld VJ. Basigin associates with integrin in order to regulate perineurial glia and Drosophila nervous system morphology. J Neurosci. 2020 Apr 6. pii: JN-RM-1397-19. doi: 10.1523/JNEUROSCI.1397-19.2020. [Epub ahead of print] PubMed PMID: 32265259.

2. Déjean G, Tamura K, Cabrera A, Jain N, Pudlo NA, Pereira G, Viborg AH, Van Petegem F, Martens EC, Brumer H. Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides. mBio. 2020 Apr 7;11(2). pii: e00095-20. doi: 10.1128/mBio.00095-20. PubMed PMID: 32265336.

3. Lin BH, Sutherland MR, Rosell FI, Morrissey JH, Pryzdial ELG. Coagulation factor VIIa binds to herpes simplex virus 1-encoded glycoprotein C forming a factor X-enhanced tenase complex oriented on membranes. J Thromb Haemost. 2020 Jun;18(6):1370-1380. doi: 10.1111/jth.14790. Epub 2020 Apr 9. PMID: 32145149.

Apr 6, Pubcrawler Hits:

1. Jalily PH, Duncan MC, Fedida D, Wang J, Tietjen I. Put a cork in it: Plugging the M2 viral ion channel to sink influenza. Antiviral Res. 2020 Mar 27:104780. doi: 10.1016/j.antiviral.2020.104780. [Epub ahead of print] Review. PubMed PMID: 32229237; PubMed Central PMCID: PMC7102647.

2. Brind'Amour J, Lorincz MC. Setting the chromatin stage in oocytes. Nat Cell Biol. 2020 Mar 30. doi: 10.1038/s41556-020-0499-7. [Epub ahead of print] PubMed PMID: 32231308.

3. Workman SD, Strynadka NCJ. A Slippery Scaffold: Synthesis and Recycling of the Bacterial Cell Wall Carrier Lipid. J Mol Biol. 2020 Mar 28. pii: S0022-2836(20)30258-8. doi: 10.1016/j.jmb.2020.03.025. [Epub ahead of print] Review. PubMed PMID: 32234311.

Mar 30, Pubcrawler Hits:

1. Tysoe CR, Caner S, Calvert MB, Win-Mason A, Brayer GD, Withers SG. Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase. Chem Sci. 2019 Oct 18;10(48):11073-11077. doi: 10.1039/c9sc02610j. eCollection 2019 Dec 28. PubMed PMID: 32206255; PubMed Central PMCID: PMC7069248.

2. Szoták-Ajtay K, Szõke D, Kovács G, Andréka J, Brenner GB, Giricz Z, Penninger J, Kahn ML, Jakus Z. Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1 (K/K) Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth. Front Bioeng Biotechnol. 2020 Mar 6;8:136. doi: 10.3389/fbioe.2020.00136. eCollection 2020. PubMed PMID: 32211389; PubMed Central PMCID: PMC7067749.

Mar 23, Pubcrawler Hits:

1. Davies JE, Behroozian S. An ancient solution to a modern problem. Mol Microbiol. 2020 Mar;113(3):546-549. doi: 10.1111/mmi.14481. Review. PubMed PMID: 32185831.

2. Ludwig DS, Ebbeling CB, Bikman BT, Johnson JD. Testing the carbohydrate-insulin model in mice: The importance of distinguishing primary hyperinsulinemia from insulin resistance and metabolic dysfunction. Mol Metab. 2020 Feb 12:100960. doi: 10.1016/j.molmet.2020.02.003. [Epub ahead of print] PubMed PMID: 32199816.

3. Ye J, Huang A, Wang H, Zhang AMY, Huang X, Lan Q, Sato T, Goyama S, Kurokawa M, Deng C, Sander M, Schaeffer DF, Li W, Kopp JL, Xie R. PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response. Cell Death Dis. 2020 Mar 16;11(3):187. doi: 10.1038/s41419-020-2371-x. PubMed PMID: 32179733; PubMed Central PMCID: PMC7075911.

4. Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, Roberge M, Nygaard HB. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020 Mar 16;15(1):21. doi: 10.1186/s13024-020-00369-5. PubMed PMID: 32178712; PubMed Central PMCID: PMC7075020.

5. Wunderle M, Ruebner M, Häberle L, Schwenke E, Hack CC, Bayer CM, Koch MC, Schwitulla J, Schulz-Wendtland R, Kozieradzki I, Lux MP, Beckmann MW, Jud SM, Penninger JM, Schneider MO, Fasching PA. RANKL and OPG and their influence on breast volume changes during pregnancy in healthy women. Sci Rep. 2020 Mar 20;10(1):5171. doi: 10.1038/s41598-020-62070-3. PubMed PMID: 32198488.

Mar 16, Pubcrawler Hits:

1. Sin WC, Tam N, Moniz D, Lee C, Church J. Na/H exchanger NHE1 acts upstream of rho GTPases to promote neurite outgrowth. J Cell Commun Signal. 2020 Mar 6. doi: 10.1007/s12079-020-00556-5. [Epub ahead of print] PubMed PMID: 32144636.

2. Roberts ME, Barvalia M, Silva JA, Cederberg RA, Chu W, Wong A, Tai D, Chen S, Matos I, Priatel J, Cullis PR, Harder K. Deep Phenotyping by Mass Cytometry and Single Cell RNA-Sequencing Reveals LYN Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan. Circ Res. 2020 Mar 10. doi: 10.1161/CIRCRESAHA.119.315708. [Epub ahead of print] PubMed PMID: 32151196.

3. Poole AT, Sitko CA, Le C, Naus CC, Hill BM, Bushnell EAC, Chen VC. Examination of sulfonamide-based inhibitors of MMP3 using the conditioned media of invasive glioma cells. J Enzyme Inhib Med Chem. 2020 Dec;35(1):672-681. doi: 10.1080/14756366.2020.1715387. PubMed PMID: 32156166.

4. Stringer RN, Jurkovicova-Tarabova B, Huang S, Haji-Ghassemi O, Idoux R, Liashenko A, Souza IA, Rzhepetskyy Y, Lacinova L, Van Petegem F, Zamponi GW, Pamphlett R, Weiss N. A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Ca(v)3.2 T-type channel activity. Mol Brain. 2020 Mar 6;13(1):33. doi: 10.1186/s13041-020-00577-6. PubMed PMID: 32143681; PubMed Central PMCID: PMC7060640.

5. Bravo-Caparrós I, Ruiz-Cantero MC, Perazzoli G, Cronin SJF, Vela JM, Hamed MF, Penninger JM, Baeyens JM, Cobos EJ, Nieto FR. Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury. FASEB J. 2020 Mar 10. doi: 10.1096/fj.201901921R. [Epub ahead of print] PubMed PMID: 32157739.

6. Inoue M, Hada K, Shiraishi H, Yatsuka H, Fujinami H, Morisaki I, Nishida Y, Matsubara E, Ishitani T, Hanada R, Matsumoto M, Penninger JM, Ihara K, Hanada T. Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2. Biochem Biophys Res Commun. 2020 Mar 3. pii: S0006-291X(20)30448-4. doi: 10.1016/j.bbrc.2020.02.157. [Epub ahead of print] PubMed PMID: 32143824.

Mar 9, Pubcrawler Hits:

1. Gadbery JE, Round JW, Yuan T, Wipperman MF, Story KT, Crowe AM, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS. IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria. Biochemistry. 2020 Mar 4. doi: 10.1021/acs.biochem.0c00005. [Epub ahead of print] PubMed PMID: 32101684.

2. Freitas-Andrade M, Bechberger J, Wang J, Yeung KKC, Whitehead SN, Hansen RS, Naus CC. Danegaptide Enhances Astrocyte Gap Junctional Coupling and Reduces Ischemic Reperfusion Brain Injury in Mice. Biomolecules. 2020 Feb 26;10(3). pii: E353. doi: 10.3390/biom10030353. PubMed PMID: 32110860.

3. Minina EA, Staal J, Alvarez VE, Berges JA, Berman-Frank I, Beyaert R, Bidle KD, Bornancin F, Casanova M, Cazzulo JJ, Choi CJ, Coll NS, Dixit VM, Dolinar M, Fasel N, Funk C, Gallois P, Gevaert K, Gutierrez-Beltran E, Hailfinger S, Klemenčič M, Koonin EV, Krappmann D, Linusson A, Machado MFM, Madeo F, Megeney LA, Moschou PN, Mottram JC, Nyström T, Osiewacz HD, Overall CM, Pandey KC, Ruland J, Salvesen GS, Shi Y, Smertenko A, Stael S, Ståhlberg J, Suárez MF, Thome M, Tuominen H, Van Breusegem F, van der Hoorn RAL, Vardi A, Zhivotovsky B, Lam E, Bozhkov PV. Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases. Mol Cell. 2020 Mar 5;77(5):927-929. doi: 10.1016/j.molcel.2019.12.020. PubMed PMID: 32142688.

4. Sahile HA, Rens C, Shapira T, Andersen RJ, Av-Gay Y. DMN-Tre Labeling for Detection and High-Content Screening of Compounds against Intracellular Mycobacteria. ACS Omega. 2020 Feb 14;5(7):3661-3669. doi: 10.1021/acsomega.9b04173. eCollection 2020 Feb 25. PubMed PMID: 32118181; PubMed Central PMCID: PMC7045496.

5. Zhang H, Penninger JM, Li Y, Zhong N, Slutsky AS. Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive Care Med. 2020 Mar 3. doi: 10.1007/s00134-020-05985-9. [Epub ahead of print] PubMed PMID: 32125455.

Mar 2, Pubcrawler Hits:

1. Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, Chan FC, Chong L, Abraham L, Kridel R, Boyle M, Meissner B, Aoki T, Takata K, Woolcock BW, Viganò E, Gold M, Molday LL, Molday RS, Telenius A, Li MY, Wretham N, Dos Santos N, Wong M, Viller NN, Uger RA, Duns G, Baticados A, Madero A, Bristow BN, Farinha P, Slack GW, Ben-Neriah S, Lai D, Zhang AW, Salehi S, Shulha HP, Chiu DS, Mostafavi S, Gerrie AS, Huang DW, Rushton C, Villa D, Sehn LH, Savage KJ, Mungall AJ, Weng AP, Bally MB, Morin RD, Cohen Freue GV, Staudt LM, Connors JM, Marra MA, Shah SP, Gascoyne RD, Scott DW, Steidl C. TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma. Nat Med. 2020 Feb 24. doi: 10.1038/s41591-020-0757-z. [Epub ahead of print] PubMed PMID: 32094924.

2. Dong Y, Arif AA, Guo J, Ha Z, Lee-Sayer SSM, Poon GFT, Dosanjh M, Roskelley CD, Huan T, Johnson P. CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation. Front Immunol. 2020 Jan 30;11:29. doi: 10.3389/fimmu.2020.00029. eCollection 2020. PubMed PMID: 32082314; PubMed Central PMCID: PMC7002364.

3. Hu CK, Wang W, Brind'Amour J, Singh PP, Reeves GA, Lorincz MC, Alvarado AS, Brunet A. Vertebrate diapause preserves organisms long term through Polycomb complex members. Science. 2020 Feb 21;367(6480):870-874. doi: 10.1126/science.aaw2601. PubMed PMID: 32079766.

4. Minato T, Nirasawa S, Sato T, Yamaguchi T, Hoshizaki M, Inagaki T, Nakahara K, Yoshihashi T, Ozawa R, Yokota S, Natsui M, Koyota S, Yoshiya T, Yoshizawa-Kumagaye K, Motoyama S, Gotoh T, Nakaoka Y, Penninger JM, Watanabe H, Imai Y, Takahashi S, Kuba K. B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction. Nat Commun. 2020 Feb 26;11(1):1058. doi: 10.1038/s41467-020-14867-z. PubMed PMID: 32103002.

5. Fujinami H, Shiraishi H, Hada K, Inoue M, Morisaki I, Higa R, Shin T, Kobayashi T, Hanada R, Penninger JM, Mimata H, Hanada T. CLP1 acts as the main RNA kinase in mice. Biochem Biophys Res Commun. 2020 Feb 17. pii: S0006-291X(20)30334-X. doi: 10.1016/j.bbrc.2020.02.066. [Epub ahead of print] PubMed PMID: 32081435.

Feb 24, Pubcrawler Hits:

1. Anwar MA, Barrera-Machuca AA, Calderon N, Wang W, Tausan D, Vayali T, Wishart D, Cullis P, Fraser R. Value-based healthcare delivery through metabolomics-based personalized health platform. Healthc Manage Forum. 2020 Feb 20:840470420904733. doi: 10.1177/0840470420904733. [Epub ahead of print] PubMed PMID: 32077764.

2. Alhasan MM, Cait AM, Heimesaat MM, Blaut M, Klopfleisch R, Wedel A, Conlon TM, Yildirim AÖ, Sodemann EB, Mohn WW, Bereswill S, Conrad ML. Antibiotic use during pregnancy increases offspring asthma severity in a dose dependent manner. Allergy. 2020 Feb 16. doi: 10.1111/all.14234. [Epub ahead of print] PubMed PMID: 32064643.

Feb 17, Pubcrawler Hits:

1. Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, Ostenson CG, Kieffer TJ, Banks K, Pessin JE, Gaisano HY. SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes. JCI Insight. 2020 Feb 13;5(3). pii: 129694. doi: 10.1172/jci.insight.129694. PubMed PMID: 32051343.

2. Price HR, Chehroudi C, Knight SJ, Smith AD, Lai D, Kim H, Wright TE, Coughtrie MW, Collier AC. Umbilical cord as an analytical matrix - A technical note. Placenta. 2020 Jan 15;90:42-44. doi: 10.1016/j.placenta.2019.12.001. Epub 2019 Dec 3. PubMed PMID: 32056550.

Feb 10, Pubcrawler Hits:

1. Panwar P, Hedtke T, Heinz A, Andrault PM, Hoehenwarter W, Granville DJ, Schmelzer CEH, Brömme D. Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation. Biochim Biophys Acta Gen Subj. 2020 Jan 30:129544. doi: 10.1016/j.bbagen.2020.129544. [Epub ahead of print] PubMed PMID: 32007579.

2. Elisia I, Lam V, Cho B, Hay M, Li MY, Kapeluto J, Elliott T, Harris D, Bu L, Jia W, Leung H, Mohn W, Krystal G. Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk. PLoS One. 2020 Feb 6;15(2):e0228633. doi: 10.1371/journal.pone.0228633. eCollection 2020. PubMed PMID: 32027700.

3. Wang K, Brohus M, Holt C, Overgaard MT, Wimmer R, Van Petegem F. Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca(2+) binding and cause misfolding. J Physiol. 2020 Feb 3. doi: 10.1113/JP279307. [Epub ahead of print] PubMed PMID: 32012279.

4. Beveridge R, Stadlmann J, Penninger JM, Mechtler K. A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes. Nat Commun. 2020 Feb 6;11(1):742. doi: 10.1038/s41467-020-14608-2. PubMed PMID: 32029734.

Feb 3, Pubcrawler Hits:

1. Tung M, Van Petegem F, Lauson S, Collier A, Hodgkinson K, Fernandez B, Connors S, Leather R, Sanatani S, Arbour L. Cardiac arrest in a mother and daughter and the identification of a novel RYR2 variant, predisposing to low penetrant catecholaminergic polymorphic ventricular tachycardia in a four-generation Canadian family. Mol Genet Genomic Med. 2020 Jan 28:e1151. doi: 10.1002/mgg3.1151. [Epub ahead of print] PubMed PMID: 31994352.

2. Gardill B, Huang J, Tu L, Van Petegem F, Oxenoid K, Thomson CA. Nanodisc technology facilitates identification of monoclonal antibodies targeting multi-pass membrane proteins. Sci Rep. 2020 Jan 24;10(1):1130. doi: 10.1038/s41598-020-58002-w. PubMed PMID: 31980674; PubMed Central PMCID: PMC6981118.

3. Bodnar TS, Raineki C, Wertelecki W, Yevtushok L, Plotka L, Granovska I, Zymak-Zakutnya N, Pashtepa A, Wells A, Honerkamp-Smith G, Coles CD, Kable JA, Chambers CD, Weinberg J; and the CIFASD. Immune network dysregulation associated with child neurodevelopmental delay: modulatory role of prenatal alcohol exposure. J Neuroinflammation. 2020 Jan 28;17(1):39. doi: 10.1186/s12974-020-1717-8. PubMed PMID: 31992316.

4. Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin SJF, Sun Y, Zhang Y, Xie C, Rodriguez J, Zhou K, Hagberg H, Mallard C, Wang X, Penninger JM, Kroemer G, Blomgren K, Zhu C. Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell Death Dis. 2020 Jan 30;11(1):77. doi: 10.1038/s41419-020-2280-z. PubMed PMID: 32001673; PubMed Central PMCID: PMC6992638.

Jan 27, Pubcrawler Hits:

1. Pourrier M, Fedida D. The Emergence of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs) as a Platform to Model Arrhythmogenic Diseases. Int J Mol Sci. 2020 Jan 19;21(2). pii: E657. doi: 10.3390/ijms21020657. Review. PubMed PMID: 31963859.

2. Pournia F, Dang-Lawson M, Choi K, Mo V, Lampe PD, Matsuuchi L. Identification of serine residues in the Connexin43 carboxyl tail important for BCR-mediated spreading of B-lymphocytes. J Cell Sci. 2020 Jan 21. pii: jcs.237925. doi: 10.1242/jcs.237925. [Epub ahead of print] PubMed PMID: 31964709.

3. Charabati M, Donkers SJ, Kirkland MC, Osborne LC. A critical analysis of helminth immunotherapy in multiple sclerosis. Mult Scler. 2020 Jan 23:1352458519899040. doi: 10.1177/1352458519899040. [Epub ahead of print] PubMed PMID: 31971074.

4. Wat LW, Chao C, Bartlett R, Buchanan JL, Millington JW, Chih HJ, Chowdhury ZS, Biswas P, Huang V, Shin LJ, Wang LC, Gauthier ML, Barone MC, Montooth KL, Welte MA, Rideout EJ. A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown. PLoS Biol. 2020 Jan 21;18(1):e3000595. doi: 10.1371/journal.pbio.3000595. [Epub ahead of print] PubMed PMID: 31961851.

5. Li FKK, Rosell FI, Gale RT, Simorre JP, Brown ED, Strynadka NCJ. Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase. J Biol Chem. 2020 Jan 22. pii: jbc.RA119.011469. doi: 10.1074/jbc.RA119.011469. [Epub ahead of print] PubMed PMID: 31969390.

