New lipid delivery systems aim to improve potency and reduce side effects
A feature by Elie Dolgin about the promise of better fat bubbles as vehicles for vaccine contents published online today by Science Magazine begins with a quote from former LSI Director Dr. Pieter Cullis.
“This is a system that clearly has legs,” says biochemist Pieter Cullis of the University of British Columbia (UBC), Vancouver, who created the first LNPs, but “we still need to increase the efficiency of LNPs—that’s for sure.”
The story provides the history lipid nanoparticle (LNP) development, and the realization of its promise with rapid delivery of viable COVID-19 vaccines during the current pandemic.