6. Gil KN, Lillie MA, Vogl AW, Shadwick RE. Rorqual whale nasal plugs: protecting the respiratory tract against water entry and barotrauma. J Exp Biol. 2020 Jan 23. pii: jeb.219691. doi: 10.1242/jeb.219691. [Epub ahead of print] PubMed PMID: 31974219.

7. Dhanda AS, Yu C, Lulic KT, Vogl AW, Rausch V, Yang D, Nichols BJ, Kim SH, Polo S, Hansen CG, Guttman JA. Listeria monocytogenes Exploits Host Caveolin for Cell-to-Cell Spreading. mBio. 2020 Jan 21;11(1). pii: e02857-19. doi: 10.1128/mBio.02857-19. PubMed PMID: 31964732.

Jan 20, Pubcrawler Hits:

1. Sheikh A, Abraham N. Interleukin-7 Receptor Alpha in Innate Lymphoid Cells: More Than a Marker. Front Immunol. 2019 Dec 11;10:2897. doi: 10.3389/fimmu.2019.02897. eCollection 2019. Review. PubMed PMID: 31921158; PubMed Central PMCID: PMC6917604.

2. Shin JJH, Liu P, Chan LJ, Ullah A, Pan J, Borchers CH, Burke JE, Stefan C, Smits GJ, Loewen CJR. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. Dev Cell. 2020 Jan 9. pii: S1534-5807(19)31031-7. doi: 10.1016/j.devcel.2019.12.010. [Epub ahead of print] PubMed PMID: 31928972.

3. Findlay Black H, Mastromatteo S, Sinha S, Ehrlich RL, Nislow C, Chang Mell J, Redfield RJ. A competence-regulated toxin-antitoxin system in Haemophilus influenzae. PLoS One. 2020 Jan 13;15(1):e0217255. doi: 10.1371/journal.pone.0217255. eCollection 2020. PubMed PMID: 31931516.

Jan 13, Pubcrawler Hits:

1. Asghari P, Scriven DR, Ng M, Panwar P, Chou KC, van Petegem F, Moore ED. Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification. Elife. 2020 Jan 9;9. pii: e51602. doi: 10.7554/eLife.51602. [Epub ahead of print] PubMed PMID: 31916935.

2. Indira Chandran V, Mansson AS, Barbachowska M, Cerezo-Magana M, Nodin B, Joshi B, Koppada N, Saad OM, Gluz O, Isaksson K, Borgquist S, Jirstrom K, Nabi IR, Jernstrom H, Belting M. Hypoxia attenuates trastuzumab uptake and trastuzumab-emtansine (T-DM1) cytotoxicity through redistribution of phosphorylated caveolin-1. Mol Cancer Res. 2020 Jan 3. pii: molcanres.0856.2019. doi: 10.1158/1541-7786.MCR-19-0856. [Epub ahead of print] PubMed PMID: 31900313.

Jan 6, Pubcrawler Hits:

1. Durrer C, McKelvey S, Singer J, Batterham AM, Johnson JD, Wortman J, Little JP. Pharmacist-led therapeutic carbohydrate restriction as a treatment strategy for type 2 diabetes: the Pharm-TCR randomized controlled trial protocol. Trials. 2019 Dec 27;20(1):781. doi: 10.1186/s13063-019-3873-7. PubMed PMID: 31881991; PubMed Central PMCID: PMC6935079.

2. Jaraíz-Rodríguez M, Talaverón R, García-Vicente L, Pelaz SG, Domínguez-Prieto M, Álvarez-Vázquez A, Flores-Hernández R, Sin WC, Bechberger J, Medina JM, Naus CC, Tabernero A. Connexin43 peptide, TAT-Cx43266-283, selectively targets glioma cells, impairs malignant growth and enhances survival in mouse models in vivo. Neuro Oncol. 2019 Dec 28. pii: noz243. doi: 10.1093/neuonc/noz243. [Epub ahead of print] PubMed PMID: 31883012.


Dec 23, Pubcrawler Hits:

1. Nappi L, Aguda AH, Nakouzi NA, Lelj-Garolla B, Beraldi E, Lallous N, Thi M, Moore S, Fazli L, Battsogt D, Stoffeliene S, Ban F, Nguyen NT, Saxena N, Dueva E, Zhang F, Yamazaki T, Zoubeidi A, Cherkasov A, Brayer GD, Gleave M. Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models. J Clin Invest. 2019 Dec 17. pii: 130819. doi: 10.1172/JCI130819. [Epub ahead of print] PubMed PMID: 31845908.

2. Andrault PM, Panwar P, Brömme D. Characterization of Cathepsin S exosites that govern its elastolytic activity. Biochem J. 2019 Dec 20. pii: BCJ20190847. doi: 10.1042/BCJ20190847. [Epub ahead of print] PubMed PMID: 31860022.

3. Round P, Das S, Wu TS, Wähälä K, Van Petegem F, Hammond GL. Molecular interactions between sex hormone-binding globulin and non-steroidal ligands that enhance androgen action. J Biol Chem. 2019 Dec 18. pii: jbc.RA119.011051. doi: 10.1074/jbc.RA119.011051. [Epub ahead of print] PubMed PMID: 31852737.

4. Herrmann J, Li PN, Jabbarpour F, Chan ACK, Rajkovic I, Matsui T, Shapiro L, Smit J, Weiss TM, Murphy MEP, Wakatsuki S. A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proc Natl Acad Sci U S A. 2019 Dec 17. pii: 201909798. doi: 10.1073/pnas.1909798116. [Epub ahead of print] PubMed PMID: 31848245.

5. Hsu CR, Xiong R, Sugioka K. In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads. J Vis Exp. 2019 Nov 26;(153). doi: 10.3791/60422. PubMed PMID: 31840666.

Dec 16, Pubcrawler Hits:

1. Bogutz AB, Brind'Amour J, Kobayashi H, Jensen KN, Nakabayashi K, Imai H, Lorincz MC, Lefebvre L. Evolution of imprinting via lineage-specific insertion of retroviral promoters. Nat Commun. 2019 Dec 12;10(1):5674. doi: 10.1038/s41467-019-13662-9. PubMed PMID: 31831741.

2. Hu J, Worrall LJ, Strynadka NC. Towards capture of dynamic assembly and action of the T3SS at near atomic resolution. Curr Opin Struct Biol. 2019 Dec 7;61:71-78. doi: 10.1016/ [Epub ahead of print] Review. PubMed PMID: 31821956.

Dec 9, Pubcrawler Hits:

1. Thompson KJ, Kenward PA, Bauer KW, Warchola T, Gauger T, Martinez R, Simister RL, Michiels CC, Llirós M, Reinhard CT, Kappler A, Konhauser KO, Crowe SA. Photoferrotrophy, deposition of banded iron formations, and methane production in Archean oceans. Sci Adv. 2019 Nov 27;5(11):eaav2869. doi: 10.1126/sciadv.aav2869. eCollection 2019 Nov. PubMed PMID: 31807693; PubMed Central PMCID: PMC6881150.

2. Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, Kulkarni JA, van der Meel R, Cullis PR. The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs. Nat Nanotechnol. 2019 Dec;14(12):1084-1087. doi: 10.1038/s41565-019-0591-y. PubMed PMID: 31802031.

3. Yazer MH, Spinella PC, Doyle L, Kaufman RM, Dunn R, Hess JR, Filho LA, Fontaine M, Gathof B, Jackson B, Murphy MF, Pasion J, Raval JS, Rosinski K, Seheult J, Shih AW, Sperry J, Staves J, Tuott EE, Ziman A, Triulzi DJ, McKenna D, Stroncek D, Fung M, Tinmouth A, Devine D, Cardigan R, Vassallo R, Germain M, Reems J, Garritsen H, Takanashi M, Stanworth S, Delaney M, Cancelas J, Meer PV, Marks D, Cohn C, Shaz B, Tiberghien P, Goldman M, Girdlestone J, Pati S, Schäfer R, Schwartz JY, Dunbar N, Pagano M, So-Osman C, Noorman F, Apelseth TO, Kanias T, Stolla M, Angelantonio ED, Hurk KVD, Steele WR, Erikstrup C, Merz EM; Biomedical Excellence for Safer Transfusion Collaborative; Appendix. Members of the Biomedical Excellence for Safer Transfusion Collaborative. Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere with Most ABO Typings. Anesthesiology. 2019 Nov 25. doi: 10.1097/ALN.0000000000003069. [Epub ahead of print] PubMed PMID: 31789634.

4. Lu M, Mizumoto K. Gradient-independent Wnt signaling instructs asymmetric neurite pruning in C. elegans. Elife. 2019 Dec 5;8. pii: e50583. doi: 10.7554/eLife.50583. PubMed PMID: 31804181; PubMed Central PMCID: PMC6894928.

5. Paik YK, Overall CM, Corrales F, Deutsch EW, Lane L, Omenn GS. Advances in Identifying and Characterizing the Human Proteome. J Proteome Res. 2019 Dec 6;18(12):4079-4084. doi: 10.1021/acs.jproteome.9b00745. PubMed PMID: 31805768.

6. Fallata AM, Wyatt RA, Levesque JM, Dufour A, Overall CM, Crawford BD. Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance. Biomedicines. 2019 Nov 29;7(4). pii: E93. doi: 10.3390/biomedicines7040093. PubMed PMID: 31795436.

7. Van Petegem F, Gardill BR. Reply to Pitt and Lee: Occupancies of Ca(2+) in complexes of calmodulin with voltage-gated sodium channels. Proc Natl Acad Sci U S A. 2019 Dec 3. pii: 201918159. doi: 10.1073/pnas.1918159116. [Epub ahead of print] PubMed PMID: 31796598.

8. Islamzada E, Matthews K, Guo Q, Santoso AT, Duffy SP, Scott MD, Ma H. Deformability based sorting of stored red blood cells reveals donor-dependent aging curves. Lab Chip. 2019 Dec 4. doi: 10.1039/c9lc01058k. [Epub ahead of print] PubMed PMID: 31796943.

Dec 2, Pubcrawler Hits:

1. Bray MS, Wu J, Padilla CC, Stewart FJ, Fowle DA, Henny C, Simister RL, Thompson KJ, Crowe SA, Glass JB. Phylogenetic and structural diversity of aromatically dense pili from environmental metagenomes. Environ Microbiol Rep. 2019 Nov 7. doi: 10.1111/1758-2229.12809. [Epub ahead of print] PubMed PMID: 31701641.

2. McDiarmid TA, Belmadani M, Liang J, Meili F, Mathews EA, Mullen GP, Hendi A, Wong WR, Rand JB, Mizumoto K, Haas K, Pavlidis P, Rankin CH. Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation. Proc Natl Acad Sci U S A. 2019 Nov 21. pii: 201912049. doi: 10.1073/pnas.1912049116. [Epub ahead of print] PubMed PMID: 31754030.

3. Jobin PG, Solis N, Machado Y, Bell PA, Rai SK, Kwon NH, Kim S, Overall CM, Butler GS. Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. J Biol Chem. 2019 Nov 26. pii: jbc.RA119.010486. doi: 10.1074/jbc.RA119.010486. [Epub ahead of print] PubMed PMID: 31771979.

Nov 25, Pubcrawler Hits:

1. Shimell JJ, Shah BS, Cain SM, Thouta S, Kuhlmann N, Tatarnikov I, Jovellar DB, Brigidi GS, Kass J, Milnerwood AJ, Snutch TP, Bamji SX. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation. Cell Rep. 2019 Nov 19;29(8):2422-2437.e8. doi: 10.1016/j.celrep.2019.10.065. PubMed PMID: 31747610.

2. Fenninger F, Han J, Stanwood SR, Nohara LL, Arora H, Choi KB, Munro L, Pfeifer CG, Shanina I, Horwitz MS, Jefferies WA. Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction. Front Immunol. 2019 Oct 29;10:2473. doi: 10.3389/fimmu.2019.02473. eCollection 2019. PubMed PMID: 31736943; PubMed Central PMCID: PMC6833481.

3. Cronin SJF, Woolf CJ, Weiss G, Penninger JM. The Role of Iron Regulation in Immunometabolism and Immune-Related Disease. Front Mol Biosci. 2019 Nov 22;6:116. doi: 10.3389/fmolb.2019.00116. eCollection 2019. Review. PubMed PMID: 31824960; PubMed Central PMCID: PMC6883604.

Nov 18, Pubcrawler Hits:

1. Li L, Chen B, Zhu R, Li R, Tian Y, Liu C, Jia Q, Wang L, Tang J, Zhao D, Mo F, Liu Y, Li Y, Orekhov AN, Brömme D, Zhang D, Gao S. Fructus Ligustri Lucidi preserves bone quality through the regulation of gut microbiota diversity, oxidative stress, TMAO and Sirt6 levels in aging mice. Aging (Albany NY). 2019 Nov 12;11. doi: 10.18632/aging.102376. [Epub ahead of print] PubMed PMID: 31715585.

2. Kulkarni JA, Witzigmann D, Leung J, Tam YYC, Cullis PR. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 12. doi: 10.1039/c9nr09347h. [Epub ahead of print] PubMed PMID: 31713568.

3. Holert J, Brown K, Hashimi A, Eltis LD, Mohn WW. Steryl ester formation and accumulation in steroid-degrading bacteria. Appl Environ Microbiol. 2019 Nov 8. pii: AEM.02353-19. doi: 10.1128/AEM.02353-19. [Epub ahead of print] PubMed PMID: 31704679.

4. Wang Y, Eldstrom J, Fedida D. The IKs ion channel activator, mefenamic acid, requires KCNE1 and modulates channel gating in a subunit-dependent manner. Mol Pharmacol. 2019 Nov 13. pii: mol.119.117952. doi: 10.1124/mol.119.117952. [Epub ahead of print] PubMed PMID: 31722973.

5. Novales Flamarique I, Sayed Ahmed A, Cheng CL, Molday RS, Devlin RH. Growth hormone regulates opsin expression in the retina of a salmonid fish. J Neuroendocrinol. 2019 Oct 20:e12804. doi: 10.1111/jne.12804. [Epub ahead of print] PubMed PMID: 31630448.

Nov 11, Pubcrawler Hits:

1. Posynick BJ, Brown CJ. Escape From X-Chromosome Inactivation: An Evolutionary Perspective. Front Cell Dev Biol. 2019 Oct 22;7:241. doi: 10.3389/fcell.2019.00241. eCollection 2019. Review. PubMed PMID: 31696116; PubMed Central PMCID: PMC6817483.

2. Urtatiz O, Cook C, Huang JL, Yeh I, Van Raamsdonk CD. GNAQ(Q209L) expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. Pigment Cell Melanoma Res. 2019 Nov 4. doi: 10.1111/pcmr.12843. [Epub ahead of print] PubMed PMID: 31680437.

3. Ding H, Grüll MP, Mulligan ME, Lang AS, Beatty JT. Induction of Rhodobacter capsulatus Gene Transfer Agent Gene Expression Is a Bistable Stochastic Process Repressed by an Extracellular Calcium-Binding RTX Protein Homologue. J Bacteriol. 2019 Nov 5;201(23):e00430-19. doi: 10.1128/JB.00430-19. PMID: 31501287; PMCID: PMC6832060.

Nov 4, Pubcrawler Hits:

1. Stadlmann J, Hudecz O, Krššáková G, Ctortecka C, Van Raemdonck G, Op De Beeck J, Desmet G, Penninger JM, Jacobs P, Mechtler K. Improved Sensitivity in Low-Input Proteomics Using Micropillar Array-Based Chromatography. Anal Chem. 2019 Oct 31. doi: 10.1021/acs.analchem.9b02899. [Epub ahead of print] PubMed PMID: 31612716.

Oct 28, Pubcrawler Hits:

1. Deutsch EW, Lane L, Overall CM, Bandeira N, Baker MS, Pineau C, Moritz RL, Corrales F, Orchard S, Van Eyk JE, Paik YK, Weintraub ST, Vandenbrouck Y, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0.  J Proteome Res. 2019 Oct 21. doi: 10.1021/acs.jproteome.9b00542. [Epub ahead of print] PubMed PMID: 31599596.

2. Richter A, Shapira T, Av-Gay Y. THP-1 and Dictyostelium infection models for screening and characterization of anti-Mycobacterium abscessus hit compounds. Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.01601-19. doi: 10.1128/AAC.01601-19. [Epub ahead of print] PubMed PMID: 31636068.

Oct 21, Pubcrawler Hits:

1. Vardaki M, Devine D, Serrano K, Simantiris N, Blades M, Piret JM, Turner R. Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy (SORS) Device. Appl Spectrosc. 2019 Oct 16:3702819884625. doi: 10.1177/0003702819884625. [Epub ahead of print] PubMed PMID: 31617382.

2. Solis N, Parambath A, Abbina S, Kizhakkedathu J, Overall CM. Simplified high yield TAILS terminomics using a new HPG-ALD 800K-2000 polymer with precipitation. Methods Enzymol. 2019; 626:429-446. doi: 10.1016/bs.mie.2019.07.030. Epub 2019 Aug 13. PubMed PMID: 31606086.

3. Guissart C, Harrison AN, Benkirane M, Oncel I, Arslan EA, Chassevent AK, Baraῆano K, Larrieu L, Iascone M, Tenconi R, Claustres M, Eroglu-Ertugrul N, Calvas P, Topaloglu H, Molday RS, Koenig M. ATP8A2-related disorders as recessive cerebellar ataxia. J Neurol. 2019 Oct 14. doi: 10.1007/s00415-019-09579-4. [Epub ahead of print] PubMed PMID: 31612321.

4. Kurata T, Rajendran V, Fan S, Ohta T, Numata M, Fushida S. NHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cells. Clin Exp Metastasis. 2019 Oct 8. doi: 10.1007/s10585-019-10001-6. [Epub ahead of print] PubMed PMID: 31595389.

5. Fons JM, Gaete M, Zahradnicek O, Landova M, Bandali H, Khannoon ER, Richman JM, Buchtova M, Tucker AS. Getting out of an egg: Merging of tooth germs to create an egg tooth in the snake. Dev Dyn. 2019 Oct 6. doi: 10.1002/dvdy.120. [Epub ahead of print] PubMed PMID: 31587402.

6. Hamada K, Omura N, Taguchi A, Baradaran-Heravi A, Kotake M, Arai M, Takayama K, Taniguchi A, Roberge M, Hayashi Y. New Negamycin-Based Potent Readthrough Derivative Effective against TGA-Type Nonsense Mutations. ACS Med Chem Lett. 2019 Sep 23; 10(10):1450-1456. doi: 10.1021/acsmedchemlett.9b00273. eCollection 2019 Oct 10. PubMed PMID: 31620232; PubMed Central PMCID: PMC6792177.

7. Taha M, Kyluik-Price D, Kumaran D, Scott MD, Toyofuku W, Ramirez-Arcos S. Bacterial survival in whole blood depends on plasma sensitivity and resistance to neutrophil killing. Transfusion. 2019 Oct 13. doi: 10.1111/trf.15550. [Epub ahead of print] PubMed PMID: 31608457.

8. Hashemi P, Sadowski I. Diversity of small molecule HIV-1 latency reversing agents identified in low- and high-throughput small molecule screens. Med Res Rev. 2020 May;40(3):881-908. doi: 10.1002/med.21638. Epub 2019 Oct 13. PMID: 31608481; PMCID: PMC7216841.

Sep 30, Pubcrawler Hits:

1. Kim H, Conway EM. Platelets and Complement Cross-Talk in Early Atherogenesis. Front Cardiovasc Med. 2019 Sep 6;6:131. doi: 10.3389/fcvm.2019.00131. eCollection 2019. Review. PubMed PMID: 31555668; PubMed Central PMCID: PMC6742699.

2. Wimmer RA, Leopoldi A, Aichinger M, Kerjaschki D, Penninger JM. Generation of blood vessel organoids from human pluripotent stem cells. Nat Protoc. 2019 Sep 25. doi: 10.1038/s41596-019-0213-z. [Epub ahead of print] PubMed PMID: 31554955.

Sep 23, Pubcrawler Hits:

1. Rahfeld P, Wardman JF, Mehr K, Huff D, Morgan-Lang C, Chen HM, Hallam SJ, Withers SG. Prospecting for α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase. J Biol Chem. 2019 Sep 17. pii: jbc.RA119.010628. doi: 10.1074/jbc.RA119.010628. [Epub ahead of print] PubMed PMID: 31530641.

2. Chehroudi C, Kim H, Wright TE, Collier AC. Dysregulation of inflammatory cytokines and inhibition of VEGFA in the human umbilical cord are associated with negative pregnancy outcomes. Placenta. 2019 Sep 3;87:16-22. doi: 10.1016/j.placenta.2019.09.002. [Epub ahead of print] PubMed PMID: 31525711.

3. Lyons BJE, Strynadka NCJ. On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome. Medchemcomm. 2019 Jun 20;10(8):1273-1289. doi: 10.1039/c9md00146h. eCollection 2019 Aug 1. Review. PubMed PMID: 31534650; PubMed Central PMCID: PMC6748289.

4. Van Petegem F. Slaying a giant: Structures of calmodulin and protein kinase a bound to the cardiac ryanodine receptor. Cell Calcium. 2019 Sep 6; 83:102079. doi: 10.1016/j.ceca.2019.102079. [Epub ahead of print] PubMed PMID: 31522075.

Sep 16, Pubcrawler Hits:

1. Ding H, Grüll MP, Mulligan ME, Lang AS, Beatty JT. Induction of Rhodobacter capsulatus gene transfer agent (RcGTA) gene expression is a bistable stochastic process repressed by an extracellular calcium-binding RTX protein homologue. J Bacteriol. 2019 Sep 9. pii: JB.00430-19. doi: 10.1128/JB.00430-19. [Epub ahead of print] PubMed PMID: 31501287.

2. Zhang W, Böttger R, Qin Z, Kulkarni JA, Vogler J, Cullis PR, Li SD. Phospholipid-Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver. Small. 2019 Sep 6:e1901782. doi: 10.1002/smll.201901782. [Epub ahead of print] PubMed PMID: 31490617.

Sep 09, Pubcrawler Hits:

1. Ng LCT, Zhuang M, Van Petegem F, Li YX, Accili EA. Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide-gated ion channel. J Gen Physiol. 2019 Sep 3. pii: jgp.201812162. doi: 10.1085/jgp.201812162. [Epub ahead of print] PubMed PMID: 31481514.

2. Forde ON, Cahill AG, Mayer KU, Mayer B, Simister RL, Finke N, Crowe SA, Cherry JA, Parker BL. Hydro-biogeochemical impacts of fugitive methane on a shallow unconfined aquifer. Sci Total Environ. 2019 Nov 10;690:1342-1354. doi: 10.1016/j.scitotenv.2019.06.322. Epub 2019 Jun 30. PubMed PMID: 31470496.

3. Levy-Booth DJ, Fetherolf MM, Stewart GR, Liu J, Eltis LD, Mohn WW. Catabolism of Alkylphenols in Rhodococcus via a Meta-Cleavage Pathway Associated With Genomic Islands. Front Microbiol. 2019 Aug 20;10:1862. doi: 10.3389/fmicb.2019.01862. eCollection 2019. PubMed PMID: 31481940; PubMed Central PMCID: PMC6710988.

4. Chen KTJ, Anantha M, Leung AWY, Kulkarni JA, Militao GGC, Wehbe M, Sutherland B, Cullis PR, Bally MB. Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use. Drug Deliv Transl Res. 2019 Sep 3. doi: 10.1007/s13346-019-00674-7. [Epub ahead of print] PubMed PMID: 31482519.

Sep 02, Pubcrawler Hits:

1. Sharifkhodaei Z, Gilbert MM, Auld VJ. Scribble and Discs-large mediate tricellular junction formation. Development. 2019 Aug 23. pii: dev.174763. doi: 10.1242/dev.174763. [Epub ahead of print] PubMed PMID: 31444218.

2. Noël G, Tham DKL, MacVicar BA, Moukhles H. Agrin plays a major role in the coalescence of the AQP4 clusters induced by gamma-1-containing laminin. J Comp Neurol. 2019 Aug 27. doi: 10.1002/cne.24763. [Epub ahead of print] PubMed PMID: 31454080.

3. Khater IM, Aroca-Ouellette ST, Meng F, Nabi IR, Hamarneh G. Caveolae and scaffold detection from single molecule localization microscopy data using deep learning. PLoS One. 2019 Aug 26;14(8):e0211659. doi: 10.1371/journal.pone.0211659. eCollection 2019. PubMed PMID: 31449531.

Aug 26, Pubcrawler Hits:

1. Conway EM. Thrombin: Coagulation's master regulator of innate immunity. J Thromb Haemost. 2019 Aug 20. doi: 10.1111/jth.14586. [Epub ahead of print] PubMed PMID: 31429203.

2. Gordon MH, Anowai A, Young D, Das N, Campden RI, Sekhon H, Myers Z, Mainoli B, Chopra S, Thuy-Boun PS, Kizhakkedathu J, Bindra G, Jijon HB, Heitman S, Yates R, Wolan DW, Edgington-Mitchell LE, MacNaughton WK, Dufour A. N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis. ACS Chem Biol. 2019 Aug 21. doi: 10.1021/acschembio.9b00608. [Epub ahead of print] PubMed PMID: 31393699.

3. Sadr Karimi S, Pante N. Carbon nanotubes as molecular transporters to study a new mechanism for molecular entry into the cell nucleus using actin polymerization force. PLoS One. 2019 Aug 22;14(8):e0221562. doi: 10.1371/journal.pone.0221562. eCollection 2019. PubMed PMID: 31437229.

4. Jakubovics N, Richman J. JDR Historical Highlights #10. J Dent Res. 2019 Sep;98(10):1063-1065. doi: 10.1177/0022034519864885. PubMed PMID: 31429667.

5. Hu J, Worrall LJ, Vuckovic M, Hong C, Deng W, Atkinson CE, Brett Finlay B, Yu Z, Strynadka NCJ. T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly. Nat Microbiol. 2019 Aug 19. doi: 10.1038/s41564-019-0545-z. [Epub ahead of print] PubMed PMID: 31427728.

Aug 19, Pubcrawler Hits:

1. Marshall EA, Stewart GL, Sage AP, Lam WL, Brown CJ. Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge. PLoS One. 2019 Aug 16;14(8):e0221371. doi: 10.1371/journal.pone.0221371. eCollection 2019. PubMed PMID: 31419261.

2. Kulkarni JA, Witzigmann D, Chen S, Cullis PR, van der Meel R. Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics. Acc Chem Res. 2019 Aug 9. doi: 10.1021/acs.accounts.9b00368. [Epub ahead of print] PubMed PMID: 31397996.

3. Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV. Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood. Transfusion. 2019 Aug 13. doi: 10.1111/trf.15485. [Epub ahead of print] PubMed PMID: 31408208.

4. Hanson PJ, Hossain AR, Qiu Y, Zhang HM, Zhao G, Li C, Lin V, Sulaimon S, Vlok M, Fung G, Chen VH, Jan E, McManus BM, Granville DJ, Yang D. Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection. Front Cell Infect Microbiol. 2019 Jul 24;9:265. doi: 10.3389/fcimb.2019.00265. eCollection 2019. PubMed PMID: 31396490; PubMed Central PMCID: PMC6667557.

5. Shi H, Strogantsev R, Takahashi N, Kazachenka A, Lorincz MC, Hemberger M, Ferguson-Smith AC. ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains. Epigenetics Chromatin. 2019 Aug 9; 12(1):49. doi: 10.1186/s13072-019-0295-4. PubMed PMID: 31399135; PubMed Central PMCID: PMC6688207.

6. Dyka FM, Molday LL, Chiodo V, Molday RS, Hauswirth WW. Dual ABCA4-AAV vector treatment reduces pathogenic retinal A2E accumulation in a mouse model of autosomal recessive Stargardt Disease. Hum Gene Ther. 2019 Aug 16. doi: 10.1089/hum.2019.132. [Epub ahead of print] PubMed PMID: 31418294.

7. Choi H, Andersen JP, Molday RS. Expression and Functional Characterization of Missense Mutations in ATP8A2 Linked to Severe Neurological Disorders. Hum Mutat. 2019 Aug 9. doi: 10.1002/humu.23889. [Epub ahead of print] PubMed PMID: 31397519.

8. Mellor GJ, Panwar P, Lee AK, Steinberg C, Hathaway JA, Bartels K, Christian S, Balaji S, Roberts JD, Simpson CS, Boczek NJ, Tester DJ, Radbill AE, Mok NS, Hamilton RM, Kaufman ES, Eugenio PL, Weiss R, January C, McDaniel GM, Leather RA, Erickson C, Falik S, Behr ER, Wilde AAM, Sanatani S, Ackerman MJ, Van Petegem F, Krahn AD, Laksman Z. Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site. Europace. 2019 Aug pii: euz215. doi: 10.1093/europace/euz215. [Epub ahead of print] PubMed PMID: 31408100.

9. Kwan JZJ, Nguyen TF, Teves SS. Visualizing Transcription Factor Binding on Mitotic Chromosomes Using Single-Molecule Live-Cell Imaging. Methods Mol Biol. 2019; 2038:239-250. doi: 10.1007/978-1-4939-9674-2_16. PubMed PMID: 31407289.

Aug 12, Pubcrawler Hits:

1. Devine DV. Ironing out frequent blood donation. Lancet Haematol. 2019 Aug 2. pii: S2352-3026(19)30162-0. doi: 10.1016/S2352-3026(19)30162-0. [Epub ahead of print] PubMed PMID: 31383582.

2. Zhang AMY, Magrill J, de Winter TJJ, Hu X, Skovsø S, Schaeffer DF, Kopp JL, Johnson JD. Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development. Cell Metab. 2019 Jul 23. pii: S1550-4131(19)30376-6. doi: 10.1016/j.cmet.2019.07.003. [Epub ahead of print] PubMed PMID: 31378465.

3. Zelanis A, Oliveira AK, Prudova A, Huesgen PF, Tashima AK, Kizhakkedathu J, Overall CM, Serrano SMT. Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Substrates (TAILS) N-Terminomics. J Proteome Res. 2019 Aug 8. doi: 10.1021/acs.jproteome.9b00325. [Epub ahead of print] PubMed PMID: 31337208.

4. Tadini-Buoninsegni F, Mikkelsen SA, Mogensen LS, Molday RS, Andersen JP. Phosphatidylserine flipping by the P4-ATPase ATP8A2 is electrogenic. Proc Natl Acad Sci U S A. 2019 Aug 1. pii: 201910211. doi: 10.1073/pnas.1910211116. [Epub ahead of print] PubMed PMID: 31371510.

Aug 5, Pubcrawler Hits:

1. Carlson ML, Stacey RG, Young JW, Wason IS, Zhao Z, Rattray DG, Scott N, Kerr CH, Babu M, Foster LJ, Duong FVH. Profiling the E. coli membrane interactome captured in peptidisc libraries. Elife. 2019 Jul 31;8. pii: e46615. doi: 10.7554/eLife.46615. [Epub ahead of print] PubMed PMID: 31364989.

2. Heinkel F, Abraham L, Ko M, Chao J, Bach H, Hui LT, Li H, Zhu M, Ling YM, Rogalski JC, Scurll J, Bui JM, Mayor T, Gold MR, Chou KC, Av-Gay Y, McIntosh LP, Gsponer J. Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2019 Jul 31. pii: 201820683. doi:10.1073/pnas.1820683116. [Epub ahead of print] PubMed PMID: 31366629.

3. Tudurí E, Glavas MM, Asadi A, Baker RK, Ellis CE, Soukhatcheva G, Philit M, Huynh FK, Johnson JD, Bruce Verchere C, Kieffer TJ. AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells. Sci Rep. 2019 Jul 25;9(1):10829. doi: 10.1038/s41598-019-46735-2. PubMed PMID: 31346189; PubMed Central PMCID: PMC6658537.

4. Cembrowski MS. Single-cell transcriptomics as a framework and roadmap for understanding the brain. J Neurosci Methods. 2019 Jul 25;326:108353. doi: 10.1016/j.jneumeth.2019.108353. [Epub ahead of print] Review. PubMed PMID: 31351971.

Jul 29, Pubcrawler Hits:

1. Jobin PG, Solis N, Machado Y, Bell PA, Kwon NH, Kim S, Overall CM, Butler GS. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019 Jul 19. pii: jbc.RA119.009584. doi: 10.1074/jbc.RA119.009584. [Epub ahead of print] PubMed PMID: 31324718.

Jul 22, Pubcrawler Hits:

1. Musso PY, Junca P, Jelen M, Feldman-Kiss D, Zhang H, Chan RC, Gordon MD. Closed-loop optogenetic activation of peripheral or central neurons modulates feeding in freely moving Drosophila. Elife. 2019 Jul 19;8. pii: e45636. doi: 10.7554/eLife.45636. [Epub ahead of print] PubMed PMID: 31322499.

2. Hill L, Sumer-Bayraktar Z, Lewis JG, Morava E, Thaysen-Andersen M, Hammond GL. N-Glycosylation influences human corticosteroid-binding globulin measurements. Endocr Connect. 2019 Jul 1. pii: EC-19-0242.R1. doi: 10.1530/EC-19-0242. [Epub ahead of print] PubMed PMID: 31307013.

Jul 15, Pubcrawler Hits:

1. Andrault PM, Panwar P, Mackenzie NCW, Brömme D. Elastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification. Sci Rep. 2019 Jul 4;9(1):9682. doi: 0.1038/s41598-019-45918-1. PubMed PMID: 31273243; PubMed Central PMCID: PMC6609650.

2. Ozaki K, Thompson KJ, Simister RL, Crowe SA, Reinhard CT. Anoxygenic photosynthesis and the delayed oxygenation of Earth's atmosphere. Nat Commun. 2019 Jul 9;10(1):3026. doi: 10.1038/s41467-019-10872-z. PubMed PMID: 31289261; PubMed Central PMCID: PMC6616575.

3. Kuatsjah E, Verstraete MM, Kobylarz MJ, Liu AKN, Murphy MEP, Eltis LD. Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. J Biol Chem. 2019 Jul 10. pii: jbc.RA119.009428. doi: 10.1074/jbc.RA119.009428. [Epub ahead of print] PubMed PMID: 31292192.

4. Cait A, Cardenas E, Dimitriu P, Amenyogbe N, Dai D, Cait J, Sbihi H, Stiemsma L, Subbarao P, Mandhane PJ, Becker AB, Moraes TJ, Sears MR, Lefebvre DL, Azad MB, Kollmann T, Turvey SE, Mohn WW. Reduced genetic potential for butyrate fermentation in the gut microbiome of infants who develop allergic sensitization. J Allergy Clin Immunol. 2019 Jul 3. pii: S0091-6749(19)30891-7. doi: 10.1016/j.jaci.2019.06.029. [Epub ahead of print] PubMed PMID: 31279007.

5. Khater IM, Liu Q, Chou KC, Hamarneh G, Nabi IR. Super-resolution modularity analysis shows polyhedral caveolin-1 oligomers combine to form scaffolds and caveolae. Sci Rep. 2019 Jul 8;9(1):9888. doi: 10.1038/s41598-019-46174-z. PubMed PMID: 31285524.

6. Adams A, Yoo KM, Vogl W. Lipid transfer machinery is present at membrane contact sites associated with the internalization of junctions in Sertoli cells. Biol Reprod. 2019 Jul 11. pii: ioz120. doi: 10.1093/biolre/ioz120. [Epub ahead of print] PubMed PMID: 31292601.

Jul 8, Pubcrawler Hits:

1. Petrus P, Fernandez TL, Kwon MM, Huang JL, Lei V, Safikhan NS, Karunakaran S, O'Shannessy DJ, Zheng X, Catrina SB, Albone E, Laine J, Virtanen K, Clee SM, Kieffer TJ, Noll C, Carpentier AC, Johnson JD, Rydén M, Conway EM. Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation. EBioMedicine. 2019 Jun;44:489-501. doi: 10.1016/j.ebiom.2019.05.057. Epub 2019 Jun 17. PubMed PMID: 31221584.

2. Farr Zuend C, Nomellini JF, Smit J, Horwitz MS. A Caulobacter crescentus microbicide protects from vaginal infection with HIV-1(JR-CSF) in Humanized Bone Marrow-Liver-Thymus Mice. J Virol. 2019 Jun 26. pii: JVI.00614-19. doi: 10.1128/JVI.00614-19. [Epub ahead of print] PubMed PMID: 31243127.

Jul 1, Pubcrawler Hits:

1. Uribesalgo I, Hoffmann D, Zhang Y, Kavirayani A, Lazovic J, Berta J, Novatchkova M, Pai TP, Wimmer RA, László V, Schramek D, Karim R, Tortola L, Deswal S, Haas L, Zuber J, Szűcs M, Kuba K, Dome B, Cao Y, Haubner BJ, Penninger JM. Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy. EMBO Mol Med. 2019 Jun 24:e9266. doi: 10.15252/emmm.201809266. [Epub ahead of print] PubMed PMID: 31267692.

Jun 17, Pubcrawler Hits:

1. Shah BS, Shimell JJ, Bamji SX. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J Cell Sci. 2019 Jun 12. pii: jcs.230052. doi: 10.1242/jcs.230052. [Epub ahead of print] PubMed PMID: 31189538.

2. Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG. An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nat Microbiol. 2019 Jun 10. doi: 10.1038/s41564-019-0469-7. [Epub ahead of print] PubMed PMID: 31182795.

3. Bomkamp C, Padmanabhan N, Karimi B, Ge Y, Chao JT, Loewen CJR, Siddiqui TJ, Craig AM. Mechanisms of PTPσ-Mediated Presynaptic Differentiation. Front Synaptic Neurosci. 2019 May 22;11:17. doi: 10.3389/fnsyn.2019.00017. eCollection 2019. PubMed PMID: 31191292; PubMed Central PMCID: PMC6540616.

4. Verstraete MM, Morales LD, Kobylarz MJ, Loutet SA, Laakso HA, Pinter TB, Stillman MJ, Heinrichs DE, Murphy MEP. The heme-sensitive regulator SbnI has a bifunctional role in staphyloferrin B production by Staphylococcus aureus. J Biol Chem. 2019 Jun 13. pii: jbc.RA119.007757. doi: 10.1074/jbc.RA119.007757. [Epub ahead of print] PubMed PMID: 31197035.

5. Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GY. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proc Natl Acad Sci U S A. 2019 Jun 12. pii: 201900152. doi: 10.1073/pnas.1900152116. [Epub ahead of print] PubMed PMID: 31189595.

Jun 10, Pubcrawler Hits:

1. Bolger-Munro M, Choi K, Scurll JM, Abraham L, Chappell RS, Sheen D, Dang-Lawson M, Wu X, Priatel JJ, Coombs D, Hammer JA, Gold MR. Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and cell activation. Elife. 2019 Jun 3;8. pii: e44574. doi: 10.7554/eLife.44574. [Epub ahead of print] PubMed PMID: 31157616.

2. Armstrong Z, Liu F, Kheirandish S, Chen HM, Mewis K, Duo T, Morgan-Lang C, Hallam SJ, Withers SG. High-Throughput Recovery and Characterization of Metagenome-Derived Glycoside Hydrolase-Containing Clones as a Resource for Biocatalyst Development. mSystems. 2019 Jun 4;4(4). pii: e00082-19. doi: 10.1128/mSystems.00082-19. PubMed PMID: 31164449.

3. Spanier JA, Tse HM, Horwitz MS, Fife BT. Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes. Front Endocrinol (Lausanne). 2019 May 16;10:315. doi: 10.3389/fendo.2019.00315. eCollection 2019. PubMed PMID: 31156560; PubMed Central PMCID: PMC6532014.

4. Warsaba R, Sadasivan J, Jan E. Dicistrovirus-Host Molecular Interactions. Curr Issues Mol Biol. 2019 Jun 6;34:83-112. doi: 10.21775/cimb.034.083. [Epub ahead of print] PubMed PMID: 31167957.

5. Chopra S, Overall CM, Dufour A. Matrix metalloproteinases in the CNS: interferons get nervous. Cell Mol Life Sci. 2019 Jun 4. doi: 10.1007/s00018-019-03171-9. [Epub ahead of print] Review. PubMed PMID: 31165203.

6. Elling U, Woods M, Forment JV, Fu B, Yang F, Ng BL, Vicente JR, Adams DJ, Doe B, Jackson SP, Penninger JM, Balmus G. Derivation and maintenance of mouse haploid embryonic stem cells. Nat Protoc. 2019 Jun 3. doi: 10.1038/s41596-019-0169-z. [Epub ahead of print] PubMed PMID: 31160788.

Jun 03, Pubcrawler Hits:

1. Abbina S, Abbasi U, Gill A, Wong K, Kalathottukaren MT, Kizhakkedathu JN. Design of Safe Nanotherapeutics for the Excretion of Excess Systemic Toxic Iron. ACS Cent Sci. 2019 May 22;5(5):917-926. doi: 10.1021/acscentsci.9b00284. Epub 2019 Apr 11. PubMed PMID: 31139728; PubMed Central PMCID: PMC6535967.

2. Reina J, Zhou L, M Fontes MR, Panté N, Cella N. Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation. FEBS Open Bio. 2019 Mar 20. doi: 10.1002/2211-5463.12626. [Epub ahead of print] PubMed PMID: 31144423.

3. Rao S, Mondragón L, Pranjic B, Hanada T, Stoll G, Köcher T, Zhang P, Jais A, Lercher A, Bergthaler A, Schramek D, Haigh K, Sica V, Leduc M, Modjtahedi N, Pai TP, Onji M, Uribesalgo I, Hanada R, Kozieradzki I, Koglgruber R, Cronin SJ, She Z, Quehenberger F, Popper H, Kenner L, Haigh JJ, Kepp O, Rak M, Cai K, Kroemer G, Penninger JM. AIF-regulated oxidative phosphorylation supports lung cancer development. Cell Res. 2019 May 27. doi: 10.1038/s41422-019-0181-4. [Epub ahead of print] PubMed PMID: 31133695.

May 27, Pubcrawler Hits:

1. Louca S, Scranton MI, Taylor GT, Astor YM, Crowe SA, Doebeli M. Circumventing kinetics in biogeochemical modeling. Proc Natl Acad Sci U S A. 2019 May 16. pii: doi: 10.1073/pnas.1819883116. [Epub ahead of print] PubMed PMID:

2. Jyotsana N, Sharma A, Chaturvedi A, Budida R, Scherr M, Kuchenbauer F, Lindner R, Noyan F, Sühs KW, Stangel M, Grote-Koska D, Brand K, Vornlocher HP, Eder M, Thol F, Ganser A, Humphries RK, Ramsay E, Cullis P, Heuser M. Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. Ann Hematol. 2019 May 18. doi: 10.1007/s00277-019-03713-y. [Epub ahead of print] PubMed PMID: 31104089.

3. Senini V, Amara U, Paul M, Kim H. Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis. J Periodontol. 2019 May 20. doi: 10.1002/JPER.18-0596. [Epub ahead of print] PubMed PMID: 31106406.

4. Liu B, Feng S, Dairi G, Guan Q, Chafeeva I, Wang H, Liggins R, da Roza G, Kizhakkedathu JN, Du C. Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution. BMC Nephrol. 2019 May 21; 20(1) :181. doi: 10.1186/s12882-019-1376-0. PubMed PMID: 31113397.

5. Mothersole RG, MacDonald M, Kolesnikov M, Murphy MEP, Wolthers KR. Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin. Protein Sci. 2019 May 22. doi: 10.1002/pro.3661. [Epub ahead of print] PubMed PMID: 31116469.

6. Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M. The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. PLoS One. 2019 May 23;14(5):e0216423. doi: 10.1371/journal.pone.0216423. eCollection 2019. PubMed PMID: 31120902.

7. Rabea SM, Baradaran-Heravi A, Balgi AD, Krause A, Hosseini Farahabadi S, Roberge M, Grierson DS. 2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides. ACS Med Chem Lett. 2019 Apr 9;10(5):726-731. doi: 10.1021/ acsmedchemlett.8b00610. eCollection 2019 May 9. PubMed PMID: 31097990; PubMed Central PMCID: PMC6511968.

8. Raineki C, Morgan EJ, Ellis L, Weinberg J. Glucocorticoid receptor expression in the stress-limbic circuitry is differentially affected by prenatal alcohol exposure and adolescent stress. Brain Res. 2019 May 15. pii: S0006-8993(19)30274-4. doi: 10.1016/j.brainres.2019.05.019. [Epub ahead of print] PubMed PMID: 31102593.

May 20, Pubcrawler Hits:

1. Macdonald SS, Armstrong Z, Morgan-Lang C, Osowiecka M, Robinson K, Hallam SJ, Withers SG. Development and Application of a High-Throughput Functional Metagenomic Screen for Glycoside Phosphorylases. Cell Chem Biol. 2019 May 9. pii: S2451-9456(19)30113-8. doi: 10.1016/j.chembiol.2019.03.017. [Epub ahead of print] PubMed PMID: 31080075.

2. Lau GY, Barts N, Hartley RC, Tobler M, Richards JG, Murphy MP, Arndt S. Detection of changes in mitochondrial hydrogen sulfide in vivo in the fish model Poecilia mexicana (Poeciliidae). Biol Open. 2019 May 9;8(5). pii: bio041467. doi: 10.1242/bio.041467. PubMed PMID: 31072908.

3. Gardill BR, Rivera-Acevedo RE, Tung CC, Van Petegem F. Crystal structures of Ca(2+)-calmodulin bound to Na(V) C-terminal regions suggest role for EF-hand domain in binding and inactivation. Proc Natl Acad Sci U S A. 2019 May 9. pii: 201818618. doi: 10.1073/pnas.1818618116. [Epub ahead of print] PubMed PMID: 31072926.

4. Katsube M, Rolfe SM, Bortolussi SR, Yamaguchi Y, Richman JM, Yamada S, Vora SR. Analysis of facial skeletal asymmetry during foetal development using μCT imaging. Orthod Craniofac Res. 2019 May;22 Suppl 1:199-206. doi: 10.1111/ocr.12304. PubMed PMID: 31074127; PubMed Central PMCID: PMC6512839.

5. McSwiggen DT, Hansen AS, Teves SS, Marie-Nelly H, Hao Y, Heckert AB, Umemoto KK, Dugast-Darzacq C, Tjian R, Darzacq X. Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. Elife. 2019 May 7;8. pii: e47098. doi: 10.7554/eLife.47098. PubMed PMID: 31038454.

May 13, Pubcrawler Hits:

1. Frirdich E, Biboy J, Pryjma M, Lee J, Huynh S, Parker CT, Girardin SE, Vollmer W, Gaynor EC. The Campylobacter jejuni helical to coccoid transition involves changes to peptidoglycan and the ability to elicit an immune response. Mol Microbiol. 2019 May 9. doi: 10.1111/mmi.14269. [Epub ahead of print] PubMed PMID: 31070821.

2. Ehrhardt K, Steck N, Kappelhoff R, Stein S, Rieder F, Gordon IO, Boyle EC, Braubach P, Overall CM, Finlay BB, Grassl GA. Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis. Inflamm Bowel Dis. 2019 May 9. pii: izz070. doi: 10.1093/ibd/izz070. [Epub ahead of print] PubMed PMID: 31066456.

3. Haji-Ghassemi O, Yuchi Z, Van Petegem F. The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner. Mol Cell. Published: May 08, 2019DOI:

4. Tamura K, Foley MH, Gardill BR, Dejean G, Schnizlein M, Bahr CME, Louise Creagh A, van Petegem F, Koropatkin NM, Brumer H. Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cell Mol Life Sci. 2019 May 6. doi: 10.1007/s00018-019-03115-3. [Epub ahead of print] PubMed PMID: 31062073.

5. Caveney NA, Pavlin A, Caballero G, Bahun M, Hodnik V, de Castro L, Fornelos N, Butala M, Strynadka NCJ. Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure. 2019 Apr 10. pii: S0969-2126(19)30115-7. doi: 10.1016/j.str.2019.03.019. [Epub ahead of print] PubMed PMID: 31056420.

May 06, Pubcrawler Hits:

1. Gold MR, Reth MG. Antigen Receptor Function in the Context of the Nanoscale Organization of the B Cell Membrane. Annu Rev Immunol. 2019 Apr 26;37:97-123. doi: 10.1146/annurev-immunol-042718-041704. PubMed PMID: 31026412.

2. Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, Liu C, Walker CL, Jonasch E, Lefebvre L, Wu M, Lorincz MC, Li W, Li L, Xie W. SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development. Nat Genet. 2019 May;51(5):844-856. doi: 10.1038/s41588-019-0398-7. Epub 2019 Apr 29. PubMed PMID: 31040401.

3. Hendi A, Kurashina M, Mizumoto K. Intrinsic and extrinsic mechanisms of synapse formation and specificity in C. elegans. Cell Mol Life Sci. 2019 Apr 29. doi: 10.1007/s00018-019-03109-1. [Epub ahead of print] Review.

4. Gignac SJ, Hosseini-Farahabadi S, Akazawa T, Schuck NJ, Fu K, Richman JM. Robinow syndrome skeletal phenotypes caused by the WNT5AC83S variant are due to dominant interference with chondrogenesis. Hum Mol Genet. 2019 Apr 3. pii: ddz071. doi: 10.1093/hmg/ddz071. [Epub ahead of print] PubMed PMID: 31032853.

April 29, Pubcrawler Hits:

1. Conway EM. Polyphosphates and Complement Activation. Front Med (Lausanne). 2019 Apr 4;6:67. doi: 10.3389/fmed.2019.00067. eCollection 2019. Review. PubMed PMID: 31019911; PubMed Central PMCID: PMC6458250.

2. Kulkarni JA, Witzigmann D, Leung J, van der Meel R, Zaifman J, Darjuan MM, Grisch-Chan HM, Thöny B, Tam YYC, Cullis PR. Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads. Nanoscale. 2019 Apr 25. doi: 10.1039/c9nr02004g. [Epub ahead of print] PubMed PMID: 31021343.

3. Caveney NA, Caballero G, Voedts H, Niciforovic A, Worrall LJ, Vuckovic M, Fonvielle M, Hugonnet JE, Arthur M, Strynadka NCJ. Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun. 2019 Apr 23;10(1):1849. doi: 10.1038/s41467-019-09507-0. PubMed PMID: 31015395; PubMed Central PMCID: PMC6478713.

April 23, Pubcrawler Hits:

1. Kaner Z, Engelman R, Schuster R, Rider P, Greenberg D, Av-Gay Y, Benhar M, Lewis EC. S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination. Front Immunol. 2019 Apr 2;10:590. doi: 10.3389/fimmu.2019.00590. eCollection 2019. PubMed PMID: 31001247; PubMed Central PMCID: PMC6454134.

2. Geletu M, Taha Z, Arulanandam R, Mohan R, Assi HH, Castro MG, Nabi IR, Gunning PT, Raptis L PhD. Effect of Caveolin-1 upon Stat3-ptyr705 levels in breast and lung carcinoma cells. Biochem Cell Biol. 2019 Apr 15. doi: 10.1139/bcb-2018-0367. [Epub ahead of print] PubMed PMID: 30986357.

3. Trudel D, Avarvarei LM, Orain M, Turcotte S, Plante M, Grégoire J, Kappelhoff  R, Labbé DP, Bachvarov D, Têtu B, Overall CM, Bairati I. Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer. Pathol Res Pract. 2019 Mar 2. pii: S0344-0338(18)31674-1. doi: 10.1016/j.prp.2019.02.019. [Epub ahead of print] PubMed PMID: 30987833.

4. Paik YK, Overall CM, Corrales F, Deutsch EW, Lane L, Omenn GS. Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods. J Proteome Res. 2018 Dec 7;17(12):4023-4030. doi: 10.1021/acs.jproteome.8b00885. PubMed PMID: 30985145; PubMed Central PMCID: PMC6288998.

5. Fu L, Haage A, Kong N, Tanentzapf G, Li H. Dynamic protein hydrogels with reversibly tunable stiffness regulate human lung fibroblast spreading reversibly. Chem Commun (Camb). 2019 Apr 15. doi: 10.1039/c9cc01276a. [Epub ahead of print] PubMed PMID: 30984936.

April 15, Pubcrawler Hits:

1. Khadilkar RJ, Tanentzapf G. Septate junction components control Drosophila hematopoiesis through the Hippo pathway. Development. 2019 Apr 4;146(7). pii: dev166819. doi: 10.1242/dev.166819. PubMed PMID: 30890573.

April 8, Pubcrawler Hits:

1. Westhoff M, Eldstrom J, Murray CI, Thompson E, Fedida D. I (Ks) ion-channel pore conductance can result from individual voltage sensor movements. Proc Natl Acad Sci U S A. 2019 Mar 27. pii: 201811623. doi: 10.1073/pnas.1811623116. [Epub ahead of print] PubMed PMID: 30918124.

2. Au Yeung WK, Brind'Amour J, Hatano Y, Yamagata K, Feil R, Lorincz MC, Tachibana M, Shinkai Y, Sasaki H. Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection. Cell Rep. 2019 Apr 2;27(1):282-293.e4. doi: 10.1016/j.celrep.2019.03.002. PubMed PMID: 30943408.

3. Conroy BS, Grigg JC, Kolesnikov M, Morales LD, Murphy MEP. Staphylococcus aureus heme and siderophore-iron acquisition pathways. Biometals. 2019 Mar 25. doi: 10.1007/s10534-019-00188-2. [Epub ahead of print] PubMed PMID: 30911924.

4. Conroy BS, Grigg JC, Kolesnikov M, Morales LD, Murphy MEP. Staphylococcus aureus heme and siderophore-iron acquisition pathways. Biometals. 2019 Mar 25. doi: 10.1007/s10534-019-00188-2. [Epub ahead of print] PubMed PMID: 30911924.

5. Basson R, O'Loughlin JI, Weinberg J, Young AH, Bodnar T, Brotto LA. Dehydroepiandrosterone and cortisol as markers of HPA axis dysregulation in women with low sexual desire. Psychoneuroendocrinology. 2019 Mar 8;104:259-268. doi: 10.1016/j.psyneuen.2019.03.001. [Epub ahead of print] PubMed PMID: 30909007.

6. Buck J, Grossen P, Cullis PR, Huwyler J, Witzigmann D. Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery. ACS Nano. 2019 Apr 2. doi: 10.1021/acsnano.8b07858. [Epub ahead of print] PubMed PMID: 30908008.

March. 25, Pubcrawler Hits:

1. Ding H, Saer RG, Beatty JT. Porphyrin Excretion Resulting From Mutation of a Gene Encoding a Class I Fructose 1,6-Bisphosphate Aldolase in Rhodobacter capsulatus. Front Microbiol. 2019 Feb 22;10:301. doi: 10.3389/fmicb.2019.00301. eCollection 2019. PubMed PMID: 30853951; PubMed Central PMCID: PMC6395792.

2. Liou AY, Molday LL, Wang J, Andersen JP, Molday RS. Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. J Biol Chem. 2019 Mar 8. pii: jbc.RA118.007270. doi: 10.1074/jbc.RA118.007270. [Epub ahead of print] PubMed PMID: 30850395.

3. Freitas-Andrade M, Wang N, Bechberger JF, De Bock M, Lampe PD, Leybaert L, Naus CC. Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke. J Exp Med. 2019 Mar 14. pii: jem.20171452. doi: 10.1084/jem.20171452. [Epub ahead of print] PubMed PMID: 30872361.

4. Le Vasseur M, Chen VC, Huang K, Vogl WA, Naus CC. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers (Basel). 2019 Mar 11;11(3). pii: E343. doi: 10.3390/cancers11030343. PubMed PMID: 30862038.

5. Shafaattalab S, Li AY, Lin E, Stevens CM, Dewar LJ, Lynn FC, Sanatani S, Laksman Z, Morin RD, van Petegem F, Hove-Madsen L, Tieleman DP, Davis JP, Tibbits GF. In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants. Proc Natl Acad Sci U S A. 2019 Mar 18. pii: 201819023. doi: 10.1073/pnas.1819023116. [Epub ahead of print] PubMed PMID: 30886088.

6. Bowerman B, Sugioka K. Breaking Symmetry: Worm Cue Finally Found. Dev Cell. 2019 Mar 11;48(5):593-594. doi: 10.1016/j.devcel.2019.02.018. PubMed PMID: 30861371.

March. 11, Pubcrawler Hits:

1. Glavas MM, Hui Q, Tudurí E, Erener S, Kasteel NL, Johnson JD, Kieffer TJ. Early overnutrition reduces Pdx1 expression and induces β cell failure in Swiss Webster mice. Sci Rep. 2019 Mar 6; 9(1):3619. doi: 10.1038/s41598-019-39177-3. PubMed PMID: 30842440.

2. Latres E, Finan DA, Greenstein JL, Kowalski A, Kieffer TJ. Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy. Cell Metab. 2019 Mar 5; 29(3):545-563. doi: 10.1016/j.cmet.2019.02.007. Review. PubMed PMID: 30840911.

3. Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. Sci Rep. 2019 Mar 5; 9(1):3594. doi: 10.1038/s41598-019-40136-1. PubMed PMID: 30837605; PubMed Central PMCID: PMC6401103.

4. Pereira S, O'Dwyer SM, Webber TD, Baker RK, So V, Ellis CE, Yoon JS, Mojibian M, Glavas MM, Karunakaran S, Clee SM, Covey SD, Kieffer TJ. Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues. Sci Rep. 2019 Mar 1; 9(1):3307. doi: 10.1038/s41598-019-39498-3. PubMed PMID: 30824713; PubMed Central PMCID: PMC6397253.

5. Holman PJ, Baglot SL, Morgan E, Weinberg J. Effects of prenatal alcohol exposure on social competence: Asymmetry in play partner preference among heterogeneous triads of male and female rats. Dev Psychobiol. 2019 Mar 6. doi: 10.1002/dev.21842. [Epub ahead of print] PubMed PMID: 30843198.

7. Eid RS, Chaiton JA, Lieblich SE, Bodnar TS, Weinberg J, Galea LAM. Early and late effects of maternal experience on hippocampal neurogenesis, microglia, and the circulating cytokine milieu. Neurobiol Aging. 2019 Feb 2; 78:1-17. doi: 10.1016/j.neurobiolaging.2019.01.021. [Epub ahead of print] PubMed PMID: 30825663.

8. Borrel G, Adam PS, McKay LJ, Chen LX, Sierra-García IN, Sieber CMK, Letourneur Q, Ghozlane A, Andersen GL, Li WJ, Hallam SJ, Muyzer G, de Oliveira VM, Inskeep WP, Banfield JF, Gribaldo S. Wide diversity of methane and short-chain alkane metabolisms in uncultured archaea. Nat Microbiol. 2019 Mar 4. doi: 10.1038/s41564-019-0363-3. [Epub ahead of print] PubMed PMID: 30833729.

Feb. 25, Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Baldry SEL, Yang C, Tosefsky K, Balaton BP, Simpson EM, Brown CJ. How do genes that escape from X-chromosome inactivation contribute to Turner syndrome? Am J Med Genet C Semin Med Genet. 2019 Feb 19. doi: 10.1002/ajmg.c.31672. [Epub ahead of print] PubMed PMID: 30779428.

2. Cait J, Hughes MR, Zeglinski MR, Chan AW, Osterhof S, Scott RW, Canals Hernaez D, Cait A, Vogl AW, Bernatchez P, Underhill TM, Granville DJ, Murphy TH, Roskelley CD, McNagny KM. Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation. Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 201814766. doi: 10.1073/pnas.1814766116. [Epub ahead of print] PubMed PMID: 30787191.

Feb. 18, Pubcrawler Hits:

1. Haw J, Polzer J, Devine DV. Contextual factors influencing donor recruitment and cord blood collection: perspectives of frontline staff of the Canadian Blood Services' Cord Blood Bank. Transfusion. 2019 Feb 11. doi: 10.1111/trf.15185. [Epub ahead of print] PubMed PMID: 30741433.

2. Navas LE, Martínez FD, Taverna ME, Fetherolf MM, Eltis LD, Nicolau V, Estenoz D, Campos E, Benintende GB, Berretta MF. A thermostable laccase from Thermus sp. 2.9 and its potential for delignification of Eucalyptus biomass. AMB Express. 2019 Feb 12;9(1):24. doi: 10.1186/s13568-019-0748-y. PubMed PMID: 30756202.

3. Mikkelsen SA, Mogensen LS, Vilsen B, Molday RS, Vestergaard AL, Andersen JP. Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. J Biol Chem. 2019 Feb 13. pii: jbc.RA118.007240. doi: 10.1074/jbc.RA118.007240. [Epub ahead of print] PubMed PMID: 30760526.

4. Soni A, Lin C, Murphy M, Tanner ME. Peptides Containing meso-Oxa-Diaminopimelic Acid as Substrates for the Cell Shape-Determining Proteases Csd6 and Pgp2. Chembiochem. 2019 Feb 11. doi: 10.1002/cbic.201900011. [Epub ahead of print] PubMed PMID: 30746833.

5. Khater IM, Meng F, Nabi IR, Hamarneh G. Identification of Caveolin-1 Domain Signatures via Graphlet Analysis of Single Molecule Super-Resolution Data. Bioinformatics. 2019 Feb 13. doi: 10.1093/bioinformatics/btz113. [Epub ahead of print] PubMed PMID: 30759191.

6. Majewski DD, Worrall LJ, Hong C, Atkinson CE, Vuckovic M, Watanabe N, Yu Z, Strynadka NCJ. Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry. Nat Commun. 2019 Feb 7;10(1):626. doi: 10.1038/s41467-019-08477-7. PubMed PMID: 30733444; PubMed Central PMCID: PMC6367419.

7. Xu M, Singla J, Tocheva EI, Chang YW, Stevens RC, Jensen GJ, Alber F. De Novo Structural Pattern Mining in Cellular Electron Cryotomograms. Structure. 2019 Jan 31. pii: S0969-2126(19)30005-X. doi: 10.1016/j.str.2019.01.005. [Epub ahead of print] PubMed PMID: 30744995.

Feb. 11, Pubcrawler Hits:

1. Yang X, Kang N, Toyofuku WM, Scott MD. Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics. Immunobiology. 2018 Dec 28. pii: S0171-2985(18)30124-4. doi: 1016/j.imbio.2018.12.003. [Epub ahead of print] PubMed PMID: 30711357.

2. Maya-Martinez R, Alexander JAN, Otten CF, Ayala I, Vollmer D, Gray J, Bougault CM, Burt A, Laguri C, Fonvielle M, Arthur M, Strynadka NCJ, Vollmer W, Simorre JP. Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 From Staphylococcus aureus. Front Microbiol. 2019 Jan 18;9:3223. doi: 10.3389/fmicb.2018.03223. eCollection 2018. PubMed PMID: 30713527; PubMed Central PMCID: PMC6346638.

Feb. 04, Pubcrawler Hits:

1. Tamaru Y, Yoshida M, Eltis LD, Goodell B. Multiple iron reduction by methoxylated phenolic lignin structures and the generation of reactive oxygen species by lignocellulose surfaces. Int J Biol Macromol. 2019 Jan 27;128:340-346. doi: 10.1016/j.ijbiomac.2019.01.149. [Epub ahead of print] PubMed PMID: 30699335.

2. Quancard J, Klein T, Fung SY, Renatus M, Hughes N, Israël L, Priatel JJ, Kang S, Blank MA, Viner RI, Blank J, Schlapbach A, Erbel P, Kizhakkedathu J, Villard F, Hersperger R, Turvey SE, Eder J, Bornancin F, Overall CM. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Jan 28. doi: 10.1038/s41589-018-0222-1. [Epub ahead of print] PubMed PMID: 30692685.

3. Zeytuni N, Strynadka NCJ. A Hybrid Secretion System Facilitates Bacterial Sporulation: A Structural Perspective. Microbiol Spectr. 2019 Jan;7(1). doi: 10.1128/microbiolspec.PSIB-0013-2018. PubMed PMID: 30681070.

4. Arenaz-Callao MP, González Del Río R, Lucía Quintana A, Thompson CJ, Mendoza-Losana A, Ramón-García S. Triple oral beta-lactam containing therapy for  Buruli ulcer treatment shortening. PLoS Negl Trop Dis. 2019 Jan 28; 13(1):e0007126. doi: 10.1371/journal.pntd.0007126. [Epub ahead of print] PubMed PMID: 30689630.

Jan. 21, Pubcrawler Hits:

1. Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ. Author Correction: A compendium of geochemical information from the Saanich Inlet water column. Sci Data. 2019 Jan 15; 6(1):1. doi: 10.1038/s41597-018-0005-2. PubMed PMID: 30647409; PubMed Central PMCID: PMC6333813.

2. Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, Lindenhofer D, Chen G, Boehm M, Agu CA, Yang F, Fu B, Zuber J, Knoblich JA, Kerjaschki D, Penninger JM. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019 Jan 16. doi: 10.1038/s41586-018-0858-8. [Epub ahead of print] PubMed PMID: 30651639.

Jan. 14, Pubcrawler Hits:

1. Law S, Du X, Panwar P, Honson NS, Pfeifer T, Roberge M, Brömme D.Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening. Biochem J. 2019 Jan 8. pii: BCJ20180851. doi: 10.1042/BCJ20180851. [Epub ahead of print] PubMed PMID: 30622151.

2. Spitalnik SL, Devine DV. Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains. Transfusion. 2019 Jan;59(1):2-5. doi: 10.1111/trf.15066. PubMed PMID: 30615814.

3. Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2018 Dec 21. pii: S0092-8674(18)31560-5. doi: 10.1016/j.cell.2018.11.035. [Epub ahead of print] PubMed PMID: 30612739.

4. Lo BC, Shin SB, Canals Hernaez D, Refaeli I, Yu HB, Goebeler V, Cait A, Mohn WW, Vallance BA, McNagny KM. IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic Salmonella Infection. J Immunol. 2019 Jan 7. pii: ji1801308. doi: 10.4049/jimmunol.1801308. [Epub ahead of print] PubMed PMID: 30617224.

5. Yang H, Li Y, Zhao M, Wu F, Wang X, Xiao W, Wang Y, Zhang J, Wang F, Xu F, Zeng WF, Overall CM, He SM, Chi H, Xu P. Precision de novo peptide sequencing using mirror proteases of Ac-LysargiNase and trypsin for large-scale proteomics. Mol Cell Proteomics. 2019 Jan 8. pii: mcp.TIR118.000918. doi: 10.1074/mcp.TIR118.000918. [Epub ahead of print] PubMed PMID: 30622160.

6. Ng MY, Zhang H, Weil A, Singh V, Jamiolkowski R, Baradaran-Heravi A, Roberge M, Jacobson A, Friesen W, Welch E, Goldman YE, Cooperman BS. New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. ACS Med Chem Lett. 2018 Nov 21;9(12):1285-1291. doi: 10.1021/acsmedchemlett.8b00472. eCollection 2018 Dec 13. PubMed PMID: 30613341; PubMed Central PMCID: PMC6295867.

Jan. 07, Pubcrawler Hits:

1. Sturm A, Fowle DA, Jones C, Leslie K, Nomosatryo S, Henny C, Canfield DE, Crowe SA. Rates and pathways of CH(4) oxidation in ferruginous Lake Matano, Indonesia. Geobiology. 2018 Dec 28. doi: 10.1111/gbi.12325. [Epub ahead of print] PubMed PMID: 30593722.

2. Young J, Duong F. Investigating the stability of the SecA-SecYEG complex during protein translocation across the bacterial membrane. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006447. doi: 10.1074/jbc.RA118.006447. [Epub ahead of print] PubMed PMID: 30602566.

3. Perez-Borrajero C, Lin CS, Okon M, Scheu K, Graves BJ, Murphy MEP, McIntosh LP. The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J Mol Biol. 2018 Dec 28. pii: S0022-2836(18)31286-5. doi: 10.1016/j.jmb.2018.12.011. [Epub ahead of print] PubMed PMID: 30597162.

4. Zimmermann P, Messina N, Mohn WW, Finlay BB, Curtis N. Association between the intestinal microbiota and allergic sensitization, eczema, and asthma: A systematic review. J Allergy Clin Immunol. 2018 Dec 29. pii: S0091-6749(18)31431-3. doi: 10.1016/j.jaci.2018.09.025. [Epub ahead of print] PubMed PMID: 30600099.

5. Richman JM. Shedding new light on the mysteries of tooth eruption. Proc Natl Acad Sci U S A. 2019 Jan 2. pii: 201819412. doi: 10.1073/pnas.1819412116. [Epub ahead of print] PubMed PMID: 30602459.


Dec. 31, Pubcrawler Hits:

1. Kajiwara Y, Wang E, Wang M, Sin WC, Brennand KJ, Schadt E, Naus CC, Buxbaum J, Zhang B. GJA1 (connexin43) is a key regulator of Alzheimer's disease pathogenesis. Acta Neuropathol Commun. 2018 Dec 21;6(1):144. doi: 10.1186/s40478-018-0642-x. PubMed PMID: 30577786.

2. Johnson SB, Emmons EB, Lingg RT, Anderson RM, Romig-Martin SA, LaLumiere RT, Narayanan NS, Viau V, Radley JJ. Prefrontal-bed nucleus circuit modulation of a passive coping response set. J Neurosci. 2018 Dec 20. pii: 1421-18. doi: 10.1523/JNEUROSCI.1421-18.2018. [Epub ahead of print] PubMed PMID: 30573644.

Dec. 24, Pubcrawler Hits:

1. Johnson P, Arif AA, Lee-Sayer SSM, Dong Y. Hyaluronan and Its Interactions With Immune Cells in the Healthy and Inflamed Lung. Front Immunol. 2018 Nov 29; 9:2787. doi: 10.3389/fimmu.2018.02787. eCollection 2018. Review. PubMed PMID: 30555472; PubMed Central PMCID: PMC6281886.

2. Modi H, Johnson JD. Folding mutations suppress early beta-cell proliferation. Elife. 2018 Dec 14; 7. pii: e43475. doi: 10.7554/eLife.43475. PubMed PMID: 30547883; PubMed Central PMCID: PMC6294546.

3. Liu KYP, Lu XJD, Zhu YS, Le N, Kim H, Poh CF. Plasma-Derived Inflammatory Proteins Predict Oral Squamous Cell Carcinoma. Front Oncol. 2018 Dec 4; 8:585. doi: 10.3389/fonc.2018.00585. eCollection 2018. PubMed PMID: 30564558; PubMed Central PMCID: PMC6288174.

4. Chohan H, Esfandiarei M, Arman D, Van Raamsdonk CD, van Breemen C, Friedman JM, Jett KA. Neurofibromin haploinsufficiency results in altered spermatogenesis in a mouse model of neurofibromatosis type 1. PLoS One. 2018 Dec 20; 13(12):e0208835. doi: 10.1371/journal.pone.0208835. eCollection 2018. PubMed PMID: 30571760.

5. Lussier AA, Bodnar TS, Mingay M, Morin AM, Hirst M, Kobor MS, Weinberg J. Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues. Front Genet. 2018 Dec 4;9:610. doi: 10.3389/fgene.2018.00610. eCollection 2018. PubMed PMID: 30568673; PubMed Central PMCID: PMC6290329.

Dec. 17, Pubcrawler Hits:

1. Ng KW, Marshall EA, Enfield KS, Martin SD, Milne K, Pewarchuk ME, Abraham N, Lam WL. Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma. Oncoimmunology. 2018 Sep 6;7(12):e1504728. doi: 10.1080/2162402X.2018.1504728. eCollection 2018. PubMed PMID: 30524903; PubMed Central PMCID: PMC6279324.

2. Levy-Booth DJ, Giesbrecht IJW, Kellogg CTE, Heger TJ, D'Amore DV, Keeling PJ, Hallam SJ, Mohn WW. Seasonal and ecohydrological regulation of active microbial populations involved in DOC, CO(2), and CH(4) fluxes in temperate rainforest soil. ISME J. 2018 Dec 11. doi: 10.1038/s41396-018-0334-3. [Epub ahead of print] PubMed PMID: 30538276.

3. Späth MR, Bartram MP, Palacio-Escat N, Hoyer KJR, Debes C, Demir F, Schroeter CB, Mandel AM, Grundmann F, Ciarimboli G, Beyer A, Kizhakkedathu JN, Brodesser S, Göbel H, Becker JU, Benzing T, Schermer B, Höhne M, Burst V, Saez-Rodriguez J, Huesgen PF, Müller RU, Rinschen MM. The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Kidney Int. 2018 Nov 29. pii: S0085-2538(18)30644-6. doi: 10.1016/j.kint.2018.08.037. [Epub ahead of print] PubMed PMID: 30522767.

4. Brockerman JA, Okon M, Withers SG, McIntosh LP. The pK(a) values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme. Protein Sci. 2018 Dec 7. doi: 10.1002/pro.3562. [Epub ahead of print] PubMed PMID: 30537432.

5. Ipsiroglu OS, Wind K, Hung YA, Berger M, Chan F, Yu W, Stockler S, Weinberg J. Prenatal alcohol exposure and sleep-wake behaviors: exploratory and naturalistic observations in the clinical setting and in an animal model. Sleep Med. 2018 Oct 25;54:101-112. doi: 10.1016/j.sleep.2018.10.006. [Epub ahead of print] PubMed PMID: 30530254.

Dec. 10, Pubcrawler Hits:

1. Pawluski JL, Brain U, Hammond GL, Oberlander TF. Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression. Arch Womens Ment Health. 2018 Dec 1. doi: 10.1007/s00737-018-0931-1. [Epub ahead of print] PubMed PMID: 30506371.

Dec. 03, Pubcrawler Hits:

1. Vuilleumier R, Lian T, Flibotte S, Khan ZN, Fuchs A, Pyrowolakis G, Allan DW. Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element. Nucleic Acids Res. 2018 Nov 22. doi: 10.1093/nar/gky1135. [Epub ahead of print] PubMed PMID: 30476189.

2. Kerr CH, Dalwadi U, Scott NE, Yip CK, Foster LJ, Jan E. Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells. Sci Rep. 2018 Nov 26;8(1):17353. doi: 10.1038/s41598-018-35717-5. PubMed PMID: 30478341.

3. Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G. Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo. Cell Rep. 2018 Nov 27;25(9):2401-2416.e5. doi: 10.1016/j.celrep.2018.10.098. PubMed PMID: 30485809.

Nov. 26, Pubcrawler Hits:

1. González A, Fernandino JI, Elisio M, Chalde T, Miranda LA, Hammond GL, Somoza GM. Sex Hormone Binding Globuling during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis). Gen Comp Endocrinol. 2018 Nov 19. pii: S0016-6480(18)30365-4. doi: 10.1016/j.ygcen.2018.11.010. [Epub ahead of print] PubMed PMID: 30465767.

2. Tunster SJ, Van de Pette M, Creeth HDJ, Lefebvre L, John RM. Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome. Dis Model
Mech. 2018 Nov 16;11(11). pii: dmm035832. doi: 10.1242/dmm.035832. PubMed PMID: 30158284; PubMed Central PMCID: PMC6262809.

3. Hill LA, Vassiliadi DA, Dimopoulou I, Anderson AJ, Boyle LD, Kilgour AHM, Stimson RH, Machado Y, Overall CM, Walker BR, Lewis JG, Hammond GL. Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma. J Endocrinol. 2019 Jan 1; 240(1):27-39. doi: 10.1530/JOE-18-0479. PubMed PMID: 30452386.

4. Kan B, Michalski C, Fu H, Au HHT, Lee K, Marchant EA, Cheng MF, Anderson-Baucum E, Aharoni-Simon M, Tilley P, Mirmira RG, Ross CJ, Luciani DS, Jan E, Lavoie PM. Cellular metabolism constrains innate immune responses in early human ontogeny. Nat Commun. 2018 Nov 16; 9(1):4822. doi: 10.1038/s41467-018-07215-9. PubMed PMID: 30446641; PubMed Central PMCID: PMC6240060.

5. Shimazu-Kuwahara S, Kanemaru Y, Harada N, Ikeguchi E, Ueda Y, Yamane S, Murata Y, Yasoda A, Kieffer TJ, Inagaki N. Glucose-dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance but deteriorated bone loss in ovariectomized mice. J Diabetes Investig. 2018 Nov 19. doi:10.1111/jdi.12978. [Epub ahead of print] PubMed PMID: 30451382.

6.Werth AJ, Lillie MA, Piscitelli MA, Vogl AW, Shadwick RE. Slick, stretchy fascia underlies the sliding tongue of rorquals. Anat Rec (Hoboken). 2018 Nov 17.doi: 10.1002/ar.24035. [Epub ahead of print] PubMed PMID: 30447133.

7. Fujiwara S, Hoshizaki M, Ichida Y, Lex D, Kuroda E, Ishii KJ, Magi S, Okada M, Takao H, Gandou M, Imai H, Hara R, Herzog H, Yoshimura A, Okamura H, Penninger JM, Slutsky AS, Uhlig S, Kuba K, Imai Y. Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection. Nat Microbiol. 2018 Nov 19. doi: 10.1038/s41564-018-0289-1. [Epub ahead of print] PubMed PMID: 30455472.

Nov. 12, Pubcrawler Hits:

1. Kerr CH, Wang QS, Moon KM, Keatings K, Allan DW, Foster LJ, Jan E. IRES-dependent ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral infection. Nucleic Acids Res. 2018 Nov 10. doi: 10.1093/nar/gky1121. [Epub ahead of print] PubMed PMID: 30418631.

2. Roston TM, Haji-Ghassemi O, LaPage MJ, Batra AS, Bar-Cohen Y, Anderson C, Lau YR, Maginot K, Gebauer RA, Etheridge SP, Potts JE, Van Petegem F, Sanatani S. Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry. PLoS One. 2018 Nov 7; 13(11):e0205925. doi: 10.1371/journal.pone.0205925. eCollection 2018. PubMed PMID: 30403697; PubMed Central PMCID: PMC6221297.

Nov. 05, Pubcrawler Hits:

1. Marshall NC, Klein T, Thejoe M, von Krosigk N, Kizhakkedathu J, Finlay BB, Overall CM. Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation. J Proteome Res. 2018 Oct 29. doi: 10.1021/acs.jproteome.8b00675. [Epub ahead of print] PubMed PMID: 30371095.

2. Mei Y, Yu K, Lo JCY, Takeuchi LE, Hadjesfandiari N, Yazdani-Ahmadabadi H, Brooks DE, Lange D, Kizhakkedathu JN. Polymer-Nanoparticle Interaction as a Design Principle in the Development of a Durable Ultrathin Universal Binary Antibiofilm Coating with Long-Term Activity. ACS Nano. 2018 Oct 29. doi: 10.1021/acsnano.8b05512. [Epub ahead of print] PubMed PMID: 30354054.

3. McDiarmid TA, Au V, Loewen AD, Liang J, Mizumoto K, Moerman DG, Rankin CH. CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance. Dis Model Mech. 2018 Oct 25. pii: dmm.036517. doi: 10.1242/dmm.036517. [Epub ahead of print] PubMed PMID: 30361258.

4. Tham DKL, Moukhles H. Towards a better understanding of AQP4's role in astrocytic process extension: An Editorial for 'Involvement of aquaporin-4 in laminin-enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and a-syntrophin in aquaporin-4 expression' on doi:10.1111/jnc.14548. J Neurochem. 2018 Oct 30. doi: 10.1111/jnc.14590. [Epub ahead of print] PubMed PMID: 30378126.

5. Redfield RJ, Soucy SM. Evolution of Bacterial Gene Transfer Agents. Front Microbiol. 2018 Oct 25; 9:2527. doi: 10.3389/fmicb.2018.02527. eCollection 2018. PubMed PMID: 30410473; PubMed Central PMCID: PMC6209664.

6. Alexander JAN, Chatterjee SS, Hamilton SM, Eltis LD, Chambers HF, Strynadka NCJ. Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. J Biol Chem. 2018 Oct 26. pii: jbc.RA118.004952. doi: 10.1074/jbc.RA118.004952. [Epub ahead of print] PubMed PMID: 30366985.

7. Lam VYY, Raineki C, Wang LY, Chiu M, Lee G, Ellis L, Yu W, Weinberg J. Role of corticosterone in anxiety- and depressive-like behavior and HPA regulation following prenatal alcohol exposure. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Oct 24; 90:1-15. doi: 10.1016/j.pnpbp.2018.10.008. [Epub ahead of print]PubMed PMID: 30367959.

Oct. 29, Pubcrawler Hits:

1. Lemieux MJ, Denault JB, Overall CM. Highlight: Frontiers in Proteolysis. Biol Chem. 2018 Oct 26. pii: /j/bchm.ahead-of-print/hsz-2018-0401/hsz-2018-0401.xml. doi: 10.1515/hsz-2018-0401. [Epub ahead of print] PubMed PMID: 30352023.

2. Wang K, Holt C, Lu J, Brohus M, Larsen KT, Overgaard MT, Wimmer R, Van Petegem F. Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc Natl Acad Sci US A. 2018 Oct 22. pii: 201808733. doi: 10.1073/pnas.1808733115. [Epub ahead of print] PubMed PMID: 30348784.

Oct. 22, Pubcrawler Hits:

1. Thompson E, Eldstrom J, Westhoff M, McAfee D, Fedida D. The I(Ks) Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry. Biophys J. 2018 Sep 27. pii: S0006-3495(18)31072-5. doi: 10.1016/j.bpj.2018.09.018. [Epub ahead of print] PubMed PMID: 30314657.

2. Molday LL, Cheng CL, Molday RS. Cell-Specific Markers for the Identification of Retinal Cells and Subcellular Organelles by Immunofluorescence Microscopy. Methods Mol Biol. 2019;1834:293-310. doi: 10.1007/978-1-4939-8669-9_19. PubMed PMID: 30324451.

3. Adams A, Sriram A, Vogl AW. Internalization of intact intercellular junctions in the testis by clathrin/actin-mediated endocytic structures: Tubulobulbar complexes. Anat Rec (Hoboken). 2018 Oct 12. doi: 10.1002/ar.23963. [Epub ahead of print] PubMed PMID: 30312540.

4. Moukarzel S, Dyer RA, Garcia C, Wiedeman AM, Boyce G, Weinberg J, Keller BO, Elango R, Innis SM. Milk Fat Globule Membrane Supplementation in Formula-fed Rat Pups Improves Reflex Development and May Alter Brain Lipid Composition. Sci Rep. 2018 Oct 15;8(1):15277. doi: 10.1038/s41598-018-33603-8. PubMed PMID: 30323309.

Oct. 15, Pubcrawler Hits:

1. Jaeger AH, Stanley M, Weiss ZF, Musso PY, Chan RC, Zhang H, Feldman-Kiss D, Gordon MD. A complex peripheral code for salt taste in Drosophila. Elife. 2018 Oct 11;7. pii: e37167. doi: 10.7554/eLife.37167. PubMed PMID: 30307393.

2. Nayak A, Kim DY, Trnka MJ, Kerr CH, Lidsky PV, Stanley DJ, Rivera BM, Li KH, Burlingame AL, Jan E, Frydman J, Gross JD, Andino R. A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability. Cell Host Microbe. 2018 Oct 10;24(4):542-557.e9. doi: 10.1016/j.chom.2018.09.006. PubMed PMID: 30308158.

3. Myette-Côté É, Durrer C, Neudorf H, Bammert TD, Botezelli JD, Johnson JD, DeSouza CA, Little JP. Short-term low-carbohydrate high-fat diet with or without post-meal walks on glycemic control and inflammation in type 2 diabetes: A randomized trial. Am J Physiol Regul Integr Comp Physiol. 2018 Oct 10. doi: 10.1152/ajpregu.00240.2018. [Epub ahead of print] PubMed PMID: 30303707.

4. Neumann UH, Kwon MM, Baker RK, Kieffer TJ. Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice. Am J Physiol Endocrinol Metab. 2018 Oct 9. doi: 10.1152/ajpendo.00159.2018. [Epub ahead of print] PubMed PMID: 30300012.

Oct. 08, Pubcrawler Hits:

1. Mallia-Milanes B, Dufour A, Philp C, Solis N, Klein T, Fischer M, Bolton CE, Shapiro SD, Overall CM, Johnson SR. TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 4. doi: 10.1152/ajplung.00175.2018. [Epub ahead of print] PubMed PMID: 30284925.

2. Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H. Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate. Commun Biol. 2018 Aug 17;1:120. doi: 10.1038/s42003-018-0121-8. eCollection 2018. PubMed PMID: 30272000.

3. Adam N, Trumm M, Smith VC, MacGillivray RTA, Panak PJ. Incorporation of transuranium elements: coordination of Cm(iii) to human serum transferrin. Dalton Trans. 2018 Oct 1. doi: 10.1039/c8dt02915f. [Epub ahead of print]. PubMed PMID: 30270390.

Oct. 01, Pubcrawler Hits:

1. Wilhelm RC, Singh R, Eltis LD, Mohn WW. Bacterial contributions to delignification and lignocellulose degradation in forest soils with metagenomic and quantitative stable isotope probing. ISME J. 2018 Sep 26. doi: 10.1038/s41396-018-0279-6. [Epub ahead of print] PubMed PMID: 30258172.

Sep. 24, Pubcrawler Hits:

1. Boraschi-Diaz I, Mort JS, Brömme D, Senis YA, Mazharian A, Komarova SV. Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation. Bone. 2018 Sep 12;117:23-30. doi: 10.1016/j.bone.2018.09.006. [Epub ahead of print] PubMed PMID:30217615.

2. Kenward PA, Simister RL, Morgan-Lang C, Finke N, Sturm A, Hallam SJ, Crowe SA. Recovering cellular biomass from fluids using chemical flocculation. Environ Microbiol Rep. 2018 Sep 19. doi: 10.1111/1758-2229.12690. [Epub ahead of print]PubMed PMID: 30230256.

3. Leach Bennett J, Devine DV. Risk-based decision making in transfusion medicine. Vox Sang. 2018 Sep 19. doi: 10.1111/vox.12708. [Epub ahead of print] Review. PubMed PMID: 30232803.

4. Martin BJE, Chruscicki AT, Howe LJ. Transcription Promotes the Interaction of the FAcilitates Chromatin Transactions (FACT) Complex with Nucleosomes in Saccharomyces cerevisiae. Genetics. 2018 Sep 20. pii: genetics.301349.2018. doi:  10.1534/genetics.118.301349. [Epub ahead of print] PubMed PMID: 30237209.

Sep. 17, Pubcrawler Hits:

1. Pirapaharan DC, Søe K, Panwar P, Madsen JS, Bergmann ML, Overgaard M, Brömme D, Delaisse JM. A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture. Calcif Tissue Int. 2018 Sep 7. doi: 10.1007/s00223-018-0472-7. [Epub ahead of print] PubMed PMID: 30194476.

2. Pancaroglu R, Van Petegem F. Calcium Channelopathies: Structural Insights into Disorders of the Muscle Excitation-Contraction Complex. Annu Rev Genet. 2018 Sep 12. doi: 10.1146/annurev-genet-120417-031311. [Epub ahead of print] PubMed PMID: 30208288.

Sep. 10, Pubcrawler Hits:

1. von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA. Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial. Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28. PubMed PMID: 30177038.

2. Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E. Screening of red blood cells for extracellular vesicle content as a product quality indicator. Transfusion. 2018 Aug 31. doi: 10.1111/trf.14782. [Epub ahead of print] PubMed PMID: 30168148.

Sep. 3, Pubcrawler Hits:

1. Dalal K, Ban F, Li H, Morin H, Roshan-Moniri M, Tam KJ, Shepherd A, Sharma A, Peacock J, Carlson ML, LeBlanc E, Perez C, Duong F, Ong CJ, Rennie PS, Cherkasov A. Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer. Cancer Lett. 2018 Aug 27; 437:35-43. doi: 10.1016/j.canlet.2018.08.016. [Epub ahead of print] PubMed PMID: 30165195.

Aug 27, Pubcrawler Hits:

1. Lei CL, Kellard JA, Hara M, Johnson JD, Rodriguez B, Briant LJB. Beta-cell hubs maintain Ca(2+) oscillations in human and mouse islet simulations. Islets. 2018;10(4):151-167. doi: 10.1080/19382014.2018.1493316. PubMed PMID: 30142036.

2. Kalathottukaren MT, Creagh AL, Abbina S, Lu G, Karbarz MJ, Pandey A, Conley PB, Kizhakkedathu JN, Haynes C. Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors. Blood Adv. 2018 Aug 28;2(16):2104-2114. doi: 10.1182/bloodadvances.2016003616. PubMed PMID: 30135185.

3. Meneksedag-Erol D, Kizhakkedathu JN, Tang T, Uludağ H. Molecular Dynamics Simulations on Nucleic Acid Binding Polymers Designed To Arrest Thrombosis. ACS Appl Mater Interfaces. 2018 Aug 20. doi: 10.1021/acsami.8b09914. [Epub ahead of print] PubMed PMID: 30085650.

4. Brind'Amour J, Kobayashi H, Richard Albert J, Shirane K, Sakashita A, Kamio A, Bogutz A, Koike T, Karimi MM, Lefebvre L, Kono T, Lorincz MC. LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation. Nat Commun. 2018 Aug 20;9(1):3331. doi: 10.1038/s41467-018-05841-x. PubMed PMID: 30127397; PubMed Central PMCID: PMC6102241.

5. Omenn GS, Lane L, Overall CM, Corrales FJ, Schwenk JM, Paik YK, Van Eyk JE, Liu S, Snyder M, Baker MS, Deutsch EW. Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project. J Proteome Res. 2018 Aug 23. doi: 10.1021/acs.jproteome.8b00441. [Epub ahead of print] PubMed PMID: 30099871.

6. Blaukopf M, Worrall L, Kosma P, Strynadka NCJ, Withers SG. Insights into Heptosyltransferase I Catalysis and Inhibition through the Structure of Its Ternary Complex. Structure. 2018 Jul 23. pii: S0969-2126(18)30247-8. doi: 10.1016/j.str.2018.07.001. [Epub ahead of print] PubMed PMID: 30122450.

Aug 20, Pubcrawler Hits:

1. Carlson ML, Young JW, Zhao Z, Fabre L, Jun D, Li J, Li J, Dhupar HS, Wason I, Mills AT, Beatty JT, Klassen JS, Rouiller I, Duong F. The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution. Elife. 2018  Aug 15;7. pii: e34085. doi: 10.7554/eLife.34085. PubMed PMID: 30109849; PubMed Central PMCID: PMC6093710.

2. Bogutz AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, Gu T, Gertsenstein M, Nagy A, Lefebvre L. Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. PLoS Genet. 2018 Aug 10;14(8):e1007587. doi: 10.1371/journal.pgen.1007587. [Epub ahead of print] PubMed PMID: 30096149.

3. Bergeron JRC, Brockerman JA, Vuckovic M, Deng W, Okon M, Finlay BB, McIntosh LP, Strynadka NCJ. Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. Protein Sci. 2018 Aug 10. doi: 10.1002/pro.3447.[Epub ahead of print] PubMed PMID: 30095200.

4. Holman PJ, Ellis L, Morgan E, Weinberg J. Prenatal alcohol exposure disrupts male adolescent social behavior and oxytocin receptor binding in rodents. Horm Behav. 2018 Aug 16;105:115-127. doi: 10.1016/j.yhbeh.2018.08.004. [Epub ahead of print] PubMed PMID: 30110605.

5. Nassar R, Wong E, Bui JM, Yip CK, Li H, Gsponer J, Lamour G. Mechanical Anisotropy in GNNQQNY Amyloid Crystals. J Phys Chem Lett. 2018 Aug 15:4901-4909. doi: 10.1021/acs.jpclett.8b02027. [Epub ahead of print] PubMed PMID: 30102541.

Aug 13, Pubcrawler Hits:

1. Zatmári D, Xue B, Kannan B, Burtnick LD, Bugyi B, Nyitrai M, Robinson RC. ATP competes with PIP2 for binding to gelsolin. PLoS One. 2018 Aug 7;13(8):e0201826. doi: 10.1371/journal.pone.0201826. eCollection 2018. PubMed PMID: 30086165.

2. Liu MM, Boinett CJ, Chan ACK, Parkhill J, Murphy MEP, Gaynor EC. Investigating the Campylobacter jejuni Transcriptional Response to Host Intestinal Extracts Reveals the Involvement of a Widely Conserved Iron Uptake System. MBio. 2018 Aug 7; 9(4). pii: e01347-18. doi: 10.1128/mBio.01347-18. PubMed PMID: 30087169.

3. Wang C, Fung G, Deng H, Jagdeo J, Mohamud Y, Xue YC, Jan E, Hirota JA, Luo H. NLRP3 deficiency exacerbates enterovirus infection in mice. FASEB J. 2018 Aug 6:fj201800301RRR. doi: 10.1096/fj.201800301RRR. [Epub ahead of print] PubMed PMID: 30080445.

4. Fukuda Y, Matsusaki T, Tse KM, Mizohata E, Murphy MEP, Inoue T. Crystallographic study of dioxygen chemistry in a copper-containing nitrite reductase from Geobacillus thermodenitrificans. Acta Crystallogr D Struct Biol. 2018 Aug 1;74(Pt 8):769-777. doi: 10.1107/S2059798318010082. Epub 2018 Jul 24. PubMed PMID: 30082512.

Aug 06, Pubcrawler Hits:

1. Chen X, Shibata AC, Hendi A, Kurashina M, Fortes E, Weilinger NL, MacVicar BA, Murakoshi H, Mizumoto K. Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans. Elife. 2018 Jul 31;7. pii: e38801. doi: 10.7554/eLife.38801. PubMed PMID: 30063210.

2. Pryzdial ELG, Lee FMH, Lin BH, Carter RLR, Tegegn TZ, Belletrutti MJ. Blood coagulation dissected. Transfus Apher Sci. 2018 Jul 20. pii: S1473-0502(18)30281-7. doi: 10.1016/j.transci.2018.07.003. [Epub ahead of print] Review. PubMed PMID: 30049564.

3. Neuenschwander R, Hookenson K, Brain U, Grunau RE, Devlin AM, Weinberg J, Diamond A, Oberlander TF. Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls. Dev Psychopathol. 2018 Aug;30(3):953-969. doi: 10.1017/S095457941800041X. PubMed PMID: 30068413.

Jul 30, Pubcrawler Hits:

1. Chen S, Zaifman J, Kulkarni JA, Zhigaltsev IV, Tam YK, Ciufolini MA, Tam YYC, Cullis PR. Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids. J Control Release.2018 Jul 17;286:46-54. doi: 10.1016/j.jconrel.2018.07.026. [Epub ahead of print] PubMed PMID: 30026080.

2. Thompson E, Eldstrom J, Fedida D. Single channel kinetic analysis of the cAMP effect on I(Ks) mutants, S209F and S27D/S92D. Channels (Austin). 2018 Jul 20.doi: 10.1080/19336950.2018.1499369. [Epub ahead of print] PubMed PMID: 30027808.

3. Volkers G, Lizak C, Niesser J, Rosell FI, Preidl J, Gnanapragassam VS, Horstkorte R, Rademann J, Strynadka NCJ. Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family. ACS Chem Biol. 2018 Jul 26. doi: 10.1021/acschembio.8b00478. [Epub ahead of print] PubMed PMID: 30015474.

4. Dornan GL, Dalwadi U, Hamelin DJ, Hoffmann RM, Yip CK, Burke JE. Probing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex. J Mol Biol. 2018 Jul 18. pii: S0022-2836(18)30564-3. doi: 10.1016/j.jmb.2018.07.020. [Epub ahead of print] PubMed PMID: 30031006.

Jul 23, Pubcrawler Hits:

1. Gao P, Ho PL, Yan B, Sze KH, Davies J, Kao RYT. Suppression of Staphylococcus aureus virulence by a small-molecule compound. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520. doi: 10.1073/pnas.1720520115. [Epub ahead of print] PubMed PMID: 30012613.

2. Blackmore S, Vriens B, Sorensen M, Power IM, Smith L, Hallam SJ, Mayer KU, Beckie RD. Microbial and geochemical controls on waste rock weathering and drainage quality. Sci Total Environ. 2018 Nov 1;640-641:1004-1014. doi: 10.1016/j.scitotenv.2018.05.374. Epub 2018 Jun 5. PubMed PMID: 30021267.

3. Armstrong Z, Mewis K, Liu F, Morgan-Lang C, Scofield M, Durno E, Chen HM, Mehr K, Withers SG, Hallam SJ. Metagenomics reveals functional synergy and novel polysaccharide utilization loci in the Castor canadensis fecal microbiome. ISMEJ. 2018 Jul 16. doi: 10.1038/s41396-018-0215-9. [Epub ahead of print] PubMed PMID: 30013164.

4. Wang J, Molday LL, Hii T, Coleman JA, Wen T, Andersen JP, Molday RS. Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. Sci Rep. 2018 Jul 17;8(1):10795. doi: 10.1038/s41598-018-29108-z. PubMed PMID: 30018401; PubMed Central PMCID: PMC6050252.

5. McMillan HJ, Telegrafi A, Singleton A, Cho MT, Lelli D, Lynn FC, Griffin J, Asamoah A, Rinne T, Erasmus CE, Koolen DA, Haaxma CA, Keren B, Doummar D, Mignot C, Thompson I, Velsher L, Dehghani M, Vahidi Mehrjardi MY, Maroofian R, Tchan M, Simons C, Christodoulou J, Martín-Hernández E, Guillen Sacoto MJ, Henderson LB, McLaughlin H, Molday LL, Molday RS, Yoon G. Recessive mutations in ATP8A2 cause severe hypotonia, cognitive impairment, hyperkinetic movement disorders and progressive optic atrophy. Orphanet J Rare Dis. 2018 May 31;13(1):86. doi: 10.1186/s13023-018-0825-3. PubMed PMID: 30012219; PubMed Central PMCID: PMC6048855.

6. Richter A, Strauch A, Chao J, Ko M, Av-Gay Y. Screening of preselected libraries targeting Mycobacterium abscessus for drug discovery. Antimicrob Agents Chemother. 2018 Jul 16. pii: AAC.00828-18. doi: 10.1128/AAC.00828-18. [Epub ahead of print] PubMed PMID: 30012760.

Jul 16, Pubcrawler Hits:

1. Ding H, Caza M, Dong Y, Arif AA, Horianopoulos LC, Hu G, Johnson P, Kronstad JW. ATG genes influence the virulence of Cryptococcus neoformans through contributions beyond core autophagy functions. Infect Immun. 2018 Jul 9. pii: IAI.00069-18. doi: 10.1128/IAI.00069-18. [Epub ahead of print] PubMed PMID: 29986893.

2. Lam VYY, Raineki C, Ellis L, Yu W, Weinberg J. Interactive effects of prenatal alcohol exposure and chronic stress in adulthood on anxiety-like behavior and central stress-related receptor mRNA expression: Sex- and time-dependent effects. Psychoneuroendocrinology. 2018 Jun 23;97:8-19. doi: 10.1016/j.psyneuen.2018.06.018. [Epub ahead of print] PubMed PMID: 29990678.

Jul 09, Pubcrawler Hits:

1. Vuillemin A, Horn F, Friese A, Winkel M, Alawi M, Wagner D, Henny C, Orsi WD, Crowe SA, Kallmeyer J. Metabolic potential of microbial communities from ferruginous sediments. Environ Microbiol. 2018 Jul 2. doi: 10.1111/1462-2920.14343. [Epub ahead of print] PubMed PMID: 29968357.

2. Fedida D. Modeling the Hidden Pathways of IKs Channel Activation. Biophys J. 2018 Jul 3;115(1):1-2. doi: 10.1016/j.bpj.2018.05.020. PubMed PMID: 29972801.

Jul 02, Pubcrawler Hits:

1. Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, Franzke CW, Overall CM, Granville DJ. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction. Sci Rep. 2018 Jun 26;8(1):9690. doi: 10.1038/s41598-018-28070-0. PubMed PMID: 29946113.

Jun 25, Pubcrawler Hits:

1. Snieckus V, Hurst T, Nerdinger S, Kautsjah E, Eltis L, Kahlenberg V, Schlapp-Hackl I. Bacterial Catabolism of Biphenyls. Synthesis and Evaluation of Analogues. Chembiochem. 2018 Jun 15. doi: 10.1002/cbic.201800231. [Epub ahead of print] PubMed PMID: 29905982.

2. Richard Albert J, Koike T, Younesy H, Thompson R, Bogutz AB, Karimi MM, Lorincz MC. Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA). BMC Genomics. 2018 Jun 15;19(1):463. doi: 10.1186/s12864-018-4835-2. PubMed PMID: 29907088.

3. van Pel DM, Harada K, Song D, Naus CC, Sin WC. Modelling glioma invasion using 3D bioprinting and scaffold-free 3D culture. J Cell Commun Signal. 2018 Jun 16. doi: 10.1007/s12079-018-0469-z. [Epub ahead of print] PubMed PMID: 29909492.

4. Dufour A, Bellac CL, Eckhard U, Solis N, Klein T, Kappelhoff R, Fortelny N, Jobin P, Rozmus J, Mark J, Pavlidis P, Dive V, Barbour SJ, Overall CM. C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease. Nat Commun. 2018 Jun 20;9(1):2416. doi: 10.1038/s41467-018-04717-4. PubMed PMID: 29925830.

Jun 18, Pubcrawler Hits:

1. Crowe SA, Cox RP, Jones C, Fowle DA, Santibañez-Bustos JF, Ulloa O, Canfield DE. Decrypting the sulfur cycle in oceanic oxygen minimum zones. ISME J. 2018 Jun 7; doi: 10.1038/s41396-018-0149-2. [Epub ahead of print] PubMed PMID: 29884830.

2. Khater IM, Meng F, Wong TH, Nabi IR, Hamarneh G. Super Resolution Network Analysis Defines the Molecular Architecture of Caveolae and Caveolin-1 Scaffolds. Sci Rep. 2018 Jun 13;8(1):9009. doi: 10.1038/s41598-018-27216-4. PubMed PMID: 29899348.

3. Caveney NA, Li FK, Strynadka NC. Enzyme structures of the bacterial peptidoglycan and wall teichoic acid biogenesis pathways. Curr Opin Struct Biol. 2018 Jun 6;53:45-58. doi: 10.1016/ [Epub ahead of print] Review. PubMed PMID: 29885610.

Jun 11, Pubcrawler Hits:

1. Loghmani H, Conway EM. Exploring traditional and non-traditional roles for thrombomodulin. Blood. 2018 Jun 4. pii: blood-2017-12-768994. doi: 10.1182/blood-2017-12-768994. [Epub ahead of print] PubMed PMID: 29866818.

2. Schubert P, Johnson L, Marks DC, Devine DV. Ultraviolet-Based Pathogen Inactivation Systems: Untangling the Molecular Targets Activated in Platelets. Front Med (Lausanne). 2018 May 7;5:129. doi: 10.3389/fmed.2018.00129. eCollection Review. PubMed PMID: 29868586; PubMed Central PMCID: PMC5949320.

3. Heinkel F, Shen L, Richard-Greenblatt M, Okon M, Bui JM, Gee CL, Gay LM, Alber T, Av-Gay Y, Gsponer J, McIntosh LP. Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747. Structure. 2018 May 17. pii: S0969-2126(18)30164-3. doi: 10.1016/j.str.2018.04.018. [Epub ahead of print] PubMed PMID: 29861345.

Jun 2, Pubcrawler Hits:

1. Garces F, Jiang K, Molday LL, Stöhr H, Weber BH, Lyons CJ, Maberley D, Molday RS. Correlating the Expression and Functional Activity of ABCA4 Disease Variants With the Phenotype of Patients With Stargardt Disease. Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2305-2315. doi: 10.1167/iovs.17-23364. PubMed PMID: 29847635; PubMed Central PMCID: PMC5937799

2. Grek CL, Sheng Z, Naus CC, Sin WC, Gourdie RG, Ghatnekar GG. Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics. Curr Opin Pharmacol. 2018 May 24;41:79-88. doi: 10.1016/j.coph.2018.05.002. [Epub ahead of print] Review. PubMed PMID: 29803991. 

May 28, Pubcrawler Hits:

1. Tharmarajah G, Eckhard U, Jain F, Marino G, Prudova A, Urtatiz O, Fuchs H, Hrabe de Angelis M, Overall CM, Van Raamsdonk CD. Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase. Pigment Cell Melanoma Res. 2018 May 21. doi: 10.1111/pcmr.12711. [Epub ahead of print] PubMed PMID: 29781574.

May 21, Pubcrawler Hits:

1. Siren EMJ, Chapanian R, Constantinescu I, Brooks DE, Kizhakkedathu JN. Oncotically Driven Control over Glycocalyx Dimension for Cell Surface Engineering and Protein Binding in the Longitudinal Direction. Sci Rep. 2018 May 15; 8(1):7581. doi: 10.1038/s41598-018-25870-2. PubMed PMID: 29765073.

2. Han B, Guan Q, Chafeeva I, Mendelson AA, Roza GD, Liggins R, Kizhakkedathu JN, Du C. Peritoneal and Systemic Responses of Obese Type II Diabetic Rats to Chronic Exposure to a Hyperbranched Polyglycerol-based Dialysis Solution. Basic Clin Pharmacol Toxicol. 2018 May 12. doi: 10.1111/bcpt.13038. [Epub ahead of print] PubMed PMID: 29753311.

3. Pryjma M, Burian J, Thompson CJ. Rifabutin acts in synergy and is bactericidal with frontline Mycobacterium abscessus antibiotics clarithromycin and tigecycline, suggesting a potent treatment combination. Antimicrob Agents Chemother. 2018 May 14. pii: AAC.00283-18. doi: 10.1128/AAC.00283-18. [Epub ahead of print] PubMed PMID: 29760147.

May 14, Pubcrawler Hits:

1. Li RC, Lin CC, Ren X, Wu JS, Molday LL, Molday RS, Yau KW. Ca(2+)-activated Cl current predominates in threshold response of mouse olfactory receptor neurons. Proc Natl Acad Sci U S A. 2018 May 7. pii: 201803443. doi: 10.1073/pnas.1803443115. [Epub ahead of print] PubMed PMID: 29735665.

2. Dhanda AS, Lulic KT, Vogl AW, Mc Gee MM, Chiu RH, Guttman JA. Listeria membrane protrusion collapse: Requirement of Cyclophilin A for Listeria cell-to-cell spreading. J Infect Dis. 2018 May 4. doi: 10.1093/infdis/jiy255. [Epub ahead of print] PubMed PMID: 29733369.

3. Bodnar TS, Raineki C, Wertelecki W, Yevtushok L, Plotka L, Zymak-Zakutnya N, Honerkamp-Smith G, Wells A, Rolland M, Woodward TS, Coles CD, Kable JA, Chambers CD, Weinberg J. Altered maternal immune networks are associated with adverse child neurodevelopment: Impact of alcohol consumption during pregnancy. Brain Behav Immun. 2018 May 5. pii: S0889-1591(18)30175-2. doi: 10.1016/j.bbi.2018.05.004. [Epub ahead of print] PubMed PMID: 29738852.

May 7, Pubcrawler Hits:

1. Daniel E, Daudé M, Kolotuev I, Charish K, Auld V, Le Borgne R. Coordination of Septate Junctions Assembly and Completion of Cytokinesis in Proliferative Epithelial Tissues. Curr Biol. 2018 Apr 20. pii: S0960-9822(18)30363-4. doi: 10.1016/j.cub.2018.03.034. Epub ahead of print] PubMed PMID: 29706514.

2. Laqua K, Klemm M, Richard-Greenblatt M, Richter A, Liebe L, Huang T, Lin S, Guardia A, Pérez-Herran E, Ballell L, Av-Gay Y, Imming P. Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides. Bioorg Med Chem. 2018 Apr 22. pii: S0968-0896(18)30460-7. doi: 10.1016/j.bmc.2018.04.045. [Epub ahead of print] PubMed PMID: 29706526. 

Apr 30 Pubcrawler Hits:

1. Balaton BP, Dixon-McDougall T, Peeters SB, Brown CJ. The eXceptional nature of the X chromosome. Hum Mol Genet. 2018 Apr 26. doi: 10.1093/hmg/ddy148. [Epub ahead of print] PubMed PMID: 29701779.

2. Kulkarni JA, Cullis PR, van der Meel R. Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility. Nucleic Acid Ther. 2018 Apr 23. doi: 10.1089/nat.2018.0721. [Epub ahead of print] PubMed PMID: 29683383.

3. Wang JC, Bolger-Munro M, Gold MR. Visualizing the Actin and Microtubule Cytoskeletons at the B-cell Immune Synapse Using Stimulated Emission Depletion (STED) Microscopy. J Vis Exp. 2018 Apr 9;(134). doi: 10.3791/57028. PubMed PMID: 29683438.

4. Lee-Sayer SSM, Dougan MN, Cooper J, Sanderson L, Dosanjh M, Maxwell CA, Johnson P. CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment. PLoS One. 2018 Apr 23;13(4):e0196011. doi: 10.1371/journal.pone.0196011. eCollection 2018. PubMed PMID: 29684048.

5. Stahl M, Tremblay S, Montero M, Vogl W, Xia L, Jacobson K, Menendez A, Vallance BA. The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion. Am J Physiol Gastrointest Liver Physiol. 2018 Apr 26. doi: 10.1152/ajpgi.00264.2017. [Epub ahead of print] PubMed PMID: 29698056.

6. Lillie MA, Vogl AW, Raverty S, Haulena M, McLellan WA, Stenson GB, Shadwick RE. The caval sphincter in cetaceans and its predicted role in controlling venous flow during a dive. J Exp Biol. 2018 Apr 19. pii: jeb.177212. doi: 10.1242/jeb.177212. [Epub ahead of print] PubMed PMID: 29674378.

Apr 23 Pubcrawler Hits:

1. Louca S, Polz MF, Mazel F, Albright MBN, Huber JA, O'Connor MI, Ackermann M, Hahn AS, Srivastava DS, Crowe SA, Doebeli M, Parfrey LW. Function and functional redundancy in microbial systems. Nat Ecol Evol. 2018 Apr 16. doi:10.1038/s41559-018-0519-1. [Epub ahead of print] Review. PubMed PMID: 29662222.

2. Irwin NAT, Martin BJE, Young BP, Browne MJG, Flaus A, Loewen CJR, Keeling PJ, Howe LJ. Viral proteins as a potential driver of histone depletion in dinoflagellates. Nat Commun. 2018 Apr 18; 9(1):1535. doi: 10.1038/s41467-018-03993-4. PubMed PMID: 29670105; PubMed Central PMCID: PMC5906630.

Apr 16 Pubcrawler Hits:

1. Kulkarni JA, Darjuan MM, Mercer JE, Chen S, van der Meel R, Thewalt JL, Tam YYC, Cullis PR. On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA. ACS Nano. 2018 Apr 6. doi: 10.1021/acsnano.8b01516. [Epub ahead of print] PubMed PMID: 29614232.

2. Page MM, Johnson JD. Mild Suppression of Hyperinsulinemia to Treat Obesity and Insulin Resistance. Trends in Endocrinology & Metabolism. 2018 Apr 15. DOI:

3. Dhanda AS, Vogl AW, Albraiki SE, Otey CA, Beck MR, Guttman JA. Palladin Compensates for the Arp2/3 Complex and Supports Actin Structures during Listeria Infections. MBio. 2018 Apr 10;9(2). pii: e02259-17. doi: 10.1128/mBio.02259-17. PubMed PMID: 29636431; PubMed Central PMCID: PMC5893873.

Apr 9 Pubcrawler Hits:

1. Abramyan J, Richman JM. Craniofacial development: discoveries made in the chicken embryo. Int J Dev Biol. 2018;62(1-2-3):97-107. doi: 10.1387/ijdb.170321ja. PubMed PMID: 29616744.

Apr 2 Pubcrawler Hits:

1. Crowe AM, Workman SD, Watanabe N, Worrall LJ, Strynadka NCJ, Eltis LD. IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase. Proc Natl Acad Sci U S A. 2018 Mar 26. pii: 201717015. doi:10.1073/pnas.1717015115. [Epub ahead of print] PubMed PMID: 29581275.

2. Adams WK, D'souza AM, Sussman JL, Kaur S, Kieffer TJ, Winstanley CA. Enhanced amphetamine-induced motor impulsivity and mild attentional impairment in theleptin-deficient rat model of obesity. Physiol Behav. 2018 Mar 27. pii:S0031-9384(18)30150-1. doi: 10.1016/j.physbeh.2018.03.027. [Epub ahead of print] PubMed PMID: 29601831.

3. Mafi A, Abbina S, Kalathottukaren MT, Morrissey JH, Haynes C, Kizhakkedathu JN, Pfaendtner J, Chou KC. Design of Polyphosphate Inhibitors: A Molecular Dynamics Investigation on Polyethylene Glycol-Linked Cationic Binding Groups. Biomacromolecules. 2018 Mar 23. doi: 10.1021/acs.biomac.8b00327. [Epub ahead of print] PubMed PMID: 29539260.

4. Wiesenfahrt T, Duanmu J, Snider F, Moerman D, Au V, Li-Leger E, Flibotte S, Parker DM, Marshall CJ, Osborne Nishimura E, Mains PE, McGhee JD. A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2. G3 (Bethesda). 2018 Mar 28. pii: g3.200079.2018. doi: 10.1534/g3.118.200079. [Epub ahead of print] PubMed PMID: 29593072.

5. Wang JSH, Freitas-Andrade M, Bechberger JF, Naus C, Yeung KK, Whitehead SN. MALDI IMS of Intraperitoneally Injected Danegaptide (ZP1609) for Treatment of Stroke-Reperfusion Injury in Mice. Rapid Commun Mass Spectrom. 2018 Mar 25. doi: 10.1002/rcm.8115. [Epub ahead of print] PubMed PMID: 29575411.

6. King SL, Goth CK, Eckhard U, Joshi HJ, Haue AD, Vakhrushev S, Schjoldager K, Overall CM, Wandall HH. TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation. J Biol Chem. 2018 Mar 28. pii: bc.RA118.001978. doi: 10.1074/jbc.RA118.001978. [Epub ahead of print]PubMed PMID: 29593093.

7. Kang N, Guo Q, Islamzada E, Ma H, Scott MD. Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation. Integr Biol (Camb). 2018 Mar 23. doi: 10.1039/C7IB00191F. [Epub ahead of print] PubMed PMID: 29570200.

8. Majewski DD, Worrall LJ, Strynadka NC. Secretins revealed: structural insights into the giant gated outer membrane portals of bacteria. Curr Opin Struct Biol. 2018 Mar 23;51:61-72. doi: 10.1016/ [Epub ahead of print] Review. PubMed PMID: 29579693.

9. Lam VYY, Raineki C, Takeuchi LE, Ellis L, Woodward TS, Weinberg J. Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects. Front Behav Neurosci. 2018 Mar 9;12:42. doi: 10.3389/fnbeh.2018.00042. eCollection 2018. PubMed PMID: 29593510; PubMed Central PMCID: PMC5855032.

Mar 19 Pubcrawler Hits:

1. Gardill BR, Rivera-Acevedo RE, Tung CC, Okon M, McIntosh LPVan Petegem F. The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations. Sci Rep. 2018 Mar 14;8(1):4483. doi: 10.1038/s41598-018-22713-y. PMID: 29540853.

2.  Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Dev Dyn. 2018 Mar 13. doi: 10.1002/dvdy.24626. [Epub ahead of print]. PMID: 29532564.

3. Tang WL, Tang WH, Szeitz A, Kulkarni J, Cullis P, Li SD. Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery. Biomaterials. 2018 Mar 3;166:13-26. doi: 10.1016/j.biomaterials.2018.03.004. [Epub ahead of print]. PMID: 29529479.

Mar 12 Pubcrawler Hits:

1. Foley JH, Conway EM. Basic weapons to degrade C3a and C5a. J Thromb Haemost. 2018 Mar 8. doi: 10.1111/jth.13999. [Epub ahead of print]. PMID: 29518284.

2. Conway EM. Complement-coagulation connections. Blood Coagul Fibrinolysis. 2018 Mar 6. doi: 10.1097/MBC.0000000000000720. [Epub ahead of print]. PMID: 29517503.

Feb 26 Pubcrawler Hits:

1. Cain SM, Tyson JR, Choi HB, Ko R, Lin PJC, LeDue JM, Powell KL, Bernier LP, Rungta RL, Yang Y, Cullis PR, O'Brien TJ, MacVicar BA, Snutch TP. CaV 3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons. Epilepsia. 2018 Feb 21. doi: 10.1111/epi.14018. [Epub ahead of print. PMID: 29468672.

2. Setiaputra D, Ahmad S, Dalwadi U, Steunou AL, Lu S, Ross JD, Dong MQ, Côté J, Yip CKMolecular architecture of the essential yeast histone acetyltransferase complex NuA4 redefines its multi-modularity. Mol Cell Biol. 2018 Feb 20. pii: MCB.00570-17. doi: 10.1128/MCB.00570-17. [Epub ahead of print] PMID: 29463645.

3. Wang JC, Lee JY, Dang-Lawson M, Pritchard C, Gold MR. The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center.  2018 Feb 19:0. doi: 10.1080/21541248.2018.1441626. [Epub ahead of print]. PMID: 29457987.

4. Cardenas E, Orellana LH, Konstantinidis KT, Mohn WW. Effects of timber harvesting on the genetic potential for carbon and nitrogen cycling in five North American forest ecozones. Sci Rep. 2018 Feb 16;8(1):3142. doi: 10.1038/s41598-018-21197-0. PMID: 29453368.

Feb 19 Pubcrawler Hits:

1. Millar D, Murphy L, Labrie A, Maurer-Spurej E. Routine Screening Method for Microparticles in Platelet Transfusions. J Vis Exp. 2018 Jan 31. doi: 10.3791/56893. PMID: 29443045.

2. Dommerholt MB, Dionne DA, Hutchinson DF, Kruit JK, Johnson JD. Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage. J Endocrinol. 2018 Feb 9. doi: 10.1530/JOE-17-0505. [Epub ahead of print] PMID: 29439088.

3. Jagdeo JM, Dufour A, Klein T, Solis N, Kleifeld O, Kizhakkedathu J, Luo H, Overall CMJan E. N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection. J Virol. 2018 Feb 7. doi: 10.1128/JVI.02211-17. [Epub ahead of print] PMID: 29437971.

4. Farr Zuend C, Nomellini JF, Smit JHorwitz MS. Generation of a Dual-Target, Safe, Inexpensive Microbicide that Protects Against HIV-1 and HSV-2 Disease.  2018 Feb 12;8(1):2786. doi: 10.1038/s41598-018-21134-1. PMID: 29434285.

5. Johnston ZC, Bellingham M, Filis P, Soffientini U, Hough D, Bhattacharya S, Simard M, Hammond GL, King P, O'Shaughnessy PJ, Fowler PA. The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester. BMC Med. 2018 Feb 12;16(1):23. doi: 10.1186/s12916-018-1009-7. PMID: 29429410.

Feb 12 Pubcrawler Hits:

1. Peeters SB, Korecki AJ, Simpson EM, Brown CJ. Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse. Hum Mol Genet. 2018 Feb 1. doi: 10.1093/hmg/ddy039. [Epub ahead of print] PubMed PMID: 29401310.

2. Saber N, Bruin JE, O'Dwyer S, Schuster H, Rezania A, Kieffer TJ. Sex differences in maturation of human embryonic stem cell-derived beta cells in mice. Endocrinology. 2018 Feb 5. doi: 10.1210/en.2018-00048. [Epub ahead of print] PubMed PMID: 29420708.

3. De Silva E, Kim H. Drug-induced thrombocytopenia: Focus on platelet apoptosis. Chem Biol Interact. 2018 Feb 1. pii: S0009-2797(17)30840-2. doi: 10.1016/j.cbi.2018.01.015. [Epub ahead of print] Review. PubMed PMID: 29410286.

4. Hayes M, Choudhary V, Ojha N, Shin JJ, Han GS, Carman GM, Loewen CJ, Prinz WA, Levine T. Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes. Microb Cell. 2017 Dec 28;5(2):88-103. doi: 10.15698/mic2018.02.614. PubMed PMID: 29417057; PubMed Central PMCID: PMC5798408.

5. Heger TJ, Giesbrecht IJW, Gustavsen J, Del Campo J, Kellogg CTE, Hoffman KM, Lertzman K, Mohn WW, Keeling PJ. High-throughput environmental sequencing reveals high diversity of litter and moss associated protist communities along a gradient of drainage and tree productivity. Environ Microbiol. 2018 Feb 7. doi: 10.1111/1462-2920.14061. [Epub ahead of print] PubMed PMID: 29417706.

Feb 05 Pubcrawler Hits:

1. Fakhraee M, Crowe SA, Katsev S. Sedimentary sulfur isotopes and Neoarchean ocean oxygenation. Sci Adv. 2018 Jan 24;4(1):e1701835. doi: 10.1126/sciadv.1701835. eCollection 2018 Jan. PubMed PMID: 29376118; PubMed Central PMCID: PMC5783677.

2. Devine DV. Pathogen Inactivation Strategies to Improve Blood Safety: Let's Not Throw Pathogen-Reduced Platelets Out With Their Bath Water. JAMA Oncol. 2018 Feb doi: 10.1001/jamaoncol.2017.4949. [Epub ahead of print] PubMed PMID: 29392303.

3. Wang JC, Bolger-Munro M, Gold MR. Imaging the Interactions Between B Cells and Antigen-Presenting Cells. Methods Mol Biol. 2018;1707:131-161. doi: 10.1007/978-1-4939-7474-0_10. PubMed PMID: 29388105.

4. Holert J, Cardenas E, Bergstrand LH, Zaikova E, Hahn AS, Hallam SJ, Mohn WW. Metagenomes Reveal Global Distribution of Bacterial Steroid Catabolism in Natural, Engineered, and Host Environments. MBio. 2018 Jan 30;9(1). pii:e02345-17. doi: 10.1128/mBio.02345-17. PubMed PMID: 29382738. 

Jan 29 Pubcrawler Hits:

1. Kumar P, Kizhakkedathu JN, Straus SK. Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo. Biomolecules. 2018 Jan 19;8(1). pii: E4. doi: 10.3390/biom8010004. Review. PubMed PMID: 29351202.

2. Lee AYL, Dubois CL, Sarai K, Zarei S, Schaeffer DF, Sander M, Kopp JL. Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma. Gut. 2018 Jan 23. pii: gutjnl-2017-314426. doi: 10.1136/gutjnl-2017-314426. [Epub ahead of print] PubMed PMID: 29363536.

3. Kaiser JC, King AN, Grigg JC, Sheldon JR, Edgell DR, Murphy MEP, Brinsmade SR, Heinrichs DE. Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide. PLoS Genet. 2018 Jan 22;14(1):e1007159. doi: 10.1371/journal.pgen.1007159. [Epub ahead of print] PubMed PMID: 29357354.

4. Campiglio M, Costé de Bagneaux P, Ortner NJ, Tuluc P, Van Petegem F, Flucher BE. STAC proteins associate to the IQ domain of Ca(V)1.2 and inhibit calcium-dependent inactivation. Proc Natl Acad Sci U S A. 2018 Jan 23. pii: 201715997. doi: 10.1073/pnas.1715997115. [Epub ahead of print] PubMed PMID: 29363593.

5. Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS. PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance. J Antimicrob Chemother. 2018 Jan 19. doi: 10.1093/jac/dkx531. [Epub ahead of print] PubMed PMID: 29360990.

6. Petrelli B, Weinberg J, Hicks GG. Effects of Prenatal Alcohol Exposure (PAE): Insights into FASD using PAE Mouse Models. Biochem Cell Biol. 2018 Jan 25. doi: 10.1139/bcb-2017-0280. [Epub ahead of print] PubMed PMID: 29370535.

Jan 22 Pubcrawler Hits:

1. Macdonald LC, Kim RY, Kurata HT, Fedida D. Probing the molecular basis of hERG drug block with unnatural amino acids. Sci Rep. 2018 Jan 10;8(1):289. doi: 10.1038/s41598-017-18448-x. PubMed PMID: 29321549; PubMed Central PMCID: PMC5762913.

2. Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S. Transmembrane Pickets onnect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement. Cell.  018 Jan 11;172(1-2):305-317.e10. doi: 10.1016/j.cell.2017.12.023. PubMed PMID: 29328918.

3. Bi C, Tham DKL, Perronnet C, Joshi B, Nabi IR, Moukhles H. The Oxidative Stress-Induced Increase in the Membrane Expression of the Water-Permeable Channel Aquaporin-4 in Astrocytes Is Regulated by Caveolin-1 Phosphorylation. Front Cell Neurosci. 2017 Dec 20;11:412. doi: 10.3389/fncel.2017.00412. eCollection 2017. PubMed PMID: 29326556; PubMed Central PMCID: PMC5742350.

4. Lussier AA, Morin AM, MacIsaac JL, Salmon J, Weinberg J, Reynolds JN, Pavlidis P, Chudley AE, Kobor MS. DNA methylation as a predictor of fetal alcohol spectrum disorder. Clin Epigenetics. 2018 Jan 12;10:5. doi: 10.1186/s13148-018-0439-6. eCollection 2018. PubMed PMID: 29344313; PubMed Central PMCID: PMC5767049.

5. Dalwadi U, Yip CK. Structural insights into the function of Elongator. Cell Mol Life Sci. 2018 Jan 13. doi: 10.1007/s00018-018-2747-6. [Epub ahead of print] Review. PubMed PMID: 29332244.

Jan 15 Pubcrawler Hits:

1. Linde C, Cleland JGF, Gold MR, Claude Daubert J, Tang ASL, Young JB, Sherfesee L, Abraham WT. The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. Eur J Heart Fail. 2018 Jan 4. doi: 10.1002/ejhf.1133. [Epub ahead of print] PubMed PMID: 29314424.

2. Macdonald SS, Patel A, Larmour VLC, Morgan-Lang C, Hallam SJ, Mark BL, WithersSG. Structural and mechanistic analysis of a β-glycoside phosphorylase identified by screening a metagenomic library. J Biol Chem. 2018 Jan 9. pii: jbc.RA117.000948. doi: 10.1074/jbc.RA117.000948. [Epub ahead of print] PubMed PMID: 29317495.

3. Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH. A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses. Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4. PubMed PMID: 29311608; PubMed Central PMCID: PMC5758616.

4. Lee-Sayer SSM, Maeshima N, Dougan MN, Dahiya A, Arif AA, Dosanjh M, Maxwell CA, Johnson P. Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells. Eur J Immunol. 2018 Jan 8. doi: 1002/eji.201747263. [Epub ahead of print] PubMed PMID: 29315518.

5. Solis N, Overall CM. Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS). Methods Mol Biol. 2018;1731:15-28. doi:10.1007/978-1-4939-7595-2_2. PubMed PMID: 29318539.

6. Grieco TM, Richman JM. Coordination of bilateral tooth replacement in the juvenile gecko is continuous with in ovo patterning. Evol Dev. 2018 Jan 10. doi: 1111/ede.12247. [Epub ahead of print] PubMed PMID: 29318754.

7. Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y. Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages. Sci Rep. 2018 Jan 9;8(1):155. doi: 10.1038/s41598-017-18547-9. PubMed PMID: 29317718.

Jan 8 Pubcrawler Hits:

1. Cines DB, Yarovoi SV, Zaitsev SV, Lebedeva T, Rauova L, Poncz M, Arepally GM, Khandelwal S, Stepanova V, Rux AH, Cuker A, Guo C, Ocariza LM, Travers RJ, Smith SA, Kim H, Morrissey JH, Conway EM. Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia. Blood Adv. 2016 Nov 22;1(1):62-74. doi: 10.1182/bloodadvances.2016000877. eCollection 2016 Nov 29. PubMed PMID: 29296696; PubMed Central PMCID: PMC5744055.

Jan 1 Pubcrawler Hits:

1. Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, Brömme D. Tanshinones: A novel class of ectosteric anti-resorptives. Br J Pharmacol. 2017 Dec 26. doi: 10.1111/bph.14133. [Epub ahead of print] PubMed PMID: 29278432.

2. Galibert M, Wartenberg M, Lecaille F, Saidi A, Mavel S, Joulin-Giet A, Korkmaz B, Brömme D, Aucagne V, Delmas AF, Lalmanach G. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. Eur J Med Chem. 2017 Dec 7;144:201-210. doi: 10.1016/j.ejmech.2017.12.012. [Epub ahead of print] PubMed PMID: 29272750.

3. Simard M, Underhill C, Hammond GL. Functional Implications of Corticosteroid-binding Globulin N-Glycosylation. J Mol Endocrinol. 2017 Dec 22. pii: JME-17-0234. doi: 10.1530/JME-17-0234. [Epub ahead of print] PubMed PMID: 29273683.

4. Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. Loss of PTEN and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. 2017 Dec 19. pii: S0016-5085(17)36711-2. doi: 10.1053/j.gastro.2017.12.007. [Epub ahead of print] PubMed PMID: 29273451.

